CN104147378A - Traditional Chinese medicine composition for treating blood-vacuity and wind-dryness type psoriasis - Google Patents
Traditional Chinese medicine composition for treating blood-vacuity and wind-dryness type psoriasis Download PDFInfo
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- CN104147378A CN104147378A CN201410346837.1A CN201410346837A CN104147378A CN 104147378 A CN104147378 A CN 104147378A CN 201410346837 A CN201410346837 A CN 201410346837A CN 104147378 A CN104147378 A CN 104147378A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating blood-vacuity and wind-dryness type psoriasis, and relates to the field of traditional Chinese medicines. The composition is prepared from the following raw materials in parts by weight: 5-14 parts of polygonum multiflorum, 7-12 parts of arillus longan, 13-17 parts of suberect spatholobus stem, 6-12 parts of mulberry, 3-8 parts of herba schizonepetae, 5-13 parts of polygonatum kingianum, 3-8 parts of dendrobium, 12-20 parts of ventilago leiocarpa benth, 12-20 parts of ardisia punctata and 12-20 parts of embelia parviflora. The traditional Chinese medicinal composition can be mixture, granules or capsules, and is a modern preparation which has the effects of nourishing blood and dispelling wind, moistening dryness and relieving itching, has the advantages of exact curative effect, stable preparation, controllable quality and no toxic or side effect when used for treating the blood-vacuity and wind-dryness type psoriasis and can be easily widely applied.
Description
Technical field
The present invention relates to the field of Chinese medicines, especially one is treated the psoriasic Chinese medicine composition of blood-deficiency and wind-dry type.
Background technology
Psoriasis has another name called psoriasis, is a kind of chronic erythroderma desquamativum of common and easy recurrence.Psoriasic basic lesions, for having distinctive silvery white squama erythema, with extremity, scalp, northern common, mostly is the heavy summer in winter light, and psoriasis is found in from childhood to old all age group, and men and women falls ill without big-difference.Along with deepening continuously that Chinese medicine is familiar with for psoriasis pathogenesis, modern age, each middle doctor was according to its skin lesion feature, was substantially divided into 4 types: i.e. blood heat wind-dryness type, blood-deficiency and wind-dry type, blood-dryness type, blood stasis type.
Wherein, blood-deficiency and wind-dry type psoriasis is more common in psoriasic catagen.This type lesions of patients is not healed for a long time, the cloudy consumption wound of gas, deficiency of qi and blood, xerosis cutis, coarse, thicken, often with dizziness, cardiopalmus, insomnia, forgetful, pale tongue or light red, the symptoms such as white and thin fur.
At present, blood-deficiency and wind-dry type psoriasis can be cured.The traditional Chinese medical science thinks that heat in blood is its main contributor, and heat in blood be formed with many factors, can be because of internal injury caused by excess of seven emotions, mechanism of qi harmony is stagnant, strongly fragrant fire-transformation of a specified duration, so that hyperactivity of heart-fire, scorchingly hot volt in nutrient blood; Or because of intemperance of taking food, surfeit raw meat starts the thing of wind, taste are become estranged, functional activity of QI being not smooth, and strongly fragrant heat-transformation of a specified duration, multiple wind-engaging pyretic toxicity is evil and sick, rubescent speckle of hot harmony blood network, erythra desquamation of the dry Sheng failure of skin and muscle to be nourished of wind heat, Se Bai and itching; If Tianjin liquid that burns is taken in sick cloudy blood in-fighting of a specified duration by force, dry the and difficult honor of blood depletion in outside; Qi-blood disharmony, channels intercepts failure of skin and muscle to be nourished; If intense heat in the blood, evil outer the attacking of poison, steams the skin that burns, intense heat in both QI and blood systems, and stagnated fire is fled, and stagnant skin, forms Folium Styracis Suberifoliae.And with the passing of time blood-deficiency and wind-dry type psoriasis belongs to wind-dryness, impairment of YIN hematozemia or be the people of blood deficiency usually, control should nourishing YIN and benefiting blood moisturize, heat-clearing and toxic substances removing.
Summary of the invention
The object of the present invention is to provide one to treat the psoriasic Chinese medicine composition of blood-deficiency and wind-dry type, this Chinese medicine composition has good curative effect in treatment blood-deficiency and wind-dry type psoriasis.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is:
It comprises the raw material of following parts by weight: 5 parts～14 parts of Radix Polygoni Multiflori, 7 parts～12 parts of Arillus Longans, 13 parts～17 parts of Caulis Spatholobis, 6 parts～12 parts, Fructus Mori, 3 parts～8 parts of Herba Schizonepetae, 5 parts～13 parts of Rhizoma Polygonatis, 3 parts～8 parts of Herba Dendrobiis, 12 parts～20 parts of Radix seu Caulis Verntilaginis Leiocarpae, 12 parts～20 parts of 12 parts～20 parts of blood parties and Radix seu Caulis Embeliae Parviflorae.
In technique scheme, scheme is more specifically: the parts by weight of raw material are: 9 parts of Radix Polygoni Multiflori, 9 parts of Arillus Longans, 12 parts of Caulis Spatholobis, 9 parts, Fructus Mori, 5 parts of Herba Schizonepetae, 9 parts of Rhizoma Polygonatis, 6 parts of Herba Dendrobiis, 15 parts of Radix seu Caulis Verntilaginis Leiocarpae, 15 parts of 15 parts of blood parties and Radix seu Caulis Embeliae Parviflorae;
Further: the parts by weight of raw material are: 5 parts of Radix Polygoni Multiflori, 7 parts of Arillus Longans, 17 parts of Caulis Spatholobis, 12 parts, Fructus Mori, 3 parts of Herba Schizonepetae, 5 parts of Rhizoma Polygonatis, 8 parts of Herba Dendrobiis, 12 parts of Radix seu Caulis Verntilaginis Leiocarpae, 12 parts of 12 parts of blood parties and Radix seu Caulis Embeliae Parviflorae;
Further: the parts by weight of raw material are: 14 parts of Radix Polygoni Multiflori, 12 parts of Arillus Longans, 13 parts of Caulis Spatholobis, 6 parts, Fructus Mori, 8 parts of Herba Schizonepetae, 13 parts of Rhizoma Polygonatis, 3 parts of Herba Dendrobiis, 20 parts of Radix seu Caulis Verntilaginis Leiocarpae, 20 parts of 20 parts of blood parties and Radix seu Caulis Embeliae Parviflorae.
Further, the psoriasic Chinese medicine composition of this treatment blood-deficiency and wind-dry type is made mixture, granule or capsule.
Radix Polygoni Multiflori in the present invention, has tonifying liver, and kidney tonifying nourishes blood, and the effect of dispeling the wind, cures mainly hepatic and renal YIN deficiency, and sending out must be early white, blood deficiency dizziness, and waist knee joint weakness, muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids etc.
Arillus Longan in the present invention is the aril of sapindaceous plant Arillus Longan, has another name called Fructus Alpiniae Oxyphyllae, sweet spleen, Arillus Longan; The traditional Chinese medical science is thought, Arillus Longan sweet in the mouth, warm in nature enters the heart, spleen channel, there is invigorating the heart and spleen, nourish blood allay excitement, the effect such as invigorating the spleen to arrest diarrhea, inducing diuresis to remove edema, be applicable to the diseases such as body void, blood deficiency and yellow complexion, insufficiency of vital energy and blood, neurasthenia, severe palpitation, forgetful insomnia after being ill.
Caulis Spatholobi in the present invention has the promoting the circulation of blood of enriching blood, effect of the meridian dredging.
Fructus Mori nourishing YIN and supplementing blood in the present invention, the effect of promoting the production of body fluid and moisturizing, cures mainly the diseases such as having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence.
Herba Schizonepetae in the present invention has dispels the wind, induce sweat, and rash, effect of hemostasis, is applicable to flu, headache, measles, rubella, skin infection is from the beginning of waiting disease.
Rhizoma Polygonati sweet in the mouth in the present invention, property is flat; Have nourishing kidney lung moistening, effect of invigorating the spleen and replenishing QI, is applicable to lung-dryness syndrome due to deficiency of YIN, and dry cough expectorant is few, the polydipsia of quenching one's thirst, weakness of the spleen and stomach, deficiency of spleen-QI or deficiency of spleen-YIN, deficiency of kidney essence, soreness of the waist and knees, the diseases such as early whitening of beard and hair.
Herba Dendrobii in the present invention has the stomach reinforcing of promoting the production of body fluid, and effect of clearing away heat and nourishing YIN is applicable to control consumption of body fluid caused by febrile disease, xerostomia excessive thirst, and deficiency-heat after being ill, the moon is hindered order and is secretly waited disease.
Radix seu Caulis Verntilaginis Leiocarpae in the present invention mainly contains alkaloid, the compositions such as flavonoid glycoside, phenols, aminoacid, anthraquinone; Have benefiting vital QI and blood, effect of dispelling, collateral-activating, cures mainly deficiency of both QI and blood, rheumatalgia, traumatic injury.
Blood party in the present invention has wind-damp dispelling, promoting blood flow to regulate menstruation, effect of reducing swelling and alleviating pain.
Radix seu Caulis Embeliae Parviflorae in the present invention has enriches blood; The effect of invigorating blood circulation.
Owing to adopting technique scheme, the beneficial effect that the present invention obtains is:
The present invention is according to Traditional Chinese Medicine and strong medical knowledge opinion, by science compatibility, and through experiment for many years grope exploitation obtain; This Chinese medicine composition has nourishing blood to expel wind, effect of Runzao Zhiyang, and for blood-deficiency and wind-dry type psoriasis treatment, its determined curative effect, dosage form is stable, quality controllable and have no side effect, and is to be easy to the modern preparation extensively used.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, and protection scope of the present invention is not only confined to following examples.
Embodiment 1: the preparation of the psoriasic Chinese medicine composition mixture for the treatment of blood-deficiency and wind-dry type
Take respectively Radix Polygoni Multiflori 9g, Arillus Longan 9g, Caulis Spatholobi 12g, Fructus Mori 9g, Herba Schizonepetae 5g, Rhizoma Polygonati 9g, Herba Dendrobii 6g, Radix seu Caulis Verntilaginis Leiocarpae 15g, the 15g of blood party, Radix seu Caulis Embeliae Parviflorae 15g and sucrose 50g, for subsequent use; By the sucrose heating for dissolving taking in advance, boil, stop heating, filtered while hot, for subsequent use; By the above-mentioned Radix Polygoni Multiflori taking, Arillus Longan, Caulis Spatholobi, Stichopus japonicus, Fructus Mori, Herba Schizonepetae, Rhizoma Polygonati, Herba Dendrobii, Radix seu Caulis Verntilaginis Leiocarpae, blood party and Radix seu Caulis Embeliae Parviflorae, respectively through water extraction, filtration, and concentrated, obtain concentrated solution separately, for subsequent use; The sucrose syrup making is mixed with the concentrated solution making, and adds 0.3g sodium benzoate and 0.08g ethyl hydroxybenzoate, stir and make it whole dissolvings, add 15000mL water, stir evenly, and be heated to boiling.
Embodiment 2: the preparation of the psoriasic Chinese medicinal composition granules for the treatment of blood-deficiency and wind-dry type
Take respectively Radix Polygoni Multiflori 5g, Arillus Longan 7g, Caulis Spatholobi 17g, Fructus Mori 12g, Herba Schizonepetae 3g, Rhizoma Polygonati 5g, Herba Dendrobii 8g, Radix seu Caulis Verntilaginis Leiocarpae 12g, the 12g of blood party, Radix seu Caulis Embeliae Parviflorae 12g and sucrose 50g, for subsequent use; By the sucrose grinds taking in advance, for subsequent use; By the above-mentioned Radix Polygoni Multiflori taking, Arillus Longan, Caulis Spatholobi, Stichopus japonicus, Fructus Mori, Herba Schizonepetae, Rhizoma Polygonati, Herba Dendrobii, Radix seu Caulis Verntilaginis Leiocarpae, blood party and Radix seu Caulis Embeliae Parviflorae, respectively through water extraction, filtration, and concentrated, obtain concentrated solution separately, for subsequent use; The sucrose Icing Sugar making is mixed with the concentrated solution making, granulate, dry.
Embodiment 3: the preparation of the psoriasic Chinese medicinal composition capsules agent for the treatment of blood-deficiency and wind-dry type
Take respectively Radix Polygoni Multiflori 14g, Arillus Longan 12g, Caulis Spatholobi 13g, Fructus Mori 6g, Herba Schizonepetae 8g, Rhizoma Polygonati 13g, Herba Dendrobii 3g, Radix seu Caulis Verntilaginis Leiocarpae 20g, the 20g of blood party, Radix seu Caulis Embeliae Parviflorae 20g and starch 40g, for subsequent use; By the above-mentioned Radix Polygoni Multiflori taking, Arillus Longan, Caulis Spatholobi, Stichopus japonicus, Fructus Mori, Herba Schizonepetae, Rhizoma Polygonati, Herba Dendrobii, Radix seu Caulis Verntilaginis Leiocarpae, blood party and Radix seu Caulis Embeliae Parviflorae, respectively through water extraction, filtration, and concentrated, obtain concentrated solution separately, for subsequent use; The concentrated solution making is mixed homogeneously with starch, granulate, dry, be packed into capsule.
Clinical trial part
Clinical data statistics:
By 50 routine psoriatics' clinical research, observation the present invention treats the clinical efficacy of psoriasis resting stage (blood-deficiency and wind-dry type).Method: 50 routine homeliness type psoriatics' resting stage are divided into two groups at random, treatment group 25 examples, matched group 25 examples.Two groups of cases all have comparability at aspects such as age, sex, the course of disease and disease severities.Treatment group adopts the present invention for oral administration, and matched group adopts oral enlightening silver strip, two groups of outer vaseline that are coated with of while.The scoring of observing two groups for the treatment of front and back skin lesion changes, and carries out statistical procedures, result: 1. treatment group total effective rate is 82.22%.Matched group total effective rate is 57.78%; 2. after liang group internal therapy, total mark all has decline, and difference has two groups of significances (P<0.05) and compares P<0.05; The present invention total mark improve aspect with the comparison of enlightening silver strip, difference has significance (P<0.05), the present invention and enlightening silver strip all have good therapeutic effect to psoriasis resting stage (blood-deficiency and wind-dry type), wherein, the present invention can significantly reduce the symptoms such as psoriatic lesion area, erythema, infiltration, squama and pruritus, its curative effect is better than enlightening silver strip, and does not find obvious untoward reaction at treatment viewing duration, shows that safety of medicine of the present invention is effective.
Concrete case of illness introduce:
Song, man, 56 years old, patient suffered from the neural dermatitis several years of general property, accompanies violent pruritus, when anxious state of mind, increases the weight of.First visit: Head And Face, trunk, forearm be dispersed in distribute differ in size, patch in irregular shape, boundary is clear, cutaneous ridge increases, sulci of skin is deepened, pachyderma is coarse, shape is as Corii Bovis seu Bubali, xerosis cutis, a little desquamation, has scratch, blood crusts; Conscious paroxysmal pruritus, more so, increase the weight of when anxious state of mind night, companion's xerostomia happiness drink, constipation with dry stool.Once used Western medicine innerwear outer treatment DeGrain, easily recurrence.Examine it: red tongue, the few Tianjin of yellow and thin fur, the floating string of feeling the pulse.Examining it is: blood-deficiency and wind-dry psoriasis (generalized neurodermatitis), and after 3 courses for the treatment of of medicine that trial edition invention is made, transference cure, pruritus obviously alleviates, and skin lesion takes a turn for the better before, and xerostomia symptom alleviates, and it is normal that stool recovers.
Mr. Chen, 48 years old, is diagnosed as blood-deficiency and wind-dry psoriasis, symptom: skin pruritus and desquamation skin lesion are dry easily to be split, erythra color is light or dark, and squama is thick, and skin lesion substrate is softer, it is main that skin lesion is sentenced speckle shape, and the many places such as patient's scalp, elbow, knee joint all have, with pruritus.Patient is also with pharyngodynia with dryness, xerocheilia, susceptible to lose temper due to restlessness, and feelings will is gloomy, drowsiness uneasiness and insomnia and dreamful sleep.After 4 courses for the treatment of of medicine that trial edition invention is made, transference cure, pruritus alleviates, and skin lesion place speckle obviously reduces, and sleep quality improves.
Claims (5)
1. the psoriasic Chinese medicine composition for the treatment of blood-deficiency and wind-dry type, it is characterized in that comprising the raw material of following parts by weight: 5 parts～14 parts of Radix Polygoni Multiflori, 7 parts～12 parts of Arillus Longans, 13 parts～17 parts of Caulis Spatholobis, 6 parts～12 parts, Fructus Mori, 3 parts～8 parts of Herba Schizonepetae, 5 parts～13 parts of Rhizoma Polygonatis, 3 parts～8 parts of Herba Dendrobiis, 12 parts～20 parts of Radix seu Caulis Verntilaginis Leiocarpae, 12 parts～20 parts of 12 parts～20 parts of blood parties and Radix seu Caulis Embeliae Parviflorae.
2. according to the described psoriasic Chinese medicine composition for the treatment of blood-deficiency and wind-dry type of claim 1, the parts by weight that it is characterized in that raw material are: 9 parts of Radix Polygoni Multiflori, 9 parts of Arillus Longans, 12 parts of Caulis Spatholobis, 9 parts, Fructus Mori, 5 parts of Herba Schizonepetae, 9 parts of Rhizoma Polygonatis, 6 parts of Herba Dendrobiis, 15 parts of Radix seu Caulis Verntilaginis Leiocarpae, 15 parts of 15 parts of blood parties and Radix seu Caulis Embeliae Parviflorae.
3. according to the described psoriasic Chinese medicine composition for the treatment of blood-deficiency and wind-dry type of claim 1, the parts by weight that it is characterized in that raw material are: 5 parts of Radix Polygoni Multiflori, 7 parts of Arillus Longans, 17 parts of Caulis Spatholobis, 12 parts, Fructus Mori, 3 parts of Herba Schizonepetae, 5 parts of Rhizoma Polygonatis, 8 parts of Herba Dendrobiis, 12 parts of Radix seu Caulis Verntilaginis Leiocarpae, 12 parts of 12 parts of blood parties and Radix seu Caulis Embeliae Parviflorae.
4. according to the described psoriasic Chinese medicine composition for the treatment of blood-deficiency and wind-dry type of claim 1, the parts by weight that it is characterized in that raw material are: 14 parts of Radix Polygoni Multiflori, 12 parts of Arillus Longans, 13 parts of Caulis Spatholobis, 6 parts, Fructus Mori, 8 parts of Herba Schizonepetae, 13 parts of Rhizoma Polygonatis, 3 parts of Herba Dendrobiis, 20 parts of Radix seu Caulis Verntilaginis Leiocarpae, 20 parts of 20 parts of blood parties and Radix seu Caulis Embeliae Parviflorae.
5. according to the psoriasic Chinese medicine composition for the treatment of blood-deficiency and wind-dry type described in claim 1 or 2 or 3 or 4, it is characterized in that: this Chinese medicine composition is made mixture, granule or capsule.
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| CN201410346837.1A CN104147378B (en) | 2014-07-21 | 2014-07-21 | Treat the psoriasic Chinese medicine composition of blood-deficiency and wind-dry type |
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| CN201410346837.1A CN104147378B (en) | 2014-07-21 | 2014-07-21 | Treat the psoriasic Chinese medicine composition of blood-deficiency and wind-dry type |
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| CN104147378A true CN104147378A (en) | 2014-11-19 |
| CN104147378B CN104147378B (en) | 2018-06-12 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984132A (en) * | 2015-07-22 | 2015-10-21 | 袁玥 | Traditional Chinese medicine for treating psoriasis caused by dampness |
| EP4125983A4 (en) * | 2020-04-03 | 2024-02-14 | Medihelpline Co., Ltd. | An oral pharmaceutical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of inflammatory disease and the use thereof |
-
2014
- 2014-07-21 CN CN201410346837.1A patent/CN104147378B/en active Active
Non-Patent Citations (1)
| Title |
|---|
| 吴淞: "谈谈皮肤病的辨治", 《江苏中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984132A (en) * | 2015-07-22 | 2015-10-21 | 袁玥 | Traditional Chinese medicine for treating psoriasis caused by dampness |
| EP4125983A4 (en) * | 2020-04-03 | 2024-02-14 | Medihelpline Co., Ltd. | An oral pharmaceutical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of inflammatory disease and the use thereof |
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| Publication number | Publication date |
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| CN104147378B (en) | 2018-06-12 |
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Address after: 543002 28 Fumin road two, the Guangxi Zhuang Autonomous Region, Wuzhou Patentee after: GUANGXI WUZHOU SANHE PHARMACEUTICAL Co.,Ltd. Address before: 543002 28 Fumin road two, the Guangxi Zhuang Autonomous Region, Wuzhou Patentee before: GUANGXI WUZHOU SANHE PHARMACEUTICAL Co.,Ltd. |
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Denomination of invention: Traditional Chinese medicine composition for treating psoriasis of blood deficiency and wind dryness type Effective date of registration: 20220106 Granted publication date: 20180612 Pledgee: Bank of Guilin Co.,Ltd. Wuzhou branch Pledgor: GUANGXI WUZHOU SANHE PHARMACEUTICAL CO.,LTD. Registration number: Y2022450000002 |