CN104491945B - A kind of sampled plasma device - Google Patents
A kind of sampled plasma device Download PDFInfo
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- CN104491945B CN104491945B CN201410854903.6A CN201410854903A CN104491945B CN 104491945 B CN104491945 B CN 104491945B CN 201410854903 A CN201410854903 A CN 201410854903A CN 104491945 B CN104491945 B CN 104491945B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
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- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
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- Anesthesiology (AREA)
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- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses a kind of sampled plasma device, including the syringe needle for blood collection, connector one, the first puncture outfit for accessing anti-coagulants, the anti-coagulants pipeline being connected with the first puncture outfit, blood filter, the transducer potector being connected with blood filter, for the Centrifuge Cup of separated plasma, connector two, blood plasma collecting bag, the second puncture outfit for accessing physiological saline, anticoagulant pump, blood pump and the air probe one for detecting air, air probe two, air probe three and air probe four, on transducer potector between connector one and blood filter air probe one and air probe two are sequentially provided with along the direction for extracting blood；Anti-coagulants pipeline between anticoagulant pump and connector one is provided with air probe three；Transducer potector between blood filter and blood pump is provided with air probe four；Sampled plasma device of the invention, can detect the air and pressure in red blood cell, the pipeline in Centrifuge Cup exit in collection and returning step.
Description
Technical field
The invention belongs to technical field of medical equipment, and in particular to a kind of sampled plasma device.
Background technology
Slurry is adopted, full name is Plasma Pheresis/Apheresis Plasma, refer to and human whole blood is gone out blood plasma by physical method for separation, and by remaining component also
A defeated process in plasma donor body.
Blood-collecting station, is set up through examination ＆ approval, the unit of collection supply blood product production raw blood plasma.Last decade
Come, with being stepped up for China's blood product output, various regions are provided with a large amount of blood-collecting stations in succession, to ensure blood system
Product production raw material.
After medical fitness and meet offer slurry require personnel can turn into offer slurry personnel.In order to ensure to offer slurry personnel's
Health, national correlation department regulation：Everyone is gathered plasma volume and (containing anti-coagulants solution, must not be converted with volume more than 580ml every time
600g is no more than into quality)；Adopting slurry interval must not be shorter than 14 days.
Sampled plasma device has been widely used for blood-collecting station, Blood Center or medical usage, sampled plasma at present
The effect of device is exactly to be separated blood constituent according to the difference of blood constituent density, obtains high-quality blood plasma, and really
The other compositions for protecting blood are injury-free, safely feed back in plasma donor body.The blood plasma of collection is if red blood cell has been mixed into
The quality of blood plasma can be influenceed, forbids air to enter blood when feeding back red blood cell, prevent from forming air embolism at hemadostewnosis, hindered
Blood circulation path, causes shock, and during collection and feedback, if blood pump rotating speed is too fast, human body is produced
Negative pressure and malleation is too high can cause the discomfort of plasma donor.
The content of the invention
Present invention aim to address above mentioned problem, there is provided one kind can detect Centrifuge Cup outlet in collection and returning step
The sampled plasma device of air and pressure in red blood cell, the pipeline at place.
In order to solve the above technical problems, the technical scheme is that：A kind of sampled plasma device, including adopted for blood
Anti-coagulants pipeline, blood filter and blood mistake that the syringe needle of collection, connector one, the first puncture outfit are connected with the first puncture outfit
Filter connected transducer potector, the Centrifuge Cup for separated plasma, connector two, blood plasma collecting bag, the second puncture outfit, anti-coagulants
Pump, blood pump and air probe one, air probe two, air probe three and air probe four for detecting air；The pin
Head, anti-coagulants pipeline, blood filter are connected with connector one respectively, and the blood filter passes through transducer potector and Centrifuge Cup
Import be connected；The outlet respectively with Centrifuge Cup of the connector two, blood plasma collecting bag and the second puncture outfit are connected；The anti-freezing
Agent pipeline is arranged on anticoagulant pump, and the transducer potector between blood filter and Centrifuge Cup is arranged on blood pump；The connection
On transducer potector between part one and blood filter air probe one and air spy are sequentially provided with along the direction for extracting blood
First two；Anti-coagulants pipeline between anticoagulant pump and connector one is provided with air probe three；Between blood filter and blood pump
Transducer potector be provided with air probe four.
Preferably, also including the red blood cell detector on the transducer potector between connector two and Centrifuge Cup.
Preferably, the also pressure detector including being connected with blood filter.
Preferably, also including the valve one on the transducer potector between blood filter and air probe four, located at even
Valve two between fitting two and blood plasma collecting bag, and the valve three between the puncture outfit of connector two and second.
Preferably, also including the electronic scale for weighing blood plasma collecting bag quality.
Preferably, also including position limiting clamp, anti-coagulants pipeline and transducer potector are installed on position limiting clamp.
Preferably, the connector one and connector two are three-way connection.
Preferably, first puncture outfit is connected for accessing anti-coagulants, the second puncture outfit and physiology salt with anti-coagulants bag
Water bottle is connected for accessing physiological saline.
The beneficial effects of the invention are as follows：Sampled plasma device provided by the present invention, it is several on pipeline by being arranged on
Air probe can detect the air gathered with pipeline in returning step, prevent air intravasation from being caused damage to human body；
Red blood cell is detected by the red blood cell detector being arranged between Centrifuge Cup and connector two, prevents red blood cell from entering plasma collection
Bag influence acquisition quality；The pressure in collection and returning step is detected by the pressure detector being connected with blood filter, is prevented
The discomfort that only hypertonia is caused to human body.
Brief description of the drawings
Fig. 1 is the structural representation of sampled plasma device of the present invention.
Description of reference numerals：1st, syringe needle；2nd, connector one；3rd, the first puncture outfit；4th, anti-coagulants pipeline；5th, blood filtration
Device；6th, transducer potector；7th, Centrifuge Cup；8th, connector two；9th, blood plasma collecting bag；10th, the second puncture outfit；11st, anticoagulant pump；12、
Blood pump；13rd, air probe one；14th, air probe two；15th, air probe three；16th, valve one；17th, air probe four；18th, it is red
Cell detection device；19th, valve two；20th, valve three；21st, position limiting clamp；22nd, pressure detector；23rd, electronic scale.
Specific embodiment
The present invention is described further with specific embodiment below in conjunction with the accompanying drawings：
As shown in figure 1, sampled plasma device of the invention, including syringe needle 1, connector one 2, first for blood collection
The anti-coagulants pipeline 4 that puncture outfit 3 is connected with the first puncture outfit 3, the blood filtration for filtering particulate and azelon in consumptive material
Transducer potector 6 that device 5 is connected with blood filter 5, the Centrifuge Cup 7 for separated plasma, connector 28, blood plasma collecting bag 9,
Second puncture outfit 10, anticoagulant pump 11, blood pump 12 and air probe 1, air probe 2 14, sky for detecting air
Gas probe 3 15 and air probe 4 17；First puncture outfit 3 is connected for accessing anti-coagulants, the second puncture outfit 10 with anti-coagulants bag
It is connected for accessing physiological saline with normal saline bottle.
Connector 1 and connector 28 are three-way connection, syringe needle 1, anti-coagulants pipeline 4, blood filter 5 respectively with even
Fitting 1 is connected, and blood filter 5 is connected by transducer potector 6 with the import of Centrifuge Cup 7；Connector 28 respectively with Centrifuge Cup
7 outlet, blood plasma collecting bag 9 are connected with the second puncture outfit 10；Slightly stabilization is suspended on the support arm of electronic scale 23 to blood plasma collecting bag 9
On, electronic scale 23 can in real time weigh the mass of blood plasma collecting bag 9, and during collection, electronic scale detects quality (including blood plasma collecting bag 9
Quality) more than 680g, machine warning " electronic scale quality is excessive ".
Anti-coagulants pipeline 4 and transducer potector 6 are transparent hose, and anti-coagulants pipeline 4 is arranged on anticoagulant pump 11, blood mistake
Transducer potector 6 between filter 5 and Centrifuge Cup 7 is arranged on blood pump 12；Whole blood is sent into by Centrifuge Cup by the operating of blood pump 12
7, or human body is returned to by the red blood cell after separation is defeated；In order that pipeline and pump preferably coordinate, anticoagulant pump 11 and blood pump 12
Both sides are equipped with position limiting clamp 21, and anti-coagulants pipeline 4 and transducer potector 6 are arranged on position limiting clamp 21 and position.
Air of the air probe in responsible signal piping in machine operation, vital work is played to Blood donation safety
With its operation principle is：Air probe is according to ultrasonic wave principle, using the difference of ultrasonic wave transmission speed in liquids and gases
It is different to recognize gas and liquid.
On transducer potector 6 between connector 1 and blood filter 5 air is sequentially provided with along the direction for extracting blood
Pop one's head in one 13 and air probe 2 14；Transducer potector 6 between blood filter 5 and blood pump 12 is provided with air probe 4 17；
Traditional slurry of adopting is divided into three circulations, and when feeding back for the first time and for the second time, air probe 4 17 is stopped when detecting air
Non-return is defeated；When last time feeds back, air probe 1 and air probe 2 14 any one stop when detecting air
Non-return is defeated；During each circle collection, blood pump 12 is started counting up to 330 circles after air probe 4 17 detects liquid, electronic scale
The increase of plasma purity is not detected by, machine can be warned " crossing non-pulp for a long time ".
Anti-coagulants pipeline 4 between anticoagulant pump 11 and connector 1 is provided with air probe 3 15；In gatherer process,
Air probe 3 15 finds to send air alarm signal during air, and prompting operating personnel's anti-coagulants is finished or anti-freezing pipeline is provided with
Problem.
Acquisition quality, blood tube between connector 28 and Centrifuge Cup 7 are influenceed in order to prevent red blood cell from entering blood plasma collecting bag
Road 6 is provided with red blood cell detector 18, and red blood cell detector 18 is the critical component for ensureing to adopt slurry quality, is a kind of photoelectric sensing
Device, it is according to the difference of light propagation characteristic in different colours liquid come detection zone dividend cell and blood plasma.
For the discomfort for preventing hypertonia from being caused to human body, blood filter 5 is connected with pressure detector 22, and pressure is visited
It is to ensure the important component for offering slurry safety to survey device 22, and pressure detector 22 is used to detect the pressure in collection and returning step, when
Machine sends warning during higher than setting value, and operating personnel can reduce pressure by adjusting the rotating speed of blood pump 12.
Transducer potector 6 is provided with valve 1, connector 28 and blood plasma between blood filter 5 and air probe 4 17
Valve 2 19 is provided between collecting bag 9, valve 3 20 is provided between the puncture outfit 10 of connector 28 and second, collection blood plasma when
Wait, open valve 1 and valve 2 19, close valve 3 20, whole blood is flowed into Centrifuge Cup 7, separated blood by blood pump 12
Slurry flows into blood plasma collecting bag 9 by the valve 2 19 opened；When feeding back red blood cell, the user to requiring supplementation with water increased
One valve 3 20, closes valve 2 19, opens valve 1 and valve 3 20, and the physiological saline that the second puncture outfit 10 is accessed is returned
It is defeated to human body.
The course of work of above-mentioned sampled plasma device is：
Sampled plasma device is opened, syringe needle 1 is inserted into human body, will mix anti-by the operation of anticoagulant pump 11 and blood pump 12
The whole blood feeding Centrifuge Cup 7 of solidifying agent is centrifuged.As the speed of Centrifuge Cup 7 increases, whole blood is progressively layered, larger thin of density
Born of the same parents are split into outer layer.Blood plasma can be exported from Centrifuge Cup 7 and overflowed after Centrifuge Cup 7 is full of by separate whole blood, by red thin
After the detection of born of the same parents' detector 18 enter blood plasma collecting bag 9 in, by electronic scale 23 detect overflow blood plasma number；When electronic scale 23 is examined
Measure after the blood plasma in blood plasma collecting bag 9 reaches preset value, stop the operation of anticoagulant pump 11, blood pump 12 and Centrifuge Cup 7, terminate
The circle collection task.Start to feed back red blood cell after Centrifuge Cup 7 stops operating, the antikinesis of blood pump 12 is by Centrifuge Cup 7
Red blood cell etc. feeds back the Huis' body.Liquid case in the continuous signal piping of air probe in returning step, once find air
To send and warn and stop to feed back.Start the collecting work of subsequent cycle, so circulation after feedback is finished.
One of ordinary skill in the art will be appreciated that embodiment described here is to aid in reader and understands this hair
Bright principle, it should be understood that protection scope of the present invention is not limited to such especially statement and embodiment.This area
Those of ordinary skill can according to these technical inspirations disclosed by the invention make it is various do not depart from essence of the invention other are each
Plant specific deformation and combine, these deformations and combination are still within the scope of the present invention.
Claims (7)
1. a kind of sampled plasma device, it is characterised in that:Including the syringe needle (1) for blood collection, connector one (2), first
Anti-coagulants pipeline (4), blood filter (5) and blood filter (5) phase that puncture outfit (3) is connected with the first puncture outfit (3)
Transducer potector (6), the Centrifuge Cup (7) for separated plasma, connector two (8), blood plasma collecting bag (9), the second puncture outfit even
(10), anticoagulant pump (11), blood pump (12) and air probe one (13), air probe two (14), sky for detecting air
Gas probe three (15) and air probe four (17)；
The syringe needle (1), anti-coagulants pipeline (4), blood filter (5) are connected with connector one (2) respectively, the blood filtration
Device (5) is connected by transducer potector (6) with the import of Centrifuge Cup (7)；The connector two (8) goes out with Centrifuge Cup (7) respectively
Mouth, blood plasma collecting bag (9) are connected with the second puncture outfit (10)；
The anti-coagulants pipeline (4) on anticoagulant pump (11), the blood between blood filter (5) and Centrifuge Cup (7)
Pipeline (6) is on blood pump (12)；
Set successively along the direction for extracting blood on transducer potector (6) between the connector one (2) and blood filter (5)
There are air probe one (13) and air probe two (14)；Anti-coagulants pipeline (4) between anticoagulant pump (11) and connector one (2)
It is provided with air probe three (15)；Transducer potector (6) between blood filter (5) and blood pump (12) is provided with air probe four
(17)；Also include the electronic scale (23) for weighing blood plasma collecting bag (9) quality；Adopt slurry and be divided into three circulations, when for the first time and
When feedback for second, air probe four (17) stops feeding back when detecting air；When last time feeds back, air
Probe one (13) and air probe two (14) any one stop feedback when detecting air；During each circle collection, air is visited
First four (17) detect blood pump (12) after liquid starts counting up to 330 circles, and electronic scale (23) is not detected by the increasing of plasma purity
Plus, machine warning.
2. sampled plasma device according to claim 1, it is characterised in that:Also include located at connector two (8) and centrifugation
Red blood cell detector (18) between cup (7) on transducer potector (6).
3. sampled plasma device according to claim 1, it is characterised in that:Also include what is be connected with blood filter (5)
Pressure detector (22).
4. according to any described sampled plasma device of claims 1 to 3, it is characterised in that:Also include being located at blood filter
(5) valve one (16) and air probe four (17) between on transducer potector (6), located at connector two (8) and blood plasma collecting bag
(9) valve two (19) between, and the valve three (20) between connector two (8) and the second puncture outfit (10).
5. according to any described sampled plasma device of claims 1 to 3, it is characterised in that:Also include position limiting clamp (21), anti-freezing
Agent pipeline (4) and transducer potector (6) are installed on position limiting clamp (21).
6. according to any described sampled plasma device of claims 1 to 3, it is characterised in that:The connector one (2) and connection
Part two (8) is three-way connection.
7. according to any described sampled plasma device of claims 1 to 3, it is characterised in that:First puncture outfit (3) with it is anti-
Solidifying agent bag is connected for accessing anti-coagulants, and the second puncture outfit (10) is connected for accessing physiological saline with normal saline bottle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410854903.6A CN104491945B (en) | 2014-12-31 | 2014-12-31 | A kind of sampled plasma device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410854903.6A CN104491945B (en) | 2014-12-31 | 2014-12-31 | A kind of sampled plasma device |
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| Publication Number | Publication Date |
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| CN104491945A CN104491945A (en) | 2015-04-08 |
| CN104491945B true CN104491945B (en) | 2017-06-06 |
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| CN201410854903.6A Active CN104491945B (en) | 2014-12-31 | 2014-12-31 | A kind of sampled plasma device |
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| CN105498010B (en) * | 2016-01-13 | 2019-01-11 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collecting and separating device and method |
| CN105950457A (en) * | 2016-03-15 | 2016-09-21 | 绍兴市人民医院 | Apparatus for enriching stem cells |
| CN107790298A (en) * | 2016-08-29 | 2018-03-13 | 赛若麦得（上海）生物技术有限公司 | A kind of sampled plasma device and its control method |
| CN106913918A (en) * | 2017-03-29 | 2017-07-04 | 艾沃生物科技（苏州）有限公司 | A kind of external circulating therapy centrifugal plasma isolation of purified instrument |
| CN110859635A (en) * | 2019-10-18 | 2020-03-06 | 四川南格尔生物科技有限公司 | Plasma sampling pipeline system and sampling method |
| CN110613869B (en) * | 2019-10-24 | 2024-07-26 | 成都市佳颖医用制品有限公司 | Plasma exchange adsorption system |
| CN116392857A (en) * | 2023-06-08 | 2023-07-07 | 深圳赛桥生物创新技术有限公司 | Sample collection method and device |
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Address after: 610100 No. 138 Wuxing Street, Damian Street, Longquanyi District, Chengdu City, Sichuan Province Patentee after: CHENGDU JIAYING MEDICAL PRODUCT CO., LTD. Address before: 610100 Wuxing Street, Damian Street, Longquanyi District, Chengdu City, Sichuan Province Patentee before: CHENGDU JIAYING MEDICAL PRODUCT CO., LTD. |