CN105362103A - Quick-drying hand disinfection emulsion - Google Patents
Quick-drying hand disinfection emulsion Download PDFInfo
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- CN105362103A CN105362103A CN201510951822.2A CN201510951822A CN105362103A CN 105362103 A CN105362103 A CN 105362103A CN 201510951822 A CN201510951822 A CN 201510951822A CN 105362103 A CN105362103 A CN 105362103A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Oil, Petroleum & Natural Gas (AREA)
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Abstract
The invention discloses a quick-drying hand disinfection emulsion. The quick-drying hand disinfection emulsion is gelatinous and is prepared from, by mass, 40%-75% of short-chain alcohol, 0.1%-5.0% of cationic bactericide, 0.1%-10.0% of emulsification thickener, 0.1%-10.0% of emollient and the balance water. The quick-drying hand disinfection emulsion is mainly used for sanitary hand disinfection and surgical hand disinfection, has a good disinfection effect and can be prepared at normal temperature through a simple preparation process without heating or special equipment. The prepared emulsion is good in stability and high in drying speed after being used and has a good moistening effect on the skin.
Description
Technical field
the present invention relates to a kind of quick-dry type hand disinfection emulsion.
Background technology
hand-wrist bones gel great majority conventional on the market are at present transparent gel shapes; the wetting agent added also only is limited to the polyhydric alcohol, amino acids etc. of good water solubility; these specific diminishing moisture-retainings can not reduce alcohols or cationic disinfectant to the zest of skin, the situation of usually there will be drying after life-time service, chapping.
and emulsion-type gel can add oiliness skin care ingredient conventional in some cosmetics cream; as squalane, Jojoba oil, lanoline etc.; the composition that these skin care ingredients and skin produce voluntarily is similar; one protective layer can be formed on skin after using; supplement the deficiency of skin oil and fat; prevent moisture from evaporating and skin care, farthest protective action is played to hand, reduce the zest because alcohol and cationic germicide produce.
now have emulsion-type disinfecting gel preparation on the market, as good in 3M love tM disposable surgery hand sanitizing fluid, it needs to heat up and homogenizing process at process for preparation, and technique is more complicated, from production cost, time or workload, all have certain difficulty and inconvenience.Zhang Wanguo discloses a kind of emulsion-type gel preparation containing chlorhexidine and ethanol in Chinese patent CN101310702A, is also to stir after needing that all the components except ethanol is heated to 70 DEG C to 80 DEG C to obtain.
Summary of the invention
the object of the invention is to solve the problem that hand-wrist bones gel is common on the market, provide that a kind of moistening effect is good, zest is low, can the quick-dry type hand disinfection emulsion of room temperature preparation.
to achieve the object of the present invention, the present invention adopts technical scheme: a kind of fast-drying type disinfection emulsion, according to mass percent, it is made up of 40%-75% short chain alcohol, 0.1%-5.0% cationic germicide, 0.1%-10.0% emulsifing thickener, 0.1%-10.0% emollient and excess water.
short chain alcohol described in above-mentioned hand-wrist bones emulsion is one or both in ethanol, isopropyl alcohol.
described cationic germicide is one or more in chlorhexidine gluconate, chlorhexidine acetate, poly hexamethylene biguanide, Benzalkonii Chloridum, benzalkonium bromide and benzethonium chloride.
described emulsifing thickener is one or more in polyacrylamide, polyacrylic acid, isoparaffin, fatty alcohol-polyoxyethylene ether, fatty acid ester and fatty alcohol.
described emollient be natural minerals oils and fats, animal oil, Vegetable oil lipoprotein, synthetic ester oil, polyhydric alcohol one or more.
described short chain alcohol is ethanol.
described cationic germicide is one or both in chlorhexidine gluconate, benzethonium chloride, and is medical rank raw material.
described cationic germicide is chlorhexidine gluconate.
described emulsifing thickener is one or more in polyacrylamide, isoparaffin, fatty alcohol-polyoxyethylene ether, fatty alcohol.
described isoparaffin carbon number is 10 to 30.
described isoparaffin carbon number is 10 to 22.
described fatty alcohol-polyoxyethylene ether carbon number is 10 to 30, and ethylene oxide number is 1-50.
described fatty alcohol-polyoxyethylene ether carbon number is 10 to 20, and ethylene oxide number is 1-30.
described fatty alcohol carbon number is 6 to 30.
described fatty alcohol carbon number is preferably 10 to 25.
described emollient is one or more in vaseline, white oil, Jojoba oil, lanoline, squalane, glycerol.
its viscosity at 25 DEG C is 3000cP to 30000cP, and prepares at normal temperatures.
advantage of the present invention is:
the present invention, except having good bactericidal effect, uses rear arm can rapid draing, without the need to drying, substantially reduces the processing time, simultaneously with after can form one protective layer on skin, the deficiency of supplementary skin oil and fat, prevents moisture from evaporating and moistens.Formula of the present invention only need at room temperature be prepared, and without the need to heating up and special equipment, technique is simple, can greatly save Production Time and cost.
Specific embodiments
embodiment 1:
| Sequence number | Formula forms | Mass percent, % |
| 1 | Polyacrylamide | 0.5 |
| 2 | IP 1620 | 2 |
| 3 | Laureth 3 | 1 |
| 4 | Squalane | 3 |
| 5 | Lanoline | 2 |
| 6 | Glycerol | 5 |
| 7 | Ethanol | 60 |
| 8 | Chlorhexidine gluconate | 1 |
| 9 | Water | Surplus |
described in embodiment 1iP1620
being isoparaffin, is the product of Japanese bright dipping.
quick-dry type hand disinfection emulsion prepared by embodiment 1, outward appearance is milky, and Disinfection Effect is good, rapid-curing cutback, and soothing effect is excellent simultaneously, can at room temperature obtain by mix and blend.
embodiment 2:
| Sequence number | Formula forms | Mass percent, % |
| 1 | Sodium polyacrylate | 0.3 |
| 2 | Laureth 7 | 1 |
| 3 | Polyglyceryl fatty acid ester | 2 |
| 4 | Squalane | 1 |
| 5 | Jojoba oil | 3 |
| 6 | Sorbitol | 3 |
| 7 | Ethanol | 50 |
| 8 | Benzethonium chloride | 0.5 |
| 9 | Water | Surplus |
quick-dry type hand disinfection emulsion prepared by embodiment 2, appearance milky white, can obtain by mix and blend under room temperature.
embodiment 3:
| Sequence number | Formula forms | Mass percent, % |
| 1 | Polyacrylamide | 0.6 |
| 2 | 12-tetradecyl alchohol polyoxyethylene ether-3 | 1 |
| 3 | C16-C18 fatty alcohol | 2 |
| 4 | Lanoline | 1 |
| 5 | Butanediol | 3 |
| 6 | C16 isoparaffin | 2 |
| 7 | Ethanol | 30 |
| 8 | Isopropyl alcohol | 30 |
| 9 | Poly hexamethylene biguanide | 1.5 |
| 10 | Water | Surplus |
embodiment 3 with the addition of the skin care ingredient such as lanoline, butanediol, the emulsifing thickener simultaneously added, as C16 isoparaffin,c16-C18
fatty alcohol etc., also have certain skin moistening effect, use that rear skinfeel is good, non-greasy, simultaneously can rapid draing.The emulsion at room temperature obtained according to embodiment 3 is not stratified after being placed on 50 DEG C of baking oven 24h, has good stability.
embodiment 4:
| Sequence number | Formula forms | Mass percent, % |
| 1 | Polyacrylamide | 0.6 |
| 2 | 12-tetradecyl alchohol polyoxyethylene ether-3 | 2.5 |
| 3 | Polyoxyethylene lauryl ether-9 | 3 |
| 4 | Xylitol | 3 |
| 5 | Squalane | 5 |
| 6 | Ethanol | 55 |
| 7 | Isopropyl alcohol | 10 |
| 8 | Benzalkonii Chloridum | 0.5 |
| 9 | Water | Surplus |
the formulation aesthetics that embodiment 4 obtains is milky, uses rear soft handle, glutinous not greasy, not tight, can rapid draing.Preliminary test, under 20 DEG C of test temperatures, stock solution effect reaches the hygienic requirements of hand disinfectant to the kill oncomelania >4.00 of Candida albicans in 0.5 minute.
embodiment 5:
| Sequence number | Formula forms | Mass percent, % |
| 1 | Sodium polyacrylate | 0.3 |
| 2 | Isomerous tridecanol | 3 |
| 3 | Polyoxyethylene lauryl ether-7 | 2 |
| 4 | Stearyl alcohol | 3 |
| 5 | Spermol | 2 |
| 6 | Glycerol | 3 |
| 7 | Isopropyl alcohol | 60 |
| 8 | Chlorhexidine gluconate | 2.0 |
| 9 | Water | Surplus |
embodiment 5 at room temperature can obtain emulsion gel, can rapid draing after using, effective to skin moisturizing, nonirritant.
certain above-described embodiment, only for technical conceive of the present invention and feature are described, its object is to person skilled in the art can be understood content of the present invention and implement according to this, can not limit the scope of the invention with this.All equivalent transformations of doing according to the spirit of main technical schemes of the present invention or modification, all should be encompassed within protection scope of the present invention.
Claims (17)
1. a quick-dry type hand disinfection emulsion, is characterized in that, the mass percent of each component consists of:
(a) 40%-75% short chain alcohol
(b) 0.1%-5.0% cationic germicide
(c) 1%-10.0% emulsifing thickener
(d) 1%-10.0% emollient
(e) water surplus.
2. a kind of quick-dry type hand disinfection emulsion according to claim 1, is characterized in that described short chain alcohol is one or both in ethanol, isopropyl alcohol.
3. a kind of quick-dry type hand disinfection emulsion according to claim 1, is characterized in that described cationic germicide is one or more in chlorhexidine gluconate, chlorhexidine acetate, poly hexamethylene biguanide, Benzalkonii Chloridum, benzalkonium bromide and benzethonium chloride.
4. a kind of quick-dry type hand disinfection emulsion according to claim 1, is characterized in that described emulsifing thickener is one or more in polyacrylamide, sodium polyacrylate, isoparaffin, fatty alcohol-polyoxyethylene ether, fatty acid ester and fatty alcohol.
5. a kind of quick-dry type hand disinfection emulsion according to claim 1, it is characterized in that described emollient be natural minerals oils and fats, animal oil, Vegetable oil lipoprotein, synthetic ester oil, polyhydric alcohol one or more.
6. a kind of quick-dry type hand disinfection emulsion according to claim 2, is characterized in that described short chain alcohol is ethanol.
7. a kind of quick-dry type hand disinfection emulsion according to claim 3, is characterized in that described cationic germicide is one or both in chlorhexidine gluconate, benzethonium chloride, and is medical rank raw material.
8. a kind of quick-dry type hand disinfection emulsion according to claim 7, is characterized in that described cationic germicide is chlorhexidine gluconate.
9. a kind of quick-dry type hand disinfection emulsion according to claim 4, is characterized in that described emulsifing thickener is one or more in polyacrylamide, isoparaffin, fatty alcohol-polyoxyethylene ether, fatty alcohol.
10. a kind of quick-dry type hand disinfection emulsion according to claim 9, is characterized in that described isoparaffin carbon number is 10 to 30.
11. a kind of quick-dry type hand disinfection emulsion according to claim 10, is characterized in that described isoparaffin carbon number is 10 to 22.
12. a kind of quick-dry type hand disinfection emulsion according to claim 9, it is characterized in that described fatty alcohol-polyoxyethylene ether carbon number is 10 to 30, ethylene oxide number is 1-50.
13. a kind of quick-dry type hand disinfection emulsion according to claim 12, it is characterized in that described fatty alcohol-polyoxyethylene ether carbon number is 10 to 20, ethylene oxide number is 1-30.
14. a kind of quick-dry type hand disinfection emulsion according to claim 9, is characterized in that described fatty alcohol carbon number is 6 to 30.
15. a kind of quick-dry type hand disinfection emulsion according to claim 14, is characterized in that described fatty alcohol carbon number is preferably 10 to 25.
16. a kind of quick-dry type hand disinfection emulsion according to claim 5, is characterized in that described emollient is one or more in vaseline, white oil, Jojoba oil, lanoline, squalane, glycerol.
17. a kind of quick-dry type hand disinfection emulsion according to claim 1, is characterized in that its viscosity at 25 DEG C is 3000cP to 30000cP, and prepare at normal temperatures.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510951822.2A CN105362103A (en) | 2015-12-19 | 2015-12-19 | Quick-drying hand disinfection emulsion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510951822.2A CN105362103A (en) | 2015-12-19 | 2015-12-19 | Quick-drying hand disinfection emulsion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105362103A true CN105362103A (en) | 2016-03-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510951822.2A Pending CN105362103A (en) | 2015-12-19 | 2015-12-19 | Quick-drying hand disinfection emulsion |
Country Status (1)
| Country | Link |
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| CN (1) | CN105362103A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105919986A (en) * | 2016-05-20 | 2016-09-07 | 蔡华英 | Fungicide |
| CN108379116A (en) * | 2018-04-11 | 2018-08-10 | 南京巨鲨显示科技有限公司 | A kind of liposomal rapid-curing cutback hand-wrist bones lotion |
| EP3471696A4 (en) * | 2016-06-20 | 2020-03-11 | Essity Hygiene And Health Aktiebolag | Hand sanitizing composition |
| CN111135302A (en) * | 2020-01-17 | 2020-05-12 | 稳领(天津)医学科技有限公司 | Hand-washing-free disinfection gel and preparation method thereof |
| WO2020117238A1 (en) * | 2018-12-06 | 2020-06-11 | Colgate-Palmolive Company | Personal care compositions |
| CN112890661A (en) * | 2021-03-17 | 2021-06-04 | 康春雨 | Quick-drying wet tissue special for screen door frame and using method thereof |
| FR3111073A1 (en) * | 2020-06-08 | 2021-12-10 | Naos Institute Of Life Science | ECOBIOLOGICAL LIPOALCOOLIC COMPOSITION |
| WO2022050680A1 (en) * | 2020-09-07 | 2022-03-10 | ㈜아모레퍼시픽 | Sanitizer composition in emulsion formulation |
| CN117430825A (en) * | 2023-12-20 | 2024-01-23 | 广东迪美生物技术有限公司 | Graphene oxide/polyurethane biguanide composite material and preparation method and antibacterial application thereof |
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| CN101548983A (en) * | 2009-04-25 | 2009-10-07 | 广西佳华医疗卫生用品有限公司 | Skin disinfectant and method of producing the same |
| CN101959509A (en) * | 2008-03-07 | 2011-01-26 | 金伯利-克拉克环球有限公司 | Alcohol antimicrobial skin sanitizing compositions including cationic compatible thickeners |
| CN102246794A (en) * | 2011-06-08 | 2011-11-23 | 江中药业股份有限公司 | Composition for killing microbes |
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2015
- 2015-12-19 CN CN201510951822.2A patent/CN105362103A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101959509A (en) * | 2008-03-07 | 2011-01-26 | 金伯利-克拉克环球有限公司 | Alcohol antimicrobial skin sanitizing compositions including cationic compatible thickeners |
| CN101548983A (en) * | 2009-04-25 | 2009-10-07 | 广西佳华医疗卫生用品有限公司 | Skin disinfectant and method of producing the same |
| CN102246794A (en) * | 2011-06-08 | 2011-11-23 | 江中药业股份有限公司 | Composition for killing microbes |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105919986A (en) * | 2016-05-20 | 2016-09-07 | 蔡华英 | Fungicide |
| EP3471696A4 (en) * | 2016-06-20 | 2020-03-11 | Essity Hygiene And Health Aktiebolag | Hand sanitizing composition |
| CN108379116A (en) * | 2018-04-11 | 2018-08-10 | 南京巨鲨显示科技有限公司 | A kind of liposomal rapid-curing cutback hand-wrist bones lotion |
| AU2018451738B2 (en) * | 2018-12-06 | 2022-08-04 | Colgate-Palmolive Company | Personal care compositions |
| WO2020117238A1 (en) * | 2018-12-06 | 2020-06-11 | Colgate-Palmolive Company | Personal care compositions |
| US12083212B2 (en) | 2018-12-06 | 2024-09-10 | Colgate-Palmolive Company | Personal care compositions |
| CN113164361A (en) * | 2018-12-06 | 2021-07-23 | 高露洁-棕榄公司 | Personal care compositions |
| CN113164361B (en) * | 2018-12-06 | 2024-04-02 | 高露洁-棕榄公司 | Personal care compositions |
| CN111135302A (en) * | 2020-01-17 | 2020-05-12 | 稳领(天津)医学科技有限公司 | Hand-washing-free disinfection gel and preparation method thereof |
| WO2021249661A1 (en) * | 2020-06-08 | 2021-12-16 | Naos Institute Of Life Science | Ecobiological lipo-alcoholic composition |
| FR3111073A1 (en) * | 2020-06-08 | 2021-12-10 | Naos Institute Of Life Science | ECOBIOLOGICAL LIPOALCOOLIC COMPOSITION |
| WO2022050680A1 (en) * | 2020-09-07 | 2022-03-10 | ㈜아모레퍼시픽 | Sanitizer composition in emulsion formulation |
| CN112890661A (en) * | 2021-03-17 | 2021-06-04 | 康春雨 | Quick-drying wet tissue special for screen door frame and using method thereof |
| CN117430825A (en) * | 2023-12-20 | 2024-01-23 | 广东迪美生物技术有限公司 | Graphene oxide/polyurethane biguanide composite material and preparation method and antibacterial application thereof |
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Application publication date: 20160302 |