CN106137194A - A kind of self adaptation pressure fat pulse parameter system of selection and device - Google Patents
A kind of self adaptation pressure fat pulse parameter system of selection and device Download PDFInfo
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- CN106137194A CN106137194A CN201510137501.9A CN201510137501A CN106137194A CN 106137194 A CN106137194 A CN 106137194A CN 201510137501 A CN201510137501 A CN 201510137501A CN 106137194 A CN106137194 A CN 106137194A
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Abstract
A kind of self adaptation pressure fat pulse parameter system of selection, including: prescan gathers target area signal under the pressure fat impulse action of different parameters, described signal is carried out spectrum distribution calculating, carry out water signal intensity and fat signal Strength co-mputation again, then it is estimated comparing to each group of lower the obtained signal strength data of parameter role according to the assessment formula of systemic presupposition, assessment result is designated as R, the pressure fat pulse parameter that one group of pressure fat pulse parameter corresponding to largest r value will be set in clinical scanning.The self adaptation pressure fat pulse parameter system of selection of the present invention can determine optimal pressure fat pulse parameter according to Current Scan case, has good universality, the pressure fat effect being greatly improved in magnetic resonance scan sequences.
Description
Technical field
The present invention relates to mr imaging technique field, particularly relate to a kind of true for magnetic resonance imaging parameter
Fixed method and device.
Background technology
Fat-suppression technique in magnetic resonance clinical imaging, i.e. presses fat, is to utilize narrow frequency pulse independent excitation
Fat signal, and after the fat signal after utilizing gradient strength to excite is broken up, then perform the one-tenth of routine
As sequence, due to fat signal by dephasing in advance, will detect not in conventional imaging sequential sampling
To fat signal, because of referred to herein as " fat suppression ".
Pressure fat technology, is (to differ about under 1.5T field intensity based on having different resonant frequencies between water fat
Physical phenomenon 200Hz), works as B0Ratio is time more uniform, the distribution on frequency spectrum of water signal and fat signal
All compare concentration, as it is shown on figure 3, near water signal integrated distribution frequency of heart 200Hz in systems, spectral peak
Halfwidth the most about 100Hz, at this point it is possible to select bandwidth about 100Hz, frequency-selecting at the narrow-band impulse of-200Hz,
Fat signal is excited and does not affect water signal (exciting scope as shown in square frame 31 in Fig. 3), then by square frame
The signal excited in 31 is broken up, and so just can't detect the fat signal in square frame 31 in follow-up imaging.
It follows that the quality of pressure fat effect, in depending on square frame 1, excite the setting of scope, i.e. pressure fat pulse ginseng
Number, such as the setting of bandwidth, frequency offset, flip angle etc., when square frame 31 scope is the least, or position has partially
Difference, then will break up less fat signal, and cause the fatty residual volume after imaging too many；When square frame 31 model
Enclose too big, or during deflection water peak, position, then part water signal also broken up while breaing up fat signal,
The normal water signal intensity after imaging is caused to decline so that signal noise ratio (snr) of image is on the low side.
In existing clinical imaging, commonly used pressure fat technology, is all by experimental technique, in advance
Selected one group of parameter being attained by as a rule preferably pressing fat effect, by this parameter in the product
Just immobilize after arranging, or the pressure fat pulse parameter that default many groups are fixed be for different scanning scene,
When scan protocols is arranged, select different parameters according to recommendation.But, when clinical imaging, no
Same patient, different scanning positions, all can cause the spectral peak distribution of water signal and fat signal to become
Changing, simply use the parameter that a group or array are fixing, universality is poor, it is difficult to meet all scanning scenes
Under pressure fat demand.
Therefore, in order to adapt to the different scanning position of different patient, it is necessary to provide the one can be automatically according to
Concrete scanning scene and individual patients situation and the method and device of pressure fat pulse parameter when setting scanning.
Summary of the invention
To be solved by this invention is to press fat pulse parameter to be magnetic resonance product in prior art to issue front solid
Fixed a group or several groups of parameters in system, the most limited range of choice universality is poor, sweeps in difference
Retouch scene or for during different patient due to the limitation selected, the pressure fat pulse parameter often used is also
It not optimal setting, thus the problem affecting final pressure fat uniformity.
For solving the problems referred to above, the present invention provides a kind of self adaptation pressure fat pulse parameter system of selection, including:
Prescan, gathers target area signal under the pressure fat impulse action of different parameters；
Calculate the spectrum distribution of described signal；
Calculate water signal intensity SwWith fat signal strength Sf；
Assess the effect of each group of pressure fat pulse, calculate water signal intensity S by the assessment formula of systemic presuppositionw
And/or fat signal strength SfNumerical relation R；
By the pressure fat pulse parameter that one group of parameter apolegamy is clinical scanning corresponding to maximum numerical relation R.
Optionally, described assessment formula is:
R=Sw/Sf
Optionally, described assessment formula is:
R=Sw 2/Sf
Optionally, described assessment formula is:
R=1/Sf
Optionally, by taking amplitude acquisition spectrum distribution after described signal is carried out Fourier transformation.
Optionally, the scanning sequence that described prescan uses is by pressing fat module and regioselectivity sequence to form.
Optionally, the scanning sequence that described prescan uses is by pressing fat module and STEAM sequence to form.
Optionally, the scanning sequence that described prescan uses is by pressing fat module and PRESS sequence to form.
For solving above-mentioned technical problem, the present invention also provides for a kind of self adaptation pressure fat pulse parameter and selects device,
Including:
Pre-scan module, for gathering target area signal under the pressure fat impulse action of different parameters；
Spectrum distribution computing module, for calculating the spectrum distribution of described signal；
Signal intensity calculates module, is used for calculating water and/or fat signal intensity；
Evaluation module, for calculating water signal intensity and/or fat signal intensity according to the assessment formula preset
Numerical relation R, determine optimal pressure fat parameter according to calculating.
Optionally, described signal intensity calculating module includes that water signal intensity calculates module and fat signal is strong
Degree computing module.
Compared with prior art, the present invention provide self adaptation pressure fat pulse parameter system of selection, be not
Magnetic resonance product fixes one group or several groups pressure fat pulse parameter in systems before issuing, but sets in systems
The system of selection of a fixed pressure fat pulse parameter and device, the method is short for passing through before patient starts scanning
The pre-scan calibration of time, finds one group of parameter for Current Scan case pressure fat best results, as
The parameter that clinical pressure fat image scanning is used carries out follow up scan.The method can be embedded in nuclear magnetic resonance
Calibration phase in, increase patient's review time with little need for extra, and can be according to the tool of current patents
Body demand determines optimal pressure fat pulse parameter, has good universality, is greatly improved magnetic resonance imaging mistake
Pressure fat effect in journey.
Accompanying drawing explanation
Fig. 1 is that the present invention presses fat pulse parameter system of selection flow chart；
Fig. 2 is prescan sequence timing diagram in the embodiment of the present invention one；
Fig. 3 is water fat spectrum distribution schematic diagram；
Fig. 4 is R value situation of change schematic diagram under different parameters in the embodiment of the present invention one；
Fig. 5 is to use pressure fat pulse parameter fixing in advance in prior art and use self adaptation pressure of the present invention
The pressure fat effect contrast figure of fat pulse parameter；
Fig. 6 is that self adaptation of the present invention pressure fat pulse parameter selects installation drawing；
Fig. 7 is that signal intensity of the present invention calculates module diagram.
Detailed description of the invention
Understandable, below in conjunction with the accompanying drawings for enabling the above-mentioned purpose of the present invention, feature and advantage to become apparent from
With embodiment, the detailed description of the invention of the present invention is described in detail.Obviously, described embodiment is only
It it is the part of the embodiment of the present invention rather than they are whole.According to these embodiments, this area
Those of ordinary skill obtainable other embodiments all on the premise of without creative work, all
Belong to protection scope of the present invention.
In the most commonly used existing pressure fat technology, it is all the method by experiment, Yu Xianxuanding
One group of parameter being attained by as a rule preferably pressing fat effect, is then published to magnetic resonance product
In, the most fixing no longer change of this parameter.Or, there is several groups of fixing pressure fat pulse parameters, energy
Enough adapt to different scanning scenes respectively, when agreement is arranged, can be selected for different parameters according to recommendation.
But generally speaking, these methods are all to use fixing pressure fat pulse parameter, and universality is poor, can not keep away
There is inapplicable scene in the meeting exempted from, and the matching degree for concrete scanning case is the most not high enough, pressure fat effect
Fruit is the most not ideal.
As it is shown in figure 1, the present invention proposes a kind of self adaptation for different scanning case presses fat pulse choosing
Access method, comprises the steps:
S01: prescan, gathers target area signal under the pressure fat impulse action of different parameters；
S02: signal calculated spectrum distribution, after carrying out Fourier transformation to the signal collected in S01 step
Take amplitude, it is thus achieved that the signal spectrum distribution after the intrinsic pressure fat in target area；
S03: calculate water signal intensity SwWith fat signal strength Sf, described water signal intensity SwCalculating lead to
Cross and choose certain bandwidth near water peak in the frequency spectrum profile obtained in S02 and carry out signal integration acquisition,
Described fat signal strength SfCalculate by S02 obtain frequency spectrum profile on fat peak near select
Take certain bandwidth and carry out signal integration acquisition；
S04: assess the effect of each group of pressure fat pulse, according to the assessment formula preset in system respectively to each group
Pressure fat pulse parameter scanning the data obtained is estimated computing, and it is the biggest that acquired results is designated as R, R value, presses fat
Effect is the best；
S05: one group of maximum for R value in S04 step pressure fat pulse parameter is matched automatically as sweep phase
Pressure fat pulse parameter.
Embodiment one
The pressure fat pulse parameter selection course of the present embodiment performs at the calibration phase of magnetic resonance imaging.At this
In embodiment, when performing S01 prescan step, prescan sequence is by pressing fat module 1 (described pressure fat module
1 is made up of the frequency selectivity excitation pulse and dephasing gradient selecting layer) and stimulated echo acquisition sequence
(Stimulated echo acquisition mode is called for short STEAM sequence) 2 compositions, sequential chart is such as
Shown in Fig. 2, although it should be noted that only with by described pressure fat module 1 and STEAM sequence in the present invention
The sequence of row 2 composition illustrates as the sequence of prescan in S01 step, but this sequence is not to use
In limiting the scope of the invention, those skilled in the art should be readily apparent that and carry out the pre-of S01 step
Scanning sequence can also is that by pressure fat module and other acquisition sequence with regioselectivity form, as by
Pressure fat module and point differentiate spectrum positioning sequence, and (Point-resolved spectroscopy is called for short PRESS
Sequence) composition.Using frequency offset as the adjustable parameter of pressure fat pulse, bandwidth, flip angle etc. will be excited
Other pressure fat pulse parameters are set to preset parameter, the frequency offset that given many groups are different, gather different frequency
Signal under Pian Zhi, with a width of 200Hz of excitation band in the present embodiment, flip angle is 95 °, gathers 7 groups
Signal under different frequency biasing (-40Hz ,-20Hz, 0Hz, 20Hz, 40Hz, 60Hz, 80Hz) enters
Row explanation, practical operation according to specifically scanning the quantity of requirements set collection and can excite bandwidth and flip angle
Isoparametric concrete numerical value.
It is pointed out that in this embodiment, the pressure fat module of clinical scanning sequence excite bandwidth and turning over
Corner is consistent with the parameter that calibration phase uses.
After having performed the pre-scanning process of S01 step, perform S02 step, calculate signal collected frequency
Spectral structure.Take amplitude after the 7 groups of signals collected in S01 step are carried out Fourier transformation, obtain it
Spectrum distribution, as shown in Figure 3.Assume that current system mid frequency is calibrated, then the radio frequency letter of sampling
After number being modulated demodulation, Qi Shui peak 3 will 0 hertz (Hz) of alignment, fat peak 4 is distributed near-200Hz.
After obtaining described signal spectrum scattergram by S02 step, perform S03 step, to 7 groups of signals
Near water peak 3, choose certain bandwidth respectively carry out signal integration, as water signal intensity Sw, this enforcement
The bandwidth choosing 100Hz in example carries out signal integration；Near fat peak 4, also choose certain bandwidth carry out letter
Number integration, as fat signal strength Sf, the bandwidth choosing 100Hz in the present embodiment carries out signal integration.
Obtain 7 groups of data respective water signal intensity SwWith fat signal strength SfAfter, perform S04 step,
Each group of data are substituted into the assessment formula R=S of systemic presuppositionw/SfIn, it is thus achieved that 7 R values, 7 R values
Situation of change as shown in Figure 4, figure 4, it is seen that when frequency offset is 40Hz, R value is maximum, i.e.
Pressure fat effect is best, then system chooses the pressure fat pulse parameter that this group parameter is used as clinic automatically.
The left-half of Fig. 5 be prior art uses pressure fat pulse parameter fixing in advance pressure fat design sketch,
Fig. 5 right half part is the pressure that the pressure fat pulse parameter using the adaptive method of the present invention to obtain is scanned
Fat design sketch, position shown in square frame in the picture of the left and right sides is it can be seen that use the mode of the present invention to obtain
The pressure fat effect obtained is substantially better than method of the prior art.
It should be noted that the adjustable parameter of the pressure fat pulse of pre-scanning process is that frequency is inclined in the present embodiment
Put, excite bandwidth, flip angle etc. for preset parameter, but the most also can by excite bandwidth or
Flip angle or other parameters are adjustable parameter, and remaining performs prescan, set-up mode and behaviour for preset parameter
Making process identical with foregoing, here is omitted.
It should be noted that the self adaptation pressure fat pulse parameter in above example determines that process can not also
Perform at calibration phase, and be built-in in clinical pressure fat imaging sequence, i.e. perform pressure fat module 1 it
Before, first carrying out pressure fat calibration module, ibid, here is omitted for follow-up calculating evaluation process, it is thus achieved that
By feedback mechanism after assessment result, self-adaptative adjustment pressure the used parameter of fat module 1 carries out follow up scan.
Embodiment two
Performing S01 prescan, prescan sequence, by pressing fat module 1 and STEAM sequence 2 to form, needs
Illustrate, although only with the sequence being made up of described pressure fat module 1 and STEAM sequence 2 in the present embodiment
Row illustrate as the sequence of prescan in S01 step, but this sequence is not intended to limit the invention
Protection domain, those skilled in the art should be readily apparent that the prescan sequence carrying out S01 step also may be used
To be made up of pressure fat module and other acquisition sequence with regioselectivity, such as pressure fat module and PRESS
Sequence.Using frequency offset as the adjustable parameter of pressure fat pulse, other pressures such as bandwidth, flip angle will be excited
Fat pulse parameter is set to preset parameter, the frequency offset that given many groups are different, gathers under different frequency biasing
Signal, with a width of 200Hz of excitation band in the present embodiment, flip angle is 95 °, gathers 7 groups of differences frequency
Signal under rate biasing (-40Hz ,-20Hz, 0Hz, 20Hz, 40Hz, 60Hz, 80Hz) illustrates,
Practical operation according to specifically scanning the quantity of requirements set collection and can excite bandwidth and flip angle isoparametric
Concrete numerical value.
It is pointed out that in this embodiment, the pressure fat module of clinical scanning sequence excite bandwidth and turning over
Corner is consistent with the parameter that calibration phase uses.
After having performed the pre-scanning process of S01 step, perform S02 step, calculate signal collected frequency
Spectral structure.Take amplitude after the 7 groups of signals collected in S01 step are carried out Fourier transformation, obtain it
Spectrum distribution, as shown in Figure 3.Assume that current system mid frequency is calibrated, then the radio frequency letter of sampling
After number being modulated demodulation, Qi Shui peak 3 will 0 hertz (Hz) of alignment, fat peak 4 is distributed near-200Hz.
After obtaining described signal spectrum scattergram by S02 step, perform S03 step, to 7 groups of signals
Near water peak 3, choose certain bandwidth respectively carry out signal integration, as water signal intensity Sw, this enforcement
The bandwidth choosing 100Hz in example carries out signal integration；Near fat peak 4, also choose certain bandwidth carry out letter
Number integration, as fat signal strength Sf, the bandwidth choosing 100Hz in the present embodiment carries out signal integration.
Obtain 7 groups of data respective water signal intensity SwWith fat signal strength SfAfter, perform S04 step,
Each group of data are substituted into the assessment formula R=S of systemic presuppositionw 2/SfIn, it is thus achieved that 7 R values, the biggest representative of R
Pressure fat effect is the best, and that group parameter that system is chosen corresponding to the R value of maximum automatically is used as clinic
Pressure fat pulse parameter.
It should be noted that the adjustable parameter of the pressure fat pulse of pre-scanning process is that frequency is inclined in the present embodiment
Put, excite bandwidth, flip angle etc. for preset parameter, but the most also can by excite bandwidth or
Flip angle or other parameters are adjustable parameter, and remaining performs prescan, set-up mode and behaviour for preset parameter
Making process identical with foregoing, here is omitted.
Embodiment three
Performing S01 prescan, prescan sequence, by pressing fat module 1 and STEAM sequence 2 to form, needs
Illustrate, although only with the sequence being made up of described pressure fat module 1 and STEAM sequence 2 in the present invention
Illustrate as the sequence of prescan in S01 step, but what this sequence was not intended to limit the invention
Protection domain, those skilled in the art should be readily apparent that the prescan sequence carrying out S01 step is all right
It is made up of pressure fat module and other acquisition sequence with regioselectivity, such as pressure fat module and PRESS
Sequence.Using frequency offset as the adjustable parameter of pressure fat pulse, other pressures such as bandwidth, flip angle will be excited
Fat pulse parameter is set to preset parameter, the frequency offset that given many groups are different, gathers under different frequency biasing
Signal, with a width of 200Hz of excitation band in the present embodiment, flip angle is 95 °, gathers 7 groups of differences frequency
Signal under rate biasing (-40Hz ,-20Hz, 0Hz, 20Hz, 40Hz, 60Hz, 80Hz) illustrates,
Practical operation according to specifically scanning the quantity of requirements set collection and can excite bandwidth and flip angle isoparametric
Concrete numerical value.
It is pointed out that in this embodiment, the pressure fat module of clinical scanning sequence excite bandwidth and turning over
Corner is consistent with the parameter that calibration phase uses.
After having performed the pre-scanning process of S01 step, perform S02 step, calculate signal collected frequency
Spectral structure.Take amplitude after the 7 groups of signals collected in S01 step are carried out Fourier transformation, obtain it
Spectrum distribution, as shown in Figure 3.Assume that current system mid frequency is calibrated, then the radio frequency letter of sampling
After number being modulated demodulation, Qi Shui peak 3 will 0 hertz (Hz) of alignment, fat peak 4 is distributed near-200Hz.
After obtaining described signal spectrum scattergram by S02 step, perform S03 step, to 7 groups of signals
Near fat peak 4, choose certain bandwidth respectively carry out signal integration, as fat signal strength Sf, this reality
Execute and example is chosen the bandwidth of 100Hz carry out signal integration.
Obtain 7 groups of data respective fat signal strength SfAfter, perform S04 step, by each group of data generation
Enter the assessment formula R=1/S of systemic presuppositionfIn, it is thus achieved that 7 R values, R the biggest representative pressure fat effect is the best,
System chooses the pressure fat pulse parameter that group parameter corresponding to the R value of maximum is used as clinic automatically.
It should be noted that the adjustable parameter of the pressure fat pulse of pre-scanning process is that frequency is inclined in the present embodiment
Put, excite bandwidth, flip angle etc. for preset parameter, but the most also can by excite bandwidth or
Flip angle or other parameters are adjustable parameter, and remaining performs prescan, set-up mode and behaviour for preset parameter
Making process identical with foregoing, here is omitted.
Press fat pulse parameter system of selection corresponding to above-mentioned self adaptation, present invention also offers a kind of self adaptation
Pressure fat pulse parameter select device, Fig. 6 is the structural representation of this device, as shown in Figure 6, described from
Adapt to pressure fat pulse-selecting apparatus include:
Pre-scan module 5, for gathering target area signal under the pressure fat impulse action of different parameters；
Spectrum distribution computing module 6, for calculating the spectrum distribution of described signal；
Signal intensity calculates module 7, is used for calculating water signal intensity SwAnd/or fat signal strength Sf；
Evaluation module 8, for according to the assessment formula R=S presetw/SfOr R=Sw 2/SfOr R=1/Sf, calculate
Water signal intensity SwAnd/or fat signal strength SfNumerical relation, according to assessment result, largest r value institute
That corresponding group pulse parameter is optimal pressure fat parameter, will be automatically stored as the pressure fat of clinical scanning by system
Pulse parameter.
Calculate as it is shown in fig. 7, described signal intensity calculates the internal water signal intensity that is further divided into of module 7
Module 71 and fat signal Strength co-mputation module 72, be respectively used to calculate described water signal intensity SwAnd fat
Signal intensity Sf。
Although the present invention announces as above with preferred embodiment, but it is not for limiting the present invention,
Any those skilled in the art without departing from the spirit and scope of the present invention, may be by the disclosure above
Method and technology contents technical solution of the present invention is made possible variation and amendment, therefore, every not
Depart from the content of technical solution of the present invention, according to appointing that above example is made by the technical spirit of the present invention
What simple modification, equivalent variations and modification, belong to the protection domain of technical solution of the present invention.
Claims (10)
1. a self adaptation pressure fat pulse parameter system of selection, including:
Prescan, gathers target area signal under the pressure fat impulse action of different parameters；
Calculate the spectrum distribution of described signal；
Calculate water signal intensity SwWith fat signal strength Sf；
Assess the effect of each group of pressure fat pulse, calculate water signal intensity S by the assessment formula of systemic presuppositionwAnd/or fat signal strength SfNumerical relation R；
By the pressure fat pulse parameter that one group of parameter apolegamy is clinical scanning corresponding to maximum numerical relation R.
2. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 1, it is characterised in that: described assessment formula is:
R=Sw/Sf 。
3. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 1, it is characterised in that: described assessment formula is:
R=Sw 2/Sf
。
4. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 1, it is characterised in that: described assessment formula is:
R=1/Sf 。
5. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 1, it is characterised in that: obtain spectrum distribution by taking amplitude after described signal is carried out Fourier transformation.
6. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 1, it is characterised in that: the scanning sequence that described prescan uses is by pressing fat module and regioselectivity sequence to form.
7. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 6, it is characterised in that: the scanning sequence that described prescan uses is by pressing fat module and STEAM sequence to form.
8. a kind of self adaptation pressure fat pulse parameter system of selection as claimed in claim 6, it is characterised in that: the scanning sequence that described prescan uses is by pressing fat module and PRESS sequence to form.
9. self adaptation pressure fat pulse parameter selects a device, including:
Pre-scan module, for gathering target area signal under the pressure fat impulse action of different parameters；
Spectrum distribution computing module, for calculating the spectrum distribution of described signal；
Signal intensity calculates module, is used for calculating water and/or fat signal intensity；
Evaluation module, for calculating water signal intensity and/or numerical relation R of fat signal intensity according to the assessment formula preset, determines optimal pressure fat parameter according to result of calculation.
10. a kind of self adaptation pressure fat pulse parameter as claimed in claim 9 selects device, it is characterised in that: described signal intensity calculates module and includes that water signal intensity calculates module and fat signal Strength co-mputation module.
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