CN106722898A - A kind of Fructus Corni tonifies the liver and kidney lozenge and its production method - Google Patents
A kind of Fructus Corni tonifies the liver and kidney lozenge and its production method Download PDFInfo
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- CN106722898A CN106722898A CN201510820355.XA CN201510820355A CN106722898A CN 106722898 A CN106722898 A CN 106722898A CN 201510820355 A CN201510820355 A CN 201510820355A CN 106722898 A CN106722898 A CN 106722898A
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- 210000003734 kidney Anatomy 0.000 title claims abstract description 23
- 210000004185 liver Anatomy 0.000 title claims abstract description 23
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 239000003826 tablet Substances 0.000 claims abstract description 32
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 19
- 229920002472 Starch Polymers 0.000 claims abstract description 19
- 229940084030 carboxymethylcellulose calcium Drugs 0.000 claims abstract description 19
- 239000008103 glucose Substances 0.000 claims abstract description 19
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- 240000006995 Abutilon theophrasti Species 0.000 claims abstract description 14
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- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 14
- 238000001035 drying Methods 0.000 claims abstract description 13
- 230000036541 health Effects 0.000 claims abstract description 8
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- 239000003814 drug Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 7
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A kind of Fructus Corni tonifies the liver and kidney lozenge and its production method.By Fructus Corni, corydalis tuber, Ligusticum wallichii, purslane, piper wallichii, Chinese mahonia leaf, Galanga Galangal Seed, chingma abutilon seed, carboxymethylcellulose calcium,
Water soluble starch,
Glucose
Constituted Deng raw material, finished product is made by sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept；By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.The present invention
Have
Health care, tonify the liver and kidney, pure natural, pollution-free, no side effectses, the advantages of conveniently take and nourish the body.
Description
Technical field：
The present invention relates to field of food health care, and in particular to a kind of Fructus Corni tonifies the liver and kidney lozenge and its production method.
Background technology
Buccal tablet refers to the compressed tablets for being contained in slow mechanism dissolved in oral cavity, and lozenge will have tempting color from inside to outside, so that the mouthfeel that user has had.Therefore, the figuration composition in lozenge, such as sugar, pigment additive often " a presumptuous guest usurps the role of the host " so that some by mistake lozenge is regarded as " sugar ".
At present, most of lozenge of in the market is all medicine, and most of medicines for being to treat Throat diseases, and narrow application range, therapeutic effect is general.And it is few using the utilization rate for being processed into health products containing chip technology, it is few to body-care effect, it is impossible to meet the market demand.
The content of the invention：
It is an object of the invention to provide one kind collection tonify the liver and kidney, it is pure natural, pollution-free,
No side effectses are conveniently taken and are nourished the body in one
Fructus Corni tonify the liver and kidney lozenge and production method.
The object of the present invention is achieved like this.It is that the raw material matched somebody with somebody by following weight is made,
Fructus Corni
15-30
Part, corydalis tuber
10-20
Part, Ligusticum wallichii
5-15
Part, purslane
3-15
Part, piper wallichii
3-15
Part, Chinese mahonia leaf
3-10
Part, Galanga Galangal Seed
4-12
Part, chingma abutilon seed
6-9
Part, carboxymethylcellulose calcium
7-10
Part, water soluble starch
4-8
Part, glucose
10-15
Part.
Preparing the Fructus Corni of the present invention lozenge preferred weight ratio range that tonifies the liver and kidney is,
Fructus Corni
15-25
Part, corydalis tuber
10-15
Part, Ligusticum wallichii
5-12
Part, purslane
3-10
Part, piper wallichii
3-10
Part, Chinese mahonia leaf
3-8
Part, Galanga Galangal Seed
4-10
Part, chingma abutilon seed
6-8
Part, carboxymethylcellulose calcium
7-9
Part, water soluble starch
4-7
Part, glucose
10-14
Part.
Preparing the Fructus Corni of the present invention lozenge best weight ratio scope that tonifies the liver and kidney is,
Fructus Corni
20
Part, corydalis tuber
12
Part, Ligusticum wallichii
10
Part, purslane
8
Part, piper wallichii
8
Part, Chinese mahonia leaf
5
Part, Galanga Galangal Seed
8
Part, chingma abutilon seed
7
Part, carboxymethylcellulose calcium
8
Part, water soluble starch
6
Part, glucose
12
Part.
Above-mentioned each component is made into Fructus Corni of the present invention to tonify the liver and kidney the production method of lozenge, technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A
, sorting, by raw material weight proportioning of soup processed, select meet the Fructus Corni of national health and quality standard, corydalis tuber, Ligusticum wallichii, purslane, piper wallichii, Chinese mahonia leaf, Galanga Galangal Seed, chingma abutilon seed, carboxymethylcellulose calcium,
Water soluble starch,
Glucose feed is standby；
B
, drying, except carboxymethylcellulose calcium,
Water soluble starch,
Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists
80-100
DEG C, the time
45
Minute, raw material moisture is evaporated to water content
18%
, compressing tablet；
C
, decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device
2
It is secondary, add for the first time
7
Times water is decocted
1.5
Hour, second frame
5
Times water is decocted
1
Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution；
D
, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor；
E
, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F
, compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G
, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
With lozenge be combined the traditional Chinese medicine ingredients for having good tonic effect to human body by the present invention, there is more preferable assimilation effect compared to existing lozenge, it is convenient for people to usually take, conditioning health, increase metabolism balance in vivo, regulation human body homeostasis is softer, and lifting constitution is gentler, effective for a long time can increase human body power and work endurance.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept；By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.
In inventive formulation, Fructus Corni tonifies the liver and kidney, puckery smart hidroschesis, controls and has a dizzy spell, deaf, and spontaneous perspiration, soreness and weakness of waist and knees, impotence sends essence, frequent micturition；Corydalis tuber is invigorated blood circulation, sharp gas, analgesic, for chest side of body, epigastric pain, closed dysmenorrhea, postpartum stasis, tumbling and swelling
；
Ligusticum wallichii blood-activating and qi-promoting, wind-expelling pain-stopping, for irregular menstruation, closed dysmenorrhea, abdominal mass stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism；Purslane is clearing heat and detoxicating, cooling blood and hemostasis；For toxic-heat and blood stasis, carbuncle swells furunculosis, eczema, erysipelas, snake bite and insect sting is had blood in stool, hemorrhoid blood, metrostaxis；Piper wallichii is pungent, temperature, Return liver, the spleen channel, wind-damp dispelling, relaxing muscles and tendons network, strong waist and knee, except numbness pain, for wind-cold-dampness arthralgia, arthralgia and myalgia, waist-leg weakness, cough and asthma, kidney deficiency cough, impotence；Chinese mahonia leaf heat-clearing qi-restoratives, it is relieving cough and reducing sputum, tuberculosis hemoptysis are controlled, osteopyrexia and fever, dizziness and tinnitus, waist soreness is vexed, hot eyes；Galanga Galangal Seed middle benefit gas eliminating dampness；It is amusing and helps digestion；Main coldness and pain in the epigastrium；Dyspeptic abdominal distention, vomiting is had loose bowels；Dysphagia and regurgitation；
Chingma abutilon seed promoting diuresis for stranguria；Laxation defaecation；Lower breast；Main gonorrhoea；Oedema；Suffer from constipation；Newborn sweat is not all right
。
The present invention is summarized and perfect in taking and clinical verification by many cases patient, constantly, and recipe ratio is more complete, determined curative effect, deaf to having a dizzy spell
Deng master
Disease
Card：Degree difference is served
Tonify the liver and kidney, puckery smart hidroschesis
Effect,
Have
Health care, tonify the liver and kidney, pure natural, pollution-free, no side effectses the advantages of.
The present invention through two groups of clinical verifications, for treatment group take lozenge of the present invention, take once a day by one of which, and 7 days is a course for the treatment of, and " nourishing liver and kidney ball " is taken in another group of control,
Take once a day, be within 7 days a course for the treatment of, every group selection outpatient 200, wherein man 100, female 100, measure the big age 78
It is year, minimum
Age 26
Year,
Clinical manifestation is deaf to have a dizzy spell, spontaneous perspiration, soreness and weakness of waist and knees, frequent micturition
, toxic-heat and blood stasis, carbuncle swells furunculosis, eczema, erysipelas, snake bite and insect sting
, table one is to take the contrasting data after a course for the treatment of：
Table
1
Front and rear two groups of courses for the treatment of are taken to compare
(
Unit
:
People
)
There were significant differences for treatment group and control group, it will thus be seen that present invention application clinically has significant curative effect.
Technological advantage of the invention is：1st, raw material and scientific formulation are selected, production technology is advanced, its product produces taste well, convenient storage；2nd, without harmful components such as preservatives in product, nourishing and nutrition of the raw material to human body are kept, is easily absorbed by the body；3rd, raw material sources are extensive, plus process line is short, the manufacture of product easy processing.
Specific embodiment
With reference to specific embodiment, the present invention is further illustrated
Embodiment 1：It is deaf suitable for having a dizzy spell, spontaneous perspiration
Crowd
The Fructus Corni of the present invention lozenge that tonifies the liver and kidney is prepared to be made up of following component raw material（Consumption is weight portion）,
Fructus Corni
15-30
Part, corydalis tuber
10-20
Part, Ligusticum wallichii
5-15
Part, purslane
3-15
Part, piper wallichii
3-15
Part, Chinese mahonia leaf
3-10
Part, Galanga Galangal Seed
4-12
Part, chingma abutilon seed
6-9
Part, carboxymethylcellulose calcium
7-10
Part, water soluble starch
4-8
Part, glucose
10-15
Part.
Embodiment 2：Suitable for soreness and weakness of waist and knees, frequent micturition
, toxic-heat and blood stasis, carbuncle swells furunculosis
Crowd
Preparing the Fructus Corni of the present invention lozenge preferred weight ratio range that tonifies the liver and kidney is：
Fructus Corni
15-25
Part, corydalis tuber
10-15
Part, Ligusticum wallichii
5-12
Part, purslane
3-10
Part, piper wallichii
3-10
Part, Chinese mahonia leaf
3-8
Part, Galanga Galangal Seed
4-10
Part, chingma abutilon seed
6-8
Part, carboxymethylcellulose calcium
7-9
Part, water soluble starch
4-7
Part, glucose
10-14
Part.
Embodiment
3
：It is applied to
Eczema, erysipelas, snake bite and insect sting
Crowd
Preparing the Fructus Corni of the present invention lozenge best weight ratio scope that tonifies the liver and kidney is, 20 parts of Fructus Corni, 12 parts of corydalis tuber, 10 parts of Ligusticum wallichii, 8 parts of purslane, 8 parts of piper wallichii, 5 parts of Chinese mahonia leaf, 8 parts of Galanga Galangal Seed, 7 parts of chingma abutilon seed, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
Embodiment 4
Above-mentioned each component is made into Fructus Corni of the present invention to tonify the liver and kidney the production method of lozenge, technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A
, sorting, by raw material weight proportioning of soup processed, select meet the Fructus Corni of national health and quality standard, corydalis tuber, Ligusticum wallichii, purslane, piper wallichii, Chinese mahonia leaf, Galanga Galangal Seed, chingma abutilon seed, carboxymethylcellulose calcium,
Water soluble starch,
Glucose feed is standby；
B
, drying, except carboxymethylcellulose calcium,
Water soluble starch,
Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists
80-100
DEG C, the time
45
Minute, raw material moisture is evaporated to water content
18%
, compressing tablet；
C
, decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device
2
It is secondary, add for the first time
7
Times water is decocted
1.5
Hour, second frame
5
Times water is decocted
1
Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution；
D
, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor；
E
, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F
, compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G
, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
Embodiment
2
If adding appropriate disintegrant such as in the prescription of lozenge
CMS-Na
Improve and contain tablet stability, or add the mediation mouthfeel such as cane sugar powder, mannitol, sorbierite, various sweeteners, essence.
Claims (4)
1. a kind of Fructus Corni tonifies the liver and kidney lozenge, it is characterised in that：It is that the raw material matched by following weight is made, Fructus Corni 15-30 parts, corydalis tuber 10-20 parts, Ligusticum wallichii 5-15 parts, purslane 3-15 parts, piper wallichii 3-15 parts, Chinese mahonia leaf 3-10 parts, Galanga Galangal Seed 4-12 parts, chingma abutilon seed 6-9 parts, carboxymethylcellulose calcium 7-10 parts, water soluble starch 4-8 parts, glucose 10-15 parts.
2. a kind of Fructus Corni according to claim 1 tonifies the liver and kidney lozenge, it is characterised in that：The weight proportion of wherein various raw materials is, Fructus Corni 15-25 parts, corydalis tuber 10-15 parts, Ligusticum wallichii 5-12 parts, purslane 3-10 parts, piper wallichii 3-10 parts, Chinese mahonia leaf 3-8 parts, Galanga Galangal Seed 4-10 parts, chingma abutilon seed 6-8 parts, carboxymethylcellulose calcium 7-9 parts, water soluble starch 4-7 parts, glucose 10-14 parts.
3. a kind of Fructus Corni according to claim 1 tonifies the liver and kidney lozenge, it is characterised in that：The weight proportion of wherein various raw materials is, 20 parts of Fructus Corni, 12 parts of corydalis tuber, 10 parts of Ligusticum wallichii, 8 parts of purslane, 8 parts of piper wallichii, 5 parts of Chinese mahonia leaf, 8 parts of Galanga Galangal Seed, 7 parts of chingma abutilon seed, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
4. the Fructus Corni according to claim 1-3 tonifies the liver and kidney the production method of lozenge, it is characterised in that：Technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A, sorting, by raw material weight proportioning of soup processed, select that to meet the Fructus Corni of national health and quality standard, corydalis tuber, Ligusticum wallichii, purslane, piper wallichii, Chinese mahonia leaf, Galanga Galangal Seed, chingma abutilon seed, carboxymethylcellulose calcium, water soluble starch, glucose feed standby；
B, drying, in addition to carboxymethylcellulose calcium, water soluble starch, glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control 45 minutes time, makes raw material moisture be evaporated to water content 18%, compressing tablet at 80-100 DEG C；
C, decoction, by above-mentioned ratio of weight and number, decocted 2 times during the raw material addition after drying is put into decocting device, for the first time plus 7 times of waters are decocted 1.5 hours, second frame, 5 times of waters are decocted 1 hour, and filtrate is extracted in filtering respectively, filtrate will be merged twice, the secondary filter dregs of a decoction and impurity, are obtained extract solution；
D, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor；
E, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F, compressing tablet, the impurity that above-mentioned mixed powder is removed the generation in production process, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510820355.XA CN106722898A (en) | 2015-11-24 | 2015-11-24 | A kind of Fructus Corni tonifies the liver and kidney lozenge and its production method |
Applications Claiming Priority (1)
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| CN106722901A (en) * | 2015-11-24 | 2017-05-31 | 哈尔滨墨医生物技术有限公司 | A kind of Radix Codonopsis invigorating spleen and reinforcing stomach lozenge and its production method |
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