CN104188662A - Blood-sampling-free type blood sugar monitoring device and use method thereof - Google Patents
Blood-sampling-free type blood sugar monitoring device and use method thereof Download PDFInfo
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- CN104188662A CN104188662A CN201410418223.XA CN201410418223A CN104188662A CN 104188662 A CN104188662 A CN 104188662A CN 201410418223 A CN201410418223 A CN 201410418223A CN 104188662 A CN104188662 A CN 104188662A
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Abstract
The invention relates to the field of medical instruments, in particular to a blood-sampling-free type blood sugar monitoring device and a use method of the blood-sampling-free type blood sugar monitoring device. The blood-sampling-free type blood sugar monitoring device comprises a host and a PCB arranged in the host. The PCB is provided with an LCD display screen, a microprocessor, a blood sugar detection circuit, a storage module and a power module, wherein the blood sugar detection circuit, the storage module and the power module are electrically connected with the microprocessor. The blood sugar detection circuit comprises a blood sugar detection module. The PCB is further provided with a human body resistance collecting circuit electrically connected with the microprocessor. The human body resistance collecting circuit comprises a human body resistance collecting module used for detecting the value of resistance between two points of the human skin, and converting a detection result to a blood sugar value through the microprocessor to be displayed on the LCD display screen of the host. The human body blood sugar changes are reflected by testing skin resistance, a traditional mode that blood sampling is needed every time a blood sugar test is carried out is omitted, pains of patients are relieved, and the blood sugar changes can be conveniently mastered in time.
Description
Technical field
The present invention relates to medical instruments field, relate to specifically a kind of exempt to take a blood sample formula blood sugar monitoring equipment and using method thereof.
Technical background
Blood glucose value is for very important index of diabetes, so concerning a lot of diabetes patients, be just concerned about very much, during its tangible diagnosing diabetes, will judge from fasting blood sugar and latter two hours blood glucose value two aspects of meal.Euglycemia value on an empty stomach: fasting glucose normal range is 3.9-6.1mmol/L (70-110mg/dL), is diagnosed as diabetes higher than 7.0mmol/L (126mg/dL).The diagnostic criteria of diabetes is 7.0mmol or 126 milligrams of these standards so on an empty stomach, and you can find out that the empty stomach diagnosis of normal value and diabetes has gap.Somebody is neither normally, be also less than diabetes.We manage this symptom and are called fasting glucose and increase (impaired).Euglycemia value after meal: normally two hours blood glucose scopes are 3.9-7.8mmol/L (70-140mg/dL) after the meal.The diagnostic criteria of post-prandial glycemia is 11.1mmol or more than 200 milligrams.Between 140 and 200, also there is so a gap.If blood glucose is in this stage, we manage it and are called post-prandial glycemia and increase.This people, neither normal person neither diabetes patient.But to increase be danger close to this people's blood glucose, is easy to obtain diabetes.This people must be careful.Medicated cap is just suspended on his head.If pay no heed to, will soon put on the medicated cap of diabetes.Even the completely normal people of blood glucose, if possess some high risk factors, also must note prevent diabetes.Hyperglycemia is also conventionally the height in everybody said " three-hypers ".Therefore, particularly important to the monitoring of blood glucose value at any time.
Most blood glucose monitoring system is all to use blood sampling mode to test in the market, all needs blood glucose examination bar during blood sugar test, with various brands blood glucose meter be special-purpose assorted, can not be general between various brands.Blood glucose examination bar in the market has two kinds of blood sampling modes: the formula of bleeding and hydrocone type.The blood glucose examination bar of the formula of bleeding, needs blood sample many during test, blood sample need to be added drop-wise on examination bar, and drop of blood too much, very little or position is inaccurate all can affect test value.Although employing siphon is sucked blood automatically, the blood glucose examination bar of mode is tested accurately, somewhat expensive, and it is few to recycle number of times, and environmental impact factor is large etc.
In addition, also there is following shortcoming in most blood glucose meter:
1. accuracy is inadequate, and at present the international standard of blood glucose meter is while being greater than 4.2mmol/L, to be positive and negative 20%, that is to say in positive and negative 20% range of error it is all acceptable, and new international standard can be stipulated stricter restriction, and being greater than at 5.6 o'clock is positive and negative 15%.The result accuracy of hospital equipment can think 100%.
2. be subject to chaff interference impact.Be subject to the restriction of blood glucose meter reaction enzymes, instrument result can produce deviation because chaff interference exists, and such as oxygen, such as iodine tincture, hospital equipment is less influenced.
3. examined condition impact, temperature humidity height above sea level etc. all can affect blood glucose meter testing result.Hospital equipment has steady operation conditions, not affected by this.
4. be affected by human factors, whether blood collection procedure has pollutant, such as ethanol.Whether squeezing blood causes tissue fluid to sneak into sample.
Owing to relating to blood sampling, detect blood glucose value, except hospital is detected, the impact of the various factorss such as the how many environment of receiving of domestic detector, Professional knowledge, skilled operation degree, to monitoring result, all can produce very large error, therefore, need to develop a kind of without blood sampling, the blood glucose meter of amplitude of variation that just can Real-Time Monitoring self blood glucose, make patient can monitor more easily anywhere or anytime self change of blood sugar amplitude, to adjust in time living habit and diet collocation.
Summary of the invention
For the deficiency in above-mentioned technology, the invention provides a kind of exempt to take a blood sample formula blood sugar monitoring equipment and using method thereof, the method, by the resistance of test skin is reacted to the technology that blood sugar for human body changes, realizes change of blood sugar Real-Time Monitoring effect.
For solving the problems of the technologies described above, the present invention realizes by following scheme:
A kind of formula blood sugar monitoring equipment of exempting to take a blood sample, comprise main frame, be located at the pcb board in main frame, on described pcb board, be provided with LCD display, microprocessor, the blood sugar test circuit being electrically connected to microprocessor and the memory module being electrically connected to micro-processing, power module, described blood sugar test circuit comprises blood sugar test module, on pcb board, also be provided with the human body resistance Acquisition Circuit being electrically connected to microprocessor, this human body resistance Acquisition Circuit comprises human body resistance acquisition module, resistance value size between 2 of described human body resistance acquisition module human body skins, and the result detecting is converted to blood glucose value size by microprocessor be presented on the LCD display on main frame.
Further, be covered with some finger-type grooves under described host housing, and be provided with metal dots touched electrode at each finger-type groove front end, this metal dots touched electrode is connected with human body resistance Acquisition Circuit is anodal.
Further, in described host housing side, draw a wire, this wire is connected electrically in the negative pole of human body resistance Acquisition Circuit, and wire end connects grasping handle electrode, is provided with the metal electrode that a circle is connected with metal wire in wire on described grasping handle electrode.
Further, described finger-type groove is provided with three, respectively forefinger groove, middle finger groove, nameless groove, human body left index finger, middle finger, nameless Naked are pressed on finger-type groove, make metal in forefinger, middle finger, unknown and groove tap electrode contact, the naked grasping handle electrode of holding of right human hand, makes the right hand contact with metal electrode, forms resistance loop.
Further, in described human body resistance Acquisition Circuit, be connected with dual operational amplifier.
The using method for formula blood sugar monitoring equipment of exempting to take a blood sample, the method comprises the following steps:
A, selected several can reflect blood glucose closely position associated with human body resistance, and at these human bodies, the variation of the blood glucose value of human body can directly affect the resistance variations of this human body, and the variance values being associated equates;
B, utilize the reagent paper socket on main frame top, by reagent paper, take a blood sample, reagent paper is inserted to reagent paper socket, open blood sugar monitoring equipment, and measuring blood value a;
C, by finger-type groove, grasping handle electrode, measure the resistance value between two arms, and repeatedly measure the resistance meansigma methods b obtaining between two arms, obtain blood glucose under physical qualification now and the proportionate relationship of resistance, set its relating value t=a/b;
D, later stage are tested selected human body resistance value cn at every turn, by relating value t, obtain corresponding blood glucose value an, its account form is: an=cn*t, the each measuring resistance of human body resistance acquisition module, by microprocessor, automatically calculate, convert resistance value to blood glucose value, be presented on LCD display, for user reference;
E, because human body is different at the blood glucose value of different periods, therefore, need to determine the blood glucose standard value of different periods, in the good situation of condition, once take a blood sample and measure the benchmark blood glucose value f under above-mentioned physical qualification, wherein f utilizes the mode of blood sampling to measure blood glucose value, and this value is as the standard value of later stage change of blood sugar amplitude;
F, later stage are at every turn at above-mentioned specific time point, by exempting from blood sampling formula measurement monitoring equipment, measure the blood glucose value an1 under this condition, and by blood glucose value an1, f contrasts with standard value, change of blood sugar amplitude while drawing each measurement, this amplitude can be reminded the user change of blood sugar of every day at any time, makes in time health coordinating program;
Can autostore each blood sugar measured of g, memory module, user can be taked corresponding health conditioning according to the variation of blood glucose value.
Further, described step a human body choose the direct accuracy that affects blood glucose measurement, choose the position that human body skin is thinner, this position tight skin is affixed on vein blood vessel, the blood sugar content of vein blood vessel directly affects the skin content of chemical substances at this position, resistance and the content of chemical substances of skin are closely related, and the change of blood sugar at this position is direct cutaneous resistance also.
Further, in steps d, human body resistance acquisition module human body two ends resistance, its detection method is divided two steps, and first step Vcc voltage is determined, and voltage sample 34 times goes average AD value after maximin, by following formula:
Second step human body resistance, resistance is every 4ms once sampling, number of times is 1000 times, service time 4s, after average AD value, by following formula:
After arrangement, can draw:
measured value for human body resistance.
Beneficial effect of the present invention:
1. adopt test skin resistance to react blood sugar for human body and change, the traditional approach that need to take a blood sample while avoiding at every turn carrying out blood sugar test, alleviates patient suffering, the convenient change of blood sugar of grasping during postscript.
2. by measuring the different resistance value of human body, measure the numerical value of its blood glucose, without blood sampling, can measure blood glucose numerical value soon, facilitate more user anywhere or anytime own blood glucose to be measured, convenient and practical.
3. the present invention's formula blood sugar monitoring device just of exempting to take a blood sample is taken a blood sample first and is determined blood glucose standard value, after without taking a blood sample again, only need by measuring two end points resistance values of human body two upper limb or other two different parts, blood sugar test equipment calculates, draw current blood glucose value, be presented on LCD display.
4. the present invention's formula blood sugar monitoring equipment of exempting to take a blood sample is used simple, easy to operately, for the ailing patient who is tormented by diabetes, is able to very large help, also can accomplish the effect of monitoring for non-disease personnel simultaneously, accomplishes effective prevention.
Figure of description
Fig. 1 is the present invention's formula blood sugar monitoring equipment front schematic view of exempting to take a blood sample.
Fig. 2 is the present invention's formula blood sugar monitoring equipment schematic rear view of exempting to take a blood sample.
Fig. 3 is the grasping handle electrode enlarged drawing that wire of the present invention connects negative pole end.
Fig. 4 is the present invention's another kind of form schematic diagram of formula blood sugar monitoring equipment back side positive electricity end of exempting to take a blood sample.
Fig. 5 is blood glucose value monitoring flow chart of the present invention.
Fig. 6 is the present invention's formula blood sugar monitoring equipment schematic of exempting to take a blood sample.
Fig. 7 is inventor's bulk resistor Acquisition Circuit figure.
Fig. 8 is the demonstration modular circuit figure of LCD display of the present invention.
Fig. 9 is clock module circuit diagram of the present invention.
Figure 10 is inventor's bulk resistor collecting flowchart figure.
Figure 11 is microcontroller circuit figure of the present invention.
Labelling in accompanying drawing: main frame 1; LCD display 2; Button 3; Switch key 4; Reagent paper socket 5; Grasping handle electrode 6; Wire 7; Finger-type groove 11; Metal dots touched electrode 12; The second metal dots touched electrode 13; Electrode 61.
The specific embodiment
Embodiment 1:
Please refer to accompanying drawing 1～2, a kind of formula blood sugar monitoring equipment of exempting to take a blood sample, comprise main frame 1, be located at the pcb board in main frame 1, on described pcb board, be provided with LCD display 2, microprocessor, the blood sugar test circuit being electrically connected to microprocessor and the memory module being electrically connected to micro-processing, power module, clock module, described blood sugar test circuit comprises blood sugar test module, as shown in Figure 9, the model that clock module adopts is DS1302ZN+, as shown in figure 11, the chip model that described microprocessor adopts is MSP430FG4617.
On pcb board, also be provided with the human body resistance Acquisition Circuit being electrically connected to microprocessor, this human body resistance Acquisition Circuit comprises human body resistance acquisition module, resistance value size between 2 of described human body resistance acquisition module human body skins, and the result detecting is converted to blood glucose value size by microprocessor be presented on the LCD display 2 on main frame 1.
As shown in Fig. 2～4, under described main frame 1 shell, be covered with some finger-type grooves 11, and be provided with metal dots touched electrode 12 at each finger-type groove 11 front end, this metal dots touched electrode 12 is connected with human body resistance Acquisition Circuit is anodal.Described finger-type groove 11 is provided with three, respectively forefinger groove, middle finger groove, nameless groove, human body left index finger, middle finger, nameless Naked are pressed on finger-type groove 11, make forefinger, middle finger, unknownly tap electrode 12 with metal in groove and contact, the naked grasping handle electrode 6 of holding of right human hand, the right hand is contacted with metal electrode 61, form resistance loop.The convenient finger in groove position of finger-type groove 11 is clamped and is exempted to take a blood sample formula blood sugar monitoring equipment, human body left index finger, middle finger, nameless Naked are pressed on finger-type groove 11, thumb is pressed in the front of main frame 1, button 3, switch key 4 that can main control system 1 front, little finger can be pressed in the case surface of main frame 1 back of the body, to increase the fastening degree of hands.In order to make metal dots touched electrode 12 better and finger contact, therefore at each groove part, be provided with a metal dots touched electrode 12, this electrode can be and just also can be negatively, if be made as positive pole with this metal dots touched electrode 12,61 so other of metal electrodes are negative pole.In described main frame 1 shell side, draw a wire 7, this wire 7 is connected electrically in the negative pole of human body resistance Acquisition Circuit, and wire 7 ends connect grasping handle electrodes 6, is provided with the metal electrode 61 that a circle is connected with metal wire in wire 7 on described grasping handle electrode 6.Two handss can be controlled the formula blood sugar monitoring equipment of exempting to take a blood sample of the present invention very easily.
Embodiment 2:
As shown in Figure 4, main frame 1 back side also can be designed to unnotched form, the second metal dots touched electrode 13 need only be set at main frame 1 back side, this touched electrode can cover the subregion at main frame 1 back side, but the resistance that this metal dots touched electrode 13 itself is produced is negligible, avoid occurring larger error in the middle of monitoring.
Embodiment 3:
As shown in Fig. 5～8 and Figure 10, the using method of a kind of formula blood sugar monitoring equipment of exempting to take a blood sample of the present invention, the method comprises the following steps:
A, selected several can reflect blood glucose closely position associated with human body resistance, at these human bodies, the variation of the blood glucose value of human body can directly affect the resistance variations of this human body, and the variance values being associated equates, choosing human body resistance association closely behind position, as left hand, the right hand, by foregoing description to exempt from the formula blood sugar monitoring equipment of taking a blood sample known, the forefinger of left hand, middle finger, the whole hands palm of the hand of the third finger and the right hand is the contact point as resistance test, and because everyone hand sweat gland secretion is inconsistent, cause hands and metal to contact effect also different, can have influence on the accuracy of test.Therefore,, before test, need to, with the clean tested position of ethanol, make it to keep clean.Human body choose the direct accuracy that affects blood glucose measurement, choose the position that human body skin is thinner, this position tight skin is affixed on vein blood vessel, the blood sugar content of vein blood vessel directly affects the skin content of chemical substances at this position, resistance and the content of chemical substances of skin are closely related, and the change of blood sugar at this position is direct cutaneous resistance also.
B, the present invention need to take a blood sample first, utilize the reagent paper socket 5 on main frame 1 top, by reagent paper, take a blood sample, reagent paper is inserted to reagent paper socket 5, open blood sugar monitoring equipment, and measuring blood value a, for example this value is 5.5mmol/L, during this value of general test, need human body to measure healthy in the situation that, and this value will divide ante cibum and after meal, ante cibum is owing to having taken in food, general food all can have sugary composition, can have influence on the blood sugar concentration in blood.Test this standard value and be for later stage test blood glucose value and this are worth to compare, judge that whether measured is in health status.
C, the resistance value of measuring between two arms by finger-type groove 11, grasping handle electrode 6, and repeatedly measure the resistance meansigma methods b obtaining between two arms, as obtain blood glucose under physical qualification now and the proportionate relationship of resistance, set its relating value t=a/b; Human body resistance is mainly skin resistance, and the cuticular resistance that epidermis 0.05～0.2mm is thick is very large, and during xerosis cutis, human body resistance is about 6～10k Ω, even up to 100k Ω; But horny layer is easily destroyed, removes cuticular skin resistance and be about 800～1200 Ω; Therefore, from this, also can find out, in step a, with ethanol, clean the importance at tested position.Suppose that the resistance meansigma methods between two arms is 5K Ω, i.e. t=a/b=5.5mmol/L/5K Ω=1.1mmol/LK Ω.
D, the selected human body resistance value cn of each test of later stage, as get 5.5K Ω, by relating value t, obtain corresponding blood glucose value an, its account form is: an=cn*t=5.5K Ω * 1.1mmol/LK Ω=6.05mmol/L, the each measuring resistance of human body resistance acquisition module, by microprocessor, automatically calculate, convert resistance value to blood glucose value, be presented on LCD display 2, for user reference, because the figure place showing on LCD display 2 is to be accurate to 0.1, therefore, show value on LCD display 2 is 6.1mmol/L, 6.1mmol/L standard value 5.5mmol/L has before exceeded 0.6mmol/L.Therefore, user, when knowing these data, should be noted that the diet of oneself, allows oneself when testing next time, can reach near standard value.
E, because the blood glucose value of before or after meals is different, therefore, need to determine ante cibum and blood glucose standard value after meal, in the good situation of condition, once take a blood sample and measure benchmark AC Sugar value f under above-mentioned physical qualification and the benchmark under above-mentioned physical qualification blood glucose value g after meal, wherein, f, g utilize the mode of blood sampling to measure blood glucose value, and these two values are as the standard value of later stage change of blood sugar amplitude;
F, later stage are at every turn at above-mentioned specific time point, under ante cibum condition, as 12:00 at noon, by exempting from blood sampling formula measurement monitoring equipment, measure the blood glucose value an1 under this condition, and by blood glucose value an1, f contrasts with standard value, the change of blood sugar amplitude while drawing each measurement, this amplitude can be reminded the user change of blood sugar of every day at any time, makes in time health coordinating program;
G, later stage are at every turn at above-mentioned specific time point, after meal under condition, as 16:00 in afternoon, by exempting from blood sampling formula measurement monitoring equipment, measure the blood glucose value an2 under this condition, g contrasts with standard value, change of blood sugar amplitude while drawing each measurement, this amplitude can be reminded the user change of blood sugar of every day at any time, makes in time health coordinating program;
Can autostore each blood sugar measured of h, memory module, user can be taked corresponding health conditioning according to the variation of blood glucose value.
By following table can find out someone ante cibum blood glucose value in one week change:
In upper table, can find out, in ante cibum, test, from Monday to Thursday, be all to continue to raise, this rising is a kind of bad phenomenon, although since Friday, decline, but still rise with standard value 5.1, therefore, still need to keep on a diet, keep good dietary habit.
Because standard value is generally higher after meal, therefore, when declining to some extent, when fall is little, user can not need to do specific aim conditioning, only need press normal diet just can, but when improving, will nurse one's health diet work is suitable.Test is after meal identical with test ante cibum, monitors the blood glucose value size of health, and do not need as traditional blood glucose meter by the data variation of this every day, all goes to take a blood sample to test at every turn, saves time, and also reduces many miseries.
In addition, be exactly the blood sugar monitoring of the higher person of blood glucose and diabetics in addition, as following table:
The standard value of blood glucose is between 6.1～6.9, from upper table, can find out, belong to a region that is about to suffer from diabetes, belong to sub-health state, therefore, once be found in the lasting situation about raising of blood glucose, must make dietetic regulation, or check to regular hospital, prevent the generation of diabetes, from this aspect, can find out, the effect of the formula blood sugar monitoring equipment of exempting to take a blood sample of the present invention is very large.
Upper table is to suffer from diabetics monitoring result, from upper table, can find out, the blood glucose value of this sufferer is higher than standard value, illustrates that blood glucose rises lasting, therefore, need to go to see a doctor as early as possible, prevents dangerous situation.From this, also can find out, the formula blood sugar monitoring equipment of exempting to take a blood sample of the present invention has forewarning function.
In steps d, human body resistance acquisition module human body two ends resistance, its detection method is divided two steps, and first step Vcc voltage determines, and as shown in figure 11, No. 23 pin samplings 34 times, go average AD value after maximin, by following formula:
Second step human body resistance, as shown in figure 11, No. 21 pins are every 4ms once sampling, number of times is 1000 times, service time 4s, after average AD value, by following formula:
After arrangement, can draw:
for the measured value of human body resistance, from this formula, can find out, Vcc is generally constant, and AD value is larger, R
human bodybe worth less, otherwise AD value is less, R
human bodybe worth greatlyr, then by formula blood glucose value an=cn*t, cn is the R in above-mentioned formula
human bodyresistance, blood glucose value an is with R
human bodyresistance increase and raise.
Embodiment 4:
With the tight human body choosing method of blood glucose value, human body choose the direct accuracy that affects blood glucose measurement, choose the position that human body skin is thinner, this position tight skin is affixed on vein blood vessel (comprising blood capillary), the blood sugar content of vein blood vessel directly affects the skin content of chemical substances at this position, resistance and the content of chemical substances of skin are closely related, and the change of blood sugar at this position is direct cutaneous resistance also.For example, choose human body left index finger top the first joint skin, human body left index finger bottom the first joint skin, the third finger the first joint skin etc. that keeps left of keeping right of keeping right, these human body skins are all relatively near vein blood vessel (blood capillary).Epidermis processing method before test: adopt alcohol disinfecting more than 30 seconds, make to test skin epidermis position temperature, humidity, salinity etc. and reach stable test environment, can also with in cycle carry out chafe, to obtain normal impedance response.
Embodiment 5:
As shown in Figure 7, Fig. 7 is inventor's bulk resistor Acquisition Circuit figure, this circuit adopts LM358P dual operational amplifier, stability is high, price is also cheap, this chip by two independently high gain operational amplifier form, this circuit can arrive single supply work within the scope of the supply voltage of 32v at 3v, also can under dual power supply condition, work alone, and there is the effect of internal frequency compensation, No. 3 pins of LM358P dual operational amplifier are connected on J1 trigger, No. 1 pin connects the resistance R 3 that resistance is 1K in turn, capacitor C 15-104, No. 8 pin connects capacitor C 14-104, on No. 3 pins, also connect R13-51KF, R13-51KF ground connection, R13-51KF earth terminal is connected with No. 1 leads ends the R13-10KF connecting, R14-100KF, No. 2 pin is connected to R13-10KF, between R14-100KF.
Embodiment 6:
As shown in Figure 8, Fig. 8 is the demonstration modular circuit figure of LCD display of the present invention, in circuit, being connected with model is the display screen of LCD1602A, No. 3 pins of this LCD1602A display screen are electrically connected to variable resistance VR1-510K, No. 15 pin is electrically connected to resistance R 12-100K, No. 16 pin is electrically connected to an audion Q1-8050, audion Q1-8050 negative electricity contact resistance R10-10K.
Embodiment 7:
As shown in Figure 9, Fig. 9 is clock module circuit diagram of the present invention, in clock module circuit, be connected with clock chip DS1302ZN+, DS1302 ZN+ is a kind of high-performance, low-power consumption, with the real time clock circuit of RAM, it can to year, month, day, Sunday, time, minute, second carries out timing, have leap year compensate function, running voltage is 2.5V～5.5V.Adopt three-wire interface and CPU to carry out synchronous communication, and can adopt burst mode once to transmit clock signal or the RAM data of a plurality of bytes.There is the ram register for provisional store data of 31 * 8 DS1302 inside.DS1302 is the upgrading products of DS1202, compatible with DS1202, but has increased main power source/back-up source dual power supply pin, and the ability of back-up source being carried out to the thin current charges of tiny stream is provided simultaneously.
Embodiment 8:
As shown in figure 11, Figure 11 is microcontroller circuit figure of the present invention, this microprocessor model is that the chip model that described microprocessor adopts is MSP430FG4617, it is 1 years old, 2, No. 3 pins connect respectively main frame 1 front, be positioned at three buttons 3 of LCD display below, No. 32 pin connecting valve buttons 4, 5, No. 6 pin connects storage chip, this storage chip model is IC-24C02, No. 4 pins are contact resistance R1-1K in turn, light sensitive diode D1, light sensitive diode D1 other end ground connection, No. 23 line connects divider resistance R5-510KF, R6-510KF, capacitor C 11-104 is in parallel with resistance R 6-510KF, human body resistance Acquisition Circuit can calculate the resistance value size at human body two ends by this part divider resistance.
The foregoing is only the preferred embodiment of the present invention; not thereby limit the scope of the claims of the present invention; every equivalent structure or conversion of equivalent flow process that utilizes description of the present invention and accompanying drawing content to do; or be directly or indirectly used in other relevant technical field, be all in like manner included in scope of patent protection of the present invention.
Claims (8)
1. the formula blood sugar monitoring equipment of exempting to take a blood sample, comprise main frame (1), be located at the pcb board in main frame (1), on described pcb board, be provided with LCD display (2), microprocessor, the blood sugar test circuit being electrically connected to microprocessor and the memory module being electrically connected to micro-processing, power module, clock module, described blood sugar test circuit comprises blood sugar test module, it is characterized in that: on pcb board, also be provided with the human body resistance Acquisition Circuit being electrically connected to microprocessor, this human body resistance Acquisition Circuit comprises human body resistance acquisition module, resistance value size between 2 of described human body resistance acquisition module human body skins, and the result detecting is converted to blood glucose value size by microprocessor be presented on the LCD display (2) on main frame (1).
2. a kind of formula blood sugar monitoring equipment of exempting to take a blood sample according to claim 1, it is characterized in that: under described main frame (1) shell, be covered with some finger-type grooves (11), and being provided with metal dots touched electrode (12) at each finger-type groove (11) front end, this metal dots touched electrode (12) is connected with human body resistance Acquisition Circuit is anodal.
3. a kind of formula blood sugar monitoring equipment of exempting to take a blood sample according to claim 1, it is characterized in that: in described main frame (1) shell side, draw a wire (7), this wire (7) is connected electrically in the negative pole of human body resistance Acquisition Circuit, wire (7) end connects grasping handle electrode (6), is provided with the metal electrode (61) that the circle metal wire interior with wire (7) is connected on described grasping handle electrode (6).
4. a kind of formula blood sugar monitoring equipment of exempting to take a blood sample according to claim 2, it is characterized in that: described finger-type groove (11) is provided with three, respectively forefinger groove, middle finger groove, nameless groove, human body left index finger, middle finger, nameless Naked are pressed on finger-type groove (11), make forefinger, middle finger, the third finger tap electrode (12) with metal in groove and contact, the naked grasping handle electrode (6) of holding of right human hand, makes the right hand contact with metal electrode (61), forms resistance loop.
5. a kind of formula blood sugar monitoring equipment of exempting to take a blood sample according to claim 1, is characterized in that: in described human body resistance Acquisition Circuit, be connected with dual operational amplifier.
With claim 1 exempt to take a blood sample the using method of formula blood sugar monitoring equipment, it is characterized in that, the method comprises the following steps:
A, selected several can reflect blood glucose closely position associated with human body resistance, and at these human bodies, the variation of the blood glucose value of human body can directly affect the resistance variations of this human body, and the variance values being associated equates;
B, utilize the reagent paper socket (5) on main frame (1) top, by reagent paper, take a blood sample, reagent paper is inserted to reagent paper socket (5), open blood sugar monitoring equipment, and measuring blood value a;
C, by finger-type groove (11), grasping handle electrode (6), measure the resistance value between two arms, and repeatedly measure the resistance meansigma methods b obtaining between two arms, obtain blood glucose under physical qualification now and the proportionate relationship of resistance, set its relating value t=a/b;
D, later stage are tested selected human body resistance value cn at every turn, by relating value t, obtain corresponding blood glucose value an, its account form is: an=cn*t, the each measuring resistance of human body resistance acquisition module, by microprocessor, automatically calculate, convert resistance value to blood glucose value, be presented at LCD display (2) upper, for user reference;
E, because human body is different at the blood glucose value of different periods, therefore, need to determine the blood glucose standard value of different periods, in the good situation of condition, once take a blood sample and measure the benchmark blood glucose value f under above-mentioned physical qualification, wherein f utilizes the mode of blood sampling to measure blood glucose value, and this value is as the standard value of later stage change of blood sugar amplitude;
F, later stage are at every turn at above-mentioned specific time point, by exempting from blood sampling formula measurement monitoring equipment, measure the blood glucose value an1 under this condition, and by blood glucose value an1, f contrasts with standard value, change of blood sugar amplitude while drawing each measurement, this amplitude can be reminded the user change of blood sugar of every day at any time, makes in time health coordinating program;
Can autostore each blood sugar measured of g, memory module, user can be taked corresponding health conditioning according to the variation of blood glucose value.
7. the using method of the formula blood sugar monitoring equipment of exempting to take a blood sample according to claim 6, it is characterized in that: described step a human body choose the direct accuracy that affects blood glucose measurement, choose the position that human body skin is thinner, this position tight skin is affixed on vein blood vessel, the blood sugar content of vein blood vessel directly affects the skin content of chemical substances at this position, resistance and the content of chemical substances of skin are closely related, and the change of blood sugar at this position is direct cutaneous resistance also.
8. the using method of the formula blood sugar monitoring equipment of exempting to take a blood sample according to claim 6, it is characterized in that: in steps d, human body resistance acquisition module human body two ends resistance, its detection method is divided two steps, first step Vcc voltage is determined, voltage sample 34 times, goes average AD value after maximin, by following formula:
Vcc=
=Vcc=
；
Second step human body resistance, resistance is every 4ms once sampling, number of times is 1000 times, service time 4s, after average AD value, by following formula:
；
After arrangement, can draw:
; R
human bodymeasured value for human body resistance.
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| CN201410418223.XA CN104188662A (en) | 2014-08-22 | 2014-08-22 | Blood-sampling-free type blood sugar monitoring device and use method thereof |
| TW103132344A TW201607509A (en) | 2014-08-22 | 2014-09-19 | Bloodless glucose measuring device and method of use |
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| CN104783763A (en) * | 2015-04-23 | 2015-07-22 | 天津中医药大学 | Probe used for detecting human skin temperature, humidity and resistance |
| CN105011946A (en) * | 2015-07-22 | 2015-11-04 | 通普生物科技（北京）有限公司 | Method for measuring value of blood glucose |
| CN106985950A (en) * | 2017-05-05 | 2017-07-28 | 成都步共享科技有限公司 | A kind of intelligent vehicle handle for being used to share bicycle |
| CN116172552A (en) * | 2023-03-03 | 2023-05-30 | 上海睿触科技有限公司 | Noninvasive glucometer and blood glucose detection method |
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| CN104783763A (en) * | 2015-04-23 | 2015-07-22 | 天津中医药大学 | Probe used for detecting human skin temperature, humidity and resistance |
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| CN116172552B (en) * | 2023-03-03 | 2024-03-22 | 上海睿触科技有限公司 | Noninvasive glucometer and blood glucose detection method |
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| TW201607509A (en) | 2016-03-01 |
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Application publication date: 20141210 |