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CN104126686A - Medicinal tea for treating coronary heart disease and angina pectoris and preparation method thereof - Google Patents

Medicinal tea for treating coronary heart disease and angina pectoris and preparation method thereof Download PDF

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Publication number
CN104126686A
CN104126686A CN201410359410.5A CN201410359410A CN104126686A CN 104126686 A CN104126686 A CN 104126686A CN 201410359410 A CN201410359410 A CN 201410359410A CN 104126686 A CN104126686 A CN 104126686A
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tea
green tea
minutes
concentrated
heart disease
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CN201410359410.5A
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Chinese (zh)
Inventor
孙迺居
张爱萍
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Heilongjiang Beiqishen Pharmaceutical Co Ltd
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Heilongjiang Beiqishen Pharmaceutical Co Ltd
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Priority to CN201410359410.5A priority Critical patent/CN104126686A/en
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Abstract

The invention aims to provide a medicinal tea for treating a coronary heart disease and angina pectoris. Radix salviae miltiorrhizae is used as a main medicine, a green tea is matched, and a scientific reasonable method is adopted to obtain the bagged medicinal tea. The radix salviae miltiorrhizae has the efficacies of promoting blood circulation, removing blood stasis, calming the nerves, tranquilizing mind, evacuating pus and relieving a pain, and the bitter cool green tea which can clear away the damp-heat from heads and eyes is added for assist, so that the medicinal tea is suitable for diseases, such as the coronary heart disease, the angina pectoris, arteriosclerosis and ischemic cerebral apoplexy.

Description

A kind of medicinal tea for the treatment of coronary disease and angina pectoris and preparation method thereof
One, technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of medicinal tea for the treatment of coronary disease and angina pectoris and preparation method thereof.
Two, background technology
Coronary artery congee sclerosis or follow spasm to cause myocardial anoxia and the heart disease that causes, it with the functional change of coronary artery (spasm) together with, general designation coronary atherosclerotic heart disease, abbreviation coronary heart disease, also claims ischemic heart disease.Angina pectoris means acute temporary myocardial ischemia, anoxic and the ictal pectoralgia that causes is main clinical syndrome, belongs to the traditional Chinese medical science " chest impediment and cardialgia " category.Traditional Chinese medicine is thought and is caused hypofunction of YANG QI in chest by toxin body-centered kidney qi YANG deficiency.Inernal injuries caused by seven emotions causes the stagnation of the circulation of vital energy.Eating and drinking without temperance, internal lesion caused by overexertion is excessive, and impairing the spleen and stomach is made raw phlegm turbid.Cold-evil attacks outward, causes the cold arteries and veins of being suspicious of.The cloudy heart arteries and veins of above-mentioned all kinds of disease and evil factor numbness and be chest impediment and cardialgia.Its interpretation of the cause, onset and process of an illness mainly take the heart suffer from a deficiency of the kidney weak for, take yang-energy void as main, the prolonged illness deficiency of yang affecting yin, deficiency in both YIN and YANG.With qi depression to blood stasis, cold doubting, phlegm is turbid is mark.The symptom of its diagnosis: (1) left side chest is born or the burst of Danzhong place is felt oppressed and pain, characteristic of pain is cusalgia, angina, shouting pain or secret anguish, unclean sense of discomfort etc., the back of the body, forearm, throat, gastral cavilty portion etc. can be altered and take on to pain often, very can thirty hand few cloudy, the meridian of Hand-JUE YIN of person follows row position and alters to middle finger or little finger of toe, the palpitaition of often holding concurrently.(2) sudden onset, time while doing only, outbreak repeatedly.Duration is of short duration, general several seconds to tens of minutes, after having a rest or taking medicine, can alleviate rapidly.(3) be more common in above middle agely, often, because of feelings will fluctuation, climate change, drinks gluttony more, overworks etc. and brings out.While also having or not obvious inducement or peace and quiet, send out patient.(4) electrocardiogram should be classified indispensable routine inspection as, can make if desired Holter, mapping electrocardiogram and cardiac determination, exercise ECG.The obvious myocardial ischemia of electrocardiogram during rest, ECG exercise test is positive, contributes to diagnosis.
It is interior through > > that " obstruction of qi in the chest " name of disease sees < < the earliest, all on the books to the performance of this sick cause of disease, general symptom and angina pectoris.Opinion > > when < < Plain Questions is hidden gas method: " heart patient, chest pain, discomfort and fullness in the hypochondrium, hypochondriac pain, bears pain between back of the body omoplate, pain in the medial sides of both arms." the < < Ling Shu Miraculous Pivot or Divine Axis disease > > that faints: " and angina pectoris, bluish colour of the limbs extending up to the elbows and knees, very pained, onset of disease in the morning and dying in the evening, onset of disease in the evening and dying in the next morning.Han dynasty Zhang Zhongjing is at < < Synopsis Golden Chamber, lose heart abnormal pulse card of chest impediment and cardialgia is controlled and in the chapters such as > >, has further been made a series of arteries and veins cards and describe, and proposes the square medicine of comparison system.As " pain over the chest and back, loses heart for the disease of the obstruction of qi in the chest, dyspnea and expectoration, pulse at CUN KOU being deep and slow, GUAN being pulse faint,tense and rapid, Gualou Xiebai Baijiu Tang ".The Chen Nian ancestral < < of Qing Dynasty time side song is drawn together all pains of Danshen blood-activating and qi-promoting treatment trusted subordinate for > >.The Wang Qingren < < of Qing Dynasty correction of the errors of medical works > > controls chest impediment and cardialgia etc. with xuefu zhuyu decoction activating blood circulation to dissipate blood stasis and dredge the collateral, and this disease is all had to good therapeutic effect.
In a word, in treatment, this has obtained good curative effect aspect sick to traditional Chinese medicine, but part prescription bring certain toxic and side effect more or less can to patient's stomach and intestine, liver kidney.And some drugs exists takes the defects such as inconvenience, onset is slow.
Three, summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide that a kind of formula is simple, taking convenience, the clothes that are easy to carry easily be for a long time to medicative medicinal tea of coronary disease and angina pectoris and preparation method thereof.This medicinal tea determined curative effect and having no side effect.
To achieve these goals, the present invention is by the following technical solutions:
The invention provides a kind of coronary heart disease and anginal medicinal tea for the treatment of, by following raw materials according medicine, be prepared from, be weight portion: 28~72 parts of the reds sage root, 12~28 parts of green tea.
The invention provides a kind of coronary heart disease and anginal medicinal tea for the treatment of, its preparation method comprises the following steps:
(1) prepare green tea meal: green tea, with after Co60 radiation sterilization, is ground into meal by green tea, standby;
(2) lixiviate is concentrated: get red sage root boiling secondary, 120 minutes for the first time, 90 minutes for the second time, collecting decoction, filtered filtrate and be concentrated into the liquid that relative density is 1.10~1.15 (80 ℃), lets cool;
(3) ethanol reclaims: under agitation slowly add ethanol to make to reach 60% containing alcohol amount, fully stir, standing 24 hours, filter filtrate recycling ethanol to be concentrated into relative density be 1.35~1.40 (50~60 ℃);
(4) mix: thick tea, clear cream are placed in to mixer and mix, mixing time 20 minutes;
(5) dry: by the material uniform spreading mixing, in dish, between thickness 1.5~2cm, when temperature rises to 60~80 ℃ of scopes, timing starts, dry 10h;
(6) whole grain: by dried compound, put in Fastgranulatemachine revolution: 940~1440 revs/min, charging rate 1.5kg/ divides, the whole 1.5 hours time of grain;
(7) always mixed: the oven dry material after whole grain to be inverted in action of forced stirring mixer, to be mixed 12 revs/min of 30 minutes, revolution;
(8) packing: after mixing, sterile packaged, obtains.
The pharmacology of the present invention's main Chinese medicine material used is as follows:
The red sage root: nature and flavor are bitter, cold nature.Can be promoting blood circulation and removing blood stasis, cool blood, calms the nerves.Enter the heart, spleen ear two warps.According to the < < book on Chinese herbal medicine > > that looks for the truth: the red sage root has the effect into the broken stasis of blood of percardium.Modern medicine study confirms, its energy coronary artery dilator, and increase coronary flow, improves myocardial ischemia, infraction and cardiac function, regulates the rhythm of the heart, and can expand peripheral vascular, improves microcirculation; Can improve the body oxygen of resistance to blood ability; There is anticoagulation, promote fibrinolytic, suppress platelet aggregation, suppress thrombotic effect; Can reduce blood fat, suppress coronary atherosclerosis and form; Can shorten the convalescence of red blood cell and hemochrome, Reticulocyte is increased, can promote the reparation of tissue, accelerate the healing of fracture; Nervous centralis is had to inhibitory action; There is antitumor action; Energy enhanced machine body immunity function; Can reduce blood sugar; The various bacteria such as tubercle bacillus are had to inhibitory action.
Green tea: taste slightly bitterness is cold, there is the heat that disappears, relieve summer heat, detoxify, reduce internal heat, fall dry, quench the thirst, promote the production of body fluid, function that cardiac stimulant is refreshed oneself.The green soup of green tea greenery, clear fresh tasty and refreshing, the sweet perfume (or spice) of flavour slightly bitter cold taste, be rich in the nutritional labelings such as vitamin, amino acid, mineral matter, and tool increases the effect of nutrition again.Tea Polyphenols has very strong non-oxidizability and physiologically active, can promote body fat metabolism important role; Can block the multiple carcinogen in vivo such as ammonium nilrite synthetic, and there is the effect of direct killing cancer cell and raising human body immunocompetence; Also have stronger astriction, pathogen, virus are had to obvious inhibition and killing action.Caffeine in green tea can impel human central nervous excited, strengthens corticocerebral excited process, plays the effect that the benefit of refreshing oneself is thought, cleared away heart-fire; Can also stimulate kidney, impel urine to excrete rapidly, improve the rate that leaches of kidney.This is can improve the secretory volume of gastric juice due to the caffeine in tealeaves, can help digest, and strengthens lipolytic ability.
Four, description of drawings 1 is process chart of the present invention.Wherein for material, process, process; → represent operation, material, personnel's trend and be connected; Zero represents material.
Five, specific embodiments
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but the present invention is not limited to the following stated.
One, Study on Preparation:
Embodiment 1 the invention provides a kind of coronary heart disease and anginal medicinal tea for the treatment of, and by following raw materials according medicine, is prepared from, and is weight portion: 60 parts of the reds sage root, 25 parts of green tea.
The invention provides a kind of coronary heart disease and anginal medicinal tea for the treatment of, its preparation method comprises the following steps:
(1) prepare green tea meal: green tea, with after Co60 radiation sterilization, is ground into meal by green tea, standby;
(2) lixiviate is concentrated: get red sage root boiling secondary, 120 minutes for the first time, 90 minutes for the second time, collecting decoction, filtered filtrate and be concentrated into the liquid that relative density is 1.10~1.15 (80 ℃), lets cool;
(3) ethanol reclaims: under agitation slowly add ethanol to make to reach 60% containing alcohol amount, fully stir, standing 24 hours, filter filtrate recycling ethanol to be concentrated into relative density be 1.35~1.40 (50~60 ℃);
(4) mix: thick tea, clear cream are placed in to mixer and mix, mixing time 20 minutes;
(5) dry: by the material uniform spreading mixing, in dish, between thickness 1.5~2cm, when temperature rises to 60~80 ℃ of scopes, timing starts, dry 10h;
(6) whole grain: by dried compound, put in Fastgranulatemachine revolution: 940~1440 revs/min, charging rate 1.5kg/ divides, the whole 1.5 hours time of grain;
(7) always mixed: the oven dry material after whole grain to be inverted in action of forced stirring mixer, to be mixed 12 revs/min of 30 minutes, revolution;
(8) packing: after mixing, sterile packaged, obtains.
The instructions of taking of medicinal tea of the present invention: boiling water is taken after being infused in hot water or decoction, 3 times on the one, each 1 bag.All cases 1 month is a course for the treatment of, heavier to the state of an illness, and the course of disease can extend continuous with two courses for the treatment of compared with elder.Period in a medicine stop using other similar treatment coronary heart disease and angina drugs.
Model case: patient's first, age: 52 years old; Sex: the male sex; One day, occur compared with more violent and frequently angina pectoris in the past, the angina pectoris duration is longer, and inducement is not obvious, takes monobel, but curative effect is poor, during angina pectoris attacks with feeling sick, vomiting, profuse sweating, bradycardia, acute cardiac insufficiency, severe arrhythmia.
Take and originally execute a kind of medicinal tea for the treatment of coronary disease and angina pectoris of routine gained, boiling water is taken after being infused in hot water or decoction, and 3 times on the one, each 1 bag.Take 20 days, angina pectoris obviously alleviates, and nauseating, symptoms of emesis disappears, and precordialgia obviously alleviates, and fatigue and weak also alleviates, and takes one month, and the blood supply of electrocardiogram coronary artery obviously improves, then continues to take one month, the recovery from illness of patient's self-induction.
Embodiment 2 one the invention provides a kind of coronary heart disease and anginal medicinal tea for the treatment of, and by following raw materials according medicine, is prepared from, and is weight portion: 46 parts of the reds sage root, 20 parts of green tea.
The invention provides a kind of coronary heart disease and anginal medicinal tea for the treatment of, its preparation method comprises the following steps:
(1) prepare green tea meal: green tea, with after Co60 radiation sterilization, is ground into meal by green tea, standby;
(2) lixiviate is concentrated: get red sage root boiling secondary, 120 minutes for the first time, 90 minutes for the second time, collecting decoction, filtered filtrate and be concentrated into the liquid that relative density is 1.10~1.15 (80 ℃), lets cool;
(3) ethanol reclaims: under agitation slowly add ethanol to make to reach 60% containing alcohol amount, fully stir, standing 24 hours, filter filtrate recycling ethanol to be concentrated into relative density be 1.35~1.40 (50~60 ℃);
(4) mix: thick tea, clear cream are placed in to mixer and mix, mixing time 20 minutes;
(5) dry: by the material uniform spreading mixing, in dish, between thickness 1.5~2cm, when temperature rises to 60~80 ℃ of scopes, timing starts, dry 10h;
(6) whole grain: by dried compound, put in Fastgranulatemachine revolution: 940~1440 revs/min, charging rate 1.5kg/ divides, the whole 1.5 hours time of grain;
(7) always mixed: the oven dry material after whole grain to be inverted in action of forced stirring mixer, to be mixed 12 revs/min of 30 minutes, revolution;
(8) packing: after mixing, sterile packaged, obtains.
The instructions of taking of medicinal tea of the present invention: boiling water is taken after being infused in hot water or decoction, 3 times on the one, each 1 bag.All cases 1 month is a course for the treatment of, heavier to the state of an illness, and the course of disease can extend continuous with two courses for the treatment of compared with elder.Period in a medicine stop using other similar treatment coronary heart disease and angina drugs.
Model case: patient's second, age: 47 years old; Sex: women; Main suit: intermittent pectoralgia 4 months; Present illness history: patient without obvious inducement pectoralgia, for vexed pain after breastbone, was continuation before 5 hours, the radiation of companion's back part, without abdominal distension, without stomachache, without n and V, generates heat without chilly, without cough and expectoration.Discuss: the blood supply of electrocardio diagram coronary artery is obviously not enough, through checking the basic pectoralgia that other reasons causes of getting rid of, pectoralgia diagnosis is clear and definite due to coronary heart disease.
Take a kind of medicinal tea for the treatment of coronary disease and angina pectoris of the present embodiment gained, boiling water is taken after being infused in hot water or decoction, and 3 times on the one, each 1 bag.Take 20 days, pectoralgia obviously alleviates, and confusingly in the heart also alleviates, and takes one month (course for the treatment of), and symptom is eliminated, and sleep, without vexed, then continues to take 1 month, does not occur any discomfort when patient takes, and patient's self-induction is fully recovered.
Two, effect test research
A kind of medicinal tea for the treatment of coronary disease and angina pectoris of development.Entrust the attached Second Academy of Heilongjiang University of Chinese Medicine, in October, 2005-December, this medicinal tea treatment coronary heart disease and curative effect to treat angina pectoris are observed.
Standard compliant coronary heart disease and anginal inpatient select in coronary heart disease section, and small part is that treat-and-release patient amounts to 180 examples, is divided at random treatment group 130 examples, control group 50 examples, the male sex's 82 examples in treatment group, women's 48 examples, 48 years old mean age; The male sex's 31 examples in control group, women's 19 examples, mean aves 46 example, there was no significant difference between two groups of its course of disease, the state of an illness etc., has comparativity.
Tcm diagnosis standard: suffocating pain over the chest, very chest pain radiating to the back; The lighter dislikes chest distress, unsmooth breath; Electrocardioscopy has ischemic change or the exercise test positive.
Chinese medical discrimination heart blood silt: stabbing pain over the chest, angina, fixingly do not move, enter Night Watch very, time or palpitation and uneasiness, purplish tongue, deep wiry pulse.
Include case standard in: have obstruction of qi in the chest primary symptom, diagnosis is clear and definite, meets Chinese medical discrimination, and the coronary heart disease and the patient with angina pectoris that show effect weekly more than twice, can include test case in.
Table 1 is taken embodiment, curative effect comparison between two groups.
The demonstration of table 1 result, this product treatment coronary heart disease and angina pectoris and control group are relatively without significant difference (P > 0.05), but total effective rate is 92.31%.
Table 2 is taken the clinical cardinal symptoms in two groups of medicine front and back and is improved relatively.
The demonstration of table 2 result, this product compares without explicitly difference (P > 0.05) with control group coronary disease and angina pectoris symptom is evident in efficacy, but total effective rate is 91.16%.
Table 3 this product treatment coronary heart disease and angina pectoris physical index curative effect.
The demonstration of table 3 result, this product treatment coronary heart disease and angina pectoris and control group are relatively without significant difference (P > 0.05), but its total effective rate is 92.31%.
The present invention be by thering is stasis-dispelling and pain-killing, the red sage root promoting blood circulation and removing obstruction in channels, the relieving restlessness that clears away heart-fire is primary raw material, be aided with the refining bag tea agent forming of green tea, according to clinical trial design plan, this product treatment coronary heart disease and angina pectoris are carried out to 130 routine clinical observations, it is evident in efficacy, and total effective rate is 92.31% and taking convenience, and patient accepts, take in process there are no toxic and side effect, be worth of widely use.
It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or obtain undoubtedly according to the written description of file, all should think the claimed scope of this patent.

Claims (3)

1. a medicinal tea for the treatment of coronary disease and angina pectoris.It is characterized in that, by weight, by following component raw material proportioning, formed: 28~72 parts of the reds sage root, 12~28 parts of green tea.
(1) prepare green tea meal: green tea, with after Co60 radiation sterilization, is ground into meal by green tea, standby;
(2) lixiviate is concentrated: get red sage root boiling secondary, 120 minutes for the first time, 90 minutes for the second time, collecting decoction, filtered filtrate and be concentrated into the liquid that relative density is 1.10~1.15 (80 ℃), lets cool;
(3) ethanol reclaims: under agitation slowly add ethanol to make to reach 60% containing alcohol amount, fully stir, standing 24 hours, filter filtrate recycling ethanol to be concentrated into relative density be 1.35~1.40 (50~60 ℃);
(4) mix: the thick tea of green tea, clear cream are placed in to mixer and mix, mixing time 20 minutes;
(5) dry: by the material uniform spreading mixing, in dish, between thickness 1.5~2cm, when temperature rises to 60~80 ℃ of scopes, timing starts, dry 10h;
(6) whole grain: by dried compound, put in Fastgranulatemachine revolution: 940-1440 rev/min, charging rate 1.5kg/ divides, the whole 1.5 hours time of grain;
(7) always mixed: the oven dry material after whole grain to be inverted in action of forced stirring mixer, to be mixed 12 revs/min of 30 minutes, revolution;
(8) packing: after mixing, sterile packaged, obtains.
2. a kind of coronary heart disease and anginal medicinal tea for the treatment of as claimed in claim 1, its preparation method is as follows:
By weight, by following component raw material proportioning, formed: 28~72 parts of the reds sage root, 12~28 parts of green tea.
(1) prepare green tea meal: green tea, with after Co60 radiation sterilization, is ground into meal by green tea, standby;
(2) lixiviate is concentrated: get red sage root boiling secondary, 120 minutes for the first time, 90 minutes for the second time, collecting decoction, filtered filtrate and be concentrated into the liquid that relative density is 1.10~1.15 (80 ℃), lets cool;
(3) ethanol reclaims: under agitation slowly add ethanol to make to reach 60% containing alcohol amount, fully stir, standing 24 hours, filter filtrate recycling ethanol to be concentrated into relative density be 1.35~1.40 (50~60 ℃);
(4) mix: the thick tea of green tea, clear cream are placed in to mixer and mix, mixing time 20 minutes;
(5) dry: by the material uniform spreading mixing, in dish, between thickness 1.5~2cm, when temperature rises to 60~80 ℃ of scopes, timing starts, dry 10h;
(6) whole grain: by dried compound, put in Fastgranulatemachine revolution: 940-1440 rev/min, charging rate 1.5kg/ divides, the whole 1.5 hours time of grain;
(7) always mixed: the oven dry material after whole grain to be inverted in action of forced stirring mixer, to be mixed 12 revs/min of 30 minutes, revolution;
(8) packing: after mixed platform, sterile packaged, obtains.
3. a kind of coronary heart disease and anginal medicinal tea for the treatment of as claimed in claim 1, its formulation is medicinal tea.
CN201410359410.5A 2014-07-25 2014-07-25 Medicinal tea for treating coronary heart disease and angina pectoris and preparation method thereof Pending CN104126686A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104115955A (en) * 2014-08-01 2014-10-29 潘彬 Salvia miltiorrhiza tea capable of protecting heart as well as preparation method and application of tea
CN106538744A (en) * 2016-12-21 2017-03-29 神农架林区中医医院 Red sage root nourishing heart tea in bag and preparation method thereof

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CN102669348A (en) * 2012-05-20 2012-09-19 北京绿源求证科技发展有限责任公司 Nutrition food of heart nourishing tea granule for nourishing heart
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CN102669348A (en) * 2012-05-20 2012-09-19 北京绿源求证科技发展有限责任公司 Nutrition food of heart nourishing tea granule for nourishing heart
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104115955A (en) * 2014-08-01 2014-10-29 潘彬 Salvia miltiorrhiza tea capable of protecting heart as well as preparation method and application of tea
CN106538744A (en) * 2016-12-21 2017-03-29 神农架林区中医医院 Red sage root nourishing heart tea in bag and preparation method thereof

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