CN104470572B - Paediatrics full facepiece mask - Google Patents
Paediatrics full facepiece mask Download PDFInfo
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- CN104470572B CN104470572B CN201380036685.9A CN201380036685A CN104470572B CN 104470572 B CN104470572 B CN 104470572B CN 201380036685 A CN201380036685 A CN 201380036685A CN 104470572 B CN104470572 B CN 104470572B
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- opening
- pediatric patients
- shield assembly
- face shield
- helmet
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- 238000007789 sealing Methods 0.000 claims abstract description 34
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 6
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- 230000029058 respiratory gaseous exchange Effects 0.000 description 42
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- 239000000463 material Substances 0.000 description 15
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- 238000010276 construction Methods 0.000 description 5
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- 206010021079 Hypopnoea Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 206010041235 Snoring Diseases 0.000 description 1
- KFVPJMZRRXCXAO-UHFFFAOYSA-N [He].[O] Chemical compound [He].[O] KFVPJMZRRXCXAO-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
- A61M16/0605—Means for improving the adaptation of the mask to the patient
- A61M16/0627—Means for improving the adaptation of the mask to the patient with sealing means on a part of the body other than the face, e.g. helmets, hoods or domes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
- A61M16/0683—Holding devices therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
- A61M16/0825—Joints or connectors with ball-sockets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
- A61M16/0841—Joints or connectors for sampling
- A61M16/0858—Pressure sampling ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
- A61M16/0605—Means for improving the adaptation of the mask to the patient
- A61M16/0616—Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
- A61M16/208—Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
Abstract
It is a kind of to be used to being transported to stream of therapeutic gas into the face shield assembly (10) that uses in the system of pediatric patients air flue.The face shield assembly is included with the mask body (12) for being suitable to the opening (13) for receiving treatment gas supply, and flexible periphery sealing structure (20).The flexible periphery sealing structure (20) has the first side and the second opposite side, first side is connected to the mask body, and second side includes opening, the opening is suitable to the face for receiving the pediatric patients so that engage to second side seal circumference of the pediatric patients face.The opening is by height (HI) and width (WI) limit.The ratio of the height and the width of the opening is about 0.83.
Description
The cross reference of related application
The U.S. Provisional Application case that present application for patent was submitted according to 35U.S.C. § 119 (e) requirements on June 7th, 2012
The senior interest of the 61/656th, No. 737, the content of the U.S. Provisional Application case is incorporated herein by reference.
Invention field
The present invention relates to therapeutic gas induction system, and more particularly to one kind gas convey during with paediatrics
Patient facial region forms sealed mask.
Background technology
In many cases, it is necessary to or expect breathing gas stream being non-invasively delivered to patient airway, that is, it is not necessarily
Trachea cannula is inserted into its esophagus by patient cannula by surgical operation.For example, as it is known that logical using referred to as non-intrusion type
The technology of gas (NIV) is come for patient ventilation.It it is known that (it is with trouble for conveying continuous positive airway pressure (CPAP) or variable airway pressure
Respiratory cycle of person and change) treat medical conditions, such as sleep apnea syndrome, especially obstructive sleep
Sleep apnea (OSA), chronic obstructive disease of lung (COPD) or congestive heart failure (CHF).
Non-invasive ventilation and pressure support therapy are related to patient interface device, typically nose cup or nasal oral mask (i.e.,
Full facepiece mask), be placed on patient facial region, lung ventilator or pressure support system are interfaced with the air flue of patient together with so that
Breathing gas stream can be transported to the air flue of patient from pressure/gas air flow-producing device.
One class respiratory face shield assembly can have two kinds of different types:Earthed circuit type and two-wire circuit type.For list
For line loop, face shield assembly generally comprises valve and exhaust outlet, and for two-wire circuit, face shield assembly does not include valve generally
But no valve pipeline is provided on the contrary.Other types of mask can also be conducive to different applications.Therefore, hospital and other guarantors
Strong mechanism generally lays in several different types of face shield assemblies, and the face shield assembly can be used for different applications.It is several with laying in
The associated cost of different face shield assemblies and memory space consider it can is important.
Hospital is pediatric patients generally not for its specific crowd for laying in dedicated facemask.Mask is not laid in for such patient
One reason is small demand.Larger the reason for, is a lack of the mask available for pediatric patients, especially for such patient
For middle minimum patient.
Accordingly, it would be desirable to a kind of improve the patient interface component of existing component, for example, with by Positive Airway Pressure or gas stream
Patient comfort is maximized during being delivered to pediatric patients air flue, while minimizing leakage.
The content of the invention
As one aspect of the present invention, there is provided a kind of system for stream of therapeutic gas to be transported to pediatric patients air flue
Used in face shield assembly.The face shield assembly includes:Mask body, the mask body, which has, to be suitable to receive treatment gas
The opening of supply;And the flexible periphery sealing structure with the first side and the second opposite side, first side is attached to institute
Mask body is stated, second side includes opening, and the opening is suitable to receive the pediatric patients face so that second side
Sealingly engage the circumference (perimeter) of the pediatric patients face.The opening is limited by height and width, and described is opened
The ratio of the height and the width of mouth is in the range of about 0.83 to about 0.87.In one embodiment, the opening can have
There are about 60.5mm height and about 73mm width.
The paediatrics face shield assembly can also include the helmet component for being selectively coupled to the mask body.The head
Helmet component can include the helmet component of bonnet (bonnet) pattern.The helmet component can have instruction to be intended to use the group
The color of the sex of the pediatric patients of part.The helmet component can be one below:Blue color, to indicate that male's paediatrics is suffered from
Person;Or pink tone, to indicate female patient.
There is provided a kind of it is used to that the system that gas is transported to pediatric patients air flue will to be treated as another aspect of the present invention.
The system includes:Pressure/air-flow generation system;Tubing element with first end and the second opposite end, the first end
It is connected to the pressure/air-flow generation system;Face shield assembly as previously discussed;And optionally it is attached to the mask master
The helmet component of body.
As another aspect of the present invention, there is provided a kind of external member.The external member includes:Face shield assembly as discussed previously;
And multiple helmet components, each helmet component is optionally attached to the face shield assembly.At least one helmet component bag
The color for being suitable to indicate that male patient is included, and at least another helmet component includes being suitable to indicate that the color of female patient.
After refer to the attached drawing considers following description and appended claims, these and other mesh of the invention
, feature and feature and the operating method and function of structure related elements and component combination, the economy of manufacture will become more
Plus it is clear that all these descriptions and claims and drawing form the part of this specification, wherein, similar member
Part symbol indicates the appropriate section in different accompanying drawings.However, being clearly understood that, these accompanying drawings are merely for illustration and describe
Purpose, it is no intended to be used as the restriction of limitation of the present invention.
Brief description of the drawings
Figure 1A is the saturating of the system that embodiments in accordance with the present invention include the face shield assembly being arranged on pediatric patients face
View;
Figure 1B is Figure 1A system and the left side perspective view of face shield assembly;
Fig. 2 is the perspective view of Figure 1A and 1B face shield assembly, and the face shield assembly is attached to according to embodiments of the present invention
Volume inhales (entrainment) valve module;
Fig. 3 is the decomposition diagram of face shield assembly according to embodiments of the present invention;
Fig. 4 is the perspective view of the Air Entrainment valve with exhaust outlet component according to embodiments of the present invention;
Fig. 5 is another perspective view of the Air Entrainment valve with the exhaust outlet component shown in Fig. 4;
Fig. 6 is the sectional view of face shield assembly shown in Fig. 2;
Fig. 7 is that the volume of face shield assembly shown in Fig. 2 inhales valve module and the sectional view at breathing circuit interface;
Fig. 8 is the front view of the patient-side of face shield assembly shown in Fig. 2;And
Fig. 9 is the perspective view of the bottom patient-side of face shield assembly shown in Fig. 2.
Embodiment
Unless expressly stated otherwise, otherwise " one " of singulative used herein, " one " and "the" include it is multiple
Number implication.The statement of two or more parts used herein or part " connection " refers to these parts directly or indirectly (i.e.
By one or more center sections or part) it is combined together or operates together, as long as occurring linking.It is used herein
" directly connection " refer to that two elements are mutually directly contacted." regularly coupling " used herein or " fixation " refer to two
Individual part connection keeps constant orientation relative to each other in the movement as one.Phrase used herein two or
More elements " optionally coupling " element should be referred to can be easily located at coupled or non-coupled position in
Mode is connected.
Word " single " used herein is that finger is produced as single-piece or unit.That is, produced including separated
Then it is not " single " part or main body to be linked together as the part of multiple of a unit.Used herein
The statement of two or more parts or part mutually " engagement " refers to that these parts direct or through one or more pars intermedias
Divide or part mutually exerts on power.Term " quantity " used herein refers to one or the integer (i.e. multiple) more than one.
The mask embodiment designed according to the present invention is designed specifically for the certain surface from birth to the child of 18 months
Portion's shapes/configurations, therefore phrase " pediatric patients " should refer to 18 months big or smaller patient.Such child is typically shown as having
Following face shape/structure:With the vertical facial dimension and the ratio of width between about 0.83 to about 0.87.This
Typical child/adult face's shapes/configurations that the ratio that class face shape/structure is different from height and the width is 1.0.Therefore,
Traditional full facepiece mask applicable to children and adult will not work to the pediatric patients desired by the embodiment of the present invention.
Unless expressly stated otherwise, otherwise directionality phrase used herein, such as, but not limited to, top, bottom
, the left side, the right, top, bottom, above, below and their derivative be related to what is shown in figure
The orientation of element, and it is not intended to limit claims.
Figure 1A, 1B and 2-9 show it is according to embodiments of the present invention be used for face shield assembly 10 that therapeutic gas conveys and
Associated components.Referring to Figure 1A, 1B, 2 and 3, face shield assembly 10 can be generally included with for receiving opening for breathing gas supply
The mask body 12 of mouth 13.Mask body 12 includes the facial sealing structure for being used for sealingly engaging pediatric patients 27 (Figure 1A)
20, with surrounding relationship at least with the nose and mouth of pediatric patients 27 (and alternatively, eye) shape.As shown in fig. 6, mask
Component 10 has total depth D in the region that the temple with pediatric patients are substantially consistent in outer edgeT, and due to sealing knot
The general curved shape of structure 20 and be less than total depth DTCentral depth level DC, as may be best shown in Fig. 9.In example
Property embodiment in, face shield assembly 10 have about 67mm total depth DT, and about 48mm central depth level DC。
In one embodiment, face shield assembly 10 also includes breathing circuit interface 16, for connecting mask body 12 with adding
Press breathing gas supply.Following article is disclosed more closely in, and breathing circuit interface 16 has:It is rotatably attached with mask body 12
Part I 17;And Part II 19, the Part II is structured and is arranged to be connected with pipeline 18, for that will exhale
The supply of air-breathing body is transported to pediatric patients 27 by opening 13.
In the exemplary embodiment, breathing circuit interface 16 and pipeline 18 connect mask body 12 via loop tubing 40
(schematically shown in figs. 1 a and 1b) to pressure/air-flow generation system 42, for example lung ventilator, CPAP device or variable pressure
Device, such as by Pittsburgh, Pa. Philips Respironics, what Inc. was manufactured and distributedPositive pressure therapy
Device, or automatic Titration pressure support system.Such element combination is commonly referred to as used to treatment gas being conveyed to patient's
" system ".
BiPAP devices are double horizontal devices, wherein being supplied to the pressure of patient to change with the respiratory cycle of patient, are made
Obtain in intake period than conveying higher pressure during exhaling.Automatic Titration pressure support system is wherein pressure with patient
Situation and the system that changes, the situation, which is, for example, the patient, is snoring or is undergoing respiratory disorder or hypopnea.Go out
In current purpose, pressure/air-flow generation system 42 is also referred to as gas stream generation apparatus, because can be produced when producing barometric gradient
Angry body stream.It is envisioned that, pressure/air-flow generation system 42 is to be used to gas stream is transported into patient airway or is used for
Any traditional system of lift gas pressure, includes the pressure support system and non-intrusion type of above-outlined at patient airway
Aerating system.
As will be evident that the Part II 19 at breathing circuit interface 16 is releasedly according to herein further illustrating
Connecting pipe 18, to cause different types of pipeline 18 to may be connected to mask body 12.Accordingly, it will be recognized that different from herein
The other pipelines for those pipelines being described in detail can also be used for mask body 12, without changing the scope of the present invention.In addition, exhaling
The rotatable or rotation connection at the Part I 17 of loopback interface 16 between breathing circuit interface 16 and mask body 12 is inhaled to permit
Perhaps elbow pipeline 18 rotates after connection, with pipeline 18 is extended in either direction in 360 ° of rotation so as to tubing
40 connections.It should be appreciated that for some purposes, breathing circuit interface 16 can also be considered as a part for mask body 12.
As shown in figure 3, breathing circuit interface 16 has loop configurations, wherein general cylindrical inner surface 23 is arranged at center
It is open around (being generally illustrated at such as 29).As basis is discussed in greater detail it will be recognized that the cylinder at breathing circuit interface 16 later
Shape inner surface 23 is shaped and configured into the releasable friction provided with the general cylindrical mating surface 25 of appropriate pipeline 18 and matched somebody with somebody
Close, the pipeline receives the tubing 40 of breathable gas to be connected with being used for.
In the exemplary embodiment, such as shown in Fig. 3, breathing circuit interface 16 extends radially outwardly comprising multiple
Rib 31, the rib is (unnumbered) spaced apart around its outer surface with the periphery interval of rule.In rib 31 each have with
It and extend to Part I 17 and gradually increased thickness or radial dimension from the Part II 19 at breathing circuit interface 16.Rib
31 are integrally molded so as a part for the outer surface at breathing circuit interface 16.Positioned at breathing circuit interface 16 Part II 19 it is outer
Multiple ribs 31 on surface provide crawl section for nursing staff, so as to by pipeline 18 be connected to breathing circuit interface 16 and
Breathing circuit interface 16 is kept when being disconnected from it.Rib 31 is also beneficial to the manual rotation at breathing circuit interface 16.It is contemplated by the invention that
Arrive, any technology for breathing circuit to be connected to mask body can be used in face shield assembly 10.
In one exemplary embodiment, mask body 12 includes the rigid element 21 formed by transparent plastic material, with
And foregoing flexible periphery sealing structure 20.Flexible periphery sealing structure 20 is attached to the rigid element 21 weeks of mask body 12
Enclose.
In one exemplary embodiment, for example shown in Figure 1A and 1B, mask body 12 is suitable to be connected with helmet component 11,
The helmet component can be used for being arranged on mask body 12 on the head of pediatric patients 27.In the exemplary embodiment, a pair
Helmet attachment intermediate plate 14 is provided for joining and being connected with the bottom helmet mounting bar band part 44 of helmet component 11.A pair of helmets
Attachment members 22 (Fig. 3) are provided for joinably receiving the helmet to be attached intermediate plate 14, and a pair of top helmet bands spaced apart
Tab 24 (each, which has, runs through its elongated open 50) is kept to be provided for receiving the top helmet of helmet component 11
Strip portion 46 is installed.This pair of helmet holding tab 24 is arranged at the opposite side on the top of the rigid element 21 of mask body 12
On.This pair of helmet attachment members 22 are arranged in the opposite side of the bottom of the rigid element 21 of mask body 12.Each head
Helmet keeps tab 24 to be integrally formed with rigid element 21, and stretches out from flexible periphery sealing structure 20, in such as Fig. 2 and 3
It is best visible.
In the exemplary embodiment, face shield assembly 10 is characterised by, mask body 12 has 20.27 grams of weight (g), close
Seal structure 20 has weight 33.72g, and face shield assembly 10 and breathing circuit interface 16 and elbow have weight (no helmet)
98.24g, and the face shield assembly 10 with the helmet has weight 124.10g.
Fig. 4 shows the pipeline 18 according to one embodiment.In this embodiment, pipeline 18 is that volume inhales valve module 200.Volume
The substantially elbow tubular element 201 that valve module 200 includes being formed by rigid plastic material is inhaled, such as makrolon or this area
Other plastic materials that technical staff will be recognized that.In one exemplary embodiment, tubular element 201 by clear, colorless modeling
Material material is formed.In a further exemplary embodiment, tubular element 201 is formed by orange/amber material, however, can be not
The component of other colors and/or opacity is used on the premise of changing the scope of the present invention.Tubular element 201 includes main-inlet
202nd, secondary entrance 204 and outlet 206.
Tubular element 201 includes the first connector part 230 and the second connector part 232.First connector part 230
It is general cylindrical with the second connector part 232, and is substantially arranged perpendicular to each other.The He of first connector part 230
Second connector part 232 is engaged by the tubular area 233 of bending.First connector part 230 have it is foregoing substantially
Cylindrical outer surface 25, for being connected with breathing circuit interface 16, and the second connector part 232 also has cylindrical outer surface
205, for the inner surface frictional fit with tubing 40, the tubing is used to receive adding from pressure/air-flow generation system 42
Calm the anger body.
The secondary entrance 204 that volume inhales valve module 200 includes the opening 254 positioned towards the tubular area 233 of bending.Opening
254 are divided into two equal substantially semi-cylindrical sections by flat wall 256.The flat wall 256 that volume inhales valve module 200 is extended through
Cross cylinder open 254.Opening 254 allows in the absence of the energy of pediatric patients 27 when providing to gas-pressurized stream in entrance 202
Reach from air air-breathing or breathe out to air.At cylindrical surface 25, volume inhales valve module 200 and also includes multiple expiration grooves 258.
Groove 258 is located therein volume and inhales the interface that valve module 200 is connected with breathing circuit interface 16.Multiple expiration grooves 258 around
Periphery is spaced apart on surface 25, and is symmetrically disposed on the either side of the first connector part 230.It is contemplated that going out other show
Example property embodiment, wherein expiration groove 258 are located at any position on the outer surface of the first connector part 230, wherein described
Outer surface joins with breathing circuit interface 16.
Expiration groove 258 is fully long so that when promoting volume to inhale valve module 200 as far as possible, it can be entered
In breathing circuit interface 16 (such as shown in Figure 1A, 1B and 2), groove 258 also stretches out from breathing circuit interface 16, and provides
Gas for allowing to breathe out from pediatric patients passes through the path that groove 258 leaves.In addition, for appointing between surface 23 and 25
For what frictional fit degree of engagement, the gap or the sectional area at interval provided by groove 258 will be constant so that expiratory air
The path that body is flowed to outside mask body 12 provides constant resistance, and it is to be completely inserted into breathe back to inhale valve module 200 with volume
Insert less unrelated in road interface 16 or compared with fully-inserted.
Referring to Fig. 3 and 5, volume inhales valve module 200 and includes pressure port 260, and it inhales the bent tube form area of valve module 200 from volume
Domain 233 extends, and is in substantially parallel relationship to the second connector part 232 that volume inhales valve module 200.Dismountable block 262 is used to seal
Close pressure port 260.Block 262 includes crawl tab 264, to aid in dismantling block 262 from pressure port 260.Probe tube is (not
Show) it can be arranged to connect with the gaseous fluid in tubular body 201 via pressure port 260.Sensor (not shown) can
The probe tube is fixed to together with processor, the processor is connected with the sensor.The processor is using coming from
At least one respiration parameter of the signal of change of sensor.The pressure that such arrangement is generally used for measuring lung ventilator feeds back as control
It is supplied to lung ventilator.
As shown in Figures 6 and 7, breathing circuit interface 16 includes foregoing Part I 17 and Part II 19.Part I
17 be substantial circular, and includes the flat wall 408 of annular, and the annular flat wall engages footpath with slidable surface relationships
To the flange portion 70 extended internally.Opening 13 of the flange portion 70 in the rigid element 21 of mask body 12 (see Fig. 3).
The Part I 17 at breathing circuit interface 16 also includes the projection 409 of general cylindrical, its radial direction from annular surface 408
Innermost part stretches out.Cylindrical projection 409 is extended in the opening 13 in the rigid element 21 of mask body 12.
Cylindrical projection 409 includes the groove 410 in cylindrical surface outside (see Fig. 7).Groove 410 accommodates connection gasket
Piece or bearing 412.In one embodiment, pad 412 is flow splitter gasket construction, and it has against the inner surface of flange 70
Neighboring, and the inner rim being received in groove 410, to be rotatably attached breathing circuit interface 16 and mask body
12.Therefore, breathing circuit interface 16 and the rigid element 21 of mask body 12 are rotatably attached.In one embodiment, may be used
Slight friction at rotary interface provide at least the resistance to rotation so that the rotation position at breathing circuit interface 16 can be regarded
Need setting, and it will keep the position manually so that the branch pipe being connected with tubing 40 or the second connector portion of pipeline 18
Divide 232 can be positioned along desired direction, the direction generally maintains constant, unless intentionally changed.In another embodiment
In, the friction at the point of rotation can be minimum, to allow rotating freely for breathing circuit interface 16.
In another embodiment, the connection between the rigid element 21 of breathing circuit interface 16 and mask body 12 can lead to
Cross using ball bearing construction or the bearing construction of any other type to realize, the bearing construction allows breathing circuit interface 16
Relative to the rotary motion of mask body 12.
As discussed above, the inner surface 23 at breathing circuit interface 16 is shaped and configured into removable by frictional fit
Engage the outer surface 25 that volume inhales valve module 200 with unloading.In addition to allowing to inhale the frictional fit of valve module 200 with volume, breathing circuit
The inner surface 23 at interface 16 also allow remove volume inhale valve module 200 and by similar frictional fit from different other types
The interchangeably frictional fit of pipeline 18, as described in more detail below.In the exemplary embodiment, volume inhales valve module 200
The diameter of first connector part 230 is more than the diameter of the second connector part 232, to avoid the wrong end of valve module 200
It is connected to interface 16.
With continued reference to Fig. 6 and 7 sectional view, volume inhales valve module 200 and includes valve member 208.By being arranged at valve member 208
In groove 250, barb 526 and stopper element 528, valve member 208 is connected at the join domain 248 of tubular element 201
Tubular element.The rib 252 (Fig. 7) being positioned on the low portion in the bent tube form region 233 that volume inhales valve module 200, which has, to be received
Outer surface in groove 250, to be clamped and connected region 248 against annular region 253.
Valve member 208 includes hermetic unit 520, and the flattened oval that the hermetic unit has relative thin is configured.Hermetic unit
520 are fabricated from a flexible material, and therefore, it is possible to be bent upwards (such as Fig. 7 in response to gas-pressurized is urged in main-inlet 202
In dotted line shown in).Described be bent upwards is continued until that the upper surface 522 of hermetic unit 520 engages the end of cylindrical wall 254
Untill the annular lip 235 at place, the cylindrical wall is protruding in tubular body 201 and limits time entrance 204.Hermetic unit
520 direct of travel from its resting position to upper curvatures is shown by the arrow A in Fig. 7.In this upper curvatures
In, the upper surface 522 of valve member 208 and the sealing engagement of annular lip 235 cause time entrance 204 to be sealed so that provide extremely
Gas-pressurized in main-inlet 202 will not be escaped by secondary entrance 204.
It should be noted that be not through main-inlet 202 provide gas to pediatric patients in the case of (for example, with
Pressure/air-flow generation system 42 that main-inlet 202 is connected is not operated), secondary entrance 204 can be used as being supplied in intake period
The access road of the atmospheric air of section patient and the exit passageway during exhaling.In the example present, hermetic unit 520 can
It is held in its static position, the upper surface 259 of wherein itself and annular flange 253, which is formed, to be sealed, as shown in Figure 7.
Valve member 208 can be made up of rubber, latex, silicones or any other elastomeric material, such as those skilled in the art
It will be recognized that.
Such as can more easily it be recognized according to Fig. 2 and 4, expiration groove 258 is in the outer surface 25 of tubular portion 201 and breathing
Passage is formd between the inner cylindrical surface 23 of loopback interface 16.In one embodiment, expiration groove 258 is arranged at pipe
On the opposite cross side of the outer surface 25 of shape part 201.In another embodiment, expiration groove can be arranged at breathing circuit
On the inner surface 23 at interface 16, rather than in main body 201.In addition, as shown by a dashed line in fig 7, in another embodiment, as
Another option, or in addition, it can also be positioned at the top office of the outer surface 25 of main body 201.Suffer from paediatrics
During person's air-breathing, the gas of considerably less share can be drawn from air by expiration groove 258.However, on the whole apparently, quilt
It is forced to the pressure that the gas-pressurized in main-inlet 202 will form superatmospheric power in main body 201 so that or even in air-breathing
Period air is also largely forced through exhalation passages 258 outwards (rather than inside).In addition, as pediatric patients are exhaled, being exhaled
The gas impact gone out passes through main body 201 to the incoming air-flow in center, and is therefore forced outwardly radially rapid growth, results in
The circular air-flow pattern of exhaled gas is effectively washed away, and is therefore directed generally towards the expiration groove 258 on periphery and is exhaled described in
Channeling groove is into air.
Detachable and interchangeable pipeline 18 enables face shield assembly 10 to be used only by using selected pipeline 18
In different purposes.While shown as the pipeline 18 that valve module 200 is inhaled suitable for accommodating volume, it should be recognized that it is contemplated by the invention that
To can without altering the scope of the present invention for face shield assembly 10 use other pipelines 18.Can be with above-mentioned face shield assembly 10
Some non-limiting examples for the other type of conduits 18 being interchangeably used together are included:Pipe with bronchoscope port
Road, to allow care-giver to perform bronchoscopy procedure in the case where patient wears mask;Match somebody with somebody with spray generator
The pipeline of fitting, to convey medicine during NIV;Pipeline with MDI ports, to use " metered dose inhaler " conveying medicine;
Pipeline with the port for accommodating CPAP safety valves (relief valve);With CO2Sensor ability is to monitor paediatrics
The pipeline of patient;With measurement CO2The sensor ability of volume is to monitor the VCO of pediatric patients2Pipeline;Carry the mixing of helium oxygen secretly
The pipeline of gas or other special gases;Moisture is added to the pipeline of suction gas;Include the pipe of HME (hot moisture exchanger)
Road;Include " nanometer " sensor to realize the pipeline of various clinical monitoring capability;Pipeline with filtering type expiration function, this
It is very useful in the case of similar SARS pandemic disease;Strengthen the pipe of the ability of patient's " being talked in the case where wearing mask "
Road;Accommodate the pipeline of NG supply pipes;Reduction/control CO2The pipeline of re-breathing;Aid in the pipeline of secretion clearing;With standard
The pipeline of elbow;Available for the pipeline of a variety of mask types, such as complete (nasal oral) cover, only nose cup, nasal intubation, bolster or complete
Mask or the helmet (Helmet) type mask.
It should be appreciated that the pipe of the pipeline configuration provides listed above different type that can be provided, configuration and/or construction
The non-limiting examples in road.It will be appreciated that though these pipelines can be provided with elbow tubular body, but alternatively
Selection, can also provide other tubular forms (such as straight tubular configuration).
It is susceptible to according to other embodiments of the invention, the wherein connection between pipeline 18 and breathing circuit interface 16 not
Frictional fit, and can be by other types of connection to realize, such as connection of (but not limiting) right-angled bend type, buckle
Coordinate or any other locking mechanism being detachably connected between pipeline 18 and breathing circuit interface 16 is provided.
In another embodiment, the first connector part 230 of pipeline 18 itself can be provided with to be similar to and breathe back
The rotation connector at road interface 16, rather than by this structure setting be mask a part.In the case, the rotation connection of elbow
The non-rotating part for the opening 13 that fitting can be directly connected in the rigid element 21 of mask body 12 is (for example, outwards
Prominent cylindrical configuration).
In another embodiment, any rotation connector is not provided.But, in tubular body (for example, 201) and mask
There is provided and be directly connected between the corresponding shaped portion of rigid element 21.In this embodiment, however rigid element 21 can be passed through
The direct sliding friction of frictional fit junction between tubular body come adapt to pipeline 18 some rotation.However, also setting
Expect, other non-rotatable connections can also be provided, and it will still realize the modularization for the design contemplated herein.
There is provided a kind of face shield assembly external member in one aspect of the invention.The dial bundle LMS is included:With or without
The mask body 12 at rotatable interface 16;And different types of at least two pipeline 18, to cause mask body 12 only to pass through
Difference in functionality can be provided by changing conduit types.For example, standard (valveless) elbow can be configured to a pipeline, and volume is inhaled
Valve module 200 can be configured to another pipeline.More than two pipelines can be provided, and more than one face can be provided
Cover, but each in the mask is by with common configuration, and the pipeline is by with coordinating the mask body extremely
Few two different configurations.In addition, the embodiment of the external member includes multiple helmet components 11, wherein at least one helmet component is
The color of male's pediatric patients is indicated, and another helmet component is the color for indicating female patient, following article is discussed in more detail
State.
Referring to Fig. 6,8 and 9, the details of flexible periphery sealing structure 20 will be discussed now.It is best visible in such as Fig. 6, it is soft
Property the section can with general rectangular channel shape of perimeter seal 20 configure, it has three sides 504,506 and
508.Flexible periphery sealing structure 20 can be attached to mask body 12 at side 504.The rigid element 21 of mask body 12
Edge 500 engage the opening 502 that is positioned in the side 504 of flexible periphery sealing structure 20 so that form layering connection.So
The part is adhered to by bonding the suitable connection of connection, ultrasonic bonding connection, riveting, pin joint or any other type afterwards
In place, as skilled in the art will recognize.Other embodiments are also contemplated, wherein in the absence of any overlapping, such as
By rigid element 21 and flexible periphery sealing structure 20 being attached end-to-end with its edge (for example, being connected by bonding).
506 are located between side 504 and side 508 sideways, so as to provide gap between side 504 and 508.This gap can be flexibility
Perimeter seal 20 provides flexibility, because it conforms to the face of pediatric patients 27.The corner of flexible periphery sealing structure 20
It can be substantially cavetto.508 and 506 length can change along the periphery of sealing structure 20 sideways, to provide mask
Main body 12 and the conformal sealing engagement of the face of pediatric patients 27.
More specifically, as shown in Fig. 8 front elevation, the side 508 of perimeter seal 20 has substantially overall height HO
With overall width WO, and comprising the opening generally indicated that at 510, the opening is particularly suited for the face of pediatric patients being received in
Wherein, and it is consequently adapted to sealingly engage the faces of pediatric patients 27 for the perimeter that side 508 is provided in patient facial region
Portion.In order to realize that this coordinates, opening 510 is sized to have and the specific proportional height H of pediatric patients faceIWith
Width WI.Sideways 508 by be generally designed to cause at least opening 510 and side 508 outward flange between midpoints or
Nearby, the face around pediatric patients forms sealing.Substantially height and the width of this minimum sealing area are in fig. 8 respectively by chi
Very little HMAnd WMShow.
In the exemplary embodiment, compared with typical ratios (about 1.0) necessary to adapting to adult patient face, height HI
With width WIRatio be about 0.83.In other embodiments, height HIWith width WIRatio between about 0.83 to about 0.87
In the range of.In the exemplary embodiment, opening 510 has about 60.5mm height HIAbout 73.0mm width WI, and it is therefore high
The ratio of degree and width is about 0.83.In same exemplary embodiment, side 508 also has about 87.9mm overall height HO,
About 100.5mm overall width, and intermediate sizes HM、WMRespectively 74.8mm and 86.9mm.
In the exemplary embodiment, the size of mask is stamped on the end portion of flexible periphery sealing structure 20, in such as 9
600 shown in.
Flexible periphery sealing structure 20 can be made up of the material of flexible relative and/or flexibility so that flexible periphery is sealed
Structure 20 conforms to its shape when being located against pediatric patients face holding.In the exemplary embodiment, using with 20 hardness
Material (compared with 40 hardened materials generally used in the application of adult).Flexible periphery sealing structure 20 can be by (example
As) silicones, elastomeric material or any other suitable shape adaptive material be made, such as it would be recognized by those skilled in the art that
's.The different zones around the circumference of mask body 12 of flexible periphery sealing structure 20 can have different sections to configure.Respectively
Planting the configuration of other flexible periphery sealing structures 20 will become will be apparent to those skilled in the art.In one embodiment,
Compared with flexible periphery sealing structure 20, the rigid element 21 of mask body 12 is made up of relatively more rigid material.For example, face
Cover main body 12 can be made up of makrolon or other suitable materials.
Mask body 12 can be formed by two-step insert molding process.For example rigid element 21 can be by mould first
System, and be then inserted into the second mould for flexible periphery sealing structure 20, the flexible periphery sealing structure quilt
Injection moulding and form around rigid element 21 and/or formed therein.
In the exemplary embodiment, face shield assembly 10 is included, and there are piece volumes to be 17.02cm3Mask body 12 and tool
It is 34.11cm to have piece volumes3Sealing structure 20.
In one embodiment, taken for mask body 12 to be installed to the helmet component 11 on the head of pediatric patients 27
Bonnet form with band.It is also possible, however, to use mask body 12 to be fixed to the arbitrary structures on pediatric patients head.One
In individual embodiment, helmet component 11 is arranged to three kinds of different colours, and pink tone is used for girl, and blue color is used for boy,
And sex neutral color (for example, yellow).In diagram embodiment as shown in Figure 1A and 1B, two (figures of helmet band 46
One is only shown in 1B) in the end sections of each (unnumbered) spiral by the helmet keep tab 24 elongated open
50, and end sections (unnumbered) spiral of bottom helmet band 40 passes through the elongated open 130 that the helmet is attached intermediate plate 14.One
In individual embodiment, the end sections include hook material, and back bend to the adjoining formed by loop material taken with bar
Surface is engaged so that formation shackle (or VELCROTM) type connection.It should be appreciated, however, that exist many other modes be used for will
The end sections of helmet band are fixed to its own, or are fixed to helmet attachment intermediate plate 14 and/or helmet attachment tabs 24, make
For non-limiting examples, for example snap connection, hasp or locking fixture.The helmet 11 is adjustable, because band 44,46 can be with
Further pulled on and keep the opening 50 or the helmet of tab 24 to be attached the elongated open of intermediate plate 14 by the helmet, it is smaller to adapt to
The head sizes of diameter.
In addition, in another embodiment, the end sections and helmet band that can provide helmet band 44,46 keep tab
24 or the helmet be attached intermediate plate 14 more longlasting attachment.For example, once being incited somebody to action by the way that band 44,46 is adjusted into desired length
Helmet component 11 is coupled to pediatric patients 27, then the free end of band 44,46 permanently can back be coupled to band 44,46
On, for example by by the overlapping band it is glued, suture or rivet together.The band 44,46 of helmet component 11 can be
It is elastic or stiff, and can extend behind the head of pediatric patients 27, mask body 12 is fixed on into paediatrics suffers from
On person 27, wherein flexible periphery sealing structure 20 is engaged with pediatric patients face seal.
In detail in the claims, any element symbol being placed in bracket should not be construed as limiting claim.
Word " comprising " or "comprising" are not precluded from being listed in depositing for other element or steps outside the element or step in claim
.In the device claim for listing several parts, in these parts it is several with a kind of hardware or identical hardware come
Implement.Appear in the word " one " before element and " one " is not precluded from the presence of these multiple elements.Listing several portions
In any device claim of part, several in these parts can be implemented with a kind of hardware or identical hardware.Mutual
Some elements are not intended that these elements can not be used in combination with described in different dependent claims.
Although for purposes of illustration it is now recognized that to present invention progress on the basis of most practical and most preferred embodiment
It is described in detail, it is to be understood that these details are used for the purpose of the purpose, and the present invention is not limited to these disclosed realities
Example is applied, but on the contrary, it is contemplated that covers the change in appended spirit and scope by the claims and equivalent arrangements.Example
Such as, it will be understood that the present invention is expected within the bounds of possibility, one or more features of any embodiment can with it is any other
One or more features of embodiment are combined.
Claims (15)
1. a kind of be used in the face shield assembly (10) being transported to stream of therapeutic gas in the system of pediatric patients air flue, the set of mask
Part includes:
Mask body (12) with opening (13), the opening is suitable to receive treatment gas supply;With
Flexible periphery sealing structure (20) with the first side (504) and opposite the second side (508), first side is connected to
The mask body, second side includes opening (510), the opening be suitable to at least with the noses of the pediatric patients and
Mouth shape is in surrounding relationship to receive the pediatric patients face so that engage to second side seal pediatric patients face
Circumference, the opening by height (H) and width (W) limit, and the height and the width of the opening ratio between about 0.83
To in the range of about 0.87.
2. paediatrics face shield assembly according to claim 1, it is characterised in that the ratio of the height and the width of the opening
Rate is about 0.83.
3. paediatrics face shield assembly according to claim 1, it is characterised in that the opening have about 60.5mm height and
About 73.0mm width.
4. paediatrics face shield assembly according to claim 1, it is characterised in that the paediatrics face shield assembly also includes selectivity
Ground is connected to the helmet component (11) of the mask body.
5. paediatrics face shield assembly according to claim 4, it is characterised in that the helmet component includes the head of bonnet pattern
Helmet component.
6. paediatrics face shield assembly according to claim 5, it is characterised in that the helmet component is intended to use including instruction
The color of the sex of the pediatric patients of the helmet component.
7. paediatrics face shield assembly according to claim 6, it is characterised in that the helmet component is one of the following:
Blueness to indicate male's pediatric patients, or to indicate the pink of female patient.
8. a kind of be used to that the system that gas is transported to pediatric patients air flue will to be treated, the system includes:
Pressure/air-flow generation system (42);
Tubing element (40), the tubing element has the first end that is connected to the pressure/air-flow generation system and opposite
Second end;
Face shield assembly (10), the face shield assembly includes:
Mask body (12) with opening (13), described be open is connected to second end of the tubing element and suitable for warp
The treatment gas supply from the pressure/air-flow generation system is received by the tubing element;With
Flexible periphery sealing structure (20), the flexible periphery sealing structure has the first side (504) and the second opposite side
(508), first side is connected to the mask body, and second side includes opening (510), the opening be suitable to so that
Few face with noses and mouth shape of the pediatric patients the receiving pediatric patients in surrounding relationship so that second side
Sealingly engage the circumference of the pediatric patients face;And
It is selectively coupled to the helmet component (11) of the mask body, second side of the flexible periphery sealing structure
In the opening by height (HI) and width (WI) limit, and the height and the width of the opening ratio between about 0.83 to
In the range of about 0.87.
9. system according to claim 8, it is characterised in that second side of the flexible periphery sealing structure is opened
Mouth has about 60.5mm height and about 73mm width.
10. system according to claim 8, it is characterised in that the helmet component includes the helmet component of bonnet pattern.
11. system according to claim 10, it is characterised in that the helmet component is intended to use the head including instruction
The color of the sex of the pediatric patients of helmet component.
12. system according to claim 11, it is characterised in that the helmet component is one of the following:To refer to
Show the blueness of male's pediatric patients, or to indicate the pink of female patient.
13. a kind of external member, including:
Used in the face shield assembly (10) being transported to stream of therapeutic gas in the system of pediatric patients air flue, the face shield assembly bag
Include:
Mask body (12) with opening (13), the opening is suitable to receive treatment gas supply;And
Flexible periphery sealing structure (20) with the first side (504) and opposite the second side (508), first side is connected to
The mask body, and second side includes opening (510), the opening is suitable to the nose at least with the pediatric patients
With the mouth shape receiving in surrounding relationship pediatric patients face so that engage the pediatric patients face to second side seal
The circumference in portion, the opening is by height (HI) and width (WI) limit, and the height and the width of the opening ratio between about
In the range of 0.83 to about 0.87;And
Multiple helmet components, each helmet component can be connected to the face shield assembly so that mode may be selected, at least one
Helmet component includes being suitable to indicate that the color of male patient, and at least another helmet component includes being suitable to indicate that female patient
Color.
14. external member according to claim 13, it is characterised in that each helmet component includes the helmet of bonnet pattern
Component.
15. external member according to claim 14, it is characterised in that being suitable to indicate that the color of male patient includes blueness
Tone, and it is suitable to indicate that the color of female patient includes pink tone.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201261656737P | 2012-06-07 | 2012-06-07 | |
US61/656,737 | 2012-06-07 | ||
PCT/IB2013/054390 WO2013182952A1 (en) | 2012-06-07 | 2013-05-28 | Pediatric total facemask cross-reference to related applications; |
Publications (2)
Publication Number | Publication Date |
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CN104470572A CN104470572A (en) | 2015-03-25 |
CN104470572B true CN104470572B (en) | 2017-09-22 |
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ID=48803582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201380036685.9A Active CN104470572B (en) | 2012-06-07 | 2013-05-28 | Paediatrics full facepiece mask |
Country Status (7)
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US (1) | US20150297854A1 (en) |
EP (1) | EP2858703B1 (en) |
JP (1) | JP6195914B2 (en) |
CN (1) | CN104470572B (en) |
BR (1) | BR112014030323A2 (en) |
RU (1) | RU2635467C2 (en) |
WO (1) | WO2013182952A1 (en) |
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CN108553726B (en) | 2013-04-11 | 2021-07-06 | 费雪派克医疗保健有限公司 | Flexible mask coupling |
US10159813B2 (en) | 2014-05-21 | 2018-12-25 | Atom Medical Corporation | Gas supply mask apparatus |
US10232137B2 (en) * | 2014-05-22 | 2019-03-19 | Resmed Limited | Patient interface |
DE102014013796A1 (en) * | 2014-09-23 | 2016-03-24 | Weinmann Geräte für Medizin GmbH + Co. KG | Mask pillow for a full face mask |
JP6739429B2 (en) | 2014-10-30 | 2020-08-12 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | Interconnect assembly and support assembly including same |
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US11339770B2 (en) | 2016-12-13 | 2022-05-24 | Koninklijke Philips N.V. | Mask with primary and secondary air delivery |
FR3091654B1 (en) * | 2019-01-14 | 2023-05-12 | Stiplastics | INHALATION CHAMBER |
CA3119117C (en) * | 2020-06-05 | 2023-05-09 | Edward Bernard | Manufacturing method for a hood type ventilation device |
WO2023247520A1 (en) * | 2022-06-20 | 2023-12-28 | Tiki Safety Ab | Method of manufacturing a full-face mask for an air purifying respirator and such a mask |
CN118121804A (en) * | 2024-04-16 | 2024-06-04 | 常州市儿童医院(常州市第六人民医院) | Atomizing helmet for children respiratory tract treatment |
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Also Published As
Publication number | Publication date |
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WO2013182952A1 (en) | 2013-12-12 |
JP2015518768A (en) | 2015-07-06 |
JP6195914B2 (en) | 2017-09-13 |
BR112014030323A2 (en) | 2017-06-27 |
US20150297854A1 (en) | 2015-10-22 |
RU2635467C2 (en) | 2017-11-13 |
EP2858703B1 (en) | 2016-11-23 |
EP2858703A1 (en) | 2015-04-15 |
RU2014153530A (en) | 2016-07-27 |
CN104470572A (en) | 2015-03-25 |
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