CN106983574A - A kind of small balloon-system of zoopery heart infarction model and preparation method - Google Patents
A kind of small balloon-system of zoopery heart infarction model and preparation method Download PDFInfo
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- CN106983574A CN106983574A CN201710315463.0A CN201710315463A CN106983574A CN 106983574 A CN106983574 A CN 106983574A CN 201710315463 A CN201710315463 A CN 201710315463A CN 106983574 A CN106983574 A CN 106983574A
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- sacculus
- tracheae
- zoopery
- heart infarction
- infarction model
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Surgical Instruments (AREA)
Abstract
The present invention discloses a kind of small balloon-system of zoopery heart infarction model, including tracheae, sacculus and aerating device, and sacculus is located at tracheae one end, and aerating device is located at the tracheae other end；The volume of sacculus is not more than 0.1 milliliter, and the caliber of tracheae is not more than 0.4 millimeter.Invention additionally discloses a kind of preparation method of the small balloon-system of zoopery heart infarction model, including step 1：Aerating device is sealingly connected to tracheae one end；Step 2：The other end of tracheae is knotted, and is locally heated to tracheomalacia；Step 3：Using 1~2 milliliter of air of aerating device injection, sacculus is formed；Step 4：Cool down aftershaping and sacculus edge pruning is clean.The balloon-system carries out inflation manually using pipeline connection syringe and deflated, and is oppressed coronary artery and released compressing, play the purpose of Basilar artery coronary blood flow.
Description
Technical field
The present invention relates to animal pathology model experiment clothing arts, and in particular to a kind of small ball of zoopery heart infarction model
Bag apparatus and preparation method.
Background technology
Myocardial infarction pathological model is most common zoopery surgical procedures technology, using widely.Due to petty action
Thing (rat, mouse) heart is small (size is generally 7~10 millimeters of major diameter, 3-5 millimeters of transverse diameter), and coronary artery is fine, in ligation
Difficulty is big when branch of coronary artery, and modeling success rate is low, while easily damaged coronary in itself, causes coronary artery after ligature knotting
Permanent occlusion, it is impossible to reflect human body heart infarction ischemia and reperfusion process completely.At present can only be careful by surgical technic personnel
Operation, it is to avoid loss, improves success rate.
The content of the invention
Goal of the invention：The technical problems to be solved by the invention are can to enter there is provided one kind in view of the shortcomings of the prior art
The small balloon-system of zoopery heart infarction model of the manual inflation-deflation of row.
In order to solve the above-mentioned technical problem, the invention discloses a kind of small balloon-system of zoopery heart infarction model, bag
Tracheae, sacculus and aerating device are included, the sacculus is located at tracheae one end, and the aerating device is located at the tracheae other end；It is described
The volume of sacculus is not more than 0.1 milliliter, and the caliber of tracheae is not more than 0.4 millimeter.
It is further preferred that the sacculus both sides are provided with fixed-wing, the fixed-wing is provided with positioning hole.
It is further preferred that the aerating device is syringe.
It is further preferred that the volume of the sacculus is not more than 0.06 milliliter.
It is further preferred that the maximum sphere diameter of the sacculus is not more than 3 millimeters.
The invention also discloses a kind of preparation method of the small balloon-system of zoopery heart infarction model, including following step
Suddenly：
Step 1：Aerating device is sealingly connected to tracheae one end；
Step 2：The other end of tracheae is knotted, and is locally heated to tracheomalacia；
Step 3：Using 1~2 milliliter of air of aerating device injection, sacculus is formed；
Step 4：Cool down aftershaping and sacculus edge pruning is clean, knotting position can be trimmed.
Wherein, including step 5, sacculus is lived using plastic film wrapped, and leaves two flanks, punched on two flanks, formed
Fixed-wing, animal hearts coronary artery conduct surface is fixed on by fixed-wing by sacculus.
Wherein, local heating described in step 2 is using one kind in immersion hot water or laser heating.
Wherein, aerating device described in step 1 is syringe.
Wherein, the specific scope of local heating described in step 2 is from knotting upward 3~5 millimeters, it is ensured that sacculus quilt completely
Heating.
Beneficial effect：The present apparatus carries out manual inflation-deflation using pipeline connection syringe, and experimental mouse heart coronary artery is entered
Row compressing and releasing compressing, play the purpose of Basilar artery coronary blood flow.
Brief description of the drawings
The present invention is done with reference to the accompanying drawings and detailed description and further illustrated, of the invention is above-mentioned
And/or otherwise advantage will become apparent.
Fig. 1 is the structural representation of the present apparatus.
Embodiment
As shown in figure 1, the present apparatus includes tracheae 1, the sacculus 2 positioned at the one end of tracheae 1 and the injection positioned at the other end of tracheae 1
Device 3；The volume of sacculus 2 is 0.05 milliliter, and the caliber of tracheae is 0.25 millimeter；The both sides of sacculus 2 are provided with fixed-wing 4, fixed-wing 4
Provided with positioning hole 5.
A kind of preparation method step of the small balloon-system of zoopery heart infarction model of the present embodiment includes：
The first step：Syringe 3 is sealingly connected to the one end of tracheae 1, the gas injection rate (2 milliliters) of syringe 3 is set；
Second step：The other end of tracheae 1 is knotted, and upward 3 millimeters of immersions hot water heating at knotting is soft to tracheae 1
Change；
3rd step：Using 2 milliliters of air of the injection of syringe 3, the sacculus 2 that maximum sphere diameter is not more than 3 millimeters is formed；
4th step：Cool down aftershaping and the edge pruning of sacculus 2 is totally formed into the smooth sacculus with tracheae；
5th step：Sacculus 2 is lived using plastic film wrapped, and leaves two flanks, positioning hole 5 is beaten on two flanks, forms solid
Determine the wing 4, the suture of film fixed-wing 4 is connected to sacculus periphery using 8-0 nylon yarn.
During using the present embodiment product, sacculus 2 is fixed on by animal hearts coronary artery conduct surface by fixed-wing 4, formed
Embolism, only air-breathing need to be carried out when releasing embolism by syringe 3.Implement quick heart infarction reality in meiofauna heart so as to solve
Test the technical problem of simultaneously fast quick-recovery.
The invention provides a kind of small balloon-system of zoopery heart infarction model and the thinking and method of preparation method, tool
Body realizes that the method and approach of the technical scheme are a lot, and described above is only the preferred embodiment of the present invention, it is noted that right
For those skilled in the art, under the premise without departing from the principles of the invention, some improvement can also be made
And retouching, these improvements and modifications also should be regarded as protection scope of the present invention.Each part being not known in the present embodiment is equal
It can be realized with prior art.
Claims (10)
1. a kind of small balloon-system of zoopery heart infarction model, it is characterised in that including tracheae (1), sacculus (2) and inflation
Device, the sacculus (2) is located at tracheae (1) one end, and the aerating device is located at tracheae (1) other end；The appearance of the sacculus (2)
Product is not more than 0.1 milliliter, and the caliber of tracheae (1) is not more than 0.4 millimeter.
2. a kind of small balloon-system of zoopery heart infarction model according to claim 1, it is characterised in that the sacculus
(2) both sides are provided with fixed-wing (4)；The fixed-wing (4) is provided with positioning hole (5).
3. a kind of small balloon-system of zoopery heart infarction model according to claim 1, it is characterised in that the inflation
Device is syringe (3).
4. a kind of small balloon-system of zoopery heart infarction model according to claim 1, it is characterised in that the sacculus
(2) volume is not more than 0.06 milliliter.
5. a kind of small balloon-system of zoopery heart infarction model according to claim 1, it is characterised in that the sacculus
(2) maximum sphere diameter is not more than 3 millimeters.
6. a kind of preparation method of the small balloon-system of zoopery heart infarction model, it is characterised in that comprise the following steps：
Step 1：Aerating device is sealingly connected to tracheae (1) one end；
Step 2：The other end of tracheae (1) is knotted, and is locally heated to tracheae (1) softening；
Step 3：Using 1~2 milliliter of air of aerating device injection, sacculus (2) is formed；
Step 4：Cool down aftershaping and sacculus (2) edge pruning is clean.
7. a kind of preparation method of small balloon-system of zoopery heart infarction model according to claim 6, its feature exists
In, including step 5, sacculus (2) is lived using plastic film wrapped, and two flanks are left, punched on two flanks, form fixed-wing
(4)。
8. a kind of preparation method of small balloon-system of zoopery heart infarction model according to claim 6, its feature exists
In in the step 2, local heating is using one kind in immersion hot water or laser heating.
9. a kind of preparation method of small balloon-system of zoopery heart infarction model according to claim 6, its feature exists
In the aerating device is syringe (3).
10. a kind of preparation method of small balloon-system of zoopery heart infarction model according to claim 6, its feature exists
In in step 2, the specific scope of local heating is from knotting upward 3~5 millimeters.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2017103016503 | 2017-05-02 | ||
| CN201710301650 | 2017-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106983574A true CN106983574A (en) | 2017-07-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710315463.0A Pending CN106983574A (en) | 2017-05-02 | 2017-05-08 | A kind of small balloon-system of zoopery heart infarction model and preparation method |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1040742A (en) * | 1989-09-23 | 1990-03-28 | 复旦大学 | The making of medical polyethylene dilating sacculus |
| CN201005867Y (en) * | 2007-03-27 | 2008-01-16 | 常勇刚 | Disposable medical inflatable pressurized pad pasting |
| CN101156805A (en) * | 2007-11-09 | 2008-04-09 | 浙江医院 | Establishing beagle dog myocardial infarction model using polythene foam plugging method |
| US20090096134A1 (en) * | 2004-01-07 | 2009-04-16 | Boston Scientific Scimed, Inc. | Process and Apparatus for Forming Medical Device Balloons |
| CN201519359U (en) * | 2009-10-21 | 2010-07-07 | 李胜活 | Balloon vessel blocking pipe for blocking and re-perfusing middle cerebral artery in rats |
| CN101966334A (en) * | 2010-09-29 | 2011-02-09 | 北京泰德制药股份有限公司 | Application of lecithin superoxide dismutase composite in preparation of medicines for treating and/or preventing cardiac ischemic injury |
| CN202821496U (en) * | 2012-10-31 | 2013-03-27 | 纪淑娟 | Balloon catheter used for open heart surgery in Cardiology Department |
| CN204636455U (en) * | 2015-04-30 | 2015-09-16 | 中国人民解放军第三军医大学第一附属医院 | For Choanal hemostasis device |
| CN205084183U (en) * | 2015-11-10 | 2016-03-16 | 朱军 | Intracardiac branch of academic or vocational study sacculus pipe |
-
2017
- 2017-05-08 CN CN201710315463.0A patent/CN106983574A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1040742A (en) * | 1989-09-23 | 1990-03-28 | 复旦大学 | The making of medical polyethylene dilating sacculus |
| US20090096134A1 (en) * | 2004-01-07 | 2009-04-16 | Boston Scientific Scimed, Inc. | Process and Apparatus for Forming Medical Device Balloons |
| CN201005867Y (en) * | 2007-03-27 | 2008-01-16 | 常勇刚 | Disposable medical inflatable pressurized pad pasting |
| CN101156805A (en) * | 2007-11-09 | 2008-04-09 | 浙江医院 | Establishing beagle dog myocardial infarction model using polythene foam plugging method |
| CN201519359U (en) * | 2009-10-21 | 2010-07-07 | 李胜活 | Balloon vessel blocking pipe for blocking and re-perfusing middle cerebral artery in rats |
| CN101966334A (en) * | 2010-09-29 | 2011-02-09 | 北京泰德制药股份有限公司 | Application of lecithin superoxide dismutase composite in preparation of medicines for treating and/or preventing cardiac ischemic injury |
| CN202821496U (en) * | 2012-10-31 | 2013-03-27 | 纪淑娟 | Balloon catheter used for open heart surgery in Cardiology Department |
| CN204636455U (en) * | 2015-04-30 | 2015-09-16 | 中国人民解放军第三军医大学第一附属医院 | For Choanal hemostasis device |
| CN205084183U (en) * | 2015-11-10 | 2016-03-16 | 朱军 | Intracardiac branch of academic or vocational study sacculus pipe |
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Application publication date: 20170728 |
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