CN104921833A - Dental instrument system with sensor - Google Patents
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- CN104921833A CN104921833A CN201410109704.2A CN201410109704A CN104921833A CN 104921833 A CN104921833 A CN 104921833A CN 201410109704 A CN201410109704 A CN 201410109704A CN 104921833 A CN104921833 A CN 104921833A
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Abstract
The invention provides a dental instrument system with a sensor. The dental instrument system comprises a dental instrument and at least one sensor, wherein the dental instrument is used for being arranged on at least tooth of a user; the at least one sensor is arranged on the dental instrument; the at least one sensor is configured to monitor physiological information of a user wearing the dental instrument. Further, the invention also provides a monitoring system which is used for receiving the monitored physiological information of the user in vitro and displaying the physiological information, or carrying out sound prompt, and therefore, dynamic measurement and monitoring of physiological information of a human body can be carried out by the dental instrument worn by the user.
Description
Technical field
Present invention relates in general to oral cavity technical field, specifically, the present invention relates to a kind of dental instruments system with sensor and utilize the physiologic information of this dental instruments system on human body to carry out the monitoring system measured.
Background technology
The dental instruments of mount type is adopted to carry out orthodontics and treat more extensive in the application in positive tooth field.The dental instruments of described mount type not only comprises traditional dentistry dentistry bracket, also comprises novel stealthy dental appliance.This stealthy dental appliance is made up of the elasticity transparent polymer material of safety, process of rescuing almost is completed other people in discovering, can not affect daily life and social activity; Wear because patient can pluck voluntarily, oral hygiene can conventional maintenance, and whole process of rescuing saves time and laborsaving.Therefore, at present without bracket invisalign method by increasing people is adopted.Above-mentioned stealthy dental appliance is one group and has the polymeric shells can holding the cavity of tooth in inside, after the correction of the tooth that the geometry of the cavity of its accommodation tooth and this appliance will reach, state/arrangement adapts, therefore by using a series of dental appliance to make tooth reorientate.
No matter be traditional dentistry dentistry bracket, or novel stealthy dental appliance group, all need on the tooth of user, to wear a period of time, such as 1-2.And the surrounding enviroment of tooth, namely contain a large amount of physiologic informations in oral environment.Such as, containing various trace elements in saliva, and modern scientific research proves, trace element plays an important role in human body, and its shortage is with superfluous of close concern to each other with the health of people.
It is multiple that the detection method of traditional trace element mainly contains " urine examination ", " breast inspection ", " blood examination ", " sending out inspection " etc.Relatively conventional has " blood examination " and " send out and examine " two kinds, but said method all needs patient to go to hospital by regularly taking sample to detect, and cannot realize in real time, examination and controlling easily.
Summary of the invention
Therefore, the present invention proposes a kind of dental instruments system with sensor and corresponding monitoring system, its dental instruments that patient can be utilized to wear, realize dynamic, examination and controlling easily for patient's oral environment.
Correspondingly, according to an aspect of the present invention, provide a kind of dental instruments system with sensor, it comprises: dental instruments, and it is for being arranged at least one tooth of user; And at least one is arranged on the sensor on described dental instruments; Wherein, at least one sensor described is configured to monitor the physiologic information of the user wearing described dental instruments.
Preferably, described dental instruments comprises stealthy dental appliance.Wherein, preferably, described stealthy dental appliance comprises at least one in projection, depression and aperture.And at least one in described projection, depression and aperture of at least one sensor setting described.
And as what replace, at least one sensor described is fixed on described stealthy dental appliance by bonding or welding manner.
As what replace, described dental instruments also comprises dentistry bracket.Wherein, preferably, described dentistry bracket comprises bow line and at least one support bracket, and described sensor setting is at least one support bracket described.
As what replace, described dental instruments can also comprise the facing without correction function.Wherein, preferably, the described facing without correction function comprises at least one in projection, depression and aperture, and at least one in described projection, depression and aperture of described sensor setting.
Preferably, at least one sensor described is configured to be suitable for monitoring at least one in following physiologic information: the micronutrient levels in the saliva of described user, enter the composition of food in the oral cavity of described user, the content of the specific protein in the saliva of described user, the oral temperature of described user, the blood oxygen concentration of described user, the glucose content in the saliva of described user, and the blood pressure of described user.
Preferably, described dental instruments system also comprises: microchip, and described microchip to be arranged on described dental instruments and to be connected with sensor.Wherein, preferably, described microchip comprises data recording equipment.
Preferably, described sensor is selected from: temperature sensor, digital imaging element, pressure transducer, blood oxygen transducer, biosensor and comprise its combination sensor.
According to another aspect of the present invention, additionally provide a kind of monitoring system, it comprises: dental instruments, and it is for being arranged at least one tooth of user; At least one is arranged on the sensor on described dental instruments, and wherein, at least one sensor described is configured to monitor the physiologic information of the user wearing described dental instruments; Microchip, it to be arranged in described dental instruments and to be connected with described sensor, and this microchip is configured to receive at least one first signal of sensor and is translated into secondary signal and sends; And being positioned at the external receiving equipment of user, it is for receiving described secondary signal.
Preferably, described receiving equipment also comprises a display unit, to provide the sound and/or visual information that represent described secondary signal.
According to the dental instruments system with sensor of the present invention and corresponding monitoring system, its dental instruments that user or patient can be utilized to wear, by being arranged at least one sensor on dental instruments, measure physiologic information (the such as temperature comprised in oral environment, blood pressure, trace element, glucose etc.), thus realize dynamic, the examination and controlling easily of the physiologic information for user or patient.
Accompanying drawing explanation
Above-mentioned and other feature of the present invention will by being described further below in conjunction with accompanying drawing and detailed description thereof.Should be understood that, these figures only show according to some exemplary embodiments of the present invention, therefore should not be considered to be limiting the scope of the invention.Unless stated otherwise, accompanying drawing needs not to be proportional, and wherein similar label represents similar parts.
Fig. 1 shows the schematic diagram of the dental instruments system according to the first detailed description of the invention of the present invention.
Fig. 2 shows the schematic diagram of the monitoring system according to a kind of detailed description of the invention of the present invention.
Fig. 3 shows the schematic diagram of the dental instruments system according to the second detailed description of the invention of the present invention.
Fig. 4 shows the schematic diagram of the dental instruments system according to the third detailed description of the invention of the present invention.
Detailed description of the invention
The accompanying drawing forming this description part is refer in the following detailed description.Description and the exemplary embodiment mentioned by accompanying drawing only for being illustrative object, are not intended to limit the scope of the invention.It will be understood by those skilled in the art that and also can adopt other embodiments many, and various change can be made to described embodiment, and do not deviate from purport of the present invention and protection domain.Should be understood that, to illustrate and illustrated various aspects of the present invention can arrange, replace, combine, are separated and design according to much different configurations at this, these different configurations are included in the present invention.
Refer now to Fig. 1, there is shown the dental instruments system according to the first detailed description of the invention of the present invention.Dental instruments 1 shown in Fig. 1 is one of them in a series of stealthy dental appliance, this stealthy dental appliance is made up of the elasticity transparent polymer material of safety, have the polymeric shells can holding the cavity of tooth in inside, after the correction of the tooth that the geometry of the cavity of its accommodation tooth and this appliance will reach, state/arrangement adapts.Generally speaking, a correcting process often needs a series of stealthy dental appliance 1 as shown in Figure 1.The wear time of each stealthy dental appliance is generally 1-3 week, preferably fortnight, and according to the actual needs of patient, whole correcting process often needs the stealthy dental appliance of 20-40.
Wherein, stealthy dental appliance can be divided into maxillary appliance and mandibular appliance, and wherein maxillary appliance is for being worn on the maxillary teeth of user, and mandibular appliance is for being worn on the mandibular teeth of user.No matter being maxillary appliance or mandibular appliance, is all composition structures of transparent sheet, so all can be divided into outer surface part and inner surface portion.Wherein the tooth of inner surface portion and user contacts, and " covering " is on tooth, and outer surface part then contacts with the oral environment of user.
And, if distinguished from the front and rear surfaces direction of tooth, the outer surface part of stealthy dental appliance can be divided into lip side external surface part 11 (when on the tooth that appliance is worn on user, lip side external surface part 11 is near the front surface of tooth, and and the lip of user is adjoining) and tongue side external surface part 12 (when on the tooth that appliance is worn on user, tongue side external surface part 12 near the rear surface of tooth, and and the tongue of user adjoining).And if always distinguish from the Vertical Square of tooth, the part corresponding to every tooth of stealthy dental appliance can be divided into cusp part 13, tooth body part 14 and gingival edge part 15.
Although the geometry of the cavity of the accommodation tooth of general stealthy dental appliance (the i.e. inner surface of stealthy dental appliance, stealthy dental appliance with a side surface of tooth phase close contact) and the correction of tooth that will reach of this appliance after state/arrangement adapt, and its outer surface (side surface contacted with oral environment of stealthy dental appliance) is generally smooth surface, but according to the present invention, at least one sensor 10 can be held by the stealthy dental appliance 1 designed with special " container ".Preferably, described sensor 10 is biological compatible micro-nano sensor.
Preferentially, form projection 17 (corresponding inner surface side can form corresponding depression in the outer surface side of the thin-walled of stealthy dental appliance 1, or inner surface side shape does not change), or form depression 18 (corresponding inner surface side can form corresponding projection in the outer surface side of the thin-walled of stealthy dental appliance 1, or inner surface side shape does not change), or the upper formation aperture 16 of the thin-walled at stealthy dental appliance 1, forms " container " region holding sensor.
It should be noted, although the above-mentioned projection 17 shown in Fig. 1, depression 18 and aperture 16 are all positioned at the lip side external surface part 11 of stealthy dental appliance 1, but as required, it also can be positioned at the tongue side external surface part 12 of stealthy dental appliance 1, and above-mentioned projection 17, depression 18 and aperture 16 can be positioned at the cusp part 13 of stealthy dental appliance, tooth body part 14 or gingival edge part 15.Its position can be chosen as required flexibly.Preferably, above-mentioned projection 17, depression 18 and aperture 16 are positioned at tooth body part 14 or the gingival edge part 15 of stealthy dental appliance 1.
The shape of the above-mentioned projection 17 of choose reasonable, depression 18 and aperture 16, makes it under the prerequisite worn and " coincide " with tooth phase not affecting dental appliance, plays the effect of accommodation sensor 10.
As shown in Figure 1, the sensor 10 for measuring the physiologic information comprised in oral environment of at least one can be set in the projection 17 of the outer surface of stealthy dental appliance, depression 18 and aperture 16.And corresponding to the type of measured physiologic information, described sensor 10 can be dissimilar sensor (such as temperature, blood pressure, trace element etc.), and according to the difference of the type of sensor 10, can be arranged on the diverse location of stealthy dental appliance 1.
It will be appreciated by those skilled in the art that, the quantity of above-mentioned projection 17, depression 18 and aperture 16 can only have one, also can be multiple.Such as, only can there is a projection 17 for one or more sensors 10 of accommodation, or only there is a depression 18 for one or more sensors 10 of accommodation, or only there is an aperture 16 for one or more sensors 10 of accommodation, or also can there is multiple projection 17, depression 18 and aperture 16 for one or more sensors 10 of accommodation.
According to an exemplary embodiment of the present invention, the manufacture process of above-mentioned stealthy dental appliance 1 is as follows: first make physical tooth model (such as making Gypsum Fibrosum tooth model by impression taking) according to the state of the current dental phenomenon of patient or tooth and perienchyma's (as gingiva, facial soft tissue) thereof, again this physical tooth model is scanned, to generate the virtual tooth model of the initial condition representing patient teeth.Next, the virtual tooth model original based on this and target is rescued for patient teeth, what set at least one rescues parameter, rescues parameter automatically form a series of progressively progressive orthodontic state (also can be described as the tooth arrangement model of target or the tooth arrangement model after rescuing) by computer system according to this original virtual tooth model and set at least one.Described a series of orthodontic state reflects carries out a series ofly rescuing the favourable change to tooth structure or arrangement after step to original tooth model.The corresponding tooth digitized data model of each orthodontic state, therefore can be obtained by computer system and store a series of tooth digitized data model.
After obtaining a series of tooth digitized data model, by rapid shaping process (such as laser fast forming SLA, layer separated growth LOM, selective laser sintering SLS, Fused Deposition Modeling FDM and 3 D-printing manufacture the quick molding methods such as 3DP), generate the tooth model (i.e. the formpiston of dental appliance) of physics according to the described tooth data model be layered.Then can based on the formpiston of described dental appliance, by hot-embossing equipment, the appliance diaphragm be made up of transparent polymer material is carried out hot forming on above-mentioned tooth model, to form housing, thus obtained dental appliance 1, in hot-forming process, by arranging given shape on the formpiston of dental appliance, appliance 1 can form corresponding projection 17.Further, further appliance is reprocessed, to form depression 18 and aperture 16.
In another kind of illustrative embodiments, can generate according to described tooth digitized data model the appliance digitized data model representing dental appliance shape.Because dental appliance is designed to have the geometry of the cavity holding tooth, namely it is consistent with on the jaw corresponding to appliance or many teeth substantially, can hold or close to the reverse shape copying every tooth.Namely based on the formpiston type of obtained representative orthodontic state, by the method for traditional computer digital animation, the method of such as computer-aided design (CAD), by offseting out from the crown surfaces of each tooth or distance about 0.05mm or more, obtain the digitized data model of the inner surface of the dental appliance (former type) that representative " coincide " with the basic phase of the outline of this orthodontic state.Preferably, as required, under the prerequisite that geometry and the dental phenomenon of the cavity of guarantee appliance match substantially, the shape of appliance 1 can be designed personalizedly.Namely can carry out fine adjustment to the digitized data model of the basic dental appliance that representative and the outline phase of this orthodontic state " are coincide ", design the shape of dental appliance 1 personalizedly, directly can form projection 17, depression 18 and aperture 16.Then utilize rapid shaping process, directly carry out " 3 D-printing " stealthy dental appliance 1 according to appliance digitized data model.
According to the first detailed description of the invention of the present invention, according to the concrete condition of user, stealthy dental appliance 1 can arrange one or more sensor 10, or the sensor 10 with combination function is set, to measure various physiologic information.Specific as follows:
According to an exemplary embodiment of the present invention, measured physiologic information is oral temperature, and accordingly, described sensor 10 comprises temperature sensor, such as thermocouple sensing element.Thermocouple sensing element is made up of the tinsel of two unlike materials, and structure is simple, and degree of accuracy is high, and range ability is wide.Its operation principle is: conductor (being called thermocouple wire material or the thermode) two ends of two kinds of different components are bonded into loop, when the temperature at abutment is different, will produce electromotive force in the loop, this phenomenon is called pyroelectric effect, and this electromotive force is called thermoelectrical potential.It is thermometric that thermocouple sensing element utilizes this principle to carry out exactly, so thermocouple sensing element is actually a kind of energy transducer, thermal power transfer is electric energy by it, and the variations in temperature corresponding according to the transformation calculations of electric energy, thus realize the measurement of temperature.It should be noted, thermocouple sensing element is a kind of embodiment of temperature sensor of the present invention, and temperature sensor of the present invention is not limited in thermocouple sensing element, can also comprise the temperature sensor of other types.
Learning that the variations in temperature of this human body is a kind of conventional thermometry by measuring oral temperature, such as, when hospital admission, often carry out temperature survey by clinical thermometer being put in Sublingual.So, by the temperature in monitoring human oral cavity, there is significance medically.But traditional oral temperature measurement method cannot accomplish real-time measurement, and the present invention is by set temperature sensor in the dental instruments worn at user, just can reach the object measured in real time.
When described sensor 10 is for temperature sensor, preferably, this temperature sensor is positioned at least one projection of the outer surface of stealthy dental appliance 1, depression or aperture, thus this temperature sensor can with oral environment close contact.Preferably, this temperature sensor is positioned at least one projection of the tongue side external surface part 12 of stealthy dental appliance, depression or aperture, thus this temperature sensor can with oral environment close contact, and not affect the appearance.
According to another illustrative embodiments of the present invention, measured physiologic information is the trace element in saliva, and accordingly, described sensor is trace element sensor.At medical domain, from the structure of human body, account for human total weight ten thousand/following person and be trace element.Need situation according to body to trace element, those are indispensable to maintenance organism normal activities, must by food intake and every day dietary needs amount be all called essential trace element at the trace element of below 100mg.These trace element, about 0.05% of percentage of liveweight, comprises ferrum, copper, zinc, chromium, cobalt, manganese, nickel, stannum, silicon, selenium, molybdenum, iodine, fluorine, vanadium etc. 14 kinds, although content is very little in vivo for these trace element, can play important physiological action.Though trace element is to human body particular importance, too much very fewly disease can be caused.
And research shows, also containing trace element in human saliva, the trace element amount contained by human body can be assessed equally by the amount detecting the trace element in saliva.Therefore, by in the dental instruments worn at user, trace element sensor is set (such as, trace element sensor based on electrochemical principle or atomic absorption spectrphotometry principle), just can reach the function measuring the trace element amount contained by human body in real time.
When described sensor 10 is trace element sensor, preferably, this trace element sensor is positioned at least one projection of the outer surface of stealthy dental appliance, depression or aperture, thus this trace element sensor can with the saliva close contact in oral environment.Preferably, this trace element sensor is positioned at least one projection of the close gingiva of the tongue side external surface part 12 of the stealthy dental appliance of lower jaw, depression or aperture, thus this sensor can with saliva close contact, increase sampling quantity, and not affect the appearance.
According to another illustrative embodiments of the present invention, measured physiologic information is the glucose in saliva.Accordingly, described sensor 10 is glucose sensor.Saliva is a kind of transudate of human body, and the concentration of glucose in saliva and blood sugar concentration exist very large dependency.There are some researches show, I, the permeability of the parotid gland basement membrane of type ii diabetes patient increases, and when blood sugar level rises, a large amount of glucose enters in saliva with salivation approach, and when blood sugar concentration declines, the content of the glucose in saliva also can decline thereupon.Monitor continuously so be expected to by the concentration of glucose in monitoring saliva the noinvasive realizing blood glucose.
In one embodiment, glucose sensor comprises 3 major parts: nanoscale twins, nano platinum particle and glucoseoxidase that Graphene is made.If nanometer sheet wherein imitates small roseleaf, every sheet petal all contains multiple stacking graphene layer.The edge of petal also suspended on incomplete chemical bond, and nano platinum particle can be attached to here.Nanometer sheet and nano platinum particle combine and can form electrode, and glucoseoxidase also can be attached on nano platinum particle subsequently.Conversion of glucose can be peroxide by enzyme, and produces a signal on electrode, thus the concentration of the glucose in saliva has been changed into current signal.
When described sensor 10 is glucose sensor, preferably, this glucose sensor is positioned at least one projection of the outer surface of stealthy dental appliance, depression or aperture, thus this glucose sensor can with the saliva close contact in oral environment.Preferably, this glucose sensor is positioned at least one projection of the close gingiva of the tongue side external surface part 12 of the stealthy dental appliance of lower jaw, depression or aperture, thus this sensor can with saliva close contact, increase sampling quantity, and not affect the appearance.
According to another illustrative embodiments of the present invention, measured physiologic information is the content of the specific protein in saliva, and accordingly, described sensor is biosensor.Research proves, generation and the development of a lot of disease can stay " chemical notation " in saliva.Determining various DNA (deoxyribonucleic acid) (DNA), antibody and other compound relevant with virus and bacteriological infection by analyzing patient's saliva, just can understand the state of an illness of patient.2008, the red Buddhist nun (Denny) etc. of American South University of California published an article point out in " protein science research magazine " [J Proteome Res2008,7 (5): 1994], has 1166 kinds of protein in the saliva of people.Have research to find successively subsequently, the levels such as the c reactive protein in people's saliva, α-1B glycoprotein, creatinine are relevant to cardiovascular disease, cancer, nephropathy etc.Such as, when the content of c reactive protein raises, the probability that people suffer from a heart complaint will increase, and Electrocardiography combines, rate of accuracy reached 95%.And, as far back as 2007, the researcher of U.S. M.D. Anderson (Anderson) Cancer center is just once at " international oncology's magazine " [Int J Oncol2007,30 (3): 743] upper report, in the saliva of head, neck squamous cell carcinoma patient, α-1B glycoprotein and complement factor B protein level significantly raise, and almost can't detect this two kinds of albumen in collator's saliva.Correspondingly, the level of the albumen such as Guang Protein S, the parotid secretion factor exists in collator's saliva, but can't detect in head, neck squamous cell carcinoma patient saliva.
Accordingly, the content of the target protein that can detect as required designs corresponding biosensor.Biosensor has developed into one of modern most important detection technique.Biosensor is primarily of two ingredients and biological identification element and signal adapter.Wherein biological identification element refers to have molecule distinguishability, can with the biological sensitive materials of test substance generation specific reaction, such as enzyme, antigen and antibody etc.And signal adapter is mainly used for bio-identification effect to be converted to the signal that can detect, that commonly uses at present has electrochemistry, optics, heat and quality analysis etc.In the present invention, preferably, the biosensor for detecting the content of target protein adopts the structure of chemotron.Determinand (the target protein in such as the present invention, such as α-1B glycoprotein) and biomolecule identification component (the corresponding antibody of target protein institute in such as the present invention, i.e. α-1B glycoprotein antibody) between there is uniqueness identification and binding characteristic, thus when target protein and corresponding antibody combine, generation electromotive force changes, thus by the size of the content size of target protein conversion in order to the signal of telecommunication.
According to the demand of user, different biosensors can be set.Such as, the sensor of cardiopathic user setting for detecting the c reactive protein content in saliva can be monitored for needing, and can for needing the sensor of the user of monitor head neck squamous cell carcinoma setting for detecting the α-1B glycoprotein Content in saliva.
When described sensor 10 is biosensor, preferably, this biosensor is positioned at least one projection of the outer surface of stealthy dental appliance, depression or aperture, thus this biosensor can with the saliva close contact in oral environment.Preferably, this biosensor is positioned at least one projection of close the gingiva of the tongue side external surface part 12 of the stealthy dental appliance of lower jaw, depression or aperture, thus this sensor can with saliva close contact, increase sampling quantity, and not affecting the appearance.
According to another illustrative embodiments of the present invention, described sensor is digital imaging element, such as cmos imaging element, and it can be used for measuring the composition of food entering user oral cavity.Preferably, at least one projection that described cmos imaging element is arranged on the close cusp of the tongue side external surface part 12 of the stealthy dental appliance of lower jaw or aperture, thus this sensor can detect the composition of food information being entered esophagus by throat.
Further, according to another illustrative embodiments of the present invention, described sensor 10 is pressure transducer or blood oxygen transducer, and the physiologic information detected is blood pressure information or blood oxygen information.
The gingiva of human body is distributed with abundant capillary network, and the bottom of stealthy dental appliance 1 abuts against on gingiva position, pressure value and/or the oxygen content of the blood capillary on gingiva therefore can be measured by arranging pressure transducer or blood oxygen transducer on stealthy dental appliance 1.
In one exemplary embodiment, adopt, on stealthy dental appliance 1, blood oxygen transducer is set to measure oxygen content.Oxygen content also claims blood oxygen saturation, blood oxygen saturation (SO2) is the percentage ratio that the capacity of the HbO2 Oxyhemoglobin (HbO2) combined by oxygen in blood accounts for whole combinative hemoglobin (Hb) capacity, the i.e. concentration of blood oxygen in blood, it is the important physiological parameter of breath cycle.And functional oxygen saturation is HbO2 concentration and the ratio of HbO2+Hb concentration, be different from percent shared by HbO2 Oxyhemoglobin.Therefore, monitor blood oxygen saturation (SaO2) to estimate the oxygenate of lung and hemoglobin oxygen carrying capacity.Numerous disease can cause the shortage of oxygen supply, and this will directly affect the eubolism of cell, and the serious life that also can threaten people, so the Real-Time Monitoring of arterial blood oxygen concentration is extremely important in clinical rescue.
Oxygen saturation measurement be based on blood to the absorbtivity of light with beat and the principle that changes measure.Basic research shows, HbO2 Oxyhemoglobin and non-HbO2 Oxyhemoglobin have different absorbances to different wave length incident illumination.When the constant light λ 1 with two kinds of specific wavelengths, λ 2 irradiate blood vessel, if (HbO2, Hb such as to have herein at the absorption characteristic suitably to select lambda1-wavelength λ 1, i.e. about 805nm), use Lambert-Beer's law and according to the approximate formula that the definition of oxygen saturation can release arterial oxygen saturation be:
SaO2=ABQ，
In formula: Q is the ratio of the absorbance change of two kinds of wavelength (HbO2, Hb), and A, B are constant, relevant with sensor construction and measuring condition.
According to a kind of exemplary embodiments of the present invention, blood oxygen transducer is made up of luminescent device and receiving device.Luminescent device is made up of the infrared light emission pipe of wavelength to be the HONGGUANG of 660nm and wavelength be 940nm.Photoreceptor adopts light sensitive diode, converts the incident optical signal received to the signal of telecommunication by it.When oximeter runs, timesharing drive circuit allows two light emitting diodes by certain time interval and distinguishes with lower dutycycle luminous, the strong and weak ratio of the transillumination received according to optical diode luminous intensity and photocell can calculate whole blood absorption rate a660 and a940 respectively, then coefficient A and B of Binding experiment demarcation, to substitute in aforementioned formula, just can calculate to obtain the numerical value of blood oxygen saturation.
When described sensor 10 be blood oxygen or pressure transducer time, preferably, this sensor is positioned at least one projection of the close gingiva of the tongue side external surface part 12 of the stealthy dental appliance of the upper jaw or lower jaw, depression or aperture, thus this sensor with gingiva close contact to measure, and can not affect the appearance.
Although, be described above and form projection, depression or aperture to hold sensor on stealthy dental appliance 1, but the surface that also sensor 10 can be fixed to stealthy dental appliance 1 by multiple methods such as such as bonding, welding realizes the step of " by sensor setting in dental instruments ".Preferably, after on surface sensor 10 being applied to stealthy dental appliance 1, then the protective layer spraying one deck bio-capacitivity can not come off in the oral cavity to protect sensor.
In sum, according to the present invention, according to the concrete condition of user, stealthy dental appliance 1 can arrange one or more sensor 10, or the sensor 10 with combination function is set, to measure various physiologic information.Described physiologic information includes but not limited to: the micronutrient levels in the saliva of user, enter the composition of food in the oral cavity of user, the content of the specific protein in the saliva of user, the oral temperature of user, the blood oxygen concentration of user, glucose content in the saliva of user, and the blood pressure of described user.And setting position can be selected according to the type of each sensor.
Further, the present invention also provides a kind of monitoring system, carry out showing or sound prompting for the physiologic information that monitors in the external reception of user, thus make the dental instruments worn by user to carry out kinetic measurement and the monitoring of Human Physiology information.Fig. 2 is the schematic block diagram of the monitoring system 2 according to a kind of detailed description of the invention of the present invention.
Wherein, dental instruments, stealthy dental appliance 1 such as, is provided with further one or more microchip 20 and (also claims to receive microchip, such as, micro integrated circuit), this microchip 20 can comprise power supply (in figure depending on) and carry out work with driving sensor 10.Further, preferably, this microchip 20 also can comprise data recording equipment 240, is used for the information that storage sensor 10 records.Preferably, this microchip 20 also can comprise: signal conditioner 210 and multiplexer 220.Signal conditioner 210 also produces for providing energy for sensor 10 signal received from this sensor 10.Multiplexer 220 is then for combining the information being received from large quantity sensor 10.Described microchip 20 also with sensor setting on same position, also can be able to be arranged on adjacent position, is connected with crossing microelectronic circuit.Similar with sensor, microchip 20 also can be contained in projection, depression or aperture, or also can be fixed on the surface of dental instruments by multiple methods such as such as bonding, welding.
Further, preferably, this microchip 20 also can comprise: radio transmitters 230, for transmitting the information being received from one or more sensors 10.When one or more sensor 10 measures specific physiologic information, this information is sent on multiplexer 220 by described signal conditioner 210, and be sent on data recording equipment 240 and radio transmitters 230, collected information (being denoted as the first signal) stores by this data recording equipment 240, and information is sent in the receiving equipment 250 be connected with computer (not shown) by this radio transmitters 230.That is, receiving equipment 250 can receive data (being denoted as secondary signal) from microchip 20.In addition, selectable, in other embodiments, radio transmitters 230 can replace by hardware connection mode.
Therefore, according to a kind of detailed description of the invention of the present invention, additionally provide a kind of monitoring system, it comprises: dental instruments (such as stealthy dental appliance 1), and it is for being arranged at least one tooth of user; At least one is arranged on the sensor 10 on described dental instruments, microchip 20, it to be arranged in described dental instruments and to be connected with described sensor 10, and this microchip 20 is configured to receive at least one first signal of sensor 10 and is translated into secondary signal and sends; And being positioned at the external receiving equipment of user 250, it is for receiving described secondary signal.
As shown in Figure 2, when one or more sensor 10 receives information, this information is sent on multiplexer 220 by described signal conditioner 210, and be sent on data recording equipment 240 and radio transmitters 230, this data recording equipment 240 is by the first collected signal storage on microchip 20, and secondary signal is sent in receiving equipment 250 by this radio transmitters 230.
Clinician or user can use this receiving equipment 250 to upload the data obtained from the one or more sensors 10 on dental instruments (such as stealthy dental appliance 1).Subsequently, described receiving equipment 250 comprises display device (not shown) further, and it, for based on by the data handled by software, provides readable information Xiang doctor or user.This readable information can comprise the discrete physiologic information value that each sensor 10 obtains.This readable information can also comprise the numerical value chart obtained from user in certain a period of time.It can also provide warning message, namely sends unsafe condition signal, signal as excessively high in temperature.In addition, replace in the relevant discrete numerical readout of each sensor 10, this readable information can be simply to represent healthy or unsound situation instruction.
So in one exemplary embodiment, the part with normal value is shown as green, and the part exceeding normal value shows as yellow, other parts well beyond normal value then can show as redness.According to clinical data, predetermined threshold normal can be programmed in microchip 20, or be selected by receiving equipment 250 or select from other computers be connected with receiving equipment 250.
In one embodiment, described microchip 20 and data recording equipment 240 can comprise the customizing messages of the dental instruments that manufacturer provides, the numbering of such as dental instruments and the type etc. of sensor 10, the calibration data for each sensor 10 also can comprise wherein.In addition, this microchip 20 and data recording equipment 240 can comprise the historical readings of each sensor 10.This microchip 20 can also be programmed and to be processed the data of sensor 10.Correspondingly, in a preferred embodiment, described receiving equipment 250 can carry out minimal process to data or can only show those by microchip 20 processed and the data stored by data recording equipment 240.As the embodiment that is replaced, described receiving equipment 250 can receive initial data and process largely initial data.
Subsequently, the information on this receiving equipment 250 can be sent to further on other computers or server so that longer-term storage or be for further processing as required.
In some embodiments, described microchip 20 can be programmed for and open and close some day recorded information with some time only in one day or a middle of the month with predetermined time interval.When this microchip 20 is battery-powered, this equipment may be used for preserving electric energy.Selectively, this microchip 20 also can Information Monitoring continuously.This is favourable for monitoring continuously.
Selectable, described receiving equipment 250 can be arranged in the family of the patient being provided with above-mentioned dental instruments or in office, and preferably, this receiving equipment 250 can be the portable electric appts that user is carried with, such as mobile phone.Described microchip 20 can be configured to when some situation occurs wirelessly transmission signal to receiving equipment 250.Such as, sense that temperature raises at described microchip 20, it will send alarm signal to this receiving equipment 250, and then this receiving equipment 250 will send acoustic warning signal to user.Same, based on the signal measured by other sensor 10, also similar warning message can be produced.The alarm signal that receiving equipment 250 receives also can send doctor to by the Internet by this receiving equipment 250 again, thus this doctor can contact with user at once.
In one embodiment, described microchip 20 adopts battery to carry out energy supply.As what replace, described microchip 20 can adopt principle of induction to provide energy.According to this embodiment, be connected by a coil with the microchip 20 on dental instruments, another coil is embedded in other external devices of user.These other devices can be described receiving system.Magnetomotive force in coil outside patient body can produce magnetomotive force in the coil in dental instruments.Available remote energy source, as ultrasonic unit excites induction coil.This device can, for microchip 20 provides energy as transformer, thus can be avoided using battery.
Although hereinbefore, the present invention is described for stealthy dental appliance, but those of ordinary skill in the art should be realized that, can also adopt the dental instruments of other mount type in the present invention, such as dentistry bracket, the facing etc. that do not possess correction function are implemented.
Fig. 3 shows the schematic diagram of the dental instruments system according to the second detailed description of the invention of the present invention, in this second detailed description of the invention, wherein have employed dentistry bracket come " carrying " sensor and/or microchip.
As shown in Figure 3, dentistry bracket 3 comprises the bracket support 31 be respectively fixed on single tooth tooth, and it is fixed by given strap or is fixed on tooth by binding agent.After on the tooth that bracket support 31 is fixed to the upper jaw or lower jaw, then resilience arch wire 32 is placed in or lower bracket support archwire slot in, effectively to bind.
According to the present invention, at least one sensor 10 can be held by the bracket support 31 designed with special " container " region.Preferentially, form hollow protrusions at the outer surface of bracket support 31, form " container " region holding sensor.And by the shape of the above-mentioned projection of choose reasonable, make it under the prerequisite worn not affecting bracket support 31, play the effect holding sensor 10.
The surface that also sensor 10 can be fixed to bracket support 31 by multiple methods such as such as bonding, welding realizes the step of " by sensor setting in dental instruments ".Preferably, after on surface sensor 10 being applied to one or more bracket support 31, then the protective layer spraying one deck bio-capacitivity can not come off in the oral cavity to protect sensor.
With similar in the first detailed description of the invention, according to the concrete condition of user, dentistry bracket 3 can arrange one or more sensor 10, or the sensor 10 with combination function is set, to measure various physiologic information.Described physiologic information includes but not limited to: the micronutrient levels in the saliva of user, enter the composition of food in the oral cavity of user, the content of the specific protein in the saliva of user, the oral temperature of user, and the glucose content in the saliva of user, no longer repeat at this.
And, with similar in the first detailed description of the invention, (it can be arranged on on the same bracket support residing for sensor 10 described dentistry bracket can also to be arranged one or more microchip 20, also can be arranged on the bracket support that is different from residing for sensor 10), and further, preferably, this microchip 20 also can comprise: radio transmitters, for transmitting the information accepted from one or more sensor.Information is sent in the receiving equipment be connected with computer by this radio transmitters.Receiving equipment can receive data from microchip 20, thus composition monitoring system.Specific descriptions about microchip 20 and monitoring system with reference to the first detailed description of the invention, no longer can repeat at this.
And Fig. 4 shows the schematic diagram of the dental instruments system according to the third detailed description of the invention of the present invention.
According to the present invention, at least one sensor can also be arranged in other dental instrumentss.Here, other dental instrumentss can comprise the protectiveness facing etc. without correction function.These general facings itself do not have correction function, and itself does not possess elasticity, therefore can not apply Orthodontic force to tooth, but it may be used for taking care of one's teeth, especially can be worn over the carrying out of patient decayed tooth treatment tooth outside to take care of one's teeth.This kind of facing without correction function both can use metal to make, and transparent macromolecular material also can be used to make.Preferably, utilize transparent elastic modelling quantity be zero or the less macromolecule resin material of elastic modelling quantity prepare the facing that this type of does not have correction function.The tooth numbers that the facing of this kind of protectiveness can be protected as required and distribution design are various shape.Such as, Fig. 4 shows the facing 4 only needing to protect single particular tooth.
With similar in the first detailed description of the invention, can according to the concrete condition of user, the facing 4 not possessing correction function forms " container " (such as: projection 41) to hold one or more sensor 10, or the sensor 10 with combination function is set, to measure various physiologic information.Described physiologic information includes but not limited to: the micronutrient levels in the saliva of user, enter the composition of food in the oral cavity of user, the content of the specific protein in the saliva of user, the oral temperature of user, and the glucose content in the saliva of user, no longer repeat at this.
Further, with similar in the first detailed description of the invention, described " container " for holding sensor 10 both can be projection, also can be depression or aperture.
Although, preferably, the facing 4 not possessing correction function forms projection, depression or aperture to hold sensor 10, but the surface that also sensor 10 can be fixed to by multiple methods such as such as bonding, welding the facing 4 not possessing correction function realizes the step of " by sensor setting in dental instruments ".Preferably, after on surface sensor 10 being applied to the facing 4 not possessing correction function, then the protective layer spraying one deck bio-capacitivity can not come off in the oral cavity to protect sensor 10.
Further, with similar in the first detailed description of the invention, the described facing 4 not possessing correction function can also arrange one or more microchip 20, and further, preferably, this microchip 20 also can comprise: radio transmitters, for transmitting the information accepted from one or more sensor.Information is sent in the receiving equipment be connected with computer by this radio transmitters.Receiving equipment can receive data from microchip 20, thus composition monitoring system.Specific descriptions about microchip 20 and monitoring system with reference to the first detailed description of the invention, no longer can repeat at this.
Although the present invention is illustrated for stealthy dental appliance, dentistry bracket and the facing without correction function, but the dental instruments in the present invention is not limited thereto, dental instruments in the present invention covers and allly can be worn at having correction function or not having equipment or the equipment of correction function on tooth.
Although disclose various aspects of the present invention and embodiment at this, other aspects and embodiment are also apparent to those skilled in the art.Various aspects disclosed herein and embodiment are only for illustration of object, and unrestricted object.The invention is intended to any and all modifications and the modification that cover each embodiment of the present invention.Protection scope of the present invention and purport are determined by means of only accompanying claims.
Equally, each chart can illustrate exemplary architecture or other configurations of disclosed method and system, and it contributes to understanding the Characteristic and function that can be included in disclosed method and system.Claimed invention is not limited to shown exemplary architecture or configuration, and desired feature can realize with various alternative architecture and configuration.In addition, for flow chart, functional descriptions and claim to a method, square frame order given here should not be limited to be implemented with the various embodiments performing described function, unless explicitly pointed out within a context with same order.
Unless otherwise expressly stated, term used herein and phrase and variant thereof all should be interpreted as open, instead of restrictive.In some instances, such as the autgmentability vocabulary that " one or more ", " at least ", " but being not limited to " are such and the appearance of phrase or other similar terms should not be construed as in the example may not having this autgmentability term intention or need to represent the situation of constriction.
Claims (20)
1., with a dental instruments system for sensor, comprising:
Dental instruments, it is for being arranged at least one tooth of user; And
At least one is arranged on the sensor on described dental instruments; Wherein, at least one sensor described is configured to monitor the physiologic information of the user wearing described dental instruments.
2. system according to claim 1, is characterized in that, described dental instruments comprises stealthy dental appliance.
3. system according to claim 2, is characterized in that, described stealthy dental appliance comprises at least one in projection, depression and aperture.
4. system according to claim 3, is characterized in that, at least one in described projection, depression and aperture of at least one sensor setting described.
5. system according to claim 1, is characterized in that, at least one sensor described is fixed on described stealthy dental appliance by bonding or welding manner.
6. system according to claim 1, is characterized in that, described dental instruments comprises dentistry bracket.
7. system according to claim 6, is characterized in that, described dentistry bracket comprises bow line and at least one support bracket, and described sensor setting is at least one support bracket described.
8. system according to claim 1, is characterized in that, described dental instruments comprises the facing without correction function.
9. system according to claim 8, is characterized in that, the described facing without correction function comprises at least one in projection, depression and aperture, and at least one in described projection, depression and aperture of described sensor setting.
10. system according to claim 1, it is characterized in that, at least one sensor described is configured to be suitable for monitoring at least one in following physiologic information: the micronutrient levels in the saliva of described user, enter the composition of food in the oral cavity of described user, the content of the specific protein in the saliva of described user, the oral temperature of described user, the blood oxygen concentration of described user, glucose content in the saliva of described user, and the blood pressure of described user.
11. systems according to claim 1, comprise: microchip further, and described microchip to be arranged on described dental instruments and to be connected with described sensor.
12. systems according to claim 11, is characterized in that, described microchip comprises data recording equipment.
13. systems according to claim 1, is characterized in that, described sensor is selected from: temperature sensor, digital imaging element, pressure transducer, blood oxygen transducer, biosensor and comprise its combination sensor.
14. 1 kinds of monitoring systems, it comprises:
Dental instruments, it is arranged at least one tooth of user;
At least one is arranged on the sensor on described dental instruments, and wherein, at least one sensor described is configured to monitor the physiologic information of the user wearing described dental instruments;
Microchip, it to be arranged on described dental instruments and to be connected with described sensor, and this microchip is configured to receive at least one first signal of sensor and is translated into secondary signal and sends; And
Be positioned at the receiving equipment that user is external, it is for receiving described secondary signal.
15. systems according to claim 14, is characterized in that, described receiving equipment comprises a display unit, to provide the sound and/or visual information that represent described secondary signal.
16. systems according to claim 14, is characterized in that, described microchip comprises data recording equipment.
17. systems according to claim 14, is characterized in that, described dental instruments comprises stealthy dental appliance.
18. systems according to claim 17, it is characterized in that, described stealthy dental appliance comprises at least one in projection, depression and aperture, and at least one sensor described and microchip are arranged at least one in described projection, depression and aperture.
19. systems according to claim 14, it is characterized in that, at least one sensor described is configured to be suitable for monitoring at least one in following physiologic information: the micronutrient levels in the saliva of described user, enter the composition of food in the oral cavity of described user, the content of the specific protein in the saliva of described user, the oral temperature of described user, the blood oxygen concentration of described user, glucose content in the saliva of described user, and the blood pressure of described user.
20. systems according to claim 14, is characterized in that, described sensor is selected from: temperature sensor, digital imaging element, pressure transducer, blood oxygen transducer, biosensor and comprise its combination sensor.
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| CN201410109704.2A CN104921833A (en) | 2014-03-21 | 2014-03-21 | Dental instrument system with sensor |
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| CN201410109704.2A CN104921833A (en) | 2014-03-21 | 2014-03-21 | Dental instrument system with sensor |
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| WO2022100473A1 (en) * | 2020-11-11 | 2022-05-19 | International Business Machines Corporation | Embedded oral sensor platform |
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| WO2022167189A1 (en) * | 2021-02-03 | 2022-08-11 | Ivoclar Vivadent Ag | Dental sensor system for attaching a dental sensor |
| CN113413223B (en) * | 2021-06-09 | 2022-05-10 | 浙江大学 | Functional appliance capable of dynamically monitoring correction force value based on flexible electronic system and preparation method thereof |
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