CN108685729B - Face cream and preparation method thereof - Google Patents

Abstract

The invention discloses cannabidiol cream and a preparation method thereof, the cream comprises allantoin, xanthan gum, vitamin E, shea butter fruit oil, cetyl alcohol, prinsepia utilis royle oil, cannabidiol, purslane extract, hydrolyzed chitin, arbutin, ascorbyl glucoside, fibroin, panax notoginseng saponins and other active ingredients, and the balance is a matrix agent. The face cream can improve the absorption of the effective components of human skin, and has the effects of relieving, caring, whitening, beautifying, removing fine lines, resisting oxidation, repairing and delaying aging.

Description

Face cream and preparation method thereof

Technical Field

The invention belongs to the field of cosmetics, and particularly relates to a face cream and a preparation method thereof.

Background

With the acceleration of modern life rhythm and the increase of life working pressure, more and more people suffer from anxiety, depression and insomnia, so that the skin of people, particularly the facial skin, is aged more and more quickly; the living environment pollution is increasingly aggravated, so that the skin of people is easy to have symptoms of allergy, pigmentation, inflammatory reaction and the like. On the other hand, the living standard of people is continuously improved, the demand for caring facial skin is increasingly increased, and a huge market is provided for cosmetics with the functions of improving facial vitality, fading fine wrinkles, resisting oxidation, repairing, beautifying and delaying aging.

Most of the commercially available existing face creams only have the moisturizing effect, active ingredients are not added, and the skin problem cannot be fundamentally solved; in addition, the skin quality improvement of the facial skin is a systemic problem, and the existing products can only be improved from the outside and cannot be regulated and controlled from the immune metabolic system of a human body.

Therefore, a cream product capable of improving skin conditions from inside to outside and relieving symptoms such as allergy, pigmentation, inflammatory reaction and the like is urgently needed in the field of cosmetics.

Disclosure of Invention

Aiming at the defects in the prior art, the invention provides the face cream containing natural products such as cannabidiol, notoginsenoside, purslane extract and the like and the preparation method thereof, so that the absorption of the effective components of human skin is improved, and the effects of relieving and nursing the facial skin, whitening and beautifying, fading fine lines, resisting oxidation and repairing and delaying aging are realized.

The invention is realized by the following technical scheme:

a face cream comprises the following components (by weight percent): phase A: 42.92-69.19% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.10-0.50% of xanthan gum, 5.00% of glycerol, and phase B: 1.00-3.00% of sucrose polystearate, 0.50-2.00% of vitamin E, 3.00% of polydimethylsiloxane, 3.00-5.00% of butyrospermum parkii fruit oil, 0.10% of cetyl alcohol, 1.00-3.00% of tridecyl alcohol trimellitate, 0.10-0.20% of prinsepia utilis royle oil, 3.00% of polydimethylsiloxane, 0.50-0.80% of natural fatty alcohol (hexadecanol-octadecanol, wherein the hexadecanol-octadecanol comprises hexadecanol, heptadecanol and octadecanol), 2.00% of diethyl hexyl cyclohexane, 0.50-2.00% of cannabidiol, phase C: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-200.80%, phase D: 0.50% of phenoxyethanol and ethylhexylglycerol complex ligand, 3.00% of 1, 2-pentanediol, 0.05-0.10% of hyaluronic acid (1 ten thousand molecular weight), 0.01-0.03% of low molecular sodium hyaluronate (20 ten thousand molecular weight), 1.00-5.00% of beta-glucan, 1.00-3.00% of hexyldecanol, bisabolol, cetyl-PG hydroxyethyl palmitamide, stearic acid and brassinosteroids, 1.00-5.00% of purslane extract, 0.50-2.00% of hydrolyzed chitin, 0.10-0.50% of arbutin, 0.50-1.00% of ascorbyl glucoside, 1.00-3.00% of fibroin, 1.00-3.00% of panax notoginseng saponins, and 0.20% of propylparaben.

Preferably, the cream comprises the following components (weight percentage): phase A: 55.25% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.30% of xanthan gum, 5.00% of glycerol, and phase B: sucrose polystearate 2.00%, vitamin E1.50%, polydimethylsiloxane 3.00%, butyrospermum parkii fruit oil 4.00%, cetyl alcohol 0.10%, tridecyl alcohol trimellitate 2.00%, prinsepia utilis royle oil 0.15%, polydimethylsiloxane 3.00%, natural fatty alcohols (cetostearyl alcohol, including cetyl alcohol, heptadecyl alcohol, and stearyl alcohol) 0.65%, diethylhexylcyclohexane 2.00%, cannabidiol 1.50%, phase C: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-200.80%, phase D: 0.50% of phenoxyethanol and ethylhexylglycerin, 3.00% of 1, 2-pentanediol, 0.08% of hyaluronic acid (1 ten thousand molecular weight), 0.02% of low molecular weight sodium hyaluronate (20 ten thousand molecular weight), 3.00% of beta-glucan, 2.00% of hexyldecanol, bisabolol, cetyl-PG hydroxyethyl palmitamide, stearic acid, and campesterol, 3.00% of purslane extract, 1.50% of hydrolyzed chitin, 0.30% of arbutin, 0.80% of ascorbyl glucoside, 2.00% of fibroin, 2.00% of panax notoginseng saponins, and 0.20% of propylparaben.

The preparation method of the face cream comprises the following steps:

(1) adding the A-phase material into a water phase pot according to the formula amount, heating to 75-80 ℃, uniformly stirring, pumping into a vacuum emulsifying machine, and keeping the temperature for later use;

(2) adding the B-phase material into an oil phase pot according to the formula amount, heating to 80-85 ℃, uniformly stirring, and pumping into a vacuum emulsifying machine;

(3) starting a vacuum emulsifying machine, homogenizing and emulsifying for 15-20min, controlling the process temperature at 80-85 deg.C, adding C phase material, continuing homogenizing and emulsifying for 5-10min, and cooling;

(4) cooling to 45 deg.C, adding the D phase material, and stirring for 35-40 min;

(5) cooling to 35 deg.C, discharging, inspecting, and packaging.

The invention has the following beneficial effects:

(1) cannabidiol can repair the nervous system of a human body, has pharmacological activities of anti-spasm, anti-rheumatic arthritis, anti-anxiety, anti-depression, anti-insomnia and the like, can relieve skin after being taken into the human body through the skin, and more importantly has the effects of relieving pressure and improving sleep quality so as to improve the skin quality from inside to outside;

(2) the notoginsenoside can effectively repair the skin barrier function under UV irradiation, reduce the content of inflammatory cytokines and inhibit the expression of MMP-1, thereby playing a role in resisting skin photoaging; meanwhile, the skin care product can also promote blood circulation and make the skin ruddy and bright;

(3) the purslane extract is rich in a large amount of flavonoids, adrenalines, polysaccharides, various vitamins, amino acids and other substances, can effectively inhibit skin itch, red swelling and pain, and can prevent skin allergy to a certain extent;

(4) the fibroin is natural polymer fibrin extracted from silk, and contains 18 amino acids; the product has the effects of inhibiting tyrosinase, effectively inhibiting the generation of melanin and whitening skin; in addition, the fibroin can also promote the synthesis of collagen, activate skin cells, improve microcirculation, repair damaged skin tissues and achieve the effects of resisting aging and removing wrinkles;

(5) the arbutin can inhibit the activity of tyrosinase in vivo and prevent the generation of melanin, thereby reducing skin pigmentation, removing color spots and freckles, and simultaneously the arbutin also has the effects of sterilization and inflammation diminishing. Especially, the pseudo-ginseng extract has the effect of promoting the activity of b-16 melanocytes and can increase the generation amount of melanin, so that the fibroin and arbutin are added to achieve the effects of resisting wrinkles, whitening and delaying senescence.

Detailed Description

The following claims are presented in further detail in connection with the detailed description of the invention, but not to be construed as limiting the invention in any way, and any limited number of modifications that can be made by anyone within the scope of the claims are still within the scope of the invention.

Example 1

A face cream comprises the following components (by weight percent): phase A: 69.19% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.10% of xanthan gum, 5.00% of glycerol, and phase B: sucrose polystearate 1.00%, vitamin E0.50%, polydimethylsiloxane 3.00%, butyrospermum parkii fruit oil (corning, usa) 3.00%, cetyl alcohol 0.10%, tridecyl alcohol trimellitate 1.00%, prinsepia utilis royle oil 0.10%, polydimethylsiloxane 3.00%, natural fatty alcohol (cetostearyl alcohol) 0.50%, diethylhexylcyclohexane 2.00%, cannabidiol 0.50%, phase C: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-20 (SEPPIC, france) 0.80%, phase D: 0.50% of phenoxyethanol and ethylhexylglycerol complex ligand (Corning, USA), 3.00% of 1, 2-pentanediol, 0.05% of hyaluronic acid (1 ten thousand molecular weight), 0.01% of low molecular weight sodium hyaluronate (20 ten thousand molecular weight), 1.00% of beta-glucan, hexyldecanol and bisabolol and cetyl-PG hydroxyethyl palmitate and stearic acid and brassinosteroids (SYMRISE, Germany), 1.00% of purslane extract (Bioland, Korea), 0.50% of hydrolyzed chitin (Beijing and Chitosan Biotech, Ltd.), 0.10% of arbutin, 0.50% of ascorbyl glucoside, 1.00% of fibroin, 1.00% of Panax notoginsenosides, and 0.20% of propylparaben.

The preparation method of the face cream comprises the following steps:

(1) adding the A-phase material into a water phase pot according to the formula amount, heating to 75 ℃, uniformly stirring, pumping into a vacuum emulsifying machine, and keeping the temperature for later use;

(2) adding the B-phase material into an oil phase pot according to the formula amount, heating to 80 ℃, uniformly stirring, and pumping into a vacuum emulsifying machine;

(3) starting a vacuum emulsifying machine, homogenizing and emulsifying for 15min, controlling the process temperature at 80 ℃, adding the C-phase material, continuing homogenizing and emulsifying for 5min, and then starting cooling;

(4) cooling to 45 deg.C, adding D phase material, and stirring for 35 min;

(5) cooling to 35 deg.C, discharging, inspecting, and packaging.

Example 2

A face cream comprises the following components (by weight percent): phase A: 55.25% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.30% of xanthan gum, 5.00% of glycerol, and phase B: sucrose polystearate 2.00%, vitamin E1.50%, polydimethylsiloxane 3.00%, butyrospermum parkii fruit oil (corning, usa) 4.00%, cetyl alcohol 0.10%, tridecyl alcohol trimellitate 2.00%, prinsepia utilis royle oil 0.15%, polydimethylsiloxane 3.00%, natural fatty alcohol (cetostearyl alcohol) 0.65%, diethylhexylcyclohexane 2.00%, cannabidiol 1.50%, phase C: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-20 (SEPPIC, france) 0.80%, phase D: 0.50% of phenoxyethanol and ethylhexylglycerol complex ligand (Corning, USA), 3.00% of 1, 2-pentanediol, 0.08% of hyaluronic acid (1 ten thousand molecular weight), 0.02% of low molecular weight sodium hyaluronate (20 ten thousand molecular weight), 3.00% of beta-glucan, hexyldecanol and bisabolol and cetyl-PG hydroxyethyl palmitate and stearic acid and campesterol alcohols (SYMRISE, Germany), 3.00% of purslane extract (Bioland, Korea), 1.50% of hydrolyzed chitin (Beijing and Chitosan Biotech Co., Ltd.), 0.30% of arbutin, 0.80% of ascorbyl glucoside, 2.00% of fibroin, 2.00% of Panax notoginsenosides, and 0.20% of propylparaben.

The preparation method of the face cream comprises the following steps:

(1) adding the A-phase material into a water phase pot according to the formula amount, heating to 80 ℃, uniformly stirring, pumping into a vacuum emulsifying machine, and keeping the temperature for later use;

(2) adding the B-phase material into an oil phase pot according to the formula amount, heating to 85 ℃, uniformly stirring, and pumping into a vacuum emulsifying machine;

(3) starting a vacuum emulsifying machine, homogenizing and emulsifying for 20min, controlling the process temperature to be 85 ℃, adding the C-phase material, continuing homogenizing and emulsifying for 10min, and then starting cooling;

(4) cooling to 45 deg.C, adding D phase material, and stirring for 40 min;

(5) cooling to 35 deg.C, discharging, inspecting, and packaging.

Example 3

A face cream comprises the following components (by weight percent): phase A: 42.92% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.50% of xanthan gum, 5.00% of glycerol, and phase B: sucrose polystearate 3.00%, vitamin E2.00%, polydimethylsiloxane 3.00%, butyrospermum parkii fruit oil (corning, usa) 5.00%, cetyl alcohol 0.10%, tridecyl alcohol trimellitate 3.00%, prinsepia utilis royle oil 0.20%, polydimethylsiloxane 3.00%, natural fatty alcohol (cetostearyl alcohol) 0.80%, diethylhexylcyclohexane 2.00%, cannabidiol 2.00%, phase C: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-20 (SEPPIC, france) 0.80%, phase D: 0.50% of phenoxyethanol and ethylhexylglycerol complex ligand (Corning, USA), 3.00% of 1, 2-pentanediol, 0.10% of hyaluronic acid (1 ten thousand molecular weight), 0.03% of low molecular weight sodium hyaluronate (20 ten thousand molecular weight), 5.00% of beta-glucan, hexyldecanol and bisabolol and cetyl-PG hydroxyethyl palmitate and stearic acid and campesterol alcohols (SYMRISE, Germany), 5.00% of purslane extract (Bioland, Korea), 2.00% of hydrolyzed chitin (Beijing and Naja Biotech Co., Ltd.), 0.50% of arbutin, 1.00% of ascorbyl glucoside, 3.00% of fibroin, 3.00% of Panax notoginsenosides, and 0.20% of propylparaben.

The preparation method of the face cream comprises the following steps:

(1) adding the A-phase material into a water phase pot according to the formula amount, heating to 75 ℃, uniformly stirring, pumping into a vacuum emulsifying machine, and keeping the temperature for later use;

(2) adding the B-phase material into an oil phase pot according to the formula amount, heating to 80 ℃, uniformly stirring, and pumping into a vacuum emulsifying machine;

(3) starting a vacuum emulsifying machine, homogenizing and emulsifying for 20min, controlling the process temperature at 80 ℃, adding the C-phase material, continuing homogenizing and emulsifying for 5min, and then starting cooling;

(4) cooling to 45 deg.C, adding D phase material, and stirring for 35 min;

(5) cooling to 35 deg.C, discharging, inspecting, and packaging.

Efficacy experiments:

experiment 1: measurement of antioxidant Capacity

Free radicals are normal biochemical reaction products in the normal metabolic process of organisms, under normal conditions, the generation and elimination of the free radicals in organisms are in a dynamic balance, and when the elimination capacity of the organisms on the free radicals is weaker than the generation capacity of the organisms, the free radicals can cause damage to normal cells of human bodies, including skin cleaning, and accelerate organ aging. The scavenging ability of the active ingredients in the skin care product to free radicals is an important index.

The antioxidant capacity of the invention was compared with that of a commercially available control by selecting an in vitro model test of DPPH for radical scavenging and measuring the change in the intensity of the 517nm absorption peak spectrophotometrically.

Two imported and domestic similar products are selected to be compared with the invention for test, and the specific test method is as follows:

weighing 20mg of DPPH, and dissolving the DPPH in a 250mL brown volumetric flask by using absolute ethyl alcohol to obtain a DPPH solution with the concentration of 80 mu g/mL;

respectively and accurately weighing 0.50g of three reference substances and the cream of the invention, dissolving the three reference substances and the cream of the invention by absolute ethyl alcohol, quantitatively transferring the three reference substances and the cream of the invention into a 50mL volumetric flask, and quantitatively measuring the three reference substances and the cream of the invention to a scale by absolute ethyl alcohol to obtain the reference substances and the test solution of the invention;

adding 5.0mL of DPPH solution into 10mL of colorimetric tube, then adding the reference substance and the test solution of the invention respectively, then using absolute ethyl alcohol to fix the volume to the scale, mixing uniformly, immediately using a 1.0cm colorimetric tube to measure the absorbance at the wavelength of 517nm, marking as Ai, and then measuring the absorbance after storing for 30min in a dark place at room temperature, marking as Aj. Separately, 5.0mL of DPPH solution is taken out of a 10mL colorimetric tube, the volume is fixed to the scale by absolute ethyl alcohol, and the absorbance at 517nm is measured and is recorded as Ac. The radical clearance (K) was calculated as follows:

K(%)=[1-(Ai-Aj)/Ac]*100%

the above steps were repeated three times, and the average value was taken as the final result.

The experimental result shows that under the sampling amount of 0.50g, the clearance rate of the invention to free radicals is 37.2 percent, which is higher than that of the contrast products of commercial import (28.4 percent and 1.3 percent) and domestic products (20.7 percent), and the antioxidant capacity of the product is higher than that of the existing commercial products.

Experiment 2: control experiment for improving facial skin efficacy

In the experiment, 100 random objects are selected for group observation, the first group is an experiment group using the cream component of the preferred scheme, and the second group is a control group removing allantoin, xanthan gum, cannabidiol, purslane extract, hydrolyzed chitin, arbutin, ascorbyl glucoside, fibroin and notoginsenoside cream active components from the cream component of the preferred scheme. Two groups of subjects were used as two blinded samples and were filled out with questionnaires, and the statistical results are shown in table 1:

TABLE 1 control experiment effect on facial skin improving effect

The experimental result shows that the face cream does not cause allergic stress reaction to the facial skin of the human body, and the selected face cream substrate has good moisturizing effect; the active components in the face cream have certain auxiliary effects on relieving pressure and improving sleep, and have obvious effects on fading color spots and fine lines.

Claims (4)

1. The face cream comprises the following components in percentage by weight: phase A: 42.92-69.19% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.10-0.50% of xanthan gum, 5.00% of glycerol, and phase B: 1.00-3.00% of sucrose polystearate, 0.50-2.00% of vitamin E, 3.00% of polydimethylsiloxane, 3.00-5.00% of Butyrospermum parkii fruit oil, 0.10% of cetyl alcohol, 1.00-3.00% of tridecyl alcohol trimellitate, 0.10-0.20% of Prinsepia utilis Royle oil, 3.00% of polydimethylsiloxane, 0.50-0.80% of natural fatty alcohol, 2.00% of diethylhexylcyclohexane, 0.50-2.00% of cannabidiol, and a C phase: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-200.80%, phase D: 0.50% of phenoxyethanol and ethylhexyl glycerol complex ligand, 3.00% of 1, 2-pentanediol, 0.05-0.10% of hyaluronic acid, 0.01-0.03% of low molecular sodium hyaluronate, 1.00-5.00% of beta-glucan, 0.10-0.50% of hexyl decanol, bisabolol, cetyl-PG hydroxyethyl palmitate, 1.00-3.00% of stearic acid and brassinosteroids, 1.00-5.00% of purslane extract, 0.50-2.00% of hydrolyzed chitin, 0.10-0.50% of arbutin, 0.50-1.00% of ascorbyl glucoside, 1.00-3.00% of fibroin, 1.00-3.00% of panax notoginseng saponins and 0.20% of propylparaben; hyaluronic acid has a molecular weight of 1 ten thousand, and low-molecular sodium hyaluronate has a molecular weight of 20 ten thousand.

2. The cream according to claim 1, comprising the following components in percentage by weight: phase A: 55.25% of purified water, 0.05% of edetate disodium, 200.10% of carbomer, 0.20% of allantoin, 0.30% of xanthan gum, 5.00% of glycerol, and phase B: 2.00% of sucrose polystearate, 1.50% of vitamin E, 3.00% of polydimethylsiloxane, 4.00% of Butyrospermum parkii fruit oil, 0.10% of cetyl alcohol, 2.00% of tridecyl alcohol trimellitate, 0.15% of Prinsepia utilis Royle oil, 3.00% of polydimethylsiloxane, 0.65% of natural fatty alcohol, 2.00% of diethylhexylcyclohexane, 1.50% of cannabidiol, phase C: acrylamide/ammonium acrylate copolymer and polyisobutylene and polysorbate-200.80%, phase D: 0.50% of phenoxyethanol and ethylhexyl glycerol complex ligand, 3.00% of 1, 2-pentanediol, 0.08% of hyaluronic acid, 0.02% of low molecular sodium hyaluronate, 3.00% of beta-glucan, 3.00% of hexyldecanol and bisabolol, and 2.00% of cetyl-PG hydroxyethyl palmitamide and stearic acid and brassinosteroids, 3.00% of purslane extract, 1.50% of hydrolyzed chitin, 0.30% of arbutin, 0.80% of ascorbyl glucoside, 2% of fibroin, 2.00% of panax notoginseng saponins, and 0.20% of propylparaben.

3. The cream according to claim 1 or 2, characterized in that the natural fatty alcohol is cetostearyl alcohol.

4. A method of preparing a cream according to any one of claims 1 to 3, comprising the steps of:

(1) adding the phase A material into a water phase pot, heating to 75-80 deg.C, stirring, and pumping into a vacuum emulsifying machine; preserving heat for later use;

(2) adding the phase B material into an oil phase pot, heating to 80-85 deg.C, stirring, and pumping into a vacuum emulsifying machine;

(3) starting a vacuum emulsifying machine, homogenizing and emulsifying for 15-20min, controlling the process temperature at 80-85 deg.C, adding C phase material, continuing homogenizing and emulsifying for 5-10min, and cooling;

(4) cooling to 45 deg.C, adding the D phase material, and stirring for 35-40 min;

(5) cooling to 35 deg.C, discharging, inspecting, and packaging.