CN104189870A - Traditional Chinese medicine for treating allergic asthma - Google Patents
Traditional Chinese medicine for treating allergic asthma Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating allergic asthma, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 5-15 g of tendril-leaved fritillary bulb, 5-15 g of ephedra, 5-15 g of lumbricus, 5-15 g of platycodon root, 5-15 g of white mustard seed, 5-15 g of shizandra berry, 5-15 g of dried orange peel, 5-15 g of almond, 5-15 g of perillaseed, 5-15 g of cicada ecdysis, 10-20 g of atractylodes macrocephala, 10-20 g of membranous milkvetch root, 10-20 g of honeysuckle, 10-20 g of gypsum, 10-20 g of baical skullcap root, 10-20 g of prepared rhizome of rehmannia, 2-5 g of ginger, 2-5 g of jujube and 2-5 g of asarum. According to the traditional Chinese medicine provided by the invention, after the raw materials are combined, the drug effects have synergistic effect, so that the functions of diffusing the lung, eliminating phlegm, discharging pus, warming spleen and stomach for dispelling cold, strengthening the spleen and tonifying the kidney are achieved; moreover, the traditional Chinese medicine can be used for eliminating the clinical symptoms and changing the allergic condition for asthma patients, both symptoms and root causes of the disease are cured, and the remarkable toxic and side effects are avoided.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specially a kind of Chinese medicine for the treatment of allergic asthma.
Background technology
Allergic asthma is more than Juvenile onset, and patient often has the atopy body constitution to Cucumber allergy, can have obvious anaphylactogen contact history, or relevant with season.Primary disease premorbid has that nasopharynx is itched more, ophthalmic pruritus, sneeze, and the mucous membrane hypersusceptibility performances such as rhinorrhea and cough, can alleviate naturally or through treatment.How morbidity when rising in night or morning.Sickness rate 1%～11%, its sickness rate, mortality rate have the trend of increasing in recent years.
The treatment of allergic asthma be take doctor trained in Western medicine anti-inflammatory treatment at present as main, and this type of therapy is obtaining good curative effect aspect Control of asthma condition of illness, but the allergic constitution that can not correct asthma patient, therefore often recurrence very soon of asthma after drug withdrawal.So Western medicine can only take stopgap measures, can not effect a permanent cure.
Summary of the invention
The object of the invention is to overcome the deficiency of existing treatment, and a kind of Chinese medicine for the treatment of allergic asthma is provided, for asthma determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, have significant curative effect.
The technical scheme that technical solution problem of the present invention is taked is:
A Chinese medicine decoction for the treatment of allergic asthma, is characterized in that, by the raw material of following weight, is made: Bulbus Fritillariae Cirrhosae 5-15 gram, Herba Ephedrae 5-15 gram, Pheretima 5-15 gram, Radix Platycodonis 5-15 gram, Semen Sinapis Albae 5-15 gram, Fructus Schisandrae Chinensis 5-15 gram, Pericarpium Citri Reticulatae 5-15 gram, Semen Armeniacae Amarum 5-15 gram, Fructus Perillae 5-15 gram, Periostracum Cicadae 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Astragali 10-20 gram, Flos Lonicerae 10-20 gram, Gypsum Fibrosum 10-20 gram, Radix Scutellariae 10-20 gram, Radix Rehmanniae Preparata 10-20 gram, Rhizoma Zingiberis Recens 2-5 sheet, Fructus Jujubae 2-5, Herba Asari 2-5 gram.
The optimum weight proportioning of traditional Chinese medicinal composition raw materials of the present invention is: 10 grams of Bulbus Fritillariae Cirrhosae, 10 grams, Herba Ephedrae, 10 grams of Pheretimas, 10 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Semen Armeniacae Amarum, 10 grams of Fructus Perillaes, 10 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 15 grams of Gypsum Fibrosum, 15 grams of Radix Scutellariaes, 15 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
Preparation and instructions of taking:
First, by the Impurity removal of each crude drug, all medicines of receiving add 500 milliliters, water in marmite, decoct half an hour, and potion on the one, takes at twice, within 10 days, is a course for the treatment of.
Pharmacological action:
Bulbus Fritillariae Cirrhosae: lung moistening eliminating stagnation, antitussive reduces phlegm. control cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat.
Herba Ephedrae: diaphoresis, relieving asthma, diuretic.The cold table that cures the wound is real, and fever with chills is lossless, headache nasal obstruction, arthralgia, cough and asthma.
Pheretima: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.Control height fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula.
Radix Platycodonis: toil, flat.Enter lung, stomach warp.Open lung qi dispersing gas, the evacuation of pus of eliminating the phlegm.Control exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.
Semen Sinapis Albae: promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain. control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation vomiting, aphasia due to apoplexy, numb limbs and tense tendons.
Fructus Schisandrae Chinensis: astringe the lung, nourishing kidney, promotes the production of body fluid, receives antiperspirant, arresting seminal emission. and control the deficiency of the lung and breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain is won thin, chronic diarrhea chronic dysentery.
Pericarpium Citri Reticulatae: warm in nature, bitter in the mouth, pungent.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough ant phlegm.
Semen Armeniacae Amarum: expelling phlegm for arresting cough, relieving asthma, intestine moistening.Control exogenous cough, dyspnea with fullness of the chest, sore throat.Dryness of the intestine constipation.
Fructus Perillae: the therapeutic method to keep the adverse QI flowing downwards, expectorant, lung moistening, wide intestinal.Control cough with dyspnea, phlegm dyspnea, stagnation of QI constipation.
Periostracum Cicadae: loose wind heat, lung qi dispersing, determines convulsion.Control affection due to external wind and heat, cough hoarseness, measles is sent out not smooth thoroughly, rubella pruritus, pediatric epilepsy scared, conjunctival congestion, furuncle swelling toxin, tetanus.
The Rhizoma Atractylodis Macrocephalae: bitter sweet, temperature.Enter spleen, stomach warp.Spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive.Control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.
The Radix Astragali: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent. can cure mainly weakness of the spleen and stomach with it clinically, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
Flos Lonicerae: heat clearing away, removing toxic substances.Control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula.
Gypsum Fibrosum: Gypsum Fibrosum is cool in nature and can fall apart, expelling pathogenic factors from muscles for clearing heat, relieving restlessness is quenched the thirst, and has the saturating effect of a surname in clear, has the effect of antipyretic clearing stomach fire, is the panacea of bringing down a fever.Normal with
cortex Phellodendri,
indigo Naturalisdeng compatibility, outward in order to heat clearing away sore,
granulation promoting.Treatment
eczema, skin infection is not held back after bursting, burn due to hot liquid or fire etc.
Radix Scutellariae: hardship, cold.Enter the heart, lung, gallbladder, large intestine channel.Removing the relative excess fire, remuval of damp and hot, hemostasis, antiabortive.Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tells, is defeated in battle, collapses, leaks, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.
Radix Rehmanniae Preparata: both kind YIN nourishing of enriching blood, again can vital essence replenishing and marrow benifiting, cure mainly the cloudy disease of losing oligospermia of all blood deficiency.Major function nourishing the blood and yin, vital essence replenishing and marrow benifiting, for blood deficiency and yellow complexion, dizzy, cardiopalmus.
Rhizoma Zingiberis Recens, Fructus Jujubae: as guiding drug or adjuvant, Rhizoma Zingiberis Recens and Fructus Jujubae exist
prescriptionin there is cooperation
prescriptionin monarch, ministerial drug strengthen therapeutical effect, or directly treat minor symptom; In order to eliminate or to weaken the high strong property of the toxicity of monarch, ministerial drug or restriction monarch, ministerial drug; In seriously ill heresy very, in the time of may refusing to take medicine, can in prescription, work the effect of coordinating again; Can draw in prescription all medicines to sick institute; There is the effect of all medicines in mediation prescription.
Herba Asari: pungent, temperature.Enter lung, kidney channel.There is the effects such as expelling cold and relieving exterior syndrome, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, heat-clearing and toxic substances removing. control air-cooled headache, nasal sinusitis, laughs somebody to scorn, rheumatic arthralgia.
The traditional Chinese medical science thinks, it is " because of empty sensitization " that allergy is searched to the bottom, and the not empty irritated spontaneous recovery of lung spleen kidney, so treatment allergic asthma should be take lung benefiting strengthening spleen, tonifying kidney as main.The present invention is by after above drug regimen, and drug effect has synergism, plays out lung qi dispersing gas, the effect of the evacuation of pus of eliminating the phlegm, warming spleen and stomach for dispelling cold, strengthening spleen, tonifying kidney, when eliminating clinical symptoms, the allergic constitution of correcting asthma patient, reaches treating both the principal and secondary aspects of a disease, and without obvious toxic-side effects.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data: be selected from the outpatient service in year January in February, 2013 to 2014 and isolated from allergic asthmatic patients 127 examples of being in hospital, by the state of an illness, carry out stratified random, by study subject random assortment to treatment group (Chinese medicine) and matched group (Western medicine group).Treatment group 75 examples, 1～72 years old age, average 52.5 years old; Matched group 52 examples, 1～76 years old age, average 48 years old.Two groups of patient ages, the course of disease, state of an illness comparing difference not statistically significant (P>O.05), two groups have comparability.
2, diagnostic criteria:
(1) repeatedly outbreak pant, out of breath, uncomfortable in chest or cough, many with to contact allergen, cold air, physics, chemical irritation and viral upper respiratory tract infection, motion etc. relevant.
(2) expiratory phase of take is main wheezing sound at two lung audibles and be dispersed in or diffusivity when outbreak, and expiratory phase extends.
(3) above-mentioned symptom and sign can be alleviated or spontaneous remission through treatment.
(4) except other diseases causedly pant, out of breath, uncomfortable in chest and cough.
(5) its atypical clinical manifestations person's (as without obviously panting or sign), should at least possess following 1 pulmonary function test positive: 1. brinchial provocation test or motion activated test are positive; 2. the positive FEV1 of Bronchodilation Test increases >=12%, and FEV1 increases absolute value >=200ml; 3. (or 2 weeks) aberration rate >=20% in peak expiratory flow (PEF) day.
Meet 1～4 or 4,5 persons, can be diagnosed as asthma.
3, Therapeutic Method:
Treatment group: take medicine of the present invention, oral every day potion, every dose twice, serveing on 10 days is a course for the treatment of;
Matched group: Roxithromycin Tablets is oral, each 0.15g, every day 2 times, hismanal tablet is oral, and each 9mg, every day 1 time, 10 days is a course for the treatment of.
4, efficacy assessment standard:
Cure: the symptom of panting and pulmonary's wheezing sound disappear, and do not need any medicine, keep asymptomatic more than 1 year.
Effective: the symptom of panting and pulmonary's wheezing sound are clearly better.
Effective: the symptom of panting and pulmonary's wheezing sound take a favorable turn.
Invalid: the symptom of panting and pulmonary's wheezing sound are without taking a turn for the better or increasing the weight of.
5, therapeutic outcome
Two groups of therapeutic outcomes are as shown in table 1:
Table 1 liang group cure rate synopsis
| Group | Example time | Recovery from illness/example | Effective/example | Effectively/example | Invalid/example | Total effective rate (%) |
| Treatment group | 75 | 30 | 25 | 17 | 3 | 96.0 |
| Matched group | 52 | 7 | 12 | 16 | 17 | 67.3 |
Therapeutic outcome shows, treatment group respectively with the comparison of matched group total effective rate, difference has very significant (P < 0.001), and has no side effect through this medicine of clinical observation.
In sum, the present invention treats the Chinese medicine decoction of allergic asthma, through clinical trial, shows that it can effectively improve patient's symptom, sign, and without obvious toxic-side effects.
Two, model case
Case 1, Zou so-and-so, female, 45 years old.Patient's asthma 3 years, almost outbreak everyday of asthma recently, evening, cough increased the weight of, and especially after midnight, was all to spend at cough, asthma state, almost can not fall asleep.Removed hospital western medicines in treatment, produced effects bad.After take Drug therapy of the present invention, after the course for the treatment of, the state of an illness is just under control, cough alleviates, continual cure is after two courses for the treatment of, all transference cures, so far recurrence.
Case 2, Song, man, 59 years old.Suffer from allergic asthma 3 years, have cold wind to blow over or contact some penetrating odor after just feel suffocated, cough, asthma, seek medical advice in many ways, often suppress awake night from sleep, through multi-treatment poor effect.Through taking Drug therapy of the present invention after the course for the treatment of, asthma attack number of times reduces, and the symptom of coughing, feel suffocated obviously alleviates.Continue two courses for the treatment of of medication, above-mentioned symptom disappears, and complexion is better than in the past, and evening, sleep was normal, so far recurrence.
Case 3, king so-and-so, 1 years old 4 months, female.Infant suffers from allergic asthma, coughs up phlegm, feels suffocated, cough with asthma during morbidity, taken a lot of Western medicine, but the state of an illness again and again always, shows effect and suppresses especially the severity of breathing heavily when serious.Take a course for the treatment of of medicine of the present invention, symptoms of asthma is eased, dyspnea, the symptom such as uncomfortable in chest obviously alleviate, and the course for the treatment of of continuing to take medicine, asthma and cough frequency obviously reduces, breathe smooth and easy, after treatment after the course for the treatment of, various symptoms disappear substantially, feel very good, later stage check, then without rebound phenomenon.
The specific embodiment
Example 1: a kind of Chinese medicine for the treatment of allergic asthma, by the raw material of following weight, made: 10 grams of Bulbus Fritillariae Cirrhosae, 10 grams, Herba Ephedrae, 10 grams of Pheretimas, 10 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Semen Armeniacae Amarum, 10 grams of Fructus Perillaes, 10 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 15 grams of Gypsum Fibrosum, 15 grams of Radix Scutellariaes, 15 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
Preparation and instructions of taking: first by the Impurity removal of each crude drug, all medicines of receiving add 500 milliliters, water in marmite, decoct half an hour, and potion on the one, takes at twice, within 10 days, is a course for the treatment of.
Example 2: a kind of Chinese medicine decoction for the treatment of allergic asthma, by the raw material of following weight, made: 15 grams of Bulbus Fritillariae Cirrhosae, 15 grams, Herba Ephedrae, 10 grams of Pheretimas, 10 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Semen Armeniacae Amarum, 10 grams of Fructus Perillaes, 10 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 15 grams of Gypsum Fibrosum, 15 grams of Radix Scutellariaes, 15 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
Preparation and instructions of taking: with example 1.
Example 3: a kind of Chinese medicine decoction for the treatment of allergic asthma, by the raw material of following weight, made: 12 grams of Bulbus Fritillariae Cirrhosae, 12 grams, Herba Ephedrae, 12 grams of Pheretimas, 12 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Semen Armeniacae Amarum, 10 grams of Fructus Perillaes, 10 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 15 grams of Gypsum Fibrosum, 15 grams of Radix Scutellariaes, 15 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
Preparation and instructions of taking: with example 1.
Example 4: a kind of Chinese medicine decoction for the treatment of allergic asthma, by the raw material of following weight, made: 10 grams of Bulbus Fritillariae Cirrhosae, 10 grams, Herba Ephedrae, 10 grams of Pheretimas, 10 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Pericarpium Citri Reticulataes, 15 grams, Semen Armeniacae Amarum, 15 grams of Fructus Perillaes, 15 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 15 grams of Gypsum Fibrosum, 20 grams of Radix Scutellariaes, 20 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
Preparation and instructions of taking: with example 1.
Example 5: a kind of Chinese medicine decoction for the treatment of allergic asthma, by the raw material of following weight, made: 12 grams of Bulbus Fritillariae Cirrhosae, 12 grams, Herba Ephedrae, 12 grams of Pheretimas, 12 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Semen Armeniacae Amarum, 15 grams of Fructus Perillaes, 15 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 20 grams of Gypsum Fibrosum, 15 grams of Radix Scutellariaes, 15 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
Preparation and instructions of taking: with example 1.
Claims (2)
1. a Chinese medicine for the treatment of allergic asthma, is characterized in that, by the raw material of following weight, is made: Bulbus Fritillariae Cirrhosae 5-15 gram, Herba Ephedrae 5-15 gram, Pheretima 5-15 gram, Radix Platycodonis 5-15 gram, Semen Sinapis Albae 5-15 gram, Fructus Schisandrae Chinensis 5-15 gram, Pericarpium Citri Reticulatae 5-15 gram, Semen Armeniacae Amarum 5-15 gram, Fructus Perillae 5-15 gram, Periostracum Cicadae 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Astragali 10-20 gram, Flos Lonicerae 10-20 gram, Gypsum Fibrosum 10-20 gram, Radix Scutellariae 10-20 gram, Radix Rehmanniae Preparata 10-20 gram, Rhizoma Zingiberis Recens 2-5 sheet, Fructus Jujubae 2-5, Herba Asari 2-5 gram.
2. a kind of Chinese medicine for the treatment of allergic asthma according to claim 1, is characterized in that, by the raw material of following weight, is made: 10 grams of Bulbus Fritillariae Cirrhosae, 10 grams, Herba Ephedrae, 10 grams of Pheretimas, 10 grams of Radix Platycodoniss, 10 grams of Semen Sinapis Albaes, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Semen Armeniacae Amarum, 10 grams of Fructus Perillaes, 10 grams of Periostracum Cicadaes, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of the Radixs Astragali, 15 grams of Flos Loniceraes, 15 grams of Gypsum Fibrosum, 15 grams of Radix Scutellariaes, 15 grams, Radix Rehmanniae Preparata, 3, Rhizoma Zingiberis Recens, 3, Fructus Jujubae, 3 grams of Herba Asaris.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108201549A (en) * | 2018-03-13 | 2018-06-26 | 大连大学 | A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma and preparation method thereof |
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| CN101757516A (en) * | 2008-11-20 | 2010-06-30 | 赵欣 | Prescription of traditional Chinese medicine for treating infantile allergic asthma |
| CN103083539A (en) * | 2012-12-27 | 2013-05-08 | 王吉坤 | Chinese herbal compound for treating common respiratory system diseases |
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| CN108201549A (en) * | 2018-03-13 | 2018-06-26 | 大连大学 | A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma and preparation method thereof |
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