CN105816663A - Traditional Chinese medicine composition with nutrition and anti-aging effects and facial cream and preparation methods thereof - Google Patents
Traditional Chinese medicine composition with nutrition and anti-aging effects and facial cream and preparation methods thereof Download PDFInfo
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- CN105816663A CN105816663A CN201610315391.5A CN201610315391A CN105816663A CN 105816663 A CN105816663 A CN 105816663A CN 201610315391 A CN201610315391 A CN 201610315391A CN 105816663 A CN105816663 A CN 105816663A
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- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
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Abstract
The invention relates to a traditional Chinese medicine composition with nutrition and anti-aging effects and a facial cream and preparation methods thereof, and belongs to the technical field of externally-applied traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from, by weight, 0.5-2 parts of herb of lysimachia foenum-graecum hance with roots, 0.5-2 parts of wrinkled gianthyssop herb, 0.5-2 parts of seeds of lily magnolia, 0.5-2 parts of rhizoma cyperi, 0.5-2 parts of Japanese snakegourd roots, 1-4 parts of castor seeds, 1-4 parts of peach kernels and 0.1-1 part of nux prinsepiae. A traditional Chinese medicine extract can be obtained by extracting the traditional Chinese medicine composition, an oil phase and a water phase are combined to serve as the raw material, and the facial cream is obtained. The facial cream has the efficacy of nutrition, moisturizing, whitening, wrinkle resisting and the like and has the effects of resisting bacteria, balancing skin micro-ecology, improving skin texture, maintaining and improving skin functions and the like; for the beauty-damage skin problem troubling females nowadays, the facial cream is definite in action mechanism and significant in effect and is consistent with a development trend of traditional Chinese medicine cosmetics.
Description
Technical field
The present invention relates to a kind of there is the Chinese medicine composition of nutrition Antiageing effect, facial cream and preparation method thereof, belong to Chinese medicine for outer use technical field.
Background technology
Now, due to increasing the weight of and the increasing of poisonous and harmful substance in air of the change of weather and the various pollutions such as environment, food, external chemical substance, in addition work, the increase of life stress, make the health of most of women move towards subhealth state, even senilism phenomenon is the most universal.Skin of face senilism is one of the most obvious feature, mainly show: the colour of skin is sallow or color and luster is uneven or pigmentation occurs, the unclean easy long small pox of skin pore, some skin exsiccation coarse wrinkles increase, some thinning of skin easily peel bits blood capillary obvious, or skin resistance to reduce the comparison become sensitive, or when communication in season or climate change, allergic conditions and a series of side reactions such as erythema, pimple, pruritus, decortication, swelling, scorching hot, pain, chance photostimulation aggravation easily occur.These symptoms all bring misery and worry to women, and somebody is even had influence at heart by the puzzlement of face, also have influence on normal work and life.
In addition to above-mentioned reason, cosmetics factor, chemical peeling, various skin care arts etc. are also one of reasons causing skin senilism.So, the most correctly select cosmetics, the most correctly select the beautifying technique of skin care and treatment, be also intended to one of vital task carrying out delay skin aging work.
Nowadays, skin care, delay skin aging cosmetics innumerable, of a great variety.From Cosmetic Market it can be seen that the high-quality cosmetics that favored by people or the most high in technological content, composition is natural.In recent years, along with the development of Chinese medicine beautifying cause grows, Chinese medicine cosmetic the most slowly entered the life of people.Owing to its composition is natural, the features such as external preparation for skin is safer, respond well, the most gradually liked by people.
Summary of the invention
It is an object of the invention to: the Chinese medicine composition of a kind of nutritious Antiageing effect, facial cream and preparation method thereof are provided.
According to the first aspect of the invention, a kind of Chinese medicine composition with nutrition Antiageing effect, includes following component by weight: Herba Lysimachiae foenum-graeci 0.5～2 parts, Herba Pogostemonis 0.5～2 parts, Flos Magnoliae core 0.5～2 parts, Rhizoma Cyperi 0.5～2 parts, Radix Trichosanthis Cucumeroidis 0.5～2 parts, Semen Ricini 1～4 parts, Semen Persicae 1～4 parts, prinsepaie,semen 0.1～1 part.
In one embodiment, proportioning is: Herba Lysimachiae foenum-graeci 1 part, Herba Pogostemonis 1 part, Flos Magnoliae core 1 part, Rhizoma Cyperi 1 part, Radix Trichosanthis Cucumeroidis 1 part, Semen Ricini 2 parts, 2.5 parts of Semen Persicae, prinsepaie,semen 0.5 part.
According to the second aspect of the invention, by the extracted Chinese medicine extract prepared of above-mentioned Chinese medicine composition.
According to the third aspect of the present invention, the preparation method of described Chinese medicine extract, comprises the steps: after Herba Lysimachiae foenum-graeci, Herba Pogostemonis, Flos Magnoliae core, Rhizoma Cyperi, the mixing of Radix Trichosanthis Cucumeroidis each Chinese medicinal components, with ethanol extraction, being concentrated by extracting solution, the Chinese medicine extraction liquid obtained is water-phase extract again；Being extracted by the mixture of Semen Ricini, Semen Persicae and prinsepaie,semen steam distillation, the vegetable oil obtained is oil-phased extract；Described Chinese medicine extract includes water-phase extract and oil-phased extract.
According to the fourth aspect of the present invention, the facial cream of above-mentioned Chinese medicine extract is included.
Described facial cream, it is to be prepared from by oil phase and aqueous phase, described oil phase includes monoglyceride 2% by weight percentage, C10～16 alkyl androstanediol 2%, emulsifying agent 1.5%, iso-octyl palmitate 3%, vaseline 1%, lanoline 1%, glycerol caprylate or certain herbaceous plants with big flowers acid glyceride 2%, polydimethylsiloxane 1.5%, cetearyl alcohol 3%, Cera Flava 1%, oil-phased extract 6%, methyl hydroxybenzoate 0.2%；Include azone 0.1% by weight percentage, glycerol 5%, carbomer 0.2%, water-phase extract 20%, triethanolamine 0.2%, antibacterial 0.1% in described aqueous phase, remaining is for deionized water；Described percentage by weight is the weight ratio that each component is shared in facial cream.
Described antibacterial refers to antibacterial MTI.
Described emulsifying agent refers to emulsifying agent A165.
The preparation method of described facial cream, comprises the following steps that the azone in aqueous phase, glycerol, carbomer, the mixing of deionization aqueous phase, obtains aqueous mixture；Again by after each for oil phase component mix homogeneously, add to aqueous phase, carry out homogenizing process；Sequentially add triethanolamine, water-phase extract, antibacterial, stir.
According to the fourth aspect of the present invention, the application in preparing skin protection cosmetics of above-mentioned Chinese medicine composition or Chinese medicine extract.
Described skin protection cosmetics refers to for improving mammal skin SOD activity, reducing MDA content or reduce the cosmetics of lipofuscin content.
Beneficial effect
The present invention is applied to beauty treatment clinic and life cosmetology, has the advantage that
1, natural Chinese medicines beauty treatment external preparation, effect is notable, to skin safe avirulence, nonirritant, without anaphylaxis;
2, the modern advanced technologies of application, permeability is good, can promote the skin absorption to its active substance, can effectively safeguard and promote physiological function and the metabolism of skin, and then improve skin texture, improve skin ageing symptoms;
3, this Chinese medicine facial cream can effectively activate skin SOD activity, improves and strengthen cutaneous circulation, suppresses tyrosinase activity, reduces the secretory function of melanocyte, promotes the metabolism of pigment;
4, there is good moist, tender white, moist and wrinkle resistant crease-resistant effect, also there is good heat-clearing and toxic substances removing, anti-inflammation and antianaphylactic effect simultaneously.The Aging skin such as the chronic poisoning skin causing mottle skin, the dark and gloomy sallow skin of corse sweat pore, coarse water deficient skin and solar dermatitis, red blood streak skin, a variety of causes and skin opposing function reduce, wrinkle is the most existing all have certain therapeutic effect and good beauty functions;
5, this Chinese medicine facial cream formula compatibility is rigorous.Dissect its composition to know, the party contains the nutritional labelings such as the vitamin needed for abundant human body skin, fatty acid, aminoacid, trace element, particularly containing multiple volatile oil in the party's composition, it is all the product of fragrance, not only loosing the interspaces of skin and muscles, saturating hair key, blood circulation promoting and blood stasis dispelling, improve local blood circulation and skin-nourishing situation, more can reduce cutaneous pigmentation, therefore be applied to beauty treatment clinic, effect is notable.
Detailed description of the invention
Chinese medicine composition employed in the present invention includes following component by weight: Herba Lysimachiae foenum-graeci 0.5～2 parts, Herba Pogostemonis 0.5～2 parts, Flos Magnoliae core 0.5～2 parts, Rhizoma Cyperi 0.5～2 parts, Radix Trichosanthis Cucumeroidis 0.5～2 parts, Semen Ricini 1～4 parts, Semen Persicae 1～4 parts, prinsepaie,semen 0.1～1 part of part.In a preferred embodiment, proportioning is Herba Lysimachiae foenum-graeci 1 part, Herba Pogostemonis 1 part, Flos Magnoliae core 1 part, Rhizoma Cyperi 1 part, Radix Trichosanthis Cucumeroidis 1 part, Semen Ricini 2 parts, 2.5 parts of Semen Persicae, prinsepaie,semen 0.5 part.
Herba Lysimachiae foenum-graeci, Herba Pogostemonis: reach on Herba Lysimachiae foenum-graeci gas perfume (or spice), warm in nature pungent scattered, enter lung meridian, lung qi dispersing gas, loosing the interspaces of skin and muscles, saturating hair key, dispersing wind and cold；Herba Pogostemonis is longer than removing dampness and pleases spleen, the fast gas of alleviating distention in middle-JIAO, also has the effect of antifungal, antiviral.Two medicines are all the product of fragrance, therefore mutual reinforcement between is use, then ward off dirty evil, dehumidifies turbid, the effect multiplication that Radix Saposhnikoviae is dispeled the wind.
Flos Magnoliae core: for the product of fragrance, can dispel the wind and have one's ideas straightened out, blood circulation promoting and blood stasis dispelling, improves the nutriture of local blood circulation and skin.This product is equal to Semen Persicae, Semen Armeniacae Amarum controls face with kind, also can be equal to use with Herba Asari, Rhizoma Polygonati Odorati, strengthen nourshing Yin and drynsessmoistening prescription effect of speckle of going out.Modern study finds that this product, mainly containing volatile oil, flavonoid, alkaloid and lignanoids material, has protection skin mucosa, promotes that secretions absorbs, the effect reduced inflammation；Meanwhile, also there is removing interior free yl, antioxidation, suppression tyrosinase activity suppression melanin release and then the effect of minimizing cutaneous pigmentation；And there is the effect such as heat-clearing and toxic substances removing, antiviral, skin various pathogens there is is obvious inhibitory action.
Rhizoma Cyperi: fragrant odour, happy color of preserving youthful looks, catharsis stagnation of liver-QI and face of controlling is dark etc..Its cured the disease card is mostly damage capacitive disease, is especially used for women because of symptoms such as the brown patch caused by stagnation of QI due to depression of the liver, the micro-Huang of skin and senilism.In vitro tests shows, Rhizoma Cyperi volatile oil significantly inhibits effect to staphylococcus aureus, and this volatile oil has slight estrogen-like effects.Its extract also has obvious inhibiting effect to some fungus.
Radix Trichosanthis Cucumeroidis: promoting blood circulation, repercussive speckle, control dark complexion acne vulgaris.Modern medicine study finds, has more than the 40 kind of plant factor useful to human skin, be one of ideal cosmetic composition in soil melon root.It, containing abundant vitamin C, fatty acid, aminoacid, carotene, choline etc., anti-wrinkle aging resistance, elimination speckle, eliminates cicatrix, promotes skin oxygen delivery capacity；Prevent moisture loss, make coarse skin become tender, compact, fine and smooth；Promote cutaneous circulation, improve metabolism, the sebum secretion that suppression is superfluous, remove the old refuse of skin, restrain pore.
Semen Ricini: Semen Ricini detumescence and drawing out poison, has and makes pathogenic QI in the body go out, the merit of looks improving and the skin nourishing hair care." Japan hanako materia medica ": " desolation mange also can grind deposited." zest of Oleum Ricini own is little, and pain relieving of having one's ideas straightened out, its property is walked to alter, thus cream film side multiplex it, can be as skin lubricant for dermatitis and other beauty treatment aspects, such as smoothing wrinkle, glabrous skin, improve skin allergy, dense hair and strengthen hair quality；It is also used for scalding and skin ulcer；Additionally can be used for blepharitis etc..
Semen Persicae: blood circulation promoting competent silt, skin moistening wrinkle removing, convergence pore, available pachylosis is dry and cracked, wrinkle, chloasma, skin itching, rosacea etc..Modern medicine study, this product contains amygdaloside, emulsin, volatile oil, fatty oil, mainly contains olein and a small amount of glyceryl linoleate in oil.Its extract can be obviously improved cutaneous circulation, and has the effects such as antiinflammatory, antibacterial and antiallergic.
Prinsepaie,semen: nourishing the liver to improve visual acuity, wind-dispelling heat-dissipating.Modern study shows, this product moisture content, protein, fat, fiber and oils and fats etc..Skin is had the effects such as moist nutrition, heat-clearing and toxic substances removing.
The extract of above-mentioned each component can be by the concentrate obtained after carrying out filtering, reduce pressure and concentrating after raw material impregnated in solvent and extracting.Above-mentioned solvent can be the mixture of the one or more in water, the anhydrous or aqueous alcohol of C1～C4, acetic acid, glycerol, propylene glycol and propylene glycol, but is not limited to this.Extraction can be stood by room temperature and carry out, but can promote to extract as desired by heating, stir, being heated to reflux.The extracting solution of gained can directly use, or implement suitably to filter, concentrate, decolouring etc. uses after processing.It is further possible to after temporarily removing solvent, use after carrying out re-dissolved in the solvent different from the solvent used by extraction.Use after the extract of gained can also be further purified by activated carbon, column chromatography etc..
In one embodiment, whole component is used ethanol extraction, then obtain extract after concentrating.
In another embodiment, after Herba Lysimachiae foenum-graeci, Herba Pogostemonis, Flos Magnoliae core, Rhizoma Cyperi, the mixing of Radix Trichosanthis Cucumeroidis each Chinese medicinal components, with ethanol extraction, then extracting solution is concentrated, obtain water-phase extract；The mixture of Semen Ricini, Semen Persicae and prinsepaie,semen steam distillation is extracted, obtains oil-phased extract.
Prepared by embodiment 1 Chinese medicine extract
Weighting raw materials by weight ratio: Herba Lysimachiae foenum-graeci 1 part, Herba Pogostemonis 1 part, Flos Magnoliae core 1 part, Rhizoma Cyperi 1 part, Radix Trichosanthis Cucumeroidis 1 part, Semen Ricini 2 parts, 2.5 parts of Semen Persicae, prinsepaie,semen 0.5 part.
By front five tastes crude drug mix homogeneously, use ultraviolet radiation sterilizing 50 minutes.
Being 75% ethanol extraction twice with percent by volume: extract for the first time crude drug with ethanol mass volume ratio g/ml as 1:15,60 DEG C of heated and stirred 1 hour, the filter-cloth filtering of 200 mesh obtains filtrate for the first time；It is 1:15 that second time extracts crude drug with ethanol mass volume ratio g/ml, 65 DEG C of heated and stirred 50min, and the filter-cloth filtering of 200 mesh obtains second time filtrate；To filtrate and second time filtrate mix for the first time, rotary evaporation is concentrated into 0.3g/ml, and the concentrated solution obtained is water-phase extract.Weigh Semen Ricini, Semen Persicae, prinsepaie,semen in proportion, smash to pieces after mixing, soak with 1:10 times of deionized water, use steam distillation to make water seethe with excitement 6-10 hour, obtain oil-phased extract.
Above-mentioned Chinese medicine extract includes water-phase extract and oil-phased extract two.
Embodiment 2
Weighting raw materials by weight ratio: Herba Lysimachiae foenum-graeci 1 part, Herba Pogostemonis 1 part, Flos Magnoliae core 1 part, Rhizoma Cyperi 1 part, Radix Trichosanthis Cucumeroidis 1 part, Semen Ricini 2 parts, 2.5 parts of Semen Persicae, prinsepaie,semen 0.5 part.
By front five tastes crude drug mix homogeneously, use ultraviolet radiation sterilizing 50 minutes.
Being 75% ethanol extraction twice with percent by volume: extract for the first time crude drug with ethanol mass volume ratio g/ml as 1:15,60 DEG C of heated and stirred 1 hour, the filter-cloth filtering of 200 mesh obtains filtrate for the first time；It is 1:15 that second time extracts crude drug with ethanol mass volume ratio g/ml, 65 DEG C of heated and stirred 50min, and the filter-cloth filtering of 200 mesh obtains second time filtrate；Filtrate and second time filtrate will mix for the first time, then process with 200 microns of micro-filtrate membrane filtrations, rotary evaporation is concentrated into 0.3g/ml, and the concentrated solution obtained is water-phase extract.The mixture of Semen Ricini, Semen Persicae and prinsepaie,semen steam distillation is extracted, obtains oil-phased extract.
Embodiment 3 facial cream makes
The composition of facial cream is to be mixed mutually with oil phase by aqueous phase, and composition is: include monoglyceride 2% by weight percentage, C12 alkyl androstanediol 2%, emulsifying agent A1651.5%, iso-octyl palmitate 3%, vaseline 1%, lanoline 1%, glycerol caprylate or certain herbaceous plants with big flowers acid glyceride 2%, polydimethylsiloxane 1.5%, cetearyl alcohol 3%, Cera Flava 1%, oil-phased extract 6%, methyl hydroxybenzoate 0.2% in oil phase；Aqueous phase includes azone 0.1% by weight percentage, glycerol 5%, carbomer 0.2%, embodiment 1 prepare water-phase extract 20%, triethanolamine 0.2%, antibacterial MTI0.1%, remaining is for deionized water；Described percentage by weight is the weight ratio that each component is shared in facial cream.
By the azone of above-mentioned aqueous phase, glycerol, carbomer, the mixing of deionization aqueous phase, when heated and stirred to temperature is 80～85 DEG C, it is incubated 10 minutes, obtains aqueous phase composition；Meanwhile, by above-mentioned oil phase is heated up to 80～85 DEG C after the mixing of each component, oil phase is joined in aqueous phase slowly, is ceaselessly stirred about 5 minutes, starts homogenizer, with 2000～3000s/min homogenizing 10～15min, be incubated 5 minutes.Then start stirring cooling, add triethanolamine；To be mixed being down to when 50 DEG C adds water-phase extract；Being stirred for uniform kettle temperature to be emulsified to be down to when 40～45 DEG C add antibacterial MTI, measure about pH=6.0 ± 2, end temperature is down to when 36 DEG C obtain facial cream.
Reference examples 1 beautifying face cream substrate
Difference with embodiment 3 is: do not add Chinese medicine extract (water-phase extract and oil-phased extract), and other aqueous phase is the most identical with the addition weight of oil phase.
The making of reference examples 2 facial cream
Difference with embodiment 1 and embodiment 3 is: do not add Semen Persicae in Chinese medicinal components, and the mixture steam distillation extraction taking Semen Ricini and prinsepaie,semen obtains oil-phased extract.
The test of pesticide effectiveness
1. animal model
Use Progesterone injection to attack combined uv and irradiate method reflex manufacture-yellow brown patch and the photoaging experimental animal model of female rats.
2. animal packet and administration
Take duplication successfully " chloasma and photoaging " female rat model 60, dosage group and model control group (reference examples 1 substrate) and positive controls (Azelaic Acid) totally six groups, often group 10 in dosage group, embodiment 3 facial cream low dose group, reference examples 2 facial cream it is randomly divided in embodiment 3 facial cream high dose group, embodiment 3 facial cream by body weight；Additionally take SPF level SD female green grass or young crops rat in age 10, be set to blank group.
Before experiment, lost hair or feathers in spinal column both sides, above 70 rat model backs by 24h depilatory cream.With clear water, depilatory cream residue is thoroughly cleaned up afterwards, with expose area as 3cm × skin of 3cm scope.
After observation skin is non-stimulated, high, medium and low dosage component is not with the ratio partial smearing beautifying face cream of the ratio of 0.08g/100g, the ratio of 0.04g/100g and 0.02g/100g；Model control group is in ratio partial smearing reference examples 1 substrate of high dose group；Positive controls is in the ratio partial smearing Azelaic Acid of high dose group.Once a day.Respectively 30 days (3 course for the treatment of) of the equal successive administration of group.Blank group to green grass or young crops rat in age, only carries out the depilation of same procedure but does not give any process factor.
3. skin biochemical indicator testing result
Rat skin tissue homogenate is carried out biochemical indicator detection, obtains experimental result with statistical method as follows:
(2) beautifying face cream is on chloasma and hydroxyproline, the impact of lipofuscin content in photoaging rat model skin
(see Table 2)
As can be seen from the above table, the facial cream that the present invention provides can significantly improve the activity of superoxide dismutase SOD in skin and the content of hydroxyproline, and, bring up to the level close to green grass or young crops rat in age, compare with model group, be respectively provided with the significance difference opposite sex (P ＜ 0.01).Improve the activity of SOD enzyme, it is simply that improve body and remove free radical and antioxidative ability；Meanwhile, the raising of hydroxyproline content in skin, show the raising of collagen protein synthesis ability in skin and the increase etc. of collagen fiber, this explanation, this Chinese medicine facial cream of external can promote the synthesis of skin collagen, thus reach the effect of delay skin aging.It addition, this Chinese medicine facial cream of external can substantially reduce MDA and the content of lipofuscin in skin, and, it is reduced to the level close to green grass or young crops rat in age, compares with model group, it may have the significance difference opposite sex (P ＜ 0.01).Lipofuscin content declines, and shows that body lipid levels of peroxide reduces, otherwise, illustrate that using this Chinese medicine facial cream to have significantly removes free radical and improve the effects such as oxidation resistance, thus promote body health, delayed skin aging.And reduce the content of MDA, namely reduce the MDA damage to cell tissue, so that skin function is recovered, really play and subtract the effect that wrinkle is anti-ageing.So, the mechanism of action is pointed out: external " beautifying face cream " has obvious face nourishing antidebilitation and effect of desalination mottle, and the Chinese medicine facial cream effect of middle dosage is the most obvious, and effect is notable.
Chinese medicine facial cream percutaneous dosing safety evaluatio
This experiment, with SPF level healthy SD rat as object of study, by percutaneous dosing, has carried out animal toxicity experiment, irritation test and sensitivity test.Result shows: no matter beauty treatment external facial cream acts on rat intact skin, or damaged skin, equal avirulence, nonirritant, without anaphylaxis.Show: beauty treatment external application Chinese medicine facial cream is safe and reliable in terms of preventing and improving skin aging.
The stability test of facial cream
Respectively according to the method for embodiment 3 prepared by the Chinese medicine extract prepared in embodiment 1 and embodiment 2 facial cream (being called the 1st group and the 2nd group), and carry out following stability test, result is as shown in table 3.
1.pH value；
2. heat resistant test, puts into calorstat (40 ± 1) DEG C the sample of Packing Intact and keeps 24h, recovers to observe with or without oil-water separation phenomenon to room temperature;
3. low temperature resistant test, the sample of Packing Intact put in refrigerator-5～-10 DEG C place 24h, recover to room temperature to observe with or without layering, coarse, metachromatism;
4. centrifugal test, places the sample of Packing Intact in centrifuge with 2000 revs/min, centrifugal 30 minutes, observes with or without oil-water separation phenomenon;
Table 3
| 1st group | 2nd group | |
| PH value | 6.5 | 6.4 |
| Heat resistant test | Phenomenon without oil-water separation | Phenomenon without oil-water separation |
| Low temperature resistant test | Trickle emulsifying shape granule is had to occur | Phenomenon without oil-water separation |
| Centrifugal test | Phenomenon without oil-water separation | Phenomenon without oil-water separation |
As can be seen here, the facial cream that prepared by the present invention has good stability.
The Chinese medicine composition of the present invention and the Economic Evaluation of facial cream:
In order to excavate Chinese medicine beautifying marrow, passing on Chinese medicine beautifying rarity, we have proposed the Chinese medicine composition of characteristic in the present invention, they are shown an interesting new approach, compatibility is rigorous.We are on traditional infrastructure, application modern production process, completed the facial cream in the present invention, finding through scientific experiment and clinical practice, this facial cream has nutrition, moisturizing, tender effect such as white, crease-resistant, and has antibacterial and balance skin Tiny ecosystem, improves skin texture, safeguards and promote the effects such as skin function, the damage U.S. property skin problem run into for current women, its mechanism of action is clear and definite, and effect is notable, matches with Chinese medicine cosmetic development trend.So, developing this prescription will have certain historic significance and realistic meaning.
China's traditional medicine is from Overall View, it is indicated that body aging be at all internal organs deficiency of five ZANG-organs damage, imbalance of YIN and YANG, i.e. " YIN and YANG in a relative equilibrium, life activities being normally maintained；Dissociation of YIN from YANG, exhaustion of vital essence ".So, strengthening the body resistance, regulating yin and yang are the key of slow down aging.The facial cream that the present invention provides just is based on " the body resistance strengthening and constitution consolidating, righting get rid of evils, QI and blood regulating, Yin Yang balancing " this theoretical basis and develops through advanced technologies.With the Herba Lysimachiae foenum-graeci of pleasant aroma, Herba Pogostemonis as principal agent in its composition, righting is got rid of evils；With soil melon root promoting blood circulation to remove blood stasis as accessory drugs, with Flos Magnoliae core, Rhizoma Cyperi as adjuvant drug, walnut core, prinsepaie,semen etc., carry out QI and blood regulating, Yin Yang balancing；Share by all medicines, reach effect of looks improving and the skin nourishing.
The facial cream green natural of present invention offer, safe without toxic side effect, beauty functions is notable, is suitable for the trend of modern cosmetics " back to nature ", also conforms to modern female and thirsts for skin health fitness, the year light and slow demand declined.So, develop this prescription and there is certain advance, marketability, have broad prospects and certain realistic meaning.
Raw material is wide, and cost is relatively low.China's Chinese herbal medicine resource enriches; Chinese herbal medicine original producton location is scientifically protected and introduces high-tech and carry out the focus that deep processing should be beauty treatment tcm product research and development; this development and utilization to promoting China's Chinese crude drug; drive the economic development of some areas, will have positive effect and far reaching significance.
Economic benefits, has certain economic worth.Facts have proved that the facial cream that the present invention provides is adapted to normal skin and the health maintenance of subhealth state skin and deep layer in various environment and maintains；Be adapted to the improvement of various aging skin, function is promoted and maintenance；The maintenance of the common U.S. sex chromosome mosaicism skin of damage occurred when being adapted to haze, sand and dust air and various environmental pollution and the various pressure of life and work, improve and reinvent.So, it is suitable for crowd extensive, accords with the demands of the market.If being invested in beauty treatment market, it is believed that objective economic benefit can be brought to cosmetic industry, there is certain economic worth.
Claims (9)
1. a Chinese medicine composition with nutrition Antiageing effect, it is characterized in that, include following component by weight: Herba Lysimachiae foenum-graeci 0.5～2 parts, Herba Pogostemonis 0.5～2 parts, Flos Magnoliae core 0.5～2 parts, Rhizoma Cyperi 0.5～2 parts, Radix Trichosanthis Cucumeroidis 0.5～2 parts, Semen Ricini 1～4 parts, Semen Persicae 1～4 parts, prinsepaie,semen 0.1～1 part.
The Chinese medicine composition with nutrition Antiageing effect the most according to claim 1, it is characterised in that component proportion is: Herba Lysimachiae foenum-graeci 1 part, Herba Pogostemonis 1 part, Flos Magnoliae core 1 part, Rhizoma Cyperi 1 part, Radix Trichosanthis Cucumeroidis 1 part, Semen Ricini 2 parts, 2.5 parts of Semen Persicae, prinsepaie,semen 0.5 part.
3. it is the extracted Chinese medicine extract prepared by the Chinese medicine composition with nutrition Antiageing effect described in claim 1.
4. the preparation method of the Chinese medicine extract described in claim 3, comprise the steps: after Herba Lysimachiae foenum-graeci, Herba Pogostemonis, Flos Magnoliae core, Rhizoma Cyperi, the mixing of Radix Trichosanthis Cucumeroidis each Chinese medicinal components, with ethanol extraction, then being concentrated by extracting solution, the Chinese medicine extraction liquid obtained is water-phase extract；Being extracted by the mixture of Semen Ricini, Semen Persicae and prinsepaie,semen steam distillation, the vegetable oil obtained is oil-phased extract；Described Chinese medicine extract includes water-phase extract and oil-phased extract.
5. include the facial cream of Chinese medicine extract described in claim 3.
Facial cream the most according to claim 5, it is characterized in that, it is to be prepared from by oil phase and aqueous phase, described oil phase includes monoglyceride 2% by weight percentage, C10～16 alkyl androstanediol 2%, emulsifying agent 1.5%, iso-octyl palmitate 3%, vaseline 1%, lanoline 1%, glycerol caprylate or certain herbaceous plants with big flowers acid glyceride 2%, polydimethylsiloxane 1.5%, cetearyl alcohol 3%, Cera Flava 1%, oil-phased extract 6%, methyl hydroxybenzoate 0.2%；Include azone 0.1% by weight percentage, glycerol 5%, carbomer 0.2%, water-phase extract 20%, triethanolamine 0.2%, antibacterial 0.1% in described aqueous phase, remaining is for deionized water；Described percentage by weight is the weight ratio that each component is shared in facial cream.
7. the preparation method of the facial cream described in claim 6, comprises the following steps that the azone in aqueous phase, glycerol, carbomer, the mixing of deionization aqueous phase, obtains aqueous mixture；Again by after each for oil phase component mix homogeneously, add to aqueous phase, carry out homogenizing process；Sequentially add triethanolamine, Chinese medicine extract, antibacterial, stir.
8. the Chinese medicine composition described in claim 1 or the Chinese medicine extract described in claim 3 application in preparing skin protection cosmetics.
Application the most according to claim 8, it is characterised in that described skin protection cosmetics refers to for improving mammal skin SOD activity, reducing MDA content or reduce the cosmetics of lipofuscin content.
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Application publication date: 20160803 |