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CN104998307B - Three layers of PVC soft shell filters of side opening - Google Patents

Three layers of PVC soft shell filters of side opening Download PDF

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Publication number
CN104998307B
CN104998307B CN201510389005.2A CN201510389005A CN104998307B CN 104998307 B CN104998307 B CN 104998307B CN 201510389005 A CN201510389005 A CN 201510389005A CN 104998307 B CN104998307 B CN 104998307B
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CN
China
Prior art keywords
filter
caudacoria
membranous layer
cephacoria
heat seal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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CN201510389005.2A
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Chinese (zh)
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CN104998307A (en
Inventor
钦湘
孙号
谢伟娟
肖国锋
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NANJING SHUANGWEI BIOTECHNOLOGY CO Ltd
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NANJING SHUANGWEI BIOTECHNOLOGY CO Ltd
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Priority to CN201510389005.2A priority Critical patent/CN104998307B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0281Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • A61M1/0218Multiple bag systems for separating or storing blood components with filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/029Separating blood components present in distinct layers in a container, not otherwise provided for

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a kind of three layers of PVC soft shell filters of side opening, including inlet tube, cephacoria, filter membranous layer, the first caudacoria, the second caudacoria and outlet;Cephacoria heat seal connection filter membranous layer periphery, filtering ante-chamber is formed with the front side of filter membranous layer, the remainder of cephacoria is connected on front side of filter membranous layer heat seal portion on front side of outlet, second caudacoria is connected on front side of outlet from filter membranous layer heat seal portion, makes to form filtering back cavity between the first caudacoria, the second caudacoria and filter membranous layer.The present invention reduces the surface area of filter ante-chamber in the case where filter area is constant, and the surface area for filtering ante-chamber is equal to filter area, blood is set by filter membrane, to reduce blood loss completely, further reduce the extruding to port of export conduit, make filtering more unobstructed, will not blockage phenomenon;The present invention only with three layers of PVC film, cost of implementation it is effectively save.

Description

Three layers of PVC soft shell filters of side opening
Technical field
The present invention relates to medicine and hygiene fields, relate in particular to a kind of three layers of PVC soft shell leukocyte depletion filters of side opening.
Background technology
The research of modern transfusion science shows, non-therapeutic component leucocyte is a kind of " polluter " in blood, allogeneic Leukocyte antibody can be produced after blood transfusion, causes a series of adverse reaction and side effect.Clinical data shows a certain proportion of defeated Blood person has different degrees of transfusion reaction, such as:Nonhemolytic febrific reaction, Inefficacy of Platelets Transfusion, transfusion-associated graft Anti- host disease(GVHD), cytomegalovirus(CMV)Infection etc..Therefore, blood and its component remove leucocyte to transfusion safety and Clinical treatment is of great significance.
As shown in Figure of description Fig. 1, original soft shell filter includes outer membrane 1 ' and outer membrane 2 ' and filter membrane component after filter before filter, The filter membrane component is located at before filter after outer membrane 1 ' and filter between outer membrane 2 ', so as to form before filter sap cavity 20 ' after sap cavity 10 ' and filter, is filtered Membrane module includes filter membranous layer 3 ' and the two panels PVC inner membrances ring 4 ' for being respectively provided at filter membranous layer both sides, the inner edge of the PVC inner membrances ring 4 ' Edge is connected with the outer fringe seal of filter membranous layer 3 ', at the same before the outer rim of inner membrance ring 4 ' and filter outer membrane 1 ' and filter after outer membrane 2 ' outer rim it is close Envelope connection.Sap cavity before the connection filter of inlet tube 11 ', sap cavity after the connection filter of outlet 21 ', and it is parallel with filter membranous layer 3 '.
The soft shell filter of the technology needs to spend four tunics, and wherein two panels inner membrance ring will cut off bulk center section, from material Significant wastage is caused in material cost.In addition, being filtered using the filter, the loss amount of blood is bigger, based on the structure, mistake The effective filtration area that ante-chamber surface area is much larger than filter membrane is filtered, causes to filter a part of blood of ante-chamber lower part delay, can not complete Filtering.Along with PVC film has larger ductility, inlet tube and outlet are parallel to filter membranous layer setting, cause local internal pressure Greatly, the rate of filtration is slow, or even blocks.And certain resistance is produced during filtering membrane filtration, cause to filter during filtering Ante-chamber remains the state of expansion, and filtering film component easily extrudes port of export conduit, and it is slack-off to ultimately result in the flow velocity of blood, even Port of export conduit is completely enclosed by filtering film component, causes to block.
The content of the invention
Goal of the invention:In order to overcome the deficiencies in the prior art, the present invention provides one kind and is based on trilamellar membrane heat seal simultaneously The three layers of PVC soft shell filters of side opening for preventing filtering from blocking.
Technical solution:To achieve the above object, three layers of PVC soft shell filters of side opening of the invention, including inlet tube, first Cephacoria, the second cephacoria, filter membranous layer, the first caudacoria, the second caudacoria and outlet, the filter membranous layer outer ring are heat seal portion;Described One cephacoria connects the heat seal portion of filter membranous layer, forms the filtering ante-chamber of closing with the front side of filter membranous layer, inlet openings are before first Film simultaneously connects filtering ante-chamber;Second cephacoria is connected to the front side of outlet, the second caudacoria on front side of filter membranous layer heat seal portion Including the company for connecting the ring part in filter membranous layer rear side heat seal portion and being connected on rear side of filter membranous layer heat seal portion on front side of outlet Socket part;The filtering back cavity of closing is formed between first caudacoria, the second caudacoria and filter membranous layer, outlet is set parallel to filter membranous layer Put and be opened on filtering back cavity.
Front side of the present invention and rear side correspond to the both sides of filter membranous layer respectively.Side where inlet tube is front side, its Connection is filtering ante-chamber;Outlet connection is filtering back cavity, its setting direction is parallel with filter membranous layer.Above-mentioned design facilitates soft The hanging of shell filter uses.
Filter membranous layer includes at least one layer of filter membrane and forms, and is under normal circumstances 10 ~ 20 tunics, by High frequency heating, by outer ring Pressing portions, and cut beyond the part in heat seal portion.First cephacoria and the second caudacoria exceed the part in filter layer heat seal portion Outer wing is formed, is connected with the common heat seal of the outer rim of the first caudacoria.Based on the design, the surface area for filtering ante-chamber is reduced, base It is suitable with filter area in sheet.
As the further optimization of the present invention, the inlet tube is square, before one end vertical connection filtering of inlet tube Chamber, the other end opening direction of inlet tube are and opposite with outlet opening direction parallel to filter membranous layer.
First cephacoria of the present invention, the second cephacoria, the first caudacoria, the second caudacoria are made of PVC material.Wherein, first Cephacoria and the second cephacoria are one layer of common PVC film.This tunic is by being heat sealing in filter membranous layer heat seal portion, the portion in heat seal portion Point be the first cephacoria, on front side of heat seal portion and connection outlet pipe for the second cephacoria.
Back cavity is filtered in order to prevent to be extruded be subject to filtering ante-chamber, the first caudacoria is affixed with filter layer, so as to influence Filter effect, supporting rack is equipped between first caudacoria and filter membranous layer.The supporting rack includes but not limited to plastics, silica gel, rubber Tubulose or club made of glue, metal material.Supporting rack is sealed against by high frequency heat seal, is fixed in filtering back cavity.
Beneficial effect:The present invention reduces the surface area of filter ante-chamber in the case where filter area is constant, filters the table of ante-chamber Area is equal to filter area, blood by filter membrane, is reduced blood loss completely;Filter ante-chamber surface area to reduce, expansion In the case that coefficient is identical with blood pressure, the degrees of expansion for filtering ante-chamber is reduced, so that reduce the extruding to port of export conduit, Make filtering more unobstructed, will not blockage phenomenon;Contrast original soft shell filter, the present invention is only with three layers of PVC film, for the production From the point of view of the characteristics of product mass production, the saving of raw material can greatly reduce cost input.
Brief description of the drawings
Fig. 1 is the structure diagram of existing four tunics soft shell filter;
Fig. 2 is the structure diagram of the present invention.
Embodiment
The present invention is further described below in conjunction with the accompanying drawings.
As shown in Fig. 2, a kind of three layers of PVC soft shell leukocyte depletion filters of side opening, including inlet tube 11, the first cephacoria 12, Two cephacorias 13, filter membranous layer 3, the first caudacoria 22, the second caudacoria 23 and outlet 21, filter membranous layer 3 is by 10 ~ 20 layers of leukocyte filter membranes layer Fold and pressing forms in periphery, the part of periphery pressing is heat seal portion 30.Inlet tube 11 is square, and one end of inlet tube 11 is hung down It is direct-connected by filtering ante-chamber 10, the other end opening direction of inlet tube 11 parallel to filter membranous layer 3, and with 21 opening direction phase of outlet Instead.The supporting rack 5 of silica gel hose support is equipped between first caudacoria 12 and filter membranous layer 3.Supporting rack 5 is close by its by high frequency heat seal Seal, be fixed in filtering back cavity 20.
First cephacoria 12 connects the heat seal portion 30 of filter membranous layer 3, and the filtering ante-chamber 10 of closing is formed with the front side of filter membranous layer 3, Inlet tube 11 is opened on the first cephacoria 12 and connects filtering ante-chamber 10;Second cephacoria 12 is connected from the front side in filter membranous layer heat seal portion 30 To the front side of outlet 21, the second caudacoria 23 includes the ring part 231 in 3 rear side heat seal portion 30 of connection filter membranous layer and from filter membrane The rear side in layer heat seal portion 30 is connected to the connecting portion 232 of the front side of outlet 21;First caudacoria 22, the second caudacoria 23 and filter membranous layer 3 Between form the filtering back cavity 20 of closing, outlet 21 sets parallel to filter membranous layer 3 and is opened on filtering back cavity 20.
First cephacoria 12 and the second caudacoria 23 form outer wing 4 beyond the part in filter layer heat seal portion 30, with the first caudacoria 22 Outer rim common heat seal connection.Based on the design, the surface area for filtering ante-chamber is reduced, substantially suitable with filter area.
First cephacoria 12 and the second cephacoria 13 are one layer of common PVC film.This tunic is fixed on filter membranous layer heat by heat seal In conjunction portion 30, the part in heat seal portion 30 is the first cephacoria 12, on front side of heat seal portion and connection outlet pipe for second Cephacoria 13.First cephacoria 12, the second cephacoria 13, the first caudacoria 22, the second caudacoria 23 are made of PVC material.
The above is only the preferred embodiment of the present invention, it should be pointed out that:For the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (4)

1. three layers of PVC soft shell filters of side opening, it is characterised in that:Including inlet tube, the first cephacoria, the second cephacoria, filter membranous layer, One caudacoria, the second caudacoria and outlet, the filter membranous layer outer ring are heat seal portion;The heat seal of the first cephacoria connection filter membranous layer Portion, forms the filtering ante-chamber of closing, inlet openings are in the first cephacoria and connect filtering ante-chamber with the front side of filter membranous layer;
The lower front in second cephacoria from filter membranous layer heat seal portion is connected to the front side of outlet, and the second caudacoria includes connection and filters The ring part top in heat seal portion and the back lower from filter membranous layer heat seal portion are connected to the connection on front side of outlet on rear side of film layer Portion;
The filtering back cavity of closing is formed between first caudacoria, the second caudacoria and filter membranous layer, outlet is set parallel to filter membranous layer Put and be opened on filtering back cavity;First cephacoria and the second cephacoria are one layer of common film;
Supporting rack is equipped between first caudacoria and filter membranous layer.
2. three layers of PVC soft shell filters of side opening according to claim 1, it is characterised in that:First cephacoria and second Caudacoria forms outer wing beyond the part in filter layer heat seal portion, is connected with the common heat seal of the outer rim of the first caudacoria.
3. three layers of PVC soft shell filters of side opening according to claim 1, it is characterised in that:The inlet tube is square, One end vertical connection filtering ante-chamber of inlet tube, the other end opening direction of inlet tube are opened parallel to filter membranous layer, and with outlet Mouth direction is opposite.
4. three layers of PVC soft shell filters of side opening according to any one in claim 1 ~ 3, it is characterised in that:Described One cephacoria, the second cephacoria, the first caudacoria, the second caudacoria are made of PVC material.
CN201510389005.2A 2015-07-03 2015-07-03 Three layers of PVC soft shell filters of side opening Active CN104998307B (en)

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CN104998307B true CN104998307B (en) 2018-05-11

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105396182B (en) * 2015-12-30 2018-04-17 南京双威生物医学科技有限公司 A kind of outlet offset soft shell filter

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526678A1 (en) * 1991-06-24 1993-02-10 Maco Pharma Sterilising bag for sterile filtration of blood and set of bags for collection of blood
CN1720070A (en) * 2002-12-02 2006-01-11 弗雷森纽斯血液护理德国有限责任公司 Filter
CN201040115Y (en) * 2007-03-30 2008-03-26 天津协和生物科技发展有限公司 Thin membrane type white blood cell filter
CN103623475A (en) * 2012-08-22 2014-03-12 上海输血技术有限公司 Leukocyte-depleted cell filter with multiple filtering units
CN204766754U (en) * 2015-07-03 2015-11-18 南京双威生物医学科技有限公司 Side opening three -layer PVC sabot filter

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101518687B1 (en) * 2010-09-21 2015-05-11 아사히 가세이 메디컬 가부시키가이샤 Blood processing filter and method for producing blood processing filter

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526678A1 (en) * 1991-06-24 1993-02-10 Maco Pharma Sterilising bag for sterile filtration of blood and set of bags for collection of blood
CN1720070A (en) * 2002-12-02 2006-01-11 弗雷森纽斯血液护理德国有限责任公司 Filter
CN201040115Y (en) * 2007-03-30 2008-03-26 天津协和生物科技发展有限公司 Thin membrane type white blood cell filter
CN103623475A (en) * 2012-08-22 2014-03-12 上海输血技术有限公司 Leukocyte-depleted cell filter with multiple filtering units
CN204766754U (en) * 2015-07-03 2015-11-18 南京双威生物医学科技有限公司 Side opening three -layer PVC sabot filter

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