CN106618804A - Bone induction differentiated metal bone trabecula knee joint prosthesis and preparation method thereof - Google Patents
Bone induction differentiated metal bone trabecula knee joint prosthesis and preparation method thereof Download PDFInfo
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- CN106618804A CN106618804A CN201611232181.6A CN201611232181A CN106618804A CN 106618804 A CN106618804 A CN 106618804A CN 201611232181 A CN201611232181 A CN 201611232181A CN 106618804 A CN106618804 A CN 106618804A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3859—Femoral components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/389—Tibial components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30011—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in porosity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30028—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in tissue ingrowth capacity, e.g. made from both ingrowth-promoting and ingrowth-preventing parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
- A61F2002/30943—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using mathematical models
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
- A61F2002/30955—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using finite-element analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
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- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Physics & Mathematics (AREA)
- Geometry (AREA)
- Manufacturing & Machinery (AREA)
- Prostheses (AREA)
Abstract
The invention belongs to the field of medical apparatus, and particularly relates to a bone induction differentiated metal bone trabecula knee joint prosthesis and a preparation method thereof under the precision control using incremental manufacturing technology. The prosthesis comprises a femoral condyle prosthesis, a tibial plateau prosthesis, a tibial plateau pad prosthesis and a patellar prosthesis. Osseointegration interfaces of the femoral condyle prosthesis, tibial plateau prosthesis and patellar prosthesis is in the structure of the bone induction differentiated metal bone trabecula. The preparation method comprises the steps of determining the gradient structure of stress and strain in knee prosthesis, determining the parameters of the porous structure of trabecular bone, establishing a three-dimensional model of the porous structure, conducting slicing and stratification treatment of the three-dimensional model, and conducting electron beam incremental manufacturing of the knee joint prosthesis metal bone trabecula, cooling to obtain the final finished product. The bone induction differentiated metal bone trabecula knee joint prosthesis and the preparation method thereof for the first time achieve the balance between the stress and bone induction performance for stress regions of different osseointegration interfaces of bone in knee joint, satisfy the differentiation requirement of bone induction, provide a preparation method of mass production, and effectively reduces manufacturing cost.
Description
Technical field
The present invention relates to medical instruments field, more particularly to a kind of metal bone trabecula knee-joint prosthesis of self-bone grafting differentiation
And preparation method thereof.
Background technology
In orthopaedics artificial prosthesis implant surgery, effective Integrated implant between prosthese and bone how is realized, whether prosthese possesses
Be conducive to the interface of later stage Bone Ingrowth, the focus that always clinician is concerned about very much.
Trabecular bone structure is a kind of space network in bone, is interconnected between hole.It is that one kind has tight hole
The complex organization of gap structure.
The stress of bone：In normal human's bone Gegenbaur's cell and osteoclast by stress come the growth or absorption to bone
Regulated and controled.When the stress of bone is less than 2MPa, bone tissue absorbs；When the stress of bone is about in 20-60MPa, bone tissue
Grow；And when the stress of bone is approximately higher than 60MPa, bone tissue is damaged.So, if implantation prosthese cannot meet respectively
The different stress demand of individual contact surface, will occur some stress areas because stress shielding occurs the feelings of bone information or bone injury
Condition.
Bone is different according to stress, and trabecular bone structure is also different.Under the premise of stress identical, diamond structure reaches 80% hole
During gap rate, with natural trabecular bone structure closest to and anti-pressure ability most match.
At present, in global artificial knee joint prosthesis, do not occur according to knee joint difference stress area configuration different metal bone
The prosthetic designs of trabecularism, fail to solve asking for prosthese and bone interface good integration after the knee joint that clinician is concerned about
Topic.
Metal bone trabecula Product checking means at this stage are to damage detection, and Non-Destructive Testing is in the bar for not damaging test specimen
Under part, with either physically or chemically as means, by advanced technology and equipment equipment, the knot of inside and surface to test specimen
The method that structure, property, state are checked and tested.Its feature has non-destructive, mutual compatibility, dynamic, stringency etc..Solution
Having determined must damage at this stage the problem of detection, and for mass production reliable guarantee is provided.
The content of the invention
The technical problem to be solved is to overcome the deficiencies in the prior art, there is provided a kind of present invention is wanted
The technical problem of solution is to provide a kind of metal bone trabecula knee-joint prosthesis structure of self-bone grafting differentiation, realizes that knee joint bone is whole
Close balance of the interface in stress and self-bone grafting aspect of performance, and then realize the same of Integrated implant on same prosthetic component Integrated implant interface
Step property.
The present invention is to be achieved by the following technical programs：
A kind of preparation method of the metal bone trabecula knee-joint prosthesis of self-bone grafting differentiation, comprises the following steps：
(1) knee joint metal bone trabecula interface carries out gradient subregion according to stress and strain；
Human femur under loading, shin bone, kneecap and knee-joint prosthesis model are set up using computer technology, using finite element analysis
Method applies 3 to 5 times of human body weight load in femoral head pivot, confirms the stress and strain at Integrated implant interface, goes forward side by side
Row gradient subregion；
When the strain of bone is less than 2MPa less than 100 microstrains, stress, bone tissue absorbs, and Integrated implant interface is water chestnut
Shape loose structure；
When bone strain in 1500-3000 microstrains, stress in 20-60MPa when, bone tissue grows, Integrated implant circle
Face is spirality loose structure；
When the strain of bone is higher than 60MPa higher than 3000 microstrains, stress, bone tissue is damaged, and Integrated implant interface is
Rounded porous structure；
(2) according to the characteristic at Integrated implant interface, Parametric designing is carried out to knee joint metal bone trabecula loose structure：Work as bone
When stress is less than 2MPa, between 700-900 μm, porosity is about 90% in aperture；When bone stress is in 20-60MPa, aperture exists
Between 500-700 μm, porosity is about 80%；When bone stress is higher than 60MPa, between 300-500 μm, porosity is about in aperture
For 70%；
(3) according to the Mathematical Modeling of different loose structures, its threedimensional model is built respectively in CAD software so as to reach
Use requirement；
(4) file that threedimensional model is converted to STL forms is preserved, then imports the file into electron beam equipment and be
Slicing delamination process is carried out in system control software, minimum single layer thicknesses are 50 μm.
(5) model after slicing delamination is processed is manufactured.In the fabrication process, using Arcam companies of Sweden
Q10Plus electron beam melting technical equipment, the equipment has on-line monitoring function, records the sensor registration in print procedure,
Including vacuum, beam power, electrion number of times, powder amount etc. is taken, all the sensors registration is equipped with upper limit alarm numerical value
With lower limit warning numerical value, and print procedure is successively detected using machine vision method；The concrete ginseng of Q10Plus equipment
Number is：Maximum electron beam power 3kW, compressed air maximum supply gas pressure is 9 bars, and environment temperature is controlled at 20 to 25 degrees Celsius,
Humidity is below 40%；
(6) print after terminating, transfer the on-line monitoring report of electron beam equipment generation, check whether existing defects.Treat zero
Part after natural cooling, is separated around metal trabecular bone structure and intrapore unfused powder in a device using compressed air
Grain.After taking out part, lossless quick detection is carried out to metal trabecular bone structure parameter, using quality-volume direct computing methodTo detect porosity, so as to verify whether each parameter of product reaches design requirement, finally clean, go out
Bacterium, packaging.In quality-volume direct computing method formula, M is sample mass (g), and V is volume of sample (cm3), ρSFor porous body
Density (the g/cm of correspondence compact solid material3)；
(7) product is finally cleaned in 100,000 grades of clean rooms, the product after cleaning-drying adopts 3 layers of PAPE/CPT
7 layers of composite film packaging bag carry out vacuum forming packaging, additional 1 layer of packing box and 1 layer of plastic uptake film external packing, make after irradiation sterilization
With.
The knee-joint prosthesis model is posterior cruciate ligament of knee not conservative knee-joint prosthesis, and it is provided with the rear friendship for cooperating
Fork ligament not conservative tibial plateau prosthese and posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis, the posterior cruciate ligament of knee does not retain
Type tibial plateau prosthese lower surface side is provided with two tibial plateau hexagon connection columns, and opposite side is provided with tibial plateau cylinder
Shape connects column；
Gradient in step (1) distinguish obtained by result be：
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative tibial plateau prosthese,
Posterior cruciate ligament of knee not conservative tibial plateau lower surface outside 1/2 Facing material bone strain less than 100 it is micro- should
Become, stress is less than 2MPa；
Posterior cruciate ligament of knee not conservative tibial plateau lower surface inner side 1/2 Facing material bone strain it is micro- in 1500-3000
Strain, stress are in 20-60MPa；
Tibial plateau hexagon connects should uprising for the bone of the Facing material of column and tibial plateau cylinder connection column
In 3000 microstrains, stress higher than 60MPa；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative lateral femoral condyle prosthesis,
Posterior cruciate ligament of knee not the bone of conservative lateral femoral condyle prosthesis postartis Facing material strain be less than 100 microstrains, stress
Less than 2MPa；
The strain of the posterior cruciate ligament of knee not bone of the intercondylar material of conservative lateral femoral condyle prosthesis is higher than higher than 3000 microstrains, stress
60MPa；
The strain of posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis preartis and remaining Integrated implant interface material bone is in 1500-
3000 microstrains, stress are in 20-60MPa.
The knee-joint prosthesis model is posterior cruciate ligament of knee conservative knee-joint prosthesis, and it is provided with the rear intersection for cooperating
Ligament conservative tibial plateau and posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis, under posterior cruciate ligament of knee conservative tibial plateau prosthese
Side is provided with tibial plateau connecting cylinder, and connecting cylinder is symmetrically arranged on two with tibial plateau triangle wing plate；
The posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis both sides are symmetrical arranged condyle of femur hexagon connection column；
Gradient in step (1) distinguish obtained by result be：
In the Integrated implant interface of posterior cruciate ligament of knee conservative tibial plateau prosthese,
The strain of the bone of posterior cruciate ligament of knee conservative tibial plateau body lower surface material is low less than 100 microstrains, stress
In 2MPa；
Posterior cruciate ligament of knee conservative cylinder tibial plateau connection column material bone strain 1500-3000 it is micro- should
Change, stress are in 20-60MPa；
The strain of the bone of two tibial plateau dalta wing sheet material matter is higher than 60MPa higher than 3000 microstrains, stress；
In the Integrated implant interface of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis,
The strain of the bone of the postartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is less than less than 100 microstrains, stress
2MPa；
The strain of the bone of the preartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is in 1500-3000 microstrains, stress
In 20-60MPa；
The condyle of femur hexagon connection column and the bone of remaining Integrated implant interface material of posterior cruciate ligament of knee conservative condyle of femur
Strain higher than 3000 microstrains, stress be higher than 60MPa.
The knee-joint prosthesis model is provided with patellar prosthesis, and patellar prosthesis include patellar prosthesis main body and located at patellar prosthesis
Kneecap connecting pole on the outside of main body；
In the Integrated implant face of patellar prosthesis,
The strain of the bone of patellar prosthesis body outer surface material is in 1500-3000 microstrains, stress in 20-60MPa；
The strain of the bone of kneecap connection outer surface of column material is higher than 60MPa higher than 3000 microstrains, stress.
A kind of preparation method system of the metal bone trabecula knee-joint prosthesis of the self-bone grafting differentiation described in application claim 1
The metal bone trabecula knee-joint prosthesis of standby self-bone grafting differentiation, including tibial plateau prosthese, on tibial plateau prosthese
Tibial plateau pad prosthese, lateral femoral condyle prosthesis on tibial plateau pad prosthese and false located at tibial plateau pad prosthese and condyle of femur
The patellar prosthesis of body front end, the Integrated implant interface of the tibial plateau prosthese, lateral femoral condyle prosthesis and patellar prosthesis is poor for self-bone grafting
Alienation metal trabecular bone structure.
The knee-joint prosthesis model is posterior cruciate ligament of knee not conservative knee-joint prosthesis, and it is provided with the rear friendship for cooperating
Fork ligament not conservative tibial plateau prosthese and posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis, the posterior cruciate ligament of knee does not retain
Type tibial plateau prosthese lower surface side is provided with two tibial plateau hexagon connection columns, and opposite side is provided with tibial plateau cylinder
Shape connects column；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative tibial plateau prosthese,
1/2 Facing material of conservative tibial plateau lower surface outside is not that rhombus cellular structure metals bone is little to posterior cruciate ligament of knee
Beam；
Posterior cruciate ligament of knee not conservative tibial plateau lower surface inner side 1/2 Facing material for spirality loose structure metal
Bone trabecula；
It is rounded porous knot that tibial plateau hexagon connects column and the Facing material of tibial plateau cylinder connection column
The metal bone trabecula of structure；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative lateral femoral condyle prosthesis,
Conservative lateral femoral condyle prosthesis postartis Facing material is not rhombus cellular structure metals bone trabecula to posterior cruciate ligament of knee；
Posterior cruciate ligament of knee not the intercondylar material of conservative lateral femoral condyle prosthesis for rounded porous structure metal bone trabecula；
Conservative lateral femoral condyle prosthesis preartis and remaining Integrated implant interface material are not spirality loose structure to posterior cruciate ligament of knee
Metal bone trabecula.
The knee-joint prosthesis model is posterior cruciate ligament of knee conservative knee-joint prosthesis, and it is provided with the rear intersection for cooperating
Ligament conservative tibial plateau and posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis, under posterior cruciate ligament of knee conservative tibial plateau prosthese
Side is provided with tibial plateau connecting cylinder, and connecting cylinder is symmetrically arranged on two with tibial plateau triangle wing plate；
The posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis both sides are symmetrical arranged condyle of femur hexagon connection column；
In the Integrated implant interface of posterior cruciate ligament of knee conservative tibial plateau prosthese,
Posterior cruciate ligament of knee conservative tibial plateau body lower surface material is rhombus cellular structure metals bone trabecula；
Posterior cruciate ligament of knee conservative cylinder tibial plateau connection column material is little for the metal bone of spirality loose structure
Beam
Two tibial plateau dalta wing sheet material matter are the metal bone trabecula of rounded porous structure；
In the Integrated implant interface of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis,
The postartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is rhombus cellular structure metals bone trabecula；
The preartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is the metal bone trabecula of spirality loose structure；
The condyle of femur hexagon connection column and remaining Integrated implant interface material of posterior cruciate ligament of knee conservative condyle of femur is circle
The metal bone trabecula of shape loose structure.
The knee-joint prosthesis model is provided with patellar prosthesis, and patellar prosthesis include patellar prosthesis main body and located at patellar prosthesis
Kneecap connecting pole on the outside of main body；
In the Integrated implant face of patellar prosthesis,
Patellar prosthesis body outer surface material is the metal bone trabecula of spirality loose structure；
Kneecap connection outer surface of column material is the metal bone trabecula of rounded porous structure.
The invention has the beneficial effects as follows：
Present invention achieves for knee joint difference Integrated implant interface stress area in stress and self-bone grafting aspect of performance
Balance, meets the differentiated demand of self-bone grafting.
Description of the drawings
Fig. 1 is the main structure diagram of the present invention.
Fig. 2 is the rounded porous structural metal trabecular bone structure schematic diagram of the present invention.
Fig. 3 is the rhombus cellular structure metals trabecular bone structure schematic diagram of the present invention.
Fig. 4 is the spirality cellular structure metals trabecular bone structure schematic diagram of the present invention.
Fig. 5 is posterior cruciate ligament of knee of the invention not conservative tibial plateau borrowed structure schematic diagram.
Fig. 6 is posterior cruciate ligament of knee of the invention not conservative lateral femoral condyle prosthesis structural representation.
Fig. 7 is the posterior cruciate ligament of knee conservative tibial plateau borrowed structure schematic diagram of the present invention.
Fig. 8 is the posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis structural representation of the present invention.
Fig. 9 is the patellar prosthesis main structure diagram of the present invention.
Figure 10 is the schematic flow sheet of the preparation method of the present invention.
In figure：1. tibial plateau prosthese, 2. tibial plateau pad prosthese, 3. lateral femoral condyle prosthesis, 4. patellar prosthesis, 5. circular more
Pore structure, 6. rhombus loose structure, 7. spirality loose structure, 8. posterior cruciate ligament of knee not conservative tibial plateau prosthese, 9. after
Ligamentaum cruciatum not conservative lateral femoral condyle prosthesis, 10. tibial plateau hexagon connection column, 11. tibial plateaus cylinder connection is vertical
Post, 12. posterior cruciate ligament of knee conservative tibial plateaus, 13. posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis, the connection of 14. tibial plateaus
Cylinder, 15. tibial plateau triangle wing plates, 16. condyle of femur hexagons connection column, 17. patellar prosthesis main bodys, the connection of 18. kneecaps
Post.
Specific embodiment
In order that those skilled in the art more fully understand technical scheme, below in conjunction with the accompanying drawings and most
The present invention is described in further detail for good embodiment.
The preparation method of the metal bone trabecula knee-joint prosthesis of the self-bone grafting differentiation of the present invention, comprises the following steps：
(1) knee joint metal bone trabecula interface carries out gradient subregion according to stress and strain；
Human femur under loading, shin bone, kneecap and knee-joint prosthesis model are set up using computer technology, using finite element analysis
Method applies 3 to 5 times of human body weight load in femoral head pivot, confirms the stress and strain at Integrated implant interface, goes forward side by side
Row gradient subregion；
When the strain of bone is less than 2MPa less than 100 microstrains, stress, bone tissue absorbs, and Integrated implant interface is water chestnut
Shape loose structure；
When bone strain in 1500-3000 microstrains, stress in 20-60MPa when, bone tissue grows, Integrated implant circle
Face is spirality loose structure；
When the strain of bone is higher than 60MPa higher than 3000 microstrains, stress, bone tissue is damaged, and Integrated implant interface is
Rounded porous structure；
(2) according to the characteristic at Integrated implant interface, Parametric designing is carried out to knee joint metal bone trabecula loose structure：Work as bone
When stress is less than 2MPa, between 700-900 μm, porosity is about 90% in aperture；When bone stress is in 20-60MPa, aperture exists
Between 500-700 μm, porosity is about 80%；When bone stress is higher than 60MPa, between 300-500 μm, porosity is about in aperture
For 70%；
(3) according to the Mathematical Modeling of different loose structures, its threedimensional model is built respectively in CAD software so as to reach
Use requirement；
(4) file that threedimensional model is converted to STL forms is preserved, then imports the file into electron beam equipment and be
Slicing delamination process is carried out in system control software, minimum single layer thicknesses are 50 μm.
(5) model after slicing delamination is processed is manufactured.In the fabrication process, using Arcam companies of Sweden
Q10Plus electron beam melting technical equipment, the equipment has on-line monitoring function, records the sensor registration in print procedure,
Including vacuum, beam power, electrion number of times, powder amount etc. is taken, all the sensors registration is equipped with upper limit alarm numerical value
With lower limit warning numerical value, and print procedure is successively detected using machine vision method；The concrete ginseng of Q10Plus equipment
Number is：Maximum electron beam power 3kW, compressed air maximum supply gas pressure is 9 bars, and environment temperature is controlled at 20 to 25 degrees Celsius,
Humidity is below 40%；
(6) print after terminating, transfer the on-line monitoring report of electron beam equipment generation, check whether existing defects.Treat zero
Part after natural cooling, is separated around metal trabecular bone structure and intrapore unfused powder in a device using compressed air
Grain.After taking out part, lossless quick detection is carried out to metal trabecular bone structure parameter, using quality-volume direct computing methodTo detect porosity, so as to verify whether each parameter of product reaches design requirement, finally clean, go out
Bacterium, packaging.In quality-volume direct computing method formula, M is sample mass (g), and V is volume of sample (cm3), ρSFor porous body
Density (the g/cm of correspondence compact solid material3)；
The use nondestructive determination of innovation, substitute it is traditional damage detection method, under conditions of test specimen is not damaged, with physics
Or chemical method is means, by advanced technology and equipment equipment, structure, property, the state of inside and surface to test specimen
Checked and tested.There is non-destructive, mutual compatibility, dynamic, stringency.
(7) product is finally cleaned in 100,000 grades of clean rooms, the product after cleaning-drying adopts 3 layers of PAPE/CPT
7 layers of composite film packaging bag carry out vacuum forming packaging, additional 1 layer of packing box and 1 layer of plastic uptake film external packing, make after irradiation sterilization
With.
Knee-joint prosthesis include tibial plateau prosthese 1, and the tibial plateau pad prosthese 2 on tibial plateau prosthese is located at
Lateral femoral condyle prosthesis 3 and the patellar prosthesis 4 located at tibial plateau pad prosthese Yu lateral femoral condyle prosthesis front end on tibial plateau pad prosthese；
Knee joint prepared by a kind of metal bone trabecula knee-joint prosthesis method of the self-bone grafting differentiation in the present invention
The Integrated implant interface of the tibial plateau prosthese, lateral femoral condyle prosthesis and patellar prosthesis of prosthese is self-bone grafting differentiation metal bone trabecula knot
Structure, i.e., according to the characteristic at Integrated implant interface, can more preferably metal bone using the less position matching osteoinductive of stress and strain
The principle of trabecularism, presses gradient subregion and matches the metal bone trabecula of different structure on Integrated implant interface.
Such as Fig. 5, Fig. 6, using metal bone trabecula knee-joint prosthesis and preparation method thereof the institute of self-bone grafting differentiation of the present invention
A kind of embodiment of knee-joint prosthesis of preparation is：
Knee-joint prosthesis model is posterior cruciate ligament of knee not conservative knee-joint prosthesis, and it is tough that it is provided with the rear intersection for cooperating
Band not conservative tibial plateau prosthese 8 and posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis 9, posterior cruciate ligament of knee not conservative shin bone
Platform prosthese lower surface side is provided with two tibial plateau hexagon connection columns 10, and opposite side is provided with tibial plateau cylinder even
Connect column 11；
Gradient in step (1) distinguish obtained by result be：
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative tibial plateau prosthese,
Posterior cruciate ligament of knee not conservative tibial plateau lower surface outside 1/2 Facing material bone strain less than 100 it is micro- should
Become, stress is less than 2MPa, therefore its material is rhombus cellular structure metals bone trabecula；
Posterior cruciate ligament of knee not conservative tibial plateau lower surface inner side 1/2 Facing material bone strain it is micro- in 1500-3000
Strain, stress are in 20-60MPa, therefore its material is the metal bone trabecula of spirality loose structure；
Tibial plateau hexagon connects should uprising for the bone of the Facing material of column and tibial plateau cylinder connection column
In 3000 microstrains, stress higher than 60MPa, therefore its material is rounded porous structural metal bone trabecula；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative lateral femoral condyle prosthesis,
Posterior cruciate ligament of knee not the bone of conservative lateral femoral condyle prosthesis postartis Facing material strain be less than 100 microstrains, stress
Less than 2MPa, therefore its material is rhombus cellular structure metals bone trabecula；
The strain of the posterior cruciate ligament of knee not bone of the intercondylar material of conservative lateral femoral condyle prosthesis is higher than higher than 3000 microstrains, stress
60MPa, therefore its material is the metal bone trabecula of rounded porous structure；
The strain of posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis preartis and remaining Integrated implant interface material bone is in 1500-
3000 microstrains, stress are in 20-60MPa, therefore its material is the metal bone trabecula of spirality loose structure.
Such as Fig. 7, Fig. 8, the metal bone trabecula knee-joint prosthesis of application self-bone grafting differentiation of the present invention and preparation method thereof institute
Preparation knee-joint prosthesis another kind embodiment be：
The knee-joint prosthesis model is posterior cruciate ligament of knee conservative knee-joint prosthesis, and it is provided with the rear intersection for cooperating
Ligament conservative tibial plateau 12 and posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis 13, posterior cruciate ligament of knee conservative tibial plateau is false
Body downside is provided with tibial plateau connecting cylinder 14, and connecting cylinder is symmetrically arranged on two with tibial plateau triangle wing plate 15；
The posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis both sides are symmetrical arranged condyle of femur hexagon connection column 16；
Gradient in step (1) distinguish obtained by result be：
In the Integrated implant interface of posterior cruciate ligament of knee conservative tibial plateau prosthese,
The strain of the bone of posterior cruciate ligament of knee conservative tibial plateau body lower surface material is low less than 100 microstrains, stress
In 2MPa；Therefore its material is rhombus cellular structure metals bone trabecula；
Posterior cruciate ligament of knee conservative cylinder tibial plateau connection column material bone strain 1500-3000 it is micro- should
Change, stress are in 20-60MPa, therefore its material is the metal bone trabecula of spirality loose structure.
The strain of the bone of two tibial plateau dalta wing sheet material matter is higher than 60MPa higher than 3000 microstrains, stress, therefore its
Material is the metal bone trabecula of rounded porous structure.
In the Integrated implant interface of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis,
The strain of the bone of the postartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is less than less than 100 microstrains, stress
2MPa, therefore its material is rhombus cellular structure metals bone trabecula；
The strain of the bone of the preartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is in 1500-3000 microstrains, stress
In 20-60MPa, therefore its material is the metal bone trabecula of spirality loose structure；
The condyle of femur hexagon connection column and the bone of remaining Integrated implant interface material of posterior cruciate ligament of knee conservative condyle of femur
Strain higher than 3000 microstrains, stress be higher than 60MPa.Therefore its material is the metal bone trabecula of rounded porous structure.
Such as Fig. 9, the metal bone trabecula knee-joint prosthesis and preparation method thereof using self-bone grafting differentiation of the present invention are prepared
Knee-joint prosthesis, wherein patellar prosthesis include patellar prosthesis main body 17, and on the outside of patellar prosthesis main body kneecap connection
Post 18；
In the Integrated implant face of patellar prosthesis,
The strain of the bone of patellar prosthesis body outer surface material in 1500-3000 microstrains, stress in 20-60MPa, therefore
Its material is the metal bone trabecula of spirality loose structure；
The strain of the bone of kneecap connection outer surface of column material is higher than 60MPa higher than 3000 microstrains, stress, therefore its material
For the metal bone trabecula of rounded porous structure.
Such as Fig. 2, Fig. 3 and Fig. 4, the bone trabecular three-dimensional porous structure of metal is mainly including rounded porous structure 5, rhombus porous
Structure 6, spirality loose structure 7；Self-bone grafting differentiation metal trabecular bone structure in the present invention is according to knee joint stress area
Difference three kinds of loose structures are respectively attached to the zones of different on knee-joint prosthesis surface.
In the present invention make bone trabecula raw material metal dust be Ti6Al4V, the one kind in Al, C, Fe, H, N, O, Ti, V
Or combination.
Present invention achieves for knee joint difference Integrated implant interface stress area in stress and self-bone grafting aspect of performance
Balance, meets the differentiated demand of self-bone grafting.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (8)
1. the preparation method of the metal bone trabecula knee-joint prosthesis of a kind of self-bone grafting differentiation, it is characterised in that including following step
Suddenly：
(1) knee joint metal bone trabecula interface carries out gradient subregion according to stress and strain；
Human femur under loading, shin bone, kneecap and knee-joint prosthesis model are set up using computer technology, using the method for finite element analysis
Apply 3 to 5 times of human body weight load in femoral head pivot, confirm the stress and strain at Integrated implant interface, and carry out ladder
Degree subregion；
When the strain of bone is less than 2MPa less than 100 microstrains, stress, bone tissue absorbs, and Integrated implant interface is that rhombus is more
Pore structure；
When bone strain in 1000-3000 microstrains, stress in 20-60MPa when, bone tissue grows, and Integrated implant interface is
Spirality loose structure；
When the strain of bone is higher than 60MPa higher than 3000 microstrains, stress, bone tissue is damaged, and Integrated implant interface is circle
Loose structure；
(2) according to the characteristic at Integrated implant interface, Parametric designing is carried out to knee joint metal bone trabecula loose structure：Work as bone stress
During less than 2MPa, between 700-900 μm, porosity is about 90% in aperture；When bone stress is in 20-60MPa, aperture is in 500-
Between 700 μm, porosity is about 80%；When bone stress is higher than 60MPa, between 300-500 μm, porosity is about in aperture
70%；
(3) according to the Mathematical Modeling of different loose structures, its threedimensional model is built respectively in CAD software so as to reach and use
Require；
(4) file that threedimensional model is converted to STL forms is preserved, is then imported the file into the system control of electron beam equipment
Slicing delamination process is carried out in software processed, minimum single layer thicknesses are 50 μm.
(5) model after slicing delamination is processed is manufactured.In the fabrication process, using the Q10 of Arcam companies of Sweden
Plus electron beam melting technical equipment, the equipment has on-line monitoring function, records the sensor registration in print procedure, including
Vacuum, beam power, electrion number of times, take powder amount etc., all the sensors registration be equipped with upper limit alarm numerical value and under
Limit warning numerical value, and print procedure is successively detected using machine vision method；The design parameter of Q10 Plus equipment
For：Maximum electron beam power 3kW, compressed air maximum supply gas pressure is 9 bars, and environment temperature is controlled at 20 to 25 degrees Celsius, wet
Degree is below 40%；
(6) print after terminating, transfer the on-line monitoring report of electron beam equipment generation, check whether existing defects.Treat that part exists
In equipment after natural cooling, separated around metal trabecular bone structure using compressed air and intrapore unfused powder particle.
After taking out part, lossless quick detection is carried out to metal trabecular bone structure parameter, using quality-volume direct computing methodTo detect porosity, so as to verify whether each parameter of product reaches design requirement, finally clean, go out
Bacterium, packaging.In quality-volume direct computing method formula, M is sample mass (g), and V is volume of sample (cm3), ρSFor porous body
Density (the g/cm of correspondence compact solid material3)；
(7) product is finally cleaned in 100,000 grades of clean rooms, the product after cleaning-drying adopts 3 layers of 7 layers of PAPE/CPT
Composite film packaging bag carries out vacuum forming packaging, additional 1 layer of packing box and 1 layer of plastic uptake film external packing, uses after irradiation sterilization.
2. metal bone trabecula knee-joint prosthesis of a kind of self-bone grafting differentiation according to claim 1 and preparation method thereof,
Characterized in that,
The knee-joint prosthesis model is posterior cruciate ligament of knee not conservative knee-joint prosthesis, and it is tough that it is provided with the rear intersection for cooperating
Band not conservative tibial plateau prosthese and posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis, the posterior cruciate ligament of knee not conservative shin
Bone platform prosthese lower surface side is provided with two tibial plateau hexagon connection columns, and opposite side is provided with tibial plateau cylinder even
Connect column；
Gradient in step (1) distinguish obtained by result be：
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative tibial plateau prosthese,
Posterior cruciate ligament of knee not conservative tibial plateau lower surface outside 1/2 Facing material bone strain less than 100 microstrains, should
Power is less than 2MPa；
Posterior cruciate ligament of knee not conservative tibial plateau lower surface inner side 1/2 Facing material bone strain 1500-3000 microstrains,
Stress is 20-60MPa；
Tibial plateau hexagon connects the strain of the bone of the Facing material of column and tibial plateau cylinder connection column
3000 microstrains, stress are higher than 60MPa；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative lateral femoral condyle prosthesis,
The strain of the posterior cruciate ligament of knee not bone of conservative lateral femoral condyle prosthesis postartis Facing material is less than less than 100 microstrains, stress
2MPa；
The strain of the posterior cruciate ligament of knee not bone of the intercondylar material of conservative lateral femoral condyle prosthesis is higher than higher than 3000 microstrains, stress
60MPa；
The strain of posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis preartis and remaining Integrated implant interface material bone is micro- in 1500-3000
Strain, stress are in 20-60MPa.
3. metal bone trabecula knee-joint prosthesis of a kind of self-bone grafting differentiation according to claim 1 and preparation method thereof,
Characterized in that,
The knee-joint prosthesis model is posterior cruciate ligament of knee conservative knee-joint prosthesis, and it is provided with the posterior cruciate ligament of knee for cooperating
Conservative tibial plateau and posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis, posterior cruciate ligament of knee conservative tibial plateau prosthese downside sets
There is tibial plateau connecting cylinder, connecting cylinder is symmetrically arranged on two with tibial plateau triangle wing plate；
The posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis both sides are symmetrical arranged condyle of femur hexagon connection column；
Gradient in step (1) distinguish obtained by result be：
In the Integrated implant interface of posterior cruciate ligament of knee conservative tibial plateau prosthese,
The strain of the bone of posterior cruciate ligament of knee conservative tibial plateau body lower surface material is less than less than 100 microstrains, stress
2MPa；
Posterior cruciate ligament of knee conservative cylinder tibial plateau connection column material bone strain 1500-3000 microstrains, should
Power is in 20-60MPa；
The strain of the bone of two tibial plateau dalta wing sheet material matter is higher than 60MPa higher than 3000 microstrains, stress；
In the Integrated implant interface of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis,
The strain of the bone of the postartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is less than 2MPa less than 100 microstrains, stress；
The strain of the bone of the preartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is in 1500-3000 microstrains, stress in 20-
60MPa；
Posterior cruciate ligament of knee conservative condyle of femur condyle of femur hexagon connection column and remaining Integrated implant interface material bone should
It is higher than 60MPa to become higher than 3000 microstrains, stress.
4. metal bone trabecula knee-joint prosthesis of a kind of self-bone grafting differentiation according to claim 1 and preparation method thereof,
Characterized in that,
The knee-joint prosthesis model is provided with patellar prosthesis, and patellar prosthesis include patellar prosthesis main body and located at patellar prosthesis main body
The kneecap connecting pole in outside；
In the Integrated implant face of patellar prosthesis,
The strain of the bone of patellar prosthesis body outer surface material is in 1500-3000 microstrains, stress in 20-60MPa；
The strain of the bone of kneecap connection outer surface of column material is higher than 60MPa higher than 3000 microstrains, stress.
5. prepared by a kind of preparation method of the metal bone trabecula knee-joint prosthesis of the self-bone grafting differentiation described in application claim 1
Self-bone grafting differentiation metal bone trabecula knee-joint prosthesis, including tibial plateau prosthese, the shin on tibial plateau prosthese
Bone platform pad prosthese, lateral femoral condyle prosthesis on tibial plateau pad prosthese and located at tibial plateau pad prosthese and lateral femoral condyle prosthesis
The patellar prosthesis of front end, it is characterised in that the Integrated implant interface of the tibial plateau prosthese, lateral femoral condyle prosthesis and patellar prosthesis is
Self-bone grafting differentiation metal trabecular bone structure.
6. the metal bone trabecula knee joint of the self-bone grafting differentiation described in a kind of application claim 1 as claimed in claim 5
The metal bone trabecula knee-joint prosthesis of self-bone grafting differentiation prepared by the preparation method of prosthese, it is characterised in that the knee joint
Prosthese model is posterior cruciate ligament of knee not conservative knee-joint prosthesis, and it is provided with the posterior cruciate ligament of knee for cooperating not conservative shin bone
Platform prosthese and posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis, the posterior cruciate ligament of knee not conservative tibial plateau prosthese following table
Face side is provided with two tibial plateau hexagon connection columns, and opposite side is provided with tibial plateau cylinder connection column；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative tibial plateau prosthese,
1/2 Facing material of conservative tibial plateau lower surface outside is not rhombus cellular structure metals bone trabecula to posterior cruciate ligament of knee；
Conservative tibial plateau lower surface 1/2 Facing material of inner side is not little for the metal bone of spirality loose structure for posterior cruciate ligament of knee
Beam；
It is rounded porous structure that tibial plateau hexagon connects column and the Facing material of tibial plateau cylinder connection column
Metal bone trabecula；
Posterior cruciate ligament of knee is in the Integrated implant interface of conservative lateral femoral condyle prosthesis,
Conservative lateral femoral condyle prosthesis postartis Facing material is not rhombus cellular structure metals bone trabecula to posterior cruciate ligament of knee；
Posterior cruciate ligament of knee not the intercondylar material of conservative lateral femoral condyle prosthesis for rounded porous structure metal bone trabecula；
Posterior cruciate ligament of knee not conservative lateral femoral condyle prosthesis preartis and remaining Integrated implant interface material for spirality loose structure gold
Category bone trabecula.
7. the metal bone trabecula knee joint of the self-bone grafting differentiation described in a kind of application claim 1 as claimed in claim 5
The metal bone trabecula knee-joint prosthesis of self-bone grafting differentiation prepared by the preparation method of prosthese, it is characterised in that the knee joint
Prosthese model is posterior cruciate ligament of knee conservative knee-joint prosthesis, and it is provided with the posterior cruciate ligament of knee conservative tibial plateau for cooperating
And posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis, posterior cruciate ligament of knee conservative tibial plateau prosthese downside is provided with tibial plateau connection
Cylinder, connecting cylinder is symmetrically arranged on two with tibial plateau triangle wing plate；
The posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis both sides are symmetrical arranged condyle of femur hexagon connection column；
In the Integrated implant interface of posterior cruciate ligament of knee conservative tibial plateau prosthese,
Posterior cruciate ligament of knee conservative tibial plateau body lower surface material is rhombus cellular structure metals bone trabecula；
Posterior cruciate ligament of knee conservative cylinder tibial plateau connection column material is the metal bone trabecula of spirality loose structure
Two tibial plateau dalta wing sheet material matter are the metal bone trabecula of rounded porous structure；
In the Integrated implant interface of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis,
The postartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is rhombus cellular structure metals bone trabecula；
The preartis material of posterior cruciate ligament of knee conservative lateral femoral condyle prosthesis is the metal bone trabecula of spirality loose structure；
The condyle of femur hexagon connection column and remaining Integrated implant interface material of posterior cruciate ligament of knee conservative condyle of femur is circular many
The metal bone trabecula of pore structure.
8. the metal bone trabecula knee joint of the self-bone grafting differentiation described in a kind of application claim 1 as claimed in claim 5
The metal bone trabecula knee-joint prosthesis of self-bone grafting differentiation prepared by the preparation method of prosthese, it is characterised in that the knee joint
Prosthese model is provided with patellar prosthesis, and patellar prosthesis include patellar prosthesis main body and the connection of the kneecap on the outside of patellar prosthesis main body
Post；
In the Integrated implant face of patellar prosthesis,
Patellar prosthesis body outer surface material is the metal bone trabecula of spirality loose structure；
Kneecap connection outer surface of column material is the metal bone trabecula of rounded porous structure.
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080234833A1 (en) * | 2004-03-23 | 2008-09-25 | B.I. Tec Ltd | Method of Designing and Manufacturing Artificial Joint Stem with Use of Composite Material |
| US20100131245A1 (en) * | 2006-09-20 | 2010-05-27 | Smith & Nephew, Inc. | Variable stiffness stem for prosthetic implants |
| CN103584930A (en) * | 2013-10-23 | 2014-02-19 | 华南理工大学 | Reverse design and production method of individual total knee prosthetic implant |
| CN104190930A (en) * | 2014-08-29 | 2014-12-10 | 中国科学院重庆绿色智能技术研究院 | Laser additive manufacturing method for homogeneous functionally graded material and structure |
| CN104706446A (en) * | 2015-03-24 | 2015-06-17 | 李鹏 | Bionic bone trabecula cervical vertebral fusion cage and manufacturing method thereof |
| CN104887351A (en) * | 2015-05-31 | 2015-09-09 | 西安赛隆金属材料有限责任公司 | High-strength small-bore metal bone trabecula and preparation method of same |
| US20160022370A1 (en) * | 2013-03-15 | 2016-01-28 | Otismed Corporation | Generation of a Mating Surface Model for Patient Specific Cutting Guide Based on Anatomical Model Segmentation |
| CN105748177A (en) * | 2016-04-20 | 2016-07-13 | 华南理工大学 | Personalized spine implantation prosthesis with bionic micropores and manufacturing method thereof |
| CN105912803A (en) * | 2016-04-28 | 2016-08-31 | 华南理工大学 | Additive manufacturing-based product lightweight design method |
-
2016
- 2016-12-28 CN CN201611232181.6A patent/CN106618804B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080234833A1 (en) * | 2004-03-23 | 2008-09-25 | B.I. Tec Ltd | Method of Designing and Manufacturing Artificial Joint Stem with Use of Composite Material |
| US20100131245A1 (en) * | 2006-09-20 | 2010-05-27 | Smith & Nephew, Inc. | Variable stiffness stem for prosthetic implants |
| US20160022370A1 (en) * | 2013-03-15 | 2016-01-28 | Otismed Corporation | Generation of a Mating Surface Model for Patient Specific Cutting Guide Based on Anatomical Model Segmentation |
| CN103584930A (en) * | 2013-10-23 | 2014-02-19 | 华南理工大学 | Reverse design and production method of individual total knee prosthetic implant |
| CN104190930A (en) * | 2014-08-29 | 2014-12-10 | 中国科学院重庆绿色智能技术研究院 | Laser additive manufacturing method for homogeneous functionally graded material and structure |
| CN104706446A (en) * | 2015-03-24 | 2015-06-17 | 李鹏 | Bionic bone trabecula cervical vertebral fusion cage and manufacturing method thereof |
| CN104887351A (en) * | 2015-05-31 | 2015-09-09 | 西安赛隆金属材料有限责任公司 | High-strength small-bore metal bone trabecula and preparation method of same |
| CN105748177A (en) * | 2016-04-20 | 2016-07-13 | 华南理工大学 | Personalized spine implantation prosthesis with bionic micropores and manufacturing method thereof |
| CN105912803A (en) * | 2016-04-28 | 2016-08-31 | 华南理工大学 | Additive manufacturing-based product lightweight design method |
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