CN104547668A - Medicine for treating diabetes mellitus and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating diabetes mellitus. The medicine is prepared from the following medicinal raw materials in parts by weight: 10-20 parts of cuneate lespedeza herb with root, 10-30 parts of polygonum cuspidatum, 10-25 parts of kudzu vine root, 10-25 parts of radices trichosanthis, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of corn stigma and 10-20 parts of Japanese snakegourd root. The medicine is prepared by the following steps: weighing the raw materials according to the weight proportion, screening, washing, drying, grinding into powder, uniformly mixing, disinfecting and sterilizing, and filling capsules. The medicine has the effects of nourishing yin for lowering internal fire and promoting production of body fluid to relieve thirst, and has the characteristics of good curative effect, low reoccurrence rate and small side effect. Clinical application of the medicine on 1200 cases proves that the total effective rate is 92.8 percent, and the medicine is convenient and quick to use.

Description

A kind of medicine for the treatment of diabetes and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines, be specifically related to a kind of medicine for the treatment of diabetes, also relate to the preparation method of this medicine simultaneously.

Background technology

Diabetes are that in human body, insulin secretion reduces, and cause blood glucose caused by sugar, fat, protein, water and minerals metabolism disorder to increase, are more common in above middle age.Main manifestations is " three-many-one-little " (polydipsia, polyphagia, polyuria; Lose weight), belong to " diabetes " of motherland medical science, disease sees that three disappear and (above disappear: polydipsia; In disappear: polyphagia; Under disappear: polyuria).

Clinical treatment diabetes, oral western medicine treatment multiselect sulfonylurea drugs, biguanides, α glucosidase inhibitor, euglycemic agent, meglitinide Insulin secretagogues; Next selects insulinize, and insulin preparation has animal insulin, insulin human and insulin analog.According to being divided into fugitive, middle effect and protamine zine insulin action time, and making mix preparation, as Novolin 30R, excellently secreting woods 70/30; 3rd is exercise therapy, and four fundamental rules are Diet Therapys.

Select diabetes treatment by western medicine, although can produce certain or good control action to the state of an illness, mostly side effect is large, and hepatic and renal function may be caused to damage, and drug dependence is strong, and patient need be taken medicine all the life.

Along with the development of Chinese Medicine Industry, increasing Chinese crude drug formula is disclosed, and effect, lays particular stress on different, and curative effect is also uneven.

China Patent Publication No. is that the file of CN103656051A discloses " a kind of Chinese medicine for the treatment of diabetes ", the raw material preparing this active ingredient of Chinese herbs comprises by weight: Radix Puerariae 11-15 part, Radix Rehmanniae 16-24 part, Radix Astragali 20-30 part, Poria 14-27 part, Fructus Schisandrae Chinensis 22-33 part, Rhizoma Polygoni Cuspidati 21-40 part, Cortex Lycii 23-36 part, Fructus Mume 17-32 part, Radix Trichosanthis 16-25 part, Fructus Corni 14-25 part, Rhizoma Dioscoreae 15-19 part.

China Patent Publication No. is that the file of CN103920028A discloses " a kind of treat the pharmaceutical composition of diabetes and the preparation method of preparation thereof ", relates to the medicines such as Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis, Gypsum Fibrosum, the Radix Rehmanniae, the Rhizoma Anemarrhenae, Radix Trichosanthis, Radix Puerariae, Herba Patriniae, Herba Andrographis, Rhizoma Coptidis, Cortex Mori, Rhizoma Polygonati Odorati, the Rhizoma Atractylodis Macrocephalae, Herba Taraxaci Rhizoma Dioscoreae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Fructus Lycii, Radix Scrophulariae, Cortex Lycii, Fructus Crataegi, Radix Glycyrrhizae, Radix Rehmanniae, Stigma Maydis and makes Chinese medicine preparation.

Above Chinese medicine formula, use flavour of a drug more, specific aim is not strong.

Herba Lespedezae Cuneatae, Classification system: herba Lespedezae Cuneatae, leguminous plant;

Rhizoma Polygoni Cuspidati, Classification system: reynoutria japonica Houtt, polygonaceae plant;

Radix Puerariae, Classification system: lobed Kudzuvine Root, leguminous plant;

Radix Trichosanthis, cucurbitaceous plant Fructus Trichosanthis trichosanthes kirilowii Maximor trichosanthes rosthornii Harms trichosan-thes rosthornii Hermsdry root;

The Rhizoma Anemarrhenae, Classification system: anemarrhena asphodeloides Bunge, liliaceous plant;

Stigma Maydis, grass Semen Maydis zeamaysLstyle and stigma.

Radix Trichosanthis Cucumeroidis, the root of cucurbitaceous plant Fructus Trichosanthis Cucumeroidis Trichosanthes cucumeroides (Ser.) Maxim.

Summary of the invention

The object of the present invention is to provide the medicine of the treatment diabetes that a kind of good effect, relapse rate are low, side effect is little.

Another object of the present invention is to provide this treatment to treat the preparation method of the medicine of diabetes.

A kind of medicine for the treatment of diabetes of the present invention, is obtained by the crude drug of following weight parts: Herba Lespedezae Cuneatae 10-20 part, Rhizoma Polygoni Cuspidati 10-30 part, Radix Puerariae 10-25 part, Radix Trichosanthis 10-25

Part, Rhizoma Anemarrhenae 10-20 part, Stigma Maydis 10-20 part, Radix Trichosanthis Cucumeroidis 10-20 part.

Treat a medicine for diabetes as above, wherein, preferred weight part of each crude drug is:

Herba Lespedezae Cuneatae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Puerariae 18 parts, Radix Trichosanthis 18 parts, the Rhizoma Anemarrhenae 15 parts, Stigma Maydis 15 parts, Radix Trichosanthis Cucumeroidis 15 parts.

A kind of preparation method for the treatment of the medicine of diabetes of the present invention, comprises the following steps:

(1) screen crude drug, sample by weight, cleaning, dry, be ground into powder, cross 100-120 mesh sieve;

(2) after mix homogeneously through sterilization, incapsulate, every dress powder 0.4g and get final product.

Medicine of the present invention adds required adjuvant according to a conventional method, can be made into other dosage forms such as tablet, pill.

The present invention compared with prior art, has obvious beneficial effect, as can be known from the above technical solutions: the present invention selects Herba Lespedezae Cuneatae, Rhizoma Polygoni Cuspidati, Radix Puerariae, Radix Trichosanthis, the Rhizoma Anemarrhenae, Stigma Maydis, Radix Trichosanthis Cucumeroidis to be raw material, treats diabetes by the synergism of each medicine.Select the Miao Ethnomedicine prescription of nourishing YIN to lower pathogenic fire, promoting the production of body fluid to quench thirst, fundamentally can cure disease.Its expense is low, good effect, relapse rate are low, side effect is little, and medication is convenient and swift.Clinical 1200 examples use, and sanatory total effective rate is 92.8%.

Detailed description of the invention

The beneficial effect of medicine of the present invention is set forth further below by way of test example.

test example:the clinical observation of medicine of the present invention

Clinical data:

All cases 1200 example, wherein male 700 example, women 500 example, max age 86 years old, minimal ages 8 years old.

Diagnostic criteria:

" disease of tcm Standardization of diagnosis and curative effect "

Using method:

Every day 3 times, each 4, early, middle and lately respectively taking 1 time, was 1 course for the treatment of through 3 months, 1-2 the course for the treatment of.

Criterion of therapeutical effect:

Effective: transference cure.

Effective: symptom is obviously alleviated.

Invalid: symptom is without improvement.

Therapeutic outcome:

1200 routine diabeticss use medicine of the present invention, effective 997 examples, effective 116 examples, invalid 7 examples, obvious effective rate 83%, total effective rate 92.8%.

embodiment 1

A kind of medicine for the treatment of diabetes of the present invention, comprises the following steps:

(1) screen crude drug, take Herba Lespedezae Cuneatae 10g, Rhizoma Polygoni Cuspidati 10g, Radix Puerariae 10g, Radix Trichosanthis 10g, Rhizoma Anemarrhenae 10g, Stigma Maydis 10g, Radix Trichosanthis Cucumeroidis 10g, cleaning, dry, be ground into powder, cross 100 mesh sieves;

(2) after mix homogeneously through sterilization, incapsulate, every dress powder 0.4g and get final product.

embodiment 2

A kind of medicine for the treatment of diabetes of the present invention, comprises the following steps:

(1) screen crude drug, take Herba Lespedezae Cuneatae 20g, Rhizoma Polygoni Cuspidati 30g, Radix Puerariae 25g, Radix Trichosanthis 25g, Rhizoma Anemarrhenae 20g, Stigma Maydis 20g, Radix Trichosanthis Cucumeroidis 20g, cleaning, dry, be ground into powder, cross 120 mesh sieves;

(2) after mix homogeneously through sterilization, incapsulate, every dress powder 0.4g and get final product.

embodiment 3

A kind of medicine for the treatment of diabetes of the present invention, comprises the following steps:

(1) screen crude drug, take Herba Lespedezae Cuneatae 15g, Rhizoma Polygoni Cuspidati 20g, Radix Puerariae 18g, Radix Trichosanthis 18g, Rhizoma Anemarrhenae 15g, Stigma Maydis 15g, Radix Trichosanthis Cucumeroidis 15g, cleaning, dry, be ground into powder, cross 110 mesh sieves;

(2) after mix homogeneously through sterilization, incapsulate, every dress powder 0.4g and get final product

The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, anyly do not depart from technical solution of the present invention content, the any simple modification done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.

Claims (3)

1. treat a medicine for diabetes, obtained by the crude drug of following weight parts: Herba Lespedezae Cuneatae 10-20 part, Rhizoma Polygoni Cuspidati 10-30 part, Radix Puerariae 10-25 part, Radix Trichosanthis 10-25 part, Rhizoma Anemarrhenae 10-20 part, Stigma Maydis 10-20 part, Radix Trichosanthis Cucumeroidis 10-20 part.

2. a kind of medicine for the treatment of diabetes as claimed in claim 1, is characterized in that: obtained by the crude drug of following weight parts: Herba Lespedezae Cuneatae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Puerariae 18 parts, Radix Trichosanthis 18 parts, the Rhizoma Anemarrhenae 15 parts, Stigma Maydis 15 parts, Radix Trichosanthis Cucumeroidis 15 parts.

3. a kind of preparation method for the treatment of the medicine of diabetes as claimed in claim 1 or 2, comprises the following steps:

(1) screen crude drug, sample by weight, cleaning, dry, be ground into powder, cross 100-120 mesh sieve;

(2) after mix homogeneously through sterilization, incapsulate, every dress powder 0.4g and get final product.