CN105169457B

CN105169457B - A kind of cation medical dressing and preparation method thereof

Info

Publication number: CN105169457B
Application number: CN201510529263.6A
Authority: CN
Inventors: 梁奕福
Original assignee: Guangxi Daqing Biotechnology Co Ltd; GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co Ltd; Dongguan Da Qing Medical Devices Co Ltd
Current assignee: Guangxi Daqing Biotechnology Co Ltd; GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co Ltd; Dongguan Da Qing Medical Devices Co Ltd
Priority date: 2015-08-26
Filing date: 2015-08-26
Publication date: 2018-03-23
Anticipated expiration: 2035-08-26
Also published as: CN105169457A

Abstract

The present invention relates to a kind of cation medical dressing and preparation method thereof.Cation medical dressing is by following raw material（Weight ratio）Composition：Chitosan quaternary ammonium salt 1.2% ~ 2%, polyhexamethylene guanide 0.2% ~ 0.35%, L-Ascorbic Acid L-O-Phosphate 0.2% ~ 0.7%, Porcine HGF 0.005% ~ 0.015%, ceramide 0.2% ~ 0.5%, allantoin 0.15% ~ 0.25%, camellia oil 0.08% ~ 0.16%, glycerine 6% ~ 10%, peppermint oil 0.5% ~ 0.7%, purifying water surplus.Compromised skin can be carried out quickly to repair by the present invention and sterilization processing, and does not leave scar.Can isolate and kill bacterium, fungi, virus, prevent skin and mucosa infection, have stop blooding and keep the surface of a wound moistening, moreover it is possible to promote surface of a wound skin repair heal.It can be widely used for the prevention and treatment of the local mucosa infections such as skin wound infection and oral cavity, throat, gum.

Description

A kind of cation medical dressing and preparation method thereof

Technical field

The present invention relates to technique in skin care field, more particularly to a kind of cation medical dressing and preparation method thereof.

Background technology

In the developmental process of people, injured unavoidably by the external world, such as scratch, burn and scald, bedsore, hemorrhoid, skin by To after severe trauma, its wound site is subject to the infection of bacterium, fungi and virus, it is necessary to which the long period is extensive after infection It is multiple, while scar may be left.

The content of the invention

It is an object of the invention to solve the deficiencies in the prior art, there is provided a kind of cation medical dressing and its preparation side Method, wound site can be nursed, the isolation to bacterium, fungi, virus；So that wound site Fast Restoration；And it can keep away Exempt to leave scar.

To reach above-mentioned purpose, the technical solution adopted by the present invention is：

A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.2% ~ 2%

Polyhexamethylene guanide 0.2% ~ 0.35%

L-Ascorbic Acid L-O-Phosphate 0.2% ~ 0.7%

Porcine HGF 0.005% ~ 0.015%

Ceramide 0.2% ~ 0.5%

Allantoin 0.15% ~ 0.25%

Camellia oil 0.08% ~ 0.16%

Glycerine 6% ~ 10%

Peppermint oil 0.5% ~ 0.7%

Purify water surplus.

Water speed dissolved cation chitosan quaternary ammonium salt has good antibiotic property, film forming, Cation adsorption, moisture-absorbing moisture-keeping The performance such as property, flocculability, antistatic behaviour.Its anti-microbial property is better than chitosan and other chitosan derivatives.Chitosan quaternary ammonium salt After being dissolved in water, ionize, substantial amounts of level Four ammonium cation is contained in solution.Ammonium cation has one to bacterium, fungi, virus Determine fragmentation effect.

Secondly polyhexamethylene guanide, has broad-spectrum；Valid density is low；Work fast；Property is stable；It is soluble in water Premium properties；It can use at normal temperatures；It is long-term it is antibacterial, have no side effect；Polyhexamethylene guanide is polyguanidine family macromolecule polymer, Ionization can be produced in aqueous, and its hydrophilic base section contains strong electropositive, and absorption is generally in electronegative all kinds of thin Bacterium, virus, into cell membrane, suppress the synthesis of film lactones plastid, cause thalline apoptosis, reach optimal bactericidal effect.

Chitosan quaternary ammonium salt, polyhexamethylene guanide are produced and form cation, and bacterium, fungi and virus can be carried out Kill and isolate.

L-Ascorbic Acid L-O-Phosphate is vitamin C derivatives, be using vitamin C as raw material modern science and technology processing and It is no matter oral or after being absorbed into human body by skin into, this product, it can digest dimension of dissociating rapidly by phosphate and give birth to Plain C, play the distinctive biochemical functions of vitamin C.

L-Ascorbic Acid L-O-Phosphate is a kind of water-soluble whitening agent.This product can be reasonably resistant to ultraviolet after skin absorbs Invasion and attack, and oxygen radical can be captured, promote collagen generation, can effectively prevent and treat pigmentation, dispel various skin splash, energy Make skin moisturizing, delicate, bright and clean and this product stable, it is nontoxic, non-stimulated, it is the excellent addition of modern functional skin-lightening cosmetic Agent, also have：1st, tyrosinase activity processed, melanin, tool freckle removing and whitening effect are reduced.2nd, into vivo after can eliminate oxygen freedom Base, wrinkle, anti-senescence function are removed so as to have.3rd, there is synergy with vitamin E.

Porcine HGF is a kind of multifunctional powerful cell factor, to promoting fibroblastic metabolism and collagen Formation play critical function.Porcine HGF can promote the growth and breeding of skin histology, and it passes through special with cell surface Isoreceptor combines, and regulates and controls skin epidermis, division, breeding and the Growth and Differentiation of endothelium and stroma cell, promotes cell metabolism, enhancing Oxidation；Relevant with skin injury cell can be promoted mushrooms out breeding, and adjust the synthesis of intercellular matrix, secrete and Decompose；The regeneration of corneocyte can be promoted, accelerate the reparation of keratoderma and hypothallus, promote the life of human skin cell It is long；Synthesis and the cell metabolism of the protein of Skin Cell can be strengthened, there is delaying skin cell ageing, promote epidermal cell Reparation and growth, make skin smooth plump.

Glycerine, i.e. glycerine is colourless sweet clear and bright thick liquid, odorless；There is warm sweet taste.Glycerine can be with draw air Moisture content to skin moisture-keeping, the moisture content in skin can also be pinned, not allow it to be lost in.The effect of with moisturizing.To the skin of baby Skin can play moisturizing, moist effect.

Peppermint oil, the skin of unclean obstruction can be nursed one's health, its refrigerant sensation, capilary can be shunk, releived and itched, send out It is scorching and burn, also can soft skin, for removing blackhead and oily skin also great effect.

Peppermint oil has inhibitory action to herpes simplex virus, forest virus, mumps virus, to golden yellow Portugal Grape coccus, staphylococcus albus, alpha streptococcus, beta streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax Bacillus, corynebacterium diphtheriae, typhoid bacillus, Pseudomonas aeruginosa, Escherichia coli etc. have bacteriostasis；Water-soluble peppermint oil can stimulate neural end The cold receptor of the tip and produce creeping chill, and reflectivity cause the change of deep tissue blood vessel and play anti-inflammatory, analgesic, antipruritic Effect.

Ceramide is also known as sphingolipid, is a kind of lipid for being present in skin, in epidermal keratinocytes layer formation process Play an important role.When drying, furfur, cracking phenomena occurs in skin, when its barrier function substantially reduces, skin supplement is neural Acid amides can recover moisturizing and barrier function rapidly.

Cause dry skin main cause be in horny layer of epidermis ceramide content reduce, ceramide content height with Skin dryness is directly related.Adhesion strength between keratinocyte can be remarkably reinforced using ceramide, improves dry skin journey Degree, reduce desquamation of skin phenomenon.Ceramide has hydrone ability of associating by force very much, and it in cuticula by forming netted knot Structure maintains moisture of skin.Therefore, ceramide, which has, keeps moisture of skin effect.It can be made using ceramide in horny layer of epidermis Ceramide content increases, and can improve the situation such as dry skin, furfur, coarse；Ceramide can increase horny layer of epidermis simultaneously Thickness, skin moisture holding capacity is improved, reduce wrinkle, strengthen skin elasticity, delay skin aging.

Ceramide is a kind of water-soluble lipid matter, and it is close with the structure of matter for forming keratoderma, can be quickly The water penetrated into skin, and cuticula combines, and forms a kind of network structure, pins moisture.

Allantoin：Alias Allantoin, Allantoin, Allantion, Allantoin, it is a kind of second Interior ureide derivative.A kind of nontoxic, tasteless and nonirritant, without hypersensitive white crystal, in water crystallization for single prism or Colorless crystalline powder.Hot water, hot alcohol and diluted sodium hydroxide solution can be dissolved in.The water and alcohol of normal temperature are slightly soluble in, is insoluble in ether With the organic solvent such as chloroform；Its saturated aqueous solution (concentration 0.6%) is in subacidity；PH is 5.5.In the water that pH value is 4-9 It is stable in solution.Also stablize in nonaqueous solvents and dry air；Decomposable asymmetric choice net under boiling and be exposed to sunlight in strong alkali solution. Weakly acidic condition is improved for Porcine HGF.

Allantoin, which has, promotes cell growth, accelerates the physiological function such as wound healing, cutin-softening albumen, is skin trauma Good consolidant and antiulcer agents.It can be used as alleviating and treat xerodermia, scaling skin illness, skin ulcer, disappear Change road ulcer and inflammation, have good therapeutic effect to osteomyelitis, diabetes, hepatic sclerosis, acne.

Because allantoin is a kind of amphoteric compound, can combine many kinds of substance formed double salt, have lucifuge, sterilization and anticorrosion, Analgesic, antioxidation, skin can be made to keep moisture content, moistened and soft, be the additive of the cosmetics such as cosmetology, extensively General adding for freckle cream, anti-acne toner, shampoo, perfumed soap, toothpaste, shaving lotion, conditioner, astringent, anti-sweat deodorization lotion etc. Add agent.The cosmetics of addition allantoin have protective tissue, it is hydrophilic, absorb water and prevent moisture from the effect such as distributing；Add allantoin Hair-cream, hair cream, shampoo, have protective effect to hair, can make hair not bifurcated, constantly hair；Add lipstick, the face of allantoin Skin, lip can be made soft for frost and high resilience, and has the gloss of beauty.Allantoin promotion organization grows, cell metabolism, Cutin-softening layer albumen.

Camellia oil is nutritious, fatty acids（Unrighted acid 93%, wherein oleic acid 82%, linoleic acid 11%）, camellia Glucoside, Tea Polyphenols, saponin, tannin, and the squalene rich in antioxidant and with anti-inflammatory effect, squalene and Flavonoid substances, Play the role of to anticancer splendid.Camellia oil is also rich in the trace element such as vitamin E and calcium, iron, zinc, by physician and nutrition Family is described as the Zn-ef ficiency of " flowers of life ", and content is 10 times of soybean oil, therefore camellia oil containing substantial amounts of aliphatic acid due to having There is good lubricant effect.

After skin is by wound, easy breed bacteria of site of injury etc., chitosan quaternary ammonium salt, polyhexamethylene guanide produce big Cation is measured, can be used for sterilizing；Tissue is avoided to produce substantial amounts of leucocyte formation scar so that the surface of a wound is not infected；Together When peppermint oil assisting sterilisation.Glycerine, camellia oil play lubrication, the effect of skin care, coordinate with ceramide, keep skin Moisture, avoid dry, pigementation；Secondly camellia oil also acts as anti-inflammatory, and its active ingredient squalene can promote collagen Generation, promote new skin histology to grow；Ceramide can also play anti-allergic effects.Allantoin is matched somebody with somebody with Porcine HGF Close, promote dermal cell growth, repair the cell by wound, promote wound healing；Allantoin also acts as cutin-softening layer albumen, The effect of dead skin is removed, prevents dead skin from hindering new skin histology growth.L-Ascorbic Acid L-O-Phosphate can capture oxygen radical, promote Collagen generates, and can effectively prevent and treat pigmentation, dispel various skin splash, can make skin moisturizing；Primarily serve anti-oxidant And whitening effect.

Preferably, the content summation of chitosan quaternary ammonium salt and polyhexamethylene guanide is no more than 2.3%.Two kinds of compositions are killing While bacterium, the leucocyte in Skin Cell and skin histology may be hurt；By clinical trial analysis, when its weight surpasses A timing is crossed, influences whether that leucocyte works.

Preferably, a kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.3% ~ 1.8%

Polyhexamethylene guanide 0.3% ~ 0.32%

L-Ascorbic Acid L-O-Phosphate 0.3% ~ 0.6%

Porcine HGF 0.008% ~ 0.012%

Ceramide 0.2% ~ 0.4%

Allantoin 0.17% ~ 0.23%

Camellia oil 0.08% ~ 0.12%

Glycerine 7% ~ 9%

Peppermint oil 0.5% ~ 0.7%

Purify water surplus.

More preferably, a kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.5%

Polyhexamethylene guanide 0.3%

L-Ascorbic Acid L-O-Phosphate 0.5%

Porcine HGF 0.01%

Ceramide 0.3%

Allantoin 0.2%

Camellia oil 0.1%

Glycerine 8%

Peppermint oil 0.6%

Purify water surplus.

A kind of preparation method of above-mentioned cation medical dressing, including：

Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, L-Ascorbic Acid L-O-Phosphate, neural acyl Amine, Porcine HGF, allantoin, camellia oil, glycerine, peppermint oil；

Step 2: weigh the purified water of formula ratio；

Step 3, the formula of step 1 is poured into purified water successively and mixed.

Chitosan quaternary ammonium salt 1.3% ~ 1.8%

Polyhexamethylene guanide 0.3% ~ 0.32%

L-Ascorbic Acid L-O-Phosphate 0.3% ~ 0.6%

Porcine HGF 0.008% ~ 0.012%

Ceramide 0.2% ~ 0.4%

Allantoin 0.17% ~ 0.23%

Camellia oil 0.08% ~ 0.12%

Glycerine 7% ~ 9%

Peppermint oil 0.5% ~ 0.7%

Aloin 0.8% ~ 1%

Purify water surplus.

Aloin can help to discharge internal dirt, purification blood, softening blood vessel, reduce blood pressure and blood viscosity, promote blood Liquid circulates；Mixture of the active component based on barbaloin, it is dicotyledon aloe extract.Bactericidal action, antiinflammatory action, Beautification function is moistened, the effect of letting out under stomach invigorating, cardiac stimulant promoting blood circulation effect, is immunized and palingenesis, immune and antitumor action, removing toxic substances are made With, anti-aging effects, analgesia, sedation, anti-sunlight function.The polysaccharide and multivitamin contained in aloe has good to human body skin Nutrition well, moisten, whitening effect.Aloe barbadensis Miller is the Fresh leaf of aloe of the direct beauty of optimum, i.e. aloe barbadensis Miller, and it has Make skin contraction, softness, moisturizing, anti-inflammatory, the performance of bleaching.Hardening, angling, the effect for improving scar are also released, not only Small wrinkle, pouch, cutis laxa can be prevented, moreover it is possible to skin wet, tender and lovely is kept, at the same time it can also treat scytitis, to powder Thorn, freckle, acne and scald, knife wound, insect bite etc. also have the effect of fine.It is similarly effective to hair, hair can be kept Moisten smooth, pre-Anti-hair loss.

When skin is by wound, sometimes along with bleeding；Especially scald, can also be along with inflammation；Increase in dressing Add a certain amount of aloin, certain haemostatic effect and antibacterial, anti-inflammatory can be played；By clinical test, not with other drugs Composition conflict.

Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, L-Ascorbic Acid L-O-Phosphate, neural acyl Amine, Porcine HGF, allantoin, camellia oil, glycerine, peppermint oil, aloin；

Step 2: weigh the purified water of formula ratio；

It is further preferred that a kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.3% ~ 1.8%

Polyhexamethylene guanide 0.3% ~ 0.32%

L-Ascorbic Acid L-O-Phosphate 0.3% ~ 0.6%

Porcine HGF 0.008% ~ 0.012%

Ceramide 0.2% ~ 0.4%

Allantoin 0.17% ~ 0.23%

Camellia oil 0.08% ~ 0.12%

Glycerine 7% ~ 9%

Peppermint oil 0.5% ~ 0.7%

Aloin 0.8% ~ 1%

Hydrogen peroxide 1% ~ 2%

Purify water surplus.

Hydrogen peroxide has preferable oxidation effectiveness, using low concentration（Especially weight ratio is less than 3%）Hydrogen peroxide and skin Wound, fester or dirt when meeting, decompose generation oxygen immediately.This oxygen atom for being not yet combined into oxygen molecule, have very strong Oxidability, when being contacted with bacterium, microorganism can be destroyed, kill bacterium.An aerobic environment can be provided simultaneously, is killed The collagen of anaerobic bacteria and aid in skin is formed.Here the content of hydrogen peroxide refers to：Weight of the hydrogen peroxide in whole dressing Measure content：1%~2%.

Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, L-Ascorbic Acid L-O-Phosphate, neural acyl Amine, Porcine HGF, allantoin, camellia oil, glycerine, peppermint oil, aloin, hydrogen peroxide；

Step 2: weigh the purified water of formula ratio；

Because the hydrogen peroxide of content 100% is difficult to obtain, the hydrogen peroxide for the quality such as the hydrogen peroxide in step 1 uses, other are dense Hydrogen peroxide is spent to substitute；That is step 1, when with hydrogen peroxide is taken, it can match somebody with somebody and take other concentration hydrogen peroxide of equivalent, such as match somebody with somebody to take and contain Measure 30% hydrogen peroxide of hydrogen peroxide（Quality containing hydrogen peroxide is equal）；Step 2 replaces with：Weigh the purified water of surplus.

Beneficial effects of the present invention are：

1）, using chitosan quaternary ammonium salt, polyhexamethylene guanide etc. have bactericidal effect to skin trauma position, avoid feeling again Dye；

2）, skin trauma position can be maintained using glycerine, camellia oil etc., avoid skin from losing water from wound site Point.

3）, secondly, using repair composition, skin is repaired, avoids the occurrence of scar.

Fast skin reparation is can reach, and does not leave scar.

Embodiment

The present invention is described further below.

Embodiment 1：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.2%

Polyhexamethylene guanide 0.35%

L-Ascorbic Acid L-O-Phosphate 0.2%

Porcine HGF 0.015%

Ceramide 0.5%

Allantoin 0.15%

Camellia oil 0.08%

Glycerine 10%

Peppermint oil 0.5%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 1：

Huang, man, 11 years old, arm was scalding, and wound has a suppuration, after wound cleaning, smear the sun of the present embodiment from Sub- medical dressing one month, 3 times a day；Wound healing, and substantially without scar.

Embodiment 2：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 2%

Polyhexamethylene guanide 0.2%

L-Ascorbic Acid L-O-Phosphate 0.7%

Porcine HGF 0.005%

Ceramide 0.2%

Allantoin 0.25%

Camellia oil 0.16%

Glycerine 10%

Peppermint oil 0.6%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 2

Zhang, female, 10 years old, arm was scalded by oil；Arm is got blister；After treatment of wounds, the cation of the present embodiment is applied Medical dressing 3 weeks, 3 times a day, wound take a turn for the better；New skin tissue growth, and scar is very light；Persistently use 2 weeks again, wound healing, Without scar.

Embodiment 3：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.3%

Polyhexamethylene guanide 0.32%

L-Ascorbic Acid L-O-Phosphate 0.6%

Porcine HGF 0.012%

Ceramide 0.4%

Allantoin 0.17%

Camellia oil 0.12%

Glycerine 7%

Peppermint oil 0.5%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 3

Lin, man, 10 years old, with it after injury, there is pigementation in injury ulcer, trauma skin periphery；Apply this reality Apply the cation medical dressing of example one week, at least 3 times daily, start to cut down at ulcer；Persistently use 3 weeks, pigment disappears, wound Healing.

Embodiment 4：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.5%

Polyhexamethylene guanide 0.3%

L-Ascorbic Acid L-O-Phosphate 0.5%

Porcine HGF 0.01%

Ceramide 0.3%

Allantoin 0.2%

Camellia oil 0.1%

Glycerine 8%

Peppermint oil 0.6%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 4：

Lee, man, 15 years old, arm scratch is fallen down in running；Skin begins with ulcer sign and with inflammation；To wound portion After cleaning, the cation medical dressing of film the present embodiment one week, 3 times a day, inflammation starts to cut down, new skin tissue growth；4 weeks After cure.

Embodiment 5：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.3%

Polyhexamethylene guanide 0.32%

L-Ascorbic Acid L-O-Phosphate 0.6%

Porcine HGF 0.008%

Ceramide 0.4%

Allantoin 0.17%

Camellia oil 0.12%

Glycerine 9%

Peppermint oil 0.5%

Aloin 0.8%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 5

Zhang, man, 15 years old, with hemorrhoid；Skin is scratched, itch, and has pigment to start to precipitate；Use the present embodiment After cation medical dressing one week, coating at least 3 times daily, itch gradually disappears or weakened, pigment removal；After 4 weeks, scabies is opened Begin healing and the non-pigment precipitation of scabbing.

Embodiment 6：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.8%

Polyhexamethylene guanide 0.3%

L-Ascorbic Acid L-O-Phosphate 0.3%

Porcine HGF 0.012%

Ceramide 0.2%

Allantoin 0.17%

Camellia oil 0.08%

Glycerine 7%

Peppermint oil 0.7%

Aloin 1%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 6

Lin, man, 32 years old, with skin eczema；Skin is scratched, itch, and has inflammation；Using the present embodiment sun from Sub- medical dressing is after one week, and at least 3 times daily, itch gradually disappears or weakened, inflammation slows down；After 4 weeks, start the healing that scabs.

Embodiment 7：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.6%

Polyhexamethylene guanide 0.31%

L-Ascorbic Acid L-O-Phosphate 0.4%

Porcine HGF 0.01%

Ceramide 0.3%

Allantoin 0.2%

Camellia oil 0.1%

Glycerine 8%

Peppermint oil 0.6%

Aloin 0.9%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 7

Field, female, 41 years old, with eczema；Skin is scratched, itch, and red point occurs；Use the cation of the present embodiment After medical dressing one hour, itch gradually disappears or weakened；After 6 hours, red point disappears.

Embodiment 8：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.3%

Polyhexamethylene guanide 0.3%

L-Ascorbic Acid L-O-Phosphate 0.6%

Porcine HGF 0.012%

Ceramide 0.2%

Allantoin 0.17%

Camellia oil 0.08%

Glycerine 9%

Peppermint oil 0.7%

Aloin 1%

Hydrogen peroxide 2%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 8：Zhang, female, 32 years old, it is burned, epidermis has ulcer, bubble；After wound cleaning, the sun of the present embodiment is smeared Ion medical dressing, wound scab, and daily after at least 3 times, one week, wound starts to heal, and new skin tissue growth, wound perimeter goes out Existing pigementation；After 4 weeks, wound healing；Pigment disappears；Without scar.

Embodiment 9：

Chitosan quaternary ammonium salt 1.8%

Polyhexamethylene guanide 0.32%

L-Ascorbic Acid L-O-Phosphate 0.3%

Porcine HGF 0.008%

Ceramide 0.4%

Allantoin 0.23%

Camellia oil 0.12%

Glycerine 7%

Peppermint oil 0.5%

Aloin 0.8%

Hydrogen peroxide 1%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 9：Certain is closed, female, 63 years old, skin is fallen down and is scratched, and part wound is deeper；After wound cleaning, this reality is applied The cation medical dressing of example is applied, at least 3 times daily, wound starts to scab, and is healed after one week；Without Infective morbidity；And without scar Trace.

Embodiment 10：A kind of cation medical dressing, by following raw material（Weight ratio）Composition：

Chitosan quaternary ammonium salt 1.5%

Polyhexamethylene guanide 0.3%

L-Ascorbic Acid L-O-Phosphate 0.5%

Porcine HGF 0.01%

Ceramide 0.3%

Allantoin 0.2%

Camellia oil 0.1%

Glycerine 8%

Peppermint oil 0.6%

Aloin 1%

Hydrogen peroxide 2%

Purify water surplus.

Step 2: weigh the purified water of formula ratio；

Case 10：Zhang, man, 41 years old, with bleb；Part has ulcer；The cation medical dressing of the present embodiment is applied, After daily at least 3 times, continuous 5 days, ulcer wound starts to scab, and bleb starts to eliminate after 3 weeks；And without scar.

It the above is only the preferred embodiment of the application, equivalent technical solutions on this basis still fall within application protection model Enclose.

Claims

A kind of 1. cation medical dressing, it is characterised in that：Comprise the following raw materials by weight percent：

Chitosan quaternary ammonium salt 1.2%~2%

Polyhexamethylene guanide 0.2%~0.35%

L-Ascorbic Acid L-O-Phosphate 0.2%~0.7%

Porcine HGF 0.005%~0.015%

Ceramide 0.2%~0.5%

Allantoin 0.15%~0.25%

Camellia oil 0.08%~0.16%

Glycerine 6%~10%

Peppermint oil 0.5%~0.7%

Purify water surplus.
A kind of 2. cation medical dressing according to claim 1, it is characterised in that：By the raw material of following percentage by weight Composition：

Chitosan quaternary ammonium salt 1.3%~1.8%

Polyhexamethylene guanide 0.3%~0.32%

L-Ascorbic Acid L-O-Phosphate 0.3%~0.6%

Porcine HGF 0.008%~0.012%

Ceramide 0.2%~0.4%

Allantoin 0.17%~0.23%

Camellia oil 0.08%~0.12%

Glycerine 7%~9%

Peppermint oil 0.5%~0.7%

Purify water surplus.
A kind of 3. cation medical dressing according to claim 1, it is characterised in that：By the raw material of following percentage by weight Composition：

Chitosan quaternary ammonium salt 1.5%

Polyhexamethylene guanide 0.3%

L-Ascorbic Acid L-O-Phosphate 0.5%

Porcine HGF 0.01%

Ceramide 0.3%

Allantoin 0.2%

Camellia oil 0.1%

Glycerine 8%

Peppermint oil 0.6%

Purify water surplus.
A kind of 4. cation medical dressing, it is characterised in that：Comprise the following raw materials by weight percent：

Chitosan quaternary ammonium salt 1.3%~1.8%

Polyhexamethylene guanide 0.3%~0.32%

L-Ascorbic Acid L-O-Phosphate 0.3%~0.6%

Porcine HGF 0.008%~0.012%

Ceramide 0.2%~0.4%

Allantoin 0.17%~0.23%

Camellia oil 0.08%~0.12%

Glycerine 7%~9%

Peppermint oil 0.5%~0.7%

Aloin 0.8%~1%

Purify water surplus.
A kind of 5. cation medical dressing, it is characterised in that：Comprise the following raw materials by weight percent：

Chitosan quaternary ammonium salt 1.3%~1.8%

Polyhexamethylene guanide 0.3%~0.32%

L-Ascorbic Acid L-O-Phosphate 0.3%~0.6%

Porcine HGF 0.008%~0.012%

Ceramide 0.2%~0.4%

Allantoin 0.17%~0.23%

Camellia oil 0.08%~0.12%

Glycerine 7%~9%

Peppermint oil 0.5%~0.7%

Aloin 0.8%~1%

Hydrogen peroxide 1%~2%

Purify water surplus.
6. a kind of preparation method of any described cation medical dressing of claims 1 to 3, including：

Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, L-Ascorbic Acid L-O-Phosphate, ceramide, thin The intracellular growth factor, allantoin, camellia oil, glycerine, peppermint oil；

Step 2: weigh the purified water of formula ratio；

Step 3, the formula of step 1 is poured into purified water successively and mixed.
7. a kind of preparation method of the cation medical dressing described in claim 4, including：

Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, L-Ascorbic Acid L-O-Phosphate, ceramide, thin The intracellular growth factor, allantoin, camellia oil, glycerine, peppermint oil, aloin；

Step 2: weigh the purified water of formula ratio；

Step 3, the formula of step 1 is poured into purified water successively and mixed.
8. a kind of preparation method of the cation medical dressing described in claim 5, including：

Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, L-Ascorbic Acid L-O-Phosphate, ceramide, thin The intracellular growth factor, allantoin, camellia oil, glycerine, peppermint oil, aloin, hydrogen peroxide；

Step 2: weigh the purified water of formula ratio；

Step 3, the formula of step 1 is poured into purified water successively and mixed.