CN105708588A - Degradable prostate stent - Google Patents
Degradable prostate stent Download PDFInfo
- Publication number
- CN105708588A CN105708588A CN201610034140.XA CN201610034140A CN105708588A CN 105708588 A CN105708588 A CN 105708588A CN 201610034140 A CN201610034140 A CN 201610034140A CN 105708588 A CN105708588 A CN 105708588A
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- China
- Prior art keywords
- degradable
- prostate
- stent
- rack body
- support
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to a degradable prostate stent, which comprises a meshed cylindrical stent main body, wherein the stent main body is made from a degradable high polymer material. The degradable prostate stent disclosed by the invention has the beneficial effects that since the stent main body is made from the degradable high polymer material, the degradable prostate stent can conduct conservative treatment on some patients with prostatitis, and the stent is introduced to the location of enlarged prostate and then the stent is expanded for supporting the location of enlarged prostate; moreover, the device, which is degradable in human body within a certain time, is unnecessary to be taken out by special operations, so that pain in patients is relieved, and medical resources are saved at the same time; and in addition, the degradable stent designed by the invention, which can flow out along with urine, is safe and reliable.
Description
Technical field
The invention belongs to technical field of medical equipment, be specifically related to a kind of degradable prostate bracket.
Background technology
Benign prostatic hyperplasia (benignprostatichyperplasiaBPH) is elderly men commonly encountered diseases, is a kind of PD.Along with aged tendency of population develops, sickness rate rises year by year.Domestic relevant information is added up, and the sickness rate of 50 years old male is more than 50%, up to 90% during by 80 years old.The sickness rate of BPH increases day by day, has now become the modal disease of Urology Surgery, owing to sickness rate is high, Quality of Life is serious, one for the treatment of emphasis being always up clinical research.Raising due to medical level, the patients with benign prostate hyperplasia at the advanced age merging the internal organs underlying diseases such as the heart, brain, lung, kidney also progressively increases, for high-risk benign prostatic hyperplasia patients, owing to operation risk is big, Urology Surgery doctor can adopt treatment means limited, often adopt expectant treatment method, such as long term indwelling catheter or long-term bladder stoma.
The method for the treatment of BPH currently mainly has: Drug therapy, Suprapubic Prostatectomy, Transurethral prostatic electroresection A, per urethra laser ablation art, high intensity focused ultrasound treating, per urethra prostate sacculus dilation operation, cystostomy, prostate supporting way etc..
The goldstandard being wherein primary treatment BPH with the Therapeutic Method of Transurethral prostatic electroresection A with the advantage in itself, but this kind of Therapeutic Method is traumatic treatment, mainly through the excision prostatic a part of body of gland of patient and then expansion urethra, realize the purpose for the treatment of, this kind of mode wound is big, the body constitution of patient is required higher, for some gerontal patients, it is difficult to bear the wound that this kind of mode causes, there is bigger risk, simultaneously because otch is bigger, the time of surgical staff operation is also longer, further increase the misery of operation receiveing person, and operative treatment has a big risk, easily it is with material sequela to patient, show through statistics, there is the patient of 10% after being treated surgically, deferent duct suffers damage in various degree.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides a kind of degradable prostate bracket, by being arranged to degradable macromolecular material through rack body, it is possible to carry out expectant treatment for some prostate patients, support is imported to the prostate position of enlargement, then decontrol and be supported, and this device certain time and degradable in human body, it is not necessary to special operation is taken out, it is possible to alleviate the misery of patient, simultaneously, it is also possible to saved medical resource；It addition, flow out with urine after the biodegradable stent degraded of present invention design, safe and reliable.
The technical solution adopted in the present invention is: a kind of degradable prostate bracket, including: the rack body of net type tubular, described rack body is made up of degradable macromolecular material.
The further optimization of technical solution of the present invention, described degradable macromolecular material is one or more in polylactic acid (PLA), polycaprolactone (PCL), Poly(D,L-lactide-co-glycolide (PLGA), polyhydroxyalkanoate (PHA) or polyacrylate (PEA).
The further optimization of technical solution of the present invention, described rack body includes the first support and the second support, is connected by a connecting filament between described first support and described second support.
The further optimization of technical solution of the present invention, the lateral wall of described rack body is arranged at intervals with a series of depression and projection, described depression and projection in order to be fixed in body of prostate by rack body.
The further optimization of technical solution of the present invention, described rack body is coated with the biocompatibility coating formed by silicon or PTFE.
The further optimization of technical solution of the present invention, described rack body is made up of ferrous alloy material, and the surface of described rack body is coated with degradable macromolecular material.
The invention have the benefit that and rack body is arranged to degradable macromolecular material, after support imports to the prostate position that patient is loose, mechanical property can be kept in 12 months after importing human body, patient is made to recover normal physiological function, after reaching the regular hour, rack body can be degraded automatically, medical treatment taking-up need not be carried out again, alleviate the misery of patient, also save medical resource simultaneously, pure Biodegradable material is easier to realize micromolecular degraded, the support of residual will be made to penetrate in the process of degraded relative to the alloy bracket of iron-based to recognize in skin.It addition, rack body is arranged to the material of ferroalloy, what it was main realizes method is: prepare degradable macromolecule coating on ferrous alloy surface, and the acidic micro-environment produced by the degraded of this polymeric coating layer improves the gas-evolving electrodes speed of ferrous alloy.
Accompanying drawing explanation
Fig. 1 is the structural representation of the degradable prostate bracket of the present invention；
Fig. 2 is the present invention degradable prostate bracket schematic diagram with fixed structure.
In figure: 1, rack body；2, mesh sides；3, depression；4, protruding.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly, technical scheme will be described in detail below.Obviously, described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, other embodiments all that those of ordinary skill in the art are obtained under the premise not making creative work, broadly fall into the scope that the present invention protects.
Embodiment 1
As it is shown in figure 1, the invention provides a kind of degradable prostate bracket, including: the rack body 1 of net type tubular, described rack body 1 is by degradable macromolecular material.Described iron is pure iron, Fe-Mn, Fe-Mn-C, Fe-Mn-S, Fe-Mn-Pt alloy system and other biodegradable ferrous alloy；Described degradable macromolecular material is a kind of or arbitrarily multiple combination in the polylactic acid (PLA) containing ester bond, polycaprolactone (PCL), Poly(D,L-lactide-co-glycolide (PLGA), polyhydroxyalkanoate (PHA) or polyacrylate (PEA).
The matrix of prostate bracket is completely the same with existing coronary artery bracket matrix, we are by by arranging the rack body 1 being made up of degradable high polymer material, the practicality of support can be increased, the use time of extending bracket, and in the procedure decomposed, patient is more safe, additionally, macromolecular material resolves into little molecule object discharges with urine, human body will not be caused damage.
Embodiment 2
On the basis of embodiment 1, ferrous alloy is had to make prostate bracket, outer surface at support covers degradable macromolecular material, this macromolecular material is degraded in physiological environment, wherein ester bond degraded produces have acid carboxylic group, the pH value making local microenvironment declines, thus the gas-evolving electrodes speed of ferrous alloy can be improved, increases ferrous alloy corrosion/degradation speed in human physiological environment.
Embodiment 3
The ferroalloy rack body 1 of net type tubular, the surface of described rack body 1 is coated with degradable macromolecular material, described rack body 1 includes the first support and the second support, (not shown corresponding accompanying drawing) is connected by a connecting filament between described first support and described second support, this is designed to facilitate the fixing of rack body 1, and connecting filament will not make patient produce foreign body sensation through sphincter, connecting filament in this technical scheme preferred is degradable material, after this support is imported human body, second support functions only as fixing effect, after first support is delivered to the prostate position of human body, connecting filament can be degraded in a short period of time, so that the second support excretes.
Embodiment 4
On the basis of embodiment 1 as shown in Figure 2, the lateral wall of described rack body 1 is arranged at intervals with a series of depression 3 and protruding 4, described depression 3 and protruding 4 is in order to be fixed in body of prostate by rack body 1, it is possible to prevent rack body 1 from moving along with the impact of liquid.
In order to prevent the human body rejection to prostate bracket, being coated with the biocompatibility coating formed by silicon or PTFE on described rack body 1 can increase the adaptability of support.
The above; being only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, any those familiar with the art is in the technical scope that the invention discloses; change can be readily occurred in or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with scope of the claims.
Claims (6)
1. a degradable prostate bracket, it is characterised in that including: the rack body of net type tubular, described rack body is made up of degradable macromolecular material.
2. degradable prostate bracket according to claim 1, it is characterised in that: described degradable macromolecular material is one or more in polylactic acid, polycaprolactone, Poly(D,L-lactide-co-glycolide, polyhydroxyalkanoate or polyacrylate.
3. degradable prostate bracket according to claim 1, it is characterised in that: described rack body includes the first support and the second support, is connected by a connecting filament between described first support and described second support.
4. degradable prostate bracket according to claim 1, it is characterised in that: the lateral wall of described rack body is arranged at intervals with a series of depression and projection, described depression and projection in order to be fixed in body of prostate by rack body.
5. degradable prostate bracket according to claim 1, it is characterised in that: described rack body is coated with the biocompatibility coating formed by silicon or PTFE.
6. degradable prostate bracket according to claim 1, it is characterised in that: described rack body is made up of ferrous alloy material, and the surface of described rack body is coated with degradable macromolecular material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610034140.XA CN105708588A (en) | 2016-01-19 | 2016-01-19 | Degradable prostate stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610034140.XA CN105708588A (en) | 2016-01-19 | 2016-01-19 | Degradable prostate stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105708588A true CN105708588A (en) | 2016-06-29 |
Family
ID=56147174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610034140.XA Pending CN105708588A (en) | 2016-01-19 | 2016-01-19 | Degradable prostate stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105708588A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110141408A (en) * | 2019-06-10 | 2019-08-20 | 中国医科大学附属盛京医院 | A degradable composite urethral stent |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050113748A1 (en) * | 1994-07-13 | 2005-05-26 | Marian Devonec | Therapeutic device for the selective cytoreduction treatment of an obstruction in a natural lumen or passage of the human or animal body |
| US20060064120A1 (en) * | 2004-09-17 | 2006-03-23 | Levine Andy H | Atraumatic gastrointestinal anchor |
| CN102228721A (en) * | 2011-06-09 | 2011-11-02 | 中国科学院金属研究所 | Degradable coronary stent and manufacturing method thereof |
| CN102551932A (en) * | 2010-12-16 | 2012-07-11 | 太雄医疗器株式会社 | Urethral stent for the prostate |
| CN102697587A (en) * | 2012-06-25 | 2012-10-03 | 吕文峰 | Biodegradable bracket and preparation method thereof |
| CN103607977A (en) * | 2011-06-07 | 2014-02-26 | 刘青 | Hybrid polymer stent fabricated by a non-laser cut fabrication method |
| CN105073065A (en) * | 2012-09-18 | 2015-11-18 | 鲁昂大学医学中心 | urethral prosthesis |
-
2016
- 2016-01-19 CN CN201610034140.XA patent/CN105708588A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050113748A1 (en) * | 1994-07-13 | 2005-05-26 | Marian Devonec | Therapeutic device for the selective cytoreduction treatment of an obstruction in a natural lumen or passage of the human or animal body |
| US20060064120A1 (en) * | 2004-09-17 | 2006-03-23 | Levine Andy H | Atraumatic gastrointestinal anchor |
| CN102551932A (en) * | 2010-12-16 | 2012-07-11 | 太雄医疗器株式会社 | Urethral stent for the prostate |
| CN103607977A (en) * | 2011-06-07 | 2014-02-26 | 刘青 | Hybrid polymer stent fabricated by a non-laser cut fabrication method |
| CN102228721A (en) * | 2011-06-09 | 2011-11-02 | 中国科学院金属研究所 | Degradable coronary stent and manufacturing method thereof |
| CN102697587A (en) * | 2012-06-25 | 2012-10-03 | 吕文峰 | Biodegradable bracket and preparation method thereof |
| CN105073065A (en) * | 2012-09-18 | 2015-11-18 | 鲁昂大学医学中心 | urethral prosthesis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110141408A (en) * | 2019-06-10 | 2019-08-20 | 中国医科大学附属盛京医院 | A degradable composite urethral stent |
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160629 |
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| RJ01 | Rejection of invention patent application after publication |