CN107854554A - Yao nationality medicine externally applied ointment with strengthening the muscles and bones effect and preparation method thereof - Google Patents
Yao nationality medicine externally applied ointment with strengthening the muscles and bones effect and preparation method thereof Download PDFInfo
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- CN107854554A CN107854554A CN201711001417.XA CN201711001417A CN107854554A CN 107854554 A CN107854554 A CN 107854554A CN 201711001417 A CN201711001417 A CN 201711001417A CN 107854554 A CN107854554 A CN 107854554A
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- 230000000770 proinflammatory effect Effects 0.000 description 1
- APTZNLHMIGJTEW-UHFFFAOYSA-N pyraflufen-ethyl Chemical compound C1=C(Cl)C(OCC(=O)OCC)=CC(C=2C(=C(OC(F)F)N(C)N=2)Cl)=C1F APTZNLHMIGJTEW-UHFFFAOYSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 230000008925 spontaneous activity Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The invention discloses a kind of Yao nationality medicine externally applied ointment with strengthening the muscles and bones effect and preparation method thereof, it is made of the raw material including following compositions：Three money three, buffalo milk, Pterospermi Heterophylli, Giantleaf Ardisia Rhizome, shoulder plate return, Radix zanthoxyli, safflower, Radix Angelicae Sinensis, numb ancient customs, Chinese cassia tree, winding displacement grass, copper bore and lotus leaf, above-mentioned raw materials are proportionally matched, crush sterilization, the active drug composition in raw material is extracted by modern medicine method, externally used paste is made, this Yao nationality medicine externally applied ointment fills blood, dispelling wind and eliminating dampness, the effect of promoting blood circulation to remove blood stasis.Can set a broken bone pain in the back, treating swelling and pain by traumatic injury, arthralgia pain due to rheumatism, qi-deficiency kidney-deficiency, soreness of bones and muscles, the disease such as treating rheumatic ostealgia, arthritis, traumatic injury, fracture.
Description
Technical field
The present invention relates to a kind of externally applied ointment and preparation method thereof, externally applied ointment particularly with strengthening the muscles and bones effect and
Preparation method.
Background technology
For modern the elderly because the aging of body, physical function change, body is often in a kind of shape of inferior health
State.Pelvic bone pain, insufficiency of vital energy and blood, soreness of bones and muscles can usually be felt, it is easier to suffer from the diseases such as arthritis, rheumatism, rheumatoid.Year
Light people's usually body building, is also subjected to athletic injury, is pulled a muscle when serious during exercise, damages muscles and bones, or even cause bone
The major injuries such as folding.Develop as one pleases without conditioning and treatment with grieved such as above illness, extreme influence is good for human body
Health, cause serious sequelae.
It is varied with strengthening the muscles and bones, relaxing tendons and activating collaterals, the decoction of dispelling wind and eliminating dampness effect, medicament, paste on the market at present,
A feast for the eyes, effect is uneven.Wisdom crystallization of Yao nationality's Chinese medicine preparation as Yao nationality people, herbal medicine to Yao nationality's population collection
Long-term practice, works out really effective a variety of precious jade medicine compositions, the particularly disease such as strengthening the muscles and bones, traumatic injury, and precious jade medicine is even more to have
Its unique advantage.The present invention utilizes Yao nationality's conventional formulation, and the active drug composition in raw material is extracted by modern medicine method,
A kind of significant effect is made, easy to use, the Yao nationality medicine externally applied ointment for the strengthening the muscles and bones having no side effect.
We pass through patent and literature search, it has been found that some existing externally applied drugs on strengthening the muscles and bones effect, such as：
1st, Traditional Chinese plaster for bonesetting, application number：CN93100798.4；Applicant：Liu Guorong；
Summary：A kind of Chinese herbal medicine external application medical ointment --- Traditional Chinese plaster for bonesetting for treating fracture, it be by the root of bidentate achyranthes, broken benefit, the root of Dahurain angelica,
(forging) native copper, lycopodium calvatum, refute bone pin, rheum officinale, return the mixed of the third fine drug powder composition of tail, ground bettle, frankincense, myrrh, three money
Compound add proper honey, sesame oil or peanut oil etc vegetable oil hybrid modulation into body of paste.The ointment tool of the present invention
Have promoting blood circulation and removing blood stasis, make the effect of fracture blood fortune is abundant, growth of spur is fast and the effect for promoting union, it is equal to standby class fracture
Have a preferable therapeutic action, and with make, easy to use, the advantages that medicine source is enriched.
2nd, a kind of pharmaceutical composition for treating rheumatalgia pain, application number： CN201110382520.X；Applicant：Yao Yu
It is strong；
Summary：The present invention discloses a kind of pharmaceutical composition for treating rheumatalgia pain, and said composition is by monkshood, resina liquidamberis, radix scutellariae, half
Maple lotus, bark of ash, Radix Aconiti Kongboensis, rhizoma cibotii, notopterygium root, vomiting nut, psoralea corylifolia, rhizoma Gastrodiae, akebi, safflower, ramulus mori, tripterygium wilfordii, Radix Angelicae Sinensis,
Berba aristolochiae mollissimae, Fructus Corni, reticulate millettia and radix cyathulae composition.Pharmaceutical composition of the present invention adds customary adjuvant according to common process and is made
Capsule, tablet, pill, granule, oral liquid, emplastrum, ointment, spray, liniment or the tincture that clinic receives.This hair
Bright pharmaceutical composition has the effect of nourishing disney and strengthening bone, blood-activating analgetic, dispelling wind and removing obstruction in the meridians.Treatment rheumatism, rheumatoid arthritis are drawn
The pain significant effect risen, has no toxic side effect.
3rd, a kind of strengthening the muscles and bones ointment, application number：CN201510645190.7；Apply for (patent right) people：Qingdao jade-like stone brightness reaches
Logical Chemical Industry Science Co., Ltd；
Summary：The present invention relates to Chinese medicine technical field, specifically a kind of strengthening the muscles and bones ointment.It includes following mass component
Composition：Safflower 3-5 parts, cortex acanthopanacis 8-12 parts, Ramulus Taxilli 8-12 parts, Radix Angelicae Sinensis 8-12 parts, reticulate millettia 1-3 parts, rhizoma cibotii 2-4 parts,
Rhizoma homalonemae 3-8 parts, eupolyphage sece steleophaga 2-4 parts, lanatechead saussurea herb with flower 3-8 parts, pyrola 8-12 parts, piece of antler 1-3 parts, folium photiniae 3-8 parts, deer's sinew
15-20 parts, pseudo-ginseng 8-12 parts, root of bidentate achyranthes 8-12 parts, bark of eucommia 2-4 parts, Animal Bone 65-80 parts, borneol 8-12 parts, Pheretima 8-12
Part, dragon's blood 2-3 parts, Moschus 3-8 parts.The ointment of strengthening the muscles and bones provided by the invention, by Cutaneous permeation in ill depths, play
It is swelling and pain relieving, promoting blood circulation and removing blood stasis, be free from side effects, for traumatic injury, limb swelling pain, to synthetism, osteoproliferation, waist it is de- and
Spur etc. has good therapeutic effect.
Above externally applied ointment also has strengthening the muscles and bones effect, but composition is different from the present invention, therefore also can in therapeutic effect
There is difference.
The content of the invention
The purpose of the present invention is to provide one kind to market to be different from existing external application Chinese medicine, can be filled blood, dispelling wind and eliminating dampness is living
Blood dissipates the effect of stasis of blood.Can set a broken bone pain in the back, treating swelling and pain by traumatic injury, arthralgia pain due to rheumatism, soreness of bones and muscles, treating rheumatic ostealgia, arthritis, bruise damage
The diseases such as wound, fracture.
To achieve these goals, the technical scheme is that：
Yao nationality medicine externally applied ointment with strengthening the muscles and bones effect, it is characterised in that：It is made of the raw material including following compositions：
The 14-16 parts of three money three, buffalo milk 2-3 parts, Pterospermi Heterophylli 14-16 parts, Giantleaf Ardisia Rhizome 4-6 parts, shoulder plate return 2-3 parts, Radix zanthoxyli 4-6 parts,
Safflower 8-11 parts, Radix Angelicae Sinensis 8-11 parts, numb ancient customs 8-11 parts, Chinese cassia tree 8-11 parts, winding displacement grass 4-6 parts, copper bore 2-3 parts, lotus leaf 2-3
Part.
The present invention external plaster application agent preparation method be：
The 14-16 parts of three money three, buffalo milk 2-3 parts are taken by weight ratio, Pterospermi Heterophylli 14-16 parts, Giantleaf Ardisia Rhizome 4-6 parts, are shouldered plate and are returned 2-3
Part, Radix zanthoxyli 4-6 parts, safflower 8-11 parts, Radix Angelicae Sinensis 8-11 parts, numb ancient customs 8-11 parts, Chinese cassia tree 8-11 parts, winding displacement grass 4-6 parts, copper bore
2-3 parts, lotus leaf 2-3 parts, and raw material is pulverized and mixed, it is placed in microwave dryer and is dried and sterilizes；Raw material adds 10-15 times
Water heating is boiled 1-2 hours, is filtered, and the dregs of a decoction add 5-10 times to measure water to boil again 0.5-1 hours again, is filtered, and decoction is merged and dense
The concentrate that 60 DEG C of relative densities are 1.2-1.25 is reduced to, cooling, retains filtrate A；Filtering gained the dregs of a decoction add 3-6 times measure 95%
Ethanol, 4-8 DEG C of standing 6-48 hour is put in after stirring, filtering, filtrate is put into heating recovery ethanol in ethanol recycling can and obtained
Decoction cooling after refilter, and be concentrated into 60 DEG C of relative densities be 1.2-1.25 concentrate, retain liquor B；By filtrate A and
Liquor B is mixed, then medicine liquid heating is concentrated into paste, is added transdermal promotion absorbent stirring, pressure sensitive adhesive, is produced externally applied plaster
Agent.
The present invention externally used paste preparation method be：
The 14-16 parts of three money three, buffalo milk 2-3 parts are taken by weight ratio, Pterospermi Heterophylli 14-16 parts, Giantleaf Ardisia Rhizome 4-6 parts, are shouldered plate and are returned 2-3
Part, Radix zanthoxyli 4-6 parts, safflower 8-11 parts, Radix Angelicae Sinensis 8-11 parts, numb ancient customs 8-11 parts, Chinese cassia tree 8-11 parts, winding displacement grass 4-6 parts, copper bore
2-3 parts, lotus leaf 2-3 parts, and raw material is pulverized and mixed, it is placed in microwave dryer and is dried and sterilizes；Raw material adds 10-15 times
Water heating is boiled 1-2 hours, is filtered, and the dregs of a decoction add 5-10 times to measure water to boil again 0.5-1 hours again, is filtered, and decoction is merged and dense
The concentrate that 60 DEG C of relative densities are 1.2-1.25 is reduced to, cooling, retains filtrate A；Filtering gained the dregs of a decoction add 3-6 times measure 95%
Ethanol, 4-8 DEG C of standing 6-48 hour is put in after stirring, filtering, filtrate is put into heating recovery ethanol in ethanol recycling can and obtained
Decoction cooling after refilter, and be concentrated into 60 DEG C of relative densities be 1.2-1.25 concentrate, retain liquor B；By filtrate A and
Liquor B is mixed, then medicine liquid heating is concentrated into paste, and the transdermal promotion absorbent of addition, medical ventolin stir, produced outer
Use paste.
Medically research shows that the herbal component selected by the present invention has following effect：
Above-described three money three, pulse family Ormosia plant rosewood, is used as medicine with root, root skin, stem and leaf,【Classification system】
OrmosiahenryiPrain,【Alias】：Green bamboo snake, cow dung firewood,【Meridian distribution of property and flavor】：Acrid flavour, warm-natured, poisonous, returns spleen warp,【Work(
It can cure mainly】：Dispelling wind and eliminating dampness, promoting blood circulation to remove blood stasis, narcotic analgesic, rheumatic arthritis, bone fracture pain in the back, fracture, acute sprain can be treated.
Tradition application：Flower：Dispelling wind and eliminating dampness, scattered stasis pain.For arthralgia pain due to rheumatism, traumatic injury.Root：Dispelling wind stopping cough, blood stasis removing analgesic.For
Arthralgia pain due to rheumatism, traumatic injury, neuralgia.Fruit：For traumatic injury, rheumatic arthritis.There is an open source literature expression, in flower and fruit
The Multiple components such as Rhomotoxin there is analgesia and sedation effect well.Root mainly contains flavone compound and andromedotoxin I,
Both of which has certain anti-inflammatory activity, therefore root has obvious antiinflammatory action, immunosuppressive action and slight refrigeration function.
Just because of these anti-inflammatory and analgesic effects, therefore it is widely used in orthopaedics.
Above-described milk tree, be moraceae plants Ficus hispida root, skin, leaf,【Classification system】Ficus hispida
L.f.,【Alias】：Milk is numb, milk is harvested, pig mother tea, pig milk tree, cow's milk medicine, big milk, more Nuo Shu, harvests water wax gourd, car pusher
Entering stone, milk is public to be set,【Meridian distribution of property and flavor】：Sweet, slight bitter, cool in nature, returns spleen, lung, large intestine channel,【Major function】：Wind and heat dispersing, disappear
Product resolving sputum, invigorating the spleen dehumidifying, scattered stasis.Cure mainly lukorrhagia due to hypofunction of the spleen, treating swelling and pain by traumatic injury, arthralgia pain due to rheumatism.
Above-described Pterospermi Heterophylli, be Sterculiaceae plant pterospermum heterophyllum Hance root or stem branch,【Classification system】
Pterospermum heterophyllum hance,【Alias】：Velutinous cinquefoil root tree, negative and positive leaf,【Meridian distribution of property and flavor】：It is sweet, it is warm-natured,
【Major function】：Wind-damp dispelling, relaxing tendons and activating collaterals.Cure mainly rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lumbocrural pain,
Hemiplegia, traumatic injury, bruise；Bleeding on knife is controlled in external application.The effect of Pterospermi Heterophylli maximum is exactly that dispelling wind and eliminating dampness and relaxing muscles and tendons are lived
Blood, also there is certain therapeutic efficiency to painful swelling of joints.Usually it is being used for rheumatic disease and arthritis and psoas is powerless etc.
With the symptom such as hemiplegia, also there is obvious effect with traumatism and bleeding to spraining.30 ~ 60 grams of dosage, decoction or infusing drugs in wine.With controlling
Wind-cold-dampness arthralgia, rheumatic flaccidity, lumbar muscle strain, paralysis of the limbs, postpartum paralysis, joint joint stuffiness, traumatic injury swelling and pain.
Above-described Giantleaf Ardisia Rhizome, this product are the dry root of Myrsinacea plant Giantleaf Ardisia Rhizome,【Classification system】Ardisia
Gigantifolia stapf,【Alias】：Big dispensing, laciniate blumea herb, mountain mouse, blood maple, mountain pig medicine,【Meridian distribution of property and flavor】：Acrid flavour, property
Temperature, enter liver, spleen, kidney channel,【Major function】：Wind-dispelling breathes, swelling and pain relieving.Root：For rheumatic arthritis, pain in waist and lower extremities, bruise
Swelling and pain；Leaf：Strain, carbuncle furuncle poison, chronic ulcer are controlled in external application.Wind-damp dispelling, strengthen the bone, promoting blood circulation.Rheumatism arthralgia and myalgia is controlled, is fallen
Beat damage, postpartum blood stasis, ulcer ulcer.
Above-described plate of shouldering is returned, the dry aerial parts of polygonaceae plant polygonum perfoliatum,【Classification system】 Polygonum
Perfoliatum L,【Alias】：Colter thorn rattan, tiger profit, tripterygium wilfordii, thunderbolt wood, side's victory plate, golden hook, flatiron are careless, projecting
Zijin hook, the white grass in river, plough point grass, include careless, the imperial celestial grass of rake, fish tail flower, thorn colter, snake only, it is anxious change rope, TUIXUECAO, brave tongue grass,
There are Jin viola japonicas, pierce wintercherry, block snake wind, spinosity Long Stephania Herb, colter rattan, triangle vine, Herba Lespedezae Cuneatae, have Jin live charcoal rattan, big grasshopper pin, five
Poisonous weeds, fire wheel arrow, ram's horn thorn, She Yacao, Herba Polygoni Perfoliati, tiger thorn, the public thorn of cat, white crow acid, polygonum perfoliatum, dried bean curd greatly be careless, sour rattan,
Half-capitate hemiboea herb, snake see move back, water Ma Ling, bud-leaf knotweed, spinosity colter rattan, snake sting grass, cochinchina passionflower herb, string heart grass,【Meridian distribution of property and flavor】：Sour,
Hardship, mild-natured, return lung, small intestinl channel,【Major function】：It is clearing heat and detoxicating, inducing diuresis and reducing edema, dissipate stasis of blood hemostasis.Treating swelling and pain by traumatic injury is cured mainly, plate is shouldered and returns
Gelatin fiber is known as anastalsis.Control the inferior the fresh plate of shouldering of limb painful swelling of joints and return 60~90g of herb.It is decocted in water for oral dose.(《Fujian Chinese herbal medicine》)
Above-described Radix zanthoxyli, it is the dry root of rutaceae Radix zanthoxyli,【Classification system】Zanthorμlum nitidum
(Roxb.) DC.,【Alias】：Shinyleaf pricklyash root, two-sided thorn, Chinese pepper, tiger of going down the hill,【Meridian distribution of property and flavor】：Bitter, pungent, mild-natured, Return liver, stomach
Through,【Major function】：It is promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, dispelling wind and removing obstruction in the meridians, removing toxicity for detumescence.Cure mainly injury from falling down, arthralgia pain due to rheumatism, poisonous snake
Bite；Externally treating burns and scalds.Because contained composition crystallization -8 has analgesic activity, anodyne can be used as, for surface anesthesia, office
Anaesthetize in portion.
Above-described safflower, it is that drying for feverfew safflower is spent,【Classification system】Carthamus tinctorius
L.,【Alias】：Safflower,【Meridian distribution of property and flavor】：Acrid flavour, warm-natured, the thoughts of returning home, Liver Channel,【Major function】：Fill blood, invigorate blood circulation, dissipate
The stasis of blood relieves pain.Cure mainly injury from falling down, sore swell and ache curative.Safflower oil contains very high unrighted acid, and its linoleic acid content is up to 70-
80%, there is preferable health-care effect to cardiovascular system of human body.
Above-described Radix Angelicae Sinensis, the root of umbelliferae angelica,【Classification system】Angelica sinensis,【Alias】：
It is dry return, horse hair Radix Angelicae Sinensis, the Qin is returned, horse hair is returned, cloud is returned, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis,【Meridian distribution of property and flavor】：Bitter, temperature, it is nontoxic, Return liver, the heart,
The spleen channel,【Major function】：Enrich blood, invigorate blood circulation, cure mainly injury from falling down, muscle arthrosis pain.Radix Angelicae Sinensis is to anxious caused by a variety of proinflammatory agents
Capillary permeability increases property, tissue edema and chronic injury significantly inhibit effect, and can suppress inflammation later stage granulation
Hyperblastosis, but the weight of adrenal gland and thymus gland is not influenceed, its antiinflammatory action is prompted independent of hypophysis-adrenal system.When
Water extract is returned to show analgesic activity to writhing response caused by intraperitoneal injection acetic acid, its analgesic activity intensity is acetyl salicylic
1.7 times of sour sodium.External application can accelerate rabbit ear wound healing, infiltrate contrafluxion, leucocyte and fiber, newborn epithelium regeneration,
There is hemostasis to local organization and strengthen peripheral circulation effect.Illustrate that Radix Angelicae Sinensis has antibacterial, antiinflammation.
Above-described boon wind, it is used as medicine for the cauline leaf or root of gnetaceae plant,【Classification system】Gnetum
Montanum Markgr,【Alias】：Sweetberry jointfir, sub- rattan, Wu Gufeng are bought,【Meridian distribution of property and flavor】：Bitter, it is warm-natured,【Major function】：
Dispelling wind and eliminating dampness, promoting blood circulation to remove blood stasis, tonneau grain, arthralgia pain due to rheumatism, the arthroncus of knee, traumatic injury are cured mainly, numb limb is powerless, sprains, frustrates
Wound, fracture, pain in waist and lower extremities, arthralgia, soreness of bones and muscles.《Luchuan book on Chinese herbal medicine》：Cauline leaf：Continuous muscles and bones, traumatic injury is controlled, the injury of tendon and muscle of fracturing.《Extensively
Western medicine plants register》：Cauline leaf：Synthetism, subside a swelling, analgesic.Control treating rheumatic ostealgia.Root：Control the arthroncus of knee.
Above-described Chinese cassia tree, dry hide and thick branch skin for Lauraceae aiphyllium plant Chinese cassia tree,【Classification system】
Cinnamomum cassia Presl,【Alias】：Male osmanthus, purple osmanthus, great Gui,【Meridian distribution of property and flavor】：Acrid flavour, sweet, extremely hot in nature, return kidney,
Spleen, the heart, Liver Channel,【Major function】：There is a mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, the effect of warming meridian.Cure mainly impotence palace
It is cold, waist and knee crymodynia, deficiency of the kidney and dyspnea, deficient yang with upper manifestation, dizziness hot eyes, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea.《Japan hanako materia medica》：Control all
General mood, general debility is mended, lead to nine orifices, sharp joint, strengthening the essence, improving eyesight, warm up waist and knee, break Xuan addiction abdominal mass, dispersing blood stasis blood, control wandering arthritis joint contraction
Contracting, continuous muscles and bones, myogenic meat.Chilly, limb for the insufficiency of the kidney yang are cold, waist and knee crymodynia, also the empty asthma available for the failure of the kidney in receiving air, gas
It is inverse；The cinnaldehydrum contained in Chinese cassia tree has obvious sedation to mouse, shows as spontaneous activity reduction, resists crystal methamphetamine
（Methamphetamine）Ataxia and extension ciclobarbital soluble caused by caused multi-activity excessively, rotating stick test
Anesthesia duration etc..Application mouse pressure anal spine swashs or the method for intraperitoneal injection acetic acid observation writhing motion proves that it has analgesia to make
With.
Above-described winding displacement grass, the aerial part for being pulse family Phyllodium rows of plants Qian Shu,【Classification system】
Phyllodium pulchellum (L.) Desv.,【Alias】：Imperial squama grass, period of the day from 11 a.m. to 1 p.m conjunction, desmodium, period of the day from 11 a.m. to 1 p.m spirit, folded money grass, money
Lysimachia sikokiana, double money, leopard, cash strings are careless, double money, paper money sword,【Meridian distribution of property and flavor】：It is lightly seasoned；It is puckery；It is cool in nature；Mild toxicity, spleen, Liver Channel,
【Major function】：Clearing away heat and promoting diuresis, Hua Yu Xiao wei, dispelling wind and eliminating dampness, promoting blood circulation to remove blood stasis.Tradition application：Control treating rheumatic ostealgia, arthritis, fall
Beat damage, fracture.
Above-described copper bores, the dry root and rattan of rattan of being felt relieved for Icacinaceae plant,【Classification system】Mappianthus
Iodoides Hand._Mazz,【Alias】：Elopichthys bambusa, jute bone wind, Huang Jiuniu, hesperidium rattan, false ergcibe obtusifolia,【Meridian distribution of property and flavor】：Property
It is flat, sweet, it is light,【Major function】：Arthralgia pain due to rheumatism, traumatic injury, swelling and pain relieving, fracture, limbs joint red and swollen heat pain.
Above-described lotus leaf, it is the leaf of nymphaeaceae plant lotus,【Classification system】FoliumNelumbinis【Alias】：Lotus
Leaf, lotus root leaf,【Meridian distribution of property and flavor】：Bitter, mild-natured, Return liver, spleen, stomach,【Major function】：Clearing away summer-heat and eliminating dampness, sending up the lucid yang, cool blood are stopped
Blood.Burnt FOLIUM NELUMBINIS then has the function of inducing astrigency removing blood stasis and hemostasis.Hot summer weather polydipsia is cured mainly, summer heat damp diarrhea, splenasthenic diarrhea, blood-head tells nosebleed, is had blood in stool
Uterine bleeding, also there is hemostasis.
The pharmacological function with each composition in the Yao nationality medicine externally applied ointment with strengthening the muscles and bones effect of the invention is：
In its prescription, the dispelling wind and eliminating dampness of three money three, promoting blood circulation to remove blood stasis, narcotic analgesic, rheumatic arthritis, bone fracture pain in the back, bone can be treated
Folding, acute sprain, ease pain well, calm, anti-inflammatory effects；Pterospermi Heterophylli dispelling wind and eliminating dampness and relaxing tendons and activating collaterals, also have to painful swelling of joints
Certain therapeutic efficiency, both are monarch drug in a prescription
Safflower, Radix Angelicae Sinensis inrigorating qi and promoting blood circulation, invigorate blood circulation, blood stasis removing analgesic, externally hindering when merger has antibacterial, antiinflammation.Boon wind is dispelled
Wind dehumidifies, promoting blood circulation to remove blood stasis, tonneau grain, to spraining, dampens, fracture is effective in cure；Chinese cassia tree mends fire supporing yang, guiding fire to origin, tonifying spleen kidney,
And have sedation and analgesia effect, four be ministerial drug；
Giantleaf Ardisia Rhizome wind-damp dispelling, strengthens the bone, promoting blood circulation；Radix zanthoxyli is promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain；Winding displacement grass Yu Xiao wei, wind-dispelling
Dehumidifying, promoting blood circulation to remove blood stasis, can control treating rheumatic ostealgia, arthritis, traumatic injury, fracture；Shoulder plate and return inducing diuresis and reducing edema, dissipate stasis of blood hemostasis；Copper bores
Swelling and pain relieving；Milk tree wind and heat dispersing, disperse accumulations resolving sputum, invigorating the spleen dehumidifying, scattered stasis；Four be adjutant；
Lotus leaf clearing away summer-heat and eliminating dampness, also have hemostasis act as make medicine.
More than be exactly the Yao nationality medicine externally applied ointment and preparation method thereof of the present invention with strengthening the muscles and bones effect, production process flow
Simply, maximize to retain and is filled blood in various raw materials, dispelling wind and eliminating dampness, the effect of promoting blood circulation to remove blood stasis.Can set a broken bone pain in the back, bruise swell
Bitterly, the disease such as arthralgia pain due to rheumatism, soreness of bones and muscles, qi-deficiency kidney-deficiency, treating rheumatic ostealgia, arthritis, traumatic injury, fracture.
Beneficial effects of the present invention：
1st, the present invention is by the refined purpose for forming, treatment strengthening the muscles and bones being reached using Chinese herbal medicine itself effect of Yao nationality's ancient prescription, this hair
It is bright applied widely, men and women, old and young effective in cure to diseases such as rheumatism, rheumatoid, arthritis, qi-deficiency kidney-deficiency, traumatic injury, fracture
Patient is applicable.
2nd, this externally applied ointment raw material are widely present and cheap, and suitable pharmaceutical factory large-scale production needs.
3rd, this externally applied ointment patient is applicable convenient, and medicine has no side effect without pre-treatment, plug and play.
Embodiment
Embodiment 1
Take following raw material：3 14 parts of three money, 2 parts of buffalo milk are taken by weight ratio, 14 parts of Pterospermi Heterophylli, 4 parts of Giantleaf Ardisia Rhizome, are shouldered plate and are returned 2
Part, 4 parts of Radix zanthoxyli, 8 parts of safflower, 8 parts of Radix Angelicae Sinensis, 8 parts of numb ancient customs, 8 parts of Chinese cassia tree, 4 parts of winding displacement grass, copper bore 2 parts, 2 parts of lotus leaf, and will
Raw material is pulverized and mixed, and is placed in microwave dryer and is dried and sterilizes;Raw material adds 10 times of water heating to boil 1 hour, filters, the dregs of a decoction
Again plus 5 times of amount water boil 0.5 hour again, filter, decoction is combined and concentrated into the concentrate that 60 DEG C of relative densities are 1.2, cooled down,
Retain filtrate A；The filtering gained dregs of a decoction add 95% ethanol of 3 times of amounts, and 4 DEG C are put in after stirring and stands 6 hours, filtering, filtrate is put into second
Refiltered after the decoction cooling that heating recovery ethanol obtains in alcohol recycling can, and be concentrated into the concentration that 60 DEG C of relative densities are 1.2
Liquid, retain liquor B；Filtrate A and liquor B are mixed, then medicine liquid heating is concentrated into paste, transdermal promotion absorbent is added and stirs
Mix, pressure sensitive adhesive, produce external plaster application agent.
Embodiment 2
Take following raw material：3 16 parts of three money, 3 parts of buffalo milk are taken by weight ratio, 16 parts of Pterospermi Heterophylli, 6 parts of Giantleaf Ardisia Rhizome, are shouldered plate and are returned 3
Part, 6 parts of Radix zanthoxyli, 11 parts of safflower, 11 parts of Radix Angelicae Sinensis, 11 parts of numb ancient customs, 11 parts of Chinese cassia tree, 6 parts of winding displacement grass, copper bore 3 parts, 3 parts of lotus leaf,
And be pulverized and mixed raw material, it is placed in microwave dryer and is dried and sterilizes.Raw material adds 15 times of water heating to boil 2 hours, filters,
The dregs of a decoction add 10 times of amount water to boil again 1 hour again, filter, and decoction is combined and concentrated into the concentrate that 60 DEG C of relative densities are 1.25,
Cooling, retain filtrate A；The second step filtering gained dregs of a decoction add 95% ethanol of 6 times of amounts, and 8 DEG C are put in after stirring and stands 48 hours, mistake
Filter, refiltered after filtrate is put into the cooling of heating recovery ethanol obtains in ethanol recycling can decoction, and be concentrated into 60 DEG C it is relatively close
The concentrate for 1.25 is spent, retains liquor B, filtrate A and liquor B are mixed, then medicine liquid heating is concentrated into paste, is added transdermal
Promote absorbent, medical ventolin to stir, produce externally used paste.
Embodiment 3
Take following raw material：3 15 parts of three money, 2 parts of buffalo milk are taken by weight ratio, 15 parts of Pterospermi Heterophylli, 5 parts of Giantleaf Ardisia Rhizome, are shouldered plate and are returned 3
Part, 5 parts of Radix zanthoxyli, 9 parts of safflower, 9 parts of Radix Angelicae Sinensis, 8 parts of numb ancient customs, 10 parts of Chinese cassia tree, 5 parts of winding displacement grass, copper bore 3 parts, 3 parts of lotus leaf, and
Raw material is pulverized and mixed, microwave dryer is placed in and is dried and sterilizes.Raw material adds 12 times of water heating to boil 2 hours, filters, medicine
Slag adds 10 times of amount water to boil again 0.5 hour again, filters, and decoction is combined and concentrated into the concentrate that 60 DEG C of relative densities are 1.25,
Cooling, retain filtrate A；The second step filtering gained dregs of a decoction add 95% ethanol of 5 times of amounts, and 8 DEG C are put in after stirring and stands 24 hours, mistake
Filter, refiltered after filtrate is put into the cooling of heating recovery ethanol obtains in ethanol recycling can decoction, and be concentrated into 60 DEG C it is relatively close
The concentrate for 1.22 is spent, retains liquor B, filtrate A and liquor B are mixed, then medicine liquid heating is concentrated into paste, is added transdermal
Promote absorbent, medical ventolin to stir, produce externally used paste.
Application Example：
Clinic carries out this precious jade medicine externally applied ointment to totally 159 patients and is treated and be tracked further consultation, and the age is 17 years old to 63
Year, wherein patient are included with Types Below：1st, qi-deficiency kidney-deficiency patient；2nd, rheumatism, rheumatoid arthritis patients；3rd, traumatic injury is suffered from
Person.
Efficacy assessment standard：
Recovery from illness：Symptom disappears, painless, no weak sense.
Effectively：Symptom degree mitigates, and pain mitigates.
It is invalid：Symptom has no obvious change.
Therapeutic scheme：
Patient by external plaster or is applied to affected part daily, and it is more than hour to continue 16, and it is a course for the treatment of to be used continuously 10, it
Further consultation observation once, obtains following clinical data afterwards：
| Before treatment | After treatment | It is efficient | Cure rate | Use embodiment |
| Qi-deficiency kidney-deficiency patient 24 | Invalid 3；Effective 15；Recovery from illness 6 | 87.5% | 25% | Embodiment 1 |
| Qi-deficiency kidney-deficiency patient 26 | Invalid 2；Effective 19；Recovery from illness 5 | 92.3% | 19.2% | Embodiment 2 |
| Rheumatism, rheumatoid arthritis patients 27 | Invalid 0；Effective 14；Recovery from illness 13 | 100% | 48.1% | Embodiment 1 |
| Rheumatism, rheumatoid arthritis patients 28 | Invalid 1；Effective 16；Recovery from illness 11 | 96.4% | 39.3% | Embodiment 2 |
| Traumatic injury patient 33 | Invalid 5；Effective 20；Recovery from illness 8 | 84.8% | 24.2% | Embodiment 1 |
| Traumatic injury patient 33 | Invalid 6；Effective 17；Recovery from illness 10 | 81.8% | 30.3% | Embodiment 2 |
Clinical test shows：The present invention has the Yao nationality medicine externally applied ointment of strengthening the muscles and bones effect to qi-deficiency kidney-deficiency patient；Rheumatism, class wind
Wet arthritic；Traumatic injury patient is effective in cure, and best to rheumatism, rheumatoid arthritis, and effective percentage almost reaches
To 100%.
Embodiment 1：Lu, man, people from Guangxi Hechi, 35 years old, readme was had a sleepless night, is dizzy, having a pain in the back, lower limb are weak,
It is insufficiency of vital energy and blood to go to hospital's tcm diagnosis, deficiency of the kidney, afterwards using the external plaster application agent of the embodiment of the present invention 1 be affixed on navel lower section and
At waist, about 16 hours of topical application of drug time are total to daily, 10 evenings have been used continuously.Insomnia is felt, dizzy symptom disappears,
Pain in back and loin disappears, leg response force.
Embodiment 2：Huang, female, people from Liuzhou, 58 years old, the normal swelling and pain of the double knees of readme, especially rainy weather were more
Very.It is knee rheumatoid arthritis toward hospital diagnosis.The daily ointment of the embodiment of the present invention 2 of smearing is daily to apply three times in affected part,
After being used continuously 10.Double knee pain be improved significantly, be continuing with to after 30 days, symptom is wholly absent.
Embodiment 3：Zhang, man, Guangxi Gold show people, left foot sprain of ankle in being moved before 21 years old, 1 year, recurred in 1 year twice,
It is laceration of ligament through examination in hospital as old complaint.Zhang is applied at left ankle using the ointment of the embodiment of the present invention 2 daily, daily
Three times, having used 20, during which do not taken exercises in resting the stage, patient pain disappears after 20 days, and can take exercises, after
Have no grieved recurrence.
Claims (3)
- A kind of 1. Yao nationality medicine externally applied ointment with strengthening the muscles and bones effect, it is characterised in that：It is former by the Chinese herbal medicine of following weight proportion Material is made：The 14-16 parts of three money three, buffalo milk 2-3 parts, Pterospermi Heterophylli 14-16 parts, Giantleaf Ardisia Rhizome 4-6 parts, shoulder plate and return 2-3 parts, Radix zanthoxyli 4-6 parts, safflower 8-11 parts, Radix Angelicae Sinensis 8-11 parts, numb ancient customs 8-11 parts, Chinese cassia tree 8-11 parts, winding displacement grass 4-6 parts, copper bore 2-3 parts, lotus Leaf 2-3 parts；Obtained external medicine preparation is external plaster application agent, externally used paste.
- 2. there is the Yao nationality medicine externally applied ointment of strengthening the muscles and bones effect as claimed in claim 1, it is characterised in that：It is prepared by external plaster application agent Process is as follows：The first step, take by weight ratio three money three, buffalo milk, Pterospermi Heterophylli, Giantleaf Ardisia Rhizome, shoulder plate return, Radix zanthoxyli, safflower, Radix Angelicae Sinensis, fiber crops Ancient customs, Chinese cassia tree, winding displacement grass, copper brill and lotus leaf, and raw material is pulverized and mixed, it is placed in microwave dryer and is dried and sterilizes；Second step, raw material add the heating of 10-15 times of water to boil 1-2 hours, filtered, and the dregs of a decoction add 5-10 times to measure water to boil 0.5- again again 1 hour, filtering, decoction is combined and concentrated to the concentrate that 60 DEG C of relative densities are 1.2-1.25, cooling, retains filtrate A；3rd step, the second step filtering gained dregs of a decoction add 3-6 times of 95% ethanol measured, it is small that 4-8 DEG C of standing 6-48 are put in after stirring When, filtering, refiltered after filtrate is put into the decoction cooling that heating recovery ethanol obtains in ethanol recycling can, and be concentrated into 60 DEG C of phases To the concentrate that density is 1.2-1.25, retain liquor B；4th step, filtrate A and liquor B are mixed, then medicine liquid heating is concentrated into paste, are added transdermal promotion absorbent and are stirred Mix, pressure sensitive adhesive, produce external plaster application agent.
- 3. there is the Yao nationality medicine externally applied ointment of strengthening the muscles and bones effect as claimed in claim 1, it is characterised in that：It is prepared by externally used paste Process is as follows：The first step, take by weight ratio three money three, buffalo milk, Pterospermi Heterophylli, Giantleaf Ardisia Rhizome, shoulder plate return, Radix zanthoxyli, safflower, Radix Angelicae Sinensis, fiber crops Ancient customs, Chinese cassia tree, winding displacement grass, copper brill and lotus leaf, and raw material is pulverized and mixed, it is placed in microwave dryer and is dried and sterilizes；Second step, raw material add the heating of 10-15 times of water to boil 1-2 hours, filtered, and the dregs of a decoction add 5-10 times to measure water to boil 0.5- again again 1 hour, filtering, decoction is combined and concentrated to the concentrate that 60 DEG C of relative densities are 1.2-1.25, cooling, retains filtrate A；3rd step, the second step filtering gained dregs of a decoction add 3-6 times of 95% ethanol measured, it is small that 4-8 DEG C of standing 6-48 are put in after stirring When, filtering, refiltered after filtrate is put into the decoction cooling that heating recovery ethanol obtains in ethanol recycling can, and be concentrated into 60 DEG C of phases To the concentrate that density is 1.2-1.25, retain liquor B；4th step, filtrate A and liquor B are mixed, then medicine liquid heating is concentrated into paste, add transdermal promotion absorbent, medical Vaseline stirs, and produces externally used paste.
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