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CN108403517A - A kind of dog rose flower Red blood streak dispelling composition and its application - Google Patents

A kind of dog rose flower Red blood streak dispelling composition and its application Download PDF

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Publication number
CN108403517A
CN108403517A CN201810413575.4A CN201810413575A CN108403517A CN 108403517 A CN108403517 A CN 108403517A CN 201810413575 A CN201810413575 A CN 201810413575A CN 108403517 A CN108403517 A CN 108403517A
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red blood
flower
composition
dispelling
blood streak
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不公告发明人
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Foshan Cloud Cosmetics Co Ltd
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Foshan Cloud Cosmetics Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Engineering & Computer Science (AREA)
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  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of dog roses to spend Red blood streak dispelling composition, by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed according to quality parts ratio 5 25:10‑25:8‑30:3 16 ratio composition., can be synergistic by all medicines share, reach the beauty treatment purpose for dispelling red blood, delaying skin aging.

Description

A kind of dog rose flower Red blood streak dispelling composition and its application
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of dog rose flower Red blood streak dispelling composition and its application.
Background technology
Modern female, especially white collar, since operating pressure is big, many reasons such as environmental pollution lead to the red blood of epidermis on the face Silk is apparent.And the product of many Red blood streak dispellings on the market, it is most of using chemical synthesis or hormone medicine, these substances The effects that passing through epidermal penetration enters in human body cell blood, and being used for a long time can be such that skin is damaged by different degrees of stimulation box Wound, some products are relatively mild, but only serve and cover this palliative effect, the not only not effect of Red blood streak dispelling, It is easier precipitation pigment instead, blocks pore, and makes pachylosis, pore is coarse.Therefore, a kind of Red blood streak dispelling effect is developed It is good, and product without side-effects, have a vast market foreground.
Invention content
The technical problem to be solved in the present invention is to provide a kind of dog rose flower Red blood streak dispelling composition and its applications.
The specific technical solution for solving above-mentioned technical problem is as follows:
A kind of dog rose flower Red blood streak dispelling composition, by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit Seed is according to quality parts ratio 5-25:10-25:8-30:The ratio of 3-16 forms.
Further, the Red blood streak dispelling composition is by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed According to quality parts ratio 15-20:15-20:18-24:The ratio of 8-12 forms.
Further, the preparation method of the Red blood streak dispelling composition is:By dog rose flower, ginkgo leaf, short handle open country sesame Fried dough twist and Yin Jia fruit seeds mix after crushing according to above-mentioned mass parts ratio, obtain Traditional Chinese drug mixture;By Traditional Chinese drug mixture biology sugar Glue -1- sorbierites extract, and obtain the Red blood streak dispelling composition.
The present invention, as Extraction solvent, contributes in Traditional Chinese drug mixture to have using biological carbohydrate gum -1- sorbs mixed alkoxide solution The dissolution of beneficial active constituent, then seepage pressure effects are assisted, significantly improve the recovery rate of beneficial activity ingredient.Meanwhile solvent biology sugar Without removing, the two itself is allowed for cosmetic material for glue -1, sorbierite.Biological carbohydrate gum -1 can effectively capture moisture, lock Skin reaches long-acting moistening effect;Sorbierite is that moisturizer is commonly used in cosmetics;It avoids and uses methanol, second in the prior art The organic solvents such as alcohol go solvent process as the later stage necessary to Extraction solvent.
Further, the dog rose flower, ginkgo leaf, Herba Lamii albi flower and print plus fruit seed crush after granularity be 100-150 mesh;The proportioning of the mixture and biological carbohydrate gum -1- sorbierites is 1g:(12-25)ml;The diacolation that is extracted as carries It takes;The diacolation speed of the seepage pressure effects is:10-150mL/min/kg.
Percolation is to place the medicinal material moderately crushed in percolator, constantly adds solvent by top, solvent oozed medicinal material The method that medicinal ingredient is leached during sulfate layer flows downhill is dynamic.Diacolation belongs to Dynamic Leaching method, and solvent utilization rate is high, active ingredient It leaches completely, can directly collect leachate.Relative to infusion process and reflux extraction, extraction comparison is complete, eliminates separation leaching The time of stain liquid and operation.
The present invention can effectively be enriched with the active constituent in Traditional Chinese drug mixture using quick diacolation method, obtain high-content Mixed extract, to be conducive to improve the content of effective active matter in composition;And percolation is conducive to thermal sensitivity object The extraction of matter active ingredient, makes it not convert.
Further, the method further includes the steps that following purifying:After extraction, filtering, collects supernatant at centrifugation Liquid filters the supernatant, and it is Red blood streak dispelling composition after purification to collect filtrate.
Further, the filtering is filtered using gauze, and the gauze is 150-250 mesh;The rotating speed of the centrifugation For 4000-5000r/min;The time of centrifugation is 25-35 minutes;It is filtered using filter aid diatomite in the suction filtration.
It is also another object of the present invention to provide the applications of above-mentioned Red blood streak dispelling composition.
The application provided by the present invention for dispelling red blood composition is its application in preparing cosmetics;Especially going to dispel Application in red blood face cream.
One kind removing red blood face cream of dispelling, and includes each component of following mass percentage:Above-mentioned Red blood streak dispelling composition 0.1- 10%, ribonucleic acid 0.1-3%, PEG-10 campesterols 0.1-1%, C18-36 acid glycerol three ester 1-5%, tribehenin essence PEG-20 esters 0.5-5%, tocopheryl nicotinate 0.1-3%, acrylic acid (ester) class/stearyl alcohol methacrylate copolymer 0.1-0.3%, xanthans 0.1-0.3%, acrylic acid (ester) class/C12-22 alkanol methacrylate copolymers 0.1-0.3%, PPG-5- ceteths -200.01-0.3%, polyalcohol 5-15%, Sodium Hyaluronate 0.01-0.05%, hydroxyethyl cellulose Sodium 0.05-0.3%, biological carbohydrate gum -10.1-1%, panthenol 0.1-1%, allantoin 0.01-0.1%, glycerine abietate/maleic acid Ester 0.05-0.5%, EDETATE SODIUM 0.01-0.05%, polymethyl acrylate 0.05-0.35%, agarose 0.01-0.2%, breast Sour sodium 0.2-0.4%, potassium alginate 0.01-0.2%, preservative 0.1-1%, water surplus.
Further, the polyalcohol be glycerine, 1,3 propylene glycol, 1,3 butanediols, one kind in sorbierite or it is a kind of with On mixing;The preservative is one or more kinds of mixing in potassium sorbate, sodium benzoate, Phenoxyethanol.
Above-mentioned composition is the design that herbal mixture is carried out according to the theory of traditional Chinese medical science of monarch, the dog tooth rose in the present invention Common vetch flower is a kind of wild rose, and the flower of white or pink has 5 petals, and has stamen, and it is each that wild rose is longer than the world The Temperate Region in China on ground, vascular endothelial cell are in proliferation activity, can enhance the intensity of blood vessel, can prevent skin red blood silk, to brain acyl Amine generate facilitation show that the content of sebum midbrain amide can be increased, play skin softening;Inhibition to elastoser, instead Crease-resistant performance is reflected, in conjunction with DOD sample activity, anti-aging effects is played, is monarch drug in a prescription;Ginkgo leaf:It is sweet, bitter, puckery, it puts down, promoting blood circulationization The stasis of blood is removed obstruction in channels to relieve pain, and is astringed the lung and is relievingd asthma, and turbid lipid-loweringing is changed, and is used for obstruction of collaterals by blood stasis, chest impediment and cardialgia, hemiplegia, deficiency syndrome of the lung cough and asthma, hyperlipemia Disease, glycosides displayed and flavonols in ginkgo leaf are all the street cleaners of free radical, can protect corium confluent monolayer cells, improve blood circulation, Prevent cell from generating wrinkle by oxidation.Ginkgo is one of the herbal medicine for having resistant activity gene ability, and ginkgo is in protection lipid (cell The component part of film) it is very effective from free radical injury aspect, it is ministerial drug;Herba Lamii albi flower is dicotyledon medicine Labiatae The flower of lamium plant Herba Lamii albi.Property sweet, bitter, cold, function promoting blood circulation, swelling and pain relieving, herb contain saponin, tannin, Caffeic acid and a variety of amino acid.There is activation to peroxidase activated receptor (PPAR), there are anti-inflammatory properties;Promote bud fiber The proliferation of cell, has the function of skin-active;Also there is inhibition to tyrosinase, whitening agent can be made, is adjutant;Print plus fruit: Also known as print plus peanut, plukenetia volubilis linneo are the perennial woody climber oilseed plant of Euphorbiaceae.Contain abundant oil in its fruit, Wherein 70% or more is unsaturated fatty acid, can enhance skin histology binding force, repairs sebum film, enhances the barrier work(of epidermis Energy.Transdermal dehydration is reduced, the moisturizing rate of skin is improved, soft skin increases elasticity, reduces the generation of scytitis, improves skin Skin is coarse, low and deep situation.Meanwhile the natural VE (tocopherol) of high-content and its good scavenging activated oxygen is assigned, The function of anti-aging.To make medicine.The above all medicines share, can be synergistic, reaches the beauty treatment for dispelling red blood, delaying skin aging Purpose.
The present invention has the advantages that:
The present composition by reasonable compatibility there is red blood effect of dispelling well, effectively treatment to alleviate induction type face Portion dispels red blood, and mildly non-stimulated to human skin with skin care effect;Present composition active constituent can be resisted effectively Ultraviolet light and the free radical for removing induced by ultraviolet irradiation adjust horn cell in epidermis and the functions such as divides, shift, falling off, promotion Skin wound healing, epidermis metabolism and excitation horn cell generate, and to largely improve skin texture, reach Remove the effect for red blood of dispelling.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to Routine techniques carries out.
Embodiment 1
One kind removing red blood face cream of dispelling, and includes each component of following mass percentage:Above-mentioned Red blood streak dispelling composition 10%, Ribonucleic acid 0.1%, PEG-10 campesterols 0.1%, C18-36 acid glycerol three esters 5%, tribehenin essence PEG-20 esters 0.5%, tocopheryl nicotinate 3%, acrylic acid (ester) class/stearyl alcohol methacrylate copolymer 0.3%, xanthans 0.3%, Acrylic acid (ester) class/C12-22 alkanols methacrylate copolymer 0.3%, PPG-5- ceteths -200.3%, glycerine 10%, 1,3 propylene glycol 5%, Sodium Hyaluronate 0.05%, sodium hydroxyethyl cellulose 0.3%, biological carbohydrate gum -1 0.1%, panthenol 1%, allantoin 0.01%, glycerine abietate/maleate 0.05%, EDETATE SODIUM 0.05%, polymethyl acrylate 0.05%, Agarose 0.2%, sodium lactate 0.4%, potassium alginate 0.01%, potassium sorbate 1%, water surplus.
The Red blood streak dispelling composition is by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed according to mass parts Number ratio 5:25:8:16 ratio composition.
The preparation method of the Red blood streak dispelling composition is:Dog rose flower, ginkgo leaf, Herba Lamii albi flower and print are added Fruit seed is crushed to after 150 mesh according to above-mentioned mass parts than mixing, and obtains Traditional Chinese drug mixture;By mixture and the biology mountains carbohydrate gum -1- Pears alcohol 1g in parts by weight:25ml carries out seepage pressure effects through being overpressurized percolating device, and diacolation speed is:10mL/min/kg obtains institute State Red blood streak dispelling composition.
Embodiment 2
One kind removing red blood face cream of dispelling, and includes each component of following mass percentage:Above-mentioned Red blood streak dispelling composition 0.1%, ribonucleic acid 3%, PEG-10 campesterols 1%, C18-36 acid glycerol three esters 1%, tribehenin essence PEG-20 esters 5%, tocopheryl nicotinate 0.1%, acrylic acid (ester) class/stearyl alcohol methacrylate copolymer 0.1%, xanthans 0.1%, Acrylic acid (ester) class/C12-22 alkanols methacrylate copolymer 0.1%, PPG-5- ceteths -20 0.01%, 1,3 Butanediol 5%, Sodium Hyaluronate 0.01%, sodium hydroxyethyl cellulose 0.05%, biological carbohydrate gum -1 1%, panthenol 0.1%, allantois Element 0.1%, glycerine abietate/maleate 0.5%, EDETATE SODIUM 0.01%, polymethyl acrylate 0.35%, agarose 0.01%, sodium lactate 0.2%, potassium alginate 0.2%, Phenoxyethanol 0.1%, water surplus.
The Red blood streak dispelling composition is by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed according to mass parts Number ratio 25:10:30:3 ratio composition.
The preparation method of the Red blood streak dispelling composition is:Dog rose flower, ginkgo leaf, Herba Lamii albi flower and print are added Fruit seed is crushed to after 100 mesh according to above-mentioned mass parts than mixing, and obtains Traditional Chinese drug mixture;By mixture and the biology mountains carbohydrate gum -1- Pears alcohol 1g in parts by weight:12ml carries out seepage pressure effects through being overpressurized percolating device, and diacolation speed is:150mL/min/kg is obtained The Red blood streak dispelling composition.
Embodiment 3
One kind removing red blood face cream of dispelling, and includes each component of following mass percentage:Above-mentioned Red blood streak dispelling composition 5%, Ribonucleic acid 1.5%, PEG-10 campesterols 0.5%, C18-36 acid glycerol three esters 3%, tribehenin essence PEG-20 esters 2.5%, tocopheryl nicotinate 1.5%, acrylic acid (ester) class/stearyl alcohol methacrylate copolymer 0.2%, xanthans 0.2%, acrylic acid (ester) class/C12-22 alkanols methacrylate copolymer 0.2%, PPG-5- ceteths -20 0.15%, sorbierite 10%, Sodium Hyaluronate 0.03%, sodium hydroxyethyl cellulose 0.15%, biological carbohydrate gum -1 0.5%, panthenol 0.5%, allantoin 0.06%, glycerine abietate/maleate 0.3%, EDETATE SODIUM 0.03%, polymethyl acrylate 0.15%, agarose 0.1%, sodium lactate 0.3%, potassium alginate 0.1%, sodium benzoate 0.3%, Phenoxyethanol 0.2%, more than water Amount.
The Red blood streak dispelling composition is by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed according to mass parts Number ratio 17:18:20:10 ratio composition.
The preparation method of the Red blood streak dispelling composition is:Dog rose flower, ginkgo leaf, Herba Lamii albi flower and print are added Fruit seed is crushed to after 120 mesh according to above-mentioned mass parts than mixing, and obtains Traditional Chinese drug mixture;By mixture and the biology mountains carbohydrate gum -1- Pears alcohol 1g in parts by weight:18ml carries out seepage pressure effects through being overpressurized percolating device, and diacolation speed is:60mL/min/kg obtains institute State Red blood streak dispelling composition;It after extraction, is filtered, centrifuged using the gauze of 200 mesh, collecting supernatant, centrifugation turns Speed is 4500r/min;The time of centrifugation is 30 minutes, is filtered using filter aid diatomite to the supernatant, and filter is collected Liquid is Red blood streak dispelling composition after purification.
Embodiment 4
One kind removing red blood face cream of dispelling, and includes each component of following mass percentage:Above-mentioned Red blood streak dispelling composition 3%, Ribonucleic acid 1%, PEG-10 campesterols 0.8%, C18-36 acid glycerol three esters 4%, tribehenin essence PEG-20 esters 2%, Tocopheryl nicotinate 1%, acrylic acid (ester) class/stearyl alcohol methacrylate copolymer 0.3%, xanthans 0.1%, acrylic acid (ester) class/C12-22 alkanols methacrylate copolymer 0.3%, PPG-5- ceteths -20 0.2%, 1,3 butanediols 4%, sorbierite 4%, Sodium Hyaluronate 0.02%, sodium hydroxyethyl cellulose 0.1%, biological carbohydrate gum -10.2%, panthenol 0.4%, Allantoin 0.04%, glycerine abietate/maleate 0.4%, EDETATE SODIUM 0.02%, polymethyl acrylate 0.25%, agar Sugar 0.05%, sodium lactate 0.4%, potassium alginate 0.15%, sodium benzoate 0.7%, water surplus.
The Red blood streak dispelling composition is by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed according to mass parts Number ratio 20:15:18:8 ratio composition.
The preparation method of the Red blood streak dispelling composition is:Dog rose flower, ginkgo leaf, Herba Lamii albi flower and print are added Fruit seed is crushed to after 130 mesh according to above-mentioned mass parts than mixing, and obtains Traditional Chinese drug mixture;By mixture and the biology mountains carbohydrate gum -1- Pears alcohol 1g in parts by weight:20ml carries out seepage pressure effects through being overpressurized percolating device, and diacolation speed is:100mL/min/kg is obtained The Red blood streak dispelling composition;It after extraction, is filtered, centrifuged using the gauze of 250 mesh, collecting supernatant, centrifugation Rotating speed is 4000r/min;The time of centrifugation is 25 minutes, is filtered using filter aid diatomite to the supernatant, is collected Filtrate is Red blood streak dispelling composition after purification.
Embodiment 5
One kind removing red blood face cream of dispelling, and includes each component of following mass percentage:Above-mentioned Red blood streak dispelling composition 7%, Ribonucleic acid 2%, PEG-10 campesterols 0.2%, C18-36 acid glycerol three esters 2%, tribehenin essence PEG-20 esters 4%, Tocopheryl nicotinate 2.5%, acrylic acid (ester) class/stearyl alcohol methacrylate copolymer 0.1%, xanthans 0.1%, propylene Sour (ester) class/C12-22 alkanols methacrylate copolymer 0.1%, PPG-5- ceteths -20 0.1%, glycerine 13%, Sodium Hyaluronate 0.04%, sodium hydroxyethyl cellulose 0.2%, biological carbohydrate gum -1 0.8%, panthenol 0.7%, allantoin 0.08%, glycerine abietate/maleate 0.1%, EDETATE SODIUM 0.04%, polymethyl acrylate 0.3%, agarose 0.15%, sodium lactate 0.2%, potassium alginate 0.08%, potassium sorbate 0.3%, water surplus.
The Red blood streak dispelling composition is by dog rose flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed according to mass parts Number ratio 15:20:24:12 ratio composition.
The preparation method of the Red blood streak dispelling composition is:Dog rose flower, ginkgo leaf, Herba Lamii albi flower and print are added Fruit seed is crushed to after 110 mesh according to above-mentioned mass parts than mixing, and obtains Traditional Chinese drug mixture;By mixture and the biology mountains carbohydrate gum -1- Pears alcohol 1g in parts by weight:16ml carries out seepage pressure effects through being overpressurized percolating device, and diacolation speed is:80mL/min/kg obtains institute State Red blood streak dispelling composition;It after extraction, is filtered, centrifuged using the gauze of 150 mesh, collecting supernatant, centrifugation turns Speed is 5000r/min;The time of centrifugation is 35 minutes, is filtered using filter aid diatomite to the supernatant, and filter is collected Liquid is Red blood streak dispelling composition after purification.
Comparative example 1
The difference is that, comparative example 1 is not added with dog rose flower with embodiment 3.
Comparative example 2
The difference is that, comparative example 2 is not added with ginkgo leaf with embodiment 3.
Comparative example 3
The difference is that, comparative example 3 is not added with Herba Lamii albi flower with embodiment 3.
Comparative example 4
The difference is that, comparative example 4 is not added with print plus fruit seed with embodiment 3.
1 remissive treatment induction type face of experimental example is dispelled red blood efficacy assessments
The red blood face cream that goes to dispel of 1-5 of the embodiment of the present invention and comparative example 1-4 is tried through dispel red blood patient of 450 induction type faces With age 15-26 Sui.450 subjects are divided into 9 groups at random, respectively try out embodiment 1-5 and comparative example 1-4 go to dispel it is red Blood face cream.Application method is:Subject directly uses tested products after having cleaned skin, daily to use twice, adheres to using 1 A month, the red blood face cream treatment induction type that goes to dispel is examined to dispel the effect of red blood.The evaluation criterion of curative effect is:
Recovery from illness:Face red blood of dispelling completely disappears;
It improves:Dispel red blood of face is reduced;
In vain:Face dispel red mass formed by blood stasis shape it is unchanged or aggravate.
Statistical result such as the following table 1:
Table 1
Recovery from illness It improves In vain It is efficient
Embodiment 1 8 37 5 90%
Embodiment 2 7 35 8 84%
Embodiment 3 16 32 2 96%
Embodiment 4 12 33 5 90%
Embodiment 5 13 33 4 92%
Comparative example 1 1 8 41 18%
Comparative example 2 2 7 41 18%
Comparative example 3 0 7 43 14%
Comparative example 4 1 10 39 22%
By 1 data of above-mentioned table, it is found that the red blood face cream remissive treatment induction type face that goes to dispel of the present invention is dispelled, red blood is efficient It is significant in efficacy up to 82% or more, and all subjects have no adverse reaction and the case where exacerbation of symptoms generates.
By embodiment 1-5 with comparative example 1-4 comparisons it is found that certain herbaceous plants with big flowers fruit, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed are Red blood face cream remissive treatment induction type face of dispelling is dispelled the key component of red blood, and dog rose flower, ginkgo leaf, Herba Lamii albi Effect is just notable when flower, print plus fruit seed share, and has the function of synergy.
The anti-ageing efficacy assessments of 2 moisturizing of experimental example
Inspection on probation is carried out to the red blood face cream that goes to dispel prepared by red blood face cream and comparative example 1-4 that goes to dispel prepared by embodiment 1-5 Survey effect.Test object:Each experimental group is 50 women (25-50 Sui);Persistently use 4 weeks;Test event:Elasticity of skin is imitated Fruit, moistening effect, anti-wrinkle effect.Result on trial see the table below 2:
Table 2
As can be seen from Table 2, elasticity of skin, moisturizing and the anti-wrinkle effect of the red blood face cream that goes to dispel prepared by embodiment 1-5 improve Number be significantly more than comparative example, illustrate the flower of the dog rose in the present invention, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed take With reasonable, it is able to maintain that skin moisture, improves elasticity of skin, effectively play the effect of anti-aging.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.

Claims (10)

1. a kind of dog rose spends Red blood streak dispelling composition, which is characterized in that by dog rose flower, ginkgo leaf, Herba Lamii albi Flower, print plus fruit seed are according to quality parts ratio 5-25:10-25:8-30:The ratio of 3-16 forms.
2. Red blood streak dispelling composition according to claim 1, which is characterized in that the Red blood streak dispelling composition is by dog tooth rose Common vetch flower, ginkgo leaf, Herba Lamii albi flower, print plus fruit seed are according to quality parts ratio 15-20:15-20:18-24:The ratio group of 8-12 At.
3. a kind of preparing Red blood streak dispelling composition as claimed in claim 1 or 2, which is characterized in that by dog rose flower, ginkgo Leaf, Herba Lamii albi flower and print plus fruit seed mix after crushing according to mass parts ratio as claimed in claim 1 or 2, obtain mixture; Mixture is extracted with biological carbohydrate gum -1- sorbierites, obtains the Red blood streak dispelling composition.
4. according to the method described in claim 3, it is characterized in that, dog rose flower, ginkgo leaf, Herba Lamii albi flower and Granularity after print plus fruit seed crush is 100-150 mesh;The proportioning of the mixture and biological carbohydrate gum -1- sorbierites is 1g: (12-25)m l;It is described to be extracted as seepage pressure effects;The diacolation speed of the seepage pressure effects is:10-150mL/mi n/kg.
5. method according to claim 3 or 4, which is characterized in that the method further includes the steps that following purifying:Extraction After, filtering, collects supernatant at centrifugation, is filtered to the supernatant, and it is Red blood streak dispelling after purification to collect filtrate Composition.
6. according to the method described in claim 5, it is characterized in that:The filtering is filtered using gauze, and the gauze is 150-250 mesh;The rotating speed of the centrifugation is 4000-5000r/mi n;The time of centrifugation is 25-35 minutes;It is adopted in the suction filtration It is filtered with filter aid diatomite.
7. application of the Red blood streak dispelling composition according to claim 1 or 2 in preparing cosmetics.
8. application according to claim 7, it is characterised in that:The cosmetics are to remove red blood face cream of dispelling.
9. one kind removing red blood face cream of dispelling, which is characterized in that include each component of following mass percentage:Such as claims 1 or 2 The Red blood streak dispelling composition 0.1-10%, ribonucleic acid 0.1-3%, PEG-10 campesterol 0.1-1%, C18-36 acid Triglycerides 1-5%, tribehenin essence PEG-20 esters 0.5-5%, tocopheryl nicotinate 0.1-3%, acrylic acid (ester) class/tristearin Alcohol methacrylate copolymer 0.1-0.3%, xanthans 0.1-0.3%, acrylic acid (ester) class/C12-22 alkanol metering systems Acid ester copolymer 0.1-0.3%, PPG-5- ceteth -200.01-0.3%, polyalcohol 5-15%, Sodium Hyaluronate 0.01-0.05%, sodium hydroxyethyl cellulose 0.05-0.3%, biological carbohydrate gum -10.1-1%, panthenol 0.1-1%, allantoin 0.01-0.1%, glycerine abietate/maleate 0.05-0.5%, EDETATE SODIUM 0.01-0.05%, polymethyl acrylate 0.05-0.35%, agarose 0.01-0.2%, sodium lactate 0.2-0.4%, potassium alginate 0.01-0.2%, preservative 0.1-1%, Water surplus.
10. according to claim 9 remove red blood face cream of dispelling, which is characterized in that the polyalcohol be glycerine, 1,3 propylene glycol, One or more kinds of mixing in 1,3 butanediols, sorbierite;The preservative is potassium sorbate, sodium benzoate, benzene oxygen second One or more kinds of mixing in alcohol.
CN201810413575.4A 2018-04-29 2018-04-29 A kind of dog rose flower Red blood streak dispelling composition and its application Withdrawn CN108403517A (en)

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