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CN107736956A - Artificial intelligence cervical intervertebral disc capable of recording pressure and movement - Google Patents

Artificial intelligence cervical intervertebral disc capable of recording pressure and movement Download PDF

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Publication number
CN107736956A
CN107736956A CN201710993408.7A CN201710993408A CN107736956A CN 107736956 A CN107736956 A CN 107736956A CN 201710993408 A CN201710993408 A CN 201710993408A CN 107736956 A CN107736956 A CN 107736956A
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support body
pressure
intervertebral disc
lower plate
artificial intelligence
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CN107736956B (en
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王贝宇
吴廷奎
刘浩
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West China Hospital of Sichuan University
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West China Hospital of Sichuan University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools for implanting artificial joints
    • A61F2/4657Measuring instruments used for implanting artificial joints
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools for implanting artificial joints
    • A61F2/4657Measuring instruments used for implanting artificial joints
    • A61F2002/4666Measuring instruments used for implanting artificial joints for measuring force, pressure or mechanical tension
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools for implanting artificial joints
    • A61F2/4657Measuring instruments used for implanting artificial joints
    • A61F2002/4668Measuring instruments used for implanting artificial joints for measuring angles

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

本发明涉及一种可记录压力和运动的人工智能颈椎间盘,包括上板、支撑体、下板、至少一个压力传感器、角度位移感受器、无线通讯模块以及微型电池,支撑体与上板可相对活动,支撑体为高分子材料,支撑体内设有压力传感器、无线通讯模块和微型电池,上板和下板内均设有角度位移感受器、无线通讯模块和微型电池。本发明中支撑体可单独更换,可通过微创手术进行更换,避免板骨愈合界面的再次破坏;支撑体通过压力感受器可实时感应压力变化以及压力位置分布,角度位移感受器可独立实时记录三维空间的角度变化参数,可无创、不间断的实时监测假体的功能和状态,从而详细评估患者在颈椎人工椎间盘置换术后近期及中远期风险、指导康训练。

The invention relates to an artificial intelligence cervical intervertebral disc capable of recording pressure and motion, comprising an upper plate, a support body, a lower plate, at least one pressure sensor, an angle displacement sensor, a wireless communication module and a micro battery, and the support body and the upper plate can move relatively , the supporting body is a polymer material, a pressure sensor, a wireless communication module and a micro battery are arranged in the supporting body, and an angle displacement sensor, a wireless communication module and a micro battery are arranged in the upper plate and the lower plate. In the present invention, the support body can be replaced separately, and can be replaced by minimally invasive surgery to avoid further destruction of the plate-bone healing interface; the support body can sense pressure changes and pressure position distribution in real time through the pressure sensor, and the angular displacement sensor can independently record the three-dimensional space in real time It can monitor the function and state of the prosthesis non-invasively and continuously in real time, so as to evaluate the short-term, mid- and long-term risks of patients after cervical artificial disc replacement in detail, and guide health training.

Description

一种可记录压力和运动的人工智能颈椎间盘An AI-powered cervical disc that records pressure and motion

技术领域technical field

本发明涉及医疗器械技术领域,尤其涉及一种可记录压力和运动的人工智能颈椎间盘The invention relates to the technical field of medical devices, in particular to an artificial intelligence cervical intervertebral disc that can record pressure and motion

背景技术Background technique

颈椎为了适应视觉,听觉和嗅觉的刺激反应,需要有较大而敏锐的可动性。因此,颈椎的活动范围要比胸椎和腰椎大得多,如前屈后伸、左右侧屈、左右旋转以及上述运动综合形成的环转运动。In order to adapt to visual, auditory and olfactory stimuli, the cervical spine needs greater and sharper mobility. Therefore, the range of motion of the cervical spine is much larger than that of the thoracic and lumbar spine, such as forward flexion and rear extension, left and right lateral flexion, left and right rotation, and the circular movement formed by the above-mentioned movements.

颈椎间盘是位于颈椎两椎体之间,由软骨板、纤维环、髓核组成的一个密封体。上下有软骨板,是透明软骨覆盖于椎体上,下面骺环中间的骨面。上下的软骨板与纤维环一起将髓核密封起来。纤维环由胶原纤维束的纤维软骨构成,位于髓核的四周。纤维环的纤维束相互斜行交叉重叠,使纤维环成为坚实的组织,能承受较大的弯曲和扭转负荷。对于颈椎间盘切除后的患者需要用到人工颈椎间盘。The cervical intervertebral disc is located between the two vertebral bodies of the cervical spine and is composed of a cartilage plate, annulus fibrosus, and nucleus pulposus. There are cartilage plates on the upper and lower sides, which are hyaline cartilage covering the vertebral body and the bony surface in the middle of the lower epiphyseal ring. The upper and lower cartilage plates seal the nucleus pulposus together with the annulus fibrosus. The annulus fibrosus is composed of fibrocartilage of collagen fiber bundles and is located around the nucleus pulposus. The fiber bundles of the annulus fibrosus intersect obliquely and overlap each other, making the annulus fibrosus a solid tissue that can withstand large bending and torsional loads. For patients after cervical discectomy, artificial cervical discs are needed.

但是通过手术植入人工颈椎间盘后,医生只能定期(例如术后1周、3个月、6个月、1年、2年等)通过多次复查颈椎X线、CT等办法对病人进行人工椎间盘在体内的功能评估,这种状态评估实际是对某时间点状态的评估,不能反应人工椎间盘在各种姿势、动作、状态下的全面动态的状态。且目前复查的X、CT等检查手段所产生的辐射,是患者复查时难以避免的。However, after the artificial cervical intervertebral disc is surgically implanted, the doctor can only periodically (for example, 1 week, 3 months, 6 months, 1 year, 2 years, etc.) review the cervical spine X-ray, CT, etc. The function evaluation of the artificial intervertebral disc in the body, this state evaluation is actually the evaluation of the state at a certain point in time, and cannot reflect the overall dynamic state of the artificial intervertebral disc in various postures, actions, and states. Moreover, the radiation produced by the current review methods such as X and CT is unavoidable when patients are reviewed.

发明内容Contents of the invention

本发明旨在提供一种可记录压力和运动的人工智能颈椎间盘,以代替原来的颈椎间盘并行使其功能,实现保留运动节段、避免相邻节段出现继发性退变,并通过其内的感应器实时反应人工颈椎间盘的功能状态。The present invention aims to provide an artificial intelligence cervical intervertebral disc that can record pressure and motion, to replace the original cervical intervertebral disc and perform its function, realize the preservation of motion segments, avoid secondary degeneration of adjacent segments, and through its The internal sensor reflects the functional status of the artificial cervical intervertebral disc in real time.

为达到上述目的,本发明采用的技术方案如下:In order to achieve the above object, the technical scheme adopted in the present invention is as follows:

一种可记录压力和运动的人工智能颈椎间盘,包括上板、支撑体、下板、至少一个压力传感器、角度位移感受器、无线通讯模块以及用于供电的微型电池,支撑体顶部与上板连接,支撑体底部与下板连接,支撑体与下板静联接,所述支撑体与上板可相对活动,所述支撑体为高分子材料,所述支撑体内设有压力传感器、无线通讯模块和微型电池,上板和下板内均设有角度位移感受器、无线通讯模块和微型电池,所述压力传感器和角度位移感受器均与无线通讯模块电联接。An artificial intelligence cervical intervertebral disc capable of recording pressure and motion, including an upper plate, a support body, a lower plate, at least one pressure sensor, an angle displacement sensor, a wireless communication module and a micro battery for power supply, the top of the support body is connected to the upper plate , the bottom of the support body is connected to the lower plate, the support body is statically connected to the lower plate, the support body and the upper plate can move relatively, the support body is made of a polymer material, and a pressure sensor, a wireless communication module and a pressure sensor are arranged in the support body. A micro battery, an angle displacement sensor, a wireless communication module and a micro battery are arranged in the upper plate and the lower plate, and the pressure sensor and the angle displacement sensor are electrically connected with the wireless communication module.

进一步的,支撑体的上表面为外凸的弧面,上板的下表面有与支撑体上表面适配的圆形凹槽,支撑体与圆形凹槽间隙配合,所述支撑体的下表面设有至少两个卡槽,所述卡槽围绕支撑体的轴线等间隔设置,下板的顶面有与卡槽适配的卡块。Further, the upper surface of the support body is a convex arc surface, the lower surface of the upper plate has a circular groove adapted to the upper surface of the support body, the support body and the circular groove fit in a gap, and the lower surface of the support body The surface is provided with at least two draw-in slots, and the draw-in slots are arranged at equal intervals around the axis of the support body, and the top surface of the lower plate has a block adapted to the draw-in slots.

进一步的,所述支撑体的上表面为外凸的弧面,所述支撑体的下表面为平面。Further, the upper surface of the support body is a convex arc surface, and the lower surface of the support body is a plane.

进一步的,所述上板和下板内各设有一个陀螺仪,所述陀螺仪与无线通讯模块电联接。Further, each of the upper board and the lower board is provided with a gyroscope, and the gyroscope is electrically connected to the wireless communication module.

其中,所述上板的上表面的中央设有一排齿棘A,下板的下表面设有两排齿棘B,两排齿棘B分别位于下板的左右两侧,齿棘A的排列方向与齿棘B的排列方向平行。Wherein, the center of the upper surface of the upper plate is provided with a row of ratchets A, and the lower surface of the lower plate is provided with two rows of ratchets B, and the two rows of ratchets B are respectively located on the left and right sides of the lower plate. The direction is parallel to the arrangement direction of the toothed ratchet B.

进一步的,所述下板左右两侧上翘。Further, the left and right sides of the lower plate are upturned.

其中,所述上板和下板的左右两侧均有便于夹持的缺口,上板上的缺口贯通上板的上表面和下表面,下板上的缺口贯通下板的上表面和下表面。Wherein, the left and right sides of the upper plate and the lower plate have gaps for easy clamping, the gaps on the upper plate penetrate the upper surface and the lower surface of the upper plate, and the gaps on the lower plate penetrate the upper surface and the lower surface of the lower plate .

进一步的,上板和下板的外表面有钽金属涂层。Further, the outer surfaces of the upper plate and the lower plate are coated with tantalum metal.

其中,支撑体的材质为聚醚醚酮。进一步的,卡槽贯穿支撑体的上表面、下表面和侧面。Wherein, the material of the support body is polyether ether ketone. Further, the card slot runs through the upper surface, the lower surface and the side surface of the support body.

与现有技术相比,本发明具有以下有益效果:Compared with the prior art, the present invention has the following beneficial effects:

1.支撑体通过压力感受器可实时感应压力变化以及压力位置分布,上下板内的角度位移感受器可独立实时记录三维空间X、Y、Z轴空间的角度变化参数。以上压力和角度记录参数均可通过无线通讯模块汇总并与外界匹配的通讯模块进行数据传输。该装置能实现无创、持续不间断的实时监测假体的功能和状态,从而详细评估患者在颈椎人工椎间盘置换术后近期及中远期风险、指导康训练;1. The support body can sense the pressure change and pressure position distribution in real time through the pressure sensor, and the angle displacement sensor in the upper and lower plates can independently record the angle change parameters of the X, Y, and Z axes in the three-dimensional space in real time. The above pressure and angle recording parameters can be summarized through the wireless communication module and communicated with the external matching communication module for data transmission. The device can realize non-invasive, continuous and uninterrupted real-time monitoring of the function and status of the prosthesis, so as to assess the short-term, mid- and long-term risks of patients after cervical artificial disc replacement in detail, and guide health training;

2.本发明中支撑体可单独更换,当支撑体磨损后或体内工作不理想时,可通过微创手术进行更换,避免板骨愈合界面的再次破坏。2. In the present invention, the supporting body can be replaced separately. When the supporting body is worn out or the internal work is not ideal, it can be replaced by minimally invasive surgery to avoid further destruction of the plate-bone healing interface.

附图说明Description of drawings

图1是实施例1的分解图;Fig. 1 is the exploded view of embodiment 1;

图2是实施例1中支撑体安装在下板上时的示意图;Fig. 2 is the schematic diagram when support body is installed on lower plate in embodiment 1;

图3是本发明的三维图;Fig. 3 is a three-dimensional diagram of the present invention;

图4是上板的结构示意图;Fig. 4 is the structural representation of upper plate;

图5是实施例1中下板的立体图;Fig. 5 is the perspective view of lower plate in embodiment 1;

图6是实施例1中下板的主视图;Fig. 6 is the front view of lower plate in embodiment 1;

图7是支撑体的结构示意图;Fig. 7 is the structural representation of support body;

图中:1-上板、2-支撑体、3-下板、4-卡槽、5-卡块、6-齿棘A、7-齿棘B、8-弯曲部、9-缺口、10-圆形凹槽。In the figure: 1-upper plate, 2-support body, 3-lower plate, 4-card slot, 5-block, 6-toothed ratchet A, 7-toothed ratchet B, 8-curved portion, 9-notch, 10 - Round grooves.

具体实施方式detailed description

为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图,对本发明进行进一步详细说明。In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings.

实施例1Example 1

如图1、2、3所示,本实施例公开的可记录压力和运动的人工智能颈椎间盘,包括上板1、支撑体2、下板3、至少一个压力传感器、角度位移感受器、无线通讯模块以及用于供电的微型电池,支撑体2顶部与上板1连接,支撑体2底部与下板3连接,支撑体2与下板3静联接,支撑体2与上板1可相对活动,支撑体2为高分子材料,支撑体2内设有压力传感器、无线通讯模块和微型电池,上板1和下板3内均设有角度位移感受器、无线通讯模块和微型电池,压力传感器和角度位移感受器均与无线通讯模块电联接。压力传感器可准确测量压力的变化,,通过实时监测,方便指导术后康复及训练跟进,压力过大或分布不均可导致假体功能损失和磨损。无线通讯模块将压力传感器、角度位移感受器的测量信号传输至体外终端以及接收处理执行指令。上板1和下板3的外表面有钽金属涂层,支撑体2的材质为聚醚醚酮,polyetheretherketone(简称PEEK)。As shown in Figures 1, 2, and 3, the artificial intelligence cervical intervertebral disc disclosed in this embodiment that can record pressure and motion includes an upper plate 1, a support body 2, a lower plate 3, at least one pressure sensor, an angular displacement sensor, a wireless communication The module and the micro battery used for power supply, the top of the support body 2 is connected with the upper board 1, the bottom of the support body 2 is connected with the lower board 3, the support body 2 and the lower board 3 are statically connected, and the support body 2 and the upper board 1 can move relatively. The support body 2 is a polymer material, and the support body 2 is equipped with a pressure sensor, a wireless communication module and a micro battery, and the upper plate 1 and the lower plate 3 are equipped with an angle displacement sensor, a wireless communication module and a micro battery, the pressure sensor and the angle The displacement sensors are all electrically connected with the wireless communication module. The pressure sensor can accurately measure the change of pressure. Through real-time monitoring, it is convenient to guide postoperative rehabilitation and training follow-up. Excessive pressure or uneven distribution can lead to functional loss and wear of the prosthesis. The wireless communication module transmits the measurement signals of the pressure sensor and the angle displacement sensor to the external terminal and receives processing execution instructions. The outer surfaces of the upper plate 1 and the lower plate 3 are coated with tantalum metal, and the material of the support body 2 is polyetheretherketone (PEEK for short).

支撑体2内可设置等横截面积的压力传感器也可以设置多个压力感受器。使用时,每一个支撑体2具有唯一数码识别标志,可通过软件或者APP读取其在体内的压力变化。Pressure sensors with equal cross-sectional areas can be arranged in the support body 2, and a plurality of pressure receptors can also be arranged. When in use, each support body 2 has a unique digital identification mark, and its pressure change in the body can be read through software or APP.

如图7所示,支撑体2的上表面为外凸的弧面,上板1的下表面有与支撑体4上表面适配的圆形凹槽10,支撑体2与圆形凹槽10间隙配合,使支撑体2可相对于上板1转动。支撑体2的下表面设有至少两个卡槽4,卡槽4围绕支撑体2的轴线等间隔设置,下板3的顶面有与卡槽4适配的卡块5。支撑体2的下表面为平面,下板3与支撑体2的接触面为平面。卡槽4贯穿支撑体2的上表面、下表面和侧面。As shown in Figure 7, the upper surface of the support body 2 is a convex arc surface, the lower surface of the upper plate 1 has a circular groove 10 adapted to the upper surface of the support body 4, the support body 2 and the circular groove 10 The clearance fit enables the supporting body 2 to rotate relative to the upper plate 1 . The lower surface of the supporting body 2 is provided with at least two locking grooves 4 , and the locking grooves 4 are arranged at equal intervals around the axis of the supporting body 2 . The lower surface of the support body 2 is a plane, and the contact surface between the lower plate 3 and the support body 2 is a plane. The slot 4 runs through the upper surface, the lower surface and the side surface of the support body 2 .

其中,如图4所示,上板1的上表面的中央设有一排齿棘A6,齿棘A6有3个。如图5所示,下板3的下表面设有两排齿棘B7,两排齿棘B7分别位于下板3的左右两侧,齿棘A6的排列方向与齿棘B7的排列方向平行,每排有两个齿棘B7。Wherein, as shown in FIG. 4 , a row of ratchets A6 is arranged in the center of the upper surface of the upper plate 1 , and there are three ratchets A6 . As shown in Figure 5, two rows of ratchets B7 are provided on the lower surface of the lower plate 3, and the two rows of ratchets B7 are respectively located on the left and right sides of the lower plate 3, and the arrangement direction of the ratchets A6 is parallel to the arrangement direction of the ratchets B7. Each row has two toothed ratchets B7.

如图5、6所示,下板3左右两侧上翘,形成顺应钩椎关节形态的弯曲部8,当支撑体2安装在下板3上时,弯曲部8的高度不高于支撑体2。其中,上板1和下板3的左右两侧均有便于夹持的缺口9,上板1上的缺口9贯通上板1的上表面和下表面,下板3上的缺口9贯通下板3的上表面和下表面。As shown in Figures 5 and 6, the left and right sides of the lower plate 3 are upturned to form a curved part 8 conforming to the shape of the hook-vertebral joint. When the support body 2 is installed on the lower plate 3, the height of the curved part 8 is not higher than that of the support body 2. . Wherein, the left and right sides of the upper plate 1 and the lower plate 3 have notches 9 for easy clamping, the notches 9 on the upper plate 1 penetrate the upper surface and the lower surface of the upper plate 1, and the notches 9 on the lower plate 3 penetrate the lower plate 3 on the upper and lower surfaces.

本发明中支撑体2与上板1间隙配合,与下板3卡接,可单独取下支撑体2,当支撑体2磨损后或体内工作不理想时,可进行微创手术单独更换,避免板骨界面的损害。In the present invention, the supporting body 2 is matched with the upper plate 1 in a gap, and is clamped with the lower plate 3. The supporting body 2 can be removed separately. Damage to the plate-bone interface.

通过压力,指导术中人工颈椎间盘的高度及置入位置的判断,操作简单安全。实时记录术后假体在体内真实的压力变化,无损无害实时监测假体的功能和状态,从而评估患者在置换术后近期及中远期风险、指导康复训练。Through the pressure, it guides the judgment of the height of the artificial cervical intervertebral disc and the placement position during the operation, and the operation is simple and safe. Real-time recording of the real pressure changes of the postoperative prosthesis in the body, non-destructive and harmless real-time monitoring of the function and status of the prosthesis, so as to assess the short-term, mid- and long-term risks of patients after replacement, and guide rehabilitation training.

实施例2Example 2

本实施例与实施例1的区别在于:上板1和下板3内各设有一个陀螺仪,陀螺仪与无线通讯模块电联接。陀螺仪也由微型电池供电。上板1和下板3内的角度位移感受器可独立实时记录三维空间X、Y、Z轴空间的角度变化参数。无线通讯模块将陀螺仪的信号传输至体外终端以及接收处理执行指令。The difference between this embodiment and Embodiment 1 is that: each of the upper board 1 and the lower board 3 is provided with a gyroscope, and the gyroscope is electrically connected with the wireless communication module. The gyroscope is also powered by tiny batteries. The angular displacement sensors in the upper plate 1 and the lower plate 3 can independently and real-time record the angular change parameters of the X, Y, and Z axes in the three-dimensional space. The wireless communication module transmits the signal of the gyroscope to the external terminal and receives, processes and executes instructions.

本发明中支撑体可单独更换,当支撑体磨损后或体内工作不理想时,可通过微创手术进行更换,避免板骨愈合界面的再次破坏;支撑体通过压力感受器可实时感应压力变化以及压力位置分布,上下板内的角度位移感受器可独立实时记录三维空间X、Y、Z轴空间的角度变化参数。以上压力和角度记录参数均可通过无线通讯模块汇总并与外界匹配的通讯模块进行数据传输。该装置能实现无创、持续不间断的实时监测假体的功能和状态,从而详细评估患者在颈椎人工椎间盘置换术后近期及中远期风险、指导康训练。In the present invention, the support body can be replaced separately. When the support body is worn out or the internal work is not ideal, it can be replaced through minimally invasive surgery to avoid further damage to the plate-bone healing interface; the support body can sense pressure changes and pressure in real time through the pressure receptor Position distribution, the angular displacement sensors in the upper and lower plates can independently record the angular change parameters of the three-dimensional space X, Y, and Z axes in real time. The above pressure and angle recording parameters can be summarized through the wireless communication module and communicated with the external matching communication module for data transmission. The device can realize non-invasive, continuous and uninterrupted real-time monitoring of the function and status of the prosthesis, so as to assess the short-term, mid- and long-term risks of patients after cervical artificial disc replacement in detail, and guide health training.

当然,本发明还可有其它多种实施方式,在不背离本发明精神及其实质的情况下,熟悉本领域的技术人员可根据本发明作出各种相应的改变和变形,但这些相应的改变和变形都应属于本发明所附的权利要求的保护范围。Certainly, the present invention also can have other multiple implementation modes, without departing from the spirit and essence of the present invention, those skilled in the art can make various corresponding changes and deformations according to the present invention, but these corresponding changes All changes and modifications should belong to the scope of protection of the appended claims of the present invention.

Claims (10)

1.一种可记录压力和运动的人工智能颈椎间盘,其特征在于:包括上板(1)、支撑体(2)、下板(3)、至少一个压力传感器、角度位移感受器、无线通讯模块以及用于供电的微型电池,支撑体(2)顶部与上板(1)连接,支撑体(2)底部与下板(3)连接,支撑体(2)与下板(3)静联接,所述支撑体(2)与上板(1)可相对活动,所述支撑体(2)为高分子材料,所述支撑体(2)内设有压力传感器、无线通讯模块和微型电池,上板(1)和下板(3)内均设有角度位移感受器、无线通讯模块和微型电池,所述压力传感器和角度位移感受器均与无线通讯模块电联接。1. A kind of artificial intelligence cervical intervertebral disc that can record pressure and motion is characterized in that: comprise upper plate (1), support body (2), lower plate (3), at least one pressure sensor, angular displacement receptor, wireless communication module and a micro battery for power supply, the top of the support (2) is connected to the upper plate (1), the bottom of the support (2) is connected to the lower plate (3), and the support (2) is statically connected to the lower plate (3), The support body (2) and the upper plate (1) can move relatively, the support body (2) is a polymer material, and a pressure sensor, a wireless communication module and a micro battery are arranged in the support body (2). The board (1) and the lower board (3) are equipped with an angle displacement sensor, a wireless communication module and a micro battery, and the pressure sensor and the angle displacement sensor are electrically connected with the wireless communication module. 2.根据权利要求1所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:所述支撑体(2)的上表面为外凸的弧面,上板(1)的下表面有与支撑体(4)上表面适配的圆形凹槽(10),支撑体(2)与圆形凹槽(10)间隙配合,所述支撑体(2)的下表面设有至少两个卡槽(4),所述卡槽(4)围绕支撑体(2)的轴线等间隔设置,下板(3)的顶面有与卡槽(4)适配的卡块(5)。2. The artificial intelligence cervical intervertebral disc that can record pressure and motion according to claim 1 is characterized in that: the upper surface of the support body (2) is a convex arc surface, and the lower surface of the upper plate (1) has A circular groove (10) adapted to the upper surface of the support body (4), the support body (2) is in clearance fit with the circular groove (10), and the lower surface of the support body (2) is provided with at least two The clamping slots (4), the clamping slots (4) are arranged at equal intervals around the axis of the support body (2), and the top surface of the lower plate (3) has a clamping block (5) adapted to the clamping slots (4). 3.根据权利要求2所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:所述支撑体(2)的下表面为平面。3. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 2, characterized in that: the lower surface of the support body (2) is a plane. 4.根据权利要求1所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:所述上板(1)和下板(3)内各设有一个陀螺仪,所述陀螺仪与无线通讯模块电联接。4. The artificial intelligence cervical intervertebral disc that can record pressure and motion according to claim 1, is characterized in that: each is provided with a gyroscope in the described upper plate (1) and lower plate (3), and described gyroscope and The wireless communication module is electrically connected. 5.根据权利要求1所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:所述上板(1)的上表面的中央设有一排齿棘A(6),下板(3)的下表面设有两排齿棘B(7),两排齿棘B(7)分别位于下板(3)的左右两侧,齿棘A(6)的排列方向与齿棘B(7)的排列方向平行。5. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 1 is characterized in that: the center of the upper surface of the upper plate (1) is provided with a row of ratchets A (6), and the lower plate (3 ) is provided with two rows of ratchets B (7) on the lower surface, and the two rows of ratchets B (7) are respectively located on the left and right sides of the lower plate (3). ) are arranged parallel to each other. 6.根据权利要求1或5所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:所述下板(3)左右两侧上翘。6. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 1 or 5, characterized in that: the left and right sides of the lower plate (3) are upturned. 7.根据权利要求1所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:所述上板(1)和下板(3)的左右两侧均有便于夹持的缺口(9),上板(1)上的缺口(9)贯通上板(1)的上表面和下表面,下板(3)上的缺口(9)贯通下板(3)的上表面和下表面。7. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 1, characterized in that: the left and right sides of the upper plate (1) and the lower plate (3) have gaps (9) for easy clamping ), the notch (9) on the upper plate (1) runs through the upper surface and the lower surface of the upper plate (1), and the notch (9) on the lower plate (3) runs through the upper surface and the lower surface of the lower plate (3). 8.根据权利要求1所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:上板(1)和下板(3)的外表面有钽金属涂层。8. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 1, characterized in that: the outer surfaces of the upper plate (1) and the lower plate (3) are coated with tantalum metal. 9.根据权利要求1所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:支撑体(2)的材质为聚醚醚酮。9. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 1, characterized in that: the support body (2) is made of polyether ether ketone. 10.根据权利要求2所述的可记录压力和运动的人工智能颈椎间盘,其特征在于:卡槽(4)贯穿支撑体(2)的上表面、下表面和侧面。10. The artificial intelligence cervical intervertebral disc capable of recording pressure and motion according to claim 2, characterized in that: the card slot (4) runs through the upper surface, lower surface and side surfaces of the support body (2).
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108969162A (en) * 2018-07-27 2018-12-11 深圳清华大学研究院 A kind of intervertebral motion retaining device
CN111821073A (en) * 2020-08-20 2020-10-27 四川大学华西医院 Orthopedic implant system and monitoring method for monitoring activity posture and stress changes
CN111839834A (en) * 2020-08-20 2020-10-30 四川大学华西医院 Intelligent uncinate vertebra joint stress monitoring system and method
CN111938881A (en) * 2020-08-20 2020-11-17 四川大学华西医院 Intelligent intervertebral disc system and monitoring method capable of monitoring active posture and stress
CN111973324A (en) * 2020-08-20 2020-11-24 四川大学华西医院 Orthopedic implant system based on stress self-adaption controllable adjustment and control method thereof
CN112294502A (en) * 2020-10-30 2021-02-02 四川大学华西医院 Assembly type total intervertebral disc prosthesis based on 3D printing technology and manufacturing method thereof
CN113124744A (en) * 2021-04-20 2021-07-16 电子科技大学 Intelligent intervertebral trial mold, implant and control method
CN115281900A (en) * 2022-08-17 2022-11-04 四川大学华西医院 Automatic adjusting system for rotation center of intervertebral disc prosthesis

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN208573862U (en) * 2017-09-30 2019-03-05 四川大学华西医院 Artificial intelligence cervical intervertebral disc capable of recording pressure and movement

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050070913A1 (en) * 2003-09-29 2005-03-31 Milbocker Michael T. Devices and methods for spine repair
US20080019970A1 (en) * 2006-07-07 2008-01-24 Gorman James R Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures
CN101114531A (en) * 2007-07-23 2008-01-30 金连河 Automatic centering level system of tripod
US20090043391A1 (en) * 2007-08-09 2009-02-12 Spinalmotion, Inc. Customized Intervertebral Prosthetic Disc with Shock Absorption
CN101534751A (en) * 2006-09-15 2009-09-16 先锋外科技术公司 Joint arthroplasty devices having articulating members
US20100016972A1 (en) * 2008-07-17 2010-01-21 Spinalmotion, Inc. Artificial Intervertebral Disc Placement System
CN201757949U (en) * 2010-05-25 2011-03-09 上海中医药大学附属岳阳中西医结合医院 Semi-on-body biomechanical model of cervical structure simulating extensor muscles of posterior neck
CN103006356A (en) * 2013-01-07 2013-04-03 刘小勇 Bionic type hydraulic movable artificial vertebral body
US20130261503A1 (en) * 2012-03-31 2013-10-03 Jason T. Sherman System and method for validating an orthopaedic surgical plan
US20150039089A1 (en) * 2013-07-31 2015-02-05 Globus Medical, Inc. Artificial Disc Devices and Related Methods of Use
CN104546229A (en) * 2015-01-19 2015-04-29 南京航空航天大学 Artificial cervical intervertebral disc with ultrahigh activity type chamfering U-shaped structure
CN204839838U (en) * 2015-06-23 2015-12-09 深圳兰度生物材料有限公司 Artifical neck intervertebral disc false body
CN105534623A (en) * 2016-01-12 2016-05-04 四川大学华西医院 Bionic artificial intervertebral disc
CN105708584A (en) * 2016-01-18 2016-06-29 无锡宝通医疗投资有限公司 Integral bionic cervical disc prosthesis
CN105726278A (en) * 2016-04-25 2016-07-06 四川乐彤科技有限公司 Intelligent cervical vertebra massage robot with multiple degrees of freedom
US20170173326A1 (en) * 2015-12-22 2017-06-22 Ecole Polytechnique Federale De Lausanne (Epfl) System for selective spatiotemporal stimulation of the spinal cord
US20170196508A1 (en) * 2014-06-25 2017-07-13 Canary Medical Inc. Devices, systems and methods for using and monitoring spinal implants
CN107003984A (en) * 2014-09-17 2017-08-01 卡纳里医疗公司 Equipment, system and method for using and monitoring Medical Devices
CN206491903U (en) * 2016-08-31 2017-09-15 北京爱康宜诚医疗器材有限公司 Intervertebral disk prosthesis
CN208573862U (en) * 2017-09-30 2019-03-05 四川大学华西医院 Artificial intelligence cervical intervertebral disc capable of recording pressure and movement

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050070913A1 (en) * 2003-09-29 2005-03-31 Milbocker Michael T. Devices and methods for spine repair
US20080019970A1 (en) * 2006-07-07 2008-01-24 Gorman James R Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures
CN101534751A (en) * 2006-09-15 2009-09-16 先锋外科技术公司 Joint arthroplasty devices having articulating members
CN101114531A (en) * 2007-07-23 2008-01-30 金连河 Automatic centering level system of tripod
US20090043391A1 (en) * 2007-08-09 2009-02-12 Spinalmotion, Inc. Customized Intervertebral Prosthetic Disc with Shock Absorption
US20100016972A1 (en) * 2008-07-17 2010-01-21 Spinalmotion, Inc. Artificial Intervertebral Disc Placement System
CN201757949U (en) * 2010-05-25 2011-03-09 上海中医药大学附属岳阳中西医结合医院 Semi-on-body biomechanical model of cervical structure simulating extensor muscles of posterior neck
US20130261503A1 (en) * 2012-03-31 2013-10-03 Jason T. Sherman System and method for validating an orthopaedic surgical plan
CN103006356A (en) * 2013-01-07 2013-04-03 刘小勇 Bionic type hydraulic movable artificial vertebral body
US20150039089A1 (en) * 2013-07-31 2015-02-05 Globus Medical, Inc. Artificial Disc Devices and Related Methods of Use
US20170196508A1 (en) * 2014-06-25 2017-07-13 Canary Medical Inc. Devices, systems and methods for using and monitoring spinal implants
CN107003984A (en) * 2014-09-17 2017-08-01 卡纳里医疗公司 Equipment, system and method for using and monitoring Medical Devices
CN104546229A (en) * 2015-01-19 2015-04-29 南京航空航天大学 Artificial cervical intervertebral disc with ultrahigh activity type chamfering U-shaped structure
CN204839838U (en) * 2015-06-23 2015-12-09 深圳兰度生物材料有限公司 Artifical neck intervertebral disc false body
US20170173326A1 (en) * 2015-12-22 2017-06-22 Ecole Polytechnique Federale De Lausanne (Epfl) System for selective spatiotemporal stimulation of the spinal cord
CN105534623A (en) * 2016-01-12 2016-05-04 四川大学华西医院 Bionic artificial intervertebral disc
CN105708584A (en) * 2016-01-18 2016-06-29 无锡宝通医疗投资有限公司 Integral bionic cervical disc prosthesis
CN105726278A (en) * 2016-04-25 2016-07-06 四川乐彤科技有限公司 Intelligent cervical vertebra massage robot with multiple degrees of freedom
CN206491903U (en) * 2016-08-31 2017-09-15 北京爱康宜诚医疗器材有限公司 Intervertebral disk prosthesis
CN208573862U (en) * 2017-09-30 2019-03-05 四川大学华西医院 Artificial intelligence cervical intervertebral disc capable of recording pressure and movement

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
娄纪刚;刘浩;李元超;孟阳;杨运北;李会波;: "一种新型人工颈椎间盘置换的生物力学研究", 生物骨科材料与临床研究 *
胡孔和;吴强;李康华;席新华;卢海波;李雄;陈立科;王斌;: "人工颈椎间盘置换术后邻近下位关节突关节压力变化的生物力学研究", 中国临床解剖学杂志 *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108969162A (en) * 2018-07-27 2018-12-11 深圳清华大学研究院 A kind of intervertebral motion retaining device
CN111821073A (en) * 2020-08-20 2020-10-27 四川大学华西医院 Orthopedic implant system and monitoring method for monitoring activity posture and stress changes
CN111839834A (en) * 2020-08-20 2020-10-30 四川大学华西医院 Intelligent uncinate vertebra joint stress monitoring system and method
CN111938881A (en) * 2020-08-20 2020-11-17 四川大学华西医院 Intelligent intervertebral disc system and monitoring method capable of monitoring active posture and stress
CN111973324A (en) * 2020-08-20 2020-11-24 四川大学华西医院 Orthopedic implant system based on stress self-adaption controllable adjustment and control method thereof
CN111973324B (en) * 2020-08-20 2022-11-11 四川大学华西医院 Orthopedic implant system based on stress adaptive and controllable adjustment and its control method
CN111821073B (en) * 2020-08-20 2023-02-28 四川大学华西医院 Orthopedic implant system for monitoring activity posture and stress change thereof and monitoring method
CN111938881B (en) * 2020-08-20 2023-02-28 四川大学华西医院 Intelligent intervertebral disc system and monitoring method capable of monitoring activity posture and stress
CN112294502A (en) * 2020-10-30 2021-02-02 四川大学华西医院 Assembly type total intervertebral disc prosthesis based on 3D printing technology and manufacturing method thereof
CN113124744A (en) * 2021-04-20 2021-07-16 电子科技大学 Intelligent intervertebral trial mold, implant and control method
CN115281900A (en) * 2022-08-17 2022-11-04 四川大学华西医院 Automatic adjusting system for rotation center of intervertebral disc prosthesis
CN115281900B (en) * 2022-08-17 2024-06-25 四川大学华西医院 Automatic rotation center adjusting system for intervertebral disc prosthesis

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