CN105477600A - Drug for treating prolonged lochiorrhea and preparation method thereof - Google Patents
Drug for treating prolonged lochiorrhea and preparation method thereof Download PDFInfo
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- CN105477600A CN105477600A CN201510949115.XA CN201510949115A CN105477600A CN 105477600 A CN105477600 A CN 105477600A CN 201510949115 A CN201510949115 A CN 201510949115A CN 105477600 A CN105477600 A CN 105477600A
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Abstract
The invention discloses a drug for treating prolonged lochiorrhea and a preparation method thereof. The drug is mainly prepared from Wedelia wallichii less, Herba portulacae, motherwort, Radix rubiae, black soybean, Angelica sinensis, Colla corii asini, Ligusticum wallichii, Salvia miltiorrhiza, palm bark, black sesame, Argrimonia pilosa, plant soot, Saururus chinensis, pollen typhae, Rhizoma drynariae, Polygonum multiflorum, Sanguisorba officinalis, Herba pteridis multifidae, Chinese leek root, peach kernel, baked ginger, pseudo-ginseng, hawthorn and Rhizoma corydalis according to a certain weight proportion. The drug has functions of tonifying kidney and nourishing blood, cooling blood and stopping bleeding and regulating menstruation and stopping pain, and is quick in action, good in treatment effect and free of recurrence when being used for treating prolonged lochiorrhea.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of prolonged lochiorrhea and preparation method thereof, belong to the field of Chinese medicines.
Technical background
After prolonged lochiorrhea refers to that Placenta Hominis is given birth to, the turbid liquid of remaining blood in uterus continue more than 20 days still dripping unclean.The traditional Chinese medical science then thinks the many and deficiency-weakness of spleen-QI of prolonged lochiorrhea, and stagnation of blood stasis is relevant.Because western medicine side effect is large, therefore there is great demand to the Chinese medicine of effectively treating prolonged lochiorrhea in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment prolonged lochiorrhea, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment prolonged lochiorrhea.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Herba Wedeliae Wallichii, Herba Portulacae, Herba Leonuri, Radix Rubiae, Semen sojae atricolor, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Chuanxiong, Rhizoma Cimicifugae, Folium Artemisiae Argyi, Radix Salviae Miltiorrhizae, Radix Lespedezae Buergeri, Rhizoma Sparganii, Herba Selaginellae, Fibra Trachycarpi, Semen Sesami Nigrum, Herba Agrimoniae, Pulvis Fumi Carbonisatus, Rhizoma Saururi (Herba Saururi), Pollen Typhae, Rhizoma Drynariae, Radix Polygoni Multiflori, Radix Sanguisorbae, Herba Pteridis Multifidae, Radix et Bulbus Allii tuberosi, Semen Persicae, Rhizoma Zingiberis Preparatum, Radix Notoginseng, Fructus Crataegi, Rhizoma Corydalis medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat prolonged lochiorrhea.Wherein select Herba Wedeliae Wallichii to be because it is sweet in flavor and warm in property, enrich blood, active function, eliminate-poverty blood, puerperal hemorrhea, hysteromyoma, amenorrhea.Select Herba Portulacae to be because its nature and flavor acid, cold, enter large intestine, liver, spleen channel, have heat-clearing and toxic substances removing, the function of loose blood detumescence, controls hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, scrofula.Select Herba Leonuri to be that cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia because its nature and flavor are worked hard, control and Lou have difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Radix Rubiae is selected to be because its nature and flavor are bitter, cold, there is cooling blood for hemostasis, the function that blood stasis dispelling stimulates the menstrual flow, control haematemesis, epistaxis, metrorrhagia, traumatic hemorrhage, stasis blocking amenorrhea, arthralgia, tumbling and swelling.Select Semen sojae atricolor to be because its property bitter but sweet flavor, flat, enter spleen, kidney channel, invigorate blood circulation, diuretic, dispel the wind, the function of removing toxic substances, swelling of harnessing the river is full, pathogenic wind-toxic beriberi, jaundice edema, migratory arthralgia clonic spasm of the muscle, puerperal puerperal tetanus, locked mouth, carbuncle sore tumefacting virus; Separate poison of drug.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Colla Corii Asini to be that enter lung, liver, kidney channel, have nourishing YIN and supplementing blood, antiabortive function, controls blood deficiency, cough due to consumptive disease because its nature and flavor are sweet flat, haematemesis, epistaxis, to have blood in stool, menoxenia, metrorrhagia, controls leakage.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Rhizoma Cimicifugae is selected to be because the sweet pungent micro-hardship of its nature and flavor, cool, enter lung, spleen, stomach warp, have yang invigorating, deliver, rash, the function of removing toxic substances, controls seasonal epidemic pathogens epidemic disease labor, headache cold and heat, laryngalgia, aphtha scar, and macule is not saturating, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women's metrorrhagia and leukorrhagia, uterus drops, carbuncle sore tumefacting virus.Folium Artemisiae Argyi is because its nature and flavor are bitter, and pungent, temperature, enters spleen, liver, kidney channel, reasonable QI and blood, and by cold-damp, warming the meridian, hemostasis, antiabortive function, controls trusted subordinate's cold type of pain, and convulsion of having loose bowels, chronic dysentery, tells nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have blood circulation and promoting silt, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina pectoris, menoxenia, dysmenorrhea, and to close, metrorrhagia leukorrhagia ， mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Radix Lespedezae Buergeri to be that temperature, enters lung, spleen two warp, have and induce sweat, reduce phlegm, dampness removing, the function of invigorating blood circulation because its nature and flavor are bitter, the wind that cures the wound generates heat, women's blood stasis, stomachache, metrorrhagia, erysipelas.Select Rhizoma Sparganii to be because its nature and flavor toil, flat, enter liver, spleen channel, have removing blood stasis, circulation of qi promoting, removing food stagnancy, the function ， Zhi lumps in the chest and abdomen of pain relieving, the solidifying band of QI and blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, and traumatic injury, skin ulcer swells hard.Herba Selaginellae is selected to be that flat, GUIXIN, heart channel, have the function of promoting blood circulation to restore menstrual flow, controls amenorrhea dysmenorrhea ， mass in the abdomen mass in the abdomen, injury from falling down because its nature and flavor are pungent.Fibra Trachycarpi is selected to be because its nature and flavor are bitter, puckery, flat, enter liver, spleen, large intestine channel, have anastaltic function, control haematemesis, epistaxis, have blood in stool, stranguria with blood, hematuria, dysentery, metrorrhagia, leukorrhagia, incised wound, scabies.Select Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, have invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Select Herba Agrimoniae to be because its nature and flavor toil, flat, enter lung, liver, spleen channel, have hemostasis, the function of stomach invigorating, controls spitting of blood, and spit blood, hematuria, has blood in stool, dysentery, bleeding not during menses, and impairment caused by overstrain takes off power, carbuncle, traumatic injury, wound hemorrhage.Pulvis Fumi Carbonisatus is selected to be that temperature, enter liver, lung, stomach warp, have hemostasis, the function of removing food stagnancy, controls haematemesis, and epistaxis is had blood in stool, metrorrhagia, and leukorrhagia rushes down, food stagnation, all skin ulcers of throat dispute because its nature and flavor are pungent.Select Rhizoma Saururi (Herba Saururi) to be because its nature and flavor are sweet, pungent, cold, return lung, urinary bladder channel, have eliminating damp-heat, detumescence, the function of removing toxic substances, harnesses the river swollen, beriberi, jaundice, stranguria with turbid discharge, leukorrhagia, carbuncle, treats poison.Select Pollen Typhae to be because its nature and flavor are sweet arduous, cool, enter liver, heart channel, have cooling blood for hemostasis, the function of activating blood circulation and dissipating blood stasis, raw with controlling amenorrhea stomachache, postpartum stagnation is had a pain, and falls that to flutter blood vexed, furuncle toxic swelling, fries black emesis blood, epistaxis, metrorrhagia, rush down blood, hematuria, dysentery, leukorrhagia, external treatment congenital deformity of the tongue, aphtha, Ting discharging ear, hemorrhage in ear, uncontrolled urination is itched.Rhizoma Drynariae is selected to be that temperature, enters liver, kidney channel, have the kidney invigorating, invigorate blood circulation, the function of hemostasis, control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus because its nature and flavor are bitter.Radix Polygoni Multiflori is selected to be that tepor, enters liver, kidney channel, have tonifying liver, kidney tonifying, nourish blood, the function of dispeling the wind because its property bitter but sweet flavor is puckery, control hepatic and renal YIN deficiency, sending out must be early white, and blood deficiency is dizzy, and waist knee joint is weak, and muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Select Radix Sanguisorbae to be because of its nature and flavor picric acid, to tremble with fear, enter liver, large intestine channel, have cooling blood for hemostasis, the function of heat-clearing and toxic substances removing, controls haematemesis, epistaxis, dysentery, collapse, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.Herba Pteridis Multifidae is selected to be because its nature and flavor are light, micro-hardship, cold, enter kidney, stomach two warp, have clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, the function of subduing swelling and detoxicating, control icterohepatitis, enteritis, bacillary dysentery, stranguria with turbid discharge, leukorrhagia, spit blood, epistaxis, have blood in stool, hematuria, tonsillitis, parotitis, carbuncle sore tumefacting virus, eczema.Select Radix et Bulbus Allii tuberosi to be because its nature and flavor are pungent, temperature, return spleen, stomach warp, have warming middle-JIAO, circulation of qi promoting, the function of dissipating blood stasis, controls the thoracic obstruction, dyspeptic abdominal distention, leucorrhea with red and white discharge, spits blood, epistaxis, tinea skin ulcer, traumatic injury.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select Rhizoma Zingiberis Preparatum to be because its nature and flavor are pungent, heat, return spleen, stomach, kidney, the heart, lung meridian, have warming spleen and stomach for dispelling cold, the function of warming the meridian for stopping bleeding, controls Deficiency and coldness of spleen and stomach, and stomachache is vomited and diarrhoea, and tell nosebleed metrorrhagia, yang deficiency is lost blood.Select Radix Notoginseng to be because its property sweet and slightly bitter taste, temperature, enters liver, stomach, large intestine channel, has hemostasis, dissipating blood stasis, and detumescence, the function of analgesic therapy, controls haematemesis, hemoptysis, and epistaxis is had blood in stool, dysentery, metrorrhagia, mass in the abdomen, puerperal blood faints, and retention of lochia falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.Select Fructus Crataegi be because its nature and flavor acid sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji ， mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate.Rhizoma Corydalis is selected to be that temperature, enter liver, stomach warp, invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, the function of pain relieving, controls all pains of trusted subordinate's waist knee joint, menoxenia ， mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury because its nature and flavor are worked hard.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Herba Wedeliae Wallichii 15-25 gram, Herba Portulacae 10-15 gram, Herba Leonuri 12-18 gram, Radix Rubiae 8-12 gram, Semen sojae atricolor 10-15 gram, Radix Angelicae Sinensis 15-25 gram, Colla Corii Asini 12-18 gram, Rhizoma Chuanxiong 10-15 gram, Rhizoma Cimicifugae 10-15 gram, Folium Artemisiae Argyi 10-15 gram, Radix Salviae Miltiorrhizae 8-12 gram, Radix Lespedezae Buergeri 15-25 gram, Rhizoma Sparganii 8-12 gram, Herba Selaginellae 10-15 gram, Fibra Trachycarpi 10-15 gram, Semen Sesami Nigrum 15-25 gram, Herba Agrimoniae 10-15 gram, Pulvis Fumi Carbonisatus 8-12 gram, Rhizoma Saururi (Herba Saururi) 8-12 gram, Pollen Typhae 10-15 gram, Rhizoma Drynariae 15-25 gram, Radix Polygoni Multiflori 15-25 gram, Radix Sanguisorbae 10-15 gram, Herba Pteridis Multifidae 10-15 gram, Radix et Bulbus Allii tuberosi 8-12 gram, Semen Persicae 12-18 gram, Rhizoma Zingiberis Preparatum 12-18 gram, Radix Notoginseng 10-15 gram, Fructus Crataegi 10-15 gram, Rhizoma Corydalis 10-15 gram.
Be preferably
Herba Wedeliae Wallichii 20 grams, Herba Portulacae 12 grams, Herba Leonuri 15 grams, 10 grams, Radix Rubiae, Semen sojae atricolor 12 grams, Radix Angelicae Sinensis 20 grams, 15 grams, Colla Corii Asini, Rhizoma Chuanxiong 12 grams, Rhizoma Cimicifugae 12 grams, Folium Artemisiae Argyi 12 grams, Radix Salviae Miltiorrhizae 10 grams, Radix Lespedezae Buergeri 20 grams, Rhizoma Sparganii 10 grams, Herba Selaginellae 12 grams, Fibra Trachycarpi 12 grams, Semen Sesami Nigrum 20 grams, Herba Agrimoniae 12 grams, Pulvis Fumi Carbonisatus 10 grams, Rhizoma Saururi (Herba Saururi) 10 grams, Pollen Typhae 12 grams, Rhizoma Drynariae 20 grams, Radix Polygoni Multiflori 20 grams, Radix Sanguisorbae 12 grams, Herba Pteridis Multifidae 12 grams, Radix et Bulbus Allii tuberosi 10 grams, 15 grams, Semen Persicae, Rhizoma Zingiberis Preparatum 15 grams, Radix Notoginseng 12 grams, Fructus Crataegi 12 grams, Rhizoma Corydalis 12 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Herba Wedeliae Wallichii: autumn excavates, cleans, dries;
2, Herba Portulacae: pick clean impurity, removing undesirable root, slightly moisten with water, cutting is dried;
3, Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
4, Radix Rubiae: removing impurity, cleans, runs through, cut sheet or section, and dry, sieve removes chip;
5, Semen sojae atricolor: pick clean impurity, dry;
6, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
7, Colla Corii Asini: smash use to pieces;
8, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
9, Rhizoma Cimicifugae: pick decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
10, Folium Artemisiae Argyi: get clean Folium Artemisiae Argyi and put in pot to fry with high heat to seventy percent and turn black, spray with vinegar, mix thoroughly and cross iron wire sieve afterwards, person heavily fries thoroughly, takes out, dries in the air cool, prevent resume combustion, store after three days, every Folium Artemisiae Argyi 100 jin, with vinegar 15 jin;
11, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
12, Radix Lespedezae Buergeri: after excavating, removes rough bark, and section, dries;
13, Rhizoma Sparganii: pick clean impurity, be soaked in water, pull out and run through, section, dries;
14, Herba Selaginellae: get crude drug, removing residual fibrous root, impurity, clean, slightly dry in the air, cutting, dry;
15, Fibra Trachycarpi: get clean Fibra Trachycarpi, puts in pot, covers the pot that a bore is slightly little, a piece of paper pasted by pot, and two pots of joint yellow mud sternly seal, and it is that coke yellow is ceased fire that low baking temperature is calcined to blank sheet of paper, waits cold taking-up;
16, Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
17, Herba Agrimoniae: removing impurity undesirable root, cleans, runs through, cut off, dry;
18, Pulvis Fumi Carbonisatus: scraping in the bottom of a pan or chimney of burning faggot, sieves decontamination with dusting cover, puts in bottle and use;
19, Rhizoma Saururi (Herba Saururi): removing impurity, clean, cutting, dries;
20, Pollen Typhae: rub broken caking, sieve, removing impurity;
21, Rhizoma Drynariae: remove sediment contamination, cleans, slightly soaks, run through, and section, dries;
22, Radix Polygoni Multiflori: pick decontamination, cleans, saturating with blister to eighty per cant, pulls out, and profit is even to inside and outside humidity, and section or dice, dry;
23, Radix Sanguisorbae: pick decontamination, washes, and slightly soaks, and runs through, and is cut into sheet, dries;
24, Herba Pteridis Multifidae: remove surperficial earth, cleans, dries;
25, Radix et Bulbus Allii tuberosi: clean, using fresh herb or dry;
26, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
27, Rhizoma Zingiberis Preparatum: get dried ginger slice or sheet, fries to heaving, surperficial sepia;
28, Radix Notoginseng: pick clean impurity, smash to pieces, grinds or runs through rear section into powder and dry;
29, Fructus Crataegi charcoal: get and pick clean Fructus Crataegi, puts in pot and fries to outside coke black sustainability with high heat, and spray clear water, takes out, dry;
30, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes.
Two, prepare
1, the Herba Wedeliae Wallichii of described weight, Herba Portulacae, Herba Leonuri, Radix Rubiae, Semen sojae atricolor, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Chuanxiong, Rhizoma Cimicifugae, Folium Artemisiae Argyi, Radix Salviae Miltiorrhizae, Radix Lespedezae Buergeri, Rhizoma Sparganii, Herba Selaginellae, Fibra Trachycarpi, Semen Sesami Nigrum, Herba Agrimoniae, Pulvis Fumi Carbonisatus, Rhizoma Saururi (Herba Saururi), Pollen Typhae, Rhizoma Drynariae, Radix Polygoni Multiflori, Radix Sanguisorbae, Herba Pteridis Multifidae, Radix et Bulbus Allii tuberosi, Semen Persicae, Rhizoma Zingiberis Preparatum, Radix Notoginseng, Fructus Crataegi, Rhizoma Corydalis are put into decocting container, add water 8 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
3, by twice decoction liquor mixing and stirring and get final product, 4 doses are divided into take.
In prescription, Rhizoma Drynariae has the kidney invigorating, invigorates blood circulation, and the function of hemostasis is monarch drug; Radix Polygoni Multiflori tonifying liver, kidney tonifying, nourishes blood, and dispels the wind; Semen Sesami Nigrum has invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, the two is ministerial drug, and three taste medicines play the kidney invigorating jointly, nourish blood, hemostasis, the effect of moisturizing, treatment prolonged lochiorrhea effect is comprehensive, and with the kidney invigorating, nourish blood, hemostasis is that master can be effected a permanent cure, Radix Angelicae Sinensis has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, and the function of moisturizing laxation is adjuvant drug, Herba Wedeliae Wallichii is enriched blood, and the function of invigorating blood circulation, for making medicine, is take stopgap measures with all medicines of remainder.
Medicine of the present invention has kidney-replenishing blood-nourishing, heat-clearing and toxic substances removing, and the function restored menstrual flow and invigorated blood circulation, is used for the treatment of prolonged lochiorrhea, short treating period, instant effect, non-relapse after healing.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept prolonged lochiorrhea out-patient totally 32 examples for medical treatment.
2, diagnostic criteria
Lochia, amount is many, and color is light red, and matter is rare clearly, odorless, pale complexion, mental fatigue with loss of appetite, empty and bearing-down sensation of the lower abdomen, and large loose stool is thin, light red tongue, white and thin fur, and moderate pulse is weak.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 7 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: prolonged lochiorrhea transference cure, body constitution recovers normal, recovery from illness;
Take a turn for the better: patient's stomachache, dripping urine endlessly phenomenon alleviate, and prolonged lochiorrhea symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy prolonged lochiorrhea patient 32 example of the present invention, effective 28 examples of result, obvious effective rate is 87.5%, and take a turn for the better 3 examples, and improvement rate is 9.38%, and invalid 1 example, total effective rate is 96.88%.
Claims (3)
1. treat a medicine for prolonged lochiorrhea, it is characterized in that: it is made up of the crude drug in following weight range:
Herba Wedeliae Wallichii 15-25 gram, Herba Portulacae 10-15 gram, Herba Leonuri 12-18 gram, Radix Rubiae 8-12 gram, Semen sojae atricolor 10-15 gram, Radix Angelicae Sinensis 15-25 gram, Colla Corii Asini 12-18 gram, Rhizoma Chuanxiong 10-15 gram, Rhizoma Cimicifugae 10-15 gram, Folium Artemisiae Argyi 10-15 gram, Radix Salviae Miltiorrhizae 8-12 gram, Radix Lespedezae Buergeri 15-25 gram, Rhizoma Sparganii 8-12 gram, Herba Selaginellae 10-15 gram, Fibra Trachycarpi 10-15 gram, Semen Sesami Nigrum 15-25 gram, Herba Agrimoniae 10-15 gram, Pulvis Fumi Carbonisatus 8-12 gram, Rhizoma Saururi (Herba Saururi) 8-12 gram, Pollen Typhae 10-15 gram, Rhizoma Drynariae 15-25 gram, Radix Polygoni Multiflori 15-25 gram, Radix Sanguisorbae 10-15 gram, Herba Pteridis Multifidae 10-15 gram, Radix et Bulbus Allii tuberosi 8-12 gram, Semen Persicae 12-18 gram, Rhizoma Zingiberis Preparatum 12-18 gram, Radix Notoginseng 10-15 gram, Fructus Crataegi 10-15 gram, Rhizoma Corydalis 10-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Herba Wedeliae Wallichii 20 grams, Herba Portulacae 12 grams, Herba Leonuri 15 grams, 10 grams, Radix Rubiae, Semen sojae atricolor 12 grams, Radix Angelicae Sinensis 20 grams, 15 grams, Colla Corii Asini, Rhizoma Chuanxiong 12 grams, Rhizoma Cimicifugae 12 grams, Folium Artemisiae Argyi 12 grams, Radix Salviae Miltiorrhizae 10 grams, Radix Lespedezae Buergeri 20 grams, Rhizoma Sparganii 10 grams, Herba Selaginellae 12 grams, Fibra Trachycarpi 12 grams, Semen Sesami Nigrum 20 grams, Herba Agrimoniae 12 grams, Pulvis Fumi Carbonisatus 10 grams, Rhizoma Saururi (Herba Saururi) 10 grams, Pollen Typhae 12 grams, Rhizoma Drynariae 20 grams, Radix Polygoni Multiflori 20 grams, Radix Sanguisorbae 12 grams, Herba Pteridis Multifidae 12 grams, Radix et Bulbus Allii tuberosi 10 grams, 15 grams, Semen Persicae, Rhizoma Zingiberis Preparatum 15 grams, Radix Notoginseng 12 grams, Fructus Crataegi 12 grams, Rhizoma Corydalis 12 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Herba Wedeliae Wallichii: autumn excavates, cleans, dries;
(2) Herba Portulacae: pick clean impurity, removing undesirable root, slightly moisten with water, cutting is dried;
(3) Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
(4) Radix Rubiae: removing impurity, cleans, runs through, cut sheet or section, and dry, sieve removes chip;
(5) Semen sojae atricolor: pick clean impurity, dry;
(6) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(7) Colla Corii Asini: smash use to pieces;
(8) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
(9) Rhizoma Cimicifugae: pick decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
(10) Folium Artemisiae Argyi: get clean Folium Artemisiae Argyi and put in pot to fry with high heat to seventy percent and turn black, spray with vinegar, mix thoroughly and cross iron wire sieve afterwards, person heavily fries thoroughly, takes out, dries in the air cool, prevent resume combustion, store after three days, every Folium Artemisiae Argyi 100 jin, with vinegar 15 jin;
(11) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(12) Radix Lespedezae Buergeri: after excavating, removes rough bark, and section, dries;
(13) Rhizoma Sparganii: pick clean impurity, be soaked in water, pull out and run through, section, dries;
(14) Herba Selaginellae: get crude drug, removing residual fibrous root, impurity, clean, slightly dry in the air, cutting, dry;
(15) Fibra Trachycarpi: get clean Fibra Trachycarpi, puts in pot, covers the pot that a bore is slightly little, a piece of paper pasted by pot, and two pots of joint yellow mud sternly seal, and it is that coke yellow is ceased fire that low baking temperature is calcined to blank sheet of paper, waits cold taking-up;
(16) Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
(17) Herba Agrimoniae: removing impurity undesirable root, cleans, runs through, cut off, dry;
(18) Pulvis Fumi Carbonisatus: scraping in the bottom of a pan or chimney of burning faggot, sieves decontamination with dusting cover, puts in bottle and use;
(19) Rhizoma Saururi (Herba Saururi): removing impurity, clean, cutting, dries;
(20) Pollen Typhae: rub broken caking, sieve, removing impurity;
(21) Rhizoma Drynariae: remove sediment contamination, cleans, slightly soaks, run through, and section, dries;
(22) Radix Polygoni Multiflori: pick decontamination, cleans, saturating with blister to eighty per cant, pulls out, and profit is even to inside and outside humidity, and section or dice, dry;
(23) Radix Sanguisorbae: pick decontamination, washes, and slightly soaks, and runs through, and is cut into sheet, dries;
(24) Herba Pteridis Multifidae: remove surperficial earth, cleans, dries;
(25) Radix et Bulbus Allii tuberosi: clean, dry;
(26) Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
(27) Rhizoma Zingiberis Preparatum: get dried ginger slice or sheet, fries to heaving, surperficial sepia;
(28) Radix Notoginseng: pick clean impurity, smash to pieces, grinds or runs through rear section into powder and dry;
(29) Fructus Crataegi: get and pick clean Fructus Crataegi, puts in pot and fries to outside coke black sustainability with high heat, and spray clear water, takes out, dry;
(30) Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
(2) prepare
(1) described Herba Wedeliae Wallichii, Herba Portulacae, Herba Leonuri, Radix Rubiae, Semen sojae atricolor, Radix Angelicae Sinensis, Colla Corii Asini, Rhizoma Chuanxiong, Rhizoma Cimicifugae, Folium Artemisiae Argyi, Radix Salviae Miltiorrhizae, Radix Lespedezae Buergeri, Rhizoma Sparganii, Herba Selaginellae, Fibra Trachycarpi, Semen Sesami Nigrum, Herba Agrimoniae, Pulvis Fumi Carbonisatus, Rhizoma Saururi (Herba Saururi), Pollen Typhae, Rhizoma Drynariae, Radix Polygoni Multiflori, Radix Sanguisorbae, Herba Pteridis Multifidae, Radix et Bulbus Allii tuberosi, Semen Persicae, Rhizoma Zingiberis Preparatum, Radix Notoginseng, Fructus Crataegi, Rhizoma Corydalis are put into decocting container, add water 8 times amount, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring and get final product, 4 doses are divided into take.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267021A (en) * | 2016-09-30 | 2017-01-04 | 四川兴聚焦医药科技有限责任公司 | A kind of Chinese medicine composition treating QIXUELIANGXU type decubital ulcer and preparation method thereof |
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2015
- 2015-12-18 CN CN201510949115.XA patent/CN105477600A/en not_active Withdrawn
Non-Patent Citations (2)
| Title |
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| 中国药材公司: "《中国民间单验方》", 31 October 1994, 科学出版社 * |
| 张玉波等: "简述药物流产后恶露不净的辨证论治", 《光明中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267021A (en) * | 2016-09-30 | 2017-01-04 | 四川兴聚焦医药科技有限责任公司 | A kind of Chinese medicine composition treating QIXUELIANGXU type decubital ulcer and preparation method thereof |
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