CN104173704A - Traditional Chinese medicine decoction for treating subacute thyroiditis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine decoction for treating subacute thyroiditis. The traditional Chinese medicine decoction is prepared from the following Chinese medicinal raw materials in parts by weight: 10g of honeysuckle, 10g of chrysanthemum, 6g of mint, 10g of schizonepeta, 10g of radix angelicae, 6g of felwort, 10g of cape jasmine, 10g of radix bupleuri, 10g of scutellaria baicalensis, 15g of radix rehmanniae, 15g of radix paeoniae rubra, 10g of cortex moutan, 10g of ligusticum wallichii, 15g of angelica sinensis, 10g of pollen typhae, 15g of thunberg fritillary bulb, 9g of airpotato yam, 15g of selfheal, 15g of radix paeoniae alba, 15g of astragalus membranaceus, 6g of bighead atractylodes rhizome and 6g of rhizoma cimicifugae. The selected raw materials have the efficacies of clearing away heat and toxic materials, soothing the liver and purging fire, and softening hardness to dissipate stagnation by dialectic combination, has a significant curative effect on the subacute thyroiditis, and is worthy of further clinical promotion.

Description

A kind of Chinese medicine decoction for the treatment of subacute thyroiditis

Technical field

The present invention relates to a kind of Chinese medicine decoction for the treatment of subacute thyroiditis.

Background technology

Thyroid inflammation due to the allergy that subacute thyroiditis system is caused by virus or virus.With acute upper respiratory tract infection symptom companion thyroid anthorisma, or only there is thyroid position to occur that tuberosity lump is main clinical characteristics, show as heating, pharyngalgia, cervical region dull pain or severe pain, or emit to lower jaw, occipitalia or chest, minority is Silent Neuritis goiter.Typical case's course of disease is roughly divided into early stage companion's hyperthyroidism, occurs of short duration hypothyroidism performance mid-term, and convalescent period.Primary disease is more common in the women between 20～30 years old, belongs to self-limited disease, has tendency of recurrence.The treatments such as the conventional nonsteroidal of Western medicine and glucocorticoid, heating is often alleviated very soon, but relapse rate is high, and administration time has been grown and has been had many untoward reaction, as hypertension, edema, moon face etc.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine decoction for the treatment of subacute thyroiditis.

The technology used in the present invention solution is:

Treat a Chinese medicine decoction for subacute thyroiditis, it is that raw material of Chinese medicine by following weight portion is made: Flos Lonicerae 10g, Flos Chrysanthemi 10g, Herba Menthae 6g, Herba Schizonepetae 10g, Radix Angelicae Dahuricae 10g, Radix Gentianae 6g, Fructus Gardeniae 10g, Radix Bupleuri 10g, Radix Scutellariae 10g, Radix Rehmanniae 15g, Radix Paeoniae Rubra 15g, Cortex Moutan 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 15g, Pollen Typhae 10g, Bulbus Fritillariae Thunbergii 15g, Rhizoma Dioscoreae Bulbiferae 9g, Spica Prunellae 15g, Radix Paeoniae Alba 15g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Cimicifugae 6g.

Above-mentioned Chinese medicine decoction can be prepared as follows: the raw material of Chinese medicine of above-mentioned weight portion is put into drug-decocting appliance in the lump, add the clean water that meets drinking water standard, amount of water is advisable to surpass liquid level 2～3cm; Enter to decoct and front above-mentioned raw material of Chinese medicine is soaked to half an hour, make it fully moistening, fully fried in order to medicine juice; Then (suddenly) fire of useing force boils, then uses literary composition (micro-) fire instead and decoct.When decocting about 15 minutes, every dose stops while decocting into 180-200 milliliter medicine juice, removes medicinal residues, gets decoction.

Pharmacology of the present invention and effect are as follows:

Subacute thyroiditis is clinical common a kind of endocrinopathy, belongs to the categories such as the traditional Chinese medical science " wart is swollen ", " goiter ", often because clinical symptoms is complicated by mistaken diagnosis, thereby delays treatment, thereby makes many conditions of patients protracteds course of disease.Motherland's medical science early has discussion to this, a < < Yizong Jinjian > > surgery goiter piece of writing is pointed out: " wart person is as tassel; the shape of network; thus wart person with gas keep here be name also, many diseases caused by exogenous pathogenic factor six evils, the four stages in the course of an epidemic febrile disease is solidifying strongly fragrant; endogenous cause of ill seven emotions melancholy Gui anger; the damp-phlegm stasis of blood is stagnant, and middle haze aqueous vapor forms, and all mends sufferings ".Applicant is according to clinical experience for many years, think that the generation of this disease is how for a long time strongly fragrant not smooth because of feelings will, plain bromhidrosis is empty in addition, failure of defensive QI to protect the body against pathogen, the evil poison of diseases caused by exogenous pathogenic factor is taken advantage of a weak point in opponent's defence and is invaded, cause evil poison, the stagnation of QI, blood stasis and hand over resistance to form, therefore there is heating, throat swell thing or pain, irritated irritability, weak, red tongue with thin and yellow fur, wiry and frequent pulse etc., treatment should adopt the methods such as heat-clearing and toxic substances removing, soothing liver-QI pathogenic fire purging, hard masses softening and resolving.Flos Lonicerae in decoction of the present invention, Flos Chrysanthemi, Herba Menthae, Herba Schizonepetae, Radix Angelicae Dahuricae heat-clearing and toxic substances removing dispelling wind pathogens, the soothing liver-QI pathogenic fire purging promoting blood circulation and cooling bloods such as Radix Gentianae, Fructus Gardeniae, Radix Bupleuri, Radix Scutellariae, the Radix Rehmanniae, Radix Paeoniae Rubra, Cortex Moutan, Pollen Typhae, above-mentioned two class medicines have the effect of antiviral, sterilization; The heat clearing away hard masses softening and resolving such as Bulbus Fritillariae Thunbergii, Rhizoma Dioscoreae Bulbiferae, Spica Prunellae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cimicifugae are with tonifying Qi and lifting yang Gu Wei, and the Radix Rehmanniae wherein, Cortex Moutan have the effect that regulates hypothalamus hypothalamic pituitary adrenal axis, anti-immunization, Radix Angelicae Sinensis, Rhizoma Chuanxiong have anticomplementary, anti-immune effect, and the Radix Paeoniae Alba has the effect of the easing the affected liver of enriching blood.So patient coordinates we's treatment, symptom, sign disappear or alleviate obviously, and it is very fast that laboratory examination recovers.Therefore clinic is further promoted.

Clinical data:

Choose in January, 2010-2014 and go to a doctor in the department of Chinese medicine outpatient service subacute thyroiditis patient of Qingdao Shi Huangdao Qu Zhong Yi Yuan 86 examples year March, be divided at random two groups and treat, treatment group 43 examples wherein, matched group 45 examples; Matched group conventional application nonsteroidal and glucocorticoid are treated, and treatment group adds with decoction treatment of the present invention on the treatment basis of matched group.1 month course for the treatment of.

Clinical efficacy

Statistical method has carried out date processing with SPSS10.0 statistical software.Data represent with means standard deviation.Between two groups, relatively adopt t check, the relatively employing X 2 test of rate.P < 0.05 has statistical significance for difference.

Result: treatment group is compared with matched group, treatment group cure rate and improvement rate are all higher than matched group, there is significant difference (P < 0.05), illustrate that treatment group adds with decoction treatment subacute thyroiditis of the present invention on the basis of matched group evident in efficacy, be worth further clinical expansion.

Model case:

Case 1

Xue, female, 50 years old, May 10 2011 first visit date.Main suit: heating companion swells and ache 2 days in throat.History of present illness: patient occurred heating without obvious cause before 2 days, pharyngeal discomfort, swelling and ache in throat, is in and takes cold relief capsule without being clearly better, therefore examine.Personality was irritable usually in the past.Inscribe and see: flushed complexion, dysphoria, heating, pharynx is red and swollen, the throat thing that swells, tenderness is obvious, reddish tongue yellow and thin fur, floating and rapid pulse.Have a medical check-up: T38.6 ℃ of pharyngeal congestion is obvious, tonsil is without enlargement, ° enlargement of right thyroid II, and matter is slightly hard, and tenderness is obvious, vascular-less noise.Two pulmonary respiration sounds are thick, do not hear and dry moist rales, and 88 beats/min of hearts rate, restrain regularly, and abdomen is soft without tenderness, and two lower limb are without edema.The heavy 38mm/h that has a blood test, routine blood test is without extremely, thyroid function: T3:6.9pmol/L T4:25.1mol/L TSH:0.23 uIU/ml.Western medicine diagnose: subacute thyroiditis; Tcm diagnosis: wart is sick; Pathogenesis: pathogenic fire derived from stagnation of liver-QI, pyretic toxicity is invaded outward, and evil poison, the stagnation of QI, blood stasis are handed over resistance throat; The rule for the treatment of: heat-clearing and toxic substances removing, soothing liver-QI pathogenic fire purging, hard masses softening and resolving.Side's medicine: decoction of the present invention, potion, divided and sooner or later took every day, take medicine after one week, heating disappears, the swollen thing in throat reduces, and pharyngalgia alleviates, stool is slightly dry, the place ahead adds Radix Et Rhizoma Rhei 6 g with purging heat to relax the bowels, continues to take 5 doses, takes afterwards and examines, symptom disappears substantially, require Chinese patent drugs for treatment, give danzhi xiaoyao pills to consolidate curative effect, heavy, the thyroid function of having a blood test after January recovers normal.

Case 2

Xiao, female, 23 years old, in June, 2013 on first visit date.Main suit: generate heat 1 week, throat pain 2 days.History of present illness: occur heating after patient is angry before 1 week, tired, pharyngalgia, takes an antipyretic, antibiotic medicine (specifically not quite clear) certainly, and heating alleviates, and occurs throat pain before 2 days, has swollen thing, therefore examine.Inscribe and see: heating, pharynx is red and swollen, the throat thing that swells, tenderness, even cough but no phlegm, red tongue with thin and yellow fur, wiry and frequent pulse.Have a medical check-up: T37.3 ℃ of pharyngeal mild hyperaemia, bilateral amygdala is without enlargement, ° enlargement of bilateral thyroid I, matter is tough, tenderness, two pulmonary respiration sounds are thick, do not hear and dry moist rales, and 70 beats/min of hearts rate, restrain regularly, and abdomen is soft without tenderness, and two lower limb are without edema.The heavy 28mm/h that has a blood test, routine blood test is without extremely, and thyroid function is without extremely.Western medicine diagnose: subacute thyroiditis; Tcm diagnosis: wart is sick; Pathogenesis: stagnation of QI due to depression of the liver, pyretic toxicity is invaded outward, and evil poison, the stagnation of QI, blood stasis are handed over resistance throat; The rule for the treatment of: heat-clearing and toxic substances removing, liver-smoothing, qi-regulating pathogenic fire purging, hard masses softening and resolving.Side's medicine: top decoction adds Pericarpium Citri Reticulatae Viride 10 g, Radix Peucedani 10 g, took after one week, and heating disappears, and throat pain and cough obviously alleviate, and continued to take 7 doses, the place ahead and examined afterwards, and the swollen thing in throat disappears.Advise patient to note at ordinary times regulating oneself emotion, strong taking exercises, rule of life, strikes a proper balance between work and rest.Follow up a case by regular visits to afterwards and have no recurrence.

The specific embodiment

Treat a Chinese medicine decoction for subacute thyroiditis, it is that raw material of Chinese medicine by following weight portion is made: Flos Lonicerae 10g, Flos Chrysanthemi 10g, Herba Menthae 6g, Herba Schizonepetae 10g, Radix Angelicae Dahuricae 10g, Radix Gentianae 6g, Fructus Gardeniae 10g, Radix Bupleuri 10g, Radix Scutellariae 10g, Radix Rehmanniae 15g, Radix Paeoniae Rubra 15g, Cortex Moutan 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 15g, Pollen Typhae 10g, Bulbus Fritillariae Thunbergii 15g, Rhizoma Dioscoreae Bulbiferae 9g, Spica Prunellae 15g, Radix Paeoniae Alba 15g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Cimicifugae 6g.

The preparation method of above-mentioned Chinese medicine decoction is as follows: the raw material of Chinese medicine of above-mentioned weight portion is put into drug-decocting appliance in the lump, add the clean water that meets drinking water standard, amount of water is advisable to surpass liquid level 2～3cm; Enter to decoct and front above-mentioned raw material of Chinese medicine is soaked to half an hour, make it fully moistening, fully fried in order to medicine juice; Then (suddenly) fire of useing force boils, then uses literary composition (micro-) fire instead and decoct.When decocting about 15 minutes, every dose stops while decocting into 180-200 milliliter medicine juice, removes medicinal residues, gets decoction.

Claims (1)

1. treat a Chinese medicine decoction for subacute thyroiditis, it is characterized in that it is that raw material of Chinese medicine by following weight portion is made: Flos Lonicerae 10g, Flos Chrysanthemi 10g, Herba Menthae 6g, Herba Schizonepetae 10g, Radix Angelicae Dahuricae 10g, Radix Gentianae 6g, Fructus Gardeniae 10g, Radix Bupleuri 10g, Radix Scutellariae 10g, Radix Rehmanniae 15g, Radix Paeoniae Rubra 15g, Cortex Moutan 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 15g, Pollen Typhae 10g, Bulbus Fritillariae Thunbergii 15g, Rhizoma Dioscoreae Bulbiferae 9g, Spica Prunellae 15g, Radix Paeoniae Alba 15g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Cimicifugae 6g.