CN106344432A - Tooth whitening gel and preparation method and application thereof - Google Patents
Tooth whitening gel and preparation method and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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Abstract
The invention provides tooth whitening gel. The gel comprises the following components in parts by weight: 4-8 parts of an oxidizing agent, 1.5-5.5 parts of thickening aids, 30-40 parts of deionized water, 45-55 parts of glycerin, 0.01-0.5 part of menthol, 1-5 parts of xylitol and 0.5-4 parts of triethanolamine. The invention also provides a method for preparing the tooth whitening gel. The method comprises the following steps: sequentially pouring the oxidizing agent, thickening aids, deionized water, glycerin, menthol and xylitol into a container on an assembly line by adopting a perfusion method, sealing the container after all the components are completely poured, standing under the condition of the temperature of 10-20 DEG C for 20-30 hours, and molding. The invention also relates to application of the tooth whitening gel in improvement of tooth staining, wherein the tooth staining comprises extrinsic staining and intrinsic staining.
Description
Technical field
The present invention relates to field of health care products, in particular to a kind of tooth whitening gel and preparation method thereof and its should
With.
Background technology
The tooth of dyeing or variable color is considered as cosmetics infringement.Tooth whitening is in order to improve the outward appearance of tooth and to carry out
Cosmetic treatments.Other materials tooth being carried out with whitening to remove coffee, medicated cigarette and make tooth permanent stain or variable color
Effect.The different technologies of tooth whitening or bleaching are known and there is the relatively simple journey improving dyeing teeth appearance
Sequence.This program can be carried out in dental clinic, office or living environment.
The time that the comfort level of handled people can be shortened by bleaching in dental bleaching processing procedure improves.Most common
Bleach be peroxide, including but not limited to hydrogen peroxide, urea peroxide, Dexol and SODIUM PERCARBONATE.Shortening is processed
The simplest method of time is to increase the concentration of peroxide.However, this may lead to stimulate and or even gingiva or lip
Or some damages of other soft tissues.
The another way of bleaching teeth is more quickly, anti-by the heat or acceleration by light chemistry relevant with bleaching process
Should.Known heat and light are alone or in combination to accelerate chemical reaction.There are the different bleaching compositions of bleaching activity of increase
It is exploited for using cooperatively with heat or light.
Whitening gelatin of the prior art is generally difficult to preserve for a long time at a normal temperature, generally exceedes in ambient temperature
Aquation quickly when 30 DEG C, affects using effect.Additionally, tooth whitening gel of the prior art often only focuses on whitening effect,
And ignore other aspect demands of dental care, accordingly, it would be desirable to a kind of whitening gelatin is on the premise of having good whitening function,
There is the effect preventing hemodia simultaneously.
In view of this, the special proposition present invention.
Content of the invention
The first object of the present invention is to provide a kind of compound forward osmosis membrane, and described compound forward osmosis membrane can carry effectively
High water flux, and reach very high salt-stopping rate, and there is antibacterial action.
The second object of the present invention is to provide a kind of preparation method of described compound forward osmosis membrane, the method operation letter
Single, selected parameter is particularly suitable for preparing the compound forward osmosis membrane that the present invention provides.
In order to realize the above-mentioned purpose of the present invention, spy employs the following technical solutions:
One aspect of the present invention is related to a kind of tooth whitening gel, the raw material of described gel include by weight with
Lower component: oxidant 4-8 part, thickening adjuvant 1.5-5.5 part, deionized water 30-40 part, glycerol 45-55 part, menthol 0.01-
0.5 part, xylitol 1-5 part and triethanolamine 0.5-4 part.
Oxidant is contained, the coloring thing of oxidant and dental surface during use in the tooth gel compositionss of the present invention
There is chemical reaction in matter, play whitening effect after being oxidized, and principle is similar to bleaching.Wherein glycerol and the combination of thickening adjuvant, can
So that compositionss can form gel after mixing, with the addition of in component menthol and xylitol its on the one hand as sweetener,
The taste property of preparation can be improved；On the other hand as polyhydric alcohol, play the effect of water-retaining component.Wherein, being related to of xylitol
The metabolic mechanism of streptococcic biochemistry is characterised by lethal synthesis, leads to the pathogenic microorganism weakening activity and changes
Kind oral cavity organs condition, can play certain anti-caries effect.
Triethanolamine is also added, polyhydric alcohol amine plays the effect of buffering ph in the composition, by component in the present invention
Ph maintains the scope of suitable preservation, and is capable of the reaction of accelerated oxidation thing and dental surface pigment in use.
Preferably, the raw material of described gel include by weight following components: oxidant 5-7 part, thickening adjuvant
2-4.5 part, deionized water 32-38 part, glycerol 48-52 part, menthol 0.1-0.3 part, xylitol 2-4 part, triethanolamine 1-3
Part.
Preferably, described oxidant is hydrogen peroxide, urea peroxide, any one in SODIUM PERCARBONATE.
The oxidant of the present invention adopts peroxide, and it can be decomposed by the various mode such as illumination in use, produces oxygen
Gas, and and then aoxidize dental surface pigmentation, play the effect of tooth whitening.
Preferably, described thickening adjuvant is Carbomer it is preferable that described thickening adjuvant is Acritamer 940 or Carbomer
941.
Preferably, the raw material going back gel also includes the composition for desensitizing teeth of 0.1-0.5 part by weight.
It is possible to during tooth-whitening cause hemodia, on the other hand, hemodia is also crowd instantly in itself
Easily send out subhealth symptom, add hemodia compositionss therefore in component and can effectively improve both the above phenomenon,
Realize while tooth-whitening, improving the symptom of hemodia.
Preferably, described composition for desensitizing teeth includes following components: sodium fluoride, paraformaldehyde, hydroxyethyl cellulose, goes
Ionized water is it is preferable that the weight ratio between described component is (1-3): (5-8): (10-20): 100.
Using sodium fluoride as the Fluorine source of composition for desensitizing kind in the present invention, fluorion itself using excessive when can lead to tooth
Coloring, but the present invention introduces fluorion while tooth-whitening, and using it, dental caries and hemodia aspect are controlled
Treatment acts on, and can effectively maximize favourable factors and minimize unfavourable ones, reach the health care in terms of whitening carries out dental caries and antiallergic simultaneously.
Another aspect of the present invention is related to the preparation method of described tooth whitening gel, the method comprising the steps of:
Streamline irrigates described oxidant, thickening adjuvant, deionized water, glycerol, Herba Menthae using method for filling successively into container
Alcohol, xylitol, after the completion of all components perfusion, container are sealed and stand 20-30h molding under conditions of 10-20 DEG C.
The preparation method maturation of the present invention is controlled, whole-course automation produce, whole set process strictly control each step when
Between volume production can be carried out with high quality and high efficiency.
Preferably, irrigating interval time between each component is 10-25 minute.
Preferably, methods described is further comprising the steps of, after the completion of xylitol perfusion, before carrying out container sealing, fills
Note composition for desensitizing teeth.
Another aspect of the present invention is related to application in improving tooth staining for the described tooth whitening gel, wherein said tooth
Tooth coloring includes staining and endogenouss coloring.
Compared with prior art, the invention has the benefit that
(1) the tooth whitening gel of the present invention has good tooth whitening effect, and can be long at relatively high temperatures
Phase preserves and does not affect whitening effect；
(2) the tooth whitening gel of the present invention also has antiallergic effect, takes into account the health of tooth while whitening；
(3) preparation method of the present invention is reliable and stable, and institute is particularly suitable for preparing described tooth whitening using process detail and coagulates
Glue；
(4) the tooth whitening gel of the present invention is respectively provided with whitening function for endogenouss and ectogenic tooth staining.
Specific embodiment
Below in conjunction with embodiment, embodiment of the present invention is described in detail, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and be not construed as limiting the scope of the present invention.Unreceipted concrete in embodiment
Condition person, the condition according to normal condition or manufacturer's suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, are
Can be by the commercially available conventional products bought and obtain.
Embodiment 1
Prepare tooth whitening gel according to following steps
Prepare the following raw material of parts by weights meter: 8 parts of hydrogen peroxide, 5.5 parts of Acritamer 940,40 parts of deionized water, sweet
55 parts of oil, 0.5 part of menthol, 5 parts of xylitol and 4 parts of triethanolamine.
Production technology is irrigated using pipeline system, workshop room temperature is maintained at 18-28 DEG C, streamline press add raw material and
Time sets, and arranges a ultraviolet radiation for sterilizing and disinfecting operating point, seven perfusion operating points, and an encapsulation process operating point.
Direct labor puts into the plastic, transparent container bottle of batch on streamline, with the operating of streamline, plastic containers
Reach through first disinfection by ultraviolet light point, the ultraviolet sterilization antivirus that all plastic, transparent container bottle are carried out 30 minutes is processed.
Enter filling type production line after disinfecting, reach first perfusion point, machine conduit is directed at container
Bottle injection material composition hydrogen peroxide, after the completion of injection, container bottle moves to second perfusion point, the second filling with material distributing machine
Note point injects the Carbomer of corresponding ratio toward in bottle again by machine conduit, continues successively, the transmission being separated by between perfusion point
Time maintains 10 minutes, and the order of perfusion presses hydrogen peroxide, Carbomer, deionized water, glycerol, menthol, xylitol, three second
Hydramine is irrigated.
Carry out encapsulation process, the raw material of perfusion produces fusion in filling process, forms gel, after sealing after the completion of perfusion
Carry out storage process, the time is 20h, gel forming in the static storage reservoir with 15 DEG C about.
Embodiment 2
Prepare tooth whitening gel according to following steps
Prepare the following raw material of parts by weights meter: urea peroxide, 1.5 parts of Carbopol 941,30 parts of deionized water, glycerol 45
Part, 0.01 part of menthol, 1 part of xylitol and 0.5 part of triethanolamine, 0.1 part of composition for desensitizing teeth.
Wherein, composition for desensitizing teeth be sodium fluoride, paraformaldehyde, hydroxyethyl cellulose, deionized water, described group point it
Between weight than for 1:5:10:100.
Production technology is irrigated using pipeline system, workshop room temperature is maintained at 18-28 DEG C, streamline press add raw material and
Time sets, and arranges a ultraviolet radiation for sterilizing and disinfecting operating point, seven perfusion operating points, and an encapsulation process operating point.
Direct labor puts into the plastic, transparent container bottle of batch on streamline, with the operating of streamline, plastic containers
Reach through first disinfection by ultraviolet light point, the ultraviolet sterilization antivirus that all plastic, transparent container bottle are carried out 30 minutes is processed.
Enter filling type production line after disinfecting, reach first perfusion point, machine conduit is directed at container
Bottle injection material composition hydrogen peroxide, after the completion of injection, container bottle moves to second perfusion point, the second filling with material distributing machine
Note point injects the Carbomer of corresponding ratio toward in bottle again by machine conduit, continues successively, the transmission being separated by between perfusion point
Time maintains 10 minutes, and the order of perfusion presses hydrogen peroxide, Carbomer, deionized water, glycerol, menthol, xylitol, three second
Hydramine is irrigated.
Carry out encapsulation process, the raw material of perfusion produces fusion in filling process, forms gel, after sealing after the completion of perfusion
Carry out storage process, the time is 24h, gel forming in the static storage reservoir with 10 DEG C about.
Embodiment 3
Prepare tooth whitening gel according to following steps
Prepare the following raw material of parts by weights meter: 5 parts of SODIUM PERCARBONATE, 2 parts of Acritamer 940,32 parts of deionized water, glycerol
48 parts, 0.1 part of menthol, 2 parts of xylitol and 1 part of triethanolamine, 0.5 part of composition for desensitizing teeth.
Wherein, composition for desensitizing teeth be sodium fluoride, paraformaldehyde, hydroxyethyl cellulose, deionized water, described group point it
Between weight than for 3:8:20:100.
Production technology is irrigated using pipeline system, workshop room temperature is maintained at 18-28 DEG C, streamline press add raw material and
Time sets, and arranges a ultraviolet radiation for sterilizing and disinfecting operating point, seven perfusion operating points, and an encapsulation process operating point.
Direct labor puts into the plastic, transparent container bottle of batch on streamline, with the operating of streamline, plastic containers
Reach through first disinfection by ultraviolet light point, the ultraviolet sterilization antivirus that all plastic, transparent container bottle are carried out 30 minutes is processed.
Enter filling type production line after disinfecting, reach first perfusion point, machine conduit is directed at container
Bottle injection material composition hydrogen peroxide, after the completion of injection, container bottle moves to second perfusion point, the second filling with material distributing machine
Note point injects the Carbomer of corresponding ratio toward in bottle again by machine conduit, continues successively, the transmission being separated by between perfusion point
Time maintains 15 minutes, and the order of perfusion presses hydrogen peroxide, Carbomer, deionized water, glycerol, menthol, xylitol, three second
Hydramine is irrigated.
Carry out encapsulation process, the raw material of perfusion produces fusion in filling process, forms gel, after sealing after the completion of perfusion
Carry out storage process, the time is 30h, gel forming in the static storage reservoir with 20 DEG C about.
Embodiment 4
Prepare tooth whitening gel according to following steps
Prepare the following raw material of parts by weights meter: 7 parts of hydrogen peroxide, 4.5 parts of Carbopol 941,38 parts of deionized water, sweet
52 parts of oil, 0.3 part of menthol, 4 parts of xylitol and 3 parts of triethanolamine, 0.3 part of composition for desensitizing teeth.
Wherein, composition for desensitizing teeth be sodium fluoride, paraformaldehyde, hydroxyethyl cellulose, deionized water, described group point it
Between weight than for 2:6:15:100.
Production technology is irrigated using pipeline system, workshop room temperature is maintained at 18-28 DEG C, streamline press add raw material and
Time sets, and arranges a ultraviolet radiation for sterilizing and disinfecting operating point, seven perfusion operating points, and an encapsulation process operating point.
Direct labor puts into the plastic, transparent container bottle of batch on streamline, with the operating of streamline, plastic containers
Reach through first disinfection by ultraviolet light point, the ultraviolet sterilization antivirus that all plastic, transparent container bottle are carried out 30 minutes is processed.
Enter filling type production line after disinfecting, reach first perfusion point, machine conduit is directed at container
Bottle injection material composition hydrogen peroxide, after the completion of injection, container bottle moves to second perfusion point, the second filling with material distributing machine
Note point injects the Carbomer of corresponding ratio toward in bottle again by machine conduit, continues successively, the transmission being separated by between perfusion point
Time maintains 25 minutes, and the order of perfusion presses hydrogen peroxide, Carbomer, deionized water, glycerol, menthol, xylitol, three second
Hydramine is irrigated.
Carry out encapsulation process, the raw material of perfusion produces fusion in filling process, forms gel, after sealing after the completion of perfusion
Carry out storage process, the time is 20h, gel forming in the static storage reservoir with 15 DEG C about.
Embodiment 5
Prepare tooth whitening gel according to following steps
Prepare the following raw material of parts by weights meter: 6 parts of hydrogen peroxide, 308 parts of Carbopol 941,35 parts of deionized water, sweet
50 parts of oil, 0.2 part of menthol, 3 parts of xylitol and 2 parts of triethanolamine, 0.2 part of composition for desensitizing teeth.
Wherein, composition for desensitizing teeth be sodium fluoride, paraformaldehyde, hydroxyethyl cellulose, deionized water, described group point it
Between weight than for 2:8:15:100.
Production technology is irrigated using pipeline system, workshop room temperature is maintained at 18-28 DEG C, streamline press add raw material and
Time sets, and arranges a ultraviolet radiation for sterilizing and disinfecting operating point, seven perfusion operating points, and an encapsulation process operating point.
Direct labor puts into the plastic, transparent container bottle of batch on streamline, with the operating of streamline, plastic containers
Reach through first disinfection by ultraviolet light point, the ultraviolet sterilization antivirus that all plastic, transparent container bottle are carried out 30 minutes is processed.
Enter filling type production line after disinfecting, reach first perfusion point, machine conduit is directed at container
Bottle injection material composition hydrogen peroxide, after the completion of injection, container bottle moves to second perfusion point, the second filling with material distributing machine
Note point injects the Carbomer of corresponding ratio toward in bottle again by machine conduit, continues successively, the transmission being separated by between perfusion point
Time maintains 20 minutes, and the order of perfusion presses hydrogen peroxide, Carbomer, deionized water, glycerol, menthol, xylitol, three second
Hydramine is irrigated.
Carry out encapsulation process, the raw material of perfusion produces fusion in filling process, forms gel, after sealing after the completion of perfusion
Carry out storage process, the time is 24h, gel forming in the static storage reservoir with 15 DEG C about.
Experimental example 1
Choose the volunteer of 200 tooth stainings, be equally divided into 5 groups, the tooth using preparation in embodiment 1-5 is beautiful respectively
White gel is that the volunteer of tooth staining carries out tooth whitening, asks volunteer to a month inner teeth gear after whitening effect and whitening
Whether allergic phenomena occurs or whether the existing allergic phenomena of tooth obtains improving the evaluation and test carrying out satisfaction, statistics is satisfied with people
Number, as shown in the table:
It can be seen that, the tooth whitening gel prepared using the scheme in the present invention is very excellent for the effect of tooth whitening
Show, and, with the addition of desensitization composition after tooth gel while tooth-whitening more can effectively act as prevent and improve
The effect of hemodia symptom.
Experimental example 2
Slowly certain, male, 29 years old, people from Beijing, and due to smoking, the exogenous jaundice of tooth, using the equal effect of multiple toothwash methods
Typically, tooth staining is more serious.
After the tooth whitening Gel Treatment tooth staining of the present invention, tooth staining disappears, effect is significant.
Experimental example 3
Zhang, man, 35 years old, people from Shanghai City, tetracycline pigmentation teeth, carry out renovating equal effect undesirable using multiple means.Pass through
After the tooth whitening Gel Treatment tooth staining of the present invention, tetracycline pigmentation teeth decoloration, whitening effect is notable.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's
Many other changes can be made in the case of spirit and scope and change.It is, therefore, intended that in the following claims
Including all such changes and modifications belonging in the scope of the invention.
Claims (10)
1. a kind of tooth whitening gel is it is characterised in that the raw material of described gel includes following components by weight: oxidation
Agent 4-8 part, thickening adjuvant 1.5-5.5 part, deionized water 30-40 part, glycerol 45-55 part, menthol 0.01-0.5 part, xylitol
1-5 part and triethanolamine 0.5-4 part.
2. tooth whitening gel according to claim 1 is it is characterised in that the raw material of described gel is included by weight
Following components: oxidant 5-7 part, thickening adjuvant 2-4.5 part, deionized water 32-38 part, glycerol 48-52 part, menthol
0.1-0.3 part, xylitol 2-4 part, triethanolamine 1-3 part.
3. tooth whitening gel according to claim 1 is it is characterised in that described oxidant is hydrogen peroxide, peroxidating
Any one in urea, SODIUM PERCARBONATE.
4. tooth whitening gel according to claim 1 it is characterised in that described thickening adjuvant be Carbomer it is preferable that
Described thickening adjuvant is Acritamer 940 or Carbopol 941.
5. tooth whitening gel according to claim 1 is it is characterised in that the raw material going back gel is also included by weight
The composition for desensitizing teeth of 0.1-0.5 part.
6. tooth whitening gel according to claim 5 is it is characterised in that described composition for desensitizing teeth is included with the following group
Point: sodium fluoride, paraformaldehyde, hydroxyethyl cellulose, deionized water are it is preferable that the weight ratio between described component is (1-3):
(5-8): (10-20): 100.
7. the preparation method of the tooth whitening gel described in any one of claim 1-4 is it is characterised in that methods described includes
Following steps: on streamline successively using method for filling irrigate into container described oxidant, thickening adjuvant, deionized water,
Glycerol, menthol, xylitol, after the completion of all components perfusion, container are sealed and stand 20-30h under conditions of 10-20 DEG C
Molding.
8. method according to claim 7 is it is characterised in that divide for 10-25 the interval time irrigating between each component
Clock.
9. method according to claim 7, it is characterised in that methods described is further comprising the steps of, irrigates in xylitol
After the completion of, before carrying out container sealing, irrigate composition for desensitizing teeth.
10. application in improving tooth staining for the tooth whitening gel described in any one in claim 1-6, wherein said tooth
Tooth coloring includes staining and endogenouss coloring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610974062.1A CN106344432A (en) | 2016-11-07 | 2016-11-07 | Tooth whitening gel and preparation method and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610974062.1A CN106344432A (en) | 2016-11-07 | 2016-11-07 | Tooth whitening gel and preparation method and application thereof |
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| CN106344432A true CN106344432A (en) | 2017-01-25 |
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| CN201610974062.1A Pending CN106344432A (en) | 2016-11-07 | 2016-11-07 | Tooth whitening gel and preparation method and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233265A (en) * | 2017-08-09 | 2017-10-10 | 周善永 | Strong tooth bacteriostatic gel |
| CN108542800A (en) * | 2018-07-07 | 2018-09-18 | 广东第二师范学院 | A kind of tooth whitening gel and its preparation and application |
| CN108904314A (en) * | 2018-10-09 | 2018-11-30 | 苏州清馨健康科技有限公司 | A kind of tooth whitening gel formula and preparation method |
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| CN101829026A (en) * | 2010-05-11 | 2010-09-15 | 李少君 | Composition for clearing tooth stains |
| CN101829329A (en) * | 2010-05-11 | 2010-09-15 | 李少君 | Tooth antiallergic composition |
| CN103301031A (en) * | 2012-03-06 | 2013-09-18 | 远东新世纪股份有限公司 | Tooth whitening gel |
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| CN101829026A (en) * | 2010-05-11 | 2010-09-15 | 李少君 | Composition for clearing tooth stains |
| CN101829329A (en) * | 2010-05-11 | 2010-09-15 | 李少君 | Tooth antiallergic composition |
| CN103301031A (en) * | 2012-03-06 | 2013-09-18 | 远东新世纪股份有限公司 | Tooth whitening gel |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233265A (en) * | 2017-08-09 | 2017-10-10 | 周善永 | Strong tooth bacteriostatic gel |
| CN108542800A (en) * | 2018-07-07 | 2018-09-18 | 广东第二师范学院 | A kind of tooth whitening gel and its preparation and application |
| CN108904314A (en) * | 2018-10-09 | 2018-11-30 | 苏州清馨健康科技有限公司 | A kind of tooth whitening gel formula and preparation method |
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Application publication date: 20170125 |