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CN107736900A - A kind of dual transducers intravascular ultrasound imaging device - Google Patents

A kind of dual transducers intravascular ultrasound imaging device Download PDF

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Publication number
CN107736900A
CN107736900A CN201711097897.4A CN201711097897A CN107736900A CN 107736900 A CN107736900 A CN 107736900A CN 201711097897 A CN201711097897 A CN 201711097897A CN 107736900 A CN107736900 A CN 107736900A
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CN
China
Prior art keywords
transducers
ultrasonic
imaging device
intravascular ultrasound
ultrasound imaging
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711097897.4A
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Chinese (zh)
Inventor
邱维宝
苏敏
张利宁
郑海荣
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Priority to CN201711097897.4A priority Critical patent/CN107736900A/en
Publication of CN107736900A publication Critical patent/CN107736900A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

The present invention provides a kind of dual transducers intravascular ultrasound imaging device, ultrasonic probe including conduit and positioned at catheter proximal end, the conduit includes pillar, metal hose and coaxial cable, the ultrasonic probe is located in the pillar, the ultrasonic probe includes two ultrasonic transducers, described two back-to-back settings of ultrasonic transducer, while or timesharing send ultrasonic acoustic beam and be imaged, described two ultrasonic transducers have common back sheet.The device of the present invention, including two high frequency list element transducers, two transducers can carry out ultrasonic wave transmitting and reception simultaneously during work, can obtain more intravascular tissue information.Meanwhile two ultrasonic transducers of the invention share back sheet, can greatly reduce the thickness of the transducer of sandwich construction, will greatly improve the practicality of device.

Description

A kind of dual transducers intravascular ultrasound imaging device
Technical field
Present invention relates in general to medical ultrasound image field, more particularly to a kind of dual transducers intravascular ultrasound imaging to fill Put.
Background technology
Atherosclerosis is a kind of higher angiocardiopathy of fatal rate, and it is to send out to have a significant feature It is not easy to be diagnosed discovery before disease.Its potential pathomechanism of more than 75% acute coronary syndrome is demonstrated as artery congee Sample plaque is broken, and therefore, detection and the patch for characterizing easy fracture are most living in cardiology and biomedical imaging research One of field of jump.
Has the lesion situation that plurality of medical imaging technique can be used for diagnosing vascular atherosclerosis at present.Blood vessel is made Shadow technology is to detect the Main Means of vascular atherosclerosis patch now, for determining that atherosclerotic blood vessel is narrow Position and degree.Contrast agent is rapidly injected among blood vessel by it under X-ray irradiation, because contrast agent absorbs X-ray and then can be real Now develop.The blood flow containing contrast agent is can see from the result of development, so as to understand the change of the physiology of blood vessel and dissection Change.Angiography is a kind of method of of great value diagnosis relevant vascular diseases, but it is only capable of providing and filled by contrast agent The tube chamber profile filled out, and the lesion nature and degree of display tube wall are unable to, most vulnerable plaque angiogram in blood vessel Technology for detection does not come out.
Medical ultrasound image technology is so that its is noninvasive, radiationless, real-time is good, instrument higher to soft tissue taste uses Convenient, lower-price characteristic, turn into diagnostic techniques irreplaceable in modern medicine imaging, turn into clinical a variety of diseases at present The prefered method of disease diagnosis.
Intravascular ultrasound (Intravascular ultrasound, IVUS) imaging technique is special in medical ultrasound image A kind of special imaging technique applied to angiocardiopathy detection.The technology utilizes the miniature ultrasonic probe installed in catheter tip The position that (or probe) is inserted into suspected lesion in human vas carries out two-dimentional imaging of tissue.It not only can be with real-time display blood vessel The form of inwall, but also can be analyzed by tissue plane and lesion size is measured with three-dimensional reconstruction, to understand in depth The form and function of vascular lesion provide the new visual field, while also provide and more accurately and reliably believe for clinical diagnosis and treatment Breath.Intravascular ultrasound imaging technology can also primarily determine that athero- hard in addition to it can show tube chamber form and vascular wall information Change the tectology feature of patch;Meanwhile pass through accurate quantitative analysis, measurement blood vessel diameter, cross-sectional area and narrow journey Degree, the not detectable early atherosclerosis lesion of recognizable angiogram, the borderline lesion especially shown to angiogram, Intravascular ultrasound imaging technology can carry out accurate quantitative analysis to it, determine its stenosis and lesion type, to assist to face The selection of bed therapeutic scheme.Intravascular ultrasound imaging technology also has extremely important in terms of Percutantnoeus coronary intervention formula treatment is instructed Application value.Because the technology can accurately react internal blood vessel pattern, lesion property and the order of severity situations such as, So as to provide foundation, such as selection suitable support of size etc. for the correct therapeutic strategy of selection.Intravascular ultrasound imaging simultaneously Whether whether evaluation of the technology available for postoperative support therapeutic effect, such as stent-expansion abundant, completely adherent, uniform Deploy and lesion etc. is completely covered, be advantageous to find in time and correct existing some problems after stenter to implant, to reach optimal Interventional therapeutic effect.
Intravascular ultrasound imaging technology is a kind of non-invasive ultrasonic technique and what invasive microcatheter technology was combined makes The medical imaging technology that the special conduit of ultrasonic probe carries out is connected with end, tube wall that can be where lesions showed and athero- Patch, improve the accuracy of diagnosis.The intravascular ultrasound transducer used now, mainly high frequency planar list array element are intravascular super Sonic transducer and high-frequency ring array intravascular ultrasound transducer.
At present, traditional intravascular ultrasound catheter is generally the electronics of the mechanical conduit and linear array transducer of single element transducer Phased array conduit.
Mechanical conduit is driven by tail end of conduit connection slip ring, and transducer, in catheter proximal end, catheter length is typically in 1.5m Left and right, vascular bending easily produce bigger frictional force between conduit and pillar, cause the transducer of catheter proximal end uneven Even rotation, the easy distortion of ultrasonoscopy of acquisition, the definition and precision for causing imaging are deteriorated.
Electronically phased array conduit manufacture difficulty is big, and imaging system is complicated, and comparatively frequency is than relatively low, and imaging resolution is not It is high.
In view of this, it is necessary to a kind of new intravascular ultrasound imaging device.
The content of the invention
For above-mentioned the deficiencies in the prior art, the invention provides a kind of dual transducers intravascular ultrasound imaging device, phase For standard machinery conduit, angle compensation can be carried out, imaging is more stable, contributes to doctor to carry out more accurate diagnosis;Also, Two transducers can work simultaneously, therefore can be imaged two width figures with once rotation, therefore can increase substantially ultrasound The frame frequency of imaging.
The invention provides a kind of dual transducers intravascular ultrasound imaging device, including conduit and the ultrasound positioned at catheter proximal end Probe, the ultrasonic probe are located in the conduit, and the ultrasonic probe includes two ultrasonic transducers, and described two ultrasounds are changed Can the back-to-back setting of device, while or timesharing send ultrasonic acoustic beam and be imaged, wherein described two ultrasonic transducers have it is common Back sheet.
Preferably, described two ultrasonic transducers are hierarchy, including the first matching layer, the first piezoelectric layer, back sheet, Second piezoelectric layer and the second matching layer.
Preferably, the matching layer of each ultrasonic transducer is one layer of matching layer or multi-layer Matched layer.
Preferably, the ultrasonic transducer is single array element planar transducer, single array element focused transducer, and more array element planes are changed Can device or more array element focused transducers.
Preferably, the central frequency range of the ultrasonic transducer is 15MHz~120MHz.
Preferably, the centre frequency of described two ultrasonic transducers is identical or different.
Preferably, the ultrasonic probe has shell, and described two ultrasonic transducers are arranged in the shell, described outer Shell is hollow cylindrical structure, and diameter range is 0.4 millimeter -3 millimeters.
Preferably, there are two openings being oppositely arranged, described two ultrasounds in the side wall of the shell of the ultrasonic probe Transducer carries out ultrasonic wave transmitting and reception by described two openings respectively.
Preferably, the conduit includes pillar, metal hose and coaxial cable, the back sheet of the ultrasonic transducer With groove, the negative line of the coaxial cable is connected in the groove with described by lining.
Preferably, the material of the piezoelectric layer is piezoelectric ceramics, monocrystalline piezoelectric material, piezo-electricity composite material, PVDF materials Or other piezoelectrics.
Preferably, the imaging device also includes connector, and one end of the connector is connected with the conduit, the other end Connection imaging system and rotation withdraw device, are withdrawn for signal transmission and ultrasonic probe rotation.
Beneficial effects of the present invention:
The dual transducers intravascular ultrasound imaging device of the present invention, including two high frequency list element transducers, two during work Individual transducer can carry out ultrasonic wave transmitting and reception simultaneously, can obtain more intravascular tissue information.In addition, the present invention Two ultrasonic transducers share back sheet, can greatly reduce the thickness of the transducer of sandwich construction.The thickness of transducer chip The size of intravascular ultrasound catheter is directly affected, chip is thinner, and conduit diameter is smaller, and supersonic imaging device can be more tiny Detected in blood vessel, improve the practicality of the present apparatus.
Brief description of the drawings
Fig. 1 is the structural representation of the dual transducers intravascular ultrasound imaging device of the present invention.
Fig. 2 is catheter proximal end (ultrasound imaging probe) structure in the dual transducers intravascular ultrasound imaging device of the present invention Schematic diagram.
Fig. 3 is the structural representation of the ultrasonic transducer in the dual transducers intravascular ultrasound imaging device of the present invention, its In (a) be transducer (side) and coaxial cable connection diagram, (b) is the front schematic view of transducer.
Fig. 4 is the dual transducers operating diagram in the dual transducers intravascular ultrasound imaging device of the present invention.
Embodiment
The specific embodiment of the present invention is illustrated below in conjunction with the accompanying drawings.Specific reality of the invention described below Apply in example, some very specific technical characteristics are described for better understanding of the present invention, but it will be apparent that for For those skilled in the art, these not all technical characteristics are all the essential features for realizing the present invention.Under Some specific embodiments of the invention described by text are some exemplary specific embodiments of the present invention, its should not by regarding For limitation of the present invention.In addition, in order to avoid making the present invention become indigestion, do not carried out for some known technologies Description.
Fig. 1 is the dual transducers intravascular ultrasound imaging apparatus structure schematic diagram of the present invention.As shown in figure 1, the present invention Intravascular ultrasound imaging device includes connector 1, conduit 2 and ultrasonic probe 3.One end of connector 1 is connected with conduit 2, another End connection imaging system and rotation withdraw device (not shown), are withdrawn for signal transmission and ultrasonic probe rotation.On connector 1 With valve 11, valve 11 is used to, to saline injection in ultrasound catheter, extrude the air in conduit, and be used as ultrasonic coupling Agent uses.Conduit 2 has pillar 21, metal hose 22 and transducer cable (coaxial cable) 23 successively from outside to inside, it may have The function that transmission signal and probe are withdrawn, and conduit 2 also has the devices (not shown) such as seal wire 24 (see Fig. 2) and locating ring, Can the location of position transducer, and guiding transducer moves in the blood vessels.Ultrasonic probe 3 is located at the front end of conduit 2 (i.e. one end away from connector 1), for carrying out ultrasonic imaging.
It is the catheter proximal end structural representation i.e. ultrasound in dual transducers intravascular ultrasound imaging device of the invention such as Fig. 2 The structural representation of imaging probe.As shown in Fig. 2 ultrasonic probe 3 has shell 31, and two be fixed in shell 31 change Can device 4.Two 4 back-to-back settings of ultrasonic transducer, while or timesharing send ultrasonic acoustic beam and be imaged.Shell 31 be copper or its The shell of his metal material.Transducer 4 (transducer chip) is fixed in shell 31 using bio-compatible glue.Specifically, it is whole Individual ultrasonic probe 3 is located in pillar 21, and metal hose 22 is fixed on a side of the shell 31.During work, ultrasonic probe 3 revolves Turn, pillar 21 and seal wire 24 remain stationary as.
In the present invention, the shell 31 of ultrasonic probe 3 is hollow cylindrical structure, a diameter of 0.4 millimeter -3 millimeters.Ultrasound is visited There are two openings 32 being oppositely arranged, two ultrasonic transducers 4 pass through two openings 32 respectively in the side wall of first 3 shell 31 Carry out ultrasonic wave transmitting and reception.In other implementation, probing shell 31 can also be the structure of other shapes.
Describe the structure of two ultrasonic transducers in detail with reference to Fig. 3.In the present invention, transducer 4 can be single array element Planar transducer, single array element focused transducer, more array element planar transducers or more array element focused transducers.As shown in Fig. 3 (b), Two ultrasonic transducers 4 are hierarchy, including the first matching layer 41, the first piezoelectric layer 42, share back sheet 43, the second piezoelectricity The matching layer 45 of layer 44 and second.Matching layer 41,45 and back sheet 43 are conductive material.The material of piezoelectric layer is piezoelectric ceramics, pressure Electric monocrystal material, piezo-electricity composite material, PVDF materials or other piezoelectrics.In the present invention, the first of two ultrasonic transducers 4 The quantity of matching layer and the second matching layer can be respectively one or more layers.Structure shown in Fig. 3 (b) is the first matching layer and the Two matching layers are respectively the situation of one layer of matching layer.In the embodiment that matching layer is respectively two layers, two ultrasonic transducer bags Include the first matching layer, the second matching layer, the first piezoelectric layer, back sheet, the second piezoelectric layer, the 3rd matching layer and the 4th matching layer.
As shown in Fig. 3 (a), two electrode line 23a of the coaxial cable 23 of conduit 2 are bonded respectively by electrically conducting adhesive 46 On the first matching layer 41, the second matching layer 45, it can also be connected by way of welding with matching layer;Coaxial cable 23 is born Polar curve 23b is bonded on back sheet 43 by electrically conducting adhesive 46, can also be connected by way of welding with shared back sheet 43 Connect.In the present invention, two ultrasonic transducers have common back sheet 43.
The present invention shares back sheet by two ultrasonic transducers, can greatly reduce the thickness of the transducer of sandwich construction Degree.Because intravascular ultrasound imaging device device is very high to thickness requirement, reduce the reality that transducer thickness will greatly improve device The property used.Only about 300 microns of the thickness of the shared back sheet of two transducers of the present invention, and have respectively certainly in two transducers In the case of oneself back sheet, its back sheet adds up about 600 microns.The thickness of transducer chip directly affects intravascular ultrasound The size of conduit, chip is thinner, and conduit diameter is smaller, and supersonic imaging device can be detected in more tiny blood vessel, be carried The high practicality of the supersonic imaging device of the present invention.
In a further preferred embodiment, the shared back sheet 43 of ultrasonic transducer also has groove 43a, coaxial cable Negative line 23b is connected in the groove by bonding agent 46 with back sheet 43.This structure can cause the lead of transducer to connect Connect more reliable.
In the present invention, the centre frequency of two ultrasonic transducers 4 can be with identical or different, the center of two ultrasonic transducers Frequency range is 15MHz~120MHz.
Fig. 4 is the dual transducers operating diagram in the dual transducers intravascular ultrasound imaging device of the present invention.As schemed Show, popped one's head in by rotary ultrasonic, two transducers 4 around the shell of ultrasonic probe central axis, while or timesharing send it is super Several Shu Jinhang alliterations beam image forming jobs.By the dual transducers structure in the present invention, two transducers work simultaneously to be surpassed Acoustic emission and reception, more intravascular tissue information can be obtained.
Although according to preferred embodiment, the present invention is described, exist fall into the scope of the invention it Interior change, displacement and various replacement equivalents.It should also be noted that a variety of methods for realizing the present invention be present and be The optional mode of system.It is therefore intended that appended claims are construed to include within the spirit and scope of the invention All these changes, displacement and various replacement equivalents.

Claims (11)

1. a kind of dual transducers intravascular ultrasound imaging device, including conduit and the ultrasonic probe positioned at catheter proximal end, described Ultrasonic probe is located in the conduit, it is characterised in that
The ultrasonic probe includes two ultrasonic transducers, described two back-to-back settings of ultrasonic transducer, while or timesharing hair Ultrasonic acoustic beam is sent to be imaged,
Wherein, described two ultrasonic transducers have common back sheet.
2. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that described two ultrasounds are changed Can device be hierarchy, including the first matching layer, the first piezoelectric layer, the back sheet, the second piezoelectric layer and the second matching layer.
3. dual transducers intravascular ultrasound imaging device according to claim 2, it is characterised in that each ultrasound is changed The matching layer of energy device is one layer of matching layer or multi-layer Matched layer.
4. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that the ultrasonic transducer It is single array element planar transducer, single array element focused transducer, more array element planar transducers or more array element focused transducers.
5. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that the ultrasonic transducer Central frequency range be 15MHz~120MHz.
6. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that described two ultrasounds are changed The centre frequency of energy device is identical or different.
7. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that the ultrasonic probe tool There is shell, described two ultrasonic transducers are arranged in the shell, and the shell is hollow cylindrical structure, and diameter range is 0.4 millimeter -3 millimeters.
8. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that the ultrasonic probe There are two openings being oppositely arranged, described two ultrasonic transducers are carried out by described two openings respectively in the side wall of shell Ultrasonic wave is launched and received.
9. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that the conduit includes shield Pipe, metal hose and coaxial cable, the back sheet of the ultrasonic transducer have groove, the negative line of the coaxial cable It is connected in the groove with the back sheet.
10. dual transducers intravascular ultrasound imaging device according to claim 2, it is characterised in that the piezoelectric layer Material is piezoelectric ceramics, monocrystalline piezoelectric material, piezo-electricity composite material, PVDF materials or other piezoelectrics.
11. dual transducers intravascular ultrasound imaging device according to claim 1, it is characterised in that also including connector, One end of the connector is connected with the conduit, and other end connection imaging system and rotation withdraw device, are transmitted for signal Withdrawn with ultrasonic probe rotation.
CN201711097897.4A 2017-11-09 2017-11-09 A kind of dual transducers intravascular ultrasound imaging device Pending CN107736900A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108704682A (en) * 2018-05-29 2018-10-26 京东方科技集团股份有限公司 Micro-fluidic device and its driving method, microfluidic system
CN109646053A (en) * 2018-12-27 2019-04-19 深圳北芯生命科技有限公司 Intravascular ultrasound catheter
WO2019119429A1 (en) * 2017-12-22 2019-06-27 中国科学院深圳先进技术研究院 Dual-transducer compensation imaging method and ultrasonic imaging system
CN110141268A (en) * 2019-05-07 2019-08-20 天津大学 A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe
CN111407313A (en) * 2020-04-03 2020-07-14 深圳先进技术研究院 Ultrasonic transducer and ultrasonic imaging device
CN111419285A (en) * 2020-04-28 2020-07-17 深圳英美达医疗技术有限公司 Ultrasonic three-dimensional imaging catheter and three-dimensional scanning method thereof
CN113017780A (en) * 2021-03-02 2021-06-25 哈尔滨医科大学 Catheter system integrating ultrasonic imaging and rotational atherectomy of plaque in cavity
CN113057675A (en) * 2021-03-15 2021-07-02 慧威医疗科技(台州)有限公司 Imaging device and imaging method thereof, detection probe and endoscope system
CN114145713A (en) * 2021-11-30 2022-03-08 深圳先进技术研究院 Double-frequency endoscopic catheter and imaging device

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CN102512208A (en) * 2011-12-13 2012-06-27 苏州生物医学工程技术研究所 Intravascular forward-view/side-view integrated double-field-of-view ultrasonic imaging device and imaging method thereof
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Publication number Priority date Publication date Assignee Title
WO2019119429A1 (en) * 2017-12-22 2019-06-27 中国科学院深圳先进技术研究院 Dual-transducer compensation imaging method and ultrasonic imaging system
CN108704682A (en) * 2018-05-29 2018-10-26 京东方科技集团股份有限公司 Micro-fluidic device and its driving method, microfluidic system
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CN110141268A (en) * 2019-05-07 2019-08-20 天津大学 A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe
CN111407313A (en) * 2020-04-03 2020-07-14 深圳先进技术研究院 Ultrasonic transducer and ultrasonic imaging device
CN111419285A (en) * 2020-04-28 2020-07-17 深圳英美达医疗技术有限公司 Ultrasonic three-dimensional imaging catheter and three-dimensional scanning method thereof
CN111419285B (en) * 2020-04-28 2023-07-28 深圳英美达医疗技术有限公司 Ultrasonic three-dimensional imaging catheter and three-dimensional scanning method thereof
CN113017780A (en) * 2021-03-02 2021-06-25 哈尔滨医科大学 Catheter system integrating ultrasonic imaging and rotational atherectomy of plaque in cavity
CN113017780B (en) * 2021-03-02 2022-03-08 哈尔滨医科大学 Catheter system integrating ultrasonic imaging and rotational atherectomy of plaque in cavity
CN113057675A (en) * 2021-03-15 2021-07-02 慧威医疗科技(台州)有限公司 Imaging device and imaging method thereof, detection probe and endoscope system
CN114145713A (en) * 2021-11-30 2022-03-08 深圳先进技术研究院 Double-frequency endoscopic catheter and imaging device

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Application publication date: 20180227