CN107997882A - A kind of sanitary napkin with antibacterial anti-inflammatory, analgesic efficacy and preparation method thereof - Google Patents
A kind of sanitary napkin with antibacterial anti-inflammatory, analgesic efficacy and preparation method thereof Download PDFInfo
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- CN107997882A CN107997882A CN201711287108.3A CN201711287108A CN107997882A CN 107997882 A CN107997882 A CN 107997882A CN 201711287108 A CN201711287108 A CN 201711287108A CN 107997882 A CN107997882 A CN 107997882A
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- industrial hemp
- water lock
- leaf extract
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 44
- 230000003110 anti-inflammatory effect Effects 0.000 title claims abstract description 40
- 230000000202 analgesic effect Effects 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 239000010410 layer Substances 0.000 claims abstract description 190
- 244000025254 Cannabis sativa Species 0.000 claims abstract description 128
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 claims abstract description 126
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 claims abstract description 126
- 235000009120 camo Nutrition 0.000 claims abstract description 126
- 235000005607 chanvre indien Nutrition 0.000 claims abstract description 126
- 239000011487 hemp Substances 0.000 claims abstract description 126
- 229940079593 drug Drugs 0.000 claims abstract description 122
- 239000003814 drug Substances 0.000 claims abstract description 122
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 79
- 239000011229 interlayer Substances 0.000 claims abstract description 43
- 238000004519 manufacturing process Methods 0.000 claims abstract description 22
- 239000011248 coating agent Substances 0.000 claims abstract description 9
- 238000000576 coating method Methods 0.000 claims abstract description 9
- 238000012545 processing Methods 0.000 claims abstract description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 238000001291 vacuum drying Methods 0.000 claims description 12
- 239000000047 product Substances 0.000 claims description 9
- 230000003749 cleanliness Effects 0.000 claims description 8
- 239000000835 fiber Substances 0.000 claims description 8
- 239000012467 final product Substances 0.000 claims description 8
- 238000007731 hot pressing Methods 0.000 claims description 8
- 238000007493 shaping process Methods 0.000 claims description 8
- 241000446313 Lamella Species 0.000 claims description 7
- 239000004745 nonwoven fabric Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 6
- 238000007654 immersion Methods 0.000 claims description 2
- 238000000605 extraction Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 4
- 230000001760 anti-analgesic effect Effects 0.000 abstract description 2
- 239000002131 composite material Substances 0.000 abstract 1
- 238000003825 pressing Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 16
- 239000000243 solution Substances 0.000 description 16
- 238000012360 testing method Methods 0.000 description 8
- 238000010276 construction Methods 0.000 description 7
- 230000003385 bacteriostatic effect Effects 0.000 description 6
- 239000004744 fabric Substances 0.000 description 6
- 241000588724 Escherichia coli Species 0.000 description 5
- 206010070834 Sensitisation Diseases 0.000 description 5
- 230000008313 sensitization Effects 0.000 description 5
- 229920000742 Cotton Polymers 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 239000013641 positive control Substances 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 3
- QHMBSVQNZZTUGM-UHFFFAOYSA-N Trans-Cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-UHFFFAOYSA-N 0.000 description 3
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N cannabidiol Chemical compound OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 description 3
- 229950011318 cannabidiol Drugs 0.000 description 3
- ZTGXAWYVTLUPDT-UHFFFAOYSA-N cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CC=C(C)C1 ZTGXAWYVTLUPDT-UHFFFAOYSA-N 0.000 description 3
- PCXRACLQFPRCBB-ZWKOTPCHSA-N dihydrocannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)C)CCC(C)=C1 PCXRACLQFPRCBB-ZWKOTPCHSA-N 0.000 description 3
- 239000013642 negative control Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000700199 Cavia porcellus Species 0.000 description 2
- VYZAHLCBVHPDDF-UHFFFAOYSA-N Dinitrochlorobenzene Chemical compound [O-][N+](=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 VYZAHLCBVHPDDF-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 229930003827 cannabinoid Natural products 0.000 description 2
- 239000003557 cannabinoid Substances 0.000 description 2
- 229940065144 cannabinoids Drugs 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- -1 soak 1~30 minute Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 1
- 241001060350 Acalypha Species 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- 241001087649 Eritrichium Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 229930184510 Mallotus Natural products 0.000 description 1
- 241001060384 Mallotus <angiosperm> Species 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 description 1
- 244000274883 Urtica dioica Species 0.000 description 1
- 235000009108 Urtica dioica Nutrition 0.000 description 1
- 241001123263 Zostera Species 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 229960004242 dronabinol Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000007765 extrusion coating Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000010181 skin prick test Methods 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000011032 tourmaline Substances 0.000 description 1
- 229940070527 tourmaline Drugs 0.000 description 1
- 229910052613 tourmaline Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/45—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the shape
- A61F13/47—Sanitary towels, incontinence pads or napkins
- A61F13/472—Sanitary towels, incontinence pads or napkins specially adapted for female use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/15577—Apparatus or processes for manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/84—Accessories, not otherwise provided for, for absorbent pads
- A61F13/8405—Additives, e.g. for odour, disinfectant or pH control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/84—Accessories, not otherwise provided for, for absorbent pads
- A61F13/8405—Additives, e.g. for odour, disinfectant or pH control
- A61F2013/8408—Additives, e.g. for odour, disinfectant or pH control with odour control
- A61F2013/8414—Additives, e.g. for odour, disinfectant or pH control with odour control with anti-microbic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Manufacturing & Machinery (AREA)
- Medicinal Preparation (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Abstract
The invention belongs to hygiene article sector, more particularly to a kind of sanitary napkin with antibacterial anti-inflammatory, analgesic efficacy, including hemp precoat, drug containing chip layer, drug containing water lock layer, Drain Resistance interlayer and gas permeation bottom film layer, drug containing chip layer is located under hemp precoat, drug containing water lock layer is located under drug containing chip layer, Drain Resistance interlayer is located under drug containing water lock layer, and gas permeation bottom film layer is located under Drain Resistance interlayer；Drug containing chip layer and drug containing water lock layer contain industrial hemp leaf extract；Calculated by industrial hemp leaf extract dry extract weight, drug containing chip layer is loaded with 0.01~7.00g of industrial hemp leaf extract.The production method of the sanitary napkin includes：S1, the processing of industrial hemp leaf extract；The preparation of S2, drug containing chip layer；The preparation of S3, drug containing water lock layer；It is S4, each layer is for composite；S5, week envelope pressing, folding, coating, coat, cut into individual packets dress.The present invention has effects that antibacterial anti-inflammatory, analgesic, and nonirritant.
Description
Technical field
The invention belongs to hygiene article sector, and in particular to it is a kind of with antibacterial anti-inflammatory, analgesic efficacy sanitary napkin and its
Production method.
Background technology
Sanitary napkin is a kind of material for having absorbability, and main material is cotton, non-woven fabrics, paper pulp or more material compound
The high molecular polymer and high molecular polymer extrusion coating paper formed, the design of side are mainly used to prevent side leakage, because using
When can and cotton wool body some angle be presented, it is easier to and groin stream life friction, therefore use the side of soft material
Sanitary napkin is favored compared with by women.Sanitary napkin of the prior art is by common soft cotton or chemical fibre fabric, high-polymer strong water lock
Layer, gas permeation bottom film etc. are formed.
Application publication number is 106620818 A of CN, and data of publication of application is the Chinese invention patent Shen on May 10th, 2017
Please, a kind of sanitary napkin, including top layer, internal layer, side and gum are disclosed, active ingredient green herbal medicine is filled in sanitary napkin internal layer
Powder and support beautiful jade powder parts by weight：10-15 parts of drawn grain eel grass, brave 5-10 parts of acalypha copperleaf of 5-10 portions of nurse root, 10-20 parts of big milk grass, Korea Spro
Believe 5-10 parts of grass, 30-40 parts of eritrichium pedumculare, 15-20 parts of Whitebackleaf Mallotus Root, 5-10 parts of fevervine, 5-10 parts of Tourmaline.The patent, which has, to be dissipated
Stasis of blood analgesic, anti-inflammatory anti-itch effect, still, it forms complicated.
Application publication number is 103750951 A of CN, and data of publication of application is the Chinese invention patent Shen on April 30th, 2014
Please, a kind of sanitary napkin with bactericidal antiphlogistic peace meridian and relieving pain, including nonwoven layer, Multifunctional core lamella, first are disclosed
Dust-free paper, macromolecule water uptake paper, the second dust-free paper and ventilative PE films, Multifunctional core lamella are arranged under nonwoven layer, the first nothing
Dirt paper is arranged under Multifunctional core lamella, and macromolecule water uptake paper is arranged under the first dust-free paper, and the second dust-free paper is arranged at high score
Under sub- blotting paper, ventilative PE films are arranged under the second dust-free paper.Sanitary napkin described in the patent can go to eliminate the unusual smell, but pacify warp
Analgesic and bactericidal effect and unobvious.
The content of the invention
One aspect of the present invention technical problems to be solved be to provide it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy,
To improve the antibacterial anti-inflammatory of sanitary napkin and analgesic effect.
In order to solve the above-mentioned technical problem, the technical scheme is that：
It is a kind of that there is antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, including hemp precoat, drug containing chip layer, drug containing
Water lock layer, Drain Resistance interlayer and gas permeation bottom film layer, the drug containing chip layer are located under the hemp precoat, the drug containing
Water lock layer is located under the drug containing chip layer, and the Drain Resistance interlayer is located under the drug containing water lock layer, the gas permeation bottom film
Layer is under the Drain Resistance interlayer；Hemp precoat can also be replaced with other absorbent materials in the present invention.
Hemp structure have more prismatic, loosely, there is the elongated cavity of spiral strain line and center and fiber surface to split
The characteristics of line is connected with aperture.Hemp has excellent capillary effect.Inhaled using sanitary napkin face fabric made of hemp
It is wet to perspire very good with permeability, and there is good comfort without prodding and itching feeling, user.Since hemp is distinctive
Structure and its cannabinoids material contained so that it has the function that to kill and inhibit bacteria.After measured, pure cotton fabric antibacterial
Deodorization is 0, and the antibacterial deodourizing of hemp cloth is more than 90%.
In the sanitary napkin with antibacterial anti-inflammatory, analgesic efficacy provided by the invention, it is preferable that the chip layer is drug containing
Chip layer.
In the sanitary napkin with antibacterial anti-inflammatory, analgesic efficacy provided by the invention, it is preferable that the water lock layer is drug containing
Water lock layer.
It is provided by the invention with antibacterial anti-inflammatory, analgesic efficacy sanitary napkin in, it is preferable that the drug containing chip layer and
Drug containing water lock layer contains industrial hemp leaf extract；Calculated by industrial hemp leaf extract dry extract weight, the drug containing chip
Layer is loaded with 0.01~7.00g of industrial hemp leaf extract；
In the sanitary napkin with antibacterial anti-inflammatory, analgesic efficacy provided by the invention, it is preferable that in the drug containing chip layer
It is loaded with 0.05~5.00g of industrial hemp leaf extract.
Another aspect of the present invention will solve the problems, such as to be to provide a kind of system with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy
Make method, include the following steps：
S1, the processing of industrial hemp leaf extract：Industrial hemp leaf extract dry extract is pressed into feed liquid weight ratio 1:7~12 add
Enter in 95% ethanol, fully dissolving, obtain industrial hemp leaf extract solution, it is spare；
The preparation of S2, drug containing chip layer：Multilayer hemp medical sanitary non-woven fabrics is cut into core, is dipped in step S1
In the industrial hemp leaf extract solution, soak 1~30 minute, core absorbs industrial hemp extract, by industrial hemp
Extract dry extract weight meter, the core are loaded with 0.01~7.00g of industrial hemp leaf extract；Industrial hemp will be adsorbed with
The core vacuum drying of extract, obtains drug containing chip layer, spare；
The preparation of S3, drug containing water lock layer：Water lock layer is immersed in the industrial hemp leaf extract solution described in step S1,
Immersion 1~30 minute, vacuum drying, obtains drug containing water lock layer, spare；
S4, the lower section that the drug containing water lock layer is compounded in the drug containing chip layer, cover on the drug containing chip layer top
Upper hemp precoat, is covered with Drain Resistance interlayer in the bottom of the drug containing water lock layer, is covered with the bottom of the Drain Resistance interlayer
Gas permeation bottom film layer；
S5, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S6, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
It is provided by the invention with antibacterial anti-inflammatory, analgesic efficacy sanitary napkin production method in, it is preferable that step S1
Described in industrial hemp leaf extract dry extract and 95% ethanol weight ratio be 1:10.
It is provided by the invention with antibacterial anti-inflammatory, analgesic efficacy sanitary napkin production method in, it is preferable that the core
Body soaks 10 minutes in industrial hemp leaf extract solution.
It is provided by the invention with antibacterial anti-inflammatory, analgesic efficacy sanitary napkin production method in, it is preferable that it is described to contain
Medicine core lamella is loaded with 0.05~5.00g of industrial hemp leaf extract.
The active ingredient in drug containing chip layer and drug containing water lock layer is industrial hemp leaf extract in the present invention.It is industrial big
Nettle extract raw material meet that state food drug surveilance pipe office issues on June 30th, 2014 " using cosmetic material mesh
The requirement of record notice (No. 11) ", meanwhile, also meet public security prohibition of drug department comprehensively to industrial hemp product management and control requirement, such as：《Cloud
South saves industrial hemp plantation processing license regulation》Deng requirement.Heretofore described industrial hemp extract uses specialized processes
After eliminating drug ingredient therein (such as tetrahydrocannabinol), main chemical composition is cannabidiol and other terpenes
Compound and aliphatic acid, can use safely, and the content of cannabidiol is more than 60wt%.Cannabidiol has antibacterial anti-inflammatory and analgesic
Effect.
Using above-mentioned technical proposal, since fabric is hemp fabric, its moisture absorbing and sweat releasing and permeability are very good, and
And there is good comfort without prodding and itching feeling, user.Due to the distinctive structure of hemp and its cannabinoids thing contained
Matter so that it has the function that to kill and inhibit bacteria.Drug containing chip layer and drug containing water lock are had in hemp precoat
Layer so that sanitary napkin of the invention has effects that antibacterial anti-inflammatory, analgesic.
Brief description of the drawings
Fig. 1 is a kind of structure diagram with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy of the present invention；
In figure：1- hemp precoats, 2- chip layers, 3- water lock layers, 4- Drain Resistance interlayers, 5- gas permeation bottom film layers.
Embodiment
The embodiment of the present invention is described further below in conjunction with the accompanying drawings.It should be noted that for
The explanation of these embodiments is used to help understand the present invention, but does not form limitation of the invention.It is in addition, disclosed below
As long as each embodiment of the invention in involved technical characteristic do not form conflict each other and be mutually combined.
Embodiment 1
Present embodiments provide it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, as shown in Figure 1, including hemp fibre
Dimension precoat 1, drug containing chip layer 2, drug containing water lock layer 3, Drain Resistance interlayer 4 and gas permeation bottom film layer 5, drug containing chip layer 2 are located at hemp
Under the fibrous face bed of material 1, drug containing water lock layer 3 is located under drug containing chip layer 2, and Drain Resistance interlayer 4 is located under drug containing water lock layer 3,
Gas permeation bottom film layer 5 is located under Drain Resistance interlayer 4；
Drug containing chip layer 2 and drug containing water lock layer 3 contain industrial hemp leaf extract；By industrial hemp leaf extract dry extract
Weight calculates, and drug containing chip layer 2 is loaded with industrial hemp leaf extract 0.5g；
The production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, includes the following steps:
S1, the processing of industrial hemp leaf extract：Industrial hemp leaf extract dry extract is pressed into feed liquid weight ratio 1:7 add
In 95% ethanol, fully dissolving, obtains industrial hemp leaf extract solution, spare；
The preparation of S2, drug containing chip layer 2：Multilayer hemp medical sanitary non-woven fabrics is cut into core, is dipped in step S1
In the industrial hemp leaf extract solution of middle gained, soak 5 minutes, core absorbs industrial hemp extract, is carried by industrial hemp
Thing dry extract weight meter is taken, core is loaded with industrial hemp leaf extract 0.5g；The core of industrial hemp extract will be adsorbed with
Vacuum drying, obtains drug containing chip layer 2, spare；
The preparation of S3, drug containing water lock layer 3：Water lock layer 3 is immersed to the industrial hemp leaf extract solution of gained in step S1
In, soak 3 minutes, vacuum drying, obtains drug containing water lock layer 3, spare；
S4, the lower section that drug containing water lock layer 3 is compounded in drug containing chip layer 2, hemp is covered with 2 top of drug containing chip layer
Precoat 1, is covered with Drain Resistance interlayer 4 in the bottom of drug containing water lock layer 3, gas permeation bottom film layer 5 is covered with the bottom of Drain Resistance interlayer 4；
S5, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S6, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
Embodiment 2
Present embodiments provide it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, as shown in Figure 1, including hemp fibre
Dimension precoat 1, drug containing chip layer 2, drug containing water lock layer 3, Drain Resistance interlayer 4 and gas permeation bottom film layer 5, drug containing chip layer 2 are located at hemp
Under the fibrous face bed of material 1, drug containing water lock layer 3 is located under drug containing chip layer 2, and Drain Resistance interlayer 4 is located under drug containing water lock layer 3,
Gas permeation bottom film layer 5 is located under Drain Resistance interlayer 4；
Drug containing chip layer 2 and drug containing water lock layer 3 contain industrial hemp leaf extract；By industrial hemp leaf extract dry extract
Weight calculates, and drug containing chip layer 2 is loaded with industrial hemp leaf extract 7.00g；
The production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, includes the following steps:
S1, the processing of industrial hemp leaf extract：Industrial hemp leaf extract dry extract is pressed into feed liquid weight ratio 1:12 add
In 95% ethanol, fully dissolving, obtains industrial hemp leaf extract solution, spare；
The preparation of S2, drug containing chip layer 2：Multilayer hemp medical sanitary non-woven fabrics is cut into core, is dipped in step S1
In the industrial hemp leaf extract solution of middle gained, soak 30 minutes, core absorbs industrial hemp extract, is carried by industrial hemp
Thing dry extract weight meter is taken, core is loaded with industrial hemp leaf extract 7.00g；The core of industrial hemp extract will be adsorbed with
Vacuum drying, obtains drug containing chip layer 2, spare；
The preparation of S3, drug containing water lock layer 3：Water lock layer 3 is immersed to the industrial hemp leaf extract solution of gained in step S1
In, soak 28 minutes, vacuum drying, obtains drug containing water lock layer 3, spare；
S4, the lower section that drug containing water lock layer 3 is compounded in drug containing chip layer 2, hemp is covered with 2 top of drug containing chip layer
Precoat 1, is covered with Drain Resistance interlayer 4 in the bottom of drug containing water lock layer 3, gas permeation bottom film layer 5 is covered with the bottom of Drain Resistance interlayer 4；
S5, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S6, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
Embodiment 3
Present embodiments provide it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, as shown in Figure 1, including hemp fibre
Dimension precoat 1, drug containing chip layer 2, drug containing water lock layer 3, Drain Resistance interlayer 4 and gas permeation bottom film layer 5, drug containing chip layer 2 are located at hemp
Under the fibrous face bed of material 1, drug containing water lock layer 3 is located under drug containing chip layer 2, and Drain Resistance interlayer 4 is located under drug containing water lock layer 3,
Gas permeation bottom film layer 5 is located under Drain Resistance interlayer 4；
Drug containing chip layer 2 and drug containing water lock layer 3 contain industrial hemp leaf extract；By industrial hemp leaf extract dry extract
Weight calculates, and drug containing chip layer 2 is loaded with industrial hemp leaf extract 5.00g；
The production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, includes the following steps:
S1, the processing of industrial hemp leaf extract：Industrial hemp leaf extract dry extract is pressed into feed liquid weight ratio 1:10 add
In 95% ethanol, fully dissolving, obtains industrial hemp leaf extract solution, spare；
The preparation of S2, drug containing chip layer 2：Multilayer hemp medical sanitary non-woven fabrics is cut into core, is dipped in step S1
In the industrial hemp leaf extract solution of middle gained, soak 20 minutes, core absorbs industrial hemp extract, is carried by industrial hemp
Thing dry extract weight meter is taken, core is loaded with industrial hemp leaf extract 5.00g；The core of industrial hemp extract will be adsorbed with
Vacuum drying, obtains drug containing chip layer 2, spare；
The preparation of S3, drug containing water lock layer 3：Water lock layer 3 is immersed to the industrial hemp leaf extract solution of gained in step S1
In, soak 15 minutes, vacuum drying, obtains drug containing water lock layer 3, spare；
S4, the lower section that drug containing water lock layer 3 is compounded in drug containing chip layer 2, hemp is covered with 2 top of drug containing chip layer
Precoat 1, is covered with Drain Resistance interlayer 4 in the bottom of drug containing water lock layer 3, gas permeation bottom film layer 5 is covered with the bottom of Drain Resistance interlayer 4；
S5, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S6, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
Embodiment 4
Present embodiments provide it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, as shown in Figure 1, including hemp fibre
Dimension precoat 1, drug containing chip layer 2, drug containing water lock layer 3, Drain Resistance interlayer 4 and gas permeation bottom film layer 5, drug containing chip layer 2 are located at hemp
Under the fibrous face bed of material 1, drug containing water lock layer 3 is located under drug containing chip layer 2, and Drain Resistance interlayer 4 is located under drug containing water lock layer 3,
Gas permeation bottom film layer 5 is located under Drain Resistance interlayer 4；
Drug containing chip layer and drug containing water lock layer contain industrial hemp leaf extract；By industrial hemp leaf extract dry extract weight
Amount calculates, and drug containing chip layer 2 is loaded with industrial hemp leaf extract 3.00g；
The production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, includes the following steps:
S1, the processing of industrial hemp leaf extract：Industrial hemp leaf extract dry extract is pressed into feed liquid weight ratio 1:8 add
In 95% ethanol, fully dissolving, obtains industrial hemp leaf extract solution, spare；
The preparation of S2, drug containing chip layer 2：Multilayer hemp medical sanitary non-woven fabrics is cut into core, is dipped in step S1
In the industrial hemp leaf extract solution of middle gained, soak 10 minutes, core absorbs industrial hemp extract, is carried by industrial hemp
Thing dry extract weight meter is taken, core is loaded with industrial hemp leaf extract 3.00g；The core of industrial hemp extract will be adsorbed with
Vacuum drying, obtains drug containing chip layer 2, spare；
The preparation of S3, drug containing water lock layer 3：Water lock layer 3 is immersed to the industrial hemp leaf extract solution of gained in step S1
In, soak 20 minutes, vacuum drying, obtains drug containing water lock layer 3, spare；
S4, the lower section that drug containing water lock layer 3 is compounded in drug containing chip layer 2, hemp is covered with 2 top of drug containing chip layer
Precoat 1, is covered with Drain Resistance interlayer 4 in the bottom of drug containing water lock layer 3, gas permeation bottom film layer 5 is covered with the bottom of Drain Resistance interlayer 4；
S5, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S6, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
Embodiment 5
Present embodiments provide it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, as shown in Figure 1, including hemp fibre
Tie up precoat 1, chip layer 2, water lock layer 3, Drain Resistance interlayer 4 and gas permeation bottom film layer 5, chip layer 2 be located at hemp precoat 1 it
Under, water lock layer 3 is located under chip layer 2, and Drain Resistance interlayer 43 is located under water lock layer, gas permeation bottom film layer 5 be located at Drain Resistance interlayer 4 it
Under.
The production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, includes the following steps：
S1, the lower section that water lock layer 3 is compounded in chip layer 2, are covered with hemp precoat 1 on 2 top of chip layer, are locking
The bottom of water layer 3 is covered with Drain Resistance interlayer 4, and gas permeation bottom film layer 5 is covered with the bottom of Drain Resistance interlayer 4；
S2, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S3, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
Embodiment 6
Sanitary napkin, including nonwoven layer, chip layer, water lock layer, Drain Resistance interlayer and gas permeation bottom film layer are present embodiments provided,
Chip layer is located under nonwoven layer, and water lock layer is located under chip layer, and Drain Resistance interlayer is located under water lock layer, gas permeation bottom film layer
Under Drain Resistance interlayer.
The production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, includes the following steps：
S1, the lower section that water lock layer is compounded in chip layer, are covered with nonwoven layer, in the bottom of water lock layer on chip layer top
Drain Resistance interlayer is covered with, gas permeation bottom film layer is covered with the bottom of Drain Resistance interlayer；
S2, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make production
Product sound construction；
S3, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
Test example
The sanitary napkin of the gained of embodiment 1 to 6 is tested.
1.1 animal albino guinea-pigs 128, are provided by Beijing Vital River Experimental Animals Technology Co., Ltd., and weight 215~
264g。
1.2 test strain Escherichia coli (8099)；Staphylococcus aureus (ATCC6538).
1.3 equipment culture mediums:TSA.Dilution:Phosphate buffer.
1.4 test method
1.4.1 the allergy experiment gained sanitary napkin of Example 1 to 6, is cut into 2cm × 2cm sizes as tested material.It is dynamic
Thing is randomly divided into 7 groups, and the group of embodiment 1 to 5, negative control group, positive controls (2,4- dinitro-chloro-benzene) every group 16 are female
It is male fifty-fifty.24h before experiment, by unhairing on the left of guinea pig back, scope is 3cm × 3cm.Tested material is attached on 2cm × 2cm gauzes
(negative control group does not paste tested material, and positive controls apply 2,4- dinitro-chloro-benzenes on gauze), then it is affixed on animal unhaired hide
On skin, covered with nonirritant oilpaper, then 6h is fixed with non-stimulated adhesive plaster.7d and 14d in kind repeats 1
It is secondary.It after last induces 14d, will as former state be coated on 2cm × 2cm gauzes, be applied on the right side of guinea pig back and go to hair-fields (before contact
24h cropping, scope are 3cm × 3cm), remove tested material after closing fixed 6h, respectively at 24h and 48h observation dermoreactions, root
Score according to dermoreaction standards of grading.Negative control group only gives tested material excitation processing.The operation sequence of positive controls is same
Test group, tested material is substituted with positive sensitizer.Its sensitization intensity is evaluated according to sensitization rate during off-test.It the results are shown in Table 1.
1. Skin allergy test result of table
As can be seen from Table 1, the sensitization rate of positive controls is 75%, and the sensitization rate of 6 groups of embodiment is 50%, embodiment
5 groups of sensitization rate is 12.5%, and the group of embodiment 1 to 4 is acted normally.Therefore, the obtained sanitary napkin of the present invention does not have skin
It is irritant.
1.4.2 bacteriostatic test takes sequin with being beaten on the sanitary napkin obtained by 5mm card punch from each embodiment, in aseptic condition
Lower to be placed in sequin on the culture medium for having cultivated Escherichia coli and staphylococcus aureus, control group uses sterile 5mm diameters
Circular Xinhua's No.1 qualitative filter paper replaces Small-size napkin sequin.Each test group does 2 parallel tests.It is straight to measure antibacterial ring size
Footpath.It the results are shown in Table 2.
2. bacteriostatic test result of table
As can be seen from Table 2, blank control to Escherichia coli and staphylococcus aureus without bacteriostatic activity, embodiment 1
There is good bacteriostatic activity to Escherichia coli and staphylococcus aureus to 4 groups, 5 groups of embodiment is to Escherichia coli and golden yellow
Staphylococcic bacteriostatic activity is higher than embodiment 6, and the bacteriostatic activity that 6 groups of embodiment is substantially less than the group of embodiment 1 to 4.Therefore, originally
The sanitary napkin of invention has significant fungistatic effect.
Embodiments of the present invention are explained in detail above in association with attached drawing, but the invention is not restricted to described implementation
Mode.For a person skilled in the art, in the case where not departing from the principle of the invention and spirit, to these embodiments
A variety of change, modification, replacement and modification are carried out, are still fallen within protection scope of the present invention.
Claims (9)
1. it is a kind of have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that including hemp precoat, chip layer,
Water lock layer, Drain Resistance interlayer and gas permeation bottom film layer, the chip layer are located under the hemp precoat, the water lock layer position
Under the chip layer, the Drain Resistance interlayer is located under the water lock layer, the gas permeation bottom film layer be located at the Drain Resistance every
Under layer.
2. according to claim 1 have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that the chip layer
For drug containing chip layer.
3. according to claim 2 have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that the water lock layer
For drug containing water lock layer.
4. according to claim 3 have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that the drug-containing core
Lamella and drug containing water lock layer contain industrial hemp leaf extract；Calculated by industrial hemp leaf extract dry extract weight, it is described to contain
Medicine core lamella is loaded with 0.01~7.00g of industrial hemp leaf extract.
5. according to claim 4 have antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that the drug-containing core
Lamella is loaded with 0.05~5.00g of industrial hemp leaf extract.
6. a kind of production method with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that include the following steps：
S1, the processing of industrial hemp leaf extract：Industrial hemp leaf extract dry extract is pressed into feed liquid weight ratio 1:7~12 add
In 95% ethanol, fully dissolving, obtains industrial hemp leaf extract solution, spare；
The preparation of S2, drug containing chip layer：Multilayer hemp medical sanitary non-woven fabrics is cut into core, is dipped in described in step S1
Industrial hemp leaf extract solution in, soak 1~30 minute, core absorb industrial hemp extract, extracted by industrial hemp
Thing dry extract weight meter, the core are loaded with 0.01~7.00g of industrial hemp leaf extract；Industrial hemp extraction will be adsorbed with
The core vacuum drying of thing, obtains drug containing chip layer, spare；
The preparation of S3, drug containing water lock layer：Water lock layer is immersed in the industrial hemp leaf extract solution described in step S1, immersion
1~30 minute, vacuum drying, obtained drug containing water lock layer, spare；
S4, the lower section that the drug containing water lock layer is compounded in the drug containing chip layer, are covered with greatly on the drug containing chip layer top
Flaxen fiber precoat, Drain Resistance interlayer is covered with the bottom of the drug containing water lock layer, is covered with the bottom of the Drain Resistance interlayer ventilative
Bottom membrane；
S5, in the environment of 1,000,000 grades of cleanliness factors, through pressure roller hot pressing under conditions of being 100 DEG C in temperature, week envelope, make product knot
Structure is firm；
S6, release liners bonding, shaping are cut in week, and folding, coating, coat, cut into individual packets dress, to obtain the final product.
7. the production method according to claim 6 with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that
The weight ratio of industrial hemp leaf extract dry extract and 95% ethanol described in step S1 is 1:10.
8. the production method according to claim 6 with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that
The core soaks 10 minutes in industrial hemp leaf extract solution.
9. the production method according to claim 6 with antibacterial anti-inflammatory, the sanitary napkin of analgesic efficacy, it is characterised in that
The drug containing chip layer is loaded with 0.05~5.00g of industrial hemp leaf extract.
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| CN112891604A (en) * | 2021-01-19 | 2021-06-04 | 哈尔滨宝邦生物科技发展有限公司 | Sanitary pad manufacturing process added with CBD coating |
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Application publication date: 20180508 |