CN1042064A - Diagnosis instrument for ventricle blood vessel of human body - Google Patents
Diagnosis instrument for ventricle blood vessel of human body Download PDFInfo
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- CN1042064A CN1042064A CN 88107390 CN88107390A CN1042064A CN 1042064 A CN1042064 A CN 1042064A CN 88107390 CN88107390 CN 88107390 CN 88107390 A CN88107390 A CN 88107390A CN 1042064 A CN1042064 A CN 1042064A
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Abstract
A kind of human body cardiovascular disease automatic diagnostic instrument, the various electrophysiology informations of human body that various pick offs are imported into carry out one respectively to several times waveform processing, the various signals in the same time are synchronously taken out in the CPU control of computer, send into successively simultaneously and adopt guarantor's circuit, multiway analog switch, modulus and digital to analog converter, parallel input, output interface, hand over computer that synchronous various signals are carried out various conversion, the integrated treatment of superposition, it reflects it is not conspicuous on the electrophysiological spike shape, the characteristic point that prior art can't be differentiated, make the diagnosis of cardiovascular disease more accurate, also can be in conjunction with clinical verification and existing diagnostic method of development and mathematical model.
Description
The present invention relates to a kind of diagnosis instrument for ventricle blood vessel of human body, particularly a kind of automatic medical instrument that comprises microcomputer.
The armarium of relevant cardiovascular disease of the prior art, none is not only the single or primary electrophysiology information of human body to be handled, to help the doctor that patient disease is diagnosed and to treat.By chart of these instrument gained or the like, only to doctor's the reference role of making a definite diagnosis very big limitation, this quasi-instrument that is reflected in highlightedly among US-460899 and CN86206895 and the CN86104809A reflects just that basically the human body electrophysiology information is the less characteristic point of number, characteristic point to the level and smooth part enrichment of various electrophysiology information waveforms then can't reflect, the analysis-by-synthesis of characteristic point separately to several electrophysiology informations, accurately make its position, can't accomplish, this just makes medical mathematics model comparatively coarse, inaccuracy, often vary with each individual, so the diagnosis to disease is inaccurate, even cause mistaken diagnosis maybe can't diagnose to the disease that has.
Purpose of the present invention just provides and a kind ofly not only shows on the human body electrophysiology information waveform characteristic point more intuitively, and reflects on these waveforms it is not apparent, the characteristic point that prior art can't be offered an explanation.Above-mentioned characteristic point is need carry out calculus to original waveform according to cardiovascular disease diagnosis, processing such as superposition and obtaining, with the disease of distinguishing and the diagnosis prior art can't be distinguished and diagnose out, making the diagnosis of disease more become accurate ， And can be in conjunction with the technical scheme of the mathematical model of clinical experience checking and the existing cardiovascular disease diagnosis of development.
The formation of the present invention that realizes above-mentioned purpose comprises, computer, parallel input and output interfaces (PIO), modulus and digital to analog converter, multiway analog switch, control circuit, pick off, clock, the parameter input equipment, adopt guarantor's circuit, printer display and drawing apparatus, the outstanding difference of itself and prior art is: the human body electrophysiology information (neuroelectricity that pick off is imported into, electrocardio, hear sounds, myoelectricity, blood pressure, impedance, admittance, brain, machcardiogram) calculus that carries out one to n time is respectively handled, various signals are synchronously taken out in the CPU control of computer, the waveshape signal that phase place in the same time is leading is implemented delay process, with the various signals in the same time, send into successively and adopt guarantor's circuit, the multi-channel analog circuit, analog-digital converter, parallel input, output interface, hand over computer synchronous various signals to be carried out various conversion, the integrated treatment of superposition.
Fig. 1 human body cardiovascular disease automatic diagnostic instrument theory diagram
Fig. 2 human body cardiovascular disease automatic diagnostic instrument software flow pattern
Fig. 3 control circuit schematic diagram
Fig. 4 clocking scheme
The wiring diagram of delay line in Fig. 5 delay circuit
Fig. 6 electrocardio ripple, hear sounds involve machcardiogram superposition principle sketch map
Fig. 7 working mode selection schematic diagram of device.
Obtain neuroelectricity, electrocardio, hear sounds, myoelectricity, blood pressure, impedance, admittance, brain electricity and machcardiogram signal with various corresponding electrophysiology information pick offs in an embodiment of the present invention, these original waveform can not reflect the characteristic point of smooth on the waveform, be every rising or downward trend, maximum or minima or the like.As shown in Figure 1, the present invention in the waveform processing partial design calculus circuit and delay circuit, the calculus that above-mentioned waveform is carried out one to n time is as required handled, obtain the characteristic point of smooth enrichment on the waveform that prior art can't determine respectively, owing to handle through calculus, can produce the deviation on the phase place between each waveform, this deviation will influence the present invention carries out analysis-by-synthesis to various waveforms in the same time period purpose, the employing of delay circuit is exactly getting in the time period in the various waveforms, the leading waveform of phase place is implemented delay process, to guarantee the synchronous of various waveforms.Delay circuit of the present invention can adopt many types.What use among this embodiment is the delay line and the active four-pole network delay circuit of passive four terminal network, the wiring diagram of delay line as shown in Figure 5, practice according to the clinical diagnosis of human body cardiovascular disease, in the present invention, various signals keep the synchronous of strictness, and the time that computer-controlled synchronizing signal is sent, it is in full accord that the time parameter point when setting up with mathematical model keeps, in this embodiment, with second heart sound signal S
2As the starting point of choosing various sync waveforms, the software in (also available other signal, for example Electrocardiographic R ripple etc. only need that the software program of computer is done corresponding change and get final product as the starting point of sync waveform), the computer is at first judged second heart sound signal S
2, and select second heart sound signal S
2As synchronizing signal, when second heart sound finished, the CPU of computer sent control command simultaneously, makes clock, sampling hold circuit, and multiway analog switch, modulus and digital to analog converter are worked simultaneously, and the corresponding program that brings into operation.Selecting the second heart sound signal is to finish because of T ripple in second heart sound and the electrocardiogram to take place simultaneously as synchronizing signal, according to the physiology as can be known, the T ripple finishes, mean finishing of an activity cycle of heart, so, finish with the T ripple and to send lock-out pulse to make equipment carry out work be rational, other similar waveforms also can be used as synchronizing signal, respectively through sampling hold circuit, multiway analog switch, parallel input, output interface, enter computer carries out various conversion, superposition to synchronous various signals integrated treatment through the various signals of above-mentioned waveform processing.One of example of this superposition combination is in the clinical practice of cardiovascular disease diagnosis, cardiac function normally whether, most important, and heart spray the PEP value in early stage directly show cardiac function normally whether, the PEP value is little, shows that cardiac function is good, and the PEP value is big, show that then cardiac function is bad, and the value of PEP is:
PEP＝QS
2-ET
QS wherein
2Be Q point time distance between the second heart sound master composition to phonocardiogram on the electrocardiogram, so, QS be obtained
2Parameter just must be with electrocardiogram and phonocardiogram superposition.And then with carotid artery impulse wave superposition, can obtain the PEP value as shown in Figure 6, in addition, computer also can be to some other important clinical Diagnostic parameters, obtain by the superposition combination, as:
During the Qb=time distance that electrocardiogram Q point is ordered to admittance second differential b;
During the XO=second heart sound main constituent distance during first peak dot behind admittance one subdifferential ripple;
QS
1During this time=the time distance of electrocardiogram Q point between the first heart sound main constituent;
After by computer various electrophysiology information signals in the same time period being carried out superposition combination, the important parameter of the various clinical diagnosises of obtaining will improve widely to the direct accurate rate of diagnosis of human body cardiovascular disease.And realize purpose of the present invention.
In the present invention, the external equipment of computer also includes printer display and drawing apparatus, at any time show diagnostic result or each characteristic point parameter, printer also can be printed diagnostic result or each characteristic point parameter at any time, because the various characteristic points of being analyzed are the bidimensional parameters by amplitude and time decision, time value (can be used soft clock by clock, also available hardware clock) record is determined, the accuracy of each characteristic point parameter of gathering in order to guarantee, the time-delay of signal and collection and clock are strict synchronous, the zero-time of each signals collecting strictly satisfies the requirement of mathematical model.Mathematical model is solidificated among the EPROM with program, this device start can be moved automatically, and make it have the manual intervention function.The man-machine conversation mode is adopted in the parameter input.
The present invention is also having a working mode selection device as shown in Figure 7 between line output, input interface (PIO) and the computer, and it is the end by software inquiry switch, connects A mouth or the B mouth of PIO, and the other end ground connection of switch is formed.Working method can select continuous and interrupted mode, continuously-running duty especially important effect to be played in critical patient's monitoring.The clock circuit schematic diagram as shown in Figure 4, it is made up of computer CPU and CTC and address decoder.Control circuit is by the control line of key switch K through buffer 74LS244 access computer CPU, address wire A
1, A
2, A
3Meeting analog multichannel switch AD7501 with control line EN forms, export drawing apparatus to, see Fig. 3, every corresponding waveform of key switch, CPU regularly inquires about on off state, if when certain road waveform need be drawn, CPU then sent control command and address code to analog multichannel switch, the signal of then required drawing is promptly delivered to drawing apparatus by analog multichannel switch and is drawn.
Diagnosis instrument for ventricle blood vessel of human body involved in the present invention, the various electrophysiology informations of human body are detected, carry out conversion superposition combination and Mathematical Modeling by computer and carry out analysis-by-synthesis and implement diagnosis to patient disease, it compared with prior art, its outstanding effect is:
1. quantitatively obtain the two-dimensional parameter of each physiologic information characteristic point, the various doctor's Mathematical Modelings of substitution, the diagnostic result that obtains angiocardiopathy exactly make the disease that originally can't diagnose and can't distinguish that the disease that comes is diagnosed and difference is come.
2. verify the Zheng Que Du And correct of existing mathematical model and perfect, make the diagnosis of disease more become accurate; Developing new mathematical model finds out the accurate diagnostic method of more cardiovascular disease next.Diagnostic result, the characteristic point parameter, various electrophysiology information ripples can deposit that computer is hard in, in the floppy disk, for scientific research is given information.
3. reliable, convenient, human computer conversation, manual intervention, working mode selection device, and Chinese and western language prints, and all from clinical practice, makes things convenient for the user.
4. only need to revise a little to model and program, just fast applicable to the different ethnic group diagnosis speed of different regions, be used for mass diagnosis and generaI investigation has better effect.
Claims (6)
1, a kind of human body cardiovascular disease automatic diagnostic instrument, comprise computer, parallel input and output interfaces (PIO), modulus and digital to analog converter, multiway analog switch, the control circuit pick off, clock, the parameter input equipment, adopt guarantor's circuit, printer, display and drawing apparatus, it is characterized in that: the human body electrophysiology information (neuroelectricity that pick off is imported into, electrocardio, hear sounds, myoelectricity, blood pressure, impedance, admittance, brain, the neck pulse wave) carrying out one respectively handles to several times calculus, various signals are synchronously taken out in the CPU control of computer, the waveform that phase place in the same time is leading is implemented delay process, with the various signals in the same time, send into successively simultaneously and adopt guarantor's circuit, multiway analog switch, analog-digital converter, parallel input, output interface, hand over computer synchronous various signals to be carried out various conversion, the integrated treatment of superposition.
2, human body cardiovascular disease automatic diagnostic instrument according to claim 1, it is characterized in that: various signals keep strictly synchronous, the time that computer-controlled synchronizing signal is sent, the time reference of setting up with mathematical model keeps in full accord, selects second heart sound S
2During as synchronizing signal, computer software is at first judged second heart sound S
2, at second heart sound S
2During end, computer CPU sends control command simultaneously, and clock sampling holding circuit, multiway analog switch, modulus and digital to analog converter are worked simultaneously, and the corresponding program that brings into operation.
3, according to claim 1 and 2 described human body cardiovascular disease automatic diagnostic instruments, it is characterized in that: mathematical model is solidificated among the EPROM with program, and the start back i.e. operation automatically, and the man-machine conversation mode is adopted in the parameter input.
4, according to claim 1 and 2 described human body cardiovascular disease automatic diagnostic instruments, it is characterized in that: between parallel input and output interfaces (PIO) and computer, one working mode selection device is arranged, it is that the other end ground connection of switch is formed by A mouth or the B mouth of a termination PIO of software inquiry switch.
5, according to claim 1 and 2 described human body cardiovascular disease automatic diagnostic instruments, it is characterized in that: control circuit is by the control line of key switch K through buffer 74LS244 access computer CPU, address wire A
1, A
2, A
3Meeting analog multichannel switch AD7501 with control line EN forms.
6, according to claim 1 and 2 described human body cardiovascular disease automatic diagnostic instruments, it is characterized in that: used delay circuit is the delay line and the active four-pole network delay circuit of passive four terminal network.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 88107390 CN1042064A (en) | 1988-10-22 | 1988-10-22 | Diagnosis instrument for ventricle blood vessel of human body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 88107390 CN1042064A (en) | 1988-10-22 | 1988-10-22 | Diagnosis instrument for ventricle blood vessel of human body |
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| Publication Number | Publication Date |
|---|---|
| CN1042064A true CN1042064A (en) | 1990-05-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 88107390 Pending CN1042064A (en) | 1988-10-22 | 1988-10-22 | Diagnosis instrument for ventricle blood vessel of human body |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100413464C (en) * | 2006-05-26 | 2008-08-27 | 中国人民解放军空军航空医学研究所 | Method and apparatus for continuously measuring blood pressure |
| CN107296602A (en) * | 2017-05-18 | 2017-10-27 | 天津市医疗器械研究所 | Electrocardioelectrode electrical property test instrument |
-
1988
- 1988-10-22 CN CN 88107390 patent/CN1042064A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100413464C (en) * | 2006-05-26 | 2008-08-27 | 中国人民解放军空军航空医学研究所 | Method and apparatus for continuously measuring blood pressure |
| CN107296602A (en) * | 2017-05-18 | 2017-10-27 | 天津市医疗器械研究所 | Electrocardioelectrode electrical property test instrument |
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