CN106035369A - Lepimectin and Profenofos contained compound insecticidal composition and use thereof - Google Patents
Lepimectin and Profenofos contained compound insecticidal composition and use thereof Download PDFInfo
- Publication number
- CN106035369A CN106035369A CN201610451340.5A CN201610451340A CN106035369A CN 106035369 A CN106035369 A CN 106035369A CN 201610451340 A CN201610451340 A CN 201610451340A CN 106035369 A CN106035369 A CN 106035369A
- Authority
- CN
- China
- Prior art keywords
- profenofos
- lepimectin
- pesticide compositions
- compound pesticide
- insecticidal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- QYMMJNLHFKGANY-UHFFFAOYSA-N profenofos Chemical compound CCCSP(=O)(OCC)OC1=CC=C(Br)C=C1Cl QYMMJNLHFKGANY-UHFFFAOYSA-N 0.000 title claims abstract description 72
- HICUREFSAIZXFQ-JOWPUVSESA-N i9z29i000j Chemical compound C1C[C@H](C)[C@@H](CC)O[C@@]21O[C@H](C\C=C(C)\[C@H](OC(=O)C(=N/OC)\C=1C=CC=CC=1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 HICUREFSAIZXFQ-JOWPUVSESA-N 0.000 title claims abstract description 58
- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 150000001875 compounds Chemical class 0.000 title claims abstract description 27
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 22
- 239000000575 pesticide Substances 0.000 claims abstract description 35
- 241000238631 Hexapoda Species 0.000 claims abstract description 9
- 241000255777 Lepidoptera Species 0.000 claims abstract description 9
- 239000006071 cream Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000002917 insecticide Substances 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 6
- 241000255893 Pyralidae Species 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 239000002671 adjuvant Substances 0.000 claims description 3
- 239000006185 dispersion Substances 0.000 claims description 3
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000000839 emulsion Substances 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- 239000004530 micro-emulsion Substances 0.000 claims description 3
- 230000000361 pesticidal effect Effects 0.000 claims description 3
- 239000000375 suspending agent Substances 0.000 claims description 3
- 239000004563 wettable powder Substances 0.000 claims description 3
- 229920000742 Cotton Polymers 0.000 claims 1
- 241000607479 Yersinia pestis Species 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 9
- 239000003795 chemical substances by application Substances 0.000 abstract description 6
- 230000002195 synergetic effect Effects 0.000 abstract description 3
- 239000004480 active ingredient Substances 0.000 abstract description 2
- 241001147381 Helicoverpa armigera Species 0.000 abstract 1
- 210000004894 snout Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 description 18
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 15
- 238000002156 mixing Methods 0.000 description 15
- 241000255967 Helicoverpa zea Species 0.000 description 13
- 239000003814 drug Substances 0.000 description 10
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 9
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 9
- 239000002994 raw material Substances 0.000 description 9
- 230000008485 antagonism Effects 0.000 description 8
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 7
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 6
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 6
- 241000426497 Chilo suppressalis Species 0.000 description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- -1 polyoxyethylene Polymers 0.000 description 5
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000012071 phase Substances 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 2
- 235000012211 aluminium silicate Nutrition 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 238000004166 bioassay Methods 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- UUIPAJHTKDSSOK-UHFFFAOYSA-N (2-nonylphenyl) dihydrogen phosphate Chemical compound CCCCCCCCCC1=CC=CC=C1OP(O)(O)=O UUIPAJHTKDSSOK-UHFFFAOYSA-N 0.000 description 1
- 239000005660 Abamectin Substances 0.000 description 1
- 239000004190 Avilamycin Substances 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 241001498622 Cixius wagneri Species 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108090000371 Esterases Proteins 0.000 description 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 description 1
- 241001597008 Nomeidae Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 239000004141 Sodium laurylsulphate Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- QHAGBBFNSJTDLV-UHFFFAOYSA-N [P].[Cl].[Br] Chemical compound [P].[Cl].[Br] QHAGBBFNSJTDLV-UHFFFAOYSA-N 0.000 description 1
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical group CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
- 229960004373 acetylcholine Drugs 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 229960005185 avilamycin Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000002532 grape seed extract Nutrition 0.000 description 1
- 150000002391 heterocyclic compounds Chemical class 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 230000007115 recruitment Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 210000000225 synapse Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000004562 water dispersible granule Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
- A01N57/14—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing aromatic radicals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a Lepimectin and Profenofos containing compound insecticidal composition and use thereof. The insecticidal composition employs Lepimectin and Profenofos as insecticidal active ingredients, wherein the weight ratio of the Lepimectin to the Profenofos is (0.1 to 80) to (0.5 to 80). The insecticidal composition can generate a relatively high synergistic effect, the pesticide resistance of insect pests is overcome and retarded, the insecticidal speed is high, and the effect duration is long, so that the pesticide use cost is reduced, and the control efficiency is apparently higher than that of a single agent. The insecticidal composition can be used for preventing and treating Lepidoptera pests on crops and particularly can be used to prevent and treat Helicoverpa armigera and snout moth's larva, and the control efficiency is apparently higher than that of the single agent.
Description
Technical field
The invention belongs to the field of agricultural pesticide containing heterocyclic compound, concrete body relates to a kind of composite insecticidal combination
Thing.
Background technology
Lepimectin, is by the derivant of Japan three mibemycin (milbemycin) A3/A4 that company finds altogether,
Used in Japan's registration in 2006.As novel pesticide for vegetable and water such as Caulis et Folium Brassicae capitatae, Fructus Lycopersici esculenti, Citrus, Fructus Fragariae Ananssae and Fructus Vitis viniferaes
Really, the main preventing and treating insect such as Lepidoptera and Semiptera.This medical instrument has insecticidal activity high, and dosage is few, to person poultry safety, does not pollutes
Environment, specificity is strong, does not injure natural enemy, is not easy to produce the features such as resistance, can use with avermectins rotation, with
Anti-avilamycin produces resistance.Therefore it is referred to as the most promising wide spectrum, the insecticide of no interactions resistance efficient, novel at present
One of.Its mechanism of action is the permeability that can increase polypide nerve synapse caudacoria to C1-, thus the transmission of block nerves signal,
Insecticide neural paralysis is finally made to cause insect death.
Profenofos (profenofos) has another name called bromine chlorine phosphorus, many worms phosphorus, and chemical name is: O-(4-bromo-2-chlorphenyl)-O-second
Base-S-propyl group-thiophosphate, structural formula is:
Profenofos is broad-spectrum organophosphorous pesticide, has quick-acting, has preferable permeability on plant leaf blade.Its effect
Mechanism is acetylcholine esterase in suppression insect bodies, have tag, stomach toxicity and stifling three kinds of model of action, its insecticidal spectrum is wide, toxicity relatively
Low, efficient equally to above and below ground insect, it is preventing and treating grain, fruit tree, vegetable and the preferable insecticide of other industrial crops insect pests,
Especially prominent to the prevention effect of subterranean pest-insect, it is particularly suitable for the production of pollution-free vegetable.
Insecticide variety containing single component often existing defects in pesticide Pest control: use continuously easily produce anti-
The property of medicine, insecticidal spectrum is narrow, it is impossible to providing comprehensively protection for crop, peasant's drug cost is high.
Summary of the invention
It is an object of the invention to provide a kind of containing Lepimectin with the compound pesticide compositions of Profenofos, this Insecticidal combinations
Thing is the multifunctional insecticide compositions of preventing and treating lepidoptera pest.
It is a further object of the present invention to provide this Pesticidal combination and prevent and treat the insecticidal materials of resistance lepidoptera pest in preparation
On application, particularly preparation preventing and treating bollworm or snout moths larva insecticidal materials on application.
It is an object of the invention to be achieved through the following technical solutions:
A kind of containing Lepimectin with the compound pesticide compositions of Profenofos, this compound pesticide compositions is with Lepimectin
Being principle active component with Profenofos, wherein, the weight ratio of Lepimectin and Profenofos is 0.1～80:0.5～80.
In this compound pesticide compositions, the weight ratio of Lepimectin (A) and Profenofos (B) is preferably 1～60:1～60,
More preferably 1～40:1～40, most preferably 1～30:1～30.
In some preferred technical schemes: Lepimectin and Profenofos can 1:30,1:29,1:28,1:27,1:
26、1:25、1:24、1:24、1:22、1:21、1:20、1:19、1:18、1:17、1:16、1:15、1:14、1:13、1:12、1:
11、1:10、1:9、1:8、1:7、1:6、1:5、1:4、1:3、1:2、1:1、2:1、3:1、4:1、5:1、6:1、7:1、8:1、9:1、
10:1、11:1、12:1、13:1、14:1、15:1、16:1、17:1、18:1、19:1、20:1、21:1、22:1、23:1、24:1、
25:1、26:1、27:1、28:1、29:1、30:1、2:3、3:2、2:5、5:2、3:4、4:3、5:2、2:5、5:3、3:5、5:4、4:5
These ratios select.
This compound pesticide compositions can comprise only active component Lepimectin and Profenofos, it is possible to when using or prepare
Adding other components in active component, the active ingredient in this Pesticidal combination can be present in compositions with enhancing effective amount
In.
In compound pesticide compositions of the present invention, Lepimectin and both Profenofos are in this compound pesticide compositions
Weight percentage is 3%～80%.It is preferably 5%～55%, most preferably 10%～40%.
Compound pesticide compositions of the present invention is with Lepimectin and Profenofos as active component or principle active component, and agriculture
Medicine auxiliary agent is configured on pesticide any one dosage form allowed, the preferred cream of described dosage form, suspending agent, wettable powder, water
Emulsion, microemulsion or water dispersion granule.
The insecticides adjuvant of the aforementioned present invention of can be applicable to is not particularly limited, and includes, but are not limited to detergent alkylate
Sulfoacid calcium, 600#, polyoxyethylene polyoxy propylene block compound are (such as agriculture breast 33#), NPE etc., aforementioned should
Excipient for the present invention is also not particularly limited, include, but are not limited to solvent naphtha, water, antifreezing agent (such as propylene glycol),
Deionized water etc..Above auxiliary agent, excipient and other adjuvant can be alone or and use.
Compound pesticide compositions of the present invention easily produces multiple Semiptera and the Lepidoptera of resistance to planthopper and snout moths larva etc.
Insect has good preventive effect；And suppress insect that the Drug resistance of unitary agent (Lepimectin or Profenofos are arbitrary) is produced
Raw.
Above-mentioned compound pesticide compositions prevents and treats the application on resistance lepidoptera pest insecticidal materials in preparation, especially in system
Application effect on standby preventing and treating bollworm or snout moths larva insecticidal materials is notable.
Compared with prior art beneficial effects of the present invention: (1) compared with single dose, said composition antagonism lepidoptera pest
As bollworm, snout moths larva etc. have obvious synergistic function, overcoming and delayed pest resistance to insecticide, expanding prevention is composed, parasite killing speed
Hurry up, hence it is evident that improve prevention effect；(2) preventing and treating recruitment, drug cost are reduced；(3) alternative high-toxic pesticide；(4) have concurrently quick-acting
With long-acting；(5) with Lepimectin compared with Profenofos single dose, produce and use cost reduces；(6) suppression lepidoptera pest pair
The resistance of pesticide strengthens, and its effect uses apparently higher than its single dose.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but limits the present invention never in any form.
Embodiment 1:
Weigh 80gLepimectin, 2g Profenofos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, two
Toluene puts into mixing in mixing kettle to 100g, the method that above raw material is prepared cream routinely, forms principle active component weight
Amount percentage composition is the Lepimectin Profenofos cream of 82%.
Embodiment 2:
Weigh 2gLepimectin, 80g Profenofos, lignin 10g, Negel 2g, add to 100g with Kaolin,
Above raw material is mixed in super micron mill, forms the Lepimectin that principle active component weight percentage is 82%
Profenofos wettable powder.
Embodiment 3:
Weigh 60gLepimectin, 2g Profenofos, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 6g, two
Toluene adds to 100g, and the method that above raw material is prepared cream routinely puts into mixing in mixing kettle, forms principle active component
Weight percentage is the Lepimectin Profenofos cream of 62%.
Embodiment 4:
Weigh 2gLepimectin, 60g Profenofos, nonyl phenol phosphate 5g, alkylphenol polyoxyethylene 4g, n-butyl alcohol
The dimethylbenzene of 3g, 10g and the ketopyrrolidine of 10g, the xanthan gum of 0.1g, remaining supplies 100g, n-butyl alcohol and water dissolution shape with water
Becoming aqueous phase, remaining component mix and blend forms oil phase, slowly aqueous phase is added in oil phase, and continue to cut under cutter effect
Cut 10～30 minutes, form the Lepimectin profenofos emulsion in water that principle active component weight percentage is 62%.
Embodiment 5:
Weigh 40gLepimectin, 2g Profenofos, calcium dodecyl benzene sulfonate 5g, alkylphenol polyoxyethylene 4g, 30g
Solvent xylene and the ketopyrrolidine of 15g, remaining complements to 100g with water, and the mixing of former medicine, solvent, emulsifying agent, cosolvent is stirred
Mix formation homogeneous phase transparent solution, be then slowly added into water and stir formation clear solution, being principle active component weight percent
Content is the Lepimectin Profenofos microemulsion of 42%.
Embodiment 6:
Weigh 2gLepimectin, 40g Profenofos, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 3g, two
Toluene is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, forms principle active component weight
Amount percentage composition is the Lepimectin Profenofos cream of 42%.
Embodiment 7:
Weigh 20gLepimectin, 2g Profenofos, sodium lignin sulfonate 3g, polyoxyethylene poly-oxygen propylene aether and sulphuric acid thereof
Salt 4g, xanthan gum 0.2g, ethylene glycol 10g, silica ethane 0.1g, aluminium-magnesium silicate 0.5g, supply 100g with water, at the work of sand mill
With the Lepimectin Profenofos suspending agent that lower formation principle active component weight percentage is 22%.
Embodiment 8:
Weigh 2gLepimectin, 20g Profenofos, alkylphenol polyoxyethylene 14g, phenethyl phenol polyethenoxy ether 15g,
Dimethylbenzene puts into mixing in mixing kettle to 100g, the method that above raw material is prepared cream routinely, forms principle active component
Weight percentage is the Lepimectin Profenofos cream of 22%.
Embodiment 9:
Weigh 10gLepimectin, 2g Profenofos, sodium lignin sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g,
Polyvinyl alcohol 5g, Borax 2g, Kaolin 28g, the method that above raw material is pressed water dispersion granule forms principle active component weight
Amount percentage composition is the Lepimectin Profenofos water dispersible granules of 12%.
Embodiment 10:
Weigh 10gLepimectin, 5g Profenofos, alkylphenol polyoxyethylene 14g, phenethyl phenol polyethenoxy ether 15g,
Dimethylbenzene puts into mixing in mixing kettle to 100g, the method that above raw material is prepared cream routinely, forms principle active component
Weight percentage is the Lepimectin Profenofos cream of 15%.
Embodiment 11:
Weigh 10gLepimectin, 10g Profenofos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g,
Dimethylbenzene puts into mixing in mixing kettle to 100g, the method that above raw material is prepared cream routinely, forms principle active component
Weight percentage is the Lepimectin Profenofos cream of 20%.
Drug effect checking test
1, indoor virulence determination of activity
Weigh Lepimectin and Profenofos 30g, calcium dodecyl benzene sulfonate 4g altogether, phenethyl phenol polyethenoxy ether 4g,
Vegetable oil is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is configured to main effectively one-tenth
The Lepimectin Profenofos cream dividing weight percentage to be 30%.Wherein Lepimectin and the concrete ratio of Profenofos
It is shown in Table 1 and 2.
Using feedstuff to add poison method and carry out indoor potentiation bioassay, selection resistant bollworm is target pest, often processes weight
Multiple 3 times, every concentration processes 60, with probability value method calculate each medicament antagonism bollworm toxicity regression equation and lethal in dense
Degree LC50, use LC50Value press Sun Yun abundant method calculating co-toxicity coefficient, the results are shown in Table 1:
Table 1 Lepimectin, Profenofos and the toxicity test of compounding sample antagonism bollworm thereof and co-toxicity coefficient
In table, data show, antagonism bollworm are had potentiation, in table after Lepimectin and Profenofos mixture
Listed proportioning co-toxicity coefficient is both greater than 120, and therefore Lepimectin and Profenofos mixture have significant synergies.
Weigh Lepimectin, Profenofos uses conventional formulation method to be configured to principle active component weight by different proportion
Percentage composition is the Lepimectin Profenofos cream of 30%.Concrete ratio is shown in Table 2.
Using feedstuff to add poison method and carry out indoor potentiation bioassay, selection rice-stem borer is target pest, often processes weight
Multiple 3 times, calculate toxicity regression equation and lethal concentration of 50 LC of each medicament antagonism striped rice borer by probability value method50, use LC50Value
Calculate co-toxicity coefficient by the abundant method of Sun Yun, the results are shown in Table 2:
Table 2 Lepimectin, Profenofos and compounding sample thereof are to the toxicity test of striped rice borer and co-toxicity coefficient
In table, data show, have potentiation, institute in table after Lepimectin and Profenofos mixture to rice-stem borer
The proportioning co-toxicity coefficient of row is all much larger than 120, and therefore Lepimectin and Profenofos mixture have significant synergies.
2, field control effectiveness test
Using embodiment institute sample product to carry out the field test of control in field bollworm, comparison medicament is 40% Profenofos EC
With 10%LepimectinEC (cream), it is diluted according to the extension rate in form 3, after medicine, looks into 3 days, 7 days, the knot of 14 days
Really, result is shown in Table 3:
Table 3 Lepimectin-Profenofos compounds the field test results of antagonism bollworm
Example has fabulous quick-acting to antagonism bollworm as can be seen from Table 3, and the lasting period is long, in field
Performance is good, is the outstanding medicament preventing and treating antagonism bollworm.
Measure through indoor synergism test and show: by Lepimectin with Profenofos built agent to bollworm and rice-stem borer
There is significant synergistic insecticidal action；Field control effectiveness test also indicates that all of built agent of the present invention is to bollworm insecticidal effect equally
It is all remarkably higher than the effect of corresponding single dose pesticide.
Claims (10)
1. containing Lepimectin and a compound pesticide compositions for Profenofos, it is characterized in that this compound pesticide compositions with
Lepimectin and Profenofos are active insecticidal components, and wherein, the weight ratio of Lepimectin and Profenofos is 0.1～80:0.5
～80.
The most according to claim 1 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that described
The weight ratio of Lepimectin and Profenofos is 1～60:1～60.
The most according to claim 2 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that described
The weight ratio of Lepimectin and Profenofos is 1～40:1～40.
The most according to claim 3 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that described
The weight ratio of Lepimectin and Profenofos is 1～30:1～30.
The most according to claim 1 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that
Lepimectin and both Profenofos weight percentage in this compound pesticide compositions are 3%～80%.
The most according to claim 5 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that
Lepimectin and both Profenofos weight percentage in this compound pesticide compositions are 5%～55%.
The most according to claim 1 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that this is combined
With Lepimectin, as active insecticidal components and insecticides adjuvant is configured on pesticide the dosage form of permission to Pesticidal combination with Profenofos.
The most according to claim 7 containing Lepimectin with the compound pesticide compositions of Profenofos, it is characterized in that described dose
Type is cream, suspending agent, aqueous emulsion, wettable powder, microemulsion or water dispersion granule.
9. the compound pesticide compositions containing Lepimectin and Profenofos described in claim 1 prevents and treats resistance Lepidoptera in preparation
Application on the insecticidal materials of insect.
Compound pesticide compositions containing Lepimectin and Profenofos the most according to claim 9 is at preparation preventing and treating cotton boll
Application on the insecticidal materials of worm or snout moths larva.
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| CN107389927A (en) * | 2017-08-29 | 2017-11-24 | 联合益康（北京）生物科技有限公司 | A kind of time-resolved fluorescence test strips for detecting Profenofos and its application |
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