CN106581126A - Plant calcium preparation and preparing method thereof - Google Patents
Plant calcium preparation and preparing method thereof Download PDFInfo
- Publication number
- CN106581126A CN106581126A CN201611100787.4A CN201611100787A CN106581126A CN 106581126 A CN106581126 A CN 106581126A CN 201611100787 A CN201611100787 A CN 201611100787A CN 106581126 A CN106581126 A CN 106581126A
- Authority
- CN
- China
- Prior art keywords
- powder
- calcium
- parts
- inulin
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/733—Fructosans, e.g. inulin
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Abstract
The invention provides a plant calcium preparation and a preparing method thereof. The plant calcium preparation is prepared from, by weight, 40-80 parts of aizoon stonecrop herb powder, 10-30 parts of powder of cucumber seeds and 10-25 parts of inulin. The plant calcium preparations is formed by mixing the components to be uniform and smashing the mixture. The components of the plant calcium preparation are derived from food, and thus the plant calcium preparation is safe and free of toxic and side effects; the components reasonably match and synergically interact with one another; as a plant calcium preparation which has high content of calcium, the plant calcium preparation is easy to absorb and has no harm to the kidneys; meanwhile, the aizoon stonecrop herb has a large amount of rich plant general flavones, and thus the aizoon stonecrop herb has great auxiliary treatment functions on high blood pressure, cardiovascular and cerebrovascular diseases and the like through scientific eating and using.
Description
Technical field
The present invention relates to a kind of nutritional preparation and preparation method thereof, especially a kind of plant calcium preparation and preparation method thereof.
Background technology
Calcium supplementing product at this stage mainly has the two big class calcium-supplementing preparations such as inorganic and organic calcium salt, biological bone calcium class, its
In inorganic, organic calcium salt include Calcium Carbonate, calcium gluconate, calcium lactate etc., this kind of calcium preparation has that water solublity is not high, inhales
Yield is relatively low, and have certain irritating shortcoming to the intestines and stomach, in Equations of The Second Kind calcium supplementing product, has natural biological bone calcium (fishbone
Calcium, Os Bovis grunniens calcium etc.) and chelating calcium preparation (calcium amino acid chelate), although the species of the calcium supplementing product on market is various, carbon
Sour calcium remains calcium-supplementing preparation most widely used at present.
Inorganic, organic calcium salt include the calcium preparation such as Calcium Carbonate, calcium gluconate, calcium lactate exist water solublity it is not high,
Absorbance is relatively low, and have certain irritating shortcoming to the intestines and stomach.The preparation technology of calcium amino acid chelate include aminoacid dissolving,
Plus the operation such as slaine, chelatropic reaction, organic solvent deposit product, separation, reaction condition is wayward, complex process, yield
It is low.For Calcium in Plants is with respect to animal calcium and minerals calcium, Calcium in Plants easily absorbs, and is not impairment of the kidney, preferably calcareous as calcium replenishing
Source, is the optimal choosing of middle-aged and elderly people, infant, pregnant women, climacteric women.Contained calcium is the day that human body easily absorbs
So plant water-soluble organic calcium, is presented with crudeness, is most healthy, most safe, maximally effective food of replenishing the calcium.
Herba Sedi Aizoon be Crassulaceae Sedum herbaceos perennial, also known as Herba Sedi Aizoon, Herba Sedi Aizoon, HUOXUEDAN, JIUMINGCAO,
Herba Galii Teneri, blood mountain grass, see blood dissipate, Sedum aizoon L. etc..It is a kind of high calcium vegetable of medicine-food two-purpose.The dish is China Technological research personnel
Recently collect from remote, thickly forested mountains in the wild edible vegetable for coming, middle select what excellent improvement was cultivated with newest technological meanses are excellent
A kind of new product vegetable.
Herba Sedi Aizoon (Herba Sedi Aizoon) is a kind of preferable health-care vegetable, rich in proteins, carbohydrate, fat, thick fine
Dimension, carotene, vitamin B1, vitamin B2, vitamin C, calcium, phosphorus, ferrum, sitosterol, alkaloid, sedoheptose, flavonoid, have
The multiple components such as machine acid；Therefore the dish has lowering blood pressure and blood fat, blood circulation promoting and blood stasis dispelling, the strong gas mind calming suppressing the hyperactive liver of the beneficial heart and clearing away heat and cooling blood
Function, and can the liver protecting.Also there is the functions such as calmness, coronary artery dilator, removing toxic substances.Can be used to prevent and treat the heart disease (rhythm of the heart
Not normal, paroxysmal tachycardia, rheumatic heart disease etc.), hysteria, insomnia, hypertension, hyperlipidemia, arteriosclerosis, apoplexy, blood
Platelet reduction property purpura, gingival hemorrhage, digestive system hemorrhage, traumatic injury viral influenza and hepatitis etc. more than 10 plant disease aobvious
Curative effect is write, and without toxicity, side effect.
At present, Herba Sedi Aizoon (Herba Sedi Aizoon) mainly carries out marketing in the form of vegetable, in order to improve Herba Sedi Aizoon
Using effect, preferably service for mankind's health industry, fill up the market vacancy of market plant calcium product, research and develop with Herba Sedi Aizoon
There is wide market prospect Deng the plant calcium preparation for raw material.
The content of the invention
The technical problem to be solved is to provide a kind of plant calcium preparation.
Another technical problem to be solved by this invention is the preparation method for providing above-mentioned plant calcium preparation.
To solve above-mentioned technical problem, the technical scheme is that：
A kind of plant calcium preparation, is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, the nourishing heart vegetable powder based on its parts by weight
40-80 parts, cucumber seed powder 10-30 parts, inulin 10-25 parts.
Above-mentioned plant calcium preparation can add one or more adjuvant and/or additive, such as water according to dosage form needs
Fruit powder, Semen phaseoli radiati powder, maltodextrin, isomaltulose, phosphopeptide caseinate, vitamin and mineral, xanthan gum, arabic gum,
Sucralose, edible essence etc., the various dosage forms being mixed for example, can be made into granule, powder, tablet, capsule, micro-
Granule, slow releasing tablet.Preferred dosage form is powder and granule.
Preferably, above-mentioned plant calcium preparation, 65 parts of nourishing heart vegetable powder, 20 parts of cucumber seed powder, inulin 20 based on its parts by weight
Part.
Preferably, above-mentioned plant calcium preparation, the nourishing heart vegetable powder are obtained by following methods：
(1) fresh and tender, ripe Herba Sedi Aizoon is selected to carry out roguing, cleaning；
(2) the Herba Sedi Aizoon fresh leaf after roguing, cleaning is completed in roller fixation machine, wherein temperature is 90-110 DEG C, when
Between be 2-5min；
(3) it is beaten in the Herba Sedi Aizoon input beater after completing；
(4) colloid mill grinding refinement from coarse to fine is carried out after being beaten, colloid mill refines colloid mill stator for the first time and turns
The gap of son is 50-60 microns, and it is 10-20 microns that colloid mill refines colloid mill for second with the gap of rotor；
(5) by grinding after fresh slurry concentrated, to water content in 40%-50%；
(6) serosity after concentration is spray-dried, inlet temperature is 100-170 DEG C, atomizing pressure 0.3-0.4MPa,
65-90 DEG C of leaving air temp, obtains nourishing heart vegetable powder.
Preferably, above-mentioned plant calcium preparation, the cucumber seed powder are obtained by following methods：Semen Cucumidis sativi is picked up into miscellaneous washing
Only, dry, slow fire stir-fries to ripe perfume (or spice), pulverizing after cooling, cross 20-40 mesh sieves, obtain cucumber seed powder.
The preparation method of above-mentioned plant calcium preparation, concretely comprises the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 80-100 mesh is crushed to, is obtained final product.
The invention has the beneficial effects as follows：
Above-mentioned plant calcium preparation, each component comes from food, safe and free of toxic and side effects, and each component is reasonably combined, collaboration increases
Effect, as a kind of high plant calcium preparation of calcium content, easily absorbs, is not impairment of the kidney, while a large amount of plant total flavones that Herba Sedi Aizoon is rich in,
Jing science it is edible, to hypertension, cardiovascular and cerebrovascular disease etc. with very big assosting effect；Three kinds of nutritional labeling collective effects,
The calcium of high-quality can be provided for human body, calcium absorption is effectively facilitated, be most healthy, most safe, maximally effective source of replenishing the calcium；By nourishing heart
The purpose crushed after vegetable powder, cucumber seed powder and inulin mix homogeneously is to overcome cucumber seed powder because of its oiliness and Semen Cucumidis sativi shell
The toughness of dietary fiber, and the difficulty of caused independent disintegrating process, the larger defect of grinding particle size, raw material Herba Sedi Aizoon are employed
The processing technique for completing, overcomes its herbaceous taste, reduces astringent taste, and clean taste maintains preferable color and luster, is effectively kept
The nutritional labeling and biological activity of Herba Sedi Aizoon, improves absorbance of the human body to its nutritional labeling；Using colloid mill it is secondary
Refinement technology and spray drying treatment, not only increase fineness, improve mouthfeel, more improve the apparent absorptivity of calcium, promote
The absorption of human body.
Specific embodiment
Technical scheme of the present invention is further described with reference to specific embodiment.
Embodiment 1
A kind of plant calcium preparation, is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, wherein, nourishing heart vegetable powder 65kg, Semen Cucumidis sativi
Powder 20kg, inulin 20kg.
The preparation method of above-mentioned plant calcium preparation, concretely comprises the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 100 mesh are crushed to, are obtained final product.
Embodiment 2
A kind of plant calcium preparation, is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, wherein, nourishing heart vegetable powder 40kg, Semen Cucumidis sativi
Powder 30kg, inulin 25kg.
The preparation method of above-mentioned plant calcium preparation, concretely comprises the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 80 mesh are crushed to, are obtained final product.
Embodiment 3
A kind of plant calcium preparation, is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, wherein, nourishing heart vegetable powder 80kg, Semen Cucumidis sativi
Powder 10kg, inulin 10kg.
The preparation method of above-mentioned plant calcium preparation, concretely comprises the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 100 mesh are crushed to, are obtained final product.
Embodiment 4
A kind of plant calcium preparation, is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, wherein, nourishing heart vegetable powder 50kg, Semen Cucumidis sativi
Powder 15kg, inulin 20kg.
The preparation method of above-mentioned plant calcium preparation, concretely comprises the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 100 mesh are crushed to, are obtained final product.
Embodiment 5
A kind of plant calcium preparation, is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, wherein, nourishing heart vegetable powder 70kg, Semen Cucumidis sativi
Powder 20kg, inulin 15kg.
The preparation method of above-mentioned plant calcium preparation, concretely comprises the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 80 mesh are crushed to, are obtained final product.
In above-described embodiment 1-5, inulin is commercially available prod.
Nourishing heart vegetable powder is obtained by following methods：
(1) fresh and tender, ripe Herba Sedi Aizoon is selected to carry out roguing, cleaning；
(2) the Herba Sedi Aizoon fresh leaf after roguing, cleaning is completed in roller fixation machine, wherein about 100 DEG C of temperature, the time
For 4min；
(3) it is beaten in the Herba Sedi Aizoon input beater after completing；
(4) colloid mill grinding refinement from coarse to fine is carried out after being beaten, colloid mill refines colloid mill stator for the first time and turns
The gap of son is 50-60 microns, and it is 10-20 microns that colloid mill refines colloid mill for second with the gap of rotor；
(5) by grinding after fresh slurry concentrated, to water content 45% or so；
(6) serosity after concentration is spray-dried, inlet temperature is 100-170 DEG C, atomizing pressure 0.3-0.4MPa,
65-90 DEG C of leaving air temp, obtains nourishing heart vegetable powder.
Cucumber seed powder is obtained by following methods：Semen Cucumidis sativi is picked up into miscellaneous clean, drying, slow fire stir-fry to ripe perfume (or spice), cooling
Pulverizing, crosses 40 mesh sieves, obtains cucumber seed powder afterwards.
One of embodiment 1-5 each component consumption is increased or decreased according to same ratio, the weight portion of gained each component
Number relation belongs to protection scope of the present invention.
Above-described embodiment prescription analysis：
Herba Sedi Aizoon (Herba Sedi Aizoon) is a kind of preferable health-care vegetable, rich in proteins, carbohydrate, fat, thick fine
Dimension, carotene, vitamin B1, vitamin B2, vitamin C, calcium, phosphorus, ferrum, sitosterol, alkaloid, sedoheptose, flavonoid, have
The multiple components such as machine acid；It is a kind of high calcium vegetable of medicine-food two-purpose, its calcium content is up to 331 milligrams per hectogram, every in dry
Hectogram content is more up to 6740 milligrams, the natural plant water-soluble organic calcium that institute's calcic behaviour body easily absorbs, with natural shape
State is presented, the source calcareous as calcium replenishing preferably.A large amount of plant total flavones that Herba Sedi Aizoon is rich in simultaneously, the food of Jing science
With to hypertension, cardiovascular and cerebrovascular disease etc. with very big assosting effect.
Record according to " Compendium of Materia Medica " " Chinese Pharmacopoeia ", Semen Cucumidis sativi is the Main Ingredients and Appearance of Drug therapy synthetism, is pressed with continuous muscle
Bone, wind-dispelling, effect of expectorant.Cure mainly fracture, the injury of tendon and muscle, rheumatic arthralgia, old phlegm dyspnea.Calcium content in Semen Cucumidis sativi is high, human body pole
Easily absorb, and calcium phosphorus ration is very reasonable, additionally containing a large amount of vitamin and abundant mineral element, is human skeletal and people
Good nutrient in body, to the soreness of waist, backache, numbness of hands and feet, legs and feet cramp, rheumatism, arthritis, cervical spondylosiss, fracture, bone splits
There are alleviation and therapeutical effect well etc. disease and symptom.
Inulin is combined into complex with mineral, and is degraded in intestinal fermentation, and then discharges mineral, thus makes
Metal ion is more effectively absorbed.Research data shows that inulin can make Ca2+、Mg2+、Zn2+、Cu2+、Fe2+Deng mineral
Absorbance improves 20%.
It can be seen that, scientific combination of the above-mentioned plant calcium preparation by nourishing heart vegetable powder, cucumber seed powder and inulin is reasonably combined, and three
Kind of nutritional labeling mutually cooperates with collective effect, and the calcium of high-quality can be provided for human body, calcium absorption is effectively facilitated, and is most healthy, most
Safety, maximally effective source of replenishing the calcium.Its raw material Herba Sedi Aizoon employs the processing technique that completes of uniqueness, overcomes its herbaceous taste, subtracts
Astringent taste is lacked, clean taste maintains preferable color and luster, has been effectively kept the nutritional labeling and biological activity of Herba Sedi Aizoon, has carried
High absorbance of the human body to its nutritional labeling；And the secondary refinement technology of colloid mill and spray drying treatment of employing, not only increase
Fineness is added, has improved mouthfeel, more improved the apparent absorptivity of calcium, promote the absorption of human body；By nourishing heart vegetable powder, Semen Cucumidis sativi
The purpose crushed after powder and inulin mix homogeneously overcomes cucumber seed powder because of its oiliness and Semen Cucumidis sativi shell diet fiber
Toughness and caused independent disintegrating process is difficult, grinding particle size is larger defect.
Test example
1.1 clinical data
50 normal pregnancies, 20～38 years old, without other complication and complication, normal diet, without obvious monophagia, into reality
When testing, pregnant week is 12～20 weeks.
Method：Anemia of pregnant woman is divided into into two groups at random, test group 25 takes plant calcium preparation, 20g/ described in the embodiment of the present invention 1
Bag, wherein calcium element content are 400mg, and once a day, one bag every time, continuous oral is to childbirth.Matched group 25 was taken for the same period
With the first tire anemia of pregnant woman of commercially available gluconic acid- ca.
1.2 observation index
(1) a situation arises for clinical calcium deficiency symptom：There are the diseases such as lumbosacral pain, sural spasm, arthralgia before and after record treatment
Shape, with and without indicating whether calcium deficiency.
(2) two groups are surveyed blood calcium before calcium is taken on an empty stomach, and check blood calcium value is made comparisons within pregnant 37～40 weeks.
(3) pregnancy period medication compliance and Drug side reaction, each follow-up time are inquired medication situation and are had no adverse reaction.
1.3 clinical effectiveness
Two groups are checked blood calcium value in 37～40 weeks in gestation, and the calcium value of test group is significantly raised, and matched group calcium level without
Significant change.(P ＜ 0.01) statistically significant with matched group comparing difference, is shown in Table 1.
Table 1 replenish the calcium before with replenish the calcium after each group serum calcium compare (x ± s, mmol/L)
1.4 calcium deficiency symptoms
There is obvious calcium deficiency symptom, test group accounts for 16.0% for 4, and matched group 9 accounts for 36.0%, and test group is significantly lower than
Matched group, is shown in Table 2.
2 test group of table is compared with matched group calcium deficiency symptom
The above-mentioned detailed description carried out to a kind of plant calcium preparation and preparation method thereof with reference to embodiment, is illustrative
Rather than it is determinate, several embodiments can be included according to limited scope, therefore without departing from present general inventive concept
Under change and modifications, should belong within protection scope of the present invention.
Claims (5)
1. a kind of plant calcium preparation, it is characterised in that：It is made up of nourishing heart vegetable powder, cucumber seed powder and inulin, based on its parts by weight
Nourishing heart vegetable powder 40-80 parts, cucumber seed powder 10-30 parts, inulin 10-25 parts.
2. plant calcium preparation according to claim 1, it is characterised in that：65 parts of nourishing heart vegetable powder, Huang based on its parts by weight
20 parts of squash seed meal, 20 parts of inulin.
3. plant calcium preparation according to claim 1, it is characterised in that：The nourishing heart vegetable powder is obtained by following methods
's：
(1) fresh and tender, ripe Herba Sedi Aizoon is selected to carry out roguing, cleaning；
(2) the Herba Sedi Aizoon fresh leaf after roguing, cleaning is completed in roller fixation machine, wherein temperature is 90-110 DEG C, and the time is
2-5min；
(3) it is beaten in the Herba Sedi Aizoon input beater after completing；
(4) colloid mill grinding refinement from coarse to fine is carried out after being beaten, colloid mill refines colloid mill stator for the first time with rotor
Gap is 50-60 microns, and it is 10-20 microns that colloid mill refines colloid mill for second with the gap of rotor；
(5) by grinding after fresh slurry concentrated, to water content in 40%-50%；
(6) serosity after concentration is spray-dried, inlet temperature is 100-170 DEG C, atomizing pressure 0.3-0.4MPa, air-out
Temperature 65-90 DEG C, obtains nourishing heart vegetable powder.
4. plant calcium preparation according to claim 1, it is characterised in that：The cucumber seed powder is obtained by following methods
's：Semen Cucumidis sativi is picked up into miscellaneous clean, drying, slow fire stir-fry to ripe perfume (or spice), pulverizing after cooling, cross 20-40 mesh sieves, obtain cucumber seed powder.
5. the preparation method of plant calcium preparation described in claim 1, it is characterised in that：Concretely comprise the following steps：
(1) nourishing heart vegetable powder, cucumber seed powder and inulin are weighed for raw material by prescription amount；
(2) by nourishing heart vegetable powder, cucumber seed powder and inulin mix homogeneously, 80-100 mesh is crushed to, is obtained final product.
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Cited By (3)
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| CN107129352A (en) * | 2017-04-27 | 2017-09-05 | 广西棕海园林工程有限公司 | Calcium in Plants |
| CN111357861A (en) * | 2020-04-03 | 2020-07-03 | 天津和治友德制药有限公司 | Processing method of aizoon stonecrop herb |
| CN116035208A (en) * | 2023-03-06 | 2023-05-02 | 衢州合农心农业开发有限公司 | Gynura procumbens compound health-care liquid and preparation method thereof |
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| CN104982937A (en) * | 2015-07-31 | 2015-10-21 | 中科和素（天津）医药科技有限公司 | Composition for promoting sclerotin and periosteum repairing and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107129352A (en) * | 2017-04-27 | 2017-09-05 | 广西棕海园林工程有限公司 | Calcium in Plants |
| CN111357861A (en) * | 2020-04-03 | 2020-07-03 | 天津和治友德制药有限公司 | Processing method of aizoon stonecrop herb |
| CN116035208A (en) * | 2023-03-06 | 2023-05-02 | 衢州合农心农业开发有限公司 | Gynura procumbens compound health-care liquid and preparation method thereof |
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