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CN106937980A - It is a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof - Google Patents

It is a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof Download PDF

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Publication number
CN106937980A
CN106937980A CN201710199854.0A CN201710199854A CN106937980A CN 106937980 A CN106937980 A CN 106937980A CN 201710199854 A CN201710199854 A CN 201710199854A CN 106937980 A CN106937980 A CN 106937980A
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Prior art keywords
cold
composition
rheumatism
decoction
dampness
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李邦富
李劲诚
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Guizhou Silver Lao Dong Pharmaceutical Co Ltd
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Guizhou Silver Lao Dong Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

It is more particularly to a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof the present invention relates to drug preparation technique field;Including following raw material by weight:Herba Senecionis Scandentis 80~120, ramulus mori 80~120, cassia twig 180~220, smelly goat 80~120, willow skin 80~120, mulberry skin 45~55, yncaria stem with hooks 45~55, notopterygium root 70~80, levisticum 70~80;The preparation of the present invention passes through with clearing heat and detoxicating, it is promoting blood circulation and removing blood stasis, wind-damp dispelling, detumescence, the medicine of analgesic efficacy are combined, so that composition, which has, promotes channels and collaterals, blood circulation, effect promoting blood circulation and removing blood stasis, reaches the purpose for the treatment of rheumatism cold-dampness disease, composition of the invention, its therapeutic effect is notable, clinical improvement rate, while avoiding the pain brought using doctor trained in Western medicine and physiotherapy to patient, is had no side effect more than 88% after treatment, it is uneasy to recur, and it is easy to operate, while selected Chinese medicine material is readily available, and human body is had no toxic side effect.

Description

It is a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof
Technical field
It is more particularly to a kind of to treat rheumatism, the composition of cold-dampness disease and its system the present invention relates to drug preparation technique field Preparation Method.
Background technology
The traditional Chinese medical science thinks that with the passing of time rheumatism do not understood, and will go deep into muscles and bones, and it enters also deeply, and the sluggish passages through which vital energy circulates of damp evil, causes the stasis of blood stagnant in addition Linger on, be not cured for a long time, clinically, this sick common limbs arthralgia and myalgia is numb, very then joint stuffiness, it, which is controlled, is difficult to produce effects immediately, When search wind dehumidifying, with Xiao Huoluo Dan long term usage it, its effect is favourable;Cold-dampness person, is that cold to close with wetting phase and invade human body be disease.Cold-dampness All it is cloudy heresy, therefore, all with the feature for damaging human body, because infestation position is different, so clinical manifestation is different, it is such as cold Wet to attack people's fleshy exterior, table sun is strongly fragrant, just there is fever with chilliness, and pain head body weight, lossless, arthralgia, the warm chilly of happiness, weather cold sensation of the genitalia then adds Weight, tongue is greasy in vain, floating and tense pulse or floating slow etc., limbs are violated rheumatism more, and heresy has exterior deficiency, table reality to divide, table reality person is pure in fleshy exterior person The card of reality;Exterior deficiency person is actual situation and miscellaneous time, and its heresy gos deep into muscles and bones person, control it is more difficult take effect, cold-dampness can both have been violated and limbs, also Can violate and internal organ, and per injuring the yang-energy of carcass more, it is damp and hot violate taste, its control when by it is wet with it is hot how many and control it.
At present, doctor trained in Western medicine for the wet disease of chill treatment more the medicine that uses based on antibiotic, hormone, anodyne, reason Treat with partial insulation, physiotherapy, acupuncture, massage, though so contributing to rapid recovery, slow down pain, its short run effect is fine, Root can not be removed, drug therapy is carried out for the more long patient of stadium, but prolonged administration of drugs can not only develop immunity to drugs, also Gastrointestinal function damage, osteoporosis, endocrine disturbance, nervous system disorders and cortin hyperfunction etc. can be produced bad Reaction, and root can not be thoroughly removed, and use physiotherapy, then need to adhere to for a long time, it is impossible to interrupt, but be not easy to effect a radical cure, and due to Tcm therapy has Small side effects, and anti-recurrence rate effect is good, can the stable state of an illness, indiffusible feature so that it is in the wet disease of chill Sick field has obtained quick application and popularization.
But, because the traditional Chinese medical science of the prior art formula is unreasonable, material composition is incorrect, causes the wet disease of current chill Therapeutic effect it is not notable, cure rate is relatively low, and there is the Chinese medicine preparation of the research treatment wet disease of chill the current country, and achieves one The invention of fixed effect, such as application number CN201410574266.7《Control the Chinese medicine preparation of wind cold wetness type gout》Disclose river processed Black 10-15 grams, 10-15 grams of the root of herbaceous peony, 15-20 grams of cassia twig, 20-25 grams of the bighead atractylodes rhizome, the Chinese medicine preparation treatment chill of 10-15 grams of tetrandra root is wet Disease;But, because the traditional Chinese medical science of the prior art formula is unreasonable, material composition is incorrect, causes the wet disease of current chill Therapeutic effect is not notable, and improvement rate is relatively low.
The content of the invention
The present invention there is provided a kind of in order to solve the above technical problems, treat rheumatism, the composition of cold-dampness disease and its preparation side Method.
Realized particular by following technical scheme:
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 80~120, mulberry Branch 80~120, cassia twig 180~220, smelly goat 80~120, willow skin 80~120, mulberry skin 45~55, yncaria stem with hooks 45~55, notopterygium root 70~80, levisticum 70~80.
Preferably, including following raw material by weight:Herba Senecionis Scandentis 100, ramulus mori 100, cassia twig 200, smelly goat 100, Willow skin 100, mulberry skin 50, yncaria stem with hooks 50, notopterygium root 75, levisticum 75.
Described composition, preferably external used medicine.
Described composition, is dipping bath decoction.
The preparation method of the sick composition of described treatment rheumatism, cold-dampness, is by Herba Senecionis Scandentis, ramulus mori, cassia twig, smelly goat, poplar After willow bark, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing adds water, first decocted with big fire to boiling, then keeps micro- with small fire Boiling 30~40min of state, filtering, obtains decoction.
The composition of described treatment rheumatism, cold-dampness disease, its application method, be by pan-fried well-done decoction through natural cooling or Person adds cold decoction and blent, and regulation temperature is 38~42 DEG C, allows patient to be immersed in patient after 40~60min in decoction, bath Can not dry, allow with decoction and sweat spontaneously dry.
The composition of described treatment rheumatism, cold-dampness disease, in use, when carrying out temperature adjustment to decoction, it is impossible to add Hot water or cold water, will add cold decoction or medicine of a warm nature liquid carries out temperature adjustment.
Described composition, can also be prepared into oral formulations, including steep in wine, pill, tablet, capsule.
Described steeps in wine, and is after raw material is cleaned, to be sealed and soaked with white wine, 15d is at least soaked in summer, in the winter time at least Soak 30d.
Described pill, is to weigh raw material, is cleaned, and is crushed, and adds 18~25% pregelatinized starch of total amount, then is used 75% ethanol infiltration, by granulator granulation, is made particle, sieves, obtain pill.
Described tablet, is after raw material is weighed, to clean, crushes, add water to cook into the medicinal extract that water content is 12~15%, 18~25% amylum pregelatinisatum of medicinal extract quality is added, then is infiltrated with 65% ethanol, 0.5% stearic acid of total amount is added Magnesium is mixed, tabletted by tablet press machine, obtains tablet.
Described capsule, is to weigh raw material, is cleaned, and is crushed, then with methylcellulose or alginates or poly- second Capsulae vacuus prepared by enol or metagelatin is wrapped up, and is prepared into capsule.
Described oral liquid, is after raw material is weighed, to clean, add water infusion, adds the second of 5 times of amounts of filtrate gross mass Alcohol, is reclaimed after ethanol, and the sugar content of regulation residual solution is 20~30%, packaging.
In summary, the beneficial effects of the present invention are:The preparation of the present invention is promoting blood circulation and removing blood stasis by with clearing heat and detoxicating, Wind-damp dispelling, detumescence, the medicine of analgesic efficacy are combined so that composition, which has, promotes channels and collaterals, blood circulation, promoting blood circulation and removing blood stasis Effect, reaches the purpose for the treatment of rheumatism cold-dampness disease, and composition of the invention, its therapeutic effect is notable, and clinical improvement rate is 88% More than, while avoiding the pain brought using doctor trained in Western medicine and physiotherapy to patient, had no side effect after treatment, it is uneasy to recur, and operation Simplicity, while selected Chinese medicine material is readily available, and has no toxic side effect to human body.
The present composition is treated using the form of dipping bath decoction to patient, can be carried out for patient affected part rapidly straight The treatment connect, significantly, improvement rate is high for effect.
Embodiment
The embodiment to the present invention is described in further detail below, but the invention is not limited in these realities Mode is applied, any improvement or replacement on the present embodiment essence spirit still falls within the claims in the present invention claimed Scope.
Embodiment 1
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 80g, ramulus mori 80g, cassia twig 180g, smelly goat 80g, willow skin 80g, mulberry skin 45g, yncaria stem with hooks 45g, notopterygium root 70g, levisticum 70g.
The preparation method of the sick composition of described treatment rheumatism, cold-dampness, is by Herba Senecionis Scandentis, ramulus mori, cassia twig, smelly goat, poplar After willow bark, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing adds water, first decocted with big fire to boiling, then keeps micro- with small fire Boiling state 30min, filtering, obtains decoction.
The composition of described treatment rheumatism, cold-dampness disease, its application method, be by pan-fried well-done decoction through natural cooling or Person adds cold decoction and blent, and regulation temperature is 38 DEG C, and allowing patient to be immersed in patient after 40min in decoction, bath can not dry, Decoction and sweat with allowing are spontaneously dried.
Embodiment 2
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 120g, ramulus mori 120g, cassia twig 220g, smelly goat 120g, willow skin 120g, mulberry skin 55g, yncaria stem with hooks 55g, notopterygium root 80g, levisticum 80g.
The preparation method of the sick composition of described treatment rheumatism, cold-dampness, is by Herba Senecionis Scandentis, ramulus mori, cassia twig, smelly goat, poplar After willow bark, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing adds water, first decocted with big fire to boiling, then keeps micro- with small fire Boiling state 40min, filtering, obtains decoction.
The composition of described treatment rheumatism, cold-dampness disease, its application method, be by pan-fried well-done decoction through natural cooling or Person adds cold decoction and blent, and regulation temperature is 42 DEG C, and allowing patient to be immersed in patient after 60min in decoction, bath can not dry, Decoction and sweat with allowing are spontaneously dried.
Embodiment 3
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 100g, ramulus mori 100g, cassia twig 200g, smelly goat 100g, willow skin 100g, mulberry skin 50g, yncaria stem with hooks 50g, notopterygium root 75, levisticum 75g.
The preparation method of the sick composition of described treatment rheumatism, cold-dampness, is by Herba Senecionis Scandentis, ramulus mori, cassia twig, smelly goat, poplar After willow bark, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing adds water, first decocted with big fire to boiling, then keeps micro- with small fire Boiling state 35min, filtering, obtains decoction.
The composition of described treatment rheumatism, cold-dampness disease, its application method, be by pan-fried well-done decoction through natural cooling or Person adds cold decoction and blent, and regulation temperature is 40 DEG C, and allowing patient to be immersed in patient after 50min in decoction, bath can not dry, Decoction and sweat with allowing are spontaneously dried.
Embodiment 4
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 80g, ramulus mori 80g, cassia twig 220g, smelly goat 80g, willow skin 120g, mulberry skin 55g, yncaria stem with hooks 45g, notopterygium root 80g, levisticum 70g.
The preparation method of the sick composition of described treatment rheumatism, cold-dampness, is by Herba Senecionis Scandentis, ramulus mori, cassia twig, smelly goat, poplar After willow bark, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing adds water, first decocted with big fire to boiling, then keeps micro- with small fire Boiling state 40min, filtering, obtains decoction.
The composition of described treatment rheumatism, cold-dampness disease, its application method, be by pan-fried well-done decoction through natural cooling or Person adds cold decoction and blent, and regulation temperature is 38 DEG C, and allowing patient to be immersed in patient after 60min in decoction, bath can not dry, Decoction and sweat with allowing are spontaneously dried.
Embodiment 5
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 80g, ramulus mori 80g, cassia twig 220g, smelly goat 120g, willow skin 80g, mulberry skin 55g, yncaria stem with hooks 45g, notopterygium root 80g, levisticum 80g.
The preparation method of the sick composition of described treatment rheumatism, cold-dampness, is by Herba Senecionis Scandentis, ramulus mori, cassia twig, smelly goat, poplar After willow bark, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing adds water, first decocted with big fire to boiling, then keeps micro- with small fire Boiling state 35min, filtering, obtains decoction.
The composition of described treatment rheumatism, cold-dampness disease, its application method, be by pan-fried well-done decoction through natural cooling or Person adds cold decoction and blent, and regulation temperature is 38 DEG C, and allowing patient to be immersed in patient after 60min in decoction, bath can not dry, Decoction and sweat with allowing are spontaneously dried.
Embodiment 6
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 80g, ramulus mori 100g, cassia twig 180g, smelly goat 100g, willow skin 80g, mulberry skin 50g, yncaria stem with hooks 45g, notopterygium root 75g, levisticum 70g.
After raw material is cleaned, sealed and soaked with white wine, 15d is at least soaked in summer, 30d is at least soaked in the winter time, be made Steep in wine.
Embodiment 7
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 120g, ramulus mori 100g, cassia twig 220g, smelly goat 100g, willow skin 120g, mulberry skin 50g, yncaria stem with hooks 55g, notopterygium root 75g, levisticum 80g.
Raw material is weighed, cleaned, is crushed, 18~25% pregelatinized starch of total amount is added, then soaked with 75% ethanol Profit, by granulator granulation, is made particle, sieves, obtains pill.
Embodiment 8
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 80g, ramulus mori 80g, cassia twig 180g, smelly goat 120g, willow skin 120g, mulberry skin 55g, yncaria stem with hooks 45g, notopterygium root 70g, levisticum 70g.
After raw material is weighed, clean, crush, add water to cook into the medicinal extract that water content is 12~15%, add medicinal extract quality 18~25% amylum pregelatinisatum, then with 65% ethanol infiltrate, add total amount 0.5% magnesium stearate mix, pass through Tablet press machine is tabletted, obtains tablet.
Embodiment 9
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 120g, ramulus mori 120g, cassia twig 220g, smelly goat 80g, willow skin 80g, mulberry skin 45g, yncaria stem with hooks 55g, notopterygium root 80g, levisticum 80g.
Raw material is weighed, cleaned, is crushed, then with methylcellulose or alginates or polyvinyl alcohol or metagelatin system Standby capsulae vacuus is wrapped up, and is prepared into capsule.
Embodiment 10
It is a kind of to treat rheumatism, the composition of cold-dampness disease, including following raw material by weight:Herba Senecionis Scandentis 100g, ramulus mori 100g, cassia twig 200g, smelly goat 100g, willow skin 100g, mulberry skin 50g, yncaria stem with hooks 50g, notopterygium root 75g, levisticum 75g.
After raw material is weighed, clean, add water infusion, add the ethanol of 5 times of amounts of filtrate gross mass, reclaim after ethanol, adjust The sugar content for saving residual solution is 20~30%, and oral liquid is made in packaging.
Experimental example
1st, toxicity test:
1.1.1, medicine:Using any combination thing of embodiment 1~10.
1.1.2, subjects:The small white mouse 100 of selection health health, male and female half and half, 25~30g of body weight, Breeding observing 3d under artificial light 12h, ventilation condition good situations, is randomly divided into 2 groups, one of which is blank control examination group, Forbid within 4 hours feed after 12h and administration before administration, but can't help water.
1.2nd, method:After 3d, except blank group, another set small white mouse is gavaged dosage for 0.05ml/g, implementation Any combination thing of example 1~10, observes 7d.
1.3rd, result:Continuous Observation 7d, whole small white mouses are good for the spirit of living and whole small white mouses, appetite, secretion, exhaled Do not observe exception in terms of suction, eye, by experiment mice and control group mice after analysing, each histoorgan is without obvious sense Difference, cores, liver, spleen, lung, kidney and intestines make pathological section also without significantly different, increased dosage amount, same method gavages embodiment 1~10 any combination thing, whole mouse are still good for and lived, and are compared without exception with control group, illustrate that said composition is pacified to mouse Atoxic.
2nd, the rheumatism cold-dampness patient for randomly selecting identical sick age is some, is randomly divided into 10 groups, be respectively adopted embodiment 1~ 10 compositions prepared are treated, the applicant's tracking follow-up, absorbing state of the patient to medicine are counted, as a result such as the institute of table 1 Show:
Table 1
Explanation:The present invention is outer formulation, preferably dipping bath decoction, but on the basis of the formula of the present invention on also may be used Be made as steeping in wine, other formulations of pill, tablet, capsule or oral liquid, pass through 1 couple of one age patient of table and two ages From the point of view of the absorbing state of patient, the effect of the formulation of dipping bath decoction of the invention is substantially better than other formulations.
2nd, efficacy test example:The present invention takes safety, easy to operate, evident in efficacy, efficient high, and is clinical data institute Prove, the relevant clinical data of the present invention is as follows:
1st, Hu:39 years old, man was diagnosed as rheumatism cold-dampness disease through the traditional Chinese medical science in November, 2015, during which takes some analgesics Medicine is treated, and continue for 1 year, during which recurrent exerbation, after 1 course for the treatment of of top dipping bath, is thought that pain symptom mitigates, is continued Take pain after two courses for the treatment of to disappear, each course for the treatment of 7d.
2nd, Liu so-and-so:40 years old, man, in January, 2014 was diagnosed as rheumatism cold-dampness disease through the traditional Chinese medical science, using western medicine, continue for 8 Individual month, during which recurrent exerbation, after 2 courses for the treatment of of top dipping bath, thought that pain symptom mitigates, continues to take pain after three courses for the treatment of Sense disappears, each course for the treatment of 7d.
3rd, the Qin so-and-so:52 years old, female was diagnosed as rheumatism cold-dampness disease through the traditional Chinese medical science in March, 2015, using western medicine, continued 3 months, during which recurrent exerbation, after 1 course for the treatment of of top dipping bath, thought that pain symptom mitigates, continues to take and ache after 1 course for the treatment of Pain disappears, each course for the treatment of 7d.
4th, so-and-so is thanked:50 years old, female was diagnosed as rheumatism cold-dampness disease, in December, 2016 in October, 2014 through the traditional Chinese medical science Start, with pain symptom mitigation is felt after 1 course for the treatment of of top dipping bath, to continue to take pain after 2 courses for the treatment of and disappear, each course for the treatment of 7d。
So far, patient body is healthy always for the present inventor's follow-up, and the incidence of disease is persistently reduced, and the pain fallen ill every time is gradually Decline, wherein, improvement rate is more than 88%.

Claims (8)

1. a kind of treat rheumatism, the composition of cold-dampness disease, it is characterised in that including following raw material by weight:Herba Senecionis Scandentis 80~120, ramulus mori 80~120, cassia twig 180~220, smelly goat 80~120, willow skin 80~120, mulberry skin 45~55, yncaria stem with hooks 45~55, notopterygium root 70~80, levisticum 70~80.
2. as claimed in claim 1 treatment rheumatism, cold-dampness disease composition, it is characterised in that including it is following by weight Raw material:Herba Senecionis Scandentis 100, ramulus mori 100, cassia twig 200, smelly goat 100, willow skin 100, mulberry skin 50, yncaria stem with hooks 50, notopterygium root 75, solely Living 75.
3. treating rheumatism, the composition of cold-dampness disease as claimed in claim 1, it is characterised in that described composition, it is preferably External used medicine.
4. rheumatism, the composition of cold-dampness disease are treated as claimed in claim 1, it is characterised in that described composition, is dipping bath Decoction.
5. the preparation method of the sick composition for the treatment of rheumatism, cold-dampness as described in Claims 1 to 4, it is characterised in that be by nine li After light, ramulus mori, cassia twig, smelly goat, willow skin, mulberry skin, yncaria stem with hooks, notopterygium root, levisticum are weighed, mixing, add water, first decocted with big fire to After boiling, then with small fire holding 30~40min of slight boiling condition, filter, obtain decoction.
6. the composition for the treatment of rheumatism as described in Claims 1 to 4, cold-dampness disease, it is characterised in that its application method, be by Decoct well-done decoction to be blent through natural cooling or the cold decoction of addition, regulation temperature is 38~42 DEG C, allows patient to be immersed in Patient can not dry after 40~60min in decoction, bath, allow with decoction and sweat spontaneously dry.
7. treatment rheumatism, the composition of cold-dampness disease as described in Claims 1 to 4, it is characterised in that in use, to decoction When carrying out temperature adjustment, it is impossible to add hot water or cold water, to add cold decoction or medicine of a warm nature liquid carries out temperature adjustment.
8. rheumatism, the composition of cold-dampness disease are treated as claimed in claim 1 or 2, it is characterised in that described composition, also Can be prepared into oral formulations, including steep in wine, pill, tablet, capsule.
CN201710199854.0A 2017-03-29 2017-03-29 It is a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof Pending CN106937980A (en)

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CN201710199854.0A CN106937980A (en) 2017-03-29 2017-03-29 It is a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof

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CN106937980A true CN106937980A (en) 2017-07-11

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CN201710199854.0A Pending CN106937980A (en) 2017-03-29 2017-03-29 It is a kind of to treat rheumatism, composition of cold-dampness disease and preparation method thereof

Country Status (1)

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CN (1) CN106937980A (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘兰芳: "《名老中医临床用药心得荟萃》", 31 March 2008, 金盾出版社 *

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