CN104873579B - The application of Jia Betel extracts - Google Patents
The application of Jia Betel extracts Download PDFInfo
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- CN104873579B CN104873579B CN201510266166.2A CN201510266166A CN104873579B CN 104873579 B CN104873579 B CN 104873579B CN 201510266166 A CN201510266166 A CN 201510266166A CN 104873579 B CN104873579 B CN 104873579B
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Abstract
The present invention relates to cultivation field, the application of Jia Betel extracts is disclosed.The Jia Betel extracts not only can play direct toxic action to coccidia polypide, but also can strengthen Abwehrkraft des Koepers, and the damage to sick fowl body is small.Using preparation made from Jia Betel extracts, can be directly appended to as feed addictive in feed, it is easy to use, easy to control dosage, play the role of preventing global-worm illness.
Description
Technical field
The present invention relates to cultivation field, the application of Yong Yu Jia Betel extracts is particularly related to.
Background technology
Global-worm illness is a kind of to the prejudicial parasitic disease of poultry intestinal tract.Death loss is 20% above is very universal shows
As.Chicken coccidiasis (Coccidiosis in Chicken) is a kind of extremely strong normal of incidence is wide, lethality is higher harmfulness
Parasitic disease is seen, caused by unicellular parasite Eimeria (Amy ear).The life cycle of Eimeria is about 4-7 days.
The life of Eimeria is begun to after the egg capsule of activity is searched for food by chicken to be swallowed.Its main parasitic, can in chicken body enteron aisle position
Cause chick growth after recovering to be obstructed, reduce adult hen egg laying performance, seriously affect chicken body weight gains.In Globidium, tender Chinese mugwort
Mei Er coccidias pathogenicity is most strong, distribution is most wide, it can invade chicken cecal epithelium cell, cause caecum height swelling, and intestinal wall thickens,
Enteral is full of blood or blood clot.At present, prevention chicken coccidiasis mainly uses chemicals, but it is also easy to produce drug resistance, causes
Medicament residue, has seriously affected the safety of food.
Appliable plant extract for preventing and treating disease, have the advantages that to be not likely to produce drug resistance, toxic side effect it is small, meanwhile, very much
Plant extracts has concurrently at the same time to be promoted body growth, improves the advantages that immunity of organisms.Therefore, appliable plant extract reduce or
Substitute the hot spot that chemicals is today's society research.Poultry infection coccidia after, generally occur it is apathetic, loss of appetite,
The symptoms such as diarrhea, severe patient, which can discharge, is mixed with blood even whole blood loose stool, and egg capsule is can detect in excrement.Coccidia is not only to stomach and intestine
Road causes greatly to damage, and can also destroy the immune system of poultry, reduces immunity.Since chemicals mainly passes through liver generation
Thank, prevent global-worm illness using chemicals, although preferable prevention effect can be reached, a setting loss can be caused to liver
Wound, have impact on the constitution of poultry.
Global-worm illness is prevented using natural plants, relevant report also occurs.As Chinese invention patent CN104522320A is public
A kind of natural plants anticoccidial feed addictive and its application have been opened, various plants extract is added into feed and is used, has been had
Have suppression kill worm, strengthen immunity, repair intestines and stomach the effect of.
Jia Betel (Pipe Sarmentosum Roxb.) are Piperaceae category (Piperaceae) plant, are distributed widely in print
The ground such as degree, Vietnam, Indonesia, Malaysia and South China mainland.Happiness is born in mountain valley thick forest, by rubber forest Zhong Huo villages
Moist shady place.Jia Betel nature and flavor, it is micro-pungent, temperature, nontoxic, there is warming spleen and stomach for dispelling cold, expelling wind and removing dampness, swelling and pain relieving and other effects.It can be used for
Treatment toothache, blood arrow sore, and ovum gallinaceum is cooked can treat malaria, decocting is taken orally and external curing tinea pedis disease.It can also be used for treatment stomach
Abdomen tremble with fear pain, cough due to wind-cold evil, nephritic dropsy, decoction or again amount infusing drugs in wine take outer liniment for treatment arthralgia pain due to rheumatism, traumatic injury orally.Stem, Ye Shui
Immersion liquid has inhibitory action to staphylococcus aureus, shigella flexneri etc.., Jia Betel also have antipyretic-antalgic, anti-inflammatory, drop at the same time
The effect such as bone healing after hypoglycemia, anti-oxidant and promotion fracture.Jia Betel extracts have been used for preparing killing pests and suppressing bacteria agent, as in
False Betel extracts are used to prepare pesticide-germicide microemulsion by state patent of invention CN102038007B, to prodenia litura, rubber pair pearl wax
A red-spotted lizard, radish aphid, bajiao banana anthrax bacteria and rubber anthrax bacteria have good prevention effect.
The content of the invention
The present invention provides the new application of Jia Betel extracts, that is, is applied to the preparation for preparing prevention global-worm illness.
The technical proposal of the invention is realized in this way：
A kind of application of Jia Betel extracts on the preparation for preparing prevention global-worm illness.
Further, the Jia Betel extracts are used to prepare the preparation of prevention coccidiosis of domestic fowls.
Further, the poultry is chicken.
Further, the preparation method of the Jia Betel extracts uses supercritical carbon dioxide extraction method, and extraction conditions are：It is false
It is 20-40 mesh that Betel cauline leafs, which are crushed to granularity, and extracting pressure 15-40MPa, extraction temperature is 35-60 DEG C, and carbon dioxide flow is
40-60L/h, extraction time 1.0-3h.
The preparation of Yi Zhong Betel extracts, including following component：Jia Betel extracts and carrier.
Further, the Jia Betel extract formulations include the component of following mass fraction：1-5 parts of Jia Betel extracts, carry
1-5 parts of body.
Further, the carrier is silica or calcium carbonate.
Further, the preparation method of the Jia Betel extracts uses supercritical carbon dioxide extraction method, and extraction conditions are：It is false
It is 20-40 mesh that Betel cauline leafs, which are crushed to granularity, and extracting pressure 15-40MPa, extraction temperature is 35-60 DEG C, and carbon dioxide flow is
40-60L/h, extraction time 1.0-3h.
A kind of application of Jia Betel extract formulations on the feed for preparing prevention global-worm illness.
Further, additive amount of the Jia Betel extract formulations in feed is 200-600mg/kg.
Beneficial effects of the present invention：
Jia Betel extracts contain the components such as asarone, cinnamic acid, myristicin, carypohyllene, phellandrene, alkaloid, not only
Direct toxic action can be played to coccidia polypide, also with anti-inflammatory, improve immunity, can actively transfer immunity of organism machine
Can, the damage to sick fowl body is reduced, is conducive to disease fowl body recovery function.
Jia Betel extracts are in oily, and viscosity is larger, is added in feed, not only easily cause feed agglomerate, poultry feeding
Inconvenience, it is apt to deteriorate, and also additive amount is difficult to control, it is difficult to operates.The , Jia Betel of the present invention Jiang after Jia Betel extracts are mixed with carrier
Extract can be adsorbed onto on carrier, and the preparation of powdery is made, and can be directly appended in feed, be played as feed addictive
Prevent the effect of global-worm illness, and be easy to the different control additive amounts of degree according to coccidium infection, using convenient.Jia Betel extracts
The resistance to the action of a drug is not likely to produce after natural plants, feeding, body will not be damaged, feed addictive can be used as long-term
Feeding, plays the role of preventing coccidia.
Embodiment
Below in conjunction with the embodiment of the present invention, the technical solution in the present invention is clearly and completely described, it is clear that
Described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.Based on the implementation in the present invention
Example, those of ordinary skill in the art's all other embodiments obtained without creative efforts, belongs to
The scope of protection of the invention.
Embodiment 1
The preparation method of Jia Betel extracts uses supercritical carbon dioxide extraction method, and extraction conditions are：Jia Betel cauline leafs crush
It is 20 mesh to granularity, extracting pressure 15MPa, extraction temperature is 35 DEG C, carbon dioxide flow 40L/h, and extraction time is
1.0h, is made oily Jia Betel extracts.
Jia Betel extract 10g obtained above are taken, add carrier silicas 10g, after mixing, that is, Jia Betel is made and carry
Take the preparation of thing.Jia Betel extract formulations obtained above can be directly appended in feed as feed addictive, and prevention is made
The feed of global-worm illness., Jia Betel extract formulations are directly appended to feed according to the additive amount of 200mg/kg during preparing feed
In, it is convenient to control additive amount, feed will not be caused to lump.
Embodiment 2
The preparation method of Jia Betel extracts uses supercritical carbon dioxide extraction method, and extraction conditions are：Jia Betel cauline leafs crush
It is 30 mesh to granularity, extracting pressure 20MPa, extraction temperature is 50 DEG C, carbon dioxide flow 50L/h, extraction time 2h,
Oily Jia Betel extracts are made.
Jia Betel extract 10g obtained above are taken, add carrier silicas 50g, after mixing, that is, Jia Betel is made and carry
Take the preparation of thing.Jia Betel extract formulations obtained above can be directly appended in feed as feed addictive, and prevention is made
The feed of global-worm illness., Jia Betel extract formulations are directly appended to feed according to the additive amount of 400mg/kg during preparing feed
In, it is convenient to control additive amount, feed will not be caused to lump.
Embodiment 3
The preparation method of Jia Betel extracts uses supercritical carbon dioxide extraction method, and extraction conditions are：Jia Betel cauline leafs crush
It is 40 mesh to granularity, extracting pressure 40MPa, extraction temperature is 60 DEG C, carbon dioxide flow 60L/h, extraction time 3h,
Oily Jia Betel extracts are made.
Jia Betel extract 50g obtained above are taken, add carrier silicas 10g, after mixing, that is, Jia Betel is made and carry
Take the preparation of thing.Jia Betel extract formulations obtained above can be directly appended in feed as feed addictive, and prevention is made
The feed of global-worm illness.The additive amount of , Jia Betel extract formulations during feed according to 600mg/kg is prepared, as feed addictive
It is directly appended in feed, it is convenient to control additive amount, feed will not be caused to lump.
Prevention effect of the Jia Betel extracts of the present invention to chicken coccidiasis
Test site, Ji Lan, wire mesh cage are uniformly disinfected before the test.
It is more sensitive to coccidia since cock resistance is low compared with hen, therefore choose health similar in 270 1 age in days weight
Wenchang, hainan cock, using single factor test completely randomized design, is randomly divided into T1 groups, T2 groups, T3 groups, T4 groups, T5 groups, T6 groups 6
Group, every group of 45 chickens, subfield raising, free choice feeding.
T1 groups, T2 groups, T3 groups are control group, and feeding is not added with the full price chicken feed of any coccidiostat, T4 groups, T5
Group, T6 groups are experimental group, respectively the full price chicken feed of Jia Betel extract formulations obtained by 3 embodiments of feeding addition.15 days
During age, 30 chickens are randomly selected from every group, sub-cage rearing, in addition to T1 groups feed physiological saline, every chicken of remaining each group connects
Kind Eimeria Tenella Sporulated Oocysts 1 × 105It is a.The 3rd day after coccidium infection, it is molten that T3 groups add diclazuril in drinking-water
Liquid, continuously drinks 5 days.All chicken free choice feedings and drinking-water.
Testing index：
1st, the 3rd, 6,9 day early morning took a blood sample 1 day before coccidium infection, after coccidium infection, 37 DEG C of standing 2h, 2000rpm centrifugations
20min, separates out serum, -20 DEG C of preservations.Total protein (TP), albumin (ALB), globulin (GLB), paddy in serum are measured respectively
Careless transaminase (AST), glutamic-pyruvic transaminase (ALT), uric acid (UA) concentration；
2nd, survival rate：Survival rate (%)=(chicken number of total chicken number-every group because infecting coccidia death in group) survival i.e. in group
Chicken number/group in total chicken number × 100%；
3rd, bloody stool is scored：The 4-8 days each group chicken excrement bloody stool situations after observation coccidium infection, carry out excrement bloody stool and comment
Point；
Standards of grading are with reference to Suo Xun (1997) score system：To (the same day 8 in given 12h-24h time ranges:00---
Next day 8:00) bloody stool situation is scored, 0 point --- and 100% excrement is without blood；1 point --- the blood stool of 1-25%；2
Point --- the blood stool of 26-50%；3 points --- the blood stool of 51-75%；4 points --- the blood stool of 76-100%；
4th, excrement egg sac number：The 4-8 days each group chicken excrement after collection coccidium infection, according to MeMaster ' s methods, aobvious
Micro- Microscopic observation calculates the egg capsule quantity (oocysts per gram, OPG value) in every gram of excrement；
5th, body weight increase rate：The 9th day early morning to after infecting in the 1st day early morning after attacking driving insect infection, by each group chicken by only empty
Abdomen is weighed；
Body weight increase rate (%)=average weight gain of infected group test chicken/does not infect group (negative control group) experiment of not offeing medicine
Average weight gain × 100% of chicken；
It is as follows that each group measures result：
Influence of the 1 Jia Betel extracts of table to infection coccidia chicken blood biochemical indicator
Note：With column data mark difference lowercase letter indication difference significantly (P<0.05), containing identical lowercase or without word
Matrix shows difference not significantly (P>0.05).Similarly hereinafter.
The 6th day after chicken infects coccidia, compared with control group T2 groups, ALT, AST are dense for experimental group T4 groups, T5 groups, T6 groups
The horizontal obvious reduction of degree, illustrates that Jia Betel extracts can protect liver cell, suppresses the rise of ALT, AST, and can stablize liver cell
Film, suppresses ALT, AST and is released into blood, effectively prevent hepatic injury, mitigates damage of the coccidia to liver.Although Jia Betel extracts are raised
Hello the time is longer than diclazuril, but compares its ALT, AST concentration level, experimental group T4 groups, T5 groups, T6 groups and T3 group differences
Less, and decrease to some degree, although illustrating that Jia Betel extract feeding times are longer, liver is not caused greatly
Damage.Data , Jia Betel extracts with reference to obtained by T2 groups can effectively prevent hepatic injury, mitigate injury of the coccidia to liver,
Feeding will not damage liver for a long time.
Albumin is the depots of histone, for damaged tissue repair, maintains plasma colloid osmotic pressure to stablize, globulin
The immune response of body is primarily involved in, the high low energy of total protein concentration reflects digestion power of the animal to protein to a certain extent
With the height of immunity of organisms.As shown in Table 1, the 9th day after chicken infection coccidia, experimental group T4 groups, T5 groups, T6 groups and control group T1
Group, T2 groups are compared, and the trend substantially risen is presented in total protein, globulin, and albumin also has a degree of rising.With T3 groups
Compare, T4 groups, T5 groups, the total protein of T6 groups, globulin and albumin level are not much different.Illustrate that Jia Betel extracts have
Stronger anti-inflammatory effect, can actively transfer the immune function of body, promote wound healing and body recovery function, its action effect
It is not much different with diclazuril.
The infringement of the increase of uric acid level and kidney trouble, especially renal tubule, the relation being proportionate.In this experiment,
The 9th day after chicken infects coccidia, T3 group uric acid levels are all remarkably higher than other each groups, illustrate that diclazuril has chicken kidney necessarily
The functional lesion side effect of degree.And add Jia Betel extracts experimental group T4, T5, T6 uric acid level and T1 groups without significance difference
It is different, illustrate that Jia Betel extracts are small to kidney injury of chicken, it is without side-effects.
In summary discuss, add the experimental group of Jia Betel extracts, its hepatic injury degree is low, and diseased chicken anti-inflammatory power, be immunized
Function has different degrees of raising, and body function recovers good, its effect is suitable with chemicals diclazuril；And add false
The experimental group of Betel extracts, although feeding time is longer, kidney injury of chicken is still significantly less than the group of feeding diclazuril, long
Time feeding is without side-effects.
2 different tests group of table infection coccidia chicken survival rate (%)
As can be seen from Table 2, experimental group T4 groups, T5 groups and T6 groups can reduce the dead of infection coccidia chicken compared with T2 groups
Die rate, hence it is evident that improve its survival rate, and the death rate and T3 group no significant differences.
3 Jia Betel extracts of table just score and (divide) to infection coccidia chicken blood
As can be seen from Table 3,4-8 days after chicken infection coccidia, experimental group T4 groups, T5 groups, T6 group bloody stool situations compare T2
Group is light, illustrates that Jia Betel extracts have certain effect to mitigating chickens infected with eimeria symptom, illustrates that Jia Betel extracts can mitigate
The degree of chickens infected with eimeria.
4 Jia Betel extracts of table are to infecting the influences (a/gram) of coccidia chicken manure OPG values
As can be seen from Table 4, coccidian oocyst is not observed in negative control group chicken manure.The 4-8 days after coccidia is infected,
Experimental group T4 groups, T5 groups, T6 group chicken manure OPG values are substantially less than T2 groups.The 6th day after infection, experimental group chicken manure OPG values
Reach highest, start gradually to reduce after the 7th day.Illustrate that Jia Betel extracts have certain killing effect for Eimeria species, and
With the increase that the Jia Betel extract times are added in feed, coccidia killing effect is gradually strengthened.
The change of weight before and after each test group chicken infection coccidia of table 5
As shown in Table 2, control group T2 body weight increase rates are worst, compared with control group T1, significantly reduce (P ＜ 0.05)；T3-
T6 groups are compared with control group T1, although body weight increase rate has declined, remain above control group T2 groups, and experimental group T4
Group, T5 groups, T6 groups body weight increase rate and no significant difference compared with T3 groups, although illustrating vacation Betel extract feeding times compared with ground
Gram pearl profit group leader, but chicken weight gain situation is not much different.Therefore , Jia Betel extracts can raise for a long time as feed addictive
Hello, play the role of preventing coccidia.
In addition, being found in experimentation, infect after coccidia the 3rd day, in addition to T1 groups, other each groups the state of mind occur not
It is good, drowsiness, the symptoms such as happiness flocks together；4th day, a small amount of bloody stool, chicken feed intake can be seen into T6 group excrement by infecting the T2 of coccidia
Reduce；The 5-6 days, bloody stool amount showed increased in excrement, T2 group most serious；The 7-8 days, T3 groups to T6 groups, bloody stool amount in excrement
Gradually reduce, the chicken state of mind is gradually recovered.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on, should all be included in the protection scope of the present invention god.
Claims (5)
1. a kind of application of Jia Betel extracts on the preparation for preparing prevention global-worm illness, the preparation method of the Jia Betel extracts are adopted
With supercritical carbon dioxide extraction method, extraction conditions are：It is 20-40 mesh that Jia Betel cauline leafs, which are crushed to granularity, extracting pressure 15-
40MPa, extraction temperature are 35-60 DEG C, carbon dioxide flow 40-60L/h, extraction time 1.0-3h.
2. the application of Jia Betel extractions extract according to claim 1, it is characterised in that：The Jia Betel extracts are used for
Prepare the preparation of prevention coccidiosis of domestic fowls.
3. the application of Jia Betel extractions extract according to claim 2, it is characterised in that：The poultry is chicken.
4. a kind of application of Jia Betel extract formulations on the feed for preparing prevention global-worm illness, the preparation side of the Jia Betel extracts
Method uses supercritical carbon dioxide extraction method, and extraction conditions are：It is 20-40 mesh that Jia Betel cauline leafs, which are crushed to granularity, and extracting pressure is
15-40MPa, extraction temperature are 35-60 DEG C, carbon dioxide flow 40-60L/h, extraction time 1.0-3h.
5. the application of Jia Betel extract formulations according to claim 4, it is characterised in that：The Jia Betel extract formulations
Additive amount in feed is 200-600mg/kg.
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| CN105767129B (en) * | 2016-03-17 | 2020-07-28 | 广东海洋大学 | Piper sarmentosum roxb leaf extract and application thereof in fresh keeping of pitaya |
| CN105942290A (en) * | 2016-05-27 | 2016-09-21 | 岭南师范学院 | Piper sarmentosum health-care red snapper ball and preparation method thereof |
| CN107259190A (en) * | 2017-07-27 | 2017-10-20 | 广西南宁乐蕊生物科技有限责任公司 | A kind of chicken feed addictive |
| CN107347991B (en) * | 2017-07-31 | 2020-05-12 | 广西南宁市宾阳县聚丰米业有限公司 | Method for preventing storage pests in granary |
| CN113068767A (en) * | 2021-03-30 | 2021-07-06 | 中国热带农业科学院热带生物技术研究所 | Application of sarmentosum bungei extract in preparation of additive for preventing and treating avian aspergillosis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102038007A (en) * | 2009-10-09 | 2011-05-04 | 中国热带农业科学院环境与植物保护研究所 | Sarmentose pepper herb extract and application thereof in preparing insecticidal bacteriostat |
| CN104605195A (en) * | 2015-01-20 | 2015-05-13 | 中国热带农业科学院热带作物品种资源研究所 | Additive for feed for weaned pigs as well as preparation method and application of additive |
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| KR101106056B1 (en) * | 2011-02-21 | 2012-01-18 | 건국대학교 산학협력단 | Antimicrobial composition for pathogenic microorganism comprising plant or extract thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102038007A (en) * | 2009-10-09 | 2011-05-04 | 中国热带农业科学院环境与植物保护研究所 | Sarmentose pepper herb extract and application thereof in preparing insecticidal bacteriostat |
| CN104605195A (en) * | 2015-01-20 | 2015-05-13 | 中国热带农业科学院热带作物品种资源研究所 | Additive for feed for weaned pigs as well as preparation method and application of additive |
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