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CN108653138A - A kind of mouthwash with protection gum and mucous membrane of mouth effect - Google Patents

A kind of mouthwash with protection gum and mucous membrane of mouth effect Download PDF

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Publication number
CN108653138A
CN108653138A CN201810675494.1A CN201810675494A CN108653138A CN 108653138 A CN108653138 A CN 108653138A CN 201810675494 A CN201810675494 A CN 201810675494A CN 108653138 A CN108653138 A CN 108653138A
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CN
China
Prior art keywords
extracted solution
mouthwash
compound extracted
mushroom
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810675494.1A
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Chinese (zh)
Inventor
毛岳忠
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Han Jie Ya Technology Co Ltd
Original Assignee
Zhejiang Han Jie Ya Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Han Jie Ya Technology Co Ltd filed Critical Zhejiang Han Jie Ya Technology Co Ltd
Priority to CN201810675494.1A priority Critical patent/CN108653138A/en
Publication of CN108653138A publication Critical patent/CN108653138A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/81—Preparation or application process involves irradiation

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to nutrition and health care fields, are related to a kind of mouthwash with protection gum and mucous membrane of mouth effect.The mouthwash is by Chinese waxmyrtle bark garlic clothing grapefruit skin compound extracted solution, American Ginseng west safflower mushroom compound extracted solution, ethyl alcohol, purified water, vitamin B12, vitamin C and lactitol be prepared.The mouthwash can effectively reach protection gum and mucous membrane of mouth effect by the way of compound collecting effectively by effect ingredient compound collecting in compatibility raw material.

Description

A kind of mouthwash with protection gum and mucous membrane of mouth effect
Technical field
The present invention relates to a kind of mouthwashes with protection gum and mucous membrane of mouth effect.
Background technology
Oral health is the important component of health.The World Health Organization points out that dental health refers to tooth, tooth All tissues, oral cavity adjacent part and the equal inorganization structure of Maxillary region and dysfunction.It shows as：Cleaning of teeth, no saprodontia, no pain Pain, gingiva color is normal, no bleeding.Oral health focuses on controlling bacterial plaque, elimination dirt and swill, increases Strong physiological stimulation, making oral cavity and dentognathic system, there are one the good environments of cleaning health to safeguard mouth to play its physiological function Chamber health.Safeguard that in oral health key factor is exactly to protect gum and mucous membrane of mouth, not so it is easy to appear periodontals The case where scorching, gingivitis and canker sore, and then seriously affect the work and life of people.
Currently, many people are not noticing that oral hygiene health generally usually, be mostly periodontitis, gingivitis and It selects drug administration to cure after canker sore, there is the state mended the fold after the sheep is lost rather.Certainly, groups of people's meeting has gradually been also begun to Be used as the tool of usually oral cavity cleaning using mouthwash, but mouthrinse product currently on the market be primarily present it is following Problem：(1) there is the effect of the effect of some mouthwashes to clean oral cavity simply by gargling, then coordinate some essence, peppermint to reach To pure and fresh and refrigerant effect, oral cavity health care is actually not achieved, the oral cavity especially when there is periodontitis is strong Kangbao County protects.(2) mouthwash formula for having some powerful is chemical synthesis substance mostly, is killed using oxidation Bacterium and oxidized residual substance, are excessively used or are used for a long time in oral cavity, may destroy the normal ecological environment in oral cavity, into And injury is generated to human body.
Invention content
In view of this, the purpose of the present invention is to provide a kind of mouthwash with protection gum and mucous membrane of mouth effect, The mouthwash, can be effectively by effect ingredient compound collecting in different compatibility raw materials by the way of compound collecting, can Effectively reach protection gum and mucous membrane of mouth effect.And then by adding the raw materials such as west safflower, lactitol, oral cavity can be made refrigerant It is pure and fresh can also pre- anti-caries.
To achieve the above object, the present invention provides the following technical solutions：
1, a kind of mouthwash with protection gum and mucous membrane of mouth effect, group in parts by weight become Chinese waxmyrtle bark- Garlic clothing -80-100 parts of grapefruit skin compound extracted solution, American Ginseng-west safflower -80-100 parts of mushroom compound extracted solution, ethyl alcohol 200- 300 parts, 800-1000 parts of purified water, vitamin B1280-100 parts of 5-8 parts, 1.5-3 parts of vitamin C and lactitol.
2, wherein, Chinese waxmyrtle bark-garlic clothing-grapefruit skin compound extracted solution is by 40% Chinese waxmyrtle bark, 10% garlic clothing, 50% Grapefruit skin through crushing, mix after mixture 1,50% ethanol solution that 6 times of 1 weight of mixture is added is micro- under the conditions of 80 DEG C Wave assisted extraction filters after 4 hours to be made.
3, wherein, American Ginseng-west safflower-mushroom compound extracted solution, which is characterized in that the American Ginseng-west safflower-mushroom Compound extracted solution by 20% American Ginseng, 10% west safflower, 70% mushroom through crushing, mix after mixture 2, be added 5 times it is mixed The purified water of conjunction 2 weight of object microwave radiation exaraction under the conditions of 100 DEG C filters after 3 hours to be made.
4, the preparation of mouthwash includes following steps：
Step 1 weighs Chinese waxmyrtle bark, garlic clothing, grapefruit skin, by crushing, mixing and obtaining mixture 1；Add into mixture 1 Enter 50% ethanol solution of 6 times of weight microwave radiation exaraction under the conditions of 80 DEG C and filter after 4 hours Chinese waxmyrtle bark-garlic is made Clothing-grapefruit skin compound extracted solution.
Step 2 weighs poplar American Ginseng, west safflower, mushroom, by crushing, mixing and obtaining mixture 2；It is added into mixture 2 The purified water of 5 times of weight microwave radiation exaraction under the conditions of 100 DEG C filters obtained American Ginseng-west safflower-mushroom after 2 hours compound Extracting solution.
After being mixed formula ratio ethyl alcohol and half formula ratio purified water, the Chinese waxmyrtle bark-of formula ratio is added in step 3 Garlic clothing-grapefruit skin compound extracted solution and American Ginseng-west safflower-mushroom compound extracted solution obtain mixed liquor 1 after stirring evenly；
Step 4, by the vitamin B of half formula ratio purified water and formula ratio12, vitamin C and lactitol mixing, stirring it is equal Mixed liquor 2 is obtained after even；
Step 5 mixes mixed liquor 1 and mixed liquor 2, stir evenly to get.
The present invention has the following advantages and beneficial effects：
(1) mouthwash carries out compounding using plant material and then is extracted by functional component, makes functional component It directly discharges in the oral cavity, middle method and product effect are more notable compared with the prior art.
(2) mouthwash is extracted using plant material, and it is for harmful thin to protect gum and mucous membrane of mouth effect Bacterium itself, and by promoting mucous membrane microcirculation, removing free radical, it is anti-oxidant the effects that diminish inflammation, promote mucous membrane regeneration, phase It is safer than in the oxidation of chemical composition in the prior art.
Specific embodiment
The invention discloses a kind of mouthwashes with protection gum and mucous membrane of mouth effect, and those skilled in the art can be with Present disclosure is used for reference, parameter realization is suitably modified.In particular, it should be pointed out that all similar substitutions and modifications are to this field skill It is it will be apparent that they are considered as being included in the present invention for art personnel.Mouthwash of the present invention is by preferable Embodiment is described, related personnel obviously can not depart from the content of present invention, in spirit and scope to side as described herein Method and application are modified or suitably change and combine, to realize and apply the present invention.
Preferably to illustrate the present invention, will be illustrated below by specific embodiment.
Embodiment 1：
1, Chinese waxmyrtle bark 4000g, garlic clothing 1000g, grapefruit skin 5000g are weighed, by crushing, mixing and obtaining mixture 1；To 50% ethanol solution of 6 times of weight of addition microwave radiation exaraction under the conditions of 80 DEG C filters after 4 hours in mixture 1 is made red bayberry Bark-garlic clothing-grapefruit skin compound extracted solution.
2, American Ginseng 2000g, west safflower 1000g, mushroom 7000g are weighed, by crushing, mixing and obtaining mixture 2；To mixing It is western red to filter obtained American Ginseng-for the purified water of 5 times of weight of addition microwave radiation exaraction under the conditions of 100 DEG C in object 2 after 2 hours Flower-mushroom compound extracted solution.
3, after being mixed 15000g ethyl alcohol and 25000g purified waters, 5000g Chinese waxmyrtle barks-garlic clothing-grapefruit is added Skin compound extracted solution, 5000g American Ginseng-west safflower-mushroom compound extracted solutions obtain mixed liquor 1 after stirring evenly.
4, by 25000g purified waters and 150g vitamin Bs12, 1500g vitamin Cs and 5000g lactitols mixing, stir evenly Mixed liquor 2 is obtained afterwards.
5, mixed liquor 1 and mixed liquor 2 are mixed, stir evenly to get.
Embodiment 2：
1, Chinese waxmyrtle bark 4000g, garlic clothing 1000g, grapefruit skin 5000g are weighed, by crushing, mixing and obtaining mixture 1；To 50% ethanol solution of 6 times of weight of addition microwave radiation exaraction under the conditions of 80 DEG C filters after 4 hours in mixture 1 is made red bayberry Bark-garlic clothing-grapefruit skin compound extracted solution.
2, American Ginseng 2000g, west safflower 1000g, mushroom 7000g are weighed, by crushing, mixing and obtaining mixture 2；To mixing It is western red to filter obtained American Ginseng-for the purified water of 5 times of weight of addition microwave radiation exaraction under the conditions of 100 DEG C in object 2 after 2 hours Flower-mushroom compound extracted solution.
3, after being mixed 10000g ethyl alcohol and 20000g purified waters, 4000g Chinese waxmyrtle barks-garlic clothing-grapefruit is added Skin compound extracted solution, 4000g American Ginseng-west safflower-mushroom compound extracted solutions obtain mixed liquor 1 after stirring evenly.
4, by 20000g purified waters and 50g vitamin Bs12, 500g vitamin Cs and 4000g lactitols mixing, after stirring evenly Obtain mixed liquor 2.
5, mixed liquor 1 and mixed liquor 2 are mixed, stir evenly to get.
Embodiment 3：
The embodiment 1-2 granular preparations for preparing gained had into periodontitis, gingivitis or oral cavity to 30 clinics respectively The crowd of ulcer symptoms, everyone continuously gargles 5 days, is united after postprandial gargle 3 times, 5 days according to whether symptom improves daily Count effect.Following table is human test results：
Group Experiment number Usage time Efficiently individual quantity Invalid number It is efficient
Embodiment 1 30 5 days 26 4 86.7%
Embodiment 2 30 5 days 27 3 90.0%
As can be seen from the above table：Embodiment 1-2 prepares the efficient 86.7% or more of gained mouthwash, has good Good protection gum and mucous membrane of mouth effect.
The above is only only certain exemplary embodiments of this invention, it is noted that for the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (4)

1. a kind of mouthwash with protection gum and mucous membrane of mouth effect, which is characterized in that the mouthwash is in parts by weight Group become Chinese waxmyrtle bark-garlic clothing -80-100 parts of grapefruit skin compound extracted solution, American Ginseng-west safflower-mushroom compound extracted solution 80-100 parts, 200-300 parts of ethyl alcohol, 800-1000 parts of purified water, vitamin B121-3 parts, 10-30 parts of vitamin C and lactose 80-100 parts of alcohol.
2. according to the Chinese waxmyrtle bark described in claim 1-garlic clothing-grapefruit skin compound extracted solution, which is characterized in that the poplar Japanese apricot skin-garlic clothing-grapefruit skin compound extracted solution is by 40% Chinese waxmyrtle bark, 10% garlic clothing, 50% grapefruit skin by crushing, mixing Close after mixture 1,50% ethanol solution of 6 times of 1 weight of the mixture microwave radiation exaraction after 4 hours under the conditions of 80 DEG C is added Filtering is made.
3. according to American Ginseng-west safflower-mushroom compound extracted solution described in claim 1, which is characterized in that described the West Ginseng-west safflower-mushroom compound extracted solution is by 20% American Ginseng, 10% west safflower, 70% mushroom by crushing, mixing to obtain mixture After 2, be added the purified water of 5 times of 2 weight of mixture microwave radiation exaraction under the conditions of 100 DEG C filter after 3 hours it is obtained.
4. according to the mouthwash described in claim 1, which is characterized in that the preparation of the mouthwash includes following step Suddenly：
Step 1 weighs Chinese waxmyrtle bark, garlic clothing, grapefruit skin, by crushing, mixing and obtaining mixture 1；It is added 6 into mixture 1 50% ethanol solution of times weight microwave radiation exaraction under the conditions of 80 DEG C filters after 4 hours is made Chinese waxmyrtle bark-garlic clothing-west Shaddock ped compound extracted solution.
Step 2 weighs poplar American Ginseng, west safflower, mushroom, by crushing, mixing and obtaining mixture 2；5 times are added into mixture 2 The purified water of weight microwave radiation exaraction under the conditions of 100 DEG C filters after 2 hours to be made American Ginseng-west safflower-mushroom is compound carries Take liquid.
After being mixed formula ratio ethyl alcohol and half formula ratio purified water, Chinese waxmyrtle bark-garlic of formula ratio is added in step 3 Clothing-grapefruit skin compound extracted solution and American Ginseng-west safflower-mushroom compound extracted solution obtain mixed liquor 1 after stirring evenly；
Step 4, by the vitamin B of half formula ratio purified water and formula ratio12, vitamin C and lactitol mixing, after stirring evenly Obtain mixed liquor 2；
Step 5 mixes mixed liquor 1 and mixed liquor 2, stir evenly to get.
CN201810675494.1A 2018-06-27 2018-06-27 A kind of mouthwash with protection gum and mucous membrane of mouth effect Pending CN108653138A (en)

Priority Applications (1)

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CN201810675494.1A CN108653138A (en) 2018-06-27 2018-06-27 A kind of mouthwash with protection gum and mucous membrane of mouth effect

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Application Number Priority Date Filing Date Title
CN201810675494.1A CN108653138A (en) 2018-06-27 2018-06-27 A kind of mouthwash with protection gum and mucous membrane of mouth effect

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CN108653138A true CN108653138A (en) 2018-10-16

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101756819A (en) * 2008-10-27 2010-06-30 吉祥 Lemon mouth wash and preparation method thereof
CN102526286A (en) * 2010-12-15 2012-07-04 侯峰 Pomelo peel inflammation-diminishing and fire-clearing medicament
CN102552866A (en) * 2012-03-16 2012-07-11 刘静 Medicament for treating refractory and recurrent oral ulcer
CN104042780A (en) * 2014-06-20 2014-09-17 王玉果 Oral cavity care solution

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101756819A (en) * 2008-10-27 2010-06-30 吉祥 Lemon mouth wash and preparation method thereof
CN102526286A (en) * 2010-12-15 2012-07-04 侯峰 Pomelo peel inflammation-diminishing and fire-clearing medicament
CN102552866A (en) * 2012-03-16 2012-07-11 刘静 Medicament for treating refractory and recurrent oral ulcer
CN104042780A (en) * 2014-06-20 2014-09-17 王玉果 Oral cavity care solution

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
何富乐等: "《健康吃喝 中医食疗的全新解读 家庭珍藏版》", 31 January 2008, 上海科学技术出版社 *
夏海林等: "《营养与美容》", 30 September 2012, 华中科技大学出版社 *
李亚利: "大蒜皮化学成分及其提取物抗氧化活性研究", 《中国优秀硕士学位论文全文数据库》 *

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Application publication date: 20181016

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