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CN105943046A - Tumor body impedance monitoring device and method based on abdominal aortic stent - Google Patents

Tumor body impedance monitoring device and method based on abdominal aortic stent Download PDF

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Publication number
CN105943046A
CN105943046A CN201610394055.4A CN201610394055A CN105943046A CN 105943046 A CN105943046 A CN 105943046A CN 201610394055 A CN201610394055 A CN 201610394055A CN 105943046 A CN105943046 A CN 105943046A
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impedance
integrated circuit
monitoring device
radio
frequency
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Inventor
任勇
王景璟
李�灿
孟越
马骏
李亮
吴巍巍
史清宇
刘磊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0538Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031Implanted circuitry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6862Stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6876Blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The invention relates to a tumor body impedance monitoring device and method based on an abdominal aortic stent. The tumor body impedance monitoring device comprises a covered stent, an integrated circuit and an external processing device. The integrated circuit is arranged outside the covered stent and comprises an energy supply module, an impedance measuring sensor, a memorizer, a data processor and a first radio-frequency transmitting-receiving module. The energy supply module is used for supply power for the integrated circuit. The impedance measuring sensor transmits a detected impedance signal to the data processor through the memorizer, the data processor converts the impedance signal into a digital signal, loads an integrated circuit ID and timestamp information and transmits the digital signal to the external processing device through the first radio-frequency transmitting-receiving module and the covered stent to complete data measuring and signal transmitting functions. The tumor body impedance monitoring device is small in size and small in radiation amount, meanwhile can conduct real-time monitoring on a patient and can be widely applied to abdominal aortic aneurysm state monitoring.

Description

Tumor body Impedance monitoring device based on ventral aorta support and method thereof
Technical field
The present invention relates to a kind of tumor body Impedance monitoring device and method thereof, especially with regard to one at medical treatment detection technique neck The tumor body Impedance monitoring device based on ventral aorta support applied in territory and method thereof.
Background technology
Along with aged tendency of population and the increase of the risk factor such as hypertension, arteriosclerosis, China's formation of abdominal aortic aneurysms Rate is obvious ascendant trend, and over-65s old people's formation of abdominal aortic aneurysms rate is up to 8.8%.Research shows, the most often 100000 people there are 20 people suffer from abdominal aortic aneurysm to 40 people.The ventral aorta of abnormal expansion is referred to as abdominal aortic aneurysm, it Although not being true neoplasm, but the harm to human body is the biggest, and tumor body ruptures and may result in death.Abdominal aortic aneurysm Formation is a progressive process, this progressive during, hereditism, environmentology and biochemistry factors phase Affect mutually, jointly act on, such as, change the metabolism of abdominal aorta wall elastic force connection tissue thus inspired ventral aorta The formation of tumor.
Interventional therapy becomes the modus operandi that abdominal aortic aneurysm is main at present.Support is imported aorta by this operation And it discharged in conduit, thus prevent aneurysm rupture.Due to the danger of abdominal aortic aneurysm, to ventral aorta Tumor carries out detecting particularly significant.At present, the inspection method of abdominal aortic aneurysm mainly includes color doppler ultrasonography, CTA And MRI etc..These methods above-mentioned are required for carrying out auxiliary detection by bigger equipment, can only carry out in hospital. And detect by these modes, all human body can be had than more serious radiation.
Summary of the invention
For the problems referred to above, it is an object of the invention to provide a kind of volume little, radiate little, patient can be carried out simultaneously The tumor body Impedance monitoring device based on ventral aorta support of monitoring in real time and method thereof.
For achieving the above object, the present invention takes techniques below scheme: a kind of tumor body impedance based on ventral aorta support Monitoring device, it is characterised in that: this device includes overlay film frame, integrated circuit and external processing apparatus;Described integrated Circuit is arranged on outside described overlay film frame, described integrated circuit include energy supply module, impedance measuring sensor, Memorizer, data processor and the first radio-frequency (RF) receiving and transmission module;Described energy supply module is for supplying for described integrated circuit Electricity;The impedance signal detected is transmitted to described data processor by described impedance measuring sensor through described memorizer, Impedance signal is converted into digital signal by described data processor, and loads described integrated circuit ID, timestamp information, By described first radio-frequency (RF) receiving and transmission module, digital signal is transferred to described external processing apparatus through described overlay film frame, complete Become DATA REASONING, signal emission function.
Further, described overlay film frame is used for carrying out energy and signal transmission as antenna, and it is by inner membrance, rack body Constitute with adventitia, be positioned at described rack body and be internally provided with described inner membrance, be positioned at outside described rack body and be provided with Described adventitia.
Further, described rack body includes plural bracing structure and more than one longitudinal support structure, Each described bracing structure is bent to form ring support by a tinsel, and all described ring supports are the most successively Arrange and be fixedly connected into one by longitudinal support structure described between ring support described in adjacent two.
Further, described ring support uses sinusoidal configuration, and described longitudinal support structure is fixedly installed on all described Ring support side, described longitudinal support structure is made up of another tinsel.
Further, described ring support uses sawtooth waveforms structure, all described ring supports and all described longitudinal bracings Structure uses same one metal wire to work out.
Further, resonant frequency f of described rack body:
1 f = C 1 N + C 2 n + C 3 l ,
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure Length, C1、C2And C3It is positive coefficient.
Further, described integrated circuit uses string configuration, and strip integrated circuit is axial arranged along overlay film frame.
Further, described integrated circuit uses square structure or loop configuration, is wrapped in described collection when using square structure The biological compatibility shell becoming circuit external uses circular configuration;When using loop configuration, annular integrated circuit place is put down Face is parallel with the tangent plane of overlay film frame.
Further, described external processing apparatus includes launching antenna, reception antenna, the second radio-frequency (RF) receiving and transmission module, process Device, transport module and work station;By described integrated in described transmitting sky alignment body of described second radio-frequency (RF) receiving and transmission module Circuit transmission electromagnetic transmission energy, the resistance that the described integrated circuit simultaneously and in described reception antenna receiving body sends Antinoise signal;The impedance signal received is sent extremely by described second radio-frequency (RF) receiving and transmission module through described processor, transport module Described work station.
A kind of monitoring method based on above-mentioned monitoring device, it is characterised in that the method comprises the following steps: 1) arrange The one monitoring dress including impedance measuring sensor, data processor, the first radio-frequency (RF) receiving and transmission module and external processing apparatus Putting, wherein, external processing apparatus includes reception antenna, the second radio-frequency (RF) receiving and transmission module, processor, transport module and work Stand;2) impedance signal that impedance measuring sensor gathers between abdominal aortic aneurysm and overlay film frame passes through data processor Transmitting after process to the first radio-frequency (RF) receiving and transmission module, the first radio-frequency (RF) receiving and transmission module is logical after being modulated the impedance signal received Cross antenna and be sent to external processing apparatus;3) impedance signal received is entered by reception antenna through the second radio-frequency (RF) receiving and transmission module It is sent to work station after row demodulation and after the process of treated device, completes monitoring.
Due to the fact that and take above technical scheme, it has the advantage that 1, due to the fact that and take real-time self-service inspection The mode surveyed, patient can understand self health status whenever and wherever possible without going to hospital, convenient and swift.2, compared to Detecting tumor by conventional diagnostic modes such as radiographies, the present invention is from radiation, and due to abdomen actively in the past Arteries and veins tumor patient suffers from renal dysfunction the most simultaneously, carries out the contrast agent of input during radiography and is likely to cause patient's kidney merit Can deteriorate and even result in renal failure, therefore instant invention overcomes the time manpower caused when existing radiography mode detects internal hemorrhage due to trauma Material resources cost height the problem that patient health situation is constituted a serious threat.3, the present invention can implant at operative treatment Impedance detection integrated circuit is implanted, it is to avoid the misery of patient's second operation while support.The present invention can be extensively at abdomen The status monitoring of aortic aneurysm is applied.
Accompanying drawing explanation
Fig. 1 is the monitoring device principle schematic of the present invention;
Fig. 2 is structural representation during data processor employing NRF51822 chip in integrated circuit of the present invention;
Fig. 3 is the external equipment principle schematic of the present invention;
Fig. 4 is the antenna structure view of the sine wave shape of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is carried out detailed description.It should be appreciated, however, that being provided only more of accompanying drawing Understanding the present invention well, they should not be interpreted as limitation of the present invention.
Why electrical impedance technology can rebuild the electrical parameter distribution within biological tissue, comes from biological tissue and has electricity Magnetism characteristic.For human body, the main source of various electrical characteristics and electrical activity be biomacromolecule, particle, water and The electrology characteristic of the free electron of a small amount of transient state and motion thereof produce.Research shows, not only the electricity between normal structure Characteristic is big especially, and the electrical characteristics difference between organism normal structure and pathological tissues is the biggest.According to state foreign minister The measurement result of the fibromyoma of Mus is found after the fibromyoma of Mus occurs by pass personnel, the dielectric constant of malignant tumor The highest with conductivity.But it is as the growth of tumor, dielectric constant and electrical conductivity not change significantly.When bigger Tumor when occurring internal downright bad, the change of dielectric constant and electrical conductivity is the least after frequency is higher than 0.5GHz.
As it is shown in figure 1, based on above-mentioned principle, the present invention provides a kind of tumor body impedance monitoring based on ventral aorta support Device, it includes overlay film frame, integrated circuit and external processing apparatus.
Overlay film frame is used for carrying out energy and signal transmission as antenna, and it is made up of inner membrance, rack body and adventitia, It is positioned at rack body and is internally provided with inner membrance, be positioned at outside rack body and be provided with adventitia.
Integrated circuit is arranged on outside overlay film frame, can be installed on adventitia by integrated circuit, it is also possible to by integrated electricity Road is placed between overlay film frame and tumor body independent of support.This integrated circuit includes energy supply module, impedance measurement Sensor, memorizer, data processor and the first radio-frequency (RF) receiving and transmission module.Energy supply module is penetrated by first through antenna Frequently transceiver module receives and is radiated to internal electromagnetic wave by external processing apparatus, by the way of radio frequency energy is collected Power for miscellaneous part on integrated circuit.The impedance signal stored device transmission extremely number that impedance measuring sensor will detect According to processor, impedance signal is converted into digital signal by data processor, and loads the letters such as integrated circuit ID, timestamp Breath, by the first radio-frequency (RF) receiving and transmission module by digital signal through antenna transmission to external processing apparatus, complete DATA REASONING, Signal emission function.Wherein, energy supply module can also use minicell as an alternative, in order to is directly integrated Each parts on circuit are powered.
In a preferred embodiment, as in figure 2 it is shown, data processor can use and be produced by NORDIC company NRF51822 chip.This chip ADC switched pins J6 connects impedance measuring sensor, and VDD power pins J1 connects Energy supply module, XC1, XC2 pin J37-J38 connects clock circuit, VDD_PA, ANT1, ANT2 pin J30-J32 Connect the first radio-frequency (RF) receiving and transmission module.P0.01 pin J5 connects power sense circuit, and DEC1 pin J39 is through the 3rd electric capacity C3 ground connection;Ground connection after VSS pin J33, J34 parallel connection, connects energy supply mould after VSS pin J33, J34 parallel connection Block, the 4th electric capacity C4 in parallel between AVDD pin with VSS pin.DEC2 pin J29 is through the tenth electric capacity C10 Ground connection after being connected with EXP_GND pin J49;VSS pin J13 ground connection, SWCLK pin is through the 3rd resistance R3 ground connection.
Wherein, clock circuit includes the first electric capacity C1, the second electric capacity C2 and crystal oscillator X1, and crystal oscillator X1 controls end pin 1 Through the second electric capacity C2 ground connection, crystal oscillator X1 outfan pin 2 is through the first electric capacity C1 ground connection;Crystal oscillator X1 controls end pin The 1 XC1 pin J37 being additionally coupled to NRF51822 chip, crystal oscillator X1 outfan pin 2 is additionally coupled to NRF51822 The XC2 pin J38 of chip.
Power sense circuit includes the first resistance R1, the second resistance R2 and electric capacity C13, and the first resistance R1 mono-terminates height Level (i.e. energy supply module), the first resistance R1 other end is through the second resistance R2 ground connection;It is positioned at the second resistance R2 Two ends are parallel with between electric capacity C13, and the first resistance R1 other end and the second resistance R2 and are connected to by wire The P0.01 pin J5 of NRF51822 chip.
In above-described embodiment, as it is shown on figure 3, external processing apparatus includes launching antenna, reception antenna, the second radio frequency Transceiver module, processor, transport module and work station.By the collection in the second radio-frequency (RF) receiving and transmission module emitted sky alignment body Become circuit transmission electromagnetic transmission energy, simultaneously and the impedance signal that sends of the integrated circuit that is received in antenna receiving body; The treated device of impedance signal received, transport module are sent to work station by the second radio-frequency (RF) receiving and transmission module, in case follow-up Use.Wherein, work station can use the mobile terminal such as smart mobile phone, intelligent watch.
In a preferred embodiment, being provided with signal processing system in work station, signal processing system is according to setting Measure the resistance value obtained in time and judge aortic aneurysm thrombosis situation, if setting time internal impedance value beyond pre- If scope, then it is judged as that abdominal aortic aneurysm is still continuing hypertrophy, not by expecting normal thrombosis;If when setting Between within internal impedance value is in preset range, then be judged as the normal thrombosis of aortic aneurysm, the most gradually in atrophy.
In a preferred embodiment, as shown in Figure 4, rack body includes plural bracing structure 1 With more than one longitudinal support structure 2, each bracing structure 1 is bent to form ring support by a tinsel, All ring supports longitudinally set gradually and connect by a longitudinal support structure 2 is fixing between adjacent two ring supports Integral.
In above-described embodiment, ring support can use sinusoidal configuration or sawtooth waveforms structure.When ring support is just using During string wave structure, longitudinal support structure 2 is fixedly installed on all ring support sides, now this longitudinal support structure 2 It is made up of another tinsel;When ring support uses sawtooth waveforms structure, all ring supports and all longitudinal bracings knot Structure 2 uses same one metal wire to work out.
In above-described embodiment, all bracing structures 1 and longitudinal support structure 2 all can use Nitinol, doctor It is made with materials such as rustless steels.
In above-described embodiment, resonant frequency f of rack body:
1 f = C 1 N + C 2 n + C 3 l
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure 2 Length, C1、C2And C3It is positive coefficient.Wherein, N, n and l are the biggest, and resonant frequency is the least.During use, by In can not the size of adjusting pole main body, so by adjusting rising of waveform in quantity N of ring support, ring support Length l of voltage amount n and longitudinal support structure 2 carrys out adjusting pole main body as resonant frequency during antenna.
In a preferred embodiment, integrated circuit external is enclosed with biological compatibility shell, biological compatibility Shell is avoided that the rejection producing human body.Preferably, biological compatibility shell has certain pliability, can be curved Bent.The material of biological compatibility shell preferably employs polydimethylsiloxane (PDMS).During making, can be by integrated electricity Road is put in a mold, is filled with encapsulation with polydimethylsiloxane, prepares the integrated of band biological compatibility shell Circuit.
Integrated circuit is by flexible PCB and is formed on this flexible PCB each modular circuit chip system being made up of wafer Become, to adapt to volumetric constraint, and can be curved with the change of overlay film frame shape, but its length is propped up less than overlay film Frame length, its sectional area is less than 2mm × 1mm.
Integrated circuit uses string configuration, and strip integrated circuit is axial arranged along overlay film frame, can reduce integrated electricity The road impact on unobstructed blood vessel.
Integrated circuit uses square structure, is wrapped in its outside biological compatibility shell and uses circular configuration.
Integrated circuit uses loop configuration, and annular integrated circuit place plane is parallel with the tangent plane of overlay film frame.
Based on said apparatus, the present invention also provides for a kind of tumor body impedance monitoring method based on ventral aorta support.Below Being described in detail by specific embodiment uses the Impedance monitoring device based on endovascular stent for abdominal aorta of the present invention to abdomen master The detailed process that the impedance of aneurysm patient is monitored:
1, impedance measuring sensor gathers the impedance signal between abdominal aortic aneurysm and overlay film frame by data processor Transmitting after reason to the first radio-frequency (RF) receiving and transmission module, the first radio-frequency (RF) receiving and transmission module is passed through after being modulated the impedance signal received Antenna is sent to external processing apparatus.
2, by the impedance signal received, after the second radio-frequency (RF) receiving and transmission module is demodulated and treated device processes reception antenna After be sent to work station.
In a particular embodiment, the device based on impedance measurement detection abdominal aortic aneurysm thrombosis situation of the present invention is used To the abdomen process that actively overlay film frame duty detects:
The signal processing system being arranged in work station will receive abdominal aortic aneurysm and overlay film frame between resistance value with Preset value compares and judges aortic aneurysm thrombosis situation, if exceeding preset range setting time internal impedance value, Then it is judged as that abdominal aortic aneurysm is still continuing hypertrophy, not by expecting normal thrombosis;If setting time internal impedance Within value is in preset range, then it is judged as the normal thrombosis of aortic aneurysm, the most gradually in atrophy.Furthermore it is possible to The thrombosis situation of aortic aneurysm is judged further by the resistance value according to the aortic aneurysm obtained as reference value.
The various embodiments described above are merely to illustrate the present invention, and the structure of the most each parts, connected mode and processing technology etc. are all Can be varied from, every equivalents carried out on the basis of technical solution of the present invention and improvement, the most should not Get rid of outside protection scope of the present invention.

Claims (10)

1. a tumor body Impedance monitoring device based on ventral aorta support, it is characterised in that: this device includes that overlay film props up Frame, integrated circuit and external processing apparatus;Described integrated circuit is arranged on outside described overlay film frame, described integrated electricity Road includes energy supply module, impedance measuring sensor, memorizer, data processor and the first radio-frequency (RF) receiving and transmission module; Described energy supply module is used for as described integrated circuit;The impedance letter that described impedance measuring sensor will detect Number through the transmission of described memorizer to described data processor, impedance signal is converted into digital signal by described data processor, And load described integrated circuit ID, timestamp information, by described first radio-frequency (RF) receiving and transmission module by digital signal through described Overlay film frame is transferred to described external processing apparatus, completes DATA REASONING, signal emission function.
2. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 1, it is characterised in that: institute Stating overlay film frame as antenna for carrying out energy and signal transmission, it is made up of inner membrance, rack body and adventitia, position It is internally provided with described inner membrance in described rack body, is positioned at outside described rack body and is provided with described adventitia.
3. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 2, it is characterised in that: institute State rack body and include plural bracing structure and more than one longitudinal support structure, each described laterally Supporting construction is bent to form ring support by a tinsel, and all described ring supports longitudinally set gradually and adjacent It is fixedly connected into one by longitudinal support structure described between ring support described in two.
4. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 3, it is characterised in that: institute Stating ring support and use sinusoidal configuration, described longitudinal support structure is fixedly installed on all described ring support sides, Described longitudinal support structure is made up of another tinsel.
5. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 3, it is characterised in that: institute Stating ring support and use sawtooth waveforms structure, all described ring supports and all described longitudinal support structure use same Tinsel is worked out.
6. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 2 or claim 3, it is characterised in that: Resonant frequency f of described rack body:
1 f = C 1 N + C 2 n + C 3 l ,
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure Length, C1、C2And C3It is positive coefficient.
7. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 1, it is characterised in that: institute Stating integrated circuit and use string configuration, strip integrated circuit is axial arranged along overlay film frame.
8. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 1, it is characterised in that: institute State integrated circuit and use square structure or loop configuration, when using square structure, be wrapped in the life of described integrated circuit external Thing compatibility shell uses circular configuration;Annular integrated circuit place plane and overlay film frame when using loop configuration Tangent plane is parallel.
9. tumor body Impedance monitoring device based on ventral aorta support as claimed in claim 1, it is characterised in that: institute State external processing apparatus include launch antenna, reception antenna, the second radio-frequency (RF) receiving and transmission module, processor, transport module and Work station;Electromagnetic wave is launched by described second radio-frequency (RF) receiving and transmission module described integrated circuit in described transmitting sky alignment body Transmission energy, the impedance signal that the described integrated circuit simultaneously and in described reception antenna receiving body sends;Described The impedance signal received is sent to described work station by two radio-frequency (RF) receiving and transmission module through described processor, transport module.
10. one kind based on the monitoring method of monitoring device as described in any one of claim 1 to 9, it is characterised in that The method comprises the following steps:
1) arrange one to include impedance measuring sensor, data processor, the first radio-frequency (RF) receiving and transmission module and external treatment and set Standby monitoring device, wherein, external processing apparatus includes reception antenna, the second radio-frequency (RF) receiving and transmission module, processor, biography Defeated module and work station;
2) impedance measuring sensor gathers the impedance signal between abdominal aortic aneurysm and overlay film frame by data processor Transmitting after reason to the first radio-frequency (RF) receiving and transmission module, the first radio-frequency (RF) receiving and transmission module is passed through after being modulated the impedance signal received Antenna is sent to external processing apparatus;
3) by the impedance signal received, after the second radio-frequency (RF) receiving and transmission module is demodulated and treated device processes reception antenna After be sent to work station, complete monitoring.
CN201610394055.4A 2016-06-06 2016-06-06 Tumor body impedance monitoring device and method based on abdominal aortic stent Pending CN105943046A (en)

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CN101484070A (en) * 2006-07-21 2009-07-15 心脏起搏器公司 Multiple sensor deployment
CN104244866A (en) * 2012-04-27 2014-12-24 美敦力瓦斯科尔勒公司 Stent-graft prosthesis for placement in the abdominal aorta
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Application publication date: 20160921