CN106333887A

CN106333887A - Plant extract having acne removal function and preparation method and application thereof

Info

Publication number: CN106333887A
Application number: CN201610762537.0A
Authority: CN
Inventors: 陈燕兰
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-08-30
Filing date: 2016-08-30
Publication date: 2017-01-18

Abstract

The invention belongs to the field of skin care and particularly relates to a plant extract having an acne removal function and a preparation method and application thereof. The plant extract having the acne removal function is prepared from raw material ingredients including marigold, achillea sibirca, pomegranate peel, licorice roots, rhizoma coptidis and coptis chinensis. The raw materials are reasonable in compatibility, different effective active ingredients produce a synergistic effect, the medicinal properties of the effective active ingredients are greatly excited, a medical effect is mild, no side effect is produced, and the plant extract integrates pore clearing, hair follicle clearing, oil secretion reduction, skin oil absorption and oil secretion balancing and has the effects of preventing and dissolving acnes, reducing hyperpigmentation, reliving skin inflammation and reducing cutaneous sensibility. In addition, the extract further has the effects of playing super-strong heating capability, sterilizing, astringing a wound, treating and preventing inflammation, pimples, coarse pores and scars and repairing the scars, can rapidly kill epidermis bacteria, hair follicle root bacillus and the like and has bacterium resistance and bacteriostasis effect.

Description

A kind of have plant extract of acne-removal function and preparation method and application

Technical field

The invention belongs to skin care field is and in particular to a kind of have plant extract of acne-removal function and preparation method thereof With application.

Background technology

Comedo, acne, skin sore etc. are medically referred to as acne, are a kind of common sebaceous gland chronic diseases, according to statistics The adult that there are about 80% once suffered from comedo in adolescence, and age of onset mostly typically was for 14～30 one full year of life.Its origin cause of formation is During adolescence, internal hormone can stimulate hair growth, and smegma is vigorous, leads to clogging of pores to form acne Core micropowder pierces.Micropowder thorn is invisible, and micropowder thorn grows skin surface needs 7 to 9 months from being formed to Trophophase.Micropowder thorn blocking pore induction inflammation, be pimple, pustule, tuberosity and cyst originate root.Traditional treatment is simply clear Except the acne on surface, and micropowder thorn stops growing for a period of time, then defines the situation of acne recurrent exerbation.

Lead to the formation mainly following factor of skin sore: (1) internal androgen secretion is excessive, exdermoptosis, and sebum divides Secrete excessive drainage difficulty, be deposited in hair follicle and form fat bolt.Long secondary bacterial infection, causes inflammatory around pilosebaceous unit anti- Should, form pimple or pustule, i.e. skin sore.(2) relevant with heredity, typically there is family history.(3) dyshormonia, dyspepsia, god Through system disorders.Picked-up is higher fatty acid, the food of high sugar and maror are its predisposing factors.(4) there are other diseases, lead to body Endotoxin cannot be discharged and be caused small pox, and modal is exactly constipation.(5) in time or improperly skin cleaning-nursing.For example, Excessively cleaning skin leads to skin to lose the faintly acid protection of natural sebum film and leads to bacterial infection and long pox, does not periodically chamfer Matter leads to horny layer to pile up blocked up, blocking pore and lead to bacterium infection.So, anti-acne should be from oil-control, antibacterial, cleaning, heat clearing away The aspect comprehensive control such as removing toxic substances, blood stasis-eliminating and stagnation-dissipating.

General treatment method mainly reaches the purpose of mitigation symptoms to a certain extent by changing dietary habit, if When running into serious situation, medicine must be coordinated to be treated.And product for resolving poxes effect of being sold on the market now is single, not only Effect is not notable, but also has certain side effect, and such patient is using it is possible to even more serious, thus disobeying later Carry on the back the original intention for the treatment of.At present, modern medicine mainly should using the treatment such as androgen antagonist, antibiotic, retinoid medicine Disease, has certain curative effect, but also has more apparent side effect, and such as liver function damage, teratogenesis, osteogenesis are slow, endocrine regulation, property work( Can be impacted etc..

Content of the invention

In order to overcome the deficiencies in the prior art and shortcoming, the primary and foremost purpose of the present invention is to provide one kind to have acne-removal function Plant extract.

Another object of the present invention is to providing the preparation method of the above-mentioned plant extract with acne-removal function.

It is still another object of the present invention to provide the application of the above-mentioned plant extract with acne-removal function.

The purpose of the present invention is achieved through the following technical solutions:

A kind of plant extract with acne-removal function, is prepared by following raw material components in parts by mass:

The described plant extract with acne-removal function, is preferably prepared into by following raw material components in parts by mass Arrive:

The preparation method of the described plant extract with acne-removal function, comprises the steps of:

(1) Flos Inulae, common milfoil, Radix Hamamelidis Molliss, Pericarpium Granati, Radix Glycyrrhizae, Cortex Phellodendri and Rhizoma Coptidis are separately dried, pulverize and sieve, obtain To Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder, Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder and Cortex Phellodendri coarse powder are carried out co₂Surpass and face Boundary's fluid extraction；Wherein, Extracting temperature is 35～45 DEG C, and extraction pressure is 18～30mpa, and extraction time is 1～2.5h, co₂ Flow velocity is 10～20l/h, and separation temperature is 35～45 DEG C, and separating pressure is 5～10mpa；Collect extract, obtain plant extract Thing 1；

(3) plant residue after step (2) extraction is carried out co again₂Supercritical fluid extraction；Wherein, dehydrated alcohol is made For entrainer, Extracting temperature is 40～50 DEG C, and extractions pressure is 20～30mpa, and extraction time is 1～2.5h, co₂Flow velocity is 10 ～20l/h, separation temperature is 40～50 DEG C, and separating pressure is 5～10mpa；Collect extract, obtain plant extract 2；

(4) plant residue after step (3) extraction is mixed with Radix Glycyrrhizae coarse powder, Rhizoma Coptidis coarse powder (i.e. remaining ingredient), add water After soaking 6～12h, 80～100 DEG C of heating and refluxing extraction 2～4 times, 1～2h every time, then filters, merging filtrate, filtrate is dense Contracting, cooling；Then, under stirring, add dehydrated alcohol, make ethanol content in the mixed liquor finally giving reach 70～80%； Airtight place to precipitation completely, remove precipitation, the supernatant decompression recycling ethanol obtaining, obtain concentrated solution；

(5) plant extract 2 prepared to the prepared plant extract 1 of step (2), step (3) and step (4) are obtained Concentrated solution mix homogeneously, obtains the plant extract with acne-removal function；

Sieving described in step (1) preferably crosses 10～20 mesh sieves；

Co described in step (2)₂The condition of supercritical fluid extraction is preferably: Extracting temperature is 40 DEG C, extracts pressure For 20mpa, extraction time is 2h, co₂Flow velocity is 15l/h, 40 DEG C of separation temperature, and separating pressure is 6mpa；

Co described in step (3)₂The condition of supercritical fluid extraction is preferably: Extracting temperature is 45 DEG C, extracts pressure For 25mpa, extraction time is 2h, co₂Flow velocity is 15l/h, 45 DEG C of separation temperature, and separating pressure is 8mpa；

The time of the immersion described in step (4) is preferably 10h；

The condition of the heating and refluxing extraction described in step (4) is preferably: 100 DEG C of heating and refluxing extraction 3 times, every time 1.5h；

Preferably shorter than 40 DEG C of temperature after cooling described in step (4)；

The condition of the airtight placement described in step (4) is preferably 4～10 DEG C of placement 12～48h；

The relative density of the concentrated solution described in step (4) is 1.1～1.25；

Application in skin care field for the described plant extract with acne-removal function；

The consumption having the plant extract of acne-removal function in described skin care item is 0.1～10% (w/w), and preferable amount is 1～5% (w/w)；

In described skin care item, in addition to above-mentioned required composition, can coordinate as suitably desired generally in cosmetics Used in composition, for example, the matrix components such as other whitening agents, wetting agent, antioxidant, surfactant, alcohols, water；

The dosage form of described skin care item is preferably solution, suspension, emulsion, cream, paste, gel, milk, skin protection Liquid, powder, fancy soap, oil, dry powder, foundation emulsion, wet-milling or spray；

The principle of the present invention:

The flower of Flos Inulae, leaf have antiinflammatory, antibacterial action, particularly preferable to staphylococcuses, streptococcus effect；Punica granatum L. leatherware There are relieving diarrhea with astringents, hemostasis, anthelmintic, contain multiple alkaloids in the bright Pericarpium Granati of modern study outcome table, there is broad-spectrum antibacterial action, And it is referred to as, containing multiple, the polyhydric phenols of matter of mixing, there is good antioxidation, Controlling oil effect, wound surface is healed Conjunction has good facilitation；Common milfoil have purify the blood, diuresis, diaphoresis, improve fear of cold, hypertension, vegetative dystonie, more The effects such as term obstacle, black speck；Radix Glycyrrhizae has functions that and middle emergency, lung moistening, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription；Cortex Phellodendri and Rhizoma Coptidis It is respectively provided with heat clearing and damp drying, purging intense heat, except steaming, effect of detoxification sore treatment.The present invention passes through the rational compatibility of each raw material and special proposing Take method, make different effective active compositions produce synergistic function, greatly excite the property of medicine of effective active matter, system The plant extract with acne-removal function obtaining has oil suction oil-control, antimicrobial antiphlogistic and tissue repair effect, is embodied in: have Imitate happy pore, cleaning hair follicle, it is possible to decrease fat secretion, absorption skin oil and fat, Bergamot Mint Extract is in one；Have prevention and Dissolving acne, mitigate pigmentation, alleviate scytitiss, reduce the effect of cutaneous sensibility；There is superpower healing ability, kill Bacterium restrains wound, treats and prevents inflammation, skin sore, corse sweat pore, prevents the generation of cicatrix, has calm skin, improves sensitivity Property skin quality, effect of maintenance cicatrix；Epidermis antibacterial and hair follicle root bacillus etc. can quickly be killed, there are antibacterial and bacteriostasis.

The present invention has such advantages as with respect to prior art and effect:

(1) present invention passes through the rational compatibility of each raw material, makes different effective active compositions produce synergistic function, pole The big property of medicine exciting effective active matter, anti-acne effect is good, faster.

(2) what the present invention was obtained has the plant extract of acne-removal function from multiple gentle raw materials, joins by optimal compatibility System forms, and drug effect is gentle, has no side effect.

(3) plant extract with acne-removal function that the present invention is obtained has oil suction oil-control, antimicrobial antiphlogistic and tissue and repaiies Multiple effect.

(4) present invention adopts Different Extraction Method for different material, and the extract anti-acne composition preparing is various, has Effect composition is effectively retained.

Specific embodiment

With reference to embodiment, the present invention is described in further detail, but embodiments of the present invention not limited to this.

Embodiment 1

(1) by 15 mass parts Flos Inulaes, 6 mass parts common milfoils, 12 mass parts Radix Hamamelidis Molliss, 12 mass parts Pericarpium Granatis, 4 mass Part Radix Glycyrrhizae, 4 mass parts Cortex Phellodendris and 2 mass parts Rhizoma Coptidis are separately dried, pulverized 20 mesh sieves, obtain Flos Inulae coarse powder, common milfoil thick Powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder, Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder and Cortex Phellodendri coarse powder are carried out co₂Surpass and face Boundary's fluid extraction；Wherein, Extracting temperature is 40 DEG C, and extraction pressure is 20mpa, and extraction time is 2h, co₂Flow velocity is 15l/h, point It is 40 DEG C from temperature, separating pressure is 6mpa；Collect extract, obtain plant extract 1；

(3) plant residue after step (2) extraction is carried out co again₂Supercritical fluid extraction；Wherein, dehydrated alcohol is made For entrainer, Extracting temperature is 45 DEG C, and extractions pressure is 25mpa, and extraction time is 2h, co₂Flow velocity is 15l/h, separation temperature For 45 DEG C, separating pressure is 8mpa；Collect extract, obtain plant extract 2；

(4) plant residue after step (3) extraction is mixed with Radix Glycyrrhizae coarse powder, Rhizoma Coptidis coarse powder, after soaking 10h, 100 DEG C heating and refluxing extraction 3 times, each 1.5h, then filters, merging filtrate, filtrate concentrates, and is cooled to less than 40 DEG C；Then stirring Mix under state, add dehydrated alcohol, make ethanol content in the mixed liquor finally giving reach 70%；4 DEG C of airtight placement 12h are to precipitation Completely, remove precipitation, the supernatant decompression recycling ethanol obtaining, obtain concentrated solution, the relative density of concentrated solution is 1.20；

(5) plant extract 2 prepared to the prepared plant extract 1 of step (2), step (3) and step (4) are obtained Concentrated solution mix homogeneously, obtains the plant extract with acne-removal function.

Embodiment 2

(1) by 10 mass parts Flos Inulaes, 7 mass parts common milfoils, 10 mass parts Radix Hamamelidis Molliss, 15 mass parts Pericarpium Granatis, 3 mass Part Radix Glycyrrhizae, 5 mass parts Cortex Phellodendris and 1 mass parts Rhizoma Coptidis are separately dried, pulverized 20 mesh sieves, obtain Flos Inulae coarse powder, common milfoil thick Powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder, Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder and Cortex Phellodendri coarse powder are carried out co₂Surpass and face Boundary's fluid extraction；Wherein, Extracting temperature is 35 DEG C, and extraction pressure is 18mpa, and extraction time is 2.5h, co₂Flow velocity is 20l/h, Separation temperature is 35 DEG C, and separating pressure is 10mpa；Collect extract, obtain plant extract 1；

(3) plant residue after step (2) extraction is carried out co again₂Supercritical fluid extraction；Wherein, dehydrated alcohol is made For entrainer, 40 DEG C of Extracting temperature, extraction pressure is 20mpa, and extraction time is 2.5h, co₂Flow velocity is 20l/h, separation temperature For 40 DEG C, separating pressure is 10mpa；Collect extract, obtain plant extract 2；

(4) plant residue after step (3) extraction is mixed with Radix Glycyrrhizae coarse powder, Rhizoma Coptidis coarse powder, after soaking 6h, 80 DEG C Heating and refluxing extraction 2 times, each 2h, then filters, merging filtrate, filtrate concentrates, and is cooled to less than 40 DEG C；Then in stirring shape Under state, add dehydrated alcohol, make ethanol content in the mixed liquor finally giving reach 75%；10 DEG C of airtight placement 48h are to having precipitated Entirely, remove precipitation, the supernatant decompression recycling ethanol obtaining, obtain concentrated solution, the relative density of concentrated solution is 1.1；

Embodiment 3

(1) by 20 mass parts Flos Inulaes, 6 mass parts common milfoils, 15 mass parts Radix Hamamelidis Molliss, 8 mass parts Pericarpium Granatis, 5 mass Part Radix Glycyrrhizae, 3 mass parts Cortex Phellodendris and 3 mass parts Rhizoma Coptidis are separately dried, pulverized 10 mesh sieves, obtain Flos Inulae coarse powder, common milfoil thick Powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder, Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder and Cortex Phellodendri coarse powder are carried out co₂Surpass and face Boundary's fluid extraction；Wherein, Extracting temperature is 45 DEG C, and extraction pressure is 30mpa, and extraction time is 1h, co₂Flow velocity is 10l/h, point It is 45 DEG C from temperature, separating pressure is 5mpa；Collect extract, obtain plant extract 1；

(3) plant residue after step (2) extraction is carried out co again₂Supercritical fluid extraction；Wherein, dehydrated alcohol is made For entrainer, Extracting temperature is 50 DEG C, and extractions pressure is 30mpa, and extraction time is 1h, co₂Flow velocity is 10l/h, separation temperature For 50 DEG C, separating pressure is 5mpa；Collect extract, obtain plant extract 2；

(4) plant residue after step (3) extraction is mixed with Radix Glycyrrhizae coarse powder, Rhizoma Coptidis coarse powder, after soaking 12h, 90 DEG C heating and refluxing extraction 4 times, each 1h, then filters, merging filtrate, filtrate concentrates, and is cooled to less than 40 DEG C；Then in stirring Under state, add dehydrated alcohol, make ethanol content in the mixed liquor finally giving reach 80%；8 DEG C of airtight placement 24h are to having precipitated Entirely, remove precipitation, the supernatant decompression recycling ethanol obtaining, obtain concentrated solution, the relative density of concentrated solution is 1.25；

Comparative example 1 (no Flos Inulae and common milfoil)

(1) 12 mass parts Radix Hamamelidis Molliss, 12 mass parts Pericarpium Granatis, 4 mass parts Radix Glycyrrhizaes, 4 mass parts Cortex Phellodendris and 2 mass parts are yellow Even it is separately dried, pulverized 20 mesh sieves, obtaining Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder, Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis thick Powder；

(2) Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder and Cortex Phellodendri coarse powder are carried out co₂Supercritical fluid extraction；Wherein, extract temperature Spend for 40 DEG C, extraction pressure is 20mpa, extraction time is 2h, co₂Flow velocity is 15l/h, and separation temperature is 40 DEG C, separating pressure For 6mpa；Collect extract, obtain plant extract 1；

Comparative example 2 (no Radix Hamamelidis Molliss and Pericarpium Granati)

(1) 15 mass parts Flos Inulaes, 6 mass parts common milfoils, 4 mass parts Radix Glycyrrhizaes, 4 mass parts Cortex Phellodendris and 2 mass parts are yellow Even it is separately dried, pulverized 20 mesh sieves, obtaining Flos Inulae coarse powder, common milfoil coarse powder Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder and Cortex Phellodendri coarse powder are carried out co₂Supercritical fluid extraction；Wherein, extract temperature Spend for 40 DEG C, extraction pressure is 20mpa, extraction time is 2h, co₂Flow velocity is 15l/h, and separation temperature is 40 DEG C, separating pressure For 6mpa；Collect extract, obtain plant extract 1；

Comparative example 3 (no Radix Glycyrrhizae, Cortex Phellodendri and Rhizoma Coptidis)

(1) by 15 mass parts Flos Inulaes, 6 mass parts common milfoils, 12 mass parts Radix Hamamelidis Molliss and 12 mass parts Pericarpium Granatis respectively It is dried, pulverized 20 mesh sieves, obtain Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder powder and Pericarpium Granati coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder and Pericarpium Granati coarse powder are carried out co₂Supercritical fluid extracts Take；Wherein, Extracting temperature is 40 DEG C, and extraction pressure is 20mpa, and extraction time is 2h, co₂Flow velocity is 15l/h, and separation temperature is 40 DEG C, separating pressure is 6mpa；Collect extract, obtain plant extract 1；

(4) plant residue after step (3) extraction is soaked after 10h, 100 DEG C of heating and refluxing extraction 3 times, every time 1.5h, then filters, merging filtrate, and filtrate concentrates, and is cooled to less than 40 DEG C；Then, under stirring, add dehydrated alcohol, Ethanol content in the mixed liquor finally giving is made to reach 70%；4 DEG C of airtight placement 12h, to precipitating completely, remove precipitation, obtain is upper Clear liquid decompression recycling ethanol, obtains concentrated solution, the relative density of concentrated solution is 1.20；

Effect example

Example 1～3 and each 50g of plant extract with acne-removal function of comparative example 1～3 preparation, use Deionized water is diluted to 1000g as sample, transfers to 50 patients with acne to use, sooner or later once, and its effect of tracking and testing, knot Fruit is shown in Table 1.

Method of testing and effect standard

(1) with reference to " new Chinese medicine guideline of clinical investigations ", Evaluation of Synthetic Effect of Holistic is with skin lesion degree, skin lesion distribution, disease Shape, the total mark of sign calculate curative effect rate.Skin lesion before curative effect=(after skin lesion counts-treats before treatment, skin lesion counts)/treatment Count * 100%.Cure: skin lesion disappears more than 90%, only a little pigmentation；Effective: skin lesion disappears 60%～90%, disease Shape mitigates；Effective: skin lesion disappears 20%～60%, symptom is improved；Invalid: skin lesion disappears, and < 20%, clinical symptoms are not improved.Always Effective percentage=cure rate+obvious effective rate+effective percentage.

(2) fat secretion decrement test: detected respectively using before product and little using product 24 with oils and fatss measuring instrument Shi Hou, skin surface fat content, calculate the decrement of skin surface fat content, average.

(3) lasting fat secretion decrement: continuously use product 1 week, contained with oils and fatss measuring instrument detection skin surface oils and fatss Amount, disables product, after waiting 28 days, then detects skin surface fat content, calculates the lasting fat secretion decrement of skin, makes even Average.

(4) cure the time of acne: using product, see and look into the time used by healing, average.

Table 1 has the plant extract acne-removing evaluation of acne-removal function

Application Example

Take 5% (w/w) respectively has the plant extract of acne-removal function, the glycerol of 15% (w/w), 10% (w/w) Sorbitol olein, the purified water of 65% (w/w) make acne-eliminating cosmetic emulsion.

This emulsion has oil suction oil-control, antimicrobial antiphlogistic and tissue repair effect.

Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not subject to above-described embodiment Limit, other any spirit without departing from the present invention and the change made under principle, modification, replacement, combine, simplify, All should be equivalent substitute mode, be included within protection scope of the present invention.

Claims

1. a kind of plant extract with acne-removal function is it is characterised in that be prepared into by following raw material components in parts by mass Arrive:

2. the plant extract with acne-removal function according to claim 1 it is characterised in that by following in parts by mass Raw material components prepare:

3. the preparation method of the plant extract with acne-removal function described in claim 1 or 2 is it is characterised in that comprise as follows Step:

(1) Flos Inulae, common milfoil, Radix Hamamelidis Molliss, Pericarpium Granati, Radix Glycyrrhizae, Cortex Phellodendri and Rhizoma Coptidis are separately dried, pulverize and sieve, obtain gold Small cup flower coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder, Radix Glycyrrhizae coarse powder, Cortex Phellodendri coarse powder and Rhizoma Coptidis coarse powder；

(2) Flos Inulae coarse powder, common milfoil coarse powder, Radix Hamamelidis Molliss coarse powder, Pericarpium Granati coarse powder and Cortex Phellodendri coarse powder are carried out co₂Shooting flow Body extracts；Wherein, Extracting temperature is 35～45 DEG C, and extraction pressure is 18～30mpa, and extraction time is 1～2.5h, co₂Flow velocity For 10～20l/h, separation temperature is 35～45 DEG C, and separating pressure is 5～10mpa；Collect extract, obtain plant extract 1；

(3) plant residue after step (2) extraction is carried out co again₂Supercritical fluid extraction；Wherein, dehydrated alcohol is as folder Band agent, Extracting temperature is 40～50 DEG C, and extraction pressure is 20～30mpa, and extraction time is 1～2.5h, co₂Flow velocity be 10～ 20l/h, separation temperature is 40～50 DEG C, and separating pressure is 5～10mpa；Collect extract, obtain plant extract 2；

(4) plant residue after step (3) extraction is mixed with Radix Glycyrrhizae coarse powder, Rhizoma Coptidis coarse powder, after soaking 6～12h, 80～ 100 DEG C of heating and refluxing extraction 2～4 times, 1～2h every time, then filters, merging filtrate, filtrate concentrates, cooling；Then in stirring Under state, add dehydrated alcohol, make ethanol content in the mixed liquor finally giving reach 70～80%；Airtight place to having precipitated Entirely, remove precipitation, the supernatant decompression recycling ethanol obtaining, obtain concentrated solution；

(5) concentration that plant extract 2 prepared to the prepared plant extract 1 of step (2), step (3) and step (4) are obtained Liquid mix homogeneously, obtains the plant extract with acne-removal function.

4. the plant extract with acne-removal function according to claim 3 preparation method it is characterised in that:

Co described in step (2)₂The condition of supercritical fluid extraction is: Extracting temperature is 40 DEG C, and extraction pressure is 20mpa, carries The time is taken to be 2h, co₂Flow velocity is 15l/h, 40 DEG C of separation temperature, and separating pressure is 6mpa.

5. the plant extract with acne-removal function according to claim 3 preparation method it is characterised in that:

Co described in step (3)₂The condition of supercritical fluid extraction is: Extracting temperature is 45 DEG C, and extraction pressure is 25mpa, carries The time is taken to be 2h, co₂Flow velocity is 15l/h, 45 DEG C of separation temperature, and separating pressure is 8mpa.

6. the plant extract with acne-removal function according to claim 3 preparation method it is characterised in that:

The condition of the heating and refluxing extraction described in step (4) is: 100 DEG C of heating and refluxing extraction 3 times, each 1.5h.

7. the plant extract with acne-removal function according to claim 3 preparation method it is characterised in that:

The condition of the airtight placement described in step (4) is 4～10 DEG C of placement 12～48h.

8. the plant extract with acne-removal function according to claim 3 preparation method it is characterised in that:

The relative density of the concentrated solution described in step (4) is 1.1～1.25.

9. described in claim 1 or 2, there is the application in skin care field of the plant extract of acne-removal function.

10. application in skin care field for the plant extract with acne-removal function according to claim 9, its feature It is:

The dosage form of described skin care item is solution, suspension, emulsion, cream, paste, gel, milk, skin care liquid, powder, perfume (or spice) Soap, oil, dry powder, foundation emulsion, wet-milling or spray.