CN106310082A - 一种补肾中药组合物及其制备方法 - Google Patents
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- WTARULDDTDQWMU-UHFFFAOYSA-N β-pinene Chemical compound C1C2C(C)(C)C1CCC2=C WTARULDDTDQWMU-UHFFFAOYSA-N 0.000 description 1
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Abstract
本发明公开一种补肾中药组合物及其制备方法。本中药组合物,以重量份数计:包括淫羊藿38~42份、生地28~32份、益智仁18~22份、当归13~17份、黄芪13~17份、熟地黄13~17份、五味子10~14份、仙茅10~14份、菟丝子10~14份、女贞子10~14份、补骨脂10~14份、复盆子10~14份、金樱子10~14份、桑寄生10~14份、山枝8~12份、黄柏8~12份、苦参8~12份、黄连8~12份、甘草8~12份。本发明的有益效果在于,采用上述的配方及方法制备所得到的补肾中药组合物,对肾脏及肾经的气血循环,或功能与肾产生关联的器官组织,如相关泌尿、生殖系统等进行调理,补肾见效快,对人体无毒副作用,治疗效果好。
Description
技术领域
本发明涉及一种中药组合物,属于中医药领域,具体的说是一种补肾中药组合物及其制备方法。
背景技术
中医认为肾位于腰部,脊柱之两侧,左右各一。肾脏的主要生理功能是藏精、主水、主纳气、主生殖,主骨生髓,开窍于耳,其华在发。肾脏由于肾藏有先天之精,为脏腑阴阳之本,也是人体生长、发育、生殖之源,是生命活动之根本,故中医相对于脾胃为后天之本而称为肾为“先天之本”;肾中藏有元阴元阳,元阴属水,元阳属火,故肾又称为“水火之脏”。
祖国医学认为,肾藏精主骨,腰为肾之府;肝藏血主筋。肾虚精亏则腰膝酸软,神疲乏力;肾虚不固则遗精尿频;肝虚血少无以濡养筋脉,则筋骨痿弱;肝肾精血亏虚,易受风寒湿邪侵袭,引致风湿痹痛反复发作,日久难愈。
上述症状,常可见于西医诊断为风湿性关节炎、腰腿痛、腰肌劳损、神经官能症等多种疾病中,在临床上极为常见。
肾虚经确诊后及时正规有效的治疗是很关键的,肾虚多为积累成疾,切不可以用急于求成而用大补之药进补,而应慢慢调理。补肾药膳是选用补肾气、温肾阳、滋肾阴的中药,配合一定食物,经烹调而成的药膳食品。它具有温肾壮阳、填精生髓之功效,适用于肾虚证。需要注意的是药膳不能代替药物治疗,因此需要研发一种补肾见效快且对身体无毒副作用的中药组合物。
发明内容
本发明提出一种补肾中药组合物,具有补肾阳、滋肾阴、治疗腰椎疾病的作用。
为实现上述目的,本发明所述一种补肾中药组合物,实现步骤如下:以下原料以重量份数计:淫羊藿38~42份、生地28~32份、益智仁18~22份、当归13~17份、黄芪13~17份、熟地黄13~17份、五味子10~14份、仙茅10~14份、菟丝子10~14份、女贞子10~14份、补骨脂10~14份、复盆子10~14份、金樱子10~14份、桑寄生10~14份、山枝8~12份、黄柏8~12份、苦参8~12份、黄连8~12份、甘草8~12份。
优选的,所述一种补肾中药组合物,以下原料以重量份数计:淫羊藿40份、生地30份、益智仁20份、当归15份、黄芪15份、熟地黄15份、五味子12份、仙茅12份、菟丝子12份、女贞子12份、补骨脂12份、复盆子12份、金樱子12份、桑寄生12份、山枝10份、黄柏10份、苦参10份、黄连10份、甘草10份。
所述中药组合物的剂型为片剂、丸剂、散剂、胶囊剂、口服液。
本发明所述一种补肾中药组合物的制备方法,实现步骤如下:
(1)先将淫羊藿、生地、益智仁、当归、黄芪、熟地黄、五味子、仙茅、菟丝子、女贞子、补骨脂、复盆子、金樱子、桑寄生、山枝、黄柏、苦参、黄连、甘草按照比例称重后磨粉;
(2)将水和蜂蜜以重量份数计,按照水和蜂蜜1:10的比例调配后,用文火熬20~30min后冷却至18~22℃待用;
(3)将药粉和熬好的蜂蜜以重量份数计,按1:1.1的比例调配并搅拌均匀,待用;
(4)将上述调配并搅拌均匀的混合物静置1~2h,制粒6~9g/粒。
所述磨粉粒径为300~500目。
所述蜂蜜为荆条蜜、紫苜蓿蜜、乌桕蜜中的一种或几种蜜的任意组合。
所述蜂蜜的波美度为40度,含水量为25%
所述淫羊藿,又称三枝九叶草,具有兴奋性机能、降血压、抗病毒的功效。
所述生地,别名生地黄;含地黄素、梓醇、多种氨基酸等。具有强心、利尿、解热之功效。
所述益智仁具有温脾止泻摄涎,暖肾缩尿固精之功效。
所述当归含β-蒎烯、α-蒎烯、莰烯等中性油有机酸、糖类、维生素、氨基酸等;具有补血和血,用于血虚,面色萎黄,眩晕心悸等功效。
所述黄芪有增强机体免疫功能、保肝、利尿、抗衰老、抗应激、降压和较广泛的抗菌作用。
所述熟地黄甘、微苦、微温,归心、肝、肾经。功用:补血调经,滋阴补肾。熟地黄是生地黄用黄酒拌闷,晒蒸制得,多用于养血补肾。
所述五味子《本经》记载,“主益气,补不足,强阴,益男子精”。
所述仙茅温肾阳壮、祛除寒湿。
所述菟丝子补肝肾、强筋骨、壮肾阳,以及为治腰痛之主药。
所述女贞子用于补肝肾阴、强筋骨,药力平和。
所述补骨脂含补骨脂乙素,为天然查耳酮;又含多种香豆精类物质,主要为补骨脂内酯和异补骨脂内酯。
所述复盆子含维生素A类物质、维生素C、挥发油等,具有补益肝肾之功效。
所述金樱子含柠檬酸、苹果酸,鞣质、树脂、维生素C、皂甙、糖类,具有固精缩尿,固崩止带,涩肠止泻之功效。
所述桑寄生含广寄生甙(即篇蓄甙)、槲皮甙,具补肝肾、强筋骨,滋补肾阴之功效。
所述山枝,即山枝根为海桐花科植物光叶海桐的根或根皮,具有补肺肾、祛风湿、活血通络等功效。
所述黄柏清热,燥湿,泻火,解毒。
所述苦参在《本草纲目》中记载:“苦参、黄柏之苦寒,皆能补肾,盖取其苦燥湿,寒除热”。
所述黄连主要含小檗碱等大量生物碱,清热燥湿,泻火解毒之功效。
所述甘草含有甘草酸、甘草甙、甘草甙、甘草素、甘草醇、7-甲基香豆精、伞形花内酯等,用于心气虚,脾胃气虚,倦怠乏力,以及用于调和某些药物的烈性。
所述荆条蜜、紫苜蓿蜜、乌桕蜜益气补中、发汗散热、散寒清目。适合气血不足、伤风头痛、失眠者,能增强人体特异性和非特异性免疫功能,提高体质,对心血管系统疾病,如强心、改善血液循环方面有辅助疗效,具有补虚之功效。
所述中药组合物的剂型为:片剂、丸剂、散剂、胶囊剂、口服液。
所述中药组合物方中以菟丝子补肝肾、强筋骨、壮肾阳,治腰痛为主药;女贞子、桑寄生补肝肾、强筋骨,滋补肾阴;金樱子固精摄尿,使精关固而精髓内养以为其辅;肾虚则风湿之邪易于侵袭,血脉不利,故配山枝、当归养血活血,消瘀滞,舒筋通络;补骨脂强筋骨,苦参、仙茅祛风湿以为佐使;诸药相伍,具有养血、活血、健骨、补肾之功效,达到治疗阴阳亏损,头晕耳鸣,腰膝酸软、神困体倦、盗汗、自汗、畏寒、肢冷、遗精、小便短赤、尿频、尿失禁、二便不通及老年性前列腺炎、肾炎、不侵、神经衰弱、腰间盘突出等症。
本发明所述一种补肾中药组合物及其制备方法,其有益效果在于:采用上述的配方及方法制备所得到的补肾中药组合物,以现代人的身体素质为中心、发病原为根本、靶病灶为目标,研制出纯中药复配物,对肾脏及肾经的气血循环,脏器功能与关联器官进行调理,补肾见效快,对人体无毒副作用,治疗效果好,而且具有治疗腰椎疾病的作用。
具体实施方式
实施例1
一种补肾中药组合物的制备方法,实现步骤如下:
(1)以下原料以重量份数计:淫羊藿40份、生地30份、益智仁20份、当归15份、黄芪15份、熟地黄15份、五味子12份、仙茅12份、菟丝子12份、女贞子12份、补骨脂12份、复盆子12份、金樱子12份、桑寄生12份、山枝10份、黄柏10份、苦参10份、黄连10份、甘草10份,按照比例称重后磨粉,磨粉粒径为300目;
(2)将水和荆条蜜以重量份数计,按照水和蜂蜜1:10的比例调配后,用文火熬30min后冷却至18℃待用;
(3)将药粉和熬好的蜂蜜以重量份数计,按1:1.1的比例调配并搅拌均匀,待用;
(4)将上述调配并搅拌均匀的混合物静置1~2h,制粒6~9g/粒;
(5)三剂为一疗程,连续服用三个疗程,150名志愿者中均为肾虚患者,其中有146人肾虚问题得到明显改善,有效率为97.3%,证明本发明的中药组合物效果好。
临床使用
临床上症见肾亏腰痛,膝软无力,不耐久坐,头昏耳鸣,疲乏烦躁,健忘,小便频数,遗精梦泄,风湿骨痛,神经衰弱,舌苔薄白,脉沉细,两尺表现无力者,均可服用壮腰健肾丸。水蜜丸一次3.5克;大蜜丸一次一丸,一日2-3次,4周一个疗程。
本产品具有补肾阳、滋肾阴双向调节作用,兼具治疗与保健双功效。具有明显的抗氧化、防衰老作用。
临床研究
本产品是以名老中医的经验方为基础的中药制剂,在长期临床应用中深受用户的信赖。先后经本人临床试验,既有补肾作用又有降火作用,既有活血养血又有健骨补肾的作用,特别是针对夜尿多,遗精梦泄,阳痿,神疲乏力等,治疗效果显著。使用过程中,未见明显毒副作用。附典型病例:
病例一:李XX,男,42岁。腰痛,尿频,尿急多年,经常感到疲乏,食欲差,面色苍白。诊断为腰肌劳损。经服用壮腰健肾丸15天后,腰痛及尿频急消失,疲乏感咸轻,面色好转,血常规检查,血红蛋白由原来的10g上升为12g。
病例二:王XX,男,27岁,干部。因失眠、头昏、心慌一月多,每晚遗精一次,腰酸疲乏,食欲欠佳,诊断为神经衰弱。服用壮腰健肾丸10天后,头昏消失,睡眠好转,疲乏减轻,食欲增加,遗精次数减少。共服药30天,诸症消失。
病例三:刘XX,男,23岁,工兵。每周遗精3-4次,腰酸痛,疲乏已半年多。经服用壮腰健肾丸10天后,遗精明显减少,10天中仅3次,睡眠好,食欲、精神俱转佳。为巩固疗效,再给药十天。
病例四:周XX,男,42岁,工人。腰痛,经常感到疲乏,尿频,食欲差。诊断为神经衰弱。服用桂花蜜调制壮腰健肾丸30天后,头昏消失,睡眠好转,疲乏减轻,食欲增加。共服药60天,诸症消失。
病例五:陈XX,女,38岁,家庭妇女。经常感到疲乏,腰痛,食欲差。诊断为神经衰弱。服用桂花蜜调制壮腰健肾丸30天后,头昏消失,睡眠好转,疲乏减轻,食欲增加。共服药60天,诸症消失。
病例六:赵XX,男,36岁,工人。尿频,食欲差,腰酸痛,疲乏。服用桂花蜜调制壮腰健肾丸30天后,头昏消失,睡眠好转,疲乏减轻,食欲增加。共服药60天,诸症消失。
综上本方中的蜂蜜选择在方剂中起到一定治疗效果。
Claims (7)
1.一种补肾中药组合物,其特征在于:以下原料以重量份数计:淫羊藿38~42份、生地28~32份、益智仁18~22份、当归13~17份、黄芪13~17份、熟地黄13~17份、五味子10~14份、仙茅10~14份、菟丝子10~14份、女贞子10~14份、补骨脂10~14份、复盆子10~14份、金樱子10~14份、桑寄生10~14份、山枝8~12份、黄柏8~12份、苦参8~12份、黄连8~12份、甘草8~12份。
2.如权利要求1所述一种补肾中药组合物,其特征在于:以下原料以重量份数计:淫羊藿40份、生地30份、益智仁20份、当归15份、黄芪15份、熟地黄15份、五味子12份、仙茅12份、菟丝子12份、女贞子12份、补骨脂12份、复盆子12份、金樱子12份、桑寄生12份、山枝10份、黄柏10份、苦参10份、黄连10份、甘草10份。
3.如权利要求1所述一种补肾中药组合物,其特征在于:所述中药组合物的剂型为片剂、丸剂、散剂、胶囊剂、口服液。
4.如权利要求1所述的一种补肾中药组合物的制备方法,其特征在于:
(1)先将淫羊藿、生地、益智仁、当归、黄芪、熟地黄、五味子、仙茅、菟丝子、女贞子、补骨脂、复盆子、金樱子、桑寄生、山枝、黄柏、苦参、黄连、甘草按照比例称重后磨粉;
(2)将水和蜂蜜以重量份数计,按照水和蜂蜜1:10的比例调配后,用文火熬20~30min后冷却至18~22℃待用;
(3)将药粉和熬好的蜂蜜以重量份数计,按1:1.1的比例调配并搅拌均匀,待用;
(4)将上述调配并搅拌均匀的混合物静置1~2h,制粒6~9g/粒。
5.如权利要求4所述的一种补肾中药组合物的制备方法,其特征在于:所述磨粉粒径为300~500目。
6.如权利要求4所述的一种补肾中药组合物的制备方法,其特征在于:所述蜂蜜为荆条蜜、紫苜蓿蜜、乌桕蜜中的一种或几种蜜的任意组合。
7.如权利要求6所述的一种补肾中药组合物的制备方法,其特征在于:所述蜂蜜的波美度为40度,含水量为25%。
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