CN104489296A - Functional feed for preventing piglet oedema disease, and preparation method thereof - Google Patents
Functional feed for preventing piglet oedema disease, and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a functional feed for preventing the piglet oedema disease, and a preparation method thereof. The functional feed comprises corn, soybean meal, broad bean, Semen Phaseoli, fish meal, white gourd peel, plasma protein powder, a micro-ecologic preparation, salt, soybean oil, a trace element premix, a vitamin premix and a traditional Chinese medicinal additive. The traditional Chinese medicinal additive contained in the feed has the main efficacies of heat clearing, detoxifying, water retention alleviating, swelling eliminating and lung diffusing, has the auxiliary efficacies of spleen invigorating, dampness transforming, kidney warming, mind tranquilizing and mind calming, cooperates with other feed raw materials, and acts together, so the functional feed for preventing the piglet oedema disease has the advantages of good prevention and treatment effect, fast effectiveness, definite therapeutic effect, no drug resistance, no recurrence, few side effects, low drug residual and the like.
Description
Technical field
The present invention relates to pig starter feed, particularly relate to a kind of for functional feed preventing hydropsy for baby pigs and preparation method thereof.
Background technology
Bowel oedema disease, also known as colitoxemia, edema disease, gastric edema, is the disease of a kind of acute, lethal of piggy, it is characterized by coat of the stomach and oedema occurs at some other position.This disease mainly betides delactational piglets, and little of age a few days, there is generation at greatly to 4 monthly age.The piglet that growth is fast, body condition is healthy and strong is the most common, and modest piglet occurs less.The sow that carries disease germs is propagated to piglet, in endemic conditions, is often limited to the piglet of some pig farm and some nest.Diet method changes, and feed is single, climate change, the water after contaminated, environment, and apparatus etc. all can cause the chance of occurrence of this disease to increase.
Main clinic symptoms has: sick pig sudden onset, and spirit is depressed, poor appetite, mouth stream foam, and body temperature, without significant change, has laxativeness in 1-2 days, rear constipation before sick.Heartbeat quickly, is breathed just fast and shallow, dark slowly afterwards.The sleeping ground of happiness, muscular tremor, twitch frequently, and major beat swimming shape, groan, haunch when standing, shakes.Forelimb is as benumbed, then astasia, hindlimb paralysis, then can not stand.Weakness of limbs during walking, incoordination, gait waves shakiness, blindly advances or makes circular motion.Oedema is the characteristic symptom of this disease, be common in face, eyelid, conjunctiva, gums, neck, belly subcutaneous.The sick pig had does not have the change of oedema.Main manifestations is sudden onset, and body temperature is not high, quadruped locomotion obstacle, and rear quarters is unable, waves and incoordination; The sick pig had does circular motion or blindly disorderly punching, suddenly violent body wash-ahead; When various stimulation or seizure, the scream of touching, calls hoarse, falls down to the ground, and four limbs are disorderly dynamic, shape of seemingly swimming; The sick common face of pig, palpebral edema, severe one is extended down to face, neck, and head becomes fat.
Distinctive pathology is coat of the stomach, colon mesenterium, eyelid and face and submandibular lymph nodes oedema.Food is full of, mucous membrane flush in stomach, sometimes hemorrhage, there is the transparent oedema of thick-layer under the mucous membrane of stomach base area, have the gel-shaped oedema of band blood to infiltrate, mucous membrane is separated with muscle layer, reached at 2-3 centimetre that oedema is serious, serious involved orifice of the stomach district and Pyloric Region.Also often have oedema around large mesenterium, gall-bladder, larynx, rectum, lymph node oedema, hyperemia, hemorrhage, pericardium and splanchnocoel have more hydrops, and exposure air then congeals into gelatin.Kidney peplos oedema, mucous membrane of urinary bladder hyporrhea, hemorrhagic enteritis change is common.
The medicine of current treatment hydropsy for baby pigs mostly is Western medicine as kanamycin sulfate, although have certain result for the treatment of, DeGrain, and can not play the effect of prevention, and antibiotics exists the problems such as medicament residue.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for functional feed preventing hydropsy for baby pigs and preparation method thereof, the Chinese medicine additive that feed of the present invention contains is based on clearing heat and detoxicating, inducing diuresis for removing edema, freeing lung-Qi and eliminating damp, be auxiliary with invigorating the spleen for eliminating dampness, warm kidney, tranquilizing the mind, control hydropsy for baby pigs have that prevention effect is good, instant effect, determined curative effect, do not develop immunity to drugs, the advantage such as not easily recurrence, few side effects, drug residue are low.
In order to realize foregoing invention object, the invention provides a kind of for preventing the functional feed of hydropsy for baby pigs, described feed comprises following raw material: corn, dregs of beans, broad bean, red bean, fish meal, waxgourd peel, SDPP, probiotics, salt, soybean oil, microelement pre-mix material, vitamin premix and Chinese medicine additive.
Described feed is made up of the raw material of following parts by weight: corn 35-55 weight portion, dregs of beans 18-35 weight portion, broad bean 20-35 weight portion, red bean 15-20 weight portion, fish meal 10-15 weight portion, waxgourd peel 10-18 weight portion, SDPP 5-10 weight portion, probiotics 0.1-0.5 weight portion, salt 1-3 weight portion, soybean oil 1-3 weight portion, microelement pre-mix material 0.01-0.05 weight portion, vitamin premix 0.01-0.05 weight portion and Chinese medicine additive 3-7 weight portion.
Described feed is preferably made up of the raw material of following parts by weight: corn 48 weight portion, dregs of beans 23 weight portion, broad bean 27 weight portion, red bean 17 weight portion, fish meal 12 weight portion, waxgourd peel 14 weight portion, SDPP 7 weight portion, probiotics 0.3 weight portion, salt 2 weight portion, soybean oil 2 weight portion, microelement pre-mix material 0.02 weight portion, vitamin premix 0.02 weight portion and Chinese medicine additive 5 weight portion.
Described probiotics is one or both in bacillus and lactic acid bacteria; Described vitamin premix is one or more in vitamin A, D3, E, K3, B1, B2, B6, folic acid, pantothenic acid, nicotinic acid; Described microelement pre-mix material is one or more in copper, iron, manganese, zinc, iodine, selenium.
Described Chinese medicine additive comprises following raw medicinal material: cape jasmine, Dysosma versipellis, dandelion, Japanese Stephania Root, dindygulen peperomia herb, Radix Isatidis, Chinese violet, Herba Hyperici Patuli, Scirpus tabernaemontani, repent jussiaea herb, fishing rod, water hyacinth root, almond and raphani,radix.
Described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: cape jasmine 20-30 weight portion, Dysosma versipellis 12-21 weight portion, dandelion 15-30 weight portion, Japanese Stephania Root 10-19 weight portion, dindygulen peperomia herb 8-15 weight portion, Radix Isatidis 10-20 weight portion, Chinese violet 5-15 weight portion, Herba Hyperici Patuli 8-17 weight portion, Scirpus tabernaemontani 9-21 weight portion, repent jussiaea herb 8-20 weight portion, fishing rod 5-15 weight portion, water hyacinth root 10-20 weight portion, almond 10-20 weight portion and raphani,radix 10-15 weight portion.
Described Chinese medicine additive is preferably made up of the raw medicinal material of following parts by weight: cape jasmine 26 weight portion, Dysosma versipellis 17 weight portion, dandelion 21 weight portion, Japanese Stephania Root 15 weight portion, dindygulen peperomia herb 12 weight portion, Radix Isatidis 15 weight portion, Chinese violet 10 weight portion, Herba Hyperici Patuli 14 weight portion, Scirpus tabernaemontani 15 weight portion, repent jussiaea herb 15 weight portion, fishing rod 10 weight portion, water hyacinth root 14 weight portion, almond 17 weight portion and raphani,radix 13 weight portion.
Described Chinese medicine additive also comprises Poria cocos, the bighead atractylodes rhizome, radix fici simplicissimae, breast flower, dried human placenta, the red sage root, arisaema cum bile and oeder plagiopus herb, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: cape jasmine 20-30 weight portion, Dysosma versipellis 12-21 weight portion, dandelion 15-30 weight portion, Japanese Stephania Root 10-19 weight portion, dindygulen peperomia herb 8-15 weight portion, Radix Isatidis 10-20 weight portion, Chinese violet 5-15 weight portion, Herba Hyperici Patuli 8-17 weight portion, Scirpus tabernaemontani 9-21 weight portion, repent jussiaea herb 8-20 weight portion, fishing rod 5-15 weight portion, water hyacinth root 10-20 weight portion, almond 10-20 weight portion, raphani,radix 10-15 weight portion, Poria cocos 10-25 weight portion, bighead atractylodes rhizome 10-15 weight portion, radix fici simplicissimae 10-20 weight portion, breast flower 10-20 weight portion, dried human placenta 10-15 weight portion, red sage root 10-22 weight portion, arisaema cum bile 10-15 weight portion and oeder plagiopus herb 10-20 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: cape jasmine 26 weight portion, Dysosma versipellis 17 weight portion, dandelion 21 weight portion, Japanese Stephania Root 15 weight portion, dindygulen peperomia herb 12 weight portion, Radix Isatidis 15 weight portion, Chinese violet 10 weight portion, Herba Hyperici Patuli 14 weight portion, Scirpus tabernaemontani 15 weight portion, repent jussiaea herb 15 weight portion, fishing rod 10 weight portion, water hyacinth root 14 weight portion, almond 17 weight portion, raphani,radix 13 weight portion, Poria cocos 18 weight portion, the bighead atractylodes rhizome 12 weight portion, radix fici simplicissimae 15 weight portion, breast spends 15 weight portions, dried human placenta 12 weight portion, the red sage root 16 weight portion, arisaema cum bile 13 weight portion and oeder plagiopus herb 15 weight portion.
The preparation method of described Chinese medicine additive is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds the starch relative to its quality 2 ~ 4 times in the micropowders obtained by second step, mixing, obtains powder.
In order to better realize foregoing invention object, the invention provides a kind of preparation method of the feed for preventing and treating hydropsy for baby pigs, wherein, the preparation method of described feed is:
Pulverising step: take corn, dregs of beans, broad bean, red bean, fish meal and waxgourd peel by weight, drops into pulverizer and pulverizes;
Blend step: by weight by after SDPP, salt, soybean oil, microelement pre-mix material, vitamin premix and Chinese medicine additive premixed, more fully mix with the comminuting matter obtained in pulverising step;
Granulation step: drop into granulator, granulates, makes its gelatinization degree reach 90% at 70-80 DEG C;
Spraying process: the surface by weight percentage probiotics being sprayed to pellet.
The invention has the beneficial effects as follows: the Chinese medicine additive that feed of the present invention contains is based on clearing heat and detoxicating, inducing diuresis for removing edema, freeing lung-Qi and eliminating damp, be auxiliary with invigorating the spleen for eliminating dampness, warm kidney, tranquilizing the mind, cooperatively interact with other feedstuffs, acting in conjunction, control hydropsy for baby pigs has that prevention effect is good, instant effect, determined curative effect, do not develop immunity to drugs, the advantage such as not easily recurrence, few side effects, drug residue are low.
Detailed description of the invention
Traditional Chinese veterinary medicine thinks that this disease is due to water retention in body, spreads unchecked skin, causes with women's head-ornaments, eyelid, four limbs, and even anasarca etc. are the disease of Clinical symptoms.This disease has ailment said due to cold or exposure to attack, and table, sore enemy intrusion or invasion, diseases caused by external factors water are wet, eating and drinking without temperance and insufficiency of natural endowment, prolonged illness overstrain, and the mechanism forming this disease is that lung loses logical tune, and spleen loses and transfers, and kidney loses to be opened entire, and qiactivity of triple energizer is unfavorable.This disease is called in "Nei Jing" " water ", and is divided into geomantic omen, Shi Shui, water burst according to different symptoms." Ling Shu Miraculous Pivot or Divine Axis, water swelling " section has done detailed description to its symptom, as " water has begun also, blepharoedema, and as the shape newly crouched, its neck is pulsed, and time is coughed, cold over the region between the genitalia and thigh, and sufficient shin swells, and abdomen is large, and its water becomes.With hand by its abdomen, rise, ascites as if water being contained within the abdomen conveniently, this its time also." to its pathogenic factor, " a Plain Questions hydro-thermal cave opinion section " is pointed out: " thus the fundamental cause of water disease being in the kidney, the incidental cause of water disease being in the lung." " Plain Questions to very will discuss a section greatly " point out again: " all wet turgors, all belong to spleen." visible in the "Nei Jing" epoch, clearer and more definite understanding be there has been to oedema." Synopsis Golden Chamber " claims this disease for " aqueous vapor ", is divided into geomantic omen, the severe edema due to hypofunction of the spleen, the anasarca with shortness of breath, Shi Shui, yellow sweat five class by the cause of disease, disease.Edema with the heart involved, edema with the lung involved, edema due to dysfunction of the liver, edema with the spleen involved, kidney water is divided into again according to the five internal organs syndrome.Just oedema is divided into yin edema and the large class of yang edema two to Yuan Dynasty's " danxi's experiential therapy oedema ", points out: " if general edema, polydipsia, hot urination, stool closes, and this belongs to yang edema; If " general edema, not polydipsia, large loose stool, oliguria, not puckery red, this belongs to yin edema ".This sorting technique is still significant to instructing clinical syndrome differentiation so far.Ming Dynasty's " Elementary Medicine miscellaneous diseases classification oedema " proposes desolation and can cause oedema, and describe the phenomenon of " running sore is applied ointment; swell more afterwards ", the Qing Dynasty " Zhengzi Huibu oedema " the induction and conclusion therapies of former worthies about oedema, think swollen big method of harnessing the river, and " invigorating the spleen in should adjusting; sthenic splenoqi; self energy lifting runs, then water is wet from removing, and this controls it also.”
According to above-mentioned theory, the invention provides a kind of feed containing the Chinese medicine additive for preventing and treating hydropsy for baby pigs, wherein Chinese medicine additive comprises following raw medicinal material: cape jasmine, Dysosma versipellis, dandelion, Japanese Stephania Root, dindygulen peperomia herb, Radix Isatidis, Chinese violet, Herba Hyperici Patuli, Scirpus tabernaemontani, repent jussiaea herb, fishing rod, water hyacinth root, almond and raphani,radix; Wherein, cape jasmine, Dysosma versipellis, Japanese Stephania Root, dandelion, Herba Hyperici Patuli are clearing heat and detoxicating, inducing diuresis for removing edema, are monarch drug in a prescription, dindygulen peperomia herb, Radix Isatidis, Chinese violet are clearing heat and detoxicating, Scirpus tabernaemontani, repent jussiaea herb, fishing rod inducing diuresis for removing edema, be all ministerial drug in this side, water hyacinth root, almond, raphani,radix freeing lung-Qi and eliminating damp.In addition, the closest internal organs of water liquid metabolism relation are lung, spleen, kidney, the functional disturbance of these three internal organs is the key points causing oedema to occur, therefore preferably, Poria cocos, the bighead atractylodes rhizome, radix fici simplicissimae, breast flower, dried human placenta, the red sage root, arisaema cum bile and oeder plagiopus herb is also comprised in side of the present invention, Poria cocos, the bighead atractylodes rhizome, radix fici simplicissimae invigorating the spleen for eliminating dampness, breast flower, dried human placenta, red sage root temperature kidney, arisaema cum bile, oeder plagiopus herb tranquilizing the mind.Full side organically combines, and complements each other, plays effect that is clearing heat and detoxicating, inducing diuresis for removing edema altogether.
Wherein, the pharmacology of above-mentioned raw materials medicinal material is as follows:
Cape jasmine: bitter, cold.The thoughts of returning home, lung, tri-jiao channel.Function cures mainly: fruit: purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body.Vexed for pyreticosis, jaundice urine is red, blood strangury and dry pain, and blood-head tells nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles; Control bruise pain outward.Root: purging intense heat and detonicating, clearing heat and promoting diuresis, cool the blood dissipate blood stasis.For catarrhal jaundice, traumatic injury, acute toothache.
Dysosma versipellis: sweet, bitter is cool.Function cures mainly: clearing heat and detoxicating, promoting blood circulation and removing blood stasis.Cure mainly: venomous snake bite, traumatic injury; Worm snake bite is controlled in external application, carbuncle sore furuncle, lymphnoditis, mumps, breast cancer.
Dandelion: bitter, sweet, cold.Return liver, stomach warp.Function cures mainly: clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, heat drenches puckery pain.
Japanese Stephania Root: bitter, acrid, cold.Function cures mainly: clearing heat and detoxicating, inducing diuresis to reduce edema, wind-expelling pain-stopping.For abscess of throat, toothache, stomachache, oedema, beriberi, urgent urination odynuria, difficult urination, eczema of vulva, rheumatic arthritis; Traumatic injury is controlled in external application, venomous snake bite, and carbuncle swells sore furuncle.
Dindygulen peperomia herb: pungent; Cool.Return lung; Spleen; Liver; Kidney channel.Function cures mainly: clearing heat and detoxicating; Blood stasis-eliminating and stagnation-dissipating; Inducing diuresis for removing edema.Main lung heat is coughed and is breathed heavily; Measles; Sore; Cancerous swelling; Burn and scald; Traumatic injury; Nephritic dropsy.
Radix Isatidis: bitter, cold.The thoughts of returning home, stomach warp.Function cures mainly: clearing heat and detoxicating, cool blood relieve sore throat.For febrile virulent maculae, tongue is secretly dark reddish purple, mumps, larynx numbness, scarlet fever, major part pestilence, erysipelas, and carbuncle swells.
Chinese violet: another name: arrow grass (" Prescriptions for Universal Relief "), goat's horn (" the secret contain of universe business "), tiger of walking alone (" detailed outline "), Bunge Corydalis Herb (" book on Chinese herbal medicine is new again "), grass of complying with one's wishes (" occupying diet spectrum with breath ").Source: be Violaceae Chinese violet, viola japonica; The whole herb with root of legume Gueldenstaedtia verna, little Gueldenstaedtia verna or gentianaceae plant Gentiana.1. Chinese violet, viola japonica: between 5 ~ August, take whole herb with root during fruit maturation, remove earth, dry.2. Gueldenstaedtia verna and little Gueldenstaedtia verna: spring, autumn excavate whole herb with root, dry or using fresh herb.3. Gentiana: spring, summer, take herb during Hua Chukai, dry.Hardship, cold.Enter the heart, Liver Channel.Function cures mainly: clearing heat and promoting diuresis, removing toxicity for detumescence.Control furunculosis, carbuncle swells, scrofula, jaundice, dysentery, diarrhoea, hot eyes, larynx numbness, venomous snake bite.
Herba Hyperici Patuli: micro-hardship, cold.Function cures mainly: clearing heat and detoxicating, cooling blood and hemostasis, and desinsection is antipruritic.Herb: the infection of the upper respiratory tract, hepatitis, dysentery, ephritis.Really: metrorrhagia, nosebleed epistaxis.Leaf: pruitus is controlled in external application, impetigo.Root: ascarifuge.
Scirpus tabernaemontani: taste is sweet; Light; Property is put down.Return urinary bladder channel.Function cures mainly: inducing diuresis for removing edema.Main oedema turgor; Difficult urination.
Repent jussiaea herb: bitter; Micro-sweet; Cold in nature, function cures mainly: heat-clearing; Diuresis; Removing toxic substances.Main cold, fever; Cough caused by dryness-heat; High hot polydipsia; Drench pain; Oedema; Pharyngalgia; Larynx swells; Aphtha; Acute toothache; Sore carbuncle malignant boil swells; Burn and scald; Fall injure swollen; Poisonous snake; Lyssodexis.
Fishing rod: micro-hardship is cool.Function cures mainly: clearing heat and detoxicating, inducing diuresis for removing edema, blood stasis removing analgesic.For cough with lung heat, hepatitis, oedema; Traumatic injury is controlled in external application, venomous snake bite, burn and scald.
Water hyacinth root: another name: native coltsfoot.Source: medicinal material Ji Yuan: be the root and rhizome of feverfew Adenocaulon himalaicum Edgew Maxim.Latin plant animal mineral name: Adenocaulon himalaicum Edgew. [A.adhaerescens Maxim.; A.bicolor Hook.var .adhaerescens Maki-no] to gather and store: summer, autumn excavate, and clean using fresh herb or dry.Taste is pungent; Bitter; Property is put down.Function cures mainly: freeing lung and relieving asthma; Inducing diuresis for removing edema; Loose stasis of blood pain.Main cough and asthma; Oedema difficult urination; The stagnant stomachache of the stasis of blood in postpartum; Traumatic injury.
Almond: bitter; Temperature; Poisonous.Return lung; Spleen; Large intestine channel.Function cures mainly: expelling phlegm and arresting coughing; Relieving asthma; Ease constipation; Lower gas opens numbness.Main exogenous cough; Breathe heavily full; Cough due to dryness; Cold air is to globefish; Frightened epilepsy; The obstruction of qi in the chest; Dyspeptic stomachache; Metrorrhagia; Deaf; Malnutritional scrotal edema; Damp-heat gonorrhoea; Scabies; Larynx numbness; The dry constipation of intestines.
Raphani,radix: sweet; Pungent; Flat.Return lung; Kidney channel.Function cures mainly: promoting the circulation of qi disappears long-pending, reduces phlegm, and quenches one's thirst, and sharp water Xiao swells.Main coughing with a lot of sputum; Stagnation of QI due to dyspepsia; Abdominal distension ruffian is full; Dysentery; Quench one's thirst; Beriberi, oedema.
Poria cocos: sweet, light is flat.The thoughts of returning home, lung, spleen, kidney channel.Function cures mainly: clearing damp and promoting diuresis, the peaceful heart of invigorating the spleen.For oedema oliguria, phlegm and retained fluid is dizzy throbs with fear, and insufficiency of the spleen food is few, has loose bowels in loose stool, confused and worried, palpitation with fear insomnia.
The bighead atractylodes rhizome: bitter, sweet, temperature.Return spleen, stomach warp.Function cures mainly: strengthening the spleen and replenishing qi, eliminating dampness Li Shui, and hidroschesis is antiabortive.Few for insufficiency of the spleen food, abdominal distension is had loose bowels, and phlegm and retained fluid is dizzy throbs with fear, oedema, spontaneous perspiration, fetal irritability.Rhizoma Atractylodis Macrocephalae invigorating the spleen, and stomach, antiabortive.Few for insufficiency of the spleen food, loose stool of having loose bowels, fetal irritability.
Radix fici simplicissimae: sweet, tepor.Function cures mainly: invigorating the spleen for eliminating dampness, and promoting the circulation of qi is reduced phlegm, and stimulates the circulation of the blood and cause the muscles and joints to relax.For pulmonary tuberculosis cough, chronic bronchitis, rheumatic arthritis, waist has a pain in the leg, insufficiency of the spleen edema, after being ill night sweat, leukorrhea.
Breast flower: another name: parmelia saxatilis; Source: medicinal material Ji Yuan: spatter as flower person for loose on clock emulsion dropstone.Latin plant animal mineral name: Stakactite.Gather and store: gathering in limestone cavern, except impurity elimination stone, cleaning.Sweet; Temperature; Nontoxic.Function cures mainly: warm kidney; Strong bone; Supporing yang.Main muscles and bones impotence is soft; Waist pin crymodynia; Impotence and premature ejaculation.
Dried human placenta: sweet, salty, temperature.The thoughts of returning home, lung, kidney channel.Function cures mainly: warm kidney mends essence, nourishing qi and blood.Thin thin for consumptive disease, hectic fever due to yin night sweat, cough and asthma, food weak breath is short, impotence and seminal emission, infertile few breast.
The red sage root: bitter, is slightly cold.The thoughts of returning home, Liver Channel.Function cures mainly: stasis-dispelling and pain-killing, activating blood to promote menstruation, and clear away heart-fire relieving restlessness.For irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, chest ventral spine pain, hot numbness pain, and sore swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Arisaema cum bile: bitter, micro-pungent, cool.Return lung, liver, the spleen channel.Function cures mainly: clearing heat and eliminating phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, apoplexy phlegm fan, demented frightened epilepsy.
Oeder plagiopus herb: source: Bartramiaceae flat Bartramia plant flat pearl moss Plagiopus oederi (Gunn.) Limpr., with all herbal medicine.The four seasons can adopt, and dry in the shade after expressed water.Light, flat.Function cures mainly: calm peace is frightened.Nervous for having a sleepless night, epilepsy.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine additive
Embodiments providing a kind of Chinese medicine additive for preventing and treating hydropsy for baby pigs, being made up of the raw medicinal material of following parts by weight: cape jasmine 26 weight portion, Dysosma versipellis 17 weight portion, dandelion 21 weight portion, Japanese Stephania Root 15 weight portion, dindygulen peperomia herb 12 weight portion, Radix Isatidis 15 weight portion, Chinese violet 10 weight portion, Herba Hyperici Patuli 14 weight portion, Scirpus tabernaemontani 15 weight portion, repent jussiaea herb 15 weight portion, fishing rod 10 weight portion, water hyacinth root 14 weight portion, almond 17 weight portion and raphani,radix 13 weight portion;
Its preparation method is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 90%, adds hot reflux 2 hours, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 2 times to be again the ethanol of 90%, to add hot reflux 2 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 2 hours, pulverize, sieve, obtain 300 order object micropowders;
3rd step, adds the starch relative to its quality 3 times in the micropowders obtained by second step, mixing, obtains powder.
Embodiment 2 feed
Embodiments provide a kind of feed for preventing and treating hydropsy for baby pigs, feed is made up of the raw material of following parts by weight: corn 48 weight portion, dregs of beans 23 weight portion, broad bean 27 weight portion, red bean 17 weight portion, fish meal 12 weight portion, waxgourd peel 14 weight portion, SDPP 7 weight portion, probiotics 0.3 weight portion, salt 2 weight portion, soybean oil 2 weight portion, microelement pre-mix material 0.02 weight portion, vitamin premix 0.02 weight portion and Chinese medicine additive 5 weight portion.
Wherein, probiotics is bacillus and lactic acid bacteria; Vitamin premix is vitamin A, D3, E, K3, B1, B2, B6, folic acid, pantothenic acid, nicotinic acid; Microelement pre-mix material is copper, iron, manganese, zinc, iodine, selenium.Chinese medicine additive is made up of the raw medicinal material of following parts by weight: cape jasmine 26 weight portion, Dysosma versipellis 17 weight portion, dandelion 21 weight portion, Japanese Stephania Root 15 weight portion, dindygulen peperomia herb 12 weight portion, Radix Isatidis 15 weight portion, Chinese violet 10 weight portion, Herba Hyperici Patuli 14 weight portion, Scirpus tabernaemontani 15 weight portion, repent jussiaea herb 15 weight portion, fishing rod 10 weight portion, water hyacinth root 14 weight portion, almond 17 weight portion, raphani,radix 13 weight portion, Poria cocos 18 weight portion, the bighead atractylodes rhizome 12 weight portion, radix fici simplicissimae 15 weight portion, breast spends 15 weight portions, dried human placenta 12 weight portion, the red sage root 16 weight portion, arisaema cum bile 13 weight portion and oeder plagiopus herb 15 weight portion,
The preparation method of Chinese medicine additive is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 90%, adds hot reflux 2 hours, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 2 times to be again the ethanol of 90%, to add hot reflux 2 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 2 hours, pulverize, sieve, obtain 300 order object micropowders;
3rd step, adds the starch relative to its quality 3 times in the micropowders obtained by second step, mixing, obtains powder.
The preparation method of feed is:
Pulverising step: take corn, dregs of beans, broad bean, red bean, fish meal and waxgourd peel by weight, drops into pulverizer and pulverizes;
Blend step: by weight by after SDPP, salt, soybean oil, microelement pre-mix material, vitamin premix and Chinese medicine additive premixed, more fully mix with the comminuting matter obtained in pulverising step;
Granulation step: drop into granulator, granulates, makes its gelatinization degree reach 90% at 70 DEG C;
Spraying process: the surface by weight percentage probiotics being sprayed to pellet.
Toxicity test
By cape jasmine 26g, Dysosma versipellis 17 g, dandelion 21 g, Japanese Stephania Root 15 g, dindygulen peperomia herb 12 g, Radix Isatidis 15 g, Chinese violet 10 g, Herba Hyperici Patuli 14 g, Scirpus tabernaemontani 15 g, repent jussiaea herb 15 g, fishing rod 10 g, water hyacinth root 14 g, almond 17 g, raphani,radix 13 g, Poria cocos 18g, bighead atractylodes rhizome 12g, radix fici simplicissimae 15g, breast flower 15g, dried human placenta 12g, red sage root 16g, arisaema cum bile 13g and oeder plagiopus herb 15g mixes, be ground into 200 object powder, add the water of 1962g, soak after 30 minutes, decoct 1 hour at the temperature of 100 DEG C, decoction liquor is filtered, obtain the first filtered fluid and filter residue, the filter residue of acquisition is added the water of 1300g, at the temperature of 100 DEG C, decoct 50 minutes, decoction liquor is filtered, obtain the second filtered fluid, first filtered fluid and the second filtered fluid are merged, obtain decoction liquor 1.
Select SD rat 60, divide three groups, often organize 20, give the decocting liquid 1 of the Chinese medicine composition of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive killed 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the changes of weight of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology with drug withdrawal.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and control group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range (NR), without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.
Contrast test
Pig plant of Qingdao city, find that oedema in various degree all appears in 500 bull weanling pigs the end of the year 2013, main based on cephalledema, also there is the symptoms such as ataxia, convulsions, paralysis, rear quarters be unable, there is dead piglet after finding ill several days, after being dissected by dead piglet, find that head is subcutaneous in canescence bean jelly sample oedema, in gel-shaped oedema between the mucous layer and muscle layer of stomach, intestinal mucosa redness is even hemorrhage.
In an aseptic environment, isolate dead piglet stomach edematous fluid and lymphonodi gastrici streak inoculation on maconkey agar flat board, 24h is cultivated under 37 DEG C of conditions, select red median size smooth colony, be inoculated in ordinary broth and increase bacterium, then line on maconkey agar flat board, the single bacterium colony of picking, through smear, dyeing, microscopy, turn out to be gram-Negative bacillus.By purebred inoculation in ordinary nutritional meat soup, be placed in 37 DEG C and cultivate 18h, bacterium liquid first counts roughly by turbidimetry, then doubling dilution, with planar surface rubbing method counting total plate count, then by bacterium liquid diluted for use.
Select sodium selenite 80 as prevention experimental subjects, two groups are divided into immediately after wean, often organize 20, be respectively embodiment group 1, embodiment group 2, control group and blank group, embodiment group 1 is fed after weaning and is mixed with the conventional feed of the embodiment of the present invention 1 powder, the feed of the embodiment of the present invention 2 of feeding after embodiment group 2 wean, control group and blank group are conventionally fed conventional feed, three days laggard row artificial challenges, bacterium liquid for subsequent use is injected the sodium selenite of embodiment group and control group, by aseptic meat soup injection blank group, infect rear three experimental group all to feed conventional feed, observe each experimental group incidence, result is as shown in table 1.
Table 1 each experimental group incidence table of comparisons
From the data of table 1, use the piglet that the conventional feed of powder containing the embodiment of the present invention 1 and the feed of embodiment 2 are fed, its incidence of disease obviously reduces, and namely feed of the present invention has the effect of prevention hydropsy for baby pigs, and has no side effect, Be very effective.
Select wherein to make a definite diagnosis ill piglet 300 as Experiment on therapy object, be divided into three experimental group at random, often organize 100, be respectively embodiment group 1, embodiment group 2 and control group, each experimental group piglet age in days, body weight, the state of an illness etc. are no difference of science of statistics all, has comparativity.Three experimental group adopt the feed of the powder of embodiment 1, embodiment 2 and conventional medicament to treat respectively; Wherein, the powder of embodiment 1 is mixed in conventional feed according to the ratio of weight and number of 3:100, and traditionally feed mode is fed, and feeds 3-7 days continuously; The feed of embodiment 2 is fed according to normal feed mode, continuously treatment 3-7 days; Control group adopts intramuscular injection kanamycin sulfate injection liquid, and every 300,000 IU, parenteral solution 2ml, once a day, be used in conjunction 3-4 time.Treatment results is as shown in table 2.
Table 2 each experimental group treatment results table of comparisons
From the data of table 2, adopt the Chinese medicine additive of embodiment of the present invention 1-2 and feed to hydropsy for baby pigs cure rate apparently higher than control group.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. for preventing the functional feed of hydropsy for baby pigs, it is characterized in that, described feed comprises following raw material: corn, dregs of beans, broad bean, red bean, fish meal, waxgourd peel, SDPP, probiotics, salt, soybean oil, microelement pre-mix material, vitamin premix and Chinese medicine additive.
2. use according to claim 1 is for preventing the functional feed of hydropsy for baby pigs, it is characterized in that, described feed is made up of the raw material of following parts by weight: corn 35-55 weight portion, dregs of beans 18-35 weight portion, broad bean 20-35 weight portion, red bean 15-20 weight portion, fish meal 10-15 weight portion, waxgourd peel 10-18 weight portion, SDPP 5-10 weight portion, probiotics 0.1-0.5 weight portion, salt 1-3 weight portion, soybean oil 1-3 weight portion, microelement pre-mix material 0.01-0.05 weight portion, vitamin premix 0.01-0.05 weight portion and Chinese medicine additive 3-7 weight portion.
3. according to claim 1 and 2 for preventing the functional feed of hydropsy for baby pigs, it is characterized in that, described feed is made up of the raw material of following parts by weight: corn 48 weight portion, dregs of beans 23 weight portion, broad bean 27 weight portion, red bean 17 weight portion, fish meal 12 weight portion, waxgourd peel 14 weight portion, SDPP 7 weight portion, probiotics 0.3 weight portion, salt 2 weight portion, soybean oil 2 weight portion, microelement pre-mix material 0.02 weight portion, vitamin premix 0.02 weight portion and Chinese medicine additive 5 weight portion.
4. the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-3, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: cape jasmine, Dysosma versipellis, dandelion, Japanese Stephania Root, dindygulen peperomia herb, Radix Isatidis, Chinese violet, Herba Hyperici Patuli, Scirpus tabernaemontani, repent jussiaea herb, fishing rod, water hyacinth root, almond and raphani,radix.
5. the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: cape jasmine 20-30 weight portion, Dysosma versipellis 12-21 weight portion, dandelion 15-30 weight portion, Japanese Stephania Root 10-19 weight portion, dindygulen peperomia herb 8-15 weight portion, Radix Isatidis 10-20 weight portion, Chinese violet 5-15 weight portion, Herba Hyperici Patuli 8-17 weight portion, Scirpus tabernaemontani 9-21 weight portion, repent jussiaea herb 8-20 weight portion, fishing rod 5-15 weight portion, water hyacinth root 10-20 weight portion, almond 10-20 weight portion and raphani,radix 10-15 weight portion.
6. the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-5, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: cape jasmine 26 weight portion, Dysosma versipellis 17 weight portion, dandelion 21 weight portion, Japanese Stephania Root 15 weight portion, dindygulen peperomia herb 12 weight portion, Radix Isatidis 15 weight portion, Chinese violet 10 weight portion, Herba Hyperici Patuli 14 weight portion, Scirpus tabernaemontani 15 weight portion, repent jussiaea herb 15 weight portion, fishing rod 10 weight portion, water hyacinth root 14 weight portion, almond 17 weight portion and raphani,radix 13 weight portion.
7. the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-6, is characterized in that, described Chinese medicine additive also comprises Poria cocos, the bighead atractylodes rhizome, radix fici simplicissimae, breast flower, dried human placenta, the red sage root, arisaema cum bile and oeder plagiopus herb, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: cape jasmine 20-30 weight portion, Dysosma versipellis 12-21 weight portion, dandelion 15-30 weight portion, Japanese Stephania Root 10-19 weight portion, dindygulen peperomia herb 8-15 weight portion, Radix Isatidis 10-20 weight portion, Chinese violet 5-15 weight portion, Herba Hyperici Patuli 8-17 weight portion, Scirpus tabernaemontani 9-21 weight portion, repent jussiaea herb 8-20 weight portion, fishing rod 5-15 weight portion, water hyacinth root 10-20 weight portion, almond 10-20 weight portion, raphani,radix 10-15 weight portion, Poria cocos 10-25 weight portion, bighead atractylodes rhizome 10-15 weight portion, radix fici simplicissimae 10-20 weight portion, breast flower 10-20 weight portion, dried human placenta 10-15 weight portion, red sage root 10-22 weight portion, arisaema cum bile 10-15 weight portion and oeder plagiopus herb 10-20 weight portion.
8. the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-7, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: cape jasmine 26 weight portion, Dysosma versipellis 17 weight portion, dandelion 21 weight portion, Japanese Stephania Root 15 weight portion, dindygulen peperomia herb 12 weight portion, Radix Isatidis 15 weight portion, Chinese violet 10 weight portion, Herba Hyperici Patuli 14 weight portion, Scirpus tabernaemontani 15 weight portion, repent jussiaea herb 15 weight portion, fishing rod 10 weight portion, water hyacinth root 14 weight portion, almond 17 weight portion, raphani,radix 13 weight portion, Poria cocos 18 weight portion, the bighead atractylodes rhizome 12 weight portion, radix fici simplicissimae 15 weight portion, breast spends 15 weight portions, dried human placenta 12 weight portion, the red sage root 16 weight portion, arisaema cum bile 13 weight portion and oeder plagiopus herb 15 weight portion.
9. the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-8, is characterized in that, the preparation method of described Chinese medicine additive is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds the starch relative to its quality 2 ~ 4 times in the micropowders obtained by second step, mixing, obtains powder.
10. the preparation method of the functional feed for preventing hydropsy for baby pigs according to any one of claim 1-9, is characterized in that, the preparation method of described feed is:
Pulverising step: take corn, dregs of beans, broad bean, red bean, fish meal and waxgourd peel by weight, drops into pulverizer and pulverizes;
Blend step: by weight by after SDPP, salt, soybean oil, microelement pre-mix material, vitamin premix and Chinese medicine additive premixed, more fully mix with the comminuting matter obtained in pulverising step;
Granulation step: drop into granulator, granulates, makes its gelatinization degree reach 90% at 70-80 DEG C;
Spraying process: the surface by weight percentage probiotics being sprayed to pellet.
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| CN108835411A (en) * | 2018-06-25 | 2018-11-20 | 江西成必信生物科技有限公司 | One boar compound Chinese medicine feed addictive |
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Application publication date: 20150408 |