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CN107692196A - It is a kind of that there are health products for removing vivotoxin function and preparation method thereof - Google Patents

It is a kind of that there are health products for removing vivotoxin function and preparation method thereof Download PDF

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Publication number
CN107692196A
CN107692196A CN201710675234.XA CN201710675234A CN107692196A CN 107692196 A CN107692196 A CN 107692196A CN 201710675234 A CN201710675234 A CN 201710675234A CN 107692196 A CN107692196 A CN 107692196A
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China
Prior art keywords
parts
vitamin
health products
extract
vegetables
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Pending
Application number
CN201710675234.XA
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Chinese (zh)
Inventor
黄添友
周俊岭
黄灿
刘国章
钟雄霖
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GUANGDONG JIUTIAN GREEN PHARMACEUTICAL CO Ltd
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GUANGDONG JIUTIAN GREEN PHARMACEUTICAL CO Ltd
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Priority to CN201710675234.XA priority Critical patent/CN107692196A/en
Publication of CN107692196A publication Critical patent/CN107692196A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/25Synthetic polymers, e.g. vinylic or acrylic polymers
    • A23L33/26Polyol polyesters, e.g. sucrose polyesters; Synthetic sugar polymers, e.g. polydextrose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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Abstract

The invention discloses a kind of health products for having and removing vivotoxin function and preparation method thereof.The health products, include the component of following masses part:20 40 parts of pectase, 18 36 parts of resistant dextrin, 16 32 parts of FOS, 4 16 parts of red yeast rice, 2.5 7.5 parts of konjaku flour, appropriate vitamin and natural flavouring.Scientific formula of the present invention is reasonable, and compatibility is original, and by analyzing indices such as formula pharmacology, the pharmacodynamics, the functional health product that can effectively remove vivotoxin is made.Health products of the present invention are evident in efficacy, convenient to take, have no toxic side effect, and to reduce the generation of cardio-cerebrovascular diseases and the death rate, the physical constitution for improving its people is significant.

Description

It is a kind of that there are health products for removing vivotoxin function and preparation method thereof
Technical field
The invention belongs to field of health care products, and in particular to a kind of to have the health products for removing vivotoxin function and its preparation Method.
Background technology
With the development of science and technology, medical level more and more higher;In particular with growth in the living standard, people's itself is good for Kang Yishi is increasingly concerned, but therefore the species of disease is not reduced but, the incidence of disease of disease also more and more higher.Study carefully Its reason be due to for a long time by air pollution, residues of pesticides, chemicals, junk food, and life stress, work strain and Bad life style, bring a large amount of toxin to human body and can not discharge, cause the generation of various major diseases.
So-called toxin be human body itself need not, metabolism can not be discharged smoothly, be trapped in inside of human body and human body The material that can not voluntarily dissolve.Human toxin includes that inherent toxin is (such as caused by body metabolism:Low-density lipoprotein, fat Fat, homocysteine, free radical, stool, uric acid, lactic acid etc.) and external toxin (refer to air pollution, residues of pesticides, chemical drugs Exceeded heavy metal, junk food etc. in preservative, cosmetics in product, food).If these toxin can not discharge in time, Accumulate over a long period and be deposited on different organs, serious disease will be led to.As cholesterol is too high, do not excrete in time, it is easily heavy Product makes narrowed blood vessels, causes the generation of the diseases such as hypertension and artery sclerosis on vascular wall.Stool is human body intestinal canal toxin root Source, body can be invaded again by re-absorbed toxin, reduce body immunity.As the famous health expert An Delieye of Russia Described in husband:" the main reason for all diseases and root, in that the human body of human body has accumulated various toxin different levels are stagnant ".Cause This toxin expelling is that the mankind secure good health the approach of most crux.
The content of the invention
There are health products for removing vivotoxin function and preparation method thereof it is an object of the invention to a kind of.
The technical solution used in the present invention is:
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:Pectase 20-40 Part, resistant dextrin 18-36 parts, FOS 16-32 parts, red yeast rice 4-16 parts, konjaku flour 2.5-7.5 parts, appropriate vitamin And natural flavouring.
Preferably, vitamin includes vitamin C, vitamin B6, folic acid, vitamin B12
Preferably, vitamin C 300-500g, vitamin B are added in health products described in every 60kg61-1.5g, folic acid 250-500mg, vitamin B12 20-60mg。
Preferably, natural flavouring includes steviol glycoside, citric acid, natural fruit and vegetables extract.
Preferably, steviol glycoside 60-120g, citric acid 150-450g, natural fruit and vegetables are added in health products described in every 60kg Extract 15-45g.
Preferably, natural fruit and vegetables extract include Fragaia ananassa Duchesne extract, cider concentrated extract, mango concentrated extract, Orange juice concentrated extract.
Preferably, the health products, the component of following masses part is included:Pectase 25-35 parts, resistant dextrin 22-32 Part, FOS 19-29 parts, red yeast rice 7-13 parts, konjaku flour 3.5-6.5 parts, vitamin C 350-450g, vitamin B6 1.15-1.4g, folic acid 300-450mg, vitamin B12It is 30-50mg, steviol glycoside 75-105g, citric acid 200-400g, natural Fruits and vegetables extract 20-40g.
Preferably, the health products, the component of following masses part is included:It is 30 parts of pectase, 29 parts of resistant dextrin, oligomeric 25 parts of fructose, 10 parts of red yeast rice, 5 parts of konjaku flour, vitamin C 400g, vitamin B61.32g, folic acid 360mg, vitamin B12 39mg, steviol glycoside 90g, citric acid 300g, natural fruit and vegetables extract 30g.
Preferably, the health products, dosage form include tablet, capsule, granule or oral liquid.
A kind of preparation method with the health products for removing vivotoxin function, comprises the following steps:
Each component is weighed according to the proportioning described in any of the above-described;
By citric acid, natural fruit and vegetables extract, steviol glycoside, folic acid, vitamin B6, vitamin B12, vitamin C and resistance Dextrin is mixed evenly, and obtains just mixed material;
Red yeast rice, FOS, pectase, konjaku flour are well mixed, just mixed material is added, is well mixed;
Different formulations is made as needed, after the assay was approved, is packaged to be finished product.
The pharmacology of primary raw material, the property of medicine are as follows in inventive formulation:
Pectase:For the product after fruit, fermented vegetable.
Raw material pectase in the present invention is that the fruits and vegetables such as selected blueberry, pomegranate are raw material.After squeezing, by biology Zymolysis technique is fully digested fresh fruit, is made the abundant release of nutriment in fruit, is advantageous to the efficient of microorganism Fermentation;Efficient dominant bacteria is filtered out in traditional ferment zymotic fluid by genetic chip triage techniques again, passes through probiotics Multi-biological fermentation technique, the effective biologic ferment effect for controlling microorganism.Obtain rich in vitamin C, vitamin E, bear Fruit glucoside, protein, anthocyanin, acetic acid, prebiotics, FOS, amino acid, vitamin, trace element, organic acid, biological ferment The pectase raw material of element etc..The pectase major function includes:With protection capillary and oxidation resistant effect;Ease constipation Defaecation, toxin-expelling and face nourishing;Maintain body fluid acid-base balance;Blood is purified, is stimulated circulation;Immune cell activated, improve immune work( Energy;Eyesight is protected, alleviates kopiopia and other effects.
Red yeast rice:Existing more than the 1000 years production of red yeast rice and applicating history in China, with rice such as long-grained nonglutinous rice, japonica rice, glutinous rice For raw material, formed with monascus ruber fermentation.Numerous studies find that it contains the active matter that can significantly inhibit internal cholesterol biosynthesis Matter Monacolin K, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) is non-in the chemical constitution of the compound and organism It is often similar, and HMG-CoA reductase is the key enzyme of control volume inner cholesterol aggregate velocity, therefore Monacolin K classes Compound effectively can reduce or block endogenous cholesterol in clinical practice as the competitive inhibitor of HMG-CoA reductase Synthesis.In addition, Monacolin K also have regulating blood lipid action, research confirms that it has the Apo for reducing hyperlipidemia patient AI is horizontal, and rise Apo B are horizontal, correcting lipid disorder, so as to play regulating blood lipid action.
Konjaku flour:The main component of konjaku is Glucomannan, is the food of a kind of low calorie, low-protein, high dietary-fiber Product, and the ten several amino acid and trace element rich in needed by human body.Konjaku glucomannan can effectively suppress small intestine and courage is consolidated The absorption of the lipolysis material such as alcohol, bile acid, promote fat to excrete, reduce fat, cholesterol enters blood, reduction blood Triglyceride and cholesterol total amount in clear, therefore preventing hypertension, high fat of blood and angiocardiopathy can be played a part of.In addition, The distinctive beam aquagel fibre of konjaku, heavy metal element and dietotoxicity material in enteron aisle can be promoted to exclude rapidly, reduced harmful The time of contact of material and intestinal wall, absorption of the enteron aisle to these materials is prevented, remove the retentate in stomach, intestines, gall-bladder, effectively drop The probability that harmful bacteria infects in low colon, rectum, play the effect for excluding intestines poison.
Resistant dextrin is process by starch, is that the indigestibility composition industrial technology extraction process that will bake dextrin is simultaneously smart A kind of Low Caloric Polydextrose formed is refined, belongs to low molecule water-soluble dietary fiber.It is former as a kind of soluble food low in calories Material, the vast potential for future development having in the food industry.
FOS is also known as fructooligosaccharide, is to pass through the fruit in β (2-1) glycosidic bond and sucrose by 1~3 fructosyl Glycosyl combines the mixture of ketose, Nystose and the GF4 of generation etc..FOS, which removes, has general utility functions Outside the physicochemical properties of oligosaccharide, most noticeable physiological property is that it can be obviously improved microbial population ratio in enteron aisle Example, it is the activation and proliferation factor of enteral Bifidobacterium, can reduce and suppress the generation of enteral corrupt substance, suppresses harmful bacteria Growth, adjust enteron aisle inner equilibrium;The absorption and utilization of trace elements iron, calcium can be promoted, to prevent osteoporosis;It can reduce Hepatotoxin, the organic acid of anticancer can be generated in intestines, there is significant preventing cancer function.
The present invention gets up the collocation of pectase, resistant dextrin, FOS, red yeast rice and konjaku flour, wherein fruits and vegetables ferment Element, resistant dextrin, FOS, red yeast rice and konjaku flour are respectively provided with the toxin of purification blood and waste, stimulated circulation Effect, is advantageous to the exclusion of stool, plays the effect for excluding intestines poison, while can also adjust the synthesis of cholesterol and superabundant fats And operating.Improve microbial population ratio in enteron aisle, promote the field planting of probiotics, reduce and suppress the production of enteral corrupt substance It is raw, suppress the growth of harmful bacteria, adjust enteron aisle inner equilibrium.
The present invention further includes VB using B family vitamin6, VB12, the metabolic response of folic acid regulation homocysteine, The VC that arranges in pairs or groups simultaneously contributes to anti-oxidant, anti-aging.And research data shows:Homocysteine often raises 5umol/L brains soldier Risk rise 59%, ischemic heart disease risk rise 32%.The harm of homocysteine is coup injury blood vessel, high blood It is the most important hazards of cerebral apoplexy that if pressure, which merges homocysteine,.Therefore, compounding supplement is suitable in inventive formulation Folic acid, the VB of amount6、VB12It is very important with VC for prevention cardiovascular and cerebrovascular disease.
In summary, functional health product formula of the invention, it is to have effectively to remove or reduce cholesterol, glycerine three The functional health product of blood toxicity and enterotoxin caused by the internal metabolism such as fat, homocysteine.
The beneficial effects of the invention are as follows:
Scientific formula of the present invention is reasonable, and compatibility is original, by analyzing indices such as formula pharmacology, the pharmacodynamics, system Vivotoxin (triglycerides, cholesterol, low-density lipoprotein, lipid peroxide, homocysteine, place can effectively be removed by obtaining Just functional health product etc.).It is evident in efficacy, it is convenient to take, have no toxic side effect, for reduce cardio-cerebrovascular diseases generation and The death rate, the physical constitution for improving its people are significant.
Embodiment
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:Pectase 20-40 Part, resistant dextrin 18-36 parts, FOS 16-32 parts, red yeast rice 4-16 parts, konjaku flour 2.5-7.5 parts, appropriate vitamin And natural flavouring.
Preferably, vitamin includes vitamin C, vitamin B6, folic acid, vitamin B12
Preferably, vitamin C 300-500g, vitamin B are added in health products described in every 60kg61-1.5g, folic acid 250-500mg, vitamin B12 20-60mg。
Preferably, natural flavouring includes steviol glycoside, citric acid, natural fruit and vegetables extract.
Preferably, steviol glycoside 60-120g, citric acid 150-450g, natural fruit and vegetables are added in health products described in every 60kg Extract 15-45g.
Preferably, natural fruit and vegetables extract include Fragaia ananassa Duchesne extract, cider concentrated extract, mango concentrated extract, Orange juice concentrated extract.
Preferably, the health products, the component of following masses part is included:Pectase 25-35 parts, resistant dextrin 22-32 Part, FOS 19-29 parts, red yeast rice 7-13 parts, konjaku flour 3.5-6.5 parts, vitamin C 350-450g, vitamin B6 1.15-1.4g, folic acid 300-450mg, vitamin B12It is 30-50mg, steviol glycoside 75-105g, citric acid 200-400g, natural Fruits and vegetables extract 20-40g.
Preferably, the health products, the component of following masses part is included:It is 30 parts of pectase, 29 parts of resistant dextrin, oligomeric 25 parts of fructose, 10 parts of red yeast rice, 5 parts of konjaku flour, vitamin C 400g, vitamin B61.32g, folic acid 360mg, vitamin B12 39mg, steviol glycoside 90g, citric acid 300g, natural fruit and vegetables extract 30g.
Preferably, the health products, dosage form include tablet, capsule, granule or oral liquid.
A kind of preparation method with the health products for removing vivotoxin function, comprises the following steps:
Each component is weighed according to the proportioning described in any of the above-described;
By citric acid, natural fruit and vegetables extract, steviol glycoside, folic acid, vitamin B6, vitamin B12, vitamin C and resistance Dextrin is mixed evenly, and obtains just mixed material;
Red yeast rice, FOS, pectase, konjaku flour are well mixed, adds in just mixed material, is well mixed;
Different formulations is made as needed, after the assay was approved, is packaged to be finished product.
Embodiment 1
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:
30 parts of pectase, 29 parts of resistant dextrin, 25 parts of FOS, 10 parts of red yeast rice, 5 parts of konjaku flour.
Then according to addition vitamin C 400g, vitamin B in every 60kg health products61.32g, folic acid 360mg, dimension life Plain B1239mg, steviol glycoside 90g, citric acid 300g, natural fruit and vegetables extract (Fragaia ananassa Duchesne extract or apple juice concentrate, awns Fruit concentrate or orange juice concentrate) 30g.
Production method is as follows:
1.1st, requirement, production space and equipment cleaning and sterilizing are managed by GMP.
1.2nd, weigh:Each component original, auxiliary material are weighed by formula ratio.
1.3rd, mix:
1.3.1 just mix material:First by citric acid, essence, steviol glycoside, folic acid, vitamin B6, vitamin B12, vitamin C Pour into mixer and stir with resistant dextrin.
1.3.2 red yeast rice, FOS, pectase, konjaku flour, are weighed first to be well mixed, just mixed material is added, puts Enter in mixer, start stirring 20 minutes.
1.4th, dispense:Granule is made, is wrapped per 10g mono-, after the assay was approved, packaging is got product.
Embodiment 2
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:
33 parts of pectase, 29 parts of resistant dextrin, 24 parts of FOS, 12 parts of red yeast rice, 4 parts of konjaku flour.
Then according to addition vitamin C 410g, vitamin B6 1.2g, folic acid in functional health product described in every 60kg 400mg, vitamin B1242mg, steviol glycoside 90g, citric acid 300g, natural fruit and vegetables extract (Fragaia ananassa Duchesne extract or cider Concentrate or mango concentrate or orange juice concentrate) 32g.
Preparation method is the same as embodiment 1.
Embodiment 3
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:
28 parts of pectase, 27 parts of resistant dextrin, 23 parts of FOS, 9 parts of red yeast rice, 6 parts of konjaku flour.
Then according to addition vitamin C 380g, vitamin B in health products described in every 60kg61.3g, folic acid 360mg, dimension Raw plain B1235mg, steviol glycoside 80g, citric acid 260g, natural fruit and vegetables extract (Fragaia ananassa Duchesne extract or apple juice concentrate, Or mango concentrate or orange juice concentrate) 35g.
Preparation method is the same as embodiment 1.
Embodiment 4
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:
27 parts of pectase, 28 parts of resistant dextrin, 25 parts of FOS, 10 parts of red yeast rice, 5 parts of konjaku flour.
Then according to addition vitamin C 370g, vitamin B in health products described in every 60kg61.1g, folic acid 360mg, dimension Raw plain B1232mg, steviol glycoside 83g, citric acid 280g, natural fruit and vegetables extract (Fragaia ananassa Duchesne extract or apple juice concentrate or Mango concentrate or orange juice concentrate) 32g.
Preparation method is the same as embodiment 1.
Embodiment 5
It is a kind of that there are the health products for removing vivotoxin function, include the component of following masses part:
35 parts of pectase, 30 parts of resistant dextrin, 26 parts of FOS, 10 parts of red yeast rice, 6 parts of konjaku flour.
Then according to addition vitamin C 420g, vitamin B in health products described in every 60kg61.35g, folic acid 380mg, Vitamin B1235mg, steviol glycoside 95g, citric acid 330g, natural fruit and vegetables extract (Fragaia ananassa Duchesne extract or cider concentration Thing or mango concentrate or orange juice concentrate) 35g.
Preparation method is the same as embodiment 1.
Functional health product prepared by embodiment is subjected to related experiment to confirm its effect.
Experiment 1, reduce homocysteine experiment
Zoopery
First, purpose:Confirming whether functional health product of the present invention has by zoopery reduces homocysteine Effect.
2nd, material:
1st, sample:The functional health product of embodiment 1, date of manufacture:20170111,10g/ bags.
2nd, animal:From male Wister rat, 200 ± 15g of body weight.
3rd, instrument and reagent:ELIASA, homocysteine detection kit, methionine.
3rd, method:
1st, prepared by animal model:From male Wister rat 60,200 ± 15g of body weight.After raising one week, start to 2% methionine solution is given to feed, 1 time a day, each 5ml, wherein having 10 to be only used as blank control does not feed methionine solution, continuously Two weeks.Blood is taken to survey homocysteine level (be then considered as higher than more than blank control group 5umol/L and model successfully).
2nd, feeding sample experiments:Successful rat will be modeled and be randomly divided into four groups, control group, low dose group, middle dose group, High dose group, every group 12 (blank group of modeling continues as blank control).
2.1st, low dose group:0.83g/kg.b.w, equivalent to 5 times of recommended daily dosage.
2.2nd, middle dose group:1.67g/kg.b.w, equivalent to 10 times of recommended daily dosage.
2.3rd, high dose group:3.34g/kg.b.w, equivalent to 20 times of recommended daily dosage.
Each concentration of sample needed for experiment is formulated with 50-60 DEG C of pure water dilution, once a day, every time with 5ml/ Kg.b.w gavages.Taken a blood sample after two weeks from rat aorta and survey content of homocysteine.
4th, result:
1st, homocysteine model is established:After Wister rat feedings one week, give 2% methionine solution and feed, Once a day, continuous two weeks, blood is taken to survey homocysteine level.It the results are shown in Table 1.
Table 1:Homocysteine model is established
The result of table 1 is shown:It is significantly raised with negative control group comparison model group homocysteine level.
2nd, influence of the functional health product of the present invention to homocysteine level
The functional health product for awarding the embodiment of the present invention 1 surveys each group homocysteine level after two weeks.It the results are shown in Table 2。
Table 2:Influence of the functional health product of the present invention to homocysteine level
The result of table 2 is shown:Compared with model group, all groups and model group all have significant difference.With low dose group phase Than middle dose group and high dose group have significant difference.The functional health product of the embodiment of the present invention 1 is confirmed according to result above Have the function that to reduce homocysteine.
Experiment 2, regulating blood lipid action animal experiment
1st, test objective:
Regulating blood lipid action of the functional health product to hyperlipemia rat of embodiment 1 is observed by animal experiment.
2nd, test material:
2.1st, sample:
The functional health product of embodiment 1, according to recommended amounts for 2 times a day, 1 bag, often wraps 10g every time, based on 60kg adults For 0.17g/kg.b.w, each concentration needed for experiment is formulated with 50-60 DEG C of pure water dilution.
2.2nd, dosage:
If high lipid food control group, normal diet control group and basic, normal, high three dosage groups, dosage is as follows respectively:
2.2.1, low dose group:0.83g/kg.b.w, equivalent to 5 times of recommended daily dosage.
2.2.2, middle dose group:1.67g/kg.b.w, equivalent to 10 times of recommended daily dosage.
2.2.3, high dose group:3.34g/kg.b.w, equivalent to 20 times of recommended daily dosage.
2.3rd, animal:
Male SD big white mouse, 183 ± 15g of body weight, are provided by Nanfang Medical Univ's Experimental Animal Center.And provide rat base Plinth feed meal and pellet.
2.4th, instrument and reagent:
2.4.1, instrument:The full automatic biochemical apparatus of Hitachi 7060.
2.4.2, reagent:Serum total cholesterol cholesterol oxidation enzyme process;Triglycerides glycerol-3-phosphate oxidase method; HDL-C uses the direct cholesterol oxidation enzyme process of two steps, and kit is provided by German Roche Holding Ag.
2.5th, tested material approach is given:Daily morning and afternoon is each once, gives tested material every time with 10ml/kg.b.w gavages.
3rd, test method:
3.1st, experimental animal is grouped:Set up normal diet control group, high lipid food control group, low dose group, middle dose group, 5 experimental groups of high dose group.
3.2nd, animal experiment:By 60 SD germline rats, wherein 12 (normal diet control group) is fed to basis daily Grain feed, remaining 48 are fed to high fat nutrient fodder (formula are daily:79% basal feed powder, 1% cholesterol, 10% yolk Powder and 10% lard, dried in 80 DEG C of baking ovens, the high fat nutrient fodder of strip is made).
Before tested material, serum total cholesterol (TC), triglycerides (TG) level are detected respectively, according to serum total cholesterol Level is randomly divided into normal diet control group, high lipid food control group and basic, normal, high test sample group.Experimental group and high fat are raised Material control group gives high lipid food, and normal diet control group is fed to base particle feed.Weigh weekly, according to body weight give by Thing, continue 30 days, after the 31st day weighs, take whole blood, separate serum, survey three blood lipid levels.
4th, result:
4.1st, influence of the functional health product of embodiment 1 to animal subject body weight, the results are shown in Table 3.
Table 3:Influence of the functional health product of the present invention to animal subject body weight
The result of table 3 is shown:The functional health product of embodiment 1 is given after 30 days, each body weight compared with control group, difference without Significant.
4.2nd, influence of the functional health product of embodiment 1 to animal subject serum total cholesterol (TC), the results are shown in Table 4.
Table 4:Influence of the functional health product of the present invention to total cholesterol level
The result of table 4 is shown:Functional health product of the present invention is given after 30 days, normal diet control group serum total cholesterol (TC) compared with high lipid food control group, serum total cholesterol is significantly raised, shows that hyperlipidemia model is set up;Each dosage group serum courage For sterol levels (TC) compared with high lipid food control group, serum total cholesterol has different degrees of reduction;As a result the present invention is shown Functional health product has the effect of reducing T-CHOL.
4.3rd, the functional health product of the present invention influence horizontal to animal subject serum triglyceride (TG), the results are shown in Table 5.
Table 5:Influence of the functional health product of the present invention to triglycerides
The result of table 5 is shown:The functional health product of embodiment 1 is given after 30 days, normal diet control group serum glycerine three For ester (TG) compared with high lipid food control group, serum triglyceride (TG) is significantly raised;Middle and high dosage group compares with high lipid food Group compares, and serum triglyceride (TG) has different degrees of reduction, the results showed that shadow of the product of the present invention to triglyceride levels Sound is positive findings.
4.4th, influence of the functional health product of the present invention to animal subject serum High Density Lipoprotein Cholesterol (HDL-C), It is shown in Table 6.
Table 6:Functional health product of the present invention gives the influence of HDL-C levels after tested material
The result of table 6 is shown:Functional health product of the present invention is given after 30 days, middle and high dosage group serum high-density LP Cholesterol (HDL-C) is more significantly raised than high lipid food control group.
5th, conclusion:
5.1st, the functional health product high dose group of embodiment 1 is compared with high lipid food control group, serum triglyceride drop It is low.High lipid food control group compares, and difference has significant (P<0.05).
5.2nd, functional health product serum High Density Lipoprotein Cholesterol (HDL-C) the high dose group of embodiment 1 is than high fat Feed control group raises, and compared with high lipid food control group, difference has significant (P<0.05).
According to the above results, according to《Function of health food assessment process and the method for inspection》Criterion, it was demonstrated that this The functional health product of invention has the function that to adjust animal lipid.
The effect experiment of functional health product of the present invention is taken in experiment 3, volunteer
Following experiments are carried out using the functional health product of the embodiment of the present invention 1.
1st, Lee XX, man, 56 years old, lives riverhead Yuancheng District.Often have palpitation, uncomfortable in chest, poor, dizziness of sleeping is forgetful to wait disease Shape, hospital diagnosis are coronary heart disease.Give the medicine of oral enteric aspirin, Betaloc, and reduction blood fat nearly 1 year, symptom Lose mitigation.Through recommending to use functional health product particle electuary of the present invention simultaneously, a daily sooner or later each bag (10g/ Bag), warm water is taken after mixing with liquid.After taking 2 courses for the treatment of, have palpitation, symptom uncomfortable in chest substantially mitigates, and sleep quality increases.
2nd, Liu XX, man, 55 years old, Heyuan City people from Yuancheng District.Find that blood fat and homocysteine are higher (total after having a medical check-up Cholesterol 5.42mmol/L, triglycerides 1.75mmol/L, LDL-C 3.23mmol/L, the Guang of serum homotype half 18 μm of ol/L of propylhomoserin), introduced through friend and use functional health product particle electuary of the present invention, respectively take a bag sooner or later daily (10g/ bags), after continuously taking one month, blood test indices are normal, and original the symptoms such as abdominal distension, constipation often occurs and disappeared Lose.
3rd, clock XX, man, 61 years old, lives Baiyun District, Guangzhou City.Often there is nervous, shortness of breath, uncomfortable in chest, have a chest pain, sleep once in a while Poor, the symptom such as constipation of dormancy.Blood test:T-CHOL 6.20mmol/L, LDL-C 4.12mmol/L, 20 μm of HDL-C 0.93mmol/L, triglycerides 1.75mmol/L, homocysteine ol/L.Use Functional health product particle electuary of the present invention, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with 50-60 DEG C of warm water. Blood test after taking one month:T-CHOL 6.00mmol/L, LDL-C 4.03mmol/L, high density fat 16 μm of protein cholesterol 0.98mmol/L, triglycerides 1.73mmol/L, homocysteine ol/L, clinical symptoms are obvious Mitigate.
4th, XX is opened, man, 42 years old, Heyuan City people from Dongyuan County, individual operator.Nervous, uncomfortable in chest, gas is often felt in readme in the recent period It is short, aggravated when working, sleep is poor, stool scleroma.Through recommending to take functional health product particle electuary of the present invention, daily Sooner or later each bag (10g/ bags), is taken after mixing with liquid, subjective symptoms mitigates after continuously taking one month, and does not occur intestines and stomach not with warm water The symptom such as suitable, stool are normal.
5th, woods XX, man, 52 years old, lives Yunfu, guangdong Province, certain secondary school teachers.Readme often feels nervous, uncomfortable in chest, passes through during sleep Normal chest, which is suppressed, feels bad, it is impossible to lies low, poor, slight Hypertension of sleeping, blood fat is high, and it is higher (21 μm of ol/L) to look into homocysteine. Through recommending to take functional health product particle electuary of the present invention, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with warm water. Subjective symptoms mitigates after continuously taking 1 month, and diet, sleep are normal, and stool is normally.
6th, X, man 58 years old, people from Guangzhou are thanked.Regular nervous, shortness of breath, sleep is poor, looks into T-CHOL 5.60mmol/L, low Higher (the 19.5 μm of ol/ of density lipoprotein-cholesterol 3.60mmol/L, triglycerides 1.75mmol/L homocysteines L).Through recommending to take functional health product particle electuary of the present invention, each one (10g/ bags) is wrapped sooner or later daily, use warm water It is taken after mixing with liquid.Subjective symptoms mitigates after continuously taking 1 month, and sleep is normal, and stool is normally.
7th, remaining XX, female, 51 years old, Foshan is lived.Readme often feels nervous, uncomfortable in chest, and frequent chest, which is suppressed, during sleep feels bad, Poor, the slight Hypertension of sleep, Hyperlipidemia (T-CHOL 5.63mmol/L, LDL-C 3.35mmol/L, glycerine Three ester 1.73mmol/L), it is higher (18.5 μm of ol/L) to look into homocysteine.Through recommending to take function of the present invention Sex-health products particle electuary, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with warm water.Subjective symptoms after continuously taking 1 month Mitigate, 15.6 μm of ol/L of check homocysteine.
8th, Lee XX, man, 63 years old, lives Guangdong Jiangmen city.Readme apoplexy more than 20 years, handicapped, left hand can not stretch out, Blood pressure 152mmHg/96mmHg, blood test:T-CHOL 6.00mmol/L, LDL-C 4.15mmol/L, 23 μm of triglycerides 1.96mmol/L, homocysteine ol/L.Through recommending to take functional health of the present invention Product particle electuary, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with warm water;Nine days green board Fu Shou recovering capsules are taken simultaneously, often It each 3 sooner or later.Subjective symptoms mitigates after continuously taking 1 month, and feeling relaxed is many on foot, and palm can also stretch out, and diet, sleep Dormancy makes moderate progress.
9th, king XX, man 48 years old, people from Guangzhou.Regular nervous, shortness of breath, sleep, which happens occasionally, uncomfortable in chest feels bad, it is impossible to lies low Phenomenon, blood pressure, Hyperlipidemia (T-CHOL 5.80mmol/L, LDL-C 3.56mmol/L, triglycerides 1.72mmol/L).Through recommending to take functional health product particle electuary of the present invention, each one (10g/ is wrapped sooner or later daily Bag), it is taken after mixing with liquid with warm water.Continuous subjective symptoms mitigation after taking 2 courses for the treatment of, diet, sleep are normal, and stool is normal.
10th, Xu XX, man, 53 years old, people from Guangzhou.Often feel within nearly 2 years that nervous, slightly activity is all felt very tried, rapid heart beat, gas It is short, the phenomenon uncomfortable in chest felt bad that happens occasionally of sleeping, look into 21.5 μm of ol/L of homocysteine.Through recommending to take institute of the present invention The functional health product particle electuary stated, each one wrap, be taken after mixing with liquid with warm water sooner or later daily.It is continuous take 1 month after feel it is nervous, The symptom mitigations such as rapid heart beat, 18.2 μm of ol/L of homocysteine, sleep is normal, and stool is normal.
11st, Peng X, man, 63 years old, people from Guangzhou, retired professor.Found after having a medical check-up blood fat (T-CHOL 5.68mmol/L, it is sweet Three ester 1.72mmol/L, LDL-C 3.60mmol/L of oil) and homocysteine (19.5 μm of ol/L) It is higher, introduced through friend and use particle electuary of the present invention, respectively take a bag sooner or later daily, blood after continuously taking one month Check that indices have different degrees of reduction, the disappearance of the symptoms such as abdominal distension, constipation often occurs in original.
12nd, old XX, man, 45 years old, Hunan Loudi City people.Blood fat (T-CHOL 5.45mmol/L, low-density are found after having a medical check-up Lipoprotein cholesterol 3.35mmol/L, triglycerides 1.75mmol/L) and homocysteine it is higher (19 μm of ol/L), warp Friend, which introduces, uses particle electuary of the present invention, a bag is taken before sleeping every night, blood test after continuously taking one month Indices are normal.
13rd, woods XX, man, 50 years old, certain secondary school teachers.Nervous, rapid heart beat is often felt in the recent period, slightly activity is all felt very tried, Sleep is poor, and sleep happens occasionally phenomena such as feeling bad uncomfortable in chest, looks into 19.5 μm of ol/L of homocysteine.Through recommending to take this hair Bright described functional health product particle electuary, each one wrap, be taken after mixing with liquid with warm water sooner or later daily.Felt after continuously taking 1 month The symptom mitigations such as nervous, rapid heart beat, 16.5 μm of ol/L of homocysteine, the phenomenon for difference of sleeping make moderate progress.
14th, XX, man 48 years old, people from Guangzhou are thanked.Blood fat (T-CHOL 5.62mmol/L, triglycerides are found after having a medical check-up 1.73mmol/L, LDL-C 3.53mmol/L) and homocysteine it is higher (18 μm of ol/L), through friend Friend, which introduces, uses functional health product particle electuary of the present invention, and a bag (10g/ bags) is taken before sleeping every night, continuous clothes Normal with blood test indices after one month, often there are the symptoms such as abdominal distension, constipation and disappeared in original.
15th, remaining XX, female, 53 years old, people from Guangzhou, certain university teaching and administrative staff.Blood fat (T-CHOL 5.63mmol/ is found after having a medical check-up L, triglycerides 1.72mmol/L, LDL-C 3.53mmol/L) and homocysteine (18 μm of ol/ L it is) higher, introduced through friend and use functional health product particle electuary of the present invention, a bag of being taken after mixing it with water before sleeping every night (10g/ bags), blood test indices are normal after continuously taking one month, and stool is normal.
16th, Lee XX, man, 55 years old, people from Guangzhou, certain company clerk.Regular nervous, shortness of breath, sleep happen occasionally uncomfortable in chest Feel bad, it is impossible to the phenomenon to lie low.Through recommending to take functional health product particle electuary of the present invention, each one wrap sooner or later daily (10g/ bags), is taken after mixing with liquid with warm water.Subjective symptoms mitigates after continuously taking 1 month, and diet, sleep are normal, and stool is normally.
17th, king XX, man, 63 years old, people from Guangzhou.Often feel to have palpitation over nearest one month, uncomfortable in chest, rapid heart beat, sleep compared with Phenomena such as poor.Through recommending to take functional health product particle electuary of the present invention, each one (10g/ bags) is wrapped sooner or later daily, used Warm water is taken after mixing with liquid.Subjective symptoms substantially mitigates after continuously taking 1 month, and poor phenomenon of sleeping makes moderate progress.
18th, Xu XX, man, 48 years old, Hubei people from Wuhan City.Closely feel nervous, uncomfortable in chest, rapid heart beat sometimes over the past half year, particularly Feel heavier after doing some manual labors, sleep is poor.Have a blood test fat (T-CHOL 5.65mmol/L, triglycerides 1.73mmol/ L, LDL-C 3.60mmol/L) and homocysteine it is higher (18.5 μm of ol/L), introduced through friend Using functional health product particle electuary of the present invention, a bag (10g/ bags) is taken before sleeping every night, continuously takes one Blood test indices have different degrees of reduction after month, have palpitation, be uncomfortable in chest, the symptom such as rapid heart beat is obviously improved.
19th, Peng X, man, 56 years old, people from Guangzhou.Oneself feel to occur now and then in the recent period nervous, uncomfortable in chest, blood fat is found after having a medical check-up (T-CHOL 5.56mmol/L, triglycerides 1.71mmol/L, LDL-C 3.54mmol/L) and serum are same Type cysteine is higher (19 μm of ol/L).Introduced through friend and use functional health product particle electuary of the present invention, daily Take a bag (10g/ bags) before sleeping at night, blood test indices are normal after continuously taking one month, it is former often occur abdominal distension, The symptoms such as constipation disappear, and feel that the state of mind is preferable.
20th, Wu XX, man, 56 years old, Xiangtan, Hunan Province people from city.Readme often feels nervous, uncomfortable in chest in this year, heartbeat is very fast, Sleep is poor, stool scleroma.Through recommending to take functional health product particle electuary of the present invention, each one wrap sooner or later daily (10g/ bags), is taken after mixing with liquid with warm water, and subjective symptoms substantially mitigates after continuously taking 2 courses for the treatment of, and phenomena such as poor of sleeping substantially mitigates, Stool is normal.
21st, multitude XX, female, 53 years old, Hunan Loudi City secondary school teachers.Readme often feels nervous, uncomfortable in chest, and sleep is poor, greatly Just harden, Hyperlipidemia (T-CHOL 5.65mmol/L, triglycerides 1.72mmol/L, LDL-C 3.60mmol/L).Through recommending to take particle electuary of the present invention, each one (10g/ bags) is wrapped sooner or later daily, adjusted with warm water Clothes, subjective symptoms mitigates after continuously taking 2 courses for the treatment of, and the phenomenon for difference of sleeping makes moderate progress, and stool is normal.
22nd, thank to XX, man, 48 years old, people from Guangzhou.Nervous, uncomfortable in chest, shortness of breath is often felt in readme, is aggravated when working, and sleeps Difference, stool scleroma.Looking into Hyperlipidemia, (T-CHOL 5.73mmol/L, triglycerides 1.76mmol/L, low-density lipoprotein courage are consolidated Alcohol 3.65mmol/L), homocysteine is higher (19 μm of ol/L).Through recommending to take functional health of the present invention Product particle electuary, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with 50-60 DEG C of warm water, disease is felt after continuously taking 2 courses for the treatment of Shape mitigates, and does not occur the symptoms such as gastrointestinal discomfort, and stool is normal.
23rd, remaining XX, female, 50 years old, people from Guangzhou, certain university teaching and administrative staff.Nervous, uncomfortable in chest, shortness of breath is often felt in readme, when working Aggravate, sleep is poor, stool scleroma, there is history of hypertension.Through recommending to take functional health product particle electuary of the present invention, often Each one wraps (10g/ bags) sooner or later for it, is taken after mixing with liquid with warm water, and subjective symptoms mitigates after continuously taking 2 courses for the treatment of, and stool is normal, sleep Poor phenomenon makes moderate progress.
24th, Hu XX, man, 46 years old, people from Huizhou.Readme is often felt to have palpitation over nearest one month, is uncomfortable in chest, working Shi Jiachong, sleep are poor.Hyperlipidemia (consolidate by T-CHOL 5.65mmol/L, triglycerides 1.72mmol/L, low-density lipoprotein courage Alcohol 3.62mmol/L), homocysteine is higher (19.5 μm of ol/L).Through recommending to take feature guarantor of the present invention Strong product particle electuary, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with warm water, subjective symptoms is obvious after continuously taking one month Mitigate, and do not occur the symptoms such as gastrointestinal discomfort, stool is normal.
25th, Peng XX, man, 65 years old, people from Changsha City, Hunan Province, retired professor.Oneself feel most recently to occur now and then Nervous, uncomfortable in chest, rapid heart beat is slept phenomena such as poor, Hyperlipidemia of having a medical check-up (T-CHOL 5.65mmol/L, triglycerides 1.73mmol/L, LDL-C 3.65mmol/L) and homocysteine it is higher (21 μm of ol/L).Through friend Friend, which introduces, uses functional health product particle electuary of the present invention, respectively takes a bag (10g/ bags) sooner or later daily, continuously takes Blood test indices have different degrees of reduction after one month, and original symptom occurs and made moderate progress, and feel that the state of mind is preferable.
26th, Peng XX, man, 60 years old, people from Guangzhou, retired professor.Nervous, uncomfortable in chest, shortness of breath is often felt in readme, adds when working Weight, sleep is poor, stool scleroma.Through recommending to take functional health product particle electuary of the present invention, each one wrap sooner or later daily (10g/ bags), is taken after mixing with liquid with 50-60 DEG C of warm water, and subjective symptoms mitigates after continuously taking 2 courses for the treatment of, and poor phenomenon of sleeping substantially changes Kind, stool is normal.
27th, Liao XX, man, 56 years old, people from Dongguan City, Guangdong Province.Nervous, the uncomfortable in chest, heart is most recently often felt in readme Jump soon, aggravated when working, sleep is poor, there is history of hypertension.Hyperlipidemia (T-CHOL 5.76mmol/L, triglycerides 1.75mmol/L, LDL-C 3.65mmol/L), homocysteine is higher (21.5 μm of ol/L).Through Functional health product particle electuary of the present invention is taken in recommendation, each one wraps (10g/ bags) sooner or later daily, is taken after mixing with liquid with warm water, Subjective symptoms mitigates after continuously taking one month, and poor phenomenon of sleeping makes moderate progress, and stool is normal.
28th, old XX, man, 50 years old, hengyang, hunan province people from city.Nervous, uncomfortable in chest, shortness of breath is often felt in readme in this year, sleeps It is poor to sleep, stool scleroma.Through recommending to take functional health product particle electuary of the present invention, each one (10g/ is wrapped sooner or later daily Bag), it is taken after mixing with liquid with warm water, subjective symptoms mitigates after continuously taking one month, and does not occur the symptoms such as gastrointestinal discomfort, and stool is just Often, poor phenomenon of sleeping makes moderate progress.
29th, woods X, man, 56 years old, Hunan Loudi City secondary school teachers.Nervous, uncomfortable in chest, rapid heart beat is often felt in readme, works Shi Jiachong, sleep is poor, stool scleroma.Look into Hyperlipidemia (T-CHOL 5.56mmol/L, triglycerides 1.71mmol/L, it is low close Spend lipoprotein cholesterol 3.45mmol/L).Through recommending to take functional health product particle electuary of the present invention, sooner or later daily Each bag (10g/ bags), is taken after mixing with liquid with warm water, and subjective symptoms mitigates after continuously taking one month, and stool is normal.
30th, thank to XX, man, 52 years old, people from Guangzhou.Nervous, uncomfortable in chest, shortness of breath is often felt in readme, is aggravated when working, and sleeps Difference, stool scleroma.Have a blood test fat (T-CHOL 5.55mmol/L, triglycerides 1.73mmol/L, LDL-C 3.60mmol/L), homocysteine (21 μm of ol/L).Through recommending to take functional health product particle of the present invention Electuary, each one (10g/ bags) is wrapped sooner or later daily, be taken after mixing with liquid with warm water, subjective symptoms substantially mitigates after continuously taking 2 courses for the treatment of, greatly Just it is normal.

Claims (10)

1. a kind of have the health products for removing vivotoxin function, it is characterised in that includes the component of following masses part:Fruits and vegetables ferment It is plain 20-40 parts, resistant dextrin 18-36 parts, FOS 16-32 parts, red yeast rice 4-16 parts, konjaku flour 2.5-7.5 parts, appropriate Vitamin and natural flavouring.
2. health products according to claim 1, it is characterised in that:Vitamin includes vitamin C, vitamin B6, folic acid, dimension Raw plain B12
3. health products according to claim 2, it is characterised in that:Vitamin C 300- is added in health products described in per 60kg 500g, vitamin B61-1.5g, folic acid 250-500mg, vitamin B1220-60mg。
4. health products according to claim 1, it is characterised in that:Natural flavouring includes steviol glycoside, citric acid, natural Fruits and vegetables extract.
5. health products according to claim 4, it is characterised in that:Steviol glycoside 60- is added in health products described in per 60kg 120g, citric acid 150-450g, natural fruit and vegetables extract 15-45g.
6. health products according to claim 1, it is characterised in that:Natural fruit and vegetables extract includes Fragaia ananassa Duchesne extract, apple Juice concentrated extract, mango concentrated extract, orange juice concentrated extract.
7. according to the health products described in claim any one of 1-6, it is characterised in that include the component of following masses part:Fruits and vegetables Ferment 25-35 parts, resistant dextrin 22-32 parts, FOS 19-29 parts, red yeast rice 7-13 parts, konjaku flour 3.5-6.5 parts, dimension life Plain C 350-450g, vitamin B61.15-1.4g, folic acid 300-450mg, vitamin B1230-50mg, steviol glycoside 75- 105g, citric acid 200-400g, natural fruit and vegetables extract 20-40g.
8. health products according to claim 7, it is characterised in that include the component of following masses part:30 parts of pectase, 29 parts of resistant dextrin, 25 parts of FOS, 10 parts of red yeast rice, 5 parts of konjaku flour, vitamin C 400g, vitamin B61.32g, leaf Sour 360mg, vitamin B1239mg, steviol glycoside 90g, citric acid 300g, natural fruit and vegetables extract 30g.
9. health products according to claim 1, it is characterised in that:Dosage form includes tablet, capsule, granule or oral Liquid.
10. a kind of preparation method with the health products for removing vivotoxin function, it is characterised in that comprise the following steps:
Each component is weighed according to the proportioning described in claim any one of 1-9;
By citric acid, natural fruit and vegetables extract, steviol glycoside, folic acid, vitamin B6, vitamin B12, vitamin C and resistant dextrin It is mixed evenly, obtains just mixed material;
Red yeast rice, FOS, pectase, konjaku flour are well mixed, just mixed material is added, is well mixed;
Different formulations is made as needed, after the assay was approved, is packaged to be finished product.
CN201710675234.XA 2017-08-09 2017-08-09 It is a kind of that there are health products for removing vivotoxin function and preparation method thereof Pending CN107692196A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
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CN116406755A (en) * 2023-04-26 2023-07-11 厦门市养真保健食品有限公司 Solid beverage containing high-activity enzyme and preparation method thereof

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