CN1079257C

CN1079257C - Powder medicine for treating born and scald

Info

Publication number: CN1079257C
Application number: CN99112563A
Authority: CN
Inventors: 唐永奎
Original assignee: Individual
Current assignee: Individual
Priority date: 1999-11-16
Filing date: 1999-11-16
Publication date: 2002-02-20
Anticipated expiration: 2019-11-16
Also published as: CN1295848A

Abstract

A powdery medicine of the present invention for treating burns and scalds is prepared from the following raw materials: 1 to 5 portions by weight of egg internal membranes, 5 to 10 portions by weight of biota leaves, 5 to 10 portions by weight of frostbitten malberry leaves, 5 to 10 portions by weight of dahurian angelica roots, 5 to 10 portions by weight of frankincense, 5 to 10 portions by weight of myrrh, 5 to 10 portions by weight of sanguisorba roots, 5 to 10 portions by weight of Chinese ilex leaves, 5 to 10 portions by weight of aloes, 1 to 5 portions by weight of borneol and 0.25 to 0.3 portion by weight of zinc sulphate. The effectiveness ratio of the present invention for treating various burns and scalds is 100%, the curative ratio is 100%, skin grafting does not need to be carried out, and scars can not be left.

Description

Powder medicine for treating born and scald

The invention belongs to the external used medicine of treatment burn and scald.

At present, the external used medicine of treatment burn is many, and prescription is had nothing in common with each other, and effect is different.As moist expose burn ointment commonly used clinically to small size superficial burns curative effect also can, but undesirable to the deep second degree burn therapeutic effect, third degree burn is invalid substantially, needs by skin-grafting elimination wound surface.At present, general in the world silver sulfadiazine is mainly used in the dry wound surface of burn, the skin-grafting of selecting a good opportunity, no granulation promoting function.

Purpose of the present invention also provides a kind of external used medicine for the treatment of burn, and manufacturing process is simple, and curative effect is reliable, can cure all kinds of burn and scald effectively, and anti-infection ability is strong, and effect is fast, and 30% area need not made skin graft with interior burn and scald.

Powder medicine for treating born and scald of the present invention is to be made by the raw material by following parts by weight:

1～5 part of egg membrane, side uncle leaf 5～10, Folium Mori 5～10, the Radix Angelicae Dahuricae 5～10, Olibanum 5～10, Myrrha 5～10, Radix Sanguisorbae 5～10, Folium Ilicis Purpureae 5～10, Aloe 5～10, Borneolum Syntheticum 1～5, zinc sulfate 0.25～0.3.

In above-mentioned raw materials, also can comprise in the following raw material one or more: catechu 5～10, Herba Centellae 5～10, Mirabilitum crystallina 5～10.

Egg membrane is one deck tunica albuginea in the Ovum crusta Gallus domesticus, and it acts on the cough-relieving record in the Compendium of Material Medica.It contains protein, collagen composition, is used for burn and scald and makes the wound surface convergence granulation promoting.Zinc sulfate belongs to chemical drugs, is the indispensable trace element of human body, and zinc can be kept epithelial normal reparation, fibroblast proliferation, epithelium formation, collagen is synthesized play an important role.Other Chinese medicine ingredients contains tannin, volatile oil, aminoacid, organic acid, various vitamin, flavonoid glycoside etc.The present invention forms science, mainly acts on removing heat from blood, hemostasis, convergence, pain relieving, granulation promoting, sterilization, infection, inhibition cicatrization.This medicine should be given birth to usefulness, is medicine for external use, and preparation method is simple, and each component is mixed, pulverized, and sieving gets final product.

Curative effect of the present invention is reliable, has no side effect, to treating all kinds of burn and scald effective percentage 100%, cure rate 100%.The present invention also has very strong epilepsy therapeutical effect.Consumption is few, and effect is fast, clinically is used for the treatment of all kinds of burn and scald, and 60% area infects two degree burn and scald with interior nothing, and topical agent is once cured preventing from scar in 15～20 days after conventional infection, supporting treatment, the debridement.30% area, need not made skin graft through several or tens topical agents with three interior degree burn and scald.To this, treat early preventing from scar; If infect, treat untimelyly, can stay cicatrix to some extent.10～12 hours dryings behind the topical agent of the present invention form an airtight protective layer, stop body fluid to ooze out, and prevent outside antibacterial intrusion.All kinds of burn and scald 1216 examples of clinical treatment, existing 168 routine patients are wherein done following clinical report:

One, case is selected:

1,1～16 years old 67 example among the 168 routine patients, 17～67 years old 101 example; Male's 126 examples, women's 42 examples.

2, sulphuric acid, alkaline burn, Colophonium 17 examples of burning; Gasoline, liquefied gas 38 examples of burning; Electric injury 1 example; Boiling property liquid is scalded 112 examples.Wherein women's head-ornaments portion, cervical region, hands, trunk, breast, foot burn and scald 69 examples, 99 examples are extremity position wound.

3, burn and scald area minimum 1%, maximum 55%.

4, the burn and scald degree of depth: two degree 1%～55% area 142 examples, two degree burn and scald infect to 3-degree wound and three degree burn and scald 1%～30% with inner area 26 examples.

5, burn and scald classification: slight 86 examples, moderate 44 examples, severe 15 examples, extra heavy 3 examples.

6, consultation time: 87 examples in 12 hours, 59 examples in 24～72 hours, 22 examples in 4 days～30 days.

Two, diagnostic criteria:

1, by the caused damage of heating power (flame, scorching hot, gas, liquid or solid etc.).

2, the burn and scald area is estimated: Chinese rule of Nine

3, burn and scald estimation of Depth: three degree quarterings

4, burn and scald degree classification: the criteria for classification that whole nation burn meeting in 1970 is drafted

(1) slight burn and scald: the gross area is at the degree of two below 9% burn and scald;

(2) moderate burn and scald: the gross area is between 10%～29%, or three degree burn and scald areas are below 10%;

(3) severe burn and scald: the gross area is between 30%～49%, or three degree burn and scald area between 10%～19% or burn and scald area less than 30%, but one of following situation person is arranged: (1) whole body situation is heavier or suffered a shock, and (2) combined injury is in (3), moderate and severe inhalation;

(4) extra heavy burn and scald: the gross area is more than 50%, or three degree burn and scald areas are more than 20%.

Three, clinical treatment:

Therapeutic Method: conventional debridement, infection, supporting treatment: after the debridement powder medicine for treating born and scald of the present invention is sprinkling upon on the wound surface equably, thick about 0.3～0.5 millimeter exposes wound surface.

Four, efficacy evaluation:

1, FFI topical agent below 60% is cured preventing from scar in one time 15～20 days.

2,10% with three interior degree burn and scald, and wound surface does not have infection, and medication need not made skin graft preventing from scar for several times.

3, two degree burn and scald with the treatment of other method surpass the disunion of first quarter moon wound surface or and infect, small size three degree burn and scald treatments surpass first quarter moon, use the present invention's treatment instead, after healing in various degree leave cicatrix.

4, Drug therapy of the present invention is promptly used at face, hands, function of joint position after the wound, more the no cicatrix in back.Function is unaffected.

5, except strong acid, the highly basic burn and scald

6, except the severe muscle burn and scald.

Five: characteristics

1, FFI two degree empyrosis wound surface medications are once cured, and do not need the stimulation wound surface of changing dressings every day.

2,30% with three interior degree empyrosis wound surface medications, and medication according to circumstances is for several times to tens of healings.

3,10～12 hours dryings behind the topical agent form an airtight protective layer, stop body fluid to ooze out, and prevent outside antibacterial intrusion.

4, aseptic condition is not strict, alleviates medical personnel's workload.

5, routine blood test, biochemical analysis is no abnormal.

6, in above-mentioned 42 routine female patients, there are 2 examples to burn because of epilepsy grand mal.An example burn head wherein, an example burn breast, abdomen, lower limb.The patient of head burn, after burn was cured, epileptics was also cured, not recurrence in 9 years so far.Another routine patient, after burn was cured, epilepsy was cured substantially, and under insensibility stimulated, oneself can the controlling symptoms outbreak.

Six, case introduction

Example one: the week * *, man 32 years old, the gas that is liquefied burn, women's head-ornaments, neck, breast, abdomen, extremity portion, both hands, the second degree burn area is about 55%, and conventional anti-infective therapy adds supporting treatment, and the external powder medicine for treating born and scald was cured preventing from scar in one time 15 days.

Example two: the king * *, the woman, 26 years old, by the two lower limb of petrol burn, hinder the back and treat 30 days to severe infections at private clinic's secret recipe, when coming my institute, 41 ℃ of T, BP12/8Kpa, P120 time/minute, HD6 gram, WBC14.6 * 10 ⁹/ I.Staring spells, bradykinesia, electrolyte disturbance, septicemia, tetanus symptom typical case.Wound surface is wrapped up with toilet paper, covers pus, skin injury about 25%.First visit: 1, burn and severe infections, skin injury 25%; 2, hemorrhagic anemia (miscarriage is lost blood before the burn); 3, septicemia; 4, tetanus; 5, electrolyte is seriously disorderly.Handle, debridement, infection is corrected anemia, tetanus treatment, supporting treatment.Wound surface external powder medicine for treating born and scald exposure method, hospitalization 199 days, not skin-grafting.The outside, lacquer joint, right side, mild scar, contracture, the activity of row lysis posterior joint is as usual, good springiness after other wound surface skin repair, cicatrix is not obvious.

Seven, contrast:

Contrast with the moist expose burn ointment that generally uses clinically at present: moist expose burn ointment is pretty good to the FFI wound surface curative effect of the second degree burn below 5%, and is undesirable with the wound surface effect that infects more than 10%.

With the second degree burn wound surface is benchmark, and medicine medication of the present invention was once cured in 10～15 days.The moist expose burn ointment twice-daily is coated with wound surface disunion in 15～20 days.The inventor has just accepted the 22 routine second degree burn wounded for medical treatment, uses powder medicine for treating born and scald of the present invention instead and cure after the moist expose burn ointment treatment needed skin-grafting more than 20 days, need not make skin graft.The present invention and moist expose burn ointment are used for same routine second degree burn patient, the right hand, forearm with the present invention once, wound surface exposes, and cures in 15 days.Left side forearm is coated with 0.5 cm thick outward with moist expose burn ointment, and sterile gauze wrapping day is changed dressings once, in the time of 15 days traumatic infection to 3-degree wound, after use the present invention instead and treated cicatrization 20 days." the medical officer people " 1996.4 (61), 151 Li Zhi armies of hospital of PLA etc. have reported that " moist expose burn ointment causes the right hand and infects 1 example " confirmed deep burn is failed to respond to any medical treatment, to the superficial burns easy infection.

Eight, demonstration

Powder medicine for treating born and scald has effects such as convergence, granulation promoting, coagulated protein, sterilization, infection.Be used for the burn and scald patient and make wound surface form airtight protective layer, control infection suppresses the bacillus pyocyaneus growth, prevents that septicemia from taking place.Powder medicine for treating born and scald can activate epithelial cell, promotes normal structure to form, and helps the wound surface immediate union.This medicine can be kept epithelial normal reparation, fibroblastic regeneration, epithelium formation, collagen is synthesized play an important role.Because pharmaceutical formulation is reasonable, some medicine can suppress cicatrix, so fibroblastic transition propagation and chaotic keloid propagation are had inhibition and mitigation.

This medicine is spent large-area burns and 30% with interior third degree burn effective percentage 100%, cure rate 100% through clinical verification to two below 60%.

Embodiment one: most preferred embodiment

5 parts of egg membranes, side uncle leaf 10, Folium Mori 10, the Radix Angelicae Dahuricae 10, Olibanum 10, Myrrha 10, Radix Sanguisorbae 10, Folium Ilicis Purpureae 10, Aloe 10, Borneolum Syntheticum 5, zinc sulfate 0.25

Embodiment two:

3 parts of egg membranes, side uncle leaf 8, Folium Mori 6, the Radix Angelicae Dahuricae 5, Olibanum 7, Myrrha 5, Radix Sanguisorbae 8, Folium Ilicis Purpureae 10, Aloe 6, Borneolum Syntheticum 3, zinc sulfate 0.3

Embodiment three:

1 part of egg membrane, side uncle leaf 5, Folium Mori 5, the Radix Angelicae Dahuricae 8, Olibanum 9, Myrrha 7, Radix Sanguisorbae 5, Folium Ilicis Purpureae 7, Aloe 5, Borneolum Syntheticum 1, zinc sulfate 0.25

Embodiment four:

4 parts of egg membranes, side uncle leaf 10, Folium Mori 8, the Radix Angelicae Dahuricae 6, Olibanum 5, Myrrha 5, Radix Sanguisorbae 7, Folium Ilicis Purpureae 5, Aloe 8, Borneolum Syntheticum 4, zinc sulfate 0.3

Embodiment five:

5 parts of egg membranes, side uncle leaf 5, Folium Mori 5, the Radix Angelicae Dahuricae 8, Olibanum 9, Myrrha 10, Radix Sanguisorbae 10, Folium Ilicis Purpureae 6, Aloe 10, Borneolum Syntheticum 1, zinc sulfate 0.25, catechu 6, Herba Centellae 10

Embodiment six:

1 part of egg membrane, side uncle leaf 8, Folium Mori 10, the Radix Angelicae Dahuricae 5, Olibanum 6, Myrrha 5, Radix Sanguisorbae 7, Folium Ilicis Purpureae 5, Aloe 8, Borneolum Syntheticum 2, zinc sulfate 0.3, catechu 8, Herba Centellae 5, Mirabilitum crystallina 6

Claims

1, a kind of powder medicine for treating born and scald is characterized in that it being that raw material by by following parts by weight is made:

2, powder medicine for treating born and scald according to claim 1 is characterized in that also comprising raw material: in catechu 5～10, Herba Centellae 5～10, the Mirabilitum crystallina 5～10 1～3 kind.

3, powder medicine for treating born and scald according to claim 1 is characterized in that being made by 5 parts of egg membranes, side uncle leaf 10, Folium Mori 10, the Radix Angelicae Dahuricae 10, Olibanum 10, Myrrha 10, Radix Sanguisorbae 10, Folium Ilicis Purpureae 10, Aloe 10, Borneolum Syntheticum 5, zinc sulfate 0.25.