CN107412261A - With clear sugared oral liquid for repairing metabolic function and preparation method thereof - Google Patents
With clear sugared oral liquid for repairing metabolic function and preparation method thereof Download PDFInfo
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Abstract
It is a kind of that there is the clear sugared oral liquid for repairing metabolic function, including the following raw material：The parts by weight of trivalent chromium 0.3 0.4, the parts by weight of calcium 120 235, the parts by weight of yeast zinc 5 15, the parts by weight of sodium 25, the parts by weight of potassium sulfate 15 20, the parts by weight of yeast selenium 0.1 0.2, the parts by weight of lithium 0.05 0.1, the parts by weight of manganese 0.5 1.0, the parts by weight of copper 0.02 0.05, the parts by weight of ferric sulfate 50 70, the parts by weight of epsom salt 110 140, the parts by weight of phosphorus 100 160, the parts by weight of chlorogenic acid 160 220, the parts by volume of magma light-coloured vinegar 7 12, the volcanic rock extraction parts by volume of stoste 7 12, the parts by weight of Charantin 130 210.The clear sugared oral liquid can strengthening spleen and nourishing stomach, maintain acid-base balance, recover pancreatic functions, impaired liver cell is passed through itself repair ability to recover normal in structure；On the other hand, the enzyme in liver cell needed for various reactions and enzyme system is supplied and is recovered, correct sugar, protein and fat metabolic disturbance, recover the normal function of liver cell.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of to have the clear sugared oral liquid and its system for repairing metabolic function
Preparation Method.
Background technology
Either developed country or developing country, the incidence of disease of diabetes are all increasing year by year.Due to survey group's
Age, investigation method, diagnostic criteria and race, habits and customs, nutritional condition are different, and various countries' diabetes prevalence has significance difference
It is different.The illness rate of insulin-dependent diabetes mellitus (IDDM) is 0.07 ‰~3.4 ‰ in countries in the world.In Japan, China and Gu
Bar, IDDM illness rate is low, respectively 0.07 ‰, 0.09 ‰ and 0.14 ‰.Sweden, Finland's illness rate is respectively 1.48 ‰,
1.90 ‰, Britain IDDM illness rate highest, it is 3.4 ‰.Non-Insulin Dependent Diabetes Mellitus (NIDDM) is in the U.S., Sweden, day
State's illness rates such as sheet, Chile, Argentina about 5%~7%, the state such as West Europe, Eastern Europe, the Soviet Union, Canada, Australia illness rate is about
For 2%~5%, the state such as India, Philippine illness rate is about 1%~4%, there is difference between not agnate, and city is higher than rural area.
Predicted according to WHO latest datas, be up to current 5 times to the year two thousand twenty diabetes mellitus in China people, Asia and African diabetes patient will
It is current 3 times, therefore it has been the hot job too impatient to wait of one, the whole world to prevent and treat diabetes.
Impotence is the mark that diabetes aggravate, and sexual desire still may be present during women with diabetes early stage, heat rank
Section vaginal lubrication degree is normal, but orgasm forfeiter is more common.There is drying in aggravation, vagina, and vaginitis etc. easily occurs,
Dyspareunia can be caused.
Diabetic male patient commonly sex dysfunction, impotence etc..Statistics, male diabetes patient's impotence
Incidence is up to 40%~60%.
It is contemplated that the growth of diabetic's number, it is meant that more people will perplex by this disease,
Mean that we sacrifice the economic growth that health is brought and swallowed by Disease Spectrum, the heart disease caused by diabetes, brain soldier
In, renal failure, blindness, the severe complication such as amputation.
Liver is that diabetes form the real cause of disease：Human body diseases and aging, come from the obstacle of organism metabolism, the obstacle source of metabolism
It is unbalance from human body mineral element level.Body produces many metabolism rubbish daily, is medically " oxide " or cries " certainly
By base ", so-called free radical refers to that those are not metabolized out external rubbish in time in vivo, and these materials are outer-shell electron tracks
On, there is the atom of unpaired electronics, they attack normal cell, capture the electronics of other cells, make the complete of membrane structure
Property is destroyed, and causes liver cell to be damaged, and exception just occurs in liver damage blood sugar for human body.The real metabolism of diabetes is not
In pancreas islet, insulin, and it is liver, liver is the center of glycometabolism.
In enteron aisle, the starch in food is digested glucose absorption, and into after human body, glucose is in liver and muscle
Two local glycogen biosynthesis.Glycogen is the storage form of glucose in vivo, and popular say is exactly after glucose is packed, compressing
Storage.Glycogen has two kinds in human body, intramuscular to be referred to as muscle glycogen, is referred to as hepatic glycogen in liver.Muscle glycogen be to provide for
Energy needed for muscular movement, and the purpose of hepatic glycogen only has one, that is, maintains glucostasis.Why blood glucose will be stablized, both
Can not it is too low can not be too highBecause meaning existing for blood glucose mainly energizes to brain, red blood cell and marrow.Blood glucose one is low,
The brain of people cannot obtain enough energy supplies, and people just occurs that dizziness is even gone into a coma, and here it is hypoglycemia.
Blood glucose is too high, and one side sugar can cause to waste from urine ejection, and the cell of another aspect whole body is at hypertonic ring
Under border, intracellular many reactions can not be all smoothed out, and cause the generation of many illnesss.Occur one of blood glucose common asks
Topic is exactly blood glucose rise, causes diabetes.Untill today, almost all of medical science treatise, doctor and nutritionist are saying II
The cause of disease of patients with type Ⅰ DM is in exception of pancreas islet, insulin or insulin receptor etc..
The cause of disease by IDDM is misleading for the dead disappearance of islet cells, and people just habitually think type II diabetes
The basic cause of disease is also abnormal in pancreas islet and insulin, and this saying is unscientific.First, it is especially latent early stage diabetes
Fu Qi, the insulin level of patient is higher, at least in normal level, i.e., so in normal level, just illustrates the function of pancreas islet
It is normal, it is impossible to which diabetes are imputed to pancreas islet and insulin.And it is also to the later stage of diabetes, horizontal decline of insulin
It should be understood that because diabetes cause the angiogenesis lesion of whole body, the blood vessel in pancreas islet is also influenced whether certainly, and then lead
Cause pancreas islet that further lesion occurs.Second, diabetic is at least three big metabolic disorders, i.e. protein metabolism, fatty generation
Thank and carbohydrate metabolism disturbance, it might even be possible to which it is a kind of metabolic disease of human body most serious to say diabetes.And in three big metabolic disorders
In, protein metabolism disorder is often first occurred that, protein metabolism disorder is not easy to be noticeable or paid attention to；Next to that fat metabolism
Disorderly or carbohydrate metabolism disturbance, because fat metabolism and glycometabolism need enzyme caused by protein metabolism, the deficiency of enzyme is fat
One of the main reason for metabolic disorder and carbohydrate metabolism disturbance, as it was previously stated, fat people, the people of high fat of blood are internal shortage eggs
The people of white matter, it is fat generation quickening, the people of fat utilization obstacle.
All it is often clinically further to occur metabolism obstacles of blood glucose on this basis to lead diabetogenic generation, that is,
Say that clinically often the disorders of lipid metabolism of high fat of blood etc prior to the appearance of hyperglycaemia, is metabolized so the three of diabetic are big
Disorder is not that the secretion of the still more early stage insulin of diabetes is often normal because caused by insulin secretion disorder
's.
3rd, the center that liver is only protein, fat and sugar three is metabolized greatly, it is big that the dysfunction of liver may result in this three
The disorder of metabolisable form.
From the regulation of the insulin of blood glucose it is also seen that liver dysfunction role in diabetes, when blood glucose liter
Height, pancreas islet can experience the more insulin of secretion, and insulin action tells them to hasten to reclaim blood in performing organ liver etc.
In unnecessary sugar, perform organ and take action together, blood glucose just lowers.It is different by sugar after the liver dysfunction of organ is performed
Raw glycogen synthesis ability will decline, and cause recovery ability of the liver to blood glucose to decline, and blood glucose rise.
Why it is liver rather than muscleBecause the execution organ of blood glucose-control is mainly liver rather than muscle, on the one hand,
Liver that is, the glucose packing in blood, can be stored in liver by gluconeogenesis glycogen biosynthesis after blood glucose rise.On the other hand,
Liver can also be transformed into unnecessary sugar fat and be stored up.
When people do not understand these details reasons, only will be considered that diabetes is exactly blood glucose rise, so just can be appreciated that
Clinically doctor only eats antidiabetic drug to diabetes patient or beats insulin to correct glycometabolism, and protein metabolism and fat metabolism are disorderly
Do not manage disorderly, even if so what diabetes patient said in strict accordance with doctor, honestly hypoglycemic, and finally it also occur that complication, just
It is because the only not result to caused by any measure is taken in three big metabolic disorders to hypoglycemic.
The content of the invention
An object of the present invention is overcome the deficiencies in the prior art and provides a kind of clear sugar for having and repairing metabolic function
Oral liquid, the oral liquid, by human liver, courage, spleen, pancreas, stomach and intestine and blood vessel, the histocyte such as activation liver and gall, repairing and living
Change liquid, make the mineral metal enzyme in liver cell needed for various reactions obtain abundance supply and body itself enzyme system repaiied
It is multiple, it can fundamentally cure diabetes.
The second object of the present invention is the preparation method for providing the above-mentioned clear sugared oral liquid for having and repairing metabolic function.
The technical scheme is that：
It is a kind of that there is the clear sugared oral liquid for repairing metabolic function, including the following raw material：
Trivalent chromium 0.3-0.4 parts by weight, calcium 120-235 parts by weight, yeast zinc 5-15 parts by weight, sodium 2-5 parts by weight, sulfuric acid
Potassium 15-20 parts by weight, yeast selenium 0.1-0.2 parts by weight, lithium 0.05-0.1 parts by weight, manganese 0.5-1.0 parts by weight, copper 0.02-
0.05 parts by weight, ferric sulfate 50-70 parts by weight, epsom salt 110-140 parts by weight, phosphorus 100-160 parts by weight, chlorogenic acid
160-220 parts by weight, magma light-coloured vinegar 7-12 parts by volume, volcanic rock extraction stoste 7-12 parts by volume, Charantin 130-210 weight
Part.
The unit of wherein described parts by weight and parts by volume is a gram corresponding liter, that is to say, that when parts by weight are gram, in formula
Parts by volume corresponds to rise, and parts by weight are milligram hour, and the parts by volume in formula corresponds to milliliter.
The present invention can also add astragalin 60-80 parts by weight in the clear sugared oral liquid with reparation metabolic function.
The present invention can also add panaxoside 60-80 parts by weight in the clear sugared oral liquid with reparation metabolic function.
The present invention can also add Semen euryales extract 65-70 parts by weight in the clear sugared oral liquid with reparation metabolic function.
The present invention can also add mulberry-leaf extract 30-50 parts by weight in the clear sugared oral liquid with reparation metabolic function.
The preferred 0.08-0.1 parts by weight of dosage of wherein described lithium.
The wherein described preferred bark of eucommia chlorogenic acid of chlorogenic acid, the preferred 180-200 parts by weight of dosage.
The preferred 160-210 parts by weight of dosage of wherein described Charantin.
The raw material of the trivalent chromium is yeast chromium.
The raw material of the calcium is calcium sulfate or calcium carbonate.
The raw material of the sodium is sodium sulphate or sodium chloride, preferably sodium chloride.
The raw material of the lithium is lithium carbonate.
The raw material of the manganese is manganese sulfate.
The raw material of the copper is copper sulphate or copper chloride.
The raw material of the phosphorus is ammonium phosphatide.
The preparation method of wherein described volcanic rock extraction stoste is as follows：
(1) volcanic crater rock is broken into pieces and added in reaction vessel, add the water of 5-7 times of volcanic crater rock weight, that is,
It is volcanic rock to say 1, and 5-7 is pure water, and pure water is 5-7 times of volcanic rock weight.
(2) 120-160 degree is then heated to, is reacted 15-30 minutes, cooling, 90-110 degree is then heated to and continues to react
3-4 hours, cool down centrifugal filtration later in 2 hours and take supernatant.
(3) filter residue is inserted in storage tank plus 1-2 times of water immersion, 2 hours filtering discarded objects of precipitation are outwelled, and crosses cleaner liquid and step
Suddenly the supernatant that (2) obtain mixes to obtain volcanic rock extraction stoste.
Containing mineral matters such as abundant sodium, magnesium, aluminium, silicon, calcium, manganese, iron, phosphorus, nickel, cobalt, molybdenums in the rock of volcanic crater.
The present invention has the preparation method for the clear sugared oral liquid for repairing metabolic function as follows：
(a) required raw material is weighed by formula；
(b) volcanic rock is extracted in stoste input pod, regulation pH value to 1.5-2 (is adjusted with hydrochloric acid, sulfuric acid or carbonic acid
Section), addition calcium, epsom salt, ferric sulfate, potassium sulfate, after mixing slowly 3-5 minutes, trivalent chromium is added, continue to stir 3-5
Minute；Magma light-coloured vinegar, yeast selenium are put into volcanic rock mixed liquor and stirred 5-8 minutes again；
(c) stirring 3-5 minutes in mixed liquor and then by yeast zinc, sodium are put into, then chlorogenic acid and Charantin are added into mixing
5-10 minutes are stirred in liquid, finally plus lithium, manganese, copper, phosphorus stir 15-20 minutes, obtain oral with the clear sugar for repairing metabolic function
Liquid.
With chlorogenic acid one in step (c) when needing to add astragalin, panaxoside, Semen euryales extract, mulberry-leaf extract
Rise and add.
0.02% plus flavoring product Stevioside and it can also be stirred 5-10 minutes in proportion in step (c).
The preparation method that the present invention has the clear sugared oral liquid for repairing metabolic function also comprises the following steps：
(d) quality inspection
Quality with the clear sugared oral liquid for repairing metabolic function is checked by following items：Visual examination (including it is clear
Lightness inspection), the inspection of device difference, health examination, Qualitive test, physical and chemical index, microorganism limitation etc..The inspection of these projects
Look into, the quality of oral liquid can be efficiently controlled, after the assay was approved sealing bottling.
The present invention have repair metabolic function clear sugared oral liquid can strengthening spleen and nourishing stomach, maintain acid-base balance, recover pancreas
Function, impaired liver cell is set to pass through itself repair ability to recover normal in structure；On the other hand, make various in liver cell
Enzyme and enzyme system needed for reaction are supplied and recovered, and are corrected sugar, protein and fat metabolic disturbance, are being recovered liver cell just
Chang Gongneng.
The present invention has the clear sugared oral liquid scope of application for repairing metabolic function：It is immune that power is low, resistance against diseases is poor, body
In weak more disease, poor appetite, eye-blurred, type 1 diabetes, diabetes B, high fat of blood, obesity, hypertension, hyperglycaemia, brains
The dysbolism crowds such as wind, cerebral thrombus plug, cardiovascular and cerebrovascular diseases, senile dementia, tumour, gout are in the scope of application.
The present invention has the clear sugared oral liquid action principle for repairing metabolic function as follows：
The real cause of disease of diabetes is liver not in pancreas islet and insulin, therefore liver is the center of glycometabolism, and liver is people
The center of body glycometabolism.
It is raw with traditional Chinese and western medicine, nutrition, naturopathy, Modern medical science, modern times first in clear sugared oral liquid of the invention
Object wave medical science dynamic acid-base balance principle, supplies the unbalance mineral element of body, protects liver cell from damage, protects cell membrane
The integrality of structure is not destroyed, and is corrected three big metabolic disorders of liver, impaired liver cell is passed through itself repair ability
And recover normal in structure rapidly；
Secondly, by human liver, courage, spleen, pancreas, stomach and intestine and blood vessel, the histocyte such as activation liver and gall, repairing activation
Liquid, make the mineral metal enzyme in liver cell needed for various reactions obtain abundance supply and body itself enzyme system repaired.
Thirdly, the mineral element in clear sugared oral liquid, there is good bioactivity, be easy to pass through human body blood-brain barrier,
Its biological effect (element therapy) is played into human body, the effect of " element therapy " is that element quickly enters the water-soluble of cell peripheral
Property microenvironment, the metabolic activity of cell is participated in, to toxic biological and chemical material, whether virus, germ, or again
Metal, agricultural chemicals, antibiotic, food additives etc., all by tissue, body fluid, cell and intraorganic element and biology
Balance, coordinate the effect with chemical combination to release its toxicity, make hepatic duct, the impurity on internal organs vascular wall and toxin separation, remove
The toxin of liver is accumulated in vivo, recovers liver toxin expelling metabolic function, and mineral element balance is fundamentally to cure diabetes
Definitely ensure.
The present invention has the clear sugared oral liquid action step for repairing metabolic function as follows：
The first step, research show that zinc is present in human body in each body fluid, tissue, cell and organ, 6% in human body
Zn-ef ficiency is present in skin, and in epidermis and corium, the content in its mesocuticle wants high 5 times.Zinc is the requirement for being only second to iron
Larger trace element, it is the constituent of more than 200 kinds of zinc enzyme, is the activator of enzyme, the zinc fat egg using zinc as Major Members
Played a significant role in vain in nucleic acid metabolism and protein synthesis.
Second step, the obstacle of organism metabolism come from caused rubbish daily, are medically " oxide " or cry " freely
Base ", so-called free radical refer to that those are not metabolized out external rubbish in time in vivo, and these materials are on outer-shell electron track,
Have the atom of unpaired electronics, they attack normal cells, capture the electronics of other cells, make the integrality of membrane structure by
To destruction, liver cell is caused to be damaged, and exception just occurs in liver damage blood sugar for human body.
Fat metabolism and glycometabolism need to rely on enzyme caused by protein metabolism, and the deficiency of enzyme is fat metabolic disturbance and sugar
One of the main reason for metabolic disorder, fat people, the people of high fat of blood are the internal people for lacking protein, are that fat generation adds
It hurry up, the people of fat utilization obstacle.
Selenium, manganese are one of mineral element metalloenzyme Major Members, and they participate in many enzymic catalytic reactions, promote the egg of human body
White matter generates, and bone grows, and about limits fatty formation speed, protects complete, the normal sugar of maintenance of particulate body in cell
Metabolism and fat metabolism.
Selenium, manganese cause the disorderly cellular level of glycometabolism by stablizing liver, protect the integrality of membrane structure by
To destruction, protection liver cell is damaged and influences glycometabolism, lifts body immunity, and antioxidation is electric with free radical in time
Son is peering, releases its aggressiveness, decomposes and remove free radical, it is smoothly metabolized out in vitro, in mineral element oral liquid sugared clearly
Play chief commander.
Elemental lithium in 3rd step, clear sugared oral liquid, lithium have the effect of statocyte blood sugar level, directly stimulate and cause sugar
The disorderly effect of metabolism, therefore blood glucose is both reduced, it can also make blood glucose rise, lithium effect is amphicheirality.
Elemental lithium effect is the direct disorderly cellular level for stimulating liver to cause glycometabolism, reduces blood glucose.Work as blood glucose
Rise, pancreas islet can experience the more insulin of secretion, and insulin action makes it perform organ liver, returned in performing organ, liver etc.
Sugar unnecessary in blood is received, blood glucose just lowers.After the liver dysfunction of organ is performed, pass through the Glycogen synthesis of gluconeogenesis
Ability will decline, and cause recovery ability of the liver to blood glucose to decline, and blood glucose rise, and master is played in mineral element oral liquid sugared clearly
Lead effect.
4th step, molybdenum, magnesium are the essential enzyme members of a kind of participation organism normal activities and metabolic processes
Plain component, played an important role in organization of human body and function, and more than the reaction of 300 kinds of biochemical enzymes in participant's body.Adult
Human body has about 25 grams of magnesium, and 60%~65% magnesium is present in bone, and 27% in muscle, and 6-7% is in other cells, carefully
The magnesium of extracellular fluid is no more than 1%.
Magnesium influences a variety of biological functions of cell：The transhipment of potassium ion and calcium ion is influenceed, the transmission of adjustment signal, is participated in
The synthesis of energetic supersession, protein and nucleic acid；Can be by being complexed negative electrical charge group, the especially phosphate group in nucleotides is sent out
Wave the 26S Proteasome Structure and Function for maintaining material；The activation and suppression of catalyzing enzyme and the tune of cell cycle, cell propagation and cell differentiation
Control, participate in maintaining the stability of genome.Play during nervimuscular function normal operation, blood glucose conversion etc. important
Role.In the metabolism of calcium, vitamin C, phosphorus, sodium, potassium etc., magnesium is necessary material.
5th step, cobalt, iron are the most trace elements of human body requirement, and cobalt is one necessary group of vitamin B12 molecule
Point, B12 is to form composition necessary to hemoglobin.One adult, about 3~5 grams of whole body iron-holder, wherein except 70~
80% is in the form of hemoglobin, is present in red blood cell China and foreign countries, about 10% is distributed in muscle and other cells, is flesh red eggs
One of constituent of bletilla iron enzyme.Some is referred to as storeing iron, stores in liver, spleen, marrow, intestines and placenta
In, account for the 15~20% of total amount.In addition, also a small amount of iron, in the form of being combined with protein, is present in blood plasma,
Referred to as blood plasma iron, quantity are about 3 milligrams.Hemoglobin can deliver to oxygen body tissue, and iron is the important composition of hemoglobin
Part, liver are the pillars of glycometabolism, if body burden's iron level reduces, the hemoglobin synthesis of liver will be by shadow
Ring, dysbolism will occur, cobalt, iron are the important compositions of mineral element oral liquid sugared clearly.
6th step, sodium and potassium are the main electrolytes in body fluid, and important regulation is played to body body fluid equiblibrium mass distribution and is made
With, they must be balanced against others, and control the water balance of human body in normal human jointly, and sodium ion accounts for extracellular fluid sun
The 92% of total ion concentration, potassium ion account for 98% or so of intracellular fluid cation total amount；Sodium, the relative equilibrium of potassium ion, maintain
The complete of the function and structure of whole cell, potassium can excrete the sodium of internal surplus.
Calcium is the source of human life evolution, is to form the most element of human body.Function of the calcium ion to cardiac muscle cell,
When extracellular Ca2+ concentration raises within the specific limits, cause myocardial contraction to speed, palpitate quickly, be i.e. increased heart rate；When
When extracellular Ca2+ concentration is higher, cause calcium ion to be continuously increased with troponin combined amount, even up to only combine and do not understand
From degree, then, heart can stop at contraction state, and it is stiff that calcium occurs in cardiac muscle.During human body calcium deficiency, pth secretion is stimulated
Parathormone, so that blood calcium raises；Long-term blood calcium increases, and it is hypertrophy arthrosis to form spur etc. in the crucial portion in joint
Lesion, so spur, osteoproliferation are the secondary arthritis of human body calcium deficiency, coordination is played in mineral element oral liquid sugared clearly and is made
With.
7th step, copper, phosphorus are one of particularly important elements of body, and it is ribonucleic acid, deoxidation core in all cells
One of constitution element of ribosomal ribonucleic acid, it is the indispensable element of all cells of organism, is to maintain the integrality of cell membrane, play cell
Necessary to function, it can help the synthesis of cell division, propagation and albumen, stimulate neuromuscular, heart and muscle is had rule
Shrink on rule ground.Phosphorus is the important component of human genetic material nucleic acid, and the key substance atriphos of human energy's conversion
(ATP) important component, and a kind of unique and extremely effective catalyst in biosystem, be more than 30 kinds of enzyme activity into
Point, the component of biological film phospholipid, it promotes the decomposition of fat and aliphatic acid, prevents to assemble too many acid or alkali, the work(of phosphorus in blood
Can also influence the acid-base balance in blood plasma and cell, promote material absorbing, stimulate the secretion of hormone, help glucose, protein,
The metabolism of fat.It is to form bone, the important component of tooth, important adjustment effect is played to human metabolism, to biology
The heredity of body be metabolized, grown, energy supply etc. is all indispensable, and participation enzymatic is anti-in clear sugared oral liquid
Process is answered, is helped out.
8th step, trivalent chromium influence the metabolism of carbohydrate, lipid, protein and nucleic acid etc., influence the growth of animal, breeding,
Resistance against diseases, the biological chemistry action of chromium influence sugar, protein, fat primarily as the reinforcing agent of insulin by insulin
The metabolism of fat and nucleic acid, it is GTF in brewer's yeast (Glucose Tolerance Factor, GTF) activity
Part.Chromium is the confactor that insulin plays a role, and is played an important role in glycometabolism, is supplemented to diabetic
Appropriate chromium, it is the sugar tolerance factor, increases the utilization of glucose, accelerate the oxidation of butanedioic acid.Chromium can increase cholesterol decomposition and
Excretion, can not only reduce the deposition of cholesterol on sustainer, and can remove and be deposited on Supraaortic cholesterol, strengthen fat egg
The activity of white enzyme and lecithin cholesterol acyltransferase, so as to enhance the synthesis of HDL.On the one hand animal is worked as
When body lacks chromium, the biological activity of insulin reduces, impaired glucose tolerance, and glycometabolism triggers disorders of lipid metabolism, so chromium is
One of clear sugared oral liquid Main Ingredients and Appearance.
It is with natural volcanic crater rock extract solution that the present invention, which has the clear sugared oral liquid of reparation metabolic function, is aided with natural plant
Thing monomer constituents and trace element, after measured without any toxicity, liver, kidney and other organs are not produced with the secondary influence of any poison.
The present invention has the clear sugared oral liquid instructions of taking for repairing metabolic function：Three times a day, each 20ml (one bottle), temperature
Water is taken, and 30 days are 1 course for the treatment of.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.
In following examples, the raw material of the trivalent chromium is yeast chromium；The raw material of the calcium is calcium carbonate；The original of the sodium
Expect for sodium chloride；The raw material of the lithium is lithium carbonate；The raw material of the manganese is manganese sulfate；The raw material of the copper is copper sulphate；Institute
The raw material for stating phosphorus is ammonium phosphatide, and chlorogenic acid is bark of eucommia chlorogenic acid, and magma light-coloured vinegar meets standard GB/T 18187-2000, with acetic acid
Meter, total acid content 4.5g/100mL.
The purity of the chlorogenic acid is 95%, and the purity of the Charantin is 90%, astragalin and panaxoside
Purity is 80%, and Semen euryales extract is water extraction extract, and every 30 kilograms of raw materials extract 1 kilogram of Semen euryales extract, mulberry leaf extraction
Thing is water extraction extract, and every 30 kilograms of raw materials extract 1 kilogram of mulberry-leaf extract,
The preparation method of wherein described volcanic rock extraction stoste is as follows：
(1) volcanic crater rock is broken into pieces and added in reaction vessel, add the water of 5 times of volcanic crater rock weight, that is to say, that 1
It is pure water for volcanic rock, 5, pure water is 5 times of volcanic rock weight.
(2) 150 degree are then heated to, is reacted 20 minutes, cooling, 100 degree is then heated to and continues reaction 3 hours, cooling 2
Centrifugal filtration takes supernatant after hour.
(3) filter residue is inserted in storage tank plus 1.5 times of water immersions, 2 hours filtering discarded objects of precipitation are outwelled, and crosses cleaner liquid and step
Suddenly the supernatant that (2) obtain mixes to obtain volcanic rock extraction stoste.
Volcanic crater rock is the great Lian ponds volcanic crater rock of Heilongjiang Province five.
Embodiment 1
Trivalent chromium 330ug calcium 220.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 150mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml volcanic rocks extraction stoste 10ml Charantins 207mg
Common 20ml
Embodiment 2
Trivalent chromium 330ug calcium 120.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml volcanic rocks extraction stoste 10ml Charantin 207mg astragalins 70mg
Embodiment 3
Trivalent chromium 330ug calcium 120.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml volcanic rocks extraction stoste 10ml Charantin 207mg astragalin 70mg panaxosides 70mg
Common 20ml
Embodiment 4
Trivalent chromium 330ug calcium 150.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml volcanic rocks extract stoste 10ml Charantin 137mg Semen euryales extract 70mg astragalin 70mg mulberry-leaf extracts
40mg
Common 20ml
Embodiment 5
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 120mg phosphorus 120mg chlorogenic acid 180mg magma
Light-coloured vinegar 9ml volcanic rocks extraction stoste 10ml Charantin 177mg Semen euryales extract 70mg astragalins 70mg
Common 20ml
Embodiment 6
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml volcanic rocks extraction stoste 10ml Charantin 137mg Semen euryales extract 70mg astragalins 70mg
Embodiment 7
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml volcanic rocks extraction stoste 10ml Charantin 137mg mulberry-leaf extract 40mg astragalins 70mg
Embodiment 8
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 9ml rocks extraction stoste 10ml Charantin 137mg Semen euryales extract 70mg astragalin 70mg mulberry-leaf extracts 40mg
Embodiment 9
Trivalent chromium 325ug calcium 160mg yeast zinc 12mg sodium 3mg potassium sulfate 18.5mg yeast selenium 163ug lithiums 84ug
Manganese 850ug copper 38ug ferric sulfate 64mg epsom salt 127mg phosphorus 135mg chlorogenic acid 195mg magma light-coloured vinegars 10ml fire
Mountain rock extraction stoste 9ml Charantin 170mg Semen euryales extract 70mg astragalin 74mg mulberry-leaf extracts 43mg
Embodiment 10
Trivalent chromium 325ug calcium 160mg yeast zinc 12mg sodium 3mg potassium sulfate 18.5mg yeast selenium 163ug lithiums 84ug
Manganese 850ug copper 38ug ferric sulfate 64mg epsom salt 127mg phosphorus 125mg chlorogenic acid 195mg magma light-coloured vinegars 8ml fire
Mountain rock extraction stoste 11ml Charantin 170mg Semen euryales extract 72mg astragalin 73mg mulberry-leaf extracts 42mg
Comparative example 1
Comparative example 1 removes chlorogenic acid on the basis of embodiment 8, and other are same as Example 8, and specific formula is as follows：
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg magma light-coloured vinegar 9ml volcanoes
Rock extraction stoste 10ml Charantin 137mg Semen euryales extract 70mg astragalin 70mg mulberry-leaf extracts 40mg
Comparative example 2
Comparative example 2 removes magma light-coloured vinegar on the basis of embodiment 8, and rock extraction stoste is changed to 19ml, other and implementation
Example 8 is identical, and specific formula is as follows：
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg volcanoes
Rock extraction stoste 19ml Charantin 137mg Semen euryales extract 70mg astragalin 70mg mulberry-leaf extracts 40mg
Comparative example 3
Comparative example 2 removes rock extraction stoste on the basis of embodiment 8, and magma light-coloured vinegar is changed to 19ml, other and implementation
Example 8 is identical, and specific formula is as follows：
Trivalent chromium 330ug calcium 170.231mg yeast zinc 10mg sodium 2.3mg potassium sulfate 17.682mg yeast seleniums 161ug
Lithium 80ug manganese 847ug copper 39ug ferric sulfate 61.33mg epsom salt 130mg phosphorus 110mg chlorogenic acid 200mg magma
Light-coloured vinegar 19ml Charantin 137mg Semen euryales extract 70mg astragalin 70mg mulberry-leaf extracts 40mg
Above example, the preparation method of comparative example are as follows：
(a) required raw material is weighed by formula；
(b) volcanic rock is extracted in stoste input pod, regulation pH value to 1.5, addition calcium, epsom salt, sulfuric acid
Iron, potassium sulfate, after mixing slowly 5 minutes, trivalent chromium is added, continues stirring 5 minutes；Put magma light-coloured vinegar, yeast selenium into fire again
In the rock mixed liquor of mountain and stir 5 minutes；
(c) and then yeast zinc, sodium are put into mixed liquor and stirred 5 minutes, then chlorogenic acid and Charantin are added into mixed liquor
Middle stirring 10 minutes, finally plus lithium, manganese, copper, phosphorus stir 15 minutes, and 0.02% adds flavoring product Stevioside and stirs 5-10 in proportion
Minute, obtain with the clear sugared oral liquid for repairing metabolic function.
With chlorogenic acid one in step (c) when needing to add astragalin, panaxoside, Semen euryales extract, mulberry-leaf extract
Rise and add.
(d) quality inspection
Checked by following items：Visual examination (including clarity test), the inspection of device difference, health examination,
Qualitive test, physical and chemical index, microorganism limitation etc., sealing bottling after the assay was approved, per bottled 20ml, packing specification 20ml × 10
Bottle × 40 boxes.
The using effect of above example and comparative example is as follows：
(1) hyperglycemia patient using effect:
Fasting blood-glucose is more than 6, and postprandial blood sugar is more than or equal to 7.7 can say it is hyperglycaemia, will be not reaching to diabetes mark
The accurate people of hyperglycemia patient 260, is equally divided into 13 groups, every group of 20 people, takes having for embodiment 1-10 and comparative example 1-3 respectively
The clear sugared oral liquid of metabolic function is repaired, three times a day, each 20ml (one bottle), warm water is taken, and 30 days are 1 course for the treatment of, take 5
The individual course for the treatment of, diet low suger diet, after 5 courses for the treatment of, embodiment 1-10 Fasting Glucose and postprandial blood sugar full recovery are normal,
Comparative example 1 only has 3 to recover normal, and comparative example 2 only has 4 to recover normal, and comparative example 3 only has 3 to recover normal.
(2) type 1 diabetes people using effect:
Type 1 diabetes people 130,13 groups are equally divided into, every group of 10 people, takes embodiment 1-10 and comparative example 1-3 respectively
Have repair metabolic function clear sugared oral liquid, 3 times a day, each 20ml (one bottle), warm water is taken.These patients blood before the meal
The average 14mmol/L of sugar, the average 21mmol/L of postprandial blood sugar, main suit's giddy, tinnitus, uncomfortable in chest, shortness of breath, insomnia, takes three times a day
Antidiabetic drug diformin tablet maintains.The effect for taking clear sugared oral liquid is shown in Table 1：
Table 1
(2) diabetes B people using effect:
Diabetes B people obese patient 130 (than my standard weight obesity 20-30%), is equally divided into 13 groups, every group
10 people, that takes embodiment 1-10 and comparative example 1-3 respectively has the clear sugared oral liquid for repairing metabolic function, 3 times a day, every time
20ml (one bottle), warm water is taken.These patients average blood sugar 15mmol/L, postprandial average blood sugar 21mmol/L, daily three before the meal
Secondary insulin injection, main suit's giddy, tinnitus, uncomfortable in chest, shortness of breath, insomnia, antidiabetic drug maintenance is taken three times a day.It is oral to take clear sugar
The effect of liquid is shown in Table 2：
Table 2
Diabetes B patient 90% is in obese state, and experiment proves, diabetes B patient takes the clear sugared mouth of the present invention
Taking liquid has loss of weight effect, and weight loss effect is shown in Table 3 after taking 10 courses for the treatment of：
Table 3
Claims (10)
1. a kind of have the clear sugared oral liquid for repairing metabolic function, it is characterised in that including the following raw material：Trivalent chromium 0.3-0.4 weights
Measure part, calcium 120-235 parts by weight, yeast zinc 5-15 parts by weight, sodium 2-5 parts by weight, potassium sulfate 15-20 parts by weight, yeast selenium
0.1-0.2 parts by weight, lithium 0.05-0.1 parts by weight, manganese 0.5-1.0 parts by weight, copper 0.02-0.05 parts by weight, ferric sulfate 50-70
Parts by weight, epsom salt 110-140 parts by weight, phosphorus 100-160 parts by weight, chlorogenic acid 160-220 parts by weight, magma light-coloured vinegar 7-
12 parts by volume, volcanic rock extraction stoste 7-12 parts by volume, Charantin 130-210 parts by weight；Wherein described parts by weight and volume
The unit of part is a gram corresponding liter.
2. there is the clear sugared oral liquid for repairing metabolic function according to claim 1, it is characterised in that the Radix Astragali can also be added
Glucoside 60-80 parts by weight.
3. there is the clear sugared oral liquid for repairing metabolic function according to claim 2, it is characterised in that ginseng can also be added
Saponin 60-80 parts by weight.
4. there is the clear sugared oral liquid for repairing metabolic function according to claim 2, it is characterised in that Gorgon fruit can also be added
Extract 65-70 parts by weight.
5. there is the clear sugared oral liquid for repairing metabolic function according to claim 2 or 4, it is characterised in that mulberry can also be added
Leaf extract 30-50 parts by weight.
6. there is the clear sugared oral liquid for repairing metabolic function according to claim 1, it is characterised in that the dosage of the lithium is
0.08-0.1 parts by weight.
7. there is the clear sugared oral liquid for repairing metabolic function according to claim 1, it is characterised in that the use of the chlorogenic acid
Measure as 180-200 parts by weight.
8. having the clear sugared oral liquid for repairing metabolic function according to claim 1, the raw material of the trivalent chromium is yeast chromium；
The raw material of the calcium is calcium sulfate or calcium carbonate；The raw material of the sodium is sodium sulphate or sodium chloride；The raw material of the lithium is
Lithium carbonate；The raw material of the manganese is manganese sulfate；The raw material of the copper is copper sulphate or copper chloride；The raw material of the phosphorus is ammonium phosphorus
Fat.
9. there is the clear sugared oral liquid for repairing metabolic function according to claim 1, it is characterised in that the volcanic rock extraction
Take the preparation method of stoste as follows：
(1) volcanic crater rock is broken into pieces and added in reaction vessel, add the water of 5-7 times of volcanic crater rock weight；
(2) then heat to 120-160 degree, react 15-30 minutes, cooling, then heat to 90-110 degree and continue to react 3-4 small
When, cool down centrifugal filtration later in 2 hours and take supernatant；
(3) filter residue is inserted in storage tank plus 1-2 times of water immersion, 2 hours filtering discarded objects of precipitation are outwelled, and crosses cleaner liquid and step
(2) supernatant obtained mixes to obtain volcanic rock extraction stoste.
10. there is the preparation method for the clear sugared oral liquid for repairing metabolic function according to claim 1, it is characterised in that successively
Comprise the following steps：
(a) required raw material is weighed by formula；
(b) will volcanic rock extract stoste input pod in, regulation pH value arrive 1.5-2, add calcium, epsom salt, ferric sulfate,
Potassium sulfate, after mixing slowly 3-5 minutes, trivalent chromium is added, continue to stir 3-5 minutes；Put magma light-coloured vinegar, yeast selenium into fire again
In the rock mixed liquor of mountain and stir 5-8 minutes；
(c) stirring 3-5 minutes in mixed liquor and then by yeast zinc, sodium are put into, then chlorogenic acid and Charantin are added in mixed liquor
5-10 minutes are stirred, finally plus lithium, manganese, copper, phosphorus stir 15-20 minutes, obtain with the clear sugared oral liquid for repairing metabolic function.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107951027A (en) * | 2018-01-15 | 2018-04-24 | 中鸿纳米纤维技术丹阳有限公司 | A kind of pelelith composite nutrient for strengthening anti-cancer tumor suppressor function |
| CN108310287A (en) * | 2018-04-26 | 2018-07-24 | 深圳安济堂医药科技有限公司 | Oral solution for the treatment of cancer and preparation method thereof |
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| CN1325636A (en) * | 2000-05-26 | 2001-12-12 | 孙天民 | Hypoglycemic corn food and its preparing process |
| CN101940620A (en) * | 2010-09-14 | 2011-01-12 | 广州市和藤医药研究开发有限公司 | Medicinal composition for treating diabetes mellitus and application thereof |
| CN106853158A (en) * | 2015-12-09 | 2017-06-16 | 陆艺文 | A kind of nutrient formulation of auxiliary treatment type ii diabetes and the method for aiding in the absorption of its component |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1325636A (en) * | 2000-05-26 | 2001-12-12 | 孙天民 | Hypoglycemic corn food and its preparing process |
| CN101940620A (en) * | 2010-09-14 | 2011-01-12 | 广州市和藤医药研究开发有限公司 | Medicinal composition for treating diabetes mellitus and application thereof |
| CN106853158A (en) * | 2015-12-09 | 2017-06-16 | 陆艺文 | A kind of nutrient formulation of auxiliary treatment type ii diabetes and the method for aiding in the absorption of its component |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107951027A (en) * | 2018-01-15 | 2018-04-24 | 中鸿纳米纤维技术丹阳有限公司 | A kind of pelelith composite nutrient for strengthening anti-cancer tumor suppressor function |
| CN108310287A (en) * | 2018-04-26 | 2018-07-24 | 深圳安济堂医药科技有限公司 | Oral solution for the treatment of cancer and preparation method thereof |
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