CN106730041A - Neurosurgery post-operation anti-adhesion film and preparation method thereof - Google Patents
Neurosurgery post-operation anti-adhesion film and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
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Abstract
The invention discloses a kind of neurosurgery post-operation anti-adhesion film and preparation method thereof, the Antiadhesive film is prepared from by the raw material of following weight portion：PVC17~34 part, PU5~18 part, PA13~19 part, 7~11 parts of polyester thermoplastic elastomer, 24~38 parts of regenerated silk fibroin fiber, 0.8~1.6 part of methacrylate, 3~6 parts of butyl acrylate, 1~3 part of alkyl starches ester, 7~13 parts of core-shell acrylic elastic emulsion, 3~9 parts of lauryl alcohol sulfate of ammoniac, 2.1~8 parts of inorganic nano-particle, 0.1~0.2 part of vanillic aldehyde, 0.1~0.2 part of thymol.Compared with prior art, the present invention is preventing adhesion and promotes on CO2 laser weld effect more preferable, and carries bactericidal antiphlogistic function.
Description
Technical field
The present invention relates to field of medical materials, and in particular to a kind of neurosurgery post-operation anti-adhesion film and preparation method thereof.
Background technology
Adhesion is the anomaly sxtructure that connective fiber is combined together and is formed with adjacent tissue or organ, its size
Can be from the film of a piece of fiber to dense blood vessel scar.Post-operation adhesion is one of operation common complication.Root it is reported that
The abdominal cavity of 50-100% and operation on pelvis can cause different degrees of adhesion.The sequelae that postoperative tissue adhesion is brought is hand
Art position constant pain, loses partial function.
Disease of the neurosurgery mainly for the nervous system such as brain, spinal cord caused by wound.Neurosurgery
Adhesion afterwards also has adhesion organization or organ in addition to being related to the adhesion problems of general surgical operation influences asking for nervous system
Topic.For example, it is common treatment method that operative treatment waist pushes away disc herniation, a portion underwent operative reaches healing purpose.
But the still small leg outer side of patient with the presence of 10%~21% and dorsal portion numbness and uncomfortableness sense, nerve root surrounding tissue adhesion compression
It is its main cause.
Additionally, after neurosurgery, even if the peripheral nerve rupture wound of fresh cleaning, and using advanced micro- outer
Section's technology is modified, and can not possibly generally also be regenerated completely, and function also tends to recover completely.For example, should be micro-
It is clinically main method that suturing skill repairs peripheral nerve injury, but because inflammatory reaction etc. causes office after simple suture
Portion's cicatricial tissue hyperplasia adhesion directly affects refreshing modified effect.Nerve suture mouth goes out the increasing of cicatricial tissue after micro suture
The raw and local adhesion with surrounding tissue not only influences local microcirculation, and scar can hinder Regenerating Axons to distal end in early days
Extend, late period may pull pressuring nerve previous anastomotic again, cause neural micro- arrangement architecture disorderly, hinder the extensive of nervous function
It is multiple.
Although having some reports on Antiadhesive film at present, on these Antiadhesive films to neurosurgery operation rear defence
The effect of adhesion membrane rarely has report.Chinese patent application CN104258472A reports the preparation of neurosurgery post-operation anti-adhesion film
Method, the method generally describes the preparation method of neurosurgery post-operation anti-adhesion film.Chinese patent application CN105396180A
A kind of biodegradable plasticizer, medical anti-adhesive film and preparation method thereof are reported, but such medical anti-adhesive film is wide
It is general for preventing adhesion, without mention this Antiadhesive film for neurosurgery post-operation adhesion preventing effect.
Therefore, there is a need in the art for the Antiadhesive film for preventing neurosurgery post-operation adhesion with good result.
The content of the invention
To solve the above problems, the invention provides a kind of neurosurgery post-operation anti-adhesion film and preparation method thereof.
To achieve the above object, the technical scheme taken of the present invention is：
Neurosurgery post-operation anti-adhesion film, is prepared from by the raw material of following weight portion：
17~34 parts of PVC, 5~18 parts of PU, 13~19 parts of PA, 7~11 parts of polyester thermoplastic elastomer, regenerated silk
24~38 parts of azelon, 0.8~1.6 part of methacrylate, 3~6 parts of butyl acrylate, 1~3 part of alkyl starches ester, core
7~13 parts of shell acrylic elastic emulsion, 3~9 parts of lauryl alcohol sulfate of ammoniac, 2.1~8 parts of inorganic nano-particle, vanillic aldehyde 0.1~
0.2 part, 0.1~0.2 part of thymol.
Preferably, it is prepared from by the raw material of following weight portion：
17 parts of PVC, 5 parts of PU, 13 parts of PA, 7 parts of polyester thermoplastic elastomer, 24 parts of regenerated silk fibroin fiber, methyl
0.8 part of acrylate, 3 parts of butyl acrylate, 1 part of alkyl starches ester, 7 parts of core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac 3
Part, 2.1 parts of inorganic nano-particle, 0.1 part of vanillic aldehyde, 0.1 part of thymol.
Preferably, it is prepared from by the raw material of following weight portion：
25 parts of PVC, 16.5 parts of PU, 16 parts of PA, 9 parts of polyester thermoplastic elastomer, 31 parts of regenerated silk fibroin fiber,
1.2 parts of methacrylate, 4.5 parts of butyl acrylate, 2 parts of alkyl starches ester, 10 parts of core-shell acrylic elastic emulsion, lauryl alcohol
6 parts of sulfate of ammoniac, 5.05 parts of inorganic nano-particle, 0.15 part of vanillic aldehyde, 0.15 part of thymol.
Preferably, it is prepared from by the raw material of following weight portion：34 parts of PVC, 18 parts of PU, 19 parts of PA, polyester thermoplastic
11 parts of elastomer, 38 parts of regenerated silk fibroin fiber, 1.6 parts of methacrylate, 6 parts of butyl acrylate, alkyl starches ester 3
Part, 13 parts of core-shell acrylic elastic emulsion, 9 parts of lauryl alcohol sulfate of ammoniac, 8 parts of inorganic nano-particle, 0.2 part of vanillic aldehyde, thymol
0.2 part.
The preparation method of above-mentioned neurosurgery post-operation anti-adhesion film, comprises the following steps：
S1, the formula as described in claim any one of 1-4 weigh each component；
S2, the PVC that will be weighed, PU, PA, polyester thermoplastic elastomer, methacrylate, regenerated silk fibroin are fine
Dimension, butyl acrylate, alkyl starches ester, core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac, glycerine, inorganic nano-particle, perfume (or spice)
Oxalaldehyde, thymol are placed in high speed mixer and are well mixed, and obtain mixture；
S3, the mixture of gained is carried out electrostatic spinning, and it is special that the spinning of gained is woven into three-dimensional staggered network structure
The fibrous mat structure levied；
S4, the fibrous mat structure of gained is dried, obtains final product Antiadhesive film.
Preferably, the inorganic nano-particle is nano silicon.
Preferably, 10-20 kilovolts of the electrostatic spinning voltage, receives apart from 8-11cm.
Preferably, the diameter range of described regenerated silk fibroin fiber is 300nm~7 μm.
Compared with prior art, the present invention is preventing adhesion and promotes on CO2 laser weld effect more preferable, and carries sterilization and disappear
Scorching function.
Specific embodiment
In order that objects and advantages of the present invention become more apparent, the present invention is carried out further with reference to embodiments
Describe in detail.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to limit this hair
It is bright.
In following examples, the inorganic nano-particle for being used is nano silicon,
The diameter range of the regenerated silk fibroin fiber for being used is 300nm~7 μm, and other materials is commercially available.Implement
Example 1
S1, weigh 17 parts of PVC, 5 parts of PU, 13 parts of PA, 7 parts of polyester thermoplastic elastomer, regenerated silk fibroin fiber 24
Part, 0.8 part of methacrylate, 3 parts of butyl acrylate, 1 part of alkyl starches ester, 7 parts of core-shell acrylic elastic emulsion, lauryl alcohol
3 parts of sulfate of ammoniac, 2.1 parts of inorganic nano-particle, 0.1 part of vanillic aldehyde, 0.1 part of thymol；
S2, the PVC that will be weighed, PU, PA, polyester thermoplastic elastomer, methacrylate, regenerated silk fibroin are fine
Dimension, butyl acrylate, alkyl starches ester, core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac, glycerine, inorganic nano-particle, perfume (or spice)
Oxalaldehyde, thymol are placed in high speed mixer and are well mixed, and obtain mixture；
S3, the mixture of gained is carried out electrostatic spinning, and it is special that the spinning of gained is woven into three-dimensional staggered network structure
The fibrous mat structure levied；10-20 kilovolts of the electrostatic spinning voltage, receives apart from 8-11cm.
S4, the fibrous mat structure of gained is dried, obtains final product Antiadhesive film.
Embodiment 2
S1, to weigh 25 parts of PVC, 16.5 parts of PU, 16 parts of PA, 9 parts of polyester thermoplastic elastomer, regenerated silk fibroin fine
31 parts of dimension, 1.2 parts of methacrylate, 4.5 parts of butyl acrylate, 2 parts of alkyl starches ester, core-shell acrylic elastic emulsion 10
Part, 6 parts of lauryl alcohol sulfate of ammoniac, 5.05 parts of inorganic nano-particle, 0.15 part of vanillic aldehyde, 0.15 part of thymol；
S2, the PVC that will be weighed, PU, PA, polyester thermoplastic elastomer, methacrylate, regenerated silk fibroin are fine
Dimension, butyl acrylate, alkyl starches ester, core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac, glycerine, inorganic nano-particle, perfume (or spice)
Oxalaldehyde, thymol are placed in high speed mixer and are well mixed, and obtain mixture；
S3, the mixture of gained is carried out electrostatic spinning, and it is special that the spinning of gained is woven into three-dimensional staggered network structure
The fibrous mat structure levied；10-20 kilovolts of the electrostatic spinning voltage, receives apart from 8-11cm.
S4, the fibrous mat structure of gained is dried, obtains final product Antiadhesive film.
Embodiment 3
S1, weigh 34 parts of PVC, 18 parts of PU, 19 parts of PA, 11 parts of polyester thermoplastic elastomer, regenerated silk fibroin fiber
38 parts, 1.6 parts of methacrylate, 6 parts of butyl acrylate, 3 parts of alkyl starches ester, 13 parts of core-shell acrylic elastic emulsion, ten
9 parts of glycol sulfate of ammoniac, 8 parts of inorganic nano-particle, 0.2 part of vanillic aldehyde, 0.2 part of thymol；
S2, the PVC that will be weighed, PU, PA, polyester thermoplastic elastomer, methacrylate, regenerated silk fibroin are fine
Dimension, butyl acrylate, alkyl starches ester, core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac, glycerine, inorganic nano-particle, perfume (or spice)
Oxalaldehyde, thymol are placed in high speed mixer and are well mixed, and obtain mixture；
S3, the mixture of gained is carried out electrostatic spinning, and it is special that the spinning of gained is woven into three-dimensional staggered network structure
The fibrous mat structure levied；10-20 kilovolts of the electrostatic spinning voltage, receives apart from 8-11cm.
S4, the fibrous mat structure of gained is dried, obtains final product Antiadhesive film.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (8)
1. neurosurgery post-operation anti-adhesion film, it is characterised in that be prepared from by the raw material of following weight portion：
PVC17~34 part, PU5~18 part, PA13~19 part, 7~11 parts of polyester thermoplastic elastomer, regenerated silk fibroin fiber
24~38 parts, 0.8~1.6 part of methacrylate, 3~6 parts of butyl acrylate, 1~3 part of alkyl starches ester, core-shell acrylic
In 7~13 parts of elastic emulsion, 3~9 parts of lauryl alcohol sulfate of ammoniac, 2.1~8 parts of inorganic nano-particle, 0.1~0.2 part of vanillic aldehyde, hundred
0.1~0.2 part of phenol.
2. neurosurgery post-operation anti-adhesion film as claimed in claim 1, it is characterised in that prepared by the raw material of following weight portion
Form：
PVC17 parts, PU5 parts, PA13 parts, 7 parts of polyester thermoplastic elastomer, 24 parts of regenerated silk fibroin fiber, methacrylic acid
0.8 part of ester, 3 parts of butyl acrylate, 1 part of alkyl starches ester, 7 parts of core-shell acrylic elastic emulsion, 3 parts of lauryl alcohol sulfate of ammoniac, nothing
2.1 parts of machine nano-particle, 0.1 part of vanillic aldehyde, 0.1 part of thymol.
3. neurosurgery post-operation anti-adhesion film as claimed in claim 1, it is characterised in that prepared by the raw material of following weight portion
Form：
PVC25 parts, PU16.5 parts, PA16 parts, 9 parts of polyester thermoplastic elastomer, 31 parts of regenerated silk fibroin fiber, metering system
1.2 parts of acid esters, 4.5 parts of butyl acrylate, 2 parts of alkyl starches ester, 10 parts of core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac 6
Part, 5.05 parts of inorganic nano-particle, 0.15 part of vanillic aldehyde, 0.15 part of thymol.
4. neurosurgery post-operation anti-adhesion film as claimed in claim 1, it is characterised in that prepared by the raw material of following weight portion
Form：
PVC34 parts, PU18 parts, PA19 parts, 11 parts of polyester thermoplastic elastomer, 38 parts of regenerated silk fibroin fiber, metering system
1.6 parts of acid esters, 6 parts of butyl acrylate, 3 parts of alkyl starches ester, 13 parts of core-shell acrylic elastic emulsion, 9 parts of lauryl alcohol sulfate of ammoniac,
8 parts of inorganic nano-particle, 0.2 part of vanillic aldehyde, 0.2 part of thymol.
5. the preparation method of neurosurgery post-operation anti-adhesion film, it is characterised in that comprise the following steps：
S1, the formula as described in claim any one of 1-4 weigh each component；
S2, the PVC that will be weighed, PU, PA, polyester thermoplastic elastomer, methacrylate, regenerated silk fibroin fiber, third
Olefin(e) acid butyl ester, alkyl starches ester, core-shell acrylic elastic emulsion, lauryl alcohol sulfate of ammoniac, glycerine, inorganic nano-particle, vanillic aldehyde,
Thymol is placed in high speed mixer and is well mixed, and obtains mixture；
S3, the mixture of gained is carried out electrostatic spinning, and the spinning of gained is woven into three-dimensional staggered network structure feature
Fibrous mat structure；
S4, the fibrous mat structure of gained is dried, obtains final product Antiadhesive film.
6. the preparation method of neurosurgery post-operation anti-adhesion film as claimed in claim 5, it is characterised in that the inorganic nano
Particle is nano silicon.
7. the preparation method of neurosurgery post-operation anti-adhesion film as claimed in claim 5, it is characterised in that the electrostatic spinning
Voltage 10-20 kilovolts, receive apart from 8-11cm.
8. the preparation method of neurosurgery post-operation anti-adhesion film as claimed in claim 5, it is characterised in that described regenerated silk
The diameter range of fibroin fiber is 300nm~7 μm.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611094316.7A CN106730041A (en) | 2016-12-02 | 2016-12-02 | Neurosurgery post-operation anti-adhesion film and preparation method thereof |
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| CN201611094316.7A CN106730041A (en) | 2016-12-02 | 2016-12-02 | Neurosurgery post-operation anti-adhesion film and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279902A (en) * | 2019-06-13 | 2019-09-27 | 四川大学华西医院 | A kind of neurosurgery post-operation anti-adhesion film and preparation method thereof |
| CN112773946A (en) * | 2021-02-24 | 2021-05-11 | 西安交通大学医学院第一附属医院 | Neurosurgery postoperative anti-adhesion membrane and preparation method thereof |
| CN115105646A (en) * | 2022-08-03 | 2022-09-27 | 西安交通大学医学院第一附属医院 | Neurosurgery postoperative anti-adhesion membrane and preparation method thereof |
| CN117582560A (en) * | 2023-10-09 | 2024-02-23 | 常州市智态生创科技有限公司 | Repairing film for preventing intrauterine adhesion and preparation method and application thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1739491A (en) * | 2005-09-15 | 2006-03-01 | 同济大学 | A kind of nanometer fiber slow-releasing system and its production and application |
| CN103469351A (en) * | 2013-07-18 | 2013-12-25 | 嘉兴学院 | Preparation method of vitamin C-loaded silk fibroin/hyaluronic acid composite nanofibers |
| CN104258472A (en) * | 2014-09-18 | 2015-01-07 | 郭玉臣 | Preparation method of anti-adhesive membrane used after neurosurgical operations |
| CN104356536A (en) * | 2014-10-24 | 2015-02-18 | 苏州蔻美新材料有限公司 | Medical antibacterial hose and preparation method thereof |
| CN105148366A (en) * | 2015-08-15 | 2015-12-16 | 内蒙古医科大学附属医院 | Breathing tube for paediatrics |
| CN105233384A (en) * | 2015-09-19 | 2016-01-13 | 陕西省人民医院 | Trachea cannula capable of monitoring air bag pressure automatically |
| CN105597161A (en) * | 2015-12-23 | 2016-05-25 | 新乡医学院第一附属医院 | Biodegradable intravascular stent with composite coating |
-
2016
- 2016-12-02 CN CN201611094316.7A patent/CN106730041A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1739491A (en) * | 2005-09-15 | 2006-03-01 | 同济大学 | A kind of nanometer fiber slow-releasing system and its production and application |
| CN103469351A (en) * | 2013-07-18 | 2013-12-25 | 嘉兴学院 | Preparation method of vitamin C-loaded silk fibroin/hyaluronic acid composite nanofibers |
| CN104258472A (en) * | 2014-09-18 | 2015-01-07 | 郭玉臣 | Preparation method of anti-adhesive membrane used after neurosurgical operations |
| CN104356536A (en) * | 2014-10-24 | 2015-02-18 | 苏州蔻美新材料有限公司 | Medical antibacterial hose and preparation method thereof |
| CN105148366A (en) * | 2015-08-15 | 2015-12-16 | 内蒙古医科大学附属医院 | Breathing tube for paediatrics |
| CN105233384A (en) * | 2015-09-19 | 2016-01-13 | 陕西省人民医院 | Trachea cannula capable of monitoring air bag pressure automatically |
| CN105597161A (en) * | 2015-12-23 | 2016-05-25 | 新乡医学院第一附属医院 | Biodegradable intravascular stent with composite coating |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279902A (en) * | 2019-06-13 | 2019-09-27 | 四川大学华西医院 | A kind of neurosurgery post-operation anti-adhesion film and preparation method thereof |
| CN112773946A (en) * | 2021-02-24 | 2021-05-11 | 西安交通大学医学院第一附属医院 | Neurosurgery postoperative anti-adhesion membrane and preparation method thereof |
| CN115105646A (en) * | 2022-08-03 | 2022-09-27 | 西安交通大学医学院第一附属医院 | Neurosurgery postoperative anti-adhesion membrane and preparation method thereof |
| CN117582560A (en) * | 2023-10-09 | 2024-02-23 | 常州市智态生创科技有限公司 | Repairing film for preventing intrauterine adhesion and preparation method and application thereof |
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Application publication date: 20170531 |