CN104606462A - Medicine for conditioning alcoholic fatty liver and preparation method of medicine - Google Patents
Medicine for conditioning alcoholic fatty liver and preparation method of medicine Download PDFInfo
- Publication number
- CN104606462A CN104606462A CN201510061461.4A CN201510061461A CN104606462A CN 104606462 A CN104606462 A CN 104606462A CN 201510061461 A CN201510061461 A CN 201510061461A CN 104606462 A CN104606462 A CN 104606462A
- Authority
- CN
- China
- Prior art keywords
- minutes
- parts
- minute
- fatty liver
- alcoholic fatty
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for conditioning an alcoholic fatty liver. The medicine is mainly prepared from the following raw materials in parts by weight: 10-20 parts of loranthus parasiticus, 15-30 parts of puerarin, 3-6 parts of flos daturae, 6-9 parts of pulsatilla chinensis regel, 4-8 parts of Japanese polygala, 10-15 parts of rhizoma corydalis (processed with vinegar), 6-9 parts of motherwort fruit, 10-20 parts of semen arecae, 10-20 parts of salviae miltiorrhizae, 8-12 parts of orange peel, 6-9 parts of flos carthami, 9-15 parts of rhizoma alismatis, 8-12 parts of polyporus umbellatus and 10-15 parts of anemarrhenae. The medicinal materials are reasonably matched according to the principle of the traditional Chinese medicine, so that the medicine has the efficacies of tonifying the spleen to raise liver, activating blood and easing pain, and is high in recovery rate and significant in curative effect on the alcoholic fatty liver.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to medicament and the preparation of conditioning alcoholic fatty liver.
Background technology
Alcoholic fatty liver is the hepatic disease because long-term heavy drinking causes.Alcoholic hepatitis premorbid often has heavy drinking history in a short time, patient have significantly lose weight, inappetence, nausea and vomiting, malaise, the symptoms such as abdominal pain diarrhea.According to statistics, have the patient of 77% to occur inappetence, 55% have nausea and vomiting, 46% have stomachache, losing weight appears in the patient of 43%.Jaundice, hepatomegaly and tenderness are the common signs of alcoholic hepatitis patient.Have the patient of 81% to occur hepatomegaly, the patient of 77% has jaundice.Transaminase's moderate increases.The clinical manifestation of alcoholic fatty liver is directly proportional to the degree of fatty infiltration of liver, in liver excess fat be removed after symptom can disappear.Being most common signs with hepatomegaly clinically, is secondly pain in the hepatic region and tenderness.A few patients can have slight jaundice, and lab testing prompting is blocked relevant with biliary system.Patient with severe symptoms can have ascites and lower limbs edema, accidental splenomegaly.Some patients can show with vitamin deficiency, as peripheral neuritis, glossitis, angular cheilitis, the dermal ecchymosis etc.In a word, alcoholic fatty liver lacks specific clinical symptoms.
Publication No. CN 103083573 A(application number 201310043267.4) Chinese patent literature disclose a kind of Chinese medicine for the treatment of alcoholic fatty liver, this Chinese medicine composition is by Herba Swertiae Puniceae, Herba Meliloti Suaveolentis, Radix Oenotherae erythrosepalae, Fructus Akebiae, marigold flower, Stigma Maydis, Rhizoma Polygoni Cuspidati, Pericarpium Citri Reticulatae Viride, Cynara scolymus L (Cyhara cardunculus.), Herba Camptosori Sibirici, Endoconcha Sepiae is made.Publication No. CN 103536851 A(application number 201310500883.8) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of alcoholic fatty liver, this Chinese medicine composition is made up of Radix Salviae Miltiorrhizae, Herba Lysimachiae, Radix Curcumae, Fructus Corni, Herba Taraxaci, Herba Artemisiae Scopariae, Fructus Crataegi, Fructus Forsythiae, Radix Semiaquilegiae, Herba Equiseti Hiemalis, Radix Bupleuri, Radix Scutellariae, Fructus Aurantii Immaturus, Radix Et Rhizoma Rhei.Publication No. CN 102688451 A(application number 201210182718.8) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of alcoholic fatty liver, this Chinese medicine composition is made up of Herba Cistanches, Herba Lycopi, Radix Curcumae, Fructus Corni, Rhizoma Curcumae Longae, Pericarpium Citri Reticulatae Viride, Fructus Crataegi, Radix Semiaquilegiae, Herba Equiseti Hiemalis, Radix Puerariae, Rhizoma Acori Graminei, Thallus Laminariae (Thallus Eckloniae), Radix Gentianae Macrophyllae, Folium Ginkgo, Spica Prunellae.
In modern medicine, mainly take to keep on a diet, alleviating alcohol addiction and the mode strengthening taking exercise alleviate this disease, there is no the effective means of safe and effective treatment alcoholic fatty liver, the therapeutic effect of some chemicalses needs to verify further, therefore Chinese traditional treatment has more advantage, therefore should strengthen the formulating to this disease.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take medicament and the preparation of the wide conditioning alcoholic fatty liver of safe and applicable.
Technical scheme of the present invention is:
The medicament of conditioning alcoholic fatty liver, is prepared from primarily of following bulk drugs, is weight portion: Herba Taxilli 10-20; Radix Puerariae 15-30; Flos Daturae 3-6; Radix Pulsatillae 6-9; Herba Polygalae Japonicae 4-8; Rhizoma Corydalis (vinegar system) 10-15; Fructus Leonuri 6-9; Bin youth 10-20; Radix Salviae Miltiorrhizae 10-20; Pericarpium Citri tangerinae 8-12; Flos Carthami 6-9; Rhizoma Alismatis 9-15; Polyporus 8-12; Rhizoma Anemarrhenae 10-15.
Preferably, Herba Taxilli 12-18; Radix Puerariae 20-25; Flos Daturae 4-5; Radix Pulsatillae 7-8; Herba Polygalae Japonicae 5-7; Rhizoma Corydalis (vinegar system) 11-14; Fructus Leonuri 7-8; Bin youth 12-18; Radix Salviae Miltiorrhizae 12-18; Pericarpium Citri tangerinae 9-11; Flos Carthami 7-8; Rhizoma Alismatis 11-13; Polyporus 9-11; Rhizoma Anemarrhenae 11-14.
More preferably, Herba Taxilli 15; Radix Puerariae 22.5; Flos Daturae 4.5; The Radix Pulsatillae 7.5; Herba Polygalae Japonicae 6; Rhizoma Corydalis (vinegar system) 12.5; Fructus Leonuri 7.5; Bin youth 15; Radix Salviae Miltiorrhizae 15; Pericarpium Citri tangerinae 10; Flos Carthami 7.5; Rhizoma Alismatis 12; Polyporus 10; The Rhizoma Anemarrhenae 12.5.
The medicament of described conditioning alcoholic fatty liver, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize together with step (1) (2) made crude drug, loads in bag filter;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, then step (3) gained bag filter is put into marmite, turn little fire and decoct 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filter to get filtrate, collect filtering residue;
(5) by step (4) gained filtering residue, add water and continue decoction 25 minutes, filtered while hot obtains filtrate, mixes twice gained filtrate, obtains decoction.
The preparation method of the medicament decoction of described conditioning alcoholic fatty liver, step (4) amount of water is that the 6-8 of total raw material medicine weight is doubly (preferred: amount of water is 6.5-7.5 times of total raw material medicine weight; Be more preferably: amount of water is 7 times of total raw material medicine weight).
The medicament of described conditioning alcoholic fatty liver, be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize, obtain medicated powder together with step (1) (2) made crude drug;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add water and do not have crude drug 3cm to soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turns little fire and decocts 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filtered while hot, collects filtrate;
(5) by step (4) gained filtrate reduced in volume to thick paste, add step (3) gained medicated powder and adjuvant Icing Sugar, dry after pulverize make granule, obtain electuary.
The preparation method of the medicament electuary of described conditioning alcoholic fatty liver, the amount of step (5) adjuvant is the 0.2-0.4 of thick paste weight doubly (preferred: the amount of adjuvant is 0.3 times of thick paste weight).
The medicament of described conditioning alcoholic fatty liver, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add crude drug gross weight 6-9 water doubly (preferably: add crude drug gross weight 7-8 water doubly; Be more preferably: the water adding crude drug gross weight 7.5 times) soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turn little fire and decoct 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filtered while hot, collects filtrate, this filtrate of spraying dry;
(4) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, run through rear shredding, dry, made crude drug is pulverized together with dry thing with step (1) (2) (3), obtains powder.
The preparation method of the medicament powder of described conditioning alcoholic fatty liver, pulverized 120-180 mesh sieve (preferred: to pulverize 140-160 mesh sieve in step (4); Be more preferably: pulverized 150 mesh sieves).
The medicament of described conditioning alcoholic fatty liver, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize, obtain medicated powder together with step (1) (2) made crude drug;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add water and do not have crude drug 3cm to soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turns little fire and decocts 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filtered while hot, collects filtrate;
(5) by step (4) gained filtrate reduced in volume to thick paste, add step (3) gained medicated powder, stir, obtain unguentum.
The preparation method of the medicament unguentum of described conditioning alcoholic fatty liver, step is evaporated to relative density 1.22-1.28(55 DEG C in (5)) thick paste (preferred: the thick paste being evaporated to relative density 1.24-1.26; Be more preferably: be evaporated to the thick paste that relative density is 1.25).
The reagent combination science of conditioning alcoholic fatty liver provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, the present invention is according to Chinese traditional medicine principle reasonably combined medical material, has spleen reinforcing nourishing the liver, the effect of analgesic therapy of invigorating blood circulation;
2, the various dosage form of this prescription gained, all to human non-toxic's side effect, safe and effective, and therapeutic effect is good;
3, products obtained therefrom of the present invention both can improve liver function, alleviated uncomfortable disease, can also strengthen body immunity.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the medicament of conditioning alcoholic fatty liver, is prepared from primarily of following bulk drugs, every part of 4g: Herba Taxilli 10 parts, Radix Puerariae 15 parts, Flos Daturae 3 parts, the Radix Pulsatillae 6 parts, Herba Polygalae Japonicae 4 parts, Rhizoma Corydalis (vinegar system) 10 parts, Fructus Leonuri 6 parts, Bin youth 10 parts, Radix Salviae Miltiorrhizae 10 parts, Pericarpium Citri tangerinae 8 parts, 6 parts, Flos Carthami, Rhizoma Alismatis 9 parts, Polyporus 8 parts, the Rhizoma Anemarrhenae 10 parts.The preparation method of the medicament decoction of above-mentioned conditioning alcoholic fatty liver is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 20 minutes, take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, the rice vinegar with 10% sprays profit, cuts sheet, be placed in parch container after sealing vexed 15 minutes, and slow fire heats, and fry to micro-yellow, taking-up is dried in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize together with step (1) (2) made crude drug, loads in bag filter;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add the water soaking 10 minutes of total raw material medicine weight 7 times, after moderate heat is boiled, constantly boiling 15 minutes, again step (3) gained bag filter is put into marmite, turn little fire to decoct 35 minutes, filter to get filtrate, collect filtering residue;
(5) by step (4) gained filtering residue, add water and continue decoction 25 minutes, filtered while hot obtains filtrate, mixes twice gained filtrate, obtains decoction.
embodiment 2the medicament of conditioning alcoholic fatty liver, is prepared from primarily of following bulk drugs, every part of 4g: Herba Taxilli 20 parts, Radix Puerariae 30 parts, Flos Daturae 6 parts, the Radix Pulsatillae 9 parts, Herba Polygalae Japonicae 8 parts, Rhizoma Corydalis (vinegar system) 15 parts, Fructus Leonuri 9 parts, Bin youth 20 parts, Radix Salviae Miltiorrhizae 20 parts, Pericarpium Citri tangerinae 12 parts, 9 parts, Flos Carthami, Rhizoma Alismatis 15 parts, Polyporus 12 parts, the Rhizoma Anemarrhenae 15 parts.The preparation method of the medicament electuary of above-mentioned conditioning alcoholic fatty liver is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 20 minutes, take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, the rice vinegar with 10% sprays profit, cuts sheet, be placed in parch container after sealing vexed 15 minutes, and slow fire heats, and fry to micro-yellow, taking-up is dried in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize, obtain medicated powder together with step (1) (2) made crude drug;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add water and do not have crude drug 3cm to soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turns little fire and decocts 35 minutes, filtered while hot, collects filtrate;
(5) by step (4) gained filtrate reduced in volume to thick paste, add the adjuvant Icing Sugar of step (3) gained medicated powder and thick paste weight 0.3 times, dry after pulverize make granule, obtain electuary.
Model case: xxx, male, 46 years old.Medical history: patient's obese, smokes and drink for a long time, and because liver's regional pain is gone to a doctor, have a medical check-up display of blood pressure 155/95mmHg, Body Mass Index is about 28, and the traditional Chinese medical science is had a medical check-up as body of the tongue is comparatively dark, white and greasy fur, stringy and rolling pulse, finds liver function mile abnormality on inspection, is finally diagnosed as alcoholic fatty liver.
Under the suggestion of doctor, alleviating alcohol addiction, reinforcement are taken exercise and take this example gained medicament electuary, each 2-4g, warm boiled water, one day twice 15 days is a course for the treatment of, after patient takes a course for the treatment of, body weight alleviates to some extent, and blood pressure drops is to 125/80mmHg, continue to take a course for the treatment of, liver function is recovered gradually, and after consolidating again 15 days, the state of an illness is fully recovered, through examination in hospital, indices is without exception.
embodiment 3the medicament of conditioning alcoholic fatty liver, is prepared from primarily of following bulk drugs, every part of 4g: Herba Taxilli 12 parts, Radix Puerariae 20 parts, Flos Daturae 4 parts, the Radix Pulsatillae 7 parts, Herba Polygalae Japonicae 5 parts, Rhizoma Corydalis (vinegar system) 11 parts, Fructus Leonuri 7 parts, Bin youth 12 parts, Radix Salviae Miltiorrhizae 12 parts, Pericarpium Citri tangerinae 9 parts, 7 parts, Flos Carthami, Rhizoma Alismatis 11 parts, Polyporus 9 parts, the Rhizoma Anemarrhenae 11 parts.The preparation method of the medicament powder of above-mentioned conditioning alcoholic fatty liver is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 20 minutes, take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, the rice vinegar with 10% sprays profit, cuts sheet, be placed in parch container after sealing vexed 15 minutes, and slow fire heats, and fry to micro-yellow, taking-up is dried in the air cool;
(3) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add the water soaking 10 minutes of crude drug gross weight 7.5 times, after moderate heat is boiled, constantly boiling 15 minutes, turn little fire to decoct 35 minutes, filtered while hot, collects filtrate, this filtrate of spraying dry;
(4) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, run through rear shredding, dry, made crude drug pulverized 150 mesh sieves together with dry thing with step (1) (2) (3), obtained powder.
Model case: xxx, women, 34 years old.Medical history: patient is salesman, because of job demand, every day, drinking amount was more than 75ml, in the recent period because overtime work is continuously stayed up late, the symptom such as occur heating, whole body profuse sweating, hepatic region swell and ache, removes hospital admission, check and find that serum transaminase raises, hepatosplenomegaly, B ultrasonic is shown as moderate alcoholic fatty liver.
Take this example gained medicament powder, each 2-4g, warm boiled water, one day twice, within 15 days, be a course for the treatment of, patient takes two courses for the treatment of, uncomfortable disease is substantially all eliminated, and health and spirit are clearly better, and adhere to again taking a course for the treatment of, return examination in hospital, indices is all normal, and liver function recovery, after drug withdrawal, patient strengthens taking exercise and rational diet, follows up a case by regular visits in 1 year and does not recur.
embodiment 4the medicament of conditioning alcoholic fatty liver, is prepared from primarily of following bulk drugs, every part of 4g: Herba Taxilli 18 parts, Radix Puerariae 25 parts, Flos Daturae 5 parts, the Radix Pulsatillae 8 parts, Herba Polygalae Japonicae 7 parts, Rhizoma Corydalis (vinegar system) 14 parts, Fructus Leonuri 8 parts, Bin youth 18 parts, Radix Salviae Miltiorrhizae 18 parts, Pericarpium Citri tangerinae 11 parts, 8 parts, Flos Carthami, Rhizoma Alismatis 13 parts, Polyporus 11 parts, the Rhizoma Anemarrhenae 14 parts.The preparation method of the medicament unguentum of above-mentioned conditioning alcoholic fatty liver is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 20 minutes, take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, the rice vinegar with 10% sprays profit, cuts sheet, be placed in parch container after sealing vexed 15 minutes, and slow fire heats, and fry to micro-yellow, taking-up is dried in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize, obtain medicated powder together with step (1) (2) made crude drug;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add water and do not have crude drug 3cm to soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turns little fire and decocts 35 minutes, filtered while hot, collects filtrate;
(5) be 1.25(55 DEG C by step (4) gained filtrate reduced in volume to relative density) thick paste, add step (3) gained medicated powder, stir, obtain unguentum.
Model case: xxx, male, 55 years old.Main suit: patient is government staff, because long-term alcohol is excessive, and infrequently take exercise, find during health check-up and suffer from slight alcoholic fatty liver, start subsequently to keep on a diet and alleviating alcohol addiction, after the state of an illness is alleviated to some extent, just do not note again, occur liver pain in the recent period, the malaise symptoms such as inappetence, through examination in hospital, alcoholic fatty liver is by slightly transferring moderate to.
Under the suggestion of layman, take Chinese medicine conditioning, take this example gained medicament thick paste, each 3-5g, warm boiled water, one day twice, within 15 days, be a course for the treatment of, after patient takes a course for the treatment of, uncomfortable disease obviously alleviates, pain relief, adheres to again taking two weeks, and alcoholic fatty liver starts to recover normal, after consolidating a course for the treatment of, liver function recovery, after drug withdrawal, control is drunk, and does not recur in 1 year.
embodiment 5the medicament of conditioning alcoholic fatty liver, is prepared from primarily of following bulk drugs, every part of 4g: Herba Taxilli 15 parts, Radix Puerariae 22.5 parts, Flos Daturae 4.5 parts, the Radix Pulsatillae 7.5 parts, Herba Polygalae Japonicae 6 parts, Rhizoma Corydalis (vinegar system) 12.5 parts, Fructus Leonuri 7.5 parts, Bin youth 15 parts, Radix Salviae Miltiorrhizae 15 parts, Pericarpium Citri tangerinae 10 parts, 7.5 parts, Flos Carthami, Rhizoma Alismatis 12 parts, Polyporus 10 parts, the Rhizoma Anemarrhenae 12.5 parts.The preparation method of the medicament decoction of above-mentioned conditioning alcoholic fatty liver is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 20 minutes, take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, the rice vinegar with 10% sprays profit, cuts sheet, be placed in parch container after sealing vexed 15 minutes, and slow fire heats, and fry to micro-yellow, taking-up is dried in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize together with step (1) (2) made crude drug, loads in bag filter;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add the water soaking 10 minutes of total raw material medicine weight 7 times, after moderate heat is boiled, constantly boiling 15 minutes, again step (3) gained bag filter is put into marmite, turn little fire to decoct 35 minutes, filter to get filtrate, collect filtering residue;
(5) by step (4) gained filtering residue, add water and continue decoction 25 minutes, filtered while hot obtains filtrate, mixes twice gained filtrate, obtains decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Taxilli: base is former: be the branch and leaf of Loranthaceae plant Herba Visci, Herba Taxilli or loranthus yadoriki etc.Chemical analysis: Herba Visci stem, leaf are containing oleanolic acid, and β-Amyrin, meso inositol, flavone compound, still isolates Lupeol, cupreol and a flavonoid glycoside.Nature and flavor: bitter sweet are flat.Gui Jing: enter liver, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, and the meridian dredging, beneficial blood, antiabortive.Control soreness of waist and knee joint, muscles and bones flaccidity is weak, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.
Radix Puerariae: nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Cure mainly: for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Flos Daturae: base is former: be the dried floral of plant of Solanaceae datura metel or datura innoxia.Chemical analysis: datura metel plant (other Datura plants too) each several part all contains alkaloid, but leads as the highest with Hua Zhonghan, reaches 0.43%.Based on hyoscine in alkaloid, hyoscyamine takes second place (in leaf alkaloid containing rate primary and secondary just with spend in contrary).Nature and flavor: pungent, temperature, poisonous.Gui Jing: return lung; Liver Channel.Function cures mainly: smooth-going cough-relieving; Narcotic analgesic; Spasmolytic is only jerked.Main asthma and cough; Gastral cavity abdomen is cold educates; Rheumatic arthralgia; Epilepsy; Infantile convulsion; Surgical anesthesia.
The Radix Pulsatillae: base is former: be the root of the ranunculaceae plant Radix Pulsatillae.Nature and flavor with return through: bitter, cold.Return stomach, large intestine channel.Function with cure mainly: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.For toxic-heat and blood stasis, pudendal pruritus leukorrhagia.
Herba Polygalae Japonicae: base is former: be herb or the root of milk wort Herba Polygalae Japonicae.Chemical analysis: root is containing triterpenoid saponin, resin, fatty oil, polygalytol.Nature and flavor: bitter in the mouth; Micro-pungent; Property is put down.Gui Jing: lung; Stomach; Heart channel.Expelling phlegm for arresting cough; Dissipating blood stasis stops blooding; Mind tranquilizing and the heart calming; Removing toxic substances and promoting subsidence of swelling.Main cough with copious phlegm; Traumatic injury, rheumatic arthralgia; Spit blood; Have blood in stool; Cardiopalmus; Insomnia; Laryngopharynx swelling and pain; Carbuncle skin infection; Venom.
Rhizoma Corydalis: base is former: be the tuber of papaveraceae plant corydalis.Nature and flavor: arduous, temperature.Gui Jing: enter liver, stomach warp.Function cures mainly: invigorate blood circulation, and dissipating blood stasis is regulated the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
Fructus Leonuri: base is former: be the fruit of Labiatae mother wort plant Herba Leonuri and Herba Leonuri Sibirici.Composition: leonuri,fructus is containing alkaloid: leonurinine alkali, stachydrine, fatty oil, in oil, main component is oleic acid etc.Herb is containing phenolic glycoside class: A, B; Flavonoid glycoside: rutin, isoquercitrin, silver linden glycoside isorhamnetin-3-O-rutinoside.Iridoid glycosides.Herba Leonuri Sibirici fruit kind oil is containing allene class fatty acid: 7,8-eicosadienoic acid.The property of medicine: sweet, pungent, is slightly cold, mild toxicity.Return Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.Cure mainly menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal; Liver-heat is had a headache, dizzy, conjunctival congestion and swelling pain, the raw cataracta of order.
Bin youth: base is former: be the seed of babassu Semen Arecae.Chemical analysis: Semen Arecae contains alkaloid 0.3 ~ 0.6%, condensed tannin 15%, fat 14% and areca red.Alkaloid master is arecoline, content 0.1 ~ 0.5%; All the other have arecaidine, demethyl arecaidine, guvacoline, arecolidine, homarecoline etc.It is high that raw areca contains biological alkali number than goods.Nature and flavor: toil, temperature.Gui Jing: enter spleen, stomach, large intestine channel.Function cures mainly: parasite killing, removing mass, the therapeutic method to keep the adverse QI flowing downwards, row water.Control malnutrition due to parasitic infestation, dyspepsia, abdominal distention, heavy after dysentery, malaria, edema, beriberi, accumulation of phlegm in the hypochondrium, crux.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, cold nature.Energy blood circulation promoting and blood stasis dispelling, removing heat from blood, calms the nerves.Enter the heart, spleen two warp.According to " book on Chinese herbal medicine is looked for the truth ": Radix Salviae Miltiorrhizae has the effect into percardium removing blood stasis with potent drugs.Modern medicine study confirms, its energy coronary artery dilator, increases coronary flow, improve myocardial ischemia, infraction and cardiac function, regulate the rhythm of the heart, and can expand peripheral blood vessel, improve microcirculation; Body's hypoxia tolerance can be improved; There is anticoagulation, promote fibrinolytic, suppress platelet aggregation, the effect of inhibition thrombosis; Can blood fat be reduced, suppress coronary atherosclerosis to be formed; The convalescent period of erythrocyte and hematochrome can be shortened, Reticulocyte is increased, the reparation organized can be promoted, accelerate the healing of fracture; Nervus centralis is had to have inhibitory action; There is antitumor action; Energy enhancing human body immunity function; Blood glucose can be reduced; Inhibitory action is had to various bacteria such as tubercule bacillus.
Pericarpium Citri tangerinae: base is former: be the peel of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae.After October, harvesting ripe fruit, strips peel, dries in the shade or dries.Chemical analysis: tangerine produced in fujian province peel, containing volatile oil, is wherein mainly limonene.Nature and flavor: arduous, temperature.Gui Jing: enter spleen, lung meridian.Function cures mainly: regulate the flow of vital energy, and in tune, dampness, reduces phlegm.Control distension and fullness of the chest and abdomen, anorexia, vomiting hiccup, cough with copious phlegm.Also fish, Eriocheir sinensis poison is separated.
Flos Carthami: base is former: Compositae, Flos Carthami platymiscium, dry tubular flower, orange red.Chemical composition: containing carthamone, neocarthamin, saffloside, Carthamus yellow and flavochrome.Another containing safflower oil, oil comprises Palmic acid, myristic acid, lauric acid, stearic acid, arachidic acid, oleic acid etc.Pharmacological action: the effect having slight excited heart, reduce coronary resistance, increase coronary flow and cardiac muscle nutritional blood flow; Protect and improve myocardial ischemia, reducing myocardial infarct size; Reddish yellow pigment separator can to arrhythmia; Decoct, Aqueous extracts, Carthamus yellow etc. can be expanded peripheral vessels, reduce blood pressure.Energy anticoagulant, fortifying fibre protein dissolution, reduces whole blood viscosity.Injection, ethanol extract, saffloside can significantly improve hypoxia-bearing capability, have protective effect to the weary oxygen encephalopathy of ischemia.Nature and flavor with return through: pungent, temperature.GUIXIN, Liver Channel.There is effect of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.For controlling amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Rhizoma Alismatis: nature and flavor with return through: sweet, light, cold.Return kidney, urinary bladder channel.There is promoting diuresis to eliminate damp pathogen, expel the heat-evil, change effect of turbid blood fat reducing.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipemia.
Polyporus: base is former: be the dry sclerotia of Polyporaceae plant Polyporus.Chemical analysis: containing ergosterol, biotin, saccharide, protein.Nature and flavor: sweet light are flat.Gui Jing: enter spleen, kidney, urinary bladder channel.Function cures mainly: diuresis eliminating dampness by diuresis.Control dysuria, edema distension, beriberi, has loose bowels, drench, turbid, leukorrhagia.
The Rhizoma Anemarrhenae: nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
test example 1the clinical practice of the medicament (embodiment 5) of gained conditioning alcoholic fatty liver of the present invention:
Choose crowd: according to hospital admission record, screening is diagnosed as patient 379 example of alcoholic fatty liver, wherein women 185 example, male 194 example, the range of age 35-65 year, 48.6 years old mean age, the course of disease is the shortest is half a year.Diagnostic criteria 1. has long-term alcohol history, generally more than 5 years, amounts to amount of alcohol >=40g/d, women >=20g/d; Or in 2 weeks, have heavy drinking history (>80g/d).2. after alcohol prohibition, serum alanine aminotransferase (ALT), aspartate amino transferase (AST) and gamma glutamyl transpeptidase (GGT) obviously decline, in 4 weeks, basic recovery is normal, namely below 2 times of upper limits of normal values.The liver of enlargement obviously reduces in 1 week, within 4 weeks, substantially recovers normal.3. should note whether merging HBV or HCV infection during diagnosis, except the hepatic injury that causes such as Developmental and Metabolic Disorder and medicine.
Before test, patient is divided into two groups at random, experimental group 244 example and matched group 135 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes gained decoction of the present invention, each 40-60ml, one day twice, warmly takes, and within 15 days, is a course for the treatment of; Matched group takes other conventional medicines (liver-protecting tablet, glucurolactone, glycyrrhizic acid preparation, ursodesoxycholic acid, vitamin E etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptoms and sign disappear, and blood fat and liver function recovery normally, do not recur in 1 year; (2) effective: clinical symptoms and sign are obviously improved, and liver function is recovered to some extent, occasionally there is recurrence; (3) invalid: clinical symptoms and sign are improved not obvious, liver function is front without significant change with treatment.
Clinical effectiveness: after the taking medicine of four courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
Therapeutic effect: as can be seen from Table 1, the cure rate taking gained medicine of the present invention can reach 64.3%, total effective rate is 97.5%, and the cure rate taking other drug is only 43.7%, total effective rate is 79.3%, and inefficiency is up to 20.7%, it can thus be appreciated that the pharmaceutical treatment Be very effective of gained of the present invention conditioning alcoholic fatty liver is higher than other drug.
The Chinese medicine used in the present invention, there is the Herba Taxilli of the liver and the kidney tonifying, the Radix Puerariae of expelling pathogenic factors from muscles for reducing heat, the Flos Daturae of smooth-going cough-relieving, the Radix Pulsatillae of heat-clearing and toxic substances removing, the Herba Polygalae Japonicae of mind tranquilizing and the heart calming, the Rhizoma Corydalis of blood circulation promoting regulates qi, the Fructus Leonuri of liver heat removing and eyesight improving, the Semen Arecae of therapeutic method to keep the adverse QI flowing downwards row water, the Radix Salviae Miltiorrhizae of blood circulation promoting and blood stasis dispelling, the Pericarpium Citri tangerinae of regulating the flow of vital energy in adjusting, the Flos Carthami of promoting blood circulation to restore menstrual flow, change the Rhizoma Alismatis of turbid blood fat reducing, the Polyporus of diuresis eliminating dampness by diuresis, the nourshing Yin and drynsessmoistening prescription Rhizoma Anemarrhenae, all medicines share, play drug effect altogether, can the effective alleviation of alcohol fatty liver uncomfortable disease of bringing, regulate liver function, strengthen patient body immunity.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. nurse one's health the medicament of alcoholic fatty liver, it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Herba Taxilli 10-20; Radix Puerariae 15-30; Flos Daturae 3-6; Radix Pulsatillae 6-9; Herba Polygalae Japonicae 4-8; Rhizoma Corydalis (vinegar system) 10-15; Fructus Leonuri 6-9; Bin youth 10-20; Radix Salviae Miltiorrhizae 10-20; Pericarpium Citri tangerinae 8-12; Flos Carthami 6-9; Rhizoma Alismatis 9-15; Polyporus 8-12; Rhizoma Anemarrhenae 10-15.
2. the medicament of conditioning alcoholic fatty liver as claimed in claim 1, is characterized in that, Herba Taxilli 12-18; Radix Puerariae 20-25; Flos Daturae 4-5; Radix Pulsatillae 7-8; Herba Polygalae Japonicae 5-7; Rhizoma Corydalis (vinegar system) 11-14; Fructus Leonuri 7-8; Bin youth 12-18; Radix Salviae Miltiorrhizae 12-18; Pericarpium Citri tangerinae 9-11; Flos Carthami 7-8; Rhizoma Alismatis 11-13; Polyporus 9-11; Rhizoma Anemarrhenae 11-14(is preferably: Herba Taxilli 15; Radix Puerariae 22.5; Flos Daturae 4.5; The Radix Pulsatillae 7.5; Herba Polygalae Japonicae 6; Rhizoma Corydalis (vinegar system) 12.5; Fructus Leonuri 7.5; Bin youth 15; Radix Salviae Miltiorrhizae 15; Pericarpium Citri tangerinae 10; Flos Carthami 7.5; Rhizoma Alismatis 12; Polyporus 10; The Rhizoma Anemarrhenae 12.5.
3. the medicament of the conditioning alcoholic fatty liver as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize together with step (1) (2) made crude drug, loads in bag filter;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, then step (3) gained bag filter is put into marmite, turn little fire and decoct 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filter to get filtrate, collect filtering residue;
(5) by step (4) gained filtering residue, add water and continue decoction 25 minutes, filtered while hot obtains filtrate, mixes twice gained filtrate, obtains decoction.
4. the preparation method of the medicament decoction of conditioning alcoholic fatty liver as claimed in claim 3, is characterized in that, step (4) amount of water is that the 6-8 of total raw material medicine weight is doubly (preferred: amount of water is 6.5-7.5 times of total raw material medicine weight; Be more preferably: amount of water is 7 times of total raw material medicine weight).
5. the medicament of the conditioning alcoholic fatty liver as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize, obtain medicated powder together with step (1) (2) made crude drug;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add water and do not have medical material 3cm to soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turns little fire and decocts 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filtered while hot, collects filtrate;
(5) by step (4) gained filtrate reduced in volume to thick paste, add step (3) gained medicated powder and adjuvant Icing Sugar, dry after pulverize make granule, obtain electuary.
6. the preparation method of the medicament electuary of conditioning alcoholic fatty liver as claimed in claim 5, is characterized in that, the amount of step (5) adjuvant is the 0.2-0.4 of thick paste weight doubly (preferred: the amount of adjuvant is 0.3 times of thick paste weight).
7. the medicament of the conditioning alcoholic fatty liver as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add crude drug gross weight 6-9 water doubly (preferably: add crude drug gross weight 7-8 water doubly; Be more preferably: the water adding crude drug gross weight 7.5 times) soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turn little fire and decoct 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filtered while hot, collects filtrate, this filtrate of spraying dry;
(4) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, run through rear shredding, dry, made crude drug is pulverized together with dry thing with step (1) (2) (3), obtains powder.
8. the preparation method of the medicament powder of conditioning alcoholic fatty liver as claimed in claim 7, is characterized in that, pulverized 120-180 mesh sieve (preferred: to pulverize 140-160 mesh sieve in step (4); Be more preferably: pulverized 150 mesh sieves).
9. the medicament of the conditioning alcoholic fatty liver as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Flos Daturae Flos Carthami to clean, drench and mix thoroughly into hydromel, be then placed in boiling container, with wine steaming and decocting 15-25 minute (preferred: with wine steaming and decocting 20 minutes), take out, dry at 50 DEG C;
(2) get Herba Polygalae Japonicae, Fructus Leonuri and Semen Arecae, by the rice vinegar spray profit of 10%, seal vexed 10-20 minute after (preferred: seal vexed 15 minutes) and cut sheet, be placed in parch container, slow fire heats, and fries to micro-yellow, take out dry in the air cool;
(3) Pericarpium Citri tangerinae is picked up clean impurity, spray clear water, runs through rear shredding, dries, pulverize, obtain medicated powder together with step (1) (2) made crude drug;
(4) by the crude drug beyond the foreign Jinhua of removing, Flos Carthami, Herba Polygalae Japonicae, Fructus Leonuri, Semen Arecae and Pericarpium Citri tangerinae, remove impurity, clean, be placed in marmite, add water and do not have medical material 3cm to soak 10 minutes, after moderate heat is boiled, constantly boiling 15 minutes, turns little fire and decocts 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes), filtered while hot, collects filtrate;
(5) by step (4) gained filtrate reduced in volume to thick paste, add step (3) gained medicated powder, stir, obtain unguentum.
10. the preparation method of the medicament unguentum of conditioning alcoholic fatty liver as claimed in claim 9, it is characterized in that, step is evaporated to relative density 1.22-1.28(55 DEG C in (5)) thick paste (preferred: the thick paste being evaporated to relative density 1.24-1.26; Be more preferably: be evaporated to the thick paste that relative density is 1.25).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510061461.4A CN104606462A (en) | 2015-02-06 | 2015-02-06 | Medicine for conditioning alcoholic fatty liver and preparation method of medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510061461.4A CN104606462A (en) | 2015-02-06 | 2015-02-06 | Medicine for conditioning alcoholic fatty liver and preparation method of medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104606462A true CN104606462A (en) | 2015-05-13 |
Family
ID=53141282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510061461.4A Pending CN104606462A (en) | 2015-02-06 | 2015-02-06 | Medicine for conditioning alcoholic fatty liver and preparation method of medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104606462A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115120634A (en) * | 2021-03-24 | 2022-09-30 | 中国科学院上海药物研究所 | Traditional Chinese medicine compound preparation for preventing and treating alcoholic liver injury and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1034136A (en) * | 1988-01-15 | 1989-07-26 | 中国人民解放军第六十九医院 | The production method of compound Chinese medicinal preparation " Sang Gedan " |
| CN104042847A (en) * | 2014-07-03 | 2014-09-17 | 成都九芝堂金鼎药业有限公司 | Lipid-lowering pills for treating hyperlipidaemia and preparation method thereof |
-
2015
- 2015-02-06 CN CN201510061461.4A patent/CN104606462A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1034136A (en) * | 1988-01-15 | 1989-07-26 | 中国人民解放军第六十九医院 | The production method of compound Chinese medicinal preparation " Sang Gedan " |
| CN104042847A (en) * | 2014-07-03 | 2014-09-17 | 成都九芝堂金鼎药业有限公司 | Lipid-lowering pills for treating hyperlipidaemia and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 何国权: "高脂血症的中药治疗", 《河南中医》 * |
| 朱鑫焱: "清脂汤治疗非酒精性脂肪性肝炎临床观察", 《中医药临床杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115120634A (en) * | 2021-03-24 | 2022-09-30 | 中国科学院上海药物研究所 | Traditional Chinese medicine compound preparation for preventing and treating alcoholic liver injury and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105477616A (en) | Medicine for easing mental anxiety, reducing phlegm, restoring consciousness and promoting blood circulation to remove meridian obstruction and preparation method thereof | |
| CN102698137A (en) | Composition with blood pressure reducing function and preparation method of same | |
| CN104958427A (en) | Traditional Chinese medicine used for treating dysmenorrhea caused by qi and blood deficiency | |
| CN102552779A (en) | Health-care traditional Chinese medicine composition with effect of human body blood purification and health-care product thereof | |
| CN104906507A (en) | Traditional Chinese medicine combination for lowering blood pressure and toning physical fitness | |
| CN103860773A (en) | Traditional Chinese medicine composition for treating myocardial ischemia and preparation method thereof | |
| CN107753602A (en) | A kind of Chinese medicine composition for treating leukaemia and preparation method thereof | |
| CN104042774A (en) | Medicine composition for treatment of osteoporosis | |
| CN104606462A (en) | Medicine for conditioning alcoholic fatty liver and preparation method of medicine | |
| CN104922499A (en) | Traditional Chinese medicine for treating hepatitis | |
| CN105435131A (en) | Traditional Chinese medicine composition for treating chronic heart failure and preparation method thereof | |
| CN105343688A (en) | Medicine composition for treating myocardial infarction and application thereof | |
| CN104758701A (en) | Medicament for nursing treatment of stomach stones after lithotripsy and preparation method of medicament | |
| CN104771585A (en) | Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof | |
| CN103536857B (en) | Traditional Chinese medicine for treating flaccid paralysis | |
| CN102218131A (en) | External Chinese herbal medicine composition for promoting tissue regeneration and knitting bones | |
| CN104689205A (en) | Traditional Chinese preparation for treating insomnia and dreamful sleep and preparation method thereof | |
| CN105688075A (en) | Novel oral preparation for treating stomachache and preparation method thereof | |
| CN104740396A (en) | Traditional Chinese medicine for treating kidney stones and preparation method of traditional Chinese medicine | |
| CN105456933A (en) | Traditional Chinese medicine capable of activating blood to remove stasis and clearing and activating channels and collaterals and preparation method of traditional Chinese medicine | |
| CN105288422A (en) | Traditional Chinese medicine preparation used for treating eilema syndromes and preparation method | |
| CN105582379A (en) | Traditional Chinese medicine composition for treating liver-stomach disharmony and preparation method of traditional Chinese medicine composition | |
| CN102973832B (en) | Medicament used for coronary heart disease and angina and preparation method of medicament | |
| CN105031335A (en) | Medicament for nursing and treatment after microwave pulverization of gastric bezoars and its preparation method | |
| CN105079319A (en) | Prescription for treating sciatica |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 024000 Inner Mongolia Chifeng City Hongshan iron Street No. 26 Qinghe District 5 Building 1 unit 401 Applicant after: Liu Yanling Address before: Song Liu village Huashan town Licheng District 250000 Shandong city of Ji'nan province No. 53 Applicant before: Liu Yanling |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150513 |
|
| RJ01 | Rejection of invention patent application after publication |