CN107334963A - A kind of medicament for treating nephrotic syndrome and preparation method thereof - Google Patents
A kind of medicament for treating nephrotic syndrome and preparation method thereof Download PDFInfo
- Publication number
- CN107334963A CN107334963A CN201710434387.5A CN201710434387A CN107334963A CN 107334963 A CN107334963 A CN 107334963A CN 201710434387 A CN201710434387 A CN 201710434387A CN 107334963 A CN107334963 A CN 107334963A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicament
- nephrotic syndrome
- chinese
- root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 51
- 206010029164 Nephrotic syndrome Diseases 0.000 title claims abstract description 40
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 28
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 28
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 28
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 28
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 25
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 24
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 24
- 241001465251 Ephedra sinica Species 0.000 claims abstract description 24
- 241000112528 Ligusticum striatum Species 0.000 claims abstract description 24
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 24
- 241000405414 Rehmannia Species 0.000 claims abstract description 24
- 229910052602 gypsum Inorganic materials 0.000 claims abstract description 24
- 239000010440 gypsum Substances 0.000 claims abstract description 24
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 23
- 239000009636 Huang Qi Substances 0.000 claims abstract description 23
- 241000830535 Ligustrum lucidum Species 0.000 claims abstract description 23
- 240000001341 Reynoutria japonica Species 0.000 claims abstract description 23
- 235000018167 Reynoutria japonica Nutrition 0.000 claims abstract description 23
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 23
- 241001530038 Pantherophis obsoletus Species 0.000 claims abstract description 22
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 claims abstract description 20
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 claims abstract description 20
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 20
- 239000000203 mixture Substances 0.000 claims abstract description 10
- 239000003390 Chinese drug Substances 0.000 claims abstract description 7
- 241000736199 Paeonia Species 0.000 claims description 24
- 241000207925 Leonurus Species 0.000 claims description 19
- 241000245665 Taraxacum Species 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000000470 constituent Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
- 240000002853 Nelumbo nucifera Species 0.000 claims description 4
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 4
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 4
- 230000008901 benefit Effects 0.000 claims description 4
- 244000025254 Cannabis sativa Species 0.000 claims description 3
- 241000270295 Serpentes Species 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- MUKYLHIZBOASDM-UHFFFAOYSA-N 2-[carbamimidoyl(methyl)amino]acetic acid 2,3,4,5,6-pentahydroxyhexanoic acid Chemical compound NC(=N)N(C)CC(O)=O.OCC(O)C(O)C(O)C(O)C(O)=O MUKYLHIZBOASDM-UHFFFAOYSA-N 0.000 claims description 2
- 241001533104 Tribulus terrestris Species 0.000 claims description 2
- 238000009835 boiling Methods 0.000 claims description 2
- 239000003651 drinking water Substances 0.000 claims description 2
- 235000020188 drinking water Nutrition 0.000 claims description 2
- 239000008280 blood Substances 0.000 abstract description 24
- 210000004369 blood Anatomy 0.000 abstract description 22
- 230000000694 effects Effects 0.000 abstract description 22
- 241000411851 herbal medicine Species 0.000 abstract description 6
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 4
- 230000035622 drinking Effects 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 4
- 240000001949 Taraxacum officinale Species 0.000 abstract description 2
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 230000000857 drug effect Effects 0.000 abstract description 2
- 238000003786 synthesis reaction Methods 0.000 abstract description 2
- 230000001225 therapeutic effect Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 244000192528 Chrysanthemum parthenium Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 230000001151 other effect Effects 0.000 description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 201000010099 disease Diseases 0.000 description 8
- 210000004185 liver Anatomy 0.000 description 8
- 206010030113 Oedema Diseases 0.000 description 7
- 210000003734 kidney Anatomy 0.000 description 7
- 201000001474 proteinuria Diseases 0.000 description 7
- 210000002700 urine Anatomy 0.000 description 6
- 206010001580 Albuminuria Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 239000005556 hormone Substances 0.000 description 4
- 229940088597 hormone Drugs 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 230000004224 protection Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 208000031226 Hyperlipidaemia Diseases 0.000 description 3
- 230000035900 sweating Effects 0.000 description 3
- 240000006122 Chenopodium album Species 0.000 description 2
- 235000009344 Chenopodium album Nutrition 0.000 description 2
- 208000003623 Hypoalbuminemia Diseases 0.000 description 2
- 240000007171 Imperata cylindrica Species 0.000 description 2
- 244000059675 Lindernia crustacea Species 0.000 description 2
- 241000013557 Plantaginaceae Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 208000020832 chronic kidney disease Diseases 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 208000009928 nephrosis Diseases 0.000 description 2
- 231100001027 nephrosis Toxicity 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000008085 renal dysfunction Effects 0.000 description 2
- 230000005070 ripening Effects 0.000 description 2
- 239000004575 stone Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 208000009304 Acute Kidney Injury Diseases 0.000 description 1
- 241000169680 Aphloia theiformis Species 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- 206010060737 Congenital nephrotic syndrome Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 241000142975 Cornaceae Species 0.000 description 1
- 241000125183 Crithmum maritimum Species 0.000 description 1
- 241000380450 Danaus melanippus Species 0.000 description 1
- 241000234272 Dioscoreaceae Species 0.000 description 1
- 241000723281 Ephedra equisetina Species 0.000 description 1
- 241000218670 Ephedraceae Species 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000034767 Hypoproteinaemia Diseases 0.000 description 1
- 235000003332 Ilex aquifolium Nutrition 0.000 description 1
- 235000002296 Ilex sandwicensis Nutrition 0.000 description 1
- 235000002294 Ilex volkensiana Nutrition 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 240000007890 Leonurus cardiaca Species 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 206010030124 Oedema peripheral Diseases 0.000 description 1
- 241000207834 Oleaceae Species 0.000 description 1
- 206010031264 Osteonecrosis Diseases 0.000 description 1
- 241001529246 Platymiscium Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010037597 Pyelonephritis acute Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 208000033626 Renal failure acute Diseases 0.000 description 1
- 208000027032 Renal vascular disease Diseases 0.000 description 1
- 206010038548 Renal vein thrombosis Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 102000007562 Serum Albumin Human genes 0.000 description 1
- 108010071390 Serum Albumin Proteins 0.000 description 1
- 241000033695 Sige Species 0.000 description 1
- 206010041277 Sodium retention Diseases 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 1
- 244000044283 Toxicodendron succedaneum Species 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 201000011040 acute kidney failure Diseases 0.000 description 1
- 201000001555 acute pyelonephritis Diseases 0.000 description 1
- 208000012998 acute renal failure Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 210000003056 antler Anatomy 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 208000010643 digestive system disease Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 241001233957 eudicotyledons Species 0.000 description 1
- 201000004954 familial nephrotic syndrome Diseases 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 208000018685 gastrointestinal system disease Diseases 0.000 description 1
- 210000000585 glomerular basement membrane Anatomy 0.000 description 1
- 231100000853 glomerular lesion Toxicity 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000003119 painkilling effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 206010034674 peritonitis Diseases 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 208000015670 renal artery disease Diseases 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 201000005060 thrombophlebitis Diseases 0.000 description 1
- 208000000143 urethritis Diseases 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of medicament for treating nephrotic syndrome and preparation method thereof, belong to field of Chinese herbal medicine technology.The medicament of the present invention includes the medicinal herb componentses of following green natural：Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root, Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali.The present invention passes through the Chinese herbal medicine by certain proportioning from green natural, using decoction vessel decocting Traditional Chinese drug mixture, a kind of medicament for the effect for adjusting body, removing blood stasis and relieving pain, nourishing Yin and clearing heat, benefiting qi and nourishing blood and detumescence anti-inflammatory to reach treatment nephrotic syndrome by Inner of synthesis.The present invention grinds Chinese medicinal herbs to be decocted using marmite, is not only convenient for drinking, it is easier to absorption of human body, improves drug effect；Suitable therapeutic nephrotic syndrome of the present invention, curative for effect, effect significantly, safe ready and have no toxic side effect.
Description
Technical field
The invention belongs to field of Chinese herbal medicine technology, is related to Chinese medicine preparation, and in particular to a kind of medicine for treating nephrotic syndrome
Agent and preparation method thereof.
Background technology
Nephrotic syndrome abbreviation kidney is comprehensive, refers to as caused by Different types of etiopathogenises, is increased with glomerular basement membrane permeability small with kidney
One group of syndrome clinic based on the Glomerular lesions such as ball filtration rate reduction has four characteristicses：1. High-grade Proteinuria exceedes
3.5g/d, there can be lipid urine；2. hypoalbuminemia seralbumin is less than 30g/L；3. hyperlipidemia；4. oedema is according to difference
The cause of disease and pathology are divided into 3 classes by intrinsic：That is primary nephrotic syndrome congenital nephrotic syndrome, Secondary cases nephrotic syndrome.
Typical performance is High-grade Proteinuria (daily ＞ 3.5g/1.73m2 body surface areas), hypoalbuminemia (plasma albumin ＜ 30g/
L), whether oedema with hyperlipidemia diagnostic criteria should be High-grade Proteinuria and Hypoproteinemia.High-grade Proteinuria is glomerulus
The feature of disease, it is more rare to occur so substantial amounts of albuminuria in renal vascular diseases or renal tubular interstitium disease.Due to low
Proteinemia, hyperlipidemia and oedema are all the consequences of High-grade Proteinuria, it is therefore contemplated that the standard of diagnosis should be with High-grade Proteinuria
Based on.
Nephrotic syndrome is not a kind of title of disease, but represents one group of symptom, is various chronic kidney diseases behind.
The main complication Patients With Nephrotic Symdrome resistance of nephrotic syndrome declines, and easily infects, common are respiratory tract infection
With urethral infection, primary peritonitis, cellulitis.Because blood is in hypercoagulative state, renal vein thrombosis, lung bolt easily occurs
The thrombophlebitis etc. of plug, PeV.The shortage of vitamin D and zinc can also be caused, it is easy to cause that human body is weak, wound
Indolence etc..Nephrotic syndrome severest consequences are exactly to cause acute renal failure；Caused by long-term High-grade Proteinuria
Chronic renal failure ratio is also far above normal population.
The main method of western medical treatment ephritis or renal dysfunction disease at present, it is to give patient's long-term steroid class medicine, this
Although a little hormone medicines can make the state of an illness of patient obtain respite, the purpose thoroughly effected a radical cure also is unable to reach.Moreover,
If patient largely uses hormone medicine for a long time, its caused side effect is very big, easily causes diabetes, hypertension, bone
Matter is loose, aseptic necrosis of bone, obesity, crinosity, acne, sodium retention, oedema, blood potassium reduction, gastrointestinal system disease, Nv Xingyue
Through illnesss such as disorders.Some patients can not only mitigate the pain that disease is brought, on the contrary because of the pair caused by hormone medicine
Effect, add the pain of patient.Therefore, in medical field, for hormone medicine side effect it is larger the problem of, caused
The great attention of medical experts, many doctors and scholar have started to explore and research and utilization Chinese medicine treatment renal system
Disease.
The content of the invention
According to above the deficiencies in the prior art, the technical problems to be solved by the invention are to propose that one kind treats nephrosis synthesis
Medicament of sign and preparation method thereof, by, from the Chinese herbal medicine of green natural, being decocted into liquid preparation by certain proportioning, being passed through
Oral liquid preparations, from interior conditioning body qi and blood, reach the effect for treating nephrotic syndrome.
To reach above-mentioned purpose, the present invention proposes a kind of medicament for treating nephrotic syndrome, includes the group of following parts by weight
Into composition：
7.5~30 parts of Radix Angelicae Sinensis, 7.5~30 parts of the root of herbaceous peony, 7.5~30 parts of the dried rhizome of rehmannia, 7.5~30 parts of Ligusticum wallichii, 5~20 parts of peach kernel,
7.5~30 parts of motherwort, 5~20 parts of safflower, 7.5~30 parts of dandelion, 10~40 parts of black snake, 7.5~30 parts of prepared fleece flower root, puncture
12.5~50 parts of lamb's-quarters, 3.5~14 parts of tag processed, 7.5~30 parts of Herba Ecliptae, 7.5~30 parts of the fruit of glossy privet, rhizoma imperatae 10~40
Part, 10~40 parts of cultivated land, 10~40 parts of Chinese yam, 12.5~50 parts of Fructus Corni, 3.5~14 parts of Chinese ephedra, 7.5~30 parts of kuh-seng, stone
25~100 parts of cream, 25~100 parts of the Radix Astragali.
Preferably, the medicament of above-mentioned treatment nephrotic syndrome includes the constituent of following parts by weight：
15 parts of Radix Angelicae Sinensis, 15 parts of the root of herbaceous peony, 15 parts of the dried rhizome of rehmannia, 15 parts of Ligusticum wallichii, 10 parts of peach kernel, 15 parts of motherwort, 10 parts of safflower, Pu Gong
15 parts of English, 20 parts of black snake, 15 parts of prepared fleece flower root, 25 parts of Fructus Tribuli, 7 parts of tag processed, 15 parts of Herba Ecliptae, 15 parts of the fruit of glossy privet, cogongrass
20 parts of root, 20 parts of cultivated land, 20 parts of Chinese yam, 25 parts of Fructus Corni, 7 parts of Chinese ephedra, 15 parts of kuh-seng, 50 parts of gypsum, 50 parts of the Radix Astragali.
The medicament formed using above-mentioned preferred component, the property of medicine is gentle, and efficiency high, directly and quickly can reach dissolving stasis and determine
Bitterly, the effect of nourishing Yin and clearing heat, so as to have the function that to treat nephrotic syndrome.
The present invention also proposes a kind of preparation method for the medicament for treating nephrotic syndrome, including following preparation process：
Step 1: choose Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root,
Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali, are washed
Only, dry；
Step 2: by it is above-mentioned clean, dried Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, Pu Gong
English, black snake, prepared fleece flower root, Fructus Tribuli, tag processed, early lotus, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng,
Gypsum and the Radix Astragali are placed in decoction vessel, and water is drunk raw in addition, is decocted, the medicament for the nephrotic syndrome that obtains medical treatment.
What head of Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, system in above-mentioned steps two
Crow, Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali
The Traditional Chinese drug mixture of composition and the solid-liquid ratio for drinking raw water are 1g:2~10ml.
Decoction vessel is marmite, ceramic pan, crock etc. in above-mentioned steps two, and the present invention can preferably make medicinal material and soup in pot
Juice is maintained at the state seethed with excitement slightly and does not change the marmite of the property of medicine as decoction vessel for a long time.
The condition decocted in above-mentioned steps two is that boiling water decocts 1~3h.
Radix Angelicae Sinensis is to belong to a kind of umbelliferous plant, and herbaceos perennial, the root of Radix Angelicae Sinensis can be used as medicine, typically be used for medicinal purpose, be
One of the most frequently used Chinese medicine, there is regulation body's immunity, replenishing and activating blood, antibacterial, anti arteriosclerosis and other effects.
The root of herbaceous peony is also referred to as white flower Chinese herbaceous peony, is young pilose antler section Chinese herbaceous peony platymiscium, has smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating etc.
Effect.
The dried rhizome of rehmannia is the root tuber of scrophulariaceae rehmannia glutinosa plant, has nourishing yin and nourishing blood, nourishing Yin and promoting production of body fluid, clearing heat and cooling blood and other effects.
Ligusticum wallichii is the dry rhizome of samphire Ligusticum wallichii, has promoting blood circulation and removing blood stasis, promote breath and open depression, wind-expelling pain-stopping and other effects.
Peach kernel is the seed of the drying and ripening of rosaceous plant peach or mountain peach, has dissolving stasis blood, anti-inflammatory, antiallergy, antibechic
And other effects.
Motherwort is mother wort plant, has promoting blood circulation, dissolving stasis, menstruation regulating, disappear water and other effects.
Safflower is also known as safflower, dicotyledon, has the effect of invigorate blood circulation and stasis-dispelling and pain-killing.
Dandelion also known as chrysanthemum seedling, herbaceos perennial, there is the effect of clearing heat and detoxicating and carbuncle that disappears dissipating bind.
Black snake also known as black colored snake, it is a kind of larger nonpoisonous snake of body, there is wind-dispelling, active, arresting convulsion and other effects.
Prepared fleece flower root is the processed goods of the fleece-flower root, has filling liver kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles and other effects.
Fructus Tribuli also known as puncture vine, seven lis of sons, there is flat liver solution strongly fragrant, promoting blood circulation by removing wind, improving eyesight, antipruritic and other effects.
Tag processed is the converted products of tag, has tonifying spleen and kidney, eliminating cold to stop pain, recuperating depleted yang and other effects.
Herba Ecliptae is annual herb plant, has cooling blood and hemostasis and nourishing liver and kidney effect.
Fruit of glossy privet alias glossy privet reality, purpleflower holly fruit, wax tree, it is the dry mature fruit of Oleaceae plants glossy privet, there is help
Liver kidney, improving eyesight, clearind deficient heat and other effects.
Rhizoma imperatae, Chinese medicine name.For the dry rhizome of grass cogongrass, there is the work(such as cool blood, hemostasis, reducing fever and causing diuresis
Effect.
Cultivated land is the root tuber of scrophulariaceae rehmannia glutinosa plant, also known as prepared rhizome of rehmannia or throws oneself on the ground, and processed processings forms, foster with enriching blood
The moon, life essence-filling, marrow-benefitting, anti-oxidant and other effects.
Chinese yam is also known as Chinese yam, native potato, sweet potato Chinese yam, RHIIZOMA DIOSCOREAE from Henan of China, Chinese yam, white Chinese yam, is《Chinese book on Chinese herbal medicine》The herbal medicine recorded, medicine
Be Dioscoreaceae plant Chinese yam dry rhizome with source, have nourish it is strong, aid digestion, hold back abnormal sweating, antidiarrheal and other effects.
Fructus Corni, Chinese medicine name.For the drying and ripening pulp of Cornaceae plant Fructus Corni, have to tonify the liver and kidney and consolidate with inducing astrigency
De- effect.
Chinese ephedra is the drying herbaceous stem stem of Ephedraceae plant ephedra sinica, epheday intermedia or ephedra equisetina, has sweating cold dispelling, facilitaing lung
Relieving asthma, inducing diuresis for removing edema and other effects.
Kuh-seng, Chinese medicine name, for the dry root of legume kuh-seng.The effect of with heat-clearing and damp-drying drug, desinsection, diuresis.
For gypsum inside the traditional Chinese medical science, medicinal gypsum is " gypsum ".Gypsum is also known as white tiger, microlith, is Sulfates ore deposit
Thing, acrid-sweet flavor cold in nature, to treat the common medicine of warm disease, there is the effect of heat-clearing expelling pathogenic factors from muscles and skin, relieving restlessness quench the thirst.
The Radix Astragali, also known as continuous stilbene, be herbaceos perennial, have enhancing body's immunity, liver protection, diuresis, anti-aging,
Resisting stress and decompression and other effects.
The present invention using Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root,
Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali
Synergy, Inner adjust body, and removing blood stasis and relieving pain, nourishing Yin and clearing heat, benefiting qi and nourishing blood and detumescence anti-inflammatory reach treatment nephrotic syndrome
Effect.
Present invention has the advantages that:Preparation technology is simple to operation；Selection is simplified, green non-pollution；The present invention is by medium-height grass
Medicinal material is ground to be decocted using marmite, is not only convenient for drinking, it is easier to absorption of human body, improves drug effect；Suitable therapeutic nephrosis of the present invention is comprehensive
Simulator sickness, curative for effect, effect significantly, safe ready and have no toxic side effect.
Embodiment
By the description to embodiment, to help those skilled in the art to have inventive concept of the invention, technical scheme
More complete, accurate and deep understanding.
The present invention proposes a kind of medicament for treating nephrotic syndrome, includes the constituent of following parts by weight：
7.5~30 parts of Radix Angelicae Sinensis, 7.5~30 parts of the root of herbaceous peony, 7.5~30 parts of the dried rhizome of rehmannia, 7.5~30 parts of Ligusticum wallichii, 5~20 parts of peach kernel,
7.5~30 parts of motherwort, 5~20 parts of safflower, 7.5~30 parts of dandelion, 10~40 parts of black snake, 7.5~30 parts of prepared fleece flower root, puncture
12.5~50 parts of lamb's-quarters, 3.5~14 parts of tag processed, 7.5~30 parts of Herba Ecliptae, 7.5~30 parts of the fruit of glossy privet, rhizoma imperatae 10~40
Part, 10~40 parts of cultivated land, 10~40 parts of Chinese yam, 12.5~50 parts of Fructus Corni, 3.5~14 parts of Chinese ephedra, 7.5~30 parts of kuh-seng, stone
25~100 parts of cream, 25~100 parts of the Radix Astragali.
The preparation method of the medicament of above-mentioned treatment nephrotic syndrome, including following preparation process：
Step 1: choose Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root,
Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali, are washed
Only, dry；
Step 2: by it is above-mentioned clean, dried Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, Pu Gong
English, black snake, prepared fleece flower root, Fructus Tribuli, tag processed, early lotus, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng,
The Traditional Chinese drug mixture of gypsum and Radix Astragali composition is placed in marmite, ceramic pan or crock decoction vessel, adds Traditional Chinese drug mixture and life
The solid-liquid ratio of drinking-water is 1g:2~10ml's drink raw water, decocts 1~3h, the medicament for the nephrotic syndrome that obtains medical treatment.
The present invention using Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root,
Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali
Synergy, Inner adjust body, and removing blood stasis and relieving pain, nourishing Yin and clearing heat, benefiting qi and nourishing blood and detumescence anti-inflammatory reach treatment nephrotic syndrome
Effect.
Embodiment one
On the basis of embodiment, the medicament of the treatment nephrotic syndrome of the present embodiment, including following parts by weight
Constituent：
Radix Angelicae Sinensis 15g, root of herbaceous peony 15g, dried rhizome of rehmannia 15g, Ligusticum wallichii 15g, peach kernel 10g, motherwort 15g, safflower 10g, dandelion 15g,
Black snake 20g, prepared fleece flower root 15g, Fructus Tribuli 25g, tag 7g processed, Herba Ecliptae 15g, fruit of glossy privet 15g, rhizoma imperatae 20g, cultivated land 20g,
Chinese yam 20g, Fructus Corni 25g, Chinese ephedra 7g, kuh-seng 15g, gypsum 50g, Radix Astragali 50g.
The preparation method of the medicament of above-mentioned treatment nephrotic syndrome, including following preparation process：
Step 1: choose Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root,
Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali, are washed
Only, dry；
Step 2: by it is above-mentioned clean, dried Radix Angelicae Sinensis 15g, root of herbaceous peony 15g, dried rhizome of rehmannia 15g, Ligusticum wallichii 15g, peach kernel 10g, benefit
Brittle Falsepimpernel Herb 15g, safflower 10g, dandelion 15g, black snake 20g, prepared fleece flower root 15g, Fructus Tribuli 25g, tag 7g processed, Herba Ecliptae 15g, female
Loyal sub- 15g, rhizoma imperatae 20g, cultivated land 20g, Chinese yam 20g, Fructus Corni 25g, Chinese ephedra 7g, kuh-seng 15g, gypsum 50g, Radix Astragali 50g groups
Into Traditional Chinese drug mixture be placed in marmite, add 1242ml drink raw water, decoct 2h, the medicament for the nephrotic syndrome that obtains medical treatment.
Embodiment two
On the basis of embodiment, the medicament of the treatment nephrotic syndrome of the present embodiment, including following parts by weight
Constituent：
Radix Angelicae Sinensis 7.5g, root of herbaceous peony 7.5g, dried rhizome of rehmannia 7.5g, Ligusticum wallichii 30g, peach kernel 30g, motherwort 30g, safflower 15g, dandelion
20g, black snake 30g, prepared fleece flower root 30g, Fructus Tribuli 20g, tag 7g processed, Herba Ecliptae 20g, fruit of glossy privet 20g, rhizoma imperatae 20g, cultivated land
20g, Chinese yam 25g, Fructus Corni 25g, Chinese ephedra 7g, kuh-seng 20g, gypsum 60g, Radix Astragali 60g.
The preparation method of the medicament of above-mentioned treatment nephrotic syndrome, including following preparation process：
Step 1: choose Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root,
Fructus Tribuli, tag processed, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali, are washed
Only, dry；
Step 2: by it is above-mentioned clean, dried Radix Angelicae Sinensis 15g, root of herbaceous peony 15g, dried rhizome of rehmannia 15g, Ligusticum wallichii 15g, peach kernel 10g, benefit
Brittle Falsepimpernel Herb 15g, safflower 10g, dandelion 15g, black snake 20g, prepared fleece flower root 15g, Fructus Tribuli 25g, tag 7g processed, Herba Ecliptae 15g, female
Loyal sub- 15g, rhizoma imperatae 20g, cultivated land 20g, Chinese yam 20g, Fructus Corni 25g, Chinese ephedra 7g, kuh-seng 15g, gypsum 50g, Radix Astragali 50g groups
Into Traditional Chinese drug mixture be placed in marmite, add 2046ml drink raw water, decoct 3h, the medicament for the nephrotic syndrome that obtains medical treatment.
Drinking method of the present invention：Every dose is drunk 2 days, is drunk daily 3 times, each 200-350 milliliters.
Patient：Mr. Cheng, 21 years old.
Illness symptom：Arteries and veins is shown in qi-blood deficiency, kidney insufficiency edema from head to foot, goes to hospital to examine for nephrotic syndrome, has taken doctor
Institute, which writes a prescription 3 months to swell, not to disappear, and 3 plus siges of Urine proteins, occasionally there is blood urine.
Treatment：The medicament Inner of above example one is given to recuperate under medical treatment reason, every dose is drunk 2 days, is drunk 3 times, 207 milliliters every time, is taken daily
After medicine 6 months, all diseases are all cured, and have been discontinued.
Patient：Mrs Li, 25 years old.
Illness symptom：Had a fever after drenching with rain, from head to foot edema, examine to burn within 7 days through transfusion for acute nephritis in hospital and move back, it is swollen not disappear,
There is blood urine albuminuria.
Treatment：The medicament Inner of above example one is given to recuperate under medical treatment reason, every dose is drunk 2 days, is drunk daily 3 times, every time 207 milliliters；3 doses
It is swollen to disappear, 3 doses of blood urine albuminuria are taken again and are disappeared, and recovery from illness is discontinued.
Patient：Mr. Wang, 23 years old.
Illness symptom：After flu again drunk induction acute pyelonephritis, edema, blood urine albuminuria, renal dysfunction, in many ways
Face is cured and not felt any better, and arteries and veins is shown in liver stomach energy, kidney-yin deficiency.
Treatment：The medicament Inner of above example one is given to recuperate under medical treatment reason, every dose is drunk 2 days, is drunk daily 3 times, every time 207 milliliters；Clothes
After medicament with 10 doses of embodiments one, recovery from illness is discontinued.
The present invention is exemplarily described above, it is clear that present invention specific implementation is not subject to the restrictions described above,
As long as employing the improvement of the various unsubstantialities of inventive concept and technical scheme of the present invention progress, or not improved this is sent out
Bright design and technical scheme directly applies to other occasions, within protection scope of the present invention.The protection of the present invention
Scope should be determined by the scope of protection defined in the claims.
Claims (6)
1. a kind of medicament for treating nephrotic syndrome, it is characterised in that include the constituent of following parts by weight：
7.5~30 parts of Radix Angelicae Sinensis, 7.5~30 parts of the root of herbaceous peony, 7.5~30 parts of the dried rhizome of rehmannia, 7.5~30 parts of Ligusticum wallichii, 5~20 parts of peach kernel, benefit are female
7.5~30 parts of grass, 5~20 parts of safflower, 7.5~30 parts of dandelion, 10~40 parts of black snake, 7.5~30 parts of prepared fleece flower root, Fructus Tribuli
12.5~50 parts, it is 3.5~14 parts of tag processed, 7.5~30 parts of Herba Ecliptae, 7.5~30 parts of the fruit of glossy privet, 10~40 parts of rhizoma imperatae, ripe
10~40 parts of ground, 10~40 parts of Chinese yam, 12.5~50 parts of Fructus Corni, 3.5~14 parts of Chinese ephedra, 7.5~30 parts of kuh-seng, gypsum 25~
100 parts, 25~100 parts of the Radix Astragali.
2. the medicament for the treatment of nephrotic syndrome according to claim 1, it is characterised in that：The treatment nephrotic syndrome
Medicament includes the constituent of following parts by weight：
15 parts of Radix Angelicae Sinensis, 15 parts of the root of herbaceous peony, 15 parts of the dried rhizome of rehmannia, 15 parts of Ligusticum wallichii, 10 parts of peach kernel, 15 parts of motherwort, 10 parts of safflower, dandelion 15
Part, 20 parts of black snake, 15 parts of prepared fleece flower root, 25 parts of Fructus Tribuli, 7 parts of tag processed, 15 parts of Herba Ecliptae, 15 parts of the fruit of glossy privet, rhizoma imperatae 20
Part, 20 parts of cultivated land, 20 parts of Chinese yam, 25 parts of Fructus Corni, 7 parts of Chinese ephedra, 15 parts of kuh-seng, 50 parts of gypsum, 50 parts of the Radix Astragali.
3. the preparation method of the medicament for the treatment of nephrotic syndrome according to claim 1, it is characterised in that：The preparation side
Method includes following preparation process：
Step 1: choose Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root, puncture vine
Son, tag, Herba Ecliptae, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali processed, clean,
Dry；
Step 2: by it is above-mentioned clean, dried Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, crow
Snake, prepared fleece flower root, Fructus Tribuli, tag processed, early lotus, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum
And the Radix Astragali is placed in decoction vessel, water is drunk raw in addition, is decocted, the medicament for the nephrotic syndrome that obtains medical treatment.
4. the preparation method of the medicament for the treatment of nephrotic syndrome according to claim 3, it is characterised in that：The step 2
Middle Radix Angelicae Sinensis, the root of herbaceous peony, the dried rhizome of rehmannia, Ligusticum wallichii, peach kernel, motherwort, safflower, dandelion, black snake, prepared fleece flower root, Fructus Tribuli, tag processed, morning
The Traditional Chinese drug mixture and life that lotus, the fruit of glossy privet, rhizoma imperatae, cultivated land, Chinese yam, Fructus Corni, Chinese ephedra, kuh-seng, gypsum and the Radix Astragali form
The solid-liquid ratio of drinking-water is 1g:2~10ml.
5. the preparation method of the medicament for the treatment of nephrotic syndrome according to claim 3, it is characterised in that：The step 2
Middle decoction vessel is marmite.
6. the preparation method of the medicament for the treatment of nephrotic syndrome according to claim 3, it is characterised in that：The step 2
In the condition that decocts decoct 1~3h for boiling water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710434387.5A CN107334963A (en) | 2017-06-09 | 2017-06-09 | A kind of medicament for treating nephrotic syndrome and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710434387.5A CN107334963A (en) | 2017-06-09 | 2017-06-09 | A kind of medicament for treating nephrotic syndrome and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107334963A true CN107334963A (en) | 2017-11-10 |
Family
ID=60220553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710434387.5A Pending CN107334963A (en) | 2017-06-09 | 2017-06-09 | A kind of medicament for treating nephrotic syndrome and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107334963A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108079206A (en) * | 2017-12-05 | 2018-05-29 | 安徽维力拓网络科技有限公司 | Alleviate decoction of nephrotic syndrome and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050276872A1 (en) * | 2001-08-31 | 2005-12-15 | Chan Pui-Kwong | Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
| CN104857455A (en) * | 2015-06-12 | 2015-08-26 | 陈传英 | Traditional Chinese medicine preparation for chronic interstitial nephropathy and preparation method thereof |
| CN106798907A (en) * | 2017-03-05 | 2017-06-06 | 牛健坤 | It is a kind of to treat medicine of nephrotic syndrome and preparation method thereof |
-
2017
- 2017-06-09 CN CN201710434387.5A patent/CN107334963A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050276872A1 (en) * | 2001-08-31 | 2005-12-15 | Chan Pui-Kwong | Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof |
| CN104857455A (en) * | 2015-06-12 | 2015-08-26 | 陈传英 | Traditional Chinese medicine preparation for chronic interstitial nephropathy and preparation method thereof |
| CN106798907A (en) * | 2017-03-05 | 2017-06-06 | 牛健坤 | It is a kind of to treat medicine of nephrotic syndrome and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 支艳等: "补肾健脾活血利水方治疗肾病综合征30例", 《现代中西医结合杂志》 * |
| 赵亮等: "肾病综合症治验", 《中医函授通讯》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108079206A (en) * | 2017-12-05 | 2018-05-29 | 安徽维力拓网络科技有限公司 | Alleviate decoction of nephrotic syndrome and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101284105A (en) | Thrombolysis lipid-lowering pellet for curing cardio-cerebrovascular disease | |
| CN102755596B (en) | Traditional Chinese medicine for treating phlegm-dampness hyperplasia of mammary glands and preparation method thereof | |
| CN108030864A (en) | A kind of strong medicine liquid for treating traumatic injury, burn and inflammation | |
| CN104013868B (en) | Traditional Chinese medicine composition for treating chronic obstructive pulmonary disease and preparation method thereof | |
| CN104324340B (en) | It is a kind of to treat Chinese medicine preparation of heel bone hyperosteogeny and preparation method thereof | |
| CN105250890A (en) | Traditional Chinese medicine for treating hyperlipidemia | |
| CN103656276B (en) | Medicine for the treatment of renal failure and preparation method thereof | |
| CN102579799B (en) | Traditional Chinese medicine composition for treating postpartum fever with blood deficiency | |
| CN107334963A (en) | A kind of medicament for treating nephrotic syndrome and preparation method thereof | |
| CN101934016B (en) | External medicament for treating arthritis | |
| CN112972557A (en) | Medicinal liquor for treating arthralgia and myalgia and preparation method thereof | |
| CN105055931A (en) | Traditional Chinese medicine preparation for treating chronic obstructive pulmonary disease | |
| CN104758701A (en) | Medicament for nursing treatment of stomach stones after lithotripsy and preparation method of medicament | |
| CN104623532A (en) | Traditional Chinese medicine composition for treating glioma and preparation method thereof | |
| CN103705727A (en) | Chinese medicinal composition for treating diabetes | |
| CN103566245B (en) | A kind of medicine for the treatment of nephropathy | |
| CN100998720B (en) | Oral traditional Chinese medicine for treating amenorrhea of uterus stasis | |
| CN107373666A (en) | A kind of Chinese herbal medicine benefiting qi and nourishing blood food additives and preparation method thereof | |
| CN105998860A (en) | A kind of traditional Chinese medicine composition for treating osteoarthritis | |
| CN106729256A (en) | It is a kind of to treat lavipeditum powder of arthralgia pain due to rheumatism and preparation method thereof | |
| CN105709099A (en) | Nose drop for relieving nasal polyp symptom and preparation method | |
| CN105169277A (en) | Fructus gardeniae oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof | |
| CN105031335A (en) | Medicament for nursing and treatment after microwave pulverization of gastric bezoars and its preparation method | |
| CN103830612A (en) | Traditional Chinese medicine composition for treating tinea manus and tinea pedis | |
| CN110368437A (en) | A kind of Chinese medicine composition for removing anaphylactoid purpura |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171110 |