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CN104352881A - Traditional Chinese medicinal composition for treating damp-heat type chronic cervicitis - Google Patents

Traditional Chinese medicinal composition for treating damp-heat type chronic cervicitis Download PDF

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Publication number
CN104352881A
CN104352881A CN201410488351.1A CN201410488351A CN104352881A CN 104352881 A CN104352881 A CN 104352881A CN 201410488351 A CN201410488351 A CN 201410488351A CN 104352881 A CN104352881 A CN 104352881A
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parts
radix
rhizoma
heat type
chronic cervicitis
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杨建平
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

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Abstract

A traditional Chinese medicinal composition for treating damp-heat type chronic cervicitis is prepared from the following medicines: rhizoma atractylodis, golden cypress, semen coicis, gentian, cape jasmine, Scutellaria baicalensis, Plantain seed, akebia stem, rhizoma alismatis, Smilax glabra, raw yam, madder, cuttlefish bone, raw keel, raw oyster shell, radix sophorae flavescentis, Paeonia lactiflora Pall. and velamen or branches of Ailanthus altissima(Mill.) Swingle. The above medicines can be made into any common oral preparation (a decoction, pills and capsules) according to a conventional Chinese herbal preparation method.

Description

A kind of Chinese medicine composition being used for the treatment of damp-heat type chronic cervicitis
Technical field:
The invention belongs to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition being used for the treatment of damp-heat type chronic cervicitis.
Background technology:
Chronic cervicitis is more than after childbirth, miscarriage or surgical injury cervix uteri, and pathogen invades and causes infection.Many performances without acute process clinically, pathogen mainly invades the part that endocervix and columnar epithelium cover, and endocervix pleat is many, and pathogen hides herein, infects not easy-clear, often forms chronic cervicitis.Sickness rate accounts for the more than half of married woman, and inflammatory loci is around the external os of vervix and cervical canal.Primary disease belongs to the traditional Chinese medical science " leukorrheal diseases " category.Damp-heat type chronic cervicitis cardinal symptom is profuse leukorrhea, and yellow skin or HUANGBAI(sic) are held concurrently mutually, and matter is thick; Susceptible to lose temper due to restlessness, distending pain in the chest and hypochondrium, bitter taste greasy taste in the mouth, xerostomia is not for drink.
Clinical treatment damp-heat type chronic cervicitis is comparatively thorny, and the oral leukorrhagia stopping disease of general treatment or anti-inflammatory drugs, cure the symptoms, not the disease, do not reach the object for the treatment of.
Summary of the invention:
Technical scheme of the present invention there is provided a kind of Chinese medicine composition of damp-heat type chronic cervicitis, is be that raw material is prepared from by the Chinese medicine of following weight proportion:
Rhizoma Atractylodis 9-15 part, Cortex Phellodendri 9-15 part, business rice 9-15 part, Radix Gentianae 6-12 part, Fructus Gardeniae 6-12 part, Radix Scutellariae 6-12 part, Semen Plantaginis 9-15 part, Caulis Akebiae 3-9 part, Rhizoma Alismatis 6-12 part, Rhizoma Smilacis Glabrae 9-15 part, Rhizoma Dioscoreae 12-18 part, Radix Rubiae 6-12 part, Os Sepiae 9-15 part, Os Draconis 12-18 part, Concha Ostreae 12-18 part, Radix Sophorae Flavescentis 6-12 part, Radix Paeoniae Alba 6-12 part, Cortex Ailanthi 6-12 part, every part be 1 gram.
The optimum weight proportioning of technical solution of the present invention is:
Rhizoma Atractylodis 12 parts, Cortex Phellodendri 12 parts, 12 parts, business rice, Radix Gentianae 9 parts, Fructus Gardeniae 9 parts, Radix Scutellariae 9 parts, Semen Plantaginis 12 parts, Caulis Akebiae 6 parts, Rhizoma Alismatis 9 parts, Rhizoma Smilacis Glabrae 12 parts, Rhizoma Dioscoreae 15 parts, 9 parts, Radix Rubiae, Os Sepiae 12 parts, Os Draconis 15 parts, Concha Ostreae 30 parts, Radix Sophorae Flavescentis 9 parts, Radix Paeoniae Alba 9 parts, Cortex Ailanthi 9 parts, every part are 1 gram.
The present invention is a kind of instant effect, good effect, Chinese drugs agentia without any side effects.
The traditional Chinese medical science is thought: treatment damp-heat type chronic cervicitis should with Shugan Qingre, dampness removing leukorrhagia stopping for Therapeutic Principle.Radix Gentianae, Fructus Gardeniae, Radix Scutellariae, Caulis Akebiae, Rhizoma Atractylodis, Cortex Phellodendri, business rice, Rhizoma Smilacis Glabrae Shugan Qingre in side; Rhizoma Dioscoreae, Radix Rubiae, Os Sepiae, Os Draconis, Concha Ostreae, Radix Sophorae Flavescentis, Radix Paeoniae Alba, Cortex Ailanthi, Semen Plantaginis, Rhizoma Alismatis dampness removing leukorrhagia stopping; Said medicine compatibility uses, synergism, thus the object reaching treatment.
Detailed description of the invention:
After medicine of the present invention configures according to component, can conventionally be fried into decoction and take, also can manufacture Chinese medicine pill by conventional method and take, capsule can also be become to take according to the daily dosimetric system of Chinese herbal medicine.
For proving clinical efficacy and the safety of medicine of the present invention further.69 routine patients are selected to carry out clinical observation to medicine of the present invention.
In 69 routine patients, January is a course for the treatment of, effective 45 examples; Effective 22 examples; Invalid 2 examples; Total effective rate 97.1%.Whole use the present invention treats, and therapeutic outcome is in table 1.
Rear curative effect statistical result treated by table 1
Patient Number of cases Effective (%) Effectively (%) Invalid (%) Total effective rate (%)
Take one the course for the treatment of person 20 18(90) 2(10) 0(0) 20(100)
Take two the course for the treatment of person 21 15(71.4) 6(29.6) 0(0) 21(100)
Take two the course for the treatment of above person 28 12(42.3) 14(50) 2(7.7) 26(92.3)
Amount to 69 45(65.2) 22(31.9) 2(2.9) 67(97.1)
Criterion of therapeutical effect: effective: profuse leukorrhea, yellow skin or HUANGBAI(sic) are held concurrently mutually, and matter is thick, susceptible to lose temper due to restlessness, distending pain in the chest and hypochondrium transference cure; Effective: profuse leukorrhea, yellow skin or HUANGBAI(sic) are held concurrently mutually, and matter is thick, susceptible to lose temper due to restlessness, and distending pain in the chest and hypochondrium symptom is extenuated or disappeared; Invalid: without significant change before and after treatment.
Therapeutic Method:
Usage and consumption: adopt the medicament prepared by the embodiment of the present invention, its usage and consumption as follows: (1) decoction: first dose adds water 700 milliliters and decoct to 200 milliliters, second dose adds water 500 milliliters and decocts to 200 milliliters, every day twice, sooner or later empty clothes; (2) capsule: every content of dispersion 0.4 gram; Every day 3 times, each 2, warm water takes; (3) pill: every 9 grams, ball.Every day 3 times, each 1 ball, warm water takes.
Embodiment (1):
Treat a Chinese medicine composition for damp-heat type chronic cervicitis, be made up of the raw material of following weight proportion:
Rhizoma Atractylodis 12 parts, Cortex Phellodendri 12 parts, 12 parts, business rice, Radix Gentianae 9 parts, Fructus Gardeniae 9 parts, Radix Scutellariae 9 parts, Semen Plantaginis 12 parts, Caulis Akebiae 6 parts, Rhizoma Alismatis 9 parts, Rhizoma Smilacis Glabrae 12 parts, Rhizoma Dioscoreae 15 parts, 9 parts, Radix Rubiae, Os Sepiae 12 parts, Os Draconis 15 parts, Concha Ostreae 30 parts, Radix Sophorae Flavescentis 9 parts, Radix Paeoniae Alba 9 parts, Cortex Ailanthi 9 parts, every part are 1 gram.
Decoct into decoction after said medicine being mixed, first dose adds water 700 milliliters and decocts to 200 milliliters, and second dose adds water 500 milliliters and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
Embodiment (2):
Treat a Chinese medicine composition for damp-heat type chronic cervicitis, be made up of the raw material of following weight proportion:
Rhizoma Atractylodis 9 parts, Cortex Phellodendri 9 parts, 9 parts, business rice, Radix Gentianae 6 parts, Fructus Gardeniae 6 parts, Radix Scutellariae 6 parts, Semen Plantaginis 9 parts, Caulis Akebiae 3 parts, Rhizoma Alismatis 6 parts, Rhizoma Smilacis Glabrae 9 parts, Rhizoma Dioscoreae 12 parts, 6 parts, Radix Rubiae, Os Sepiae 9 parts, Os Draconis 12 parts, Concha Ostreae 12 parts, Radix Sophorae Flavescentis 6 parts, Radix Paeoniae Alba 6 parts, Cortex Ailanthi 6 parts, every part are 1 gram.
Both No. 0 capsule has been loaded after fine powder crosses 1500 mesh sieves, every content of dispersion 0.4 gram by being ground into after the mixing of each component of above-mentioned weight.Every day 3 times, each 2, warm water takes.
Embodiment (3):
Treat a Chinese medicine composition for damp-heat type chronic cervicitis, be made up of the raw material of following weight proportion:
Rhizoma Atractylodis 15 parts, Cortex Phellodendri 15 parts, 15 parts, business rice, Radix Gentianae 12 parts, Fructus Gardeniae 12 parts, Radix Scutellariae 12 parts, Semen Plantaginis 15 parts, Caulis Akebiae 9 parts, Rhizoma Alismatis 12 parts, Rhizoma Smilacis Glabrae 15 parts, Rhizoma Dioscoreae 18 parts, 12 parts, Radix Rubiae, Os Sepiae 15 parts, Os Draconis 18 parts, Concha Ostreae 18 parts, Radix Sophorae Flavescentis 12 parts, Radix Paeoniae Alba 12 parts, Cortex Ailanthi 12 parts, every part are 1 gram.
Pill is made, 9 grams, every ball by being ground into after fine powder crosses 1500 mesh sieves after each component mixing of above-mentioned weight.Every day 3 times, each 1 ball, warm water takes.

Claims (4)

1. being used for the treatment of a Chinese medicine composition for damp-heat type chronic cervicitis, it is characterized in that, is be made up of the medicine of following weight:
Rhizoma Atractylodis 9-15 Fen, Yellow cypress 9-15 part, business rice 9-15 part, Radix Gentianae 6-12 part, Fructus Gardeniae 6-12 part, Radix Scutellariae 6-12 part, Semen Plantaginis 9-15 part, Caulis Akebiae 3-9 part, Rhizoma Alismatis 6-12 part, Rhizoma Smilacis Glabrae 9-15 part, Rhizoma Dioscoreae 12-18 part, Radix Rubiae 6-12 part, Os Sepiae 9-15 part, Os Draconis 12-18 part, Concha Ostreae 12-18 part, Radix Sophorae Flavescentis 6-12 part, Radix Paeoniae Alba 6-12 part, Cortex Ailanthi 6-12 part, every part be 1 gram.
2. the Chinese medicine composition of damp-heat type chronic cervicitis according to claim 1, it is characterized in that, be made up of the medicine of following weight:
Rhizoma Atractylodis 12 Fen, Yellow cypress 12 parts, 12 parts, business rice, Radix Gentianae 9 parts, Fructus Gardeniae 9 parts, Radix Scutellariae 9 parts, Semen Plantaginis 12 parts, Caulis Akebiae 6 parts, Rhizoma Alismatis 9 parts, Rhizoma Smilacis Glabrae 12 parts, Rhizoma Dioscoreae 15 parts, 9 parts, Radix Rubiae, Os Sepiae 12 parts, Os Draconis 15 parts, Concha Ostreae 30 parts, Radix Sophorae Flavescentis 9 parts, Radix Paeoniae Alba 9 parts, Cortex Ailanthi 9 parts, every part are 1 gram.
3. a kind of Chinese medicine composition for the treatment of damp-heat type chronic cervicitis according to claim 1,2, is characterized in that, method of Chinese medicinal routinely can be prepared into the conventional oral formulations of any one.
4. a kind of Chinese medicine composition for the treatment of damp-heat type chronic cervicitis according to claim 3, it is characterized in that, described oral formulations is decoction, pill, capsule.
CN201410488351.1A 2014-09-14 2014-09-14 Traditional Chinese medicinal composition for treating damp-heat type chronic cervicitis Pending CN104352881A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784590A (en) * 2015-04-23 2015-07-22 龚灿锋 Traditional Chinese medicine for treating chronic cervicitis
CN104800496A (en) * 2015-05-13 2015-07-29 青岛辰达生物科技有限公司 Traditional Chinese medicine preparation for treating recurrent chronic cervicitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317326A (en) * 2000-04-10 2001-10-17 陈江辉 Detoxicating compound oral liquid and its preparing process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317326A (en) * 2000-04-10 2001-10-17 陈江辉 Detoxicating compound oral liquid and its preparing process

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
尤昭玲,等: "《妇产科疾病药疗食疗全书》", 30 September 2009, 湖南科学技术出版社 *
李元文,等: "《中医性学》", 31 January 2013, 北京科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784590A (en) * 2015-04-23 2015-07-22 龚灿锋 Traditional Chinese medicine for treating chronic cervicitis
CN104800496A (en) * 2015-05-13 2015-07-29 青岛辰达生物科技有限公司 Traditional Chinese medicine preparation for treating recurrent chronic cervicitis

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Application publication date: 20150218