CN104288606A - Chinese medicinal tablets for treating acute glomerulonephritis - Google Patents

Abstract

The invention discloses Chinese medicinal tablets for treating acute glomerulonephritis, belonging to the technical field of Chinese medicaments. The Chinese medicinal tablets are prepared from the following raw medicaments in parts by weight: 25-30 parts of fresh rehmannia, 15-20 parts of figwort, 25-30 parts of poria cocos, 25-30 parts of rhizoma alismatis, 13-18 parts of polyporus umbellatus, 12-16 parts of mole cricket, 15-20 parts of plantain seeds, 20-25 parts of lalang grass rhizome, 12-18 parts of coix seeds, 15-20 parts of moutan bark, 15-20 parts of rhubarb, 20-30 parts of centella, 15-20 parts of field thistle, 15-20 parts of motherwort, 15-22 parts of hedyotis diffusa, 15-22 parts of nightshade, 18-24 parts of Chinese siphonostegia herb, 15-22 parts of forsythia, 20-25 parts of yam, 15-20 parts of astragalus root, 12-18 parts of red bean and 16-22 parts of fructus aurantii. The Chinese medicinal tablets can be used for strengthening the body resistance to eliminate pathogenic factors and consolidating the curative effect, are convenient to administrate, have a significant treatment effect on the acute glomerulonephritis and play an important role in later modulation.

Description

A kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis

Technical field

The present invention relates to a kind of medicine for the treatment of acute glomerulonephritis, belong to technical field of Chinese medicines, specifically a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis.

Background technology

Acute glomerulonephritis is one of urinary system commonly encountered diseases, frequently-occurring disease.Think that its pathogeny is that metainfective immunoreation causer occupies the majority at present, clinically divide again streptococcal infection to cause and non-streptococcal infection causes two kinds.Described herein two examples all belong to the former, clinical manifestation mainly contains: often have upper respiratory tract infection premorbid 1-3 week as streptococcal infection histories such as pharyngolaryngitis, tonsillitis and skin infections, then unexpected onset, be common with edema, hematuria, can occur together heat, headache, feel sick, tachypnea, soreness of waist lumbago, anorexia, tired and hypertension, edema in various degree time hypourocrinia, hematuria, albuminuria etc., renal function can be undermined.Western medical treatment is mainly had a rest, give low albumen, low salt diet, limiting moisture, and enter infection control, symptomatic treatment etc., as proper in time in treated, major part can be recovered, and the some patients initial stage is easily confused treatment flu or upper respiratory disease, and to being in a bad way, under microscopy, hematuria and albuminuria continue the long period, can continue development further and cause renal insufficiency.The traditional Chinese medical science uses determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, Chinese medicine, and treatment acute glomerulonephritis, can treating both the principal and secondary aspects of a disease.The traditional Chinese medical science thinks that acute glomerulonephritis take edema as primary symptom, belongs to traditional Chinese medical science edema scope, is called " water ", and is divided into edema due to wind pathogen, stony edema etc. according to different symptoms in Huangdi's Internal Classics." Ling Shu Miraculous Pivot or Divine Axis watery distension " section is described in detail its symptom, as " water has begun also, slightly swelling of the eyelids, and as the shape newly crouched, its notable and rashing pulsation of common carotid artery, time is coughed, cold over the region between the genitalia and thigh, puffiness of the legs, and abdomen is large, and its water becomes.With hands by its abdomen, rise, ascites as if water being contained within the abdomen conveniently, this its time also." primary disease is divided into the large class of YIN edema, YANG edema two by " danxi's experiential therapy edema ", adopt so far.The etiology and pathogenesis of primary disease can be summarized as wind, wet (wet, the noxious dampness of water, damp and hot), diet, impairment caused by overstrain.Wind impairing the lung; The wet impairment of the spleen, diet is the impairment of the spleen also; Impairment caused by overstrain kidney, causes lung to lose logical tune.Spleen loses and transfers, and kidney loses folding, and have no right to functioning of bladder eventually, three burnt water channel mistake departments, water liquid stops gathering, and spreads unchecked skin, forms edema.Allly experience ailment said due to cold or exposure, aqueous vapor, noxious dampness, damp and hot all heresies, see exterior heat, excess syndrome person, the present invention controls by YANG edema opinion; All improper diet and overtiredness, excess of sexual intercourse, damage healthy energy, be shown in interior deficiency, cold syndrome person, how to control from YIN edema opinion.The present invention controls according to YANG edema opinion, provides a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis, and the Chinese herbal medicine using Chinese tradition is raw material, meets the theory of Chinese medicine, has good therapeutic effect.

Summary of the invention

The invention provides a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis, the Chinese herbal medicine using Chinese tradition is raw material, meets the theory of Chinese medicine, has good therapeutic effect.

The property of medicine of Chinese herbal medicine selected by the present invention and function cure mainly and are respectively:

Radix Rehmanniae [nature and flavor] sweetness and bitterness, cold.[return through] enters the heart, liver, kidney channel.[function cures mainly] heat clearing away, removing heat from blood, promotes the production of body fluid.Control epidemic febrile disease impairment of YIN, large hot excessive thirst, crimson tongue, coma, macule, spit blood, epistaxis, asthenia hectic fever due to YIN-deficiency, hemoptysis, quenches one's thirst, constipation, metrorrhagia.1. " not Lu ": " housewife people's metrorrhagia blood is more than, and the thin heart on puerperal blood, absolutely vexed, be harmful to the health, vaginal bleeding due to excessive movement of fetus, tire do not fall, falling down wrist is rolled over, blood stasis stagnant blood, and epistaxis is spitted blood, and all smashes drink." 2. " property of medicine opinion ": " Xie Zhure, removing blood stasis, the tonneau moon water blockage exhausted, also dredging water passages, smashes thin trusted subordinate, can repercussive blood.Empty and the frequent fever of patient, adds and uses it." 3. " Treatise on Dietetic Therapy ": " main toothache, spits blood, injured." 4. " four tones of standard Chinese pronunciation book on Chinese herbal medicine ": " black beard and hair." 5. " medicine origin ": " removing heat from blood, (profit) skin is dry, goes all wet.Steeping in wine is up." 6. " medicine class on the analogy of natural things ": " removing heat from blood, enriches blood, the kidney invigorating water kidney-YIN being deficient." 7. " Bencao Congxin ": " disappear small intestine fire, clearing away dryness gold, and flat all blood is inverse, and repercussive stimulates the menstrual flow.Control and tell nosebleed metrorrhagia, pyretic toxicity dysentery, the intestines and stomach is as burnt, and typhoid fever pestilence pox is demonstrate,proved, Zhu great Re, drinking a large amount of water due to extreme thirst, and folding falls exhausted muscle, sharp defecation."

Radix Scrophulariae [nature and flavor] is sweet, bitter, salty, is slightly cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.

Poria [nature and flavor] is sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

Rhizoma Alismatis [nature and flavor] is sweet, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.

Polyporus [nature and flavor] is sweet, light, flat.[return through] returns kidney, urinary bladder channel.[function cures mainly] promoting diuresis to eliminate damp pathogen.For dysuria, edema, has loose bowels, stranguria with turbid discharge, leukorrhagia.

Gryllotalpa [nature and flavor]: salty-cold, nontoxic.Gui Jing: stomach, bladder.Effect: diuretic relieving constipation, blood circulation promoting and blood stasis dispelling, diuretic, relieving constipation, removing toxic substances., scrofula, carbuncle malignant boil unfavorable for edema, defecation.

Semen Plantaginis [nature and flavor] is sweet, is slightly cold.[return through] returns liver, kidney, lung, small intestine meridian.[function cures mainly] clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.

Rhizoma Imperatae [nature and flavor] is sweet, cold.[return through] returns lung, stomach, urinary bladder channel.[function cures mainly] cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.

Semen Coicis [nature and flavor] is sweet, light, cool.[return through] returns spleen, stomach, lung meridian.[function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.

Cortex Moutan [nature and flavor] is bitter, pungent, is slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.

Herba Centellae [nature and flavor] bitter, acrid, cold.Return liver,spleen,kidney warp.[function cures mainly] clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For jaundice due to damp-heat, heatstroke is suffered from diarrhoea, sand Stranguria stranguria with blood, carbuncle sore tumefacting virus, injury from falling down.

Herba Cirsii [nature and flavor] sweet, bitter, cold.[return through] GUIXIN, Liver Channel.[function cures mainly] herb: cooling blood for hemostasis, removing blood stasis to reduce swelling.For epistaxis, spit blood, hematuria, has blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus.Root stock: hepatitis.

Herba Leonuri [nature and flavor] is bitter, pungent, is slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.

Fructus Forsythiae [nature,taste and action]: Chinese medicine bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Mongolian medicine bitter in the mouth, cool in nature.Clearly " association's day ", antidiarrheal.[curing mainly]: Chinese medicine controls calentura from the beginning of, anemopyretic cold, heating is vexed, laryngopharynx swelling and pain, macule, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, pyretic stranguria.Mongolian medicine is harnessed the Yellow River subcutaneous ulcer, intestinal twinge, and " association's day " is sick, intestinal heat.

Rhizomadioscoreae [nature and flavor] is flat, sweet, nontoxic.[return through] enters lung, spleen, kidney, stomach.[function cures mainly] spleen invigorating, thick the intestines and stomach, tonifying the lung, kidney tonifying.Diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, seminal emission leukorrhagia, frequent micturition, quenches one's thirst, uterine prolapse.

The Radix Astragali [nature and flavor] is sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.

Semen Phaseoli [nature and flavor] is sweet, sour, flat.[return through] GUIXIN, small intestine meridian.[function cures mainly] inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi limb swells, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.

Fructus Aurantii [nature and flavor] is bitter, pungent, sour, temperature.[return through] returns spleen, stomach warp.[function cures mainly] regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.

Radix Et Rhizoma Rhei [nature and flavor] is bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.

Herba Solani Nigri [nature and flavor] is bitter, cold.Slightly poisonous.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema.For cat fever, toothache, chronic bronchitis, dysentery, urinary system infection, mastitis, leucorrhea, cancer; Carbuncle furuncle furuncle is controlled in external, pemphigus, venom.

Herba Hedyotidis Diffusae [nature and flavor] is sweet, light, cool.[return through] enters stomach, large intestine, small intestine meridian.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria; Furuncle carbuncle is controlled in external, venom.

Herba Siphonostegiae [nature and flavor] is bitter, cool.[function cures mainly] clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling.Harness the Yellow River subcutaneous ulcer, dysuria, edema abdominal distention, falls and damages stasis of blood pain, dysentery, stranguria with blood, leukorrhagia, menoxenia, lump in the abdomen, stops the stasis of blood stomachache puerperal.1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " diuresis, treats in stomach damp and hot, or the jaundice of eye core, or whole body general edema with yellowish skin.2. " Zhiwu Mingshi Tukao ": " control glutted, pleasantly to reduce phlegm, send out poison all.Swollen under " 3. " will planted by northeast medicine ": " removing blood stasis, lower blood and relieving pain, disease more than puerperal, only incised wound blood, the cardiac and abdominal pain therapeutic method to keep the adverse QI flowing downwards, watery distension vim and vigour, logical married woman's passages through which vital energy circulates, crux, only cholera is dropped, children's's hematuria." 4. " Chinese herbal medicine is commonly used in Shanghai ": " clearing away heat and promoting diuresis.Control oliguria with reddish urine, jaundice, hepatitis." 5. " Guizhou medical herbs ": " induces sweat, and cold expelling heat, dampness removing dispels the wind." 6. Jinhua " conventional Chinese herbal folk proved recipe a collection of selected materials ": " controls cholecystitis, acute nephritis, leukorrhagia."

The invention provides a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 25-30 part, Radix Scrophulariae 15-20 part, Poria 25-30 part, Rhizoma Alismatis 25-30 part, Polyporus 13-18 part, Gryllotalpa 12-16 part, Semen Plantaginis 15-20 part, Rhizoma Imperatae 20-25 part, Semen Coicis 12-18 part, Cortex Moutan 15-20 part, Radix Et Rhizoma Rhei 15-20 part, Herba Centellae 20-30 part, Herba Cirsii 15-20 part, Herba Leonuri 15-20 part, Herba Hedyotidis Diffusae 15-22 part, Herba Solani Nigri 15-22 part, Herba Siphonostegiae 18-24 part, Fructus Forsythiae 15-22 part, Rhizomadioscoreae 20-25 part, Radix Astragali 15-20 part, Semen Phaseoli 12-18 part, Fructus Aurantii 16-22 part;

Described a kind of Chinese medicinal tablet preparation method for the treatment of acute glomerulonephritis, concrete steps are:

1. prepare before decocting, choose marmite and drinking water, take medical material in proportion, draft class medical material soaks 2 hours, and fruit tubers medical material soaks 3 hours;

2. decoct, add water to medical material surface and do not have forefinger two joint, first intense fire boils, then slow fire keeps micro-boiling, and add Radix Et Rhizoma Rhei after decocting 20 points and continue decoction 10 minutes, when again decocting, moisturizing exceedes medicinal residues 2 centimetres, decocts 20 minutes; Decoct three times, merge the medicinal liquid after decocting, concentrate and make extractum, be spray dried to fine powder, cross No. 7 medicines sieves, add auxiliary agent, repeatedly mix, put into rotary tablet press;

3. check, packaging.

Described a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 26-29 part, Radix Scrophulariae 16-19 part, Poria 26-29 part, Rhizoma Alismatis 26-29 part, Polyporus 14-17 part, Gryllotalpa 13-15 part, Semen Plantaginis 16-19 part, Rhizoma Imperatae 21-24 part, Semen Coicis 12-18 part, Cortex Moutan 16-19 part, Radix Et Rhizoma Rhei 16-19 part, Herba Centellae 21-29 part, Herba Cirsii 16-19 part, Herba Leonuri 16-19 part, Herba Hedyotidis Diffusae 16-21 part, Herba Solani Nigri 16-21 part, Herba Siphonostegiae 19-23 part, Fructus Forsythiae 16-21 part, Rhizomadioscoreae 21-24 part, Radix Astragali 16-19 part, Semen Phaseoli 13-17 part, Fructus Aurantii 17-21 part.

Described a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 27 parts, Radix Scrophulariae 17 parts, 28 parts, Poria, Rhizoma Alismatis 28 parts, Polyporus 15 parts, Gryllotalpa 14 parts, Semen Plantaginis 17 parts, Rhizoma Imperatae 23 parts, Semen Coicis 16 parts, Cortex Moutan 18 parts, Radix Et Rhizoma Rhei 17 parts, Herba Centellae 26 parts, Herba Cirsii 17 parts, Herba Leonuri 18 parts, Herba Hedyotidis Diffusae 19 parts, Herba Solani Nigri 19 parts, Herba Siphonostegiae 20 parts, Fructus Forsythiae 18 parts, Rhizomadioscoreae 22 parts, the Radix Astragali 17 parts, Semen Phaseoli 15 parts, Fructus Aurantii 19 parts.

Usefulness of the present invention: with Radix Rehmanniae, Radix Scrophulariae, Rhizoma Imperatae YIN nourishing and the production of body fluid promoting, in case diuretic more impairment of YIN, plays the merit of nourishing YIN and clearing away heat diuretic altogether; With Cortex Moutan, Herba Cirsii, from Rhizoma Imperatae cooling blood for hemostasis; The heat-clearing and toxic substances removing such as Herba Hedyotidis Diffusae, Herba Centellae, Fructus Forsythiae; Gryllotalpa, Semen Plantaginis, Rhizoma Alismatis clearing away heat and promoting diuresis, Gryllotalpa still has very strong activating blood and promoting diuresis effect, with Herba Leonuri phase 5, anti-hemostasis can stay the stasis of blood, strengthen diuretic effect again; Radix Et Rhizoma Rhei, Herba Solani Nigri, Herba Siphonostegiae have the merit of heat clearing away, removing toxic substances, diuretic concurrently; By the merit of Poria, Rhizomadioscoreae, the Radix Astragali, Fructus Aurantii reinforcement righting, based on the object reaching spleen invigorating, the kidney invigorating effected a permanent cure for the later stage; The Radix Astragali in side be all medicines of QI invigorating, " book on Chinese herbal medicine is looked for the truth " meaning Radix Astragali again can the kidney invigorating, and Semen Coicis eliminating dampness by diuresis is subsided a swelling, Poria spleen invigorating QI invigorating, and Fructus Aurantii promoting the circulation of QI to induce diuresis, prevents the Radix Astragali QI invigorating from causing obstruction of QI, and Semen Phaseoli diuretic dehumidifies.Entirely can strengthening body resistance and dispelling evil, consolidate curative effect, and taking convenience, play an important role to the medical treatment of primary disease later stage.

Detailed description of the invention

Embodiment 1

Treat a Chinese medicinal tablet for acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 25 parts, Radix Scrophulariae 15 parts, 25 parts, Poria, Rhizoma Alismatis 25 parts, Polyporus 13 parts, Gryllotalpa 12 parts, Semen Plantaginis 15 parts, Rhizoma Imperatae 20 parts, Semen Coicis 12 parts, Cortex Moutan 15 parts, Radix Et Rhizoma Rhei 15 parts, Herba Centellae 20 parts, Herba Cirsii 15 parts, Herba Leonuri 15 parts, Herba Hedyotidis Diffusae 15 parts, Herba Solani Nigri 15 parts, Herba Siphonostegiae 18 parts, Fructus Forsythiae 15 parts, Rhizomadioscoreae 20 parts, the Radix Astragali 15 parts, Semen Phaseoli 12 parts, Fructus Aurantii 16 parts;

Described a kind of Chinese medicinal tablet preparation method for the treatment of acute glomerulonephritis, concrete steps are:

1. prepare before decocting, choose marmite and drinking water, take medical material in proportion, draft class medical material soaks 2 hours, and fruit tubers medical material soaks 3 hours;

2. decoct, add water to medical material surface and do not have forefinger two joint, first intense fire boils, then slow fire keeps micro-boiling, and add Radix Et Rhizoma Rhei after decocting 20 points and continue decoction 10 minutes, when again decocting, moisturizing exceedes medicinal residues 2 centimetres, decocts 20 minutes; Decoct three times, merge the medicinal liquid after decocting, concentrate and make extractum, be spray dried to fine powder, cross No. 7 medicines sieves, add auxiliary agent, repeatedly mix, put into rotary tablet press;

3. check, packaging.

Embodiment 2

Treat a Chinese medicinal tablet for acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 26 parts, Radix Scrophulariae 16 parts, 26 parts, Poria, Rhizoma Alismatis 26 parts, Polyporus 14 parts, Gryllotalpa 13 parts, Semen Plantaginis 16 parts, Rhizoma Imperatae 21 parts, Semen Coicis 12 parts, Cortex Moutan 16 parts, Radix Et Rhizoma Rhei 16 parts, Herba Centellae 21 parts, Herba Cirsii 16 parts, Herba Leonuri 16 parts, Herba Hedyotidis Diffusae 16 parts, Herba Solani Nigri 16 parts, Herba Siphonostegiae 19 parts, Fructus Forsythiae 16 parts, Rhizomadioscoreae 21 parts, the Radix Astragali 16 parts, Semen Phaseoli 13 parts, Fructus Aurantii 17 parts.

Preparation method is with embodiment 1

Embodiment 3

Treat a Chinese medicinal tablet for acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 27 parts, Radix Scrophulariae 17 parts, 28 parts, Poria, Rhizoma Alismatis 28 parts, Polyporus 15 parts, Gryllotalpa 14 parts, Semen Plantaginis 17 parts, Rhizoma Imperatae 23 parts, Semen Coicis 16 parts, Cortex Moutan 18 parts, Radix Et Rhizoma Rhei 17 parts, Herba Centellae 26 parts, Herba Cirsii 17 parts, Herba Leonuri 18 parts, Herba Hedyotidis Diffusae 19 parts, Herba Solani Nigri 19 parts, Herba Siphonostegiae 20 parts, Fructus Forsythiae 18 parts, Rhizomadioscoreae 22 parts, the Radix Astragali 17 parts, Semen Phaseoli 15 parts, Fructus Aurantii 19 parts.

Preparation method is with embodiment 1

Embodiment 4

Treat a Chinese medicinal tablet for acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 29 parts, Radix Scrophulariae 19 parts, 29 parts, Poria, Rhizoma Alismatis 29 parts, Polyporus 17 parts, Gryllotalpa 15 parts, Semen Plantaginis 19 parts, Rhizoma Imperatae 24 parts, Semen Coicis 18 parts, Cortex Moutan 19 parts, Radix Et Rhizoma Rhei 19 parts, Herba Centellae 29 parts, Herba Cirsii 19 parts, Herba Leonuri 19 parts, Herba Hedyotidis Diffusae 21 parts, Herba Solani Nigri 21 parts, Herba Siphonostegiae 23 parts, Fructus Forsythiae 21 parts, Rhizomadioscoreae 24 parts, the Radix Astragali 19 parts, Semen Phaseoli 17 parts, Fructus Aurantii 21 parts.

Preparation method is with embodiment 1

Embodiment 5

Treat a Chinese medicinal tablet for acute glomerulonephritis, be made up of the crude drug of following weight proportion:

Radix Rehmanniae 30 parts, Radix Scrophulariae 20 parts, 30 parts, Poria, Rhizoma Alismatis 30 parts, Polyporus 18 parts, Gryllotalpa 16 parts, Semen Plantaginis 20 parts, Rhizoma Imperatae 25 parts, Semen Coicis 18 parts, Cortex Moutan 20 parts, Radix Et Rhizoma Rhei 20 parts, Herba Centellae 30 parts, Herba Cirsii 20 parts, Herba Leonuri 20 parts, Herba Hedyotidis Diffusae 22 parts, Herba Solani Nigri 22 parts, Herba Siphonostegiae 24 parts, Fructus Forsythiae 22 parts, Rhizomadioscoreae 25 parts, the Radix Astragali 20 parts, Semen Phaseoli 18 parts, Fructus Aurantii 22 parts.

Preparation method is with embodiment 1

Using method of the present invention: each 5-8 sheet, every day 3-5 time, or follow the doctor's advice.

Curative effect:

MethodsThe cases enrolled: patient 560 example choosing acute glomerulonephritis through outpatient service, 560 routine patients select for random-blind and are divided into two groups.The oral hydrochlorothiazide of western medical treatment and guarantor's potassium class diuretic, treatment by Chinese herbs uses formula tablet of the present invention.

Efficacy determination: adopt 4 grade standards

Recovery from illness clinical improvements rate >=95%;

Effective clinical improvements rate < 95%, >=60%;

Effective clinical improvement rate < 60%, >=20%;

Invalid clinical improvements rate < 20%;

Therapeutic outcome is in table 1

?	Recovery from illness (routine %)	Effective (routine %)	Effectively (routine %)	Invalid (routine %)	Total effective rate (%)
						Western medicine effect	47（16.7)	59(21.1)	93(33.3)	81(28.9)	71.1
Treatment by Chinese herbs effect of the present invention	241(86.1)	22(7.8)	12（4.4）	1(0.4)	98.6

Interpretation of result: random-blind choosing grouping, two group memberships do not exist biased and significant difference.

The comparison of cure rate:

Western medicine group cure rate is 16.7%, and treatment by Chinese herbs group cure rate of the present invention is 86.1%, through X ²inspection, (p<0.01), illustrates that treatment by Chinese herbs group cure rate of the present invention is significantly higher than western medicine group cure rate.

Total effective rate compares: total effective rate is the case that removing is invalid, remaining percentage.

Western medicine group is 71.1%, and treatment by Chinese herbs group of the present invention is 98.6%, through X ²inspection, (p<0.01), illustrates that treatment by Chinese herbs group total effective rate of the present invention is significantly higher than western medicine group total effective rate.

To sum up, by the analysis to two groups, can reach a conclusion, the Be very effective of Chinese medicinal tablet treatment acute glomerulonephritis of the present invention is higher than Western medicine hydrochlorothiazide and protect potassium class diuretic, has significant therapeutic effect.

Model case:

Case 1 king so-and-so, sex: man, the age: 30 years old.Cardinal symptom: hematuria, edema, hypertension, weak, xerostomia, poor appetite, anasarca, dizziness, oliguria, lumbago, through routine urinalysis and blood routine examination, examine after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 1 formula Chinese medicinal tablet, each 6, every day 3 times, within 1 month, effectively cure, follow up a case by regular visits to and do not recur.

Case 2 Zhao, sex: female, 50 years old age.Cardinal symptom: hematuria, edema, hypertension, edema, weak, dizzy, oliguria, lumbago, through routine urinalysis and blood routine examination, examine after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 2 formula Chinese medicinal tablet, each 6, every day 3 times, within 1 month, effectively cure, follow up a case by regular visits to and do not recur.

Case 3 king so-and-so, sex: female.Age: 35 years old.Cardinal symptom: hematuria, edema, hypertension, puffiness of face, gradually to abdominal distention, edema of pair of lower extremities, dark coloured urine, oliguria, weak, ridicule pain, headache, xerostomia, poor appetite, through routine urinalysis and blood routine examination, examines after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 3 formula Chinese medicinal tablet, each 5, every day 3 times, within 25 days, effectively cure, follow up a case by regular visits to and do not recur.

Case 4 Liu, sex: man, age: 25 years old.Cardinal symptom: hematuria, edema, hypertension, puffiness of face, gradually to abdominal distention, edema of pair of lower extremities, dark coloured urine, oliguria, weak, ridicule pain, headache, xerostomia, poor appetite, through routine urinalysis and blood routine examination, examines after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 4 formula Chinese medicinal tablet, each 7, every day 3 times, within 1 month, effectively cure, follow up a case by regular visits to and do not recur.

Case 5 Liu so-and-so, sex: female, age: 65 years old.Cardinal symptom: hematuria, edema, hypertension, puffiness of face, gradually to abdominal distention, edema of pair of lower extremities, dark coloured urine, oliguria, weak, ridicule pain, headache, xerostomia, poor appetite, through routine urinalysis and blood routine examination, examines after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 5 formula Chinese medicinal tablet, each 6, every day three times, within 1.5 months, effectively cure, follow up a case by regular visits to and do not recur.

Case 6 beam, sex: man, age: 45 years old.Cardinal symptom: hematuria, edema, hypertension, puffiness of face, gradually to abdominal distention, edema of pair of lower extremities, dark coloured urine, oliguria, weak, ridicule pain, headache, xerostomia, poor appetite, through routine urinalysis and blood routine examination, examines after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 3 formula Chinese medicinal tablet, each 6, every day 4 times, within 1 month, effectively cure, follow up a case by regular visits to and do not recur.

Case 7 Guo so-and-so, sex: man, the age: 33 years old.Cardinal symptom: hematuria, edema, hypertension, puffiness of face, gradually to abdominal distention, edema of pair of lower extremities, dark coloured urine, oliguria, weak, ridicule pain, headache, xerostomia, poor appetite, through routine urinalysis and blood routine examination, examines after examination in hospital as " acute glomerulonephritis ".Use the agent of embodiment 1 formula Chinese medicinal tablet, each 8, every day 5 times, within 1 month, effectively cure, follow up a case by regular visits to and do not recur.

Claims (3)

1. treat a Chinese medicinal tablet for acute glomerulonephritis, it is characterized in that being made up of the crude drug of following weight proportion:

Radix Rehmanniae 25-30 part, Radix Scrophulariae 15-20 part, Poria 25-30 part, Rhizoma Alismatis 25-30 part, Polyporus 13-18 part, Gryllotalpa 12-16 part, Semen Plantaginis 15-20 part, Rhizoma Imperatae 20-25 part, Semen Coicis 12-18 part, Cortex Moutan 15-20 part, Radix Et Rhizoma Rhei 15-20 part, Herba Centellae 20-30 part, Herba Cirsii 15-20 part, Herba Leonuri 15-20 part, Herba Hedyotidis Diffusae 15-22 part, Herba Solani Nigri 15-22 part, Herba Siphonostegiae 18-24 part, Fructus Forsythiae 15-22 part, Rhizomadioscoreae 20-25 part, Radix Astragali 15-20 part, Semen Phaseoli 12-18 part, Fructus Aurantii 16-22 part;

Described a kind of Chinese medicinal tablet preparation method for the treatment of acute glomerulonephritis, concrete steps are:

1. prepare before decocting, choose marmite and drinking water, take medical material in proportion, draft class medical material soaks 2 hours, and fruit tubers medical material soaks 3 hours;

2. decoct, add water to medical material surface and do not have forefinger two joint, first intense fire boils, then slow fire keeps micro-boiling, and add Radix Et Rhizoma Rhei after decocting 20 points and continue decoction 10 minutes, when again decocting, moisturizing exceedes medicinal residues 2 centimetres, decocts 20 minutes; Decoct three times, merge the medicinal liquid after decocting, concentrate and make extractum, be spray dried to fine powder, cross No. 7 medicines sieves, add auxiliary agent, repeatedly mix, put into rotary tablet press;

3. check, packaging.

2. a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis according to claim 1, is characterized in that being made up of the crude drug of following weight proportion:

Radix Rehmanniae 26-29 part, Radix Scrophulariae 16-19 part, Poria 26-29 part, Rhizoma Alismatis 26-29 part, Polyporus 14-17 part, Gryllotalpa 13-15 part, Semen Plantaginis 16-19 part, Rhizoma Imperatae 21-24 part, Semen Coicis 12-18 part, Cortex Moutan 16-19 part, Radix Et Rhizoma Rhei 16-19 part, Herba Centellae 21-29 part, Herba Cirsii 16-19 part, Herba Leonuri 16-19 part, Herba Hedyotidis Diffusae 16-21 part, Herba Solani Nigri 16-21 part, Herba Siphonostegiae 19-23 part, Fructus Forsythiae 16-21 part, Rhizomadioscoreae 21-24 part, Radix Astragali 16-19 part, Semen Phaseoli 13-17 part, Fructus Aurantii 17-21 part.

3. a kind of Chinese medicinal tablet for the treatment of acute glomerulonephritis according to claim 1, is characterized in that being made up of the crude drug of following weight proportion:

Radix Rehmanniae 27 parts, Radix Scrophulariae 17 parts, 28 parts, Poria, Rhizoma Alismatis 28 parts, Polyporus 15 parts, Gryllotalpa 14 parts, Semen Plantaginis 17 parts, Rhizoma Imperatae 23 parts, Semen Coicis 16 parts, Cortex Moutan 18 parts, Radix Et Rhizoma Rhei 17 parts, Herba Centellae 26 parts, Herba Cirsii 17 parts, Herba Leonuri 18 parts, Herba Hedyotidis Diffusae 19 parts, Herba Solani Nigri 19 parts, Herba Siphonostegiae 20 parts, Fructus Forsythiae 18 parts, Rhizomadioscoreae 22 parts, the Radix Astragali 17 parts, Semen Phaseoli 15 parts, Fructus Aurantii 19 parts.