CN106389738A - Traditional Chinese medicine granules for treating constipation - Google Patents
Traditional Chinese medicine granules for treating constipation Download PDFInfo
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- CN106389738A CN106389738A CN201611165822.0A CN201611165822A CN106389738A CN 106389738 A CN106389738 A CN 106389738A CN 201611165822 A CN201611165822 A CN 201611165822A CN 106389738 A CN106389738 A CN 106389738A
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- 206010010774 Constipation Diseases 0.000 title claims abstract description 32
- 239000003814 drug Substances 0.000 title claims abstract description 17
- 239000008187 granular material Substances 0.000 title abstract 4
- 239000002245 particle Substances 0.000 claims description 4
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 9
- 229940079593 drug Drugs 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- 238000010926 purge Methods 0.000 abstract description 3
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
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- 235000006508 Nelumbo nucifera Nutrition 0.000 abstract 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 abstract 1
- 240000005373 Panax quinquefolius Species 0.000 abstract 1
- 235000003140 Panax quinquefolius Nutrition 0.000 abstract 1
- 241001522232 Pinellia ternata Species 0.000 abstract 1
- 235000011034 Rubus glaucus Nutrition 0.000 abstract 1
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- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
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- KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/74—Rubiaceae (Madder family)
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- A61K36/746—Morinda
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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Abstract
The invention relates to traditional Chinese medicine granules for treating constipation. The traditional Chinese medicine granules are prepared from the following components: 2-3 parts of american ginseng, 10-20 parts of radix rehmanniae praeparata, 10-20 parts of rhizoma atractylodis macrocephalae, 12-25 parts of Chinese date, 12-17 parts of morinda officinalis, 10-20 parts of raspberry, 10-15 parts of liquorice, 10-20 parts of red orange, 6-10 parts of pinellia ternata, 10-20 parts of fructus gardeniae and 5-8 parts of lotus plumule. Through the coordination of the medicines, the traditional Chinese medicine granules provided by the invention realize the functions of purging heat and relaxing bowels and nourishing yin and moistening dampness and have the characteristics of exact curative effect, little toxic and side effects, convenience in taking and low cost in constipation treatment.
Description
Technical field
The present invention relates to a kind of beverage, particularly to a kind of instant particles as Chinese medicine treating constipation.
Background technology
Constipation is clinical common complicated symptom, is primarily referred to as defecation frequency minimizing, feces amount reduces, feces are dry and hard, row
Just laborious etc..Its reason is complicated, how with gastrointestinal function, species of ingesting and custom, living habit, environmental factorss, the mental status
Etc. relevant.The traditional Chinese medical science thinks, constipation is mainly caused by dryness-heat stagnating in the interior, depression and stagnation of QI, deficiency of body fluid and spleen-kidney vacuity cold.Constipation can
To affect the people of each age group, women is more than male, and old age is more than person between twenty and fifty.Because constipation sickness rate is high, the cause of disease is complicated, to patient
Bring a lot of worries, quality of life when constipation is serious, can be affected.The patient of general constipation can be entered using oral drugs or injection
Row treatment, but the stimulation to stomach for the oral drugs and the toxic and side effects to liver are all larger, and also medicine is easily subject to Digestive system
Destroy, also can because of the first pass effect of liver decreasing effect, absorb slow, onset is slow, injection also can produce toxic and side effects to patient, therefore
The therapeutic effect of most drug is all less desirable.
Content of the invention
The purpose of the present invention is to overcome a kind of prior art instant particles as Chinese medicine treating constipation of not enough offer.For realizing this
The purpose of invention, now depending on following technical scheme.This medicine is made up of the raw material of following weight:Radix Panacis Quinquefolii 2-3
Part, Radix Rehmanniae Preparata 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Fructus Jujubae 12-25, Radix Morindae Officinaliss 12-17 part, Fructus Rubi 10-20 part, Radix Glycyrrhizae 10 15
Part, Exocarpium Citri Rubrum 10-20 part, Rhizoma Pinelliae 6-10 part, Fructus Gardeniae 10-20 part, Plumula Nelumbiniss 5-8 part.
Fang Xie:
Radix Panacis Quinquefolii:Boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.For deficiency of vital energy yin deficiency, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, dry mouth larynx
Dry.
Radix Rehmanniae Preparata:Enrich blood YIN nourishing, beneficial essence fills out marrow.
The Rhizoma Atractylodis Macrocephalae:Dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, goes wet in taste, except gastric heat, strong taste, and enter diet, antiabortive.”
Fructus Jujubae:Warm in nature, sweet in the mouth, tool vigorate qi and replenish the blood, invigorating the spleen and regulating the stomach, wind effect.
Radix Morindae Officinaliss:Cure mainly impotence and seminal emission, uterus cold infertile, menoxenia, few abdomen crymodynia, rheumatic arthralgia, muscles and bones impotence.
Fructus Rubi:Effect:Supplementing the kidney to control the nocturnal reducing urination, nourishing the liver to improve visual acuity.
Radix Glycyrrhizae:Indication heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc..
Exocarpium Citri Rubrum:Regulating the flow of QI to ease the stomach, drying dampness to eliminate phlegm.
The Rhizoma Pinelliae:Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Fructus Gardeniae:Heat clearing away, pathogenic fire purging, removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea.
Plumula Nelumbiniss:Bitter in the mouth, cold in nature.Heat clearing away, eliminating heart-fire, blood pressure lowering.
The present invention all medicines cooperation, plays the effect of purging heat to relax the bowels, nourshing Yin and drynsessmoistening prescription altogether.Treatment constipation has determined curative effect,
Toxic and side effects are little, taking convenience, cheap feature.
The preparation method of the present invention is:
(1), to weigh medical material by prescription standby;
(2), standby pulverizing medicinal materials crossed 100 mesh obtain final product the present invention.
Specific embodiment
Weigh following raw material by prescription:Radix Panacis Quinquefolii 2-3 part, Radix Rehmanniae Preparata 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Fructus Jujubae 12-25,
Radix Morindae Officinaliss 12-17 part, Fructus Rubi 10-20 part, 10 15 parts of Radix Glycyrrhizae, Exocarpium Citri Rubrum 10-20 part, Rhizoma Pinelliae 6-10 part, Fructus Gardeniae 10-20 part,
Plumula Nelumbiniss 5-8 part.
The preparation method of the present invention is:
(1), to weigh medical material by prescription standby;
(2), standby pulverizing medicinal materials crossed 100 mesh obtain final product the present invention.
Instructions of taking of the present invention is:Day three times, 8 grams every time, warm water delivery service.It is within 15th a course for the treatment of.
Drug therapy constipation of the present invention clinical observation
1st, diagnostic criteria:1. meet《Practical internal medicine》In diagnostic criteria;2. defecation time is had to extend, during adjacent 2 defecations
Between be spaced > 72h, or just matter is dry and hard, and very then as sheep stool or agglomerate, defecation is laborious, or stool is not dry and hard and discharge difficult person
[2] ;3. through fibro-colonoscope or canel barium meal contrast examination exclusion knot, rectum organic disease.
2nd, clinical data:64 patients of clinical random selection, all patients are constipation and make a definite diagnosis.
3rd, Therapeutic Method:Day three times, 8 grams every time, warm water delivery service.It is within 15th a course for the treatment of.
4th, criterion of therapeutical effect:Cure:Stool is normal, and all symptoms all disappear;Effective:Constipation is obviously improved, interval time and
Just matter is close to normal, or stool is slightly dry and the infrequent defecation time within 72h;Effectively:The infrequent defecation time shortens 1 day or just
The dry and hard improvement of matter;Invalid:Constipation is not alleviated.
5th, therapeutic effect:Treat 64 using the present invention, result cures 51, effective 6, effective 3, invalid 4
Example, total effective rate is 93.7%.
Model case:
1st, Wang, female, 61 years old, in November, 2011 first visit.Abdominal distention, when hidden when pain, just can not be intended to, bitter taste xerostomia, stringy and thready pulse
Number.Long-term constipation, takes relieving constipation purgatives medicine thing usually, and effect is still, recently invalid, and stool does not solve for 5 days.Front doctor examine for
Habitual constipation.Feelings will is not smooth usually for patient, being insomnia more, have a sleepless night more very after constipation night.Lab testing no abnormality seen.It is diagnosed as
Constipation, because of long-term taking cathartic, produces drug resistance, dialectical for deficiency of YIN dry constipation of intestines.Give Drug therapy of the present invention.Medication 2 days
Defecate 1 time afterwards, abdominal distention and pain substantially mitigates.After taking 3 days again, defecate 1 time again, receive food fragrant, distention and fullness in the abdomen disappears substantially.Continuous
After taking l0 days, stool 1 time, just soft smooth profit, consolidate 10 daily, and all diseases eliminate and obtain recovery from illness.Subsequently dose is decremented to dimension
Hold below dosage, take all the year round.Follow-up 1 year, constipation symptom disappears substantially.
2nd, Korea Spro, man, 58 years old, first visit in August, 2010.More than 10 years of constipation, 5~6 days 1 time.Once took repeatly
The relieving constipation purgatives medicine thing such as phenolphthalein tablet, SANHUANG PIAN, Folium Sennae, can temporarily produce effects, and be discontinued then constipation as before.Feelings will is not usually for patient
Freely, being insomnia night more, have a sleepless night more very after constipation.Examine and see:Stool do not solve within 5 days, abdominal distention, when hidden when pain, just can not be intended to, bitter taste xerostomia,
Dysphoria with feverish sensation in the chest palms and soles, night dormancy is slept less, and body of the tongue is light red, tongue no Tianjin less, thready pulse decimal.Lab testing no abnormality seen.It is diagnosed as deficiency of YIN intestinal
Dry constipation.Give Drug therapy of the present invention, be within ten days a course for the treatment of.After 15 days, two examine.Symptom disappears substantially.Continue and take 20 days, consolidate
Admittedly 2 courses for the treatment of of treatment.9 middle of the month three in 2010 examine, and all symptoms of patient are wholly absent.Subsequently dose is decremented to maintenance
Below dosage, take all the year round.Follow-up 2 years, constipation symptom disappears substantially.
3rd, close certain, man, 61 years old.April 11 first visit in 2009:Patient's aged debility, average 4 days/time of defecating, row
Just difficult, excrement matter is stiff.With indistinct abdominal part distending pain, dizziness headache, loss of appetite, sleep disorder, body of the tongue is light red, tongue no Tianjin less,
Thready pulse decimal.Lab testing no abnormality seen.It is diagnosed as deficiency of YIN dry constipation of intestines.Give Drug therapy of the present invention, be within ten days a treatment
Journey.22 days two April in 2009 examines.Symptom disappears substantially.Continue and take 10 days, one course for the treatment of of after treatment.May 2 in 2009
Day three examines, and all symptoms of patient disappear.Subsequently dose is decremented to below maintenance dose, takes all the year round.Follow-up 3 years, all diseases
Shape disappears substantially.
Claims (1)
1. a kind of instant particles as Chinese medicine treating constipation is it is characterised in that it is to be prepared from the following raw materials in parts by weight:Radix Panacis Quinquefolii 2-3
Part, Radix Rehmanniae Preparata 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Fructus Jujubae 12-25, Radix Morindae Officinaliss 12-17 part, Fructus Rubi 10-20 part, Radix Glycyrrhizae 10 15
Part, Exocarpium Citri Rubrum 10-20 part, Rhizoma Pinelliae 6-10 part, Fructus Gardeniae 10-20 part, Plumula Nelumbiniss 5-8 part.
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CN201611165822.0A CN106389738A (en) | 2016-12-16 | 2016-12-16 | Traditional Chinese medicine granules for treating constipation |
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CN201611165822.0A CN106389738A (en) | 2016-12-16 | 2016-12-16 | Traditional Chinese medicine granules for treating constipation |
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