CN107737074A

CN107737074A - A kind of oral nursing liquid for clearing up tartar

Info

Publication number: CN107737074A
Application number: CN201711212548.2A
Authority: CN
Inventors: 李妍
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-11-28
Filing date: 2017-11-28
Publication date: 2018-02-27

Abstract

The invention discloses a kind of oral nursing liquid for clearing up tartar, including following aspect：It is process by compositions such as gardenia, orchid, wintersweet, Herba Andrographitis, honeysuckles, including following methods（1）Flower liquid extraction, gardenia, orchid, wintersweet are placed on distillation layer circulation boiling, rear efflorescence is drained and adds water by fermentation；（2）Prepared by medicament, Herba Andrographitis, honeysuckle, Canton love-pea vine and folium artemisiae argyi are submerged initially in acetic acid and soaked, and efflorescence is cleaned after taking-up and adds water and enzyme agent, is digested and boiling；（3）Extract powder, it is put into frying pan and is fried to slight burnt odor after Radix Isatidis and calamus are crushed, add absolute ethyl alcohol refluxing extraction；（4）Mixing, remove ionized water and add bamboo salt and sodium carbonate, heating adds trilliaceae extract, Changnienia amoena extract, mixing flower extract solution, medicament powder A, medicament powder B, is incubated after being stirred；（5）It is filling, first conditioning liquid processed is sterilized using ultraviolet light, then bottled rear obtained oral nursing liquid.

Description

A kind of oral nursing liquid for clearing up tartar

Technical field

The invention belongs to oral nursing liquid processing technique field, and in particular to a kind of oral nursing liquid for clearing up tartar.

Background technology

Tartar, also known as bacterial plaque, the biological film quality in corona, neck and tooth seam is deposited in for long duration of action, its Mainly by being formed after the petrochemical industry such as swill, dead epithelial cell, bacterium；Contain substantial amounts of streptococcus and a variety of anaerobism in tartar Strain, it, which carries out anaerobic effect generation acidic materials, can corrode the formation of enamel promotion carious tooth, while can also stimulate gum to lead Cause the periodontal diseases such as periodontitis, gingivitis to occur, larger infringement can be caused to dental health.Pass through daily toothpaste method for brushing teeth Newly formed softer, thin tartar can be purged, but be difficult to clearly for the tartar between established tartar and slot Reason, still can be damaged to dental health；And toothwash method is used, long time integration can remove by mechanical rubbing method Tartar composition, but dental surface enamel can also be damaged simultaneously, the service life of tooth can be reduced；Traditional oral cavity shield Reason liquid can only play a part of clearing up oral cavity and pure and fresh oral cavity, and the oral nursing liquid with cleaning tartar effect still belongs in the market Blank.To solve the above problems, the invention provides a kind of oral nursing liquid for clearing up tartar.

The content of the invention

The present invention is directed to the problem of existing：Method for brushing teeth is difficult to clearly for the tartar between established tartar and slot Reason, still can be damaged to dental health；And toothwash method is used, long time integration can remove by mechanical rubbing method Tartar composition, but dental surface enamel can also be damaged simultaneously, the service life of tooth can be reduced；Traditional oral cavity shield Reason liquid can only play a part of clearing up oral cavity and pure and fresh oral cavity, and the oral nursing liquid with cleaning tartar effect still belongs in the market Blank.To solve the above problems, the invention provides a kind of oral nursing liquid for clearing up tartar.To solve the above problems, this hair It is bright to provide a kind of oral nursing liquid for clearing up tartar.

The present invention is achieved by the following technical solutions：

A kind of oral nursing liquid for clearing up tartar, it is respectively configured to sub-prime gauge part and is：Gardenia 17-20 parts, orchid 14-18 Part, wintersweet 11-13 parts, Herba Andrographitis 8-12 parts, honeysuckle 7-10 parts, Canton love-pea vine 5-8 parts, folium artemisiae argyi 4-7 parts, Radix Isatidis 4-6 parts, Chang Pu 3-6 parts, trilliaceae extract 6-8 parts, Changnienia amoena extract 5-7 parts, bamboo salt 0.5-1 parts, sodium carbonate 0.4-0.8 parts.

Described trilliaceae extract, its compound method are：

It is 3 to take trilliaceae leaf and flower mass ratio:1, the 50% ethanol stirring of 4-6 times of its quality is milled twice and then added after crushing Mixing, first in -12--9 DEG C of Cord blood 5-7h, 20-30min is vibrated to room temperature ultrasonic after taking-up, then be placed in 60-65 DEG C of temperature Refluxing extraction 1.5-2h is spent, trilliaceae extract is made to extract solution concentration drying.

Described Changnienia amoena extract, its compound method are：

The pure water of slurry 5-7 times of its quality of addition that Changnienia amoena is milled, frequency of use is 11-14kHz and 23-26kHz ultrasounds respectively Ripple alternate oscillation 30-40min, alternately the frequency is 8 times/min, then adds its quality 2%-3% mix bacterium agent fermentation 36-38h, First extract powder processed is dried to obtain in concentration after filtering, then the absolute ethyl alcohol of 4-5 times of its quality is added into just extract powder processed, in 60-64 DEG C refluxing extraction 1-2h, Changnienia amoena extract is made after drying；Described mix bacterium agent, it is hay bacillus, aspergillus oryzae and breast Two or more in sour bacterium.

The oral nursing liquid of described cleaning tartar, comprises the following steps：

（1）Flower liquid extraction：Gardenia, orchid, wintersweet are placed on distillation layer, adding absolute ethyl alcohol in the pot of bottom carries out circulation steaming 20-24min is boiled, drains the water that rear efflorescence adds 4-6 times of its quality, mix bacterium agent fermentation 40-43h, mistake are added after being stirred The 1/5 of original volume is concentrated into after filter, mixing flower extract solution is made, containing fragrance of a flower composition and antipathogenic composition, oral nursing liquid can be made With fresh breath and bacteriostasis；

（2）It is prepared by medicament：Herba Andrographitis, honeysuckle, Canton love-pea vine and folium artemisiae argyi are submerged initially in acetic acid and soak 1-2h, cleaning powder after taking-up Change and add the water and enzyme agent of 3-5 times of its quality, 2-3h is digested after mixing, then in 54-58 DEG C of boiling 50-60min, after filtering Medicament powder A is made in concentration drying, there is anti-inflammation, swelling and pain relieving, stimulate circulation and other effects, can be to periodontals such as gingivitis Disease carries out prophylactic treatment；

（3）Extract powder：It is put into after Radix Isatidis and calamus are crushed and the nothing for slight burnt odor, adding 4-6 times of its quality is fried in frying pan Water-ethanol is in 65-70 DEG C of refluxing extraction 1.5-2h, the obtained medicament powder B of concentration drying after filtering；

（4）Mixing：Remove ionized water 200-240 parts and add bamboo salt and sodium carbonate, be warming up to 46-50 DEG C and add trilliaceae extraction Thing, Changnienia amoena extract, mixing flower extract solution, medicament powder A, medicament powder B, use trilliaceae and only orchid effective for raw material extraction Composition, it has the function that softening, dissolving tartar, 30-40min is incubated after being stirred, and just conditioning liquid processed is made；

（5）It is filling：The use of intensity of illumination is that 310-340lux ultraviolet lights are sterilized to first conditioning liquid processed, it is then bottled rear obtained Oral nursing liquid.

Step（2）Described enzyme agent, wherein pectase：Cellulase quality proportioning is 1:1, its addition be Herba Andrographitis, The 1%-2% of honeysuckle, Canton love-pea vine and folium artemisiae argyi gross mass.

The present invention has advantages below compared with prior art：Composition is prepared, is carried using gardenia, orchid and wintersweet by raw material Take and contain fragrance of a flower composition and antipathogenic composition in composition, can make oral nursing liquid that there is fresh breath and bacteriostasis；Herba Andrographitis, gold The drug ingedients such as honeysuckle flower, Canton love-pea vine, Radix Isatidis, active drug composition can extract by modes such as enzymolysis, boilings, disappear with antibacterial Inflammation, swelling and pain relieving, stimulate circulation and other effects, prophylactic treatment can be carried out to periodontal diseases such as gingivitis, and can be to tartar Emollescence is played, plays cleaning tartar effect；And trilliaceae and only orchid are used as raw material effective component extracting, it has soft Change, the effect of dissolving tartar, play a part of taking care of one's teeth, and also there is the effect of activating blood circulation and reducing swelling.Oral care of the present invention Liquid can play cleaning tartar, fresh breath, improve dental health, can play prevention and treatment to periodontal diseases such as gingivitis again Effect, and it is easy to use, safe.

Embodiment

Embodiment 1：

A kind of oral nursing liquid for clearing up tartar, it is respectively configured to sub-prime gauge part and is：18 parts of gardenia, 15 parts of orchid, wintersweet 11.2 parts, 9 parts of Herba Andrographitis, 8 parts of honeysuckle, 6 parts of Canton love-pea vine, 5 parts of folium artemisiae argyi, 4.3 parts of Radix Isatidis, 4 parts of calamus, trilliaceae extract 6.4 parts, 5.3 parts of Changnienia amoena extract, 0.6 part of bamboo salt, 0.5 part of sodium carbonate.

Described trilliaceae extract, its compound method are：

It is 3 to take trilliaceae leaf and flower mass ratio:1, the 50% ethanol stirring of 4.5 times of its quality is milled twice and then added after crushing Mixing, first in -10 DEG C of Cord blood 5.5h, 23min is vibrated to room temperature ultrasonic after taking-up, then be placed in 62 DEG C of temperature reflux extractions 1.6h, trilliaceae extract is made to extract solution concentration drying.

Described Changnienia amoena extract, its compound method are：

The pure water of slurry 5.5 times of its quality of addition that Changnienia amoena is milled, frequency of use is that 12kHz and 24kHz ultrasonic waves replace respectively 32min is vibrated, alternately the frequency is 8 times/min, then adds the mix bacterium agent fermentation 37h of its quality 2.1%, concentrates and dry after filtering It is dry to obtain just extract powder processed, then add into just extract powder processed the absolute ethyl alcohol of 4.5 times of its quality, in 61 DEG C of refluxing extraction 1.5h, Changnienia amoena extract is made after drying；Described mix bacterium agent, it is two kinds or more in hay bacillus, aspergillus oryzae and lactic acid bacteria Kind.

（1）Flower liquid extraction：Gardenia, orchid, wintersweet are placed on distillation layer, adding absolute ethyl alcohol in the pot of bottom carries out circulation steaming 21min is boiled, drains the water that rear efflorescence adds 4.5 times of its quality, addition mix bacterium agent fermentation 41h, dense after filtering after being stirred The 1/5 of original volume is reduced to, mixing flower extract solution is made, containing fragrance of a flower composition and antipathogenic composition, can have oral nursing liquid clear New implication and bacteriostasis；

（2）It is prepared by medicament：Herba Andrographitis, honeysuckle, Canton love-pea vine and folium artemisiae argyi are submerged initially in acetic acid and soak 1.5h, cleaning powder after taking-up Change water and the enzyme agent for adding 3.5 times of its quality, 2.5h is digested after mixing, then in 55 DEG C of boiling 54min, concentrate and dry after filtering It is drying to obtain medicament powder A, there is anti-inflammation, swelling and pain relieving, stimulate circulation and other effects, the periodontal diseases such as gingivitis can be entered Row prophylactic treatment；

（3）Extract powder：It is put into after Radix Isatidis and calamus are crushed and the nothing for slight burnt odor, adding 4.5 times of its quality is fried in frying pan Water-ethanol is in 66 DEG C of refluxing extraction 1.7h, the obtained medicament powder B of concentration drying after filtering；

（4）Mixing：Remove 210 parts of ionized water and add bamboo salt and sodium carbonate, be warming up to 47 DEG C and add trilliaceae extract, solely flower Blue extract, mixing flower extract solution, medicament powder A, medicament powder B, use trilliaceae and only orchid as raw material effective component extracting, its There is softening, dissolving tartar, 32min is incubated after being stirred, just conditioning liquid processed is made；

（5）It is filling：First conditioning liquid processed is sterilized for 320lux ultraviolet lights using intensity of illumination, then bottled rear obtained oral cavity Conditioning liquid.

Step（2）Described enzyme agent, wherein pectase：Cellulase quality proportioning is 1:1, its addition be Herba Andrographitis, Honeysuckle, the 1.3% of Canton love-pea vine and folium artemisiae argyi gross mass.

Embodiment 2：

A kind of oral nursing liquid for clearing up tartar, it is respectively configured to sub-prime gauge part and is：19 parts of gardenia, 17 parts of orchid, wintersweet 12.5 parts, 11 parts of Herba Andrographitis, 9 parts of honeysuckle, 7 parts of Canton love-pea vine, 6 parts of folium artemisiae argyi, 5.7 parts of Radix Isatidis, 5 parts of calamus, trilliaceae extraction 7.4 parts of thing, 6.5 parts of Changnienia amoena extract, 0.8 part of bamboo salt, 0.7 part of sodium carbonate.

Described trilliaceae extract, its compound method are：

It is 3 to take trilliaceae leaf and flower mass ratio:1, the 50% ethanol stirring of 5.5 times of its quality is milled twice and then added after crushing Mixing, first in -11 DEG C of Cord blood 6.5h, 28min is vibrated to room temperature ultrasonic after taking-up, then be placed in 64 DEG C of temperature reflux extractions 1.8h, trilliaceae extract is made to extract solution concentration drying.

Described Changnienia amoena extract, its compound method are：

The pure water of slurry 6.5 times of its quality of addition that Changnienia amoena is milled, frequency of use is that 13kHz and 25kHz ultrasonic waves replace respectively 37min is vibrated, alternately the frequency is 8 times/min, then adds the mix bacterium agent fermentation 38h of its quality 2.8%, concentrates and dry after filtering First extract powder processed is done to obtain, then the absolute ethyl alcohol of 5 times of its quality is added into just extract powder processed, in 63 DEG C of refluxing extraction 2h, drying Changnienia amoena extract is made afterwards；Described mix bacterium agent, it is two or more in hay bacillus, aspergillus oryzae and lactic acid bacteria.

（1）Flower liquid extraction：Gardenia, orchid, wintersweet are placed on distillation layer, adding absolute ethyl alcohol in the pot of bottom carries out circulation steaming 23min is boiled, drains the water that rear efflorescence adds 5.5 times of its quality, addition mix bacterium agent fermentation 42h, dense after filtering after being stirred The 1/5 of original volume is reduced to, mixing flower extract solution is made, containing fragrance of a flower composition and antipathogenic composition, can have oral nursing liquid clear New implication and bacteriostasis；

（2）It is prepared by medicament：Herba Andrographitis, honeysuckle, Canton love-pea vine and folium artemisiae argyi are submerged initially in acetic acid and soak 2h, efflorescence is cleaned after taking-up The water and enzyme agent of 4.5 times of its quality are added, 3h is digested after mixing, then in 57 DEG C of boiling 58min, concentration drying system after filtering Medicament powder A being obtained, there is anti-inflammation, swelling and pain relieving, stimulate circulation and other effects, the periodontal diseases such as gingivitis can be carried out pre- Anti- treatment；

（3）Extract powder：It is put into after Radix Isatidis and calamus are crushed and the nothing for slight burnt odor, adding 5.5 times of its quality is fried in frying pan Water-ethanol is in 69 DEG C of refluxing extraction 1.8h, the obtained medicament powder B of concentration drying after filtering；

（4）Mixing：Remove 230 parts of ionized water and add bamboo salt and sodium carbonate, be warming up to 49 DEG C and add trilliaceae extract, solely flower Blue extract, mixing flower extract solution, medicament powder A, medicament powder B, use trilliaceae and only orchid as raw material effective component extracting, its There is softening, dissolving tartar, 38min is incubated after being stirred, just conditioning liquid processed is made；

（5）It is filling：First conditioning liquid processed is sterilized for 330lux ultraviolet lights using intensity of illumination, then bottled rear obtained oral cavity Conditioning liquid.

Step（2）Described enzyme agent, wherein pectase：Cellulase quality proportioning is 1:1, its addition be Herba Andrographitis, Honeysuckle, the 1.8% of Canton love-pea vine and folium artemisiae argyi gross mass.

Contrast 1：

Trilliaceae extract, other steps and the phase of embodiment 1 is not used compared with embodiment 1 in this contrast 1 in oral nursing liquid Together.

Contrast 2：

Only orchid extract, other steps and the phase of embodiment 1 is not used compared with embodiment 1 in this contrast 2 in oral nursing liquid Together.

Contrast 3：

Mixing flower extract solution, other steps and the phase of embodiment 1 is not used in this contrast 3 compared with embodiment 1, in oral nursing liquid Together.

Contrast 4：

Medicament powder A is not used compared with embodiment 2 in this contrast 4 in oral nursing liquid, other steps are same as Example 2.

Contrast 5：

Medicament powder B is not used compared with embodiment 2 in this contrast 5 in oral nursing liquid, other steps are same as Example 2.

Control group：

Control group is cleared up tartar using teeth brushing way, and trilliaceae extract, Changnienia amoena extract, mixing flower is not used and carries Take liquid, medicament powder A, medicament powder B.

To oral care obtained by embodiment 1, embodiment 2, contrast 1, contrast 2, contrast 3, contrast 4, contrast 5 and control group Liquid, tartar crowd, gingivitis patients and tooth jaundice person are used in an identical manner, statistics tartar cleaning rate, gingivitis are controlled More rate, tooth whitening rate.

Experimental data：

Project	Tartar cleaning rate %	Gingivitis cure rate %	Tooth whitening rate %
				Embodiment 1	92.6	86.10	71.2
Embodiment 2	91.3	85.40	70.6
				Contrast 1	82.9	86.70	65.6
Contrast 2	81.5	85.80	64.9
				Contrast 3	92.1	81.62	71.8
Contrast 4	87.4	76.44	68.5
				Contrast 5	88.1	77.23	68.8
Control group	64.7	64.5	55.4

Synthesis result：The made oral nursing liquid of the present invention, compared with control group, tartar cleaning rate improves 27.9%, and gingivitis is cured Rate improves 21.6%, and tooth whitening rate improves 15.8%.Using trilliaceae extract and Changnienia amoena extract, tartar cleaning can be improved Rate is 9.7%, 11.1%, and tooth whitening rate improves 5.6%, 6.3%；Using mixing flower extract solution, can improve gum cure rate is 4.5%, and medicament powder A and medicament powder B is used, it is 9.0%, 8.2% that can improve gum cure rate, tartar cleaning rate raising 3.9%, 3.2%。

Claims

1. a kind of oral nursing liquid for clearing up tartar, it is characterised in that it is respectively configured to sub-prime gauge part and is：Gardenia 17-20 Part, orchid 14-18 parts, wintersweet 11-13 parts, Herba Andrographitis 8-12 parts, honeysuckle 7-10 parts, Canton love-pea vine 5-8 parts, folium artemisiae argyi 4-7 parts, plate Blue root 4-6 parts, calamus 3-6 parts, trilliaceae extract 6-8 parts, Changnienia amoena extract 5-7 parts, bamboo salt 0.5-1 parts, sodium carbonate 0.4-0.8 parts.

2. the oral nursing liquid of cleaning tartar as claimed in claim 1, it is characterised in that described trilliaceae extract, its Compound method is：

3. the oral nursing liquid of cleaning tartar as claimed in claim 1, it is characterised in that described Changnienia amoena extract, its Compound method is：

4. the oral nursing liquid of cleaning tartar as claimed in claim 1, it is characterised in that comprise the following steps：

（1）Flower liquid extraction：Gardenia, orchid, wintersweet are placed on distillation layer, adding absolute ethyl alcohol in the pot of bottom carries out circulation steaming 20-24min is boiled, drains the water that rear efflorescence adds 4-6 times of its quality, mix bacterium agent fermentation 40-43h, mistake are added after being stirred The 1/5 of original volume is concentrated into after filter, mixing flower extract solution is made；

（2）It is prepared by medicament：Herba Andrographitis, honeysuckle, Canton love-pea vine and folium artemisiae argyi are submerged initially in acetic acid and soak 1-2h, cleaning powder after taking-up Change and add the water and enzyme agent of 3-5 times of its quality, 2-3h is digested after mixing, then in 54-58 DEG C of boiling 50-60min, after filtering Medicament powder A is made in concentration drying；

（4）Mixing：Remove ionized water 200-240 parts and add bamboo salt and sodium carbonate, be warming up to 46-50 DEG C and add trilliaceae extraction Thing, Changnienia amoena extract, mixing flower extract solution, medicament powder A, medicament powder B, are incubated 30-40min after being stirred, are made and just make Conditioning liquid；

5. the oral nursing liquid of cleaning tartar as claimed in claim 4, it is characterised in that step（2）Described enzyme agent, wherein Pectase：Cellulase quality proportioning is 1:1, its addition is the 1%- of Herba Andrographitis, honeysuckle, Canton love-pea vine and folium artemisiae argyi gross mass 2%。