CN104096139A - Chinese medicinal preparation for treating metal mercury poisoning - Google Patents

Abstract

The invention relates to a Chinese medicinal preparation for treating metal mercury poisoning. The raw materials include: 50 parts of Smilax glabra, 15 parts of honeysuckle, 12 parts of Plantain Seed, 12 parts of rhizoma alismatis, 10 parts of cortex dictamni, 10 parts of rheum officinale, 12 parts of Radix Sophorae Flavescentis, 12 parts of tree peony bark, 10 parts of morinda officinalis, 10 parts of Malva verticillata L., and 10 parts of licorice. The preparation method of the ointment includes: weighing the raw materials 50 parts of Smilax glabra, 15 parts of honeysuckle, 12 parts of Plantain Seed, 12 parts of rhizoma alismatis, 10 parts of cortex dictamni, 10 parts of rheum officinale, 12 parts of Radix Sophorae Flavescentis, 12 parts of tree peony bark, 10 parts of morinda officinalis, 10 parts of Malva verticillata L., and 10 parts of licorice, preparing the materials into decoction pieces respectively, conducting autoclave steaming sterilization for 30-60min, and performing drying to obtain a sterile raw material, and making the sterile raw material into the Chinese medicinal preparation. With the efficacy of clearing heat and cooling blood, clearing toxin and promoting uresis, cleaning wound surfaces, and removing toxic pathogen, the Chinese medicinal preparation is used for treatment of metal mercury poisoning.

Description

The poisoning Chinese medicine preparation for the treatment of mercury metal

Technical field

The present invention relates to field of traditional Chinese; Be specifically related to a kind of poisoning Chinese medicine preparation of mercury metal for the treatment of.

Background technology

Mercury metal mainly with steam form in respiratory tract enters body, be difficult for absorbing by digestive tract; Mercury bichloride dissolubility is large, can through digestive tract, absorb rapidly.The hydrargyrum entering in body can be distributed in liver, kidney, brain, hair etc. with blood.In body, hydrargyrum is mainly by urine, defecate, and a small amount of hydrargyrum is discharged with saliva, perspiration and milk, and woman worker should not contact hydrargyrum in age of sucking and trimester of pregnancy, in order to avoid affect follow-on health.The symptom of mercurialism: suck high concentration mercury vapour in the short time, as gold-plating operation, manufacture high temperature instrument.Can cause acute mercurialism.But rare at present.Long Term Contact mercury vapour, can produce chronic mercury poisoning.Can have giddy, headache, insomnia, hypomnesis in early days, weakly wait neurasthenia symptom and spirit to change as timid, shy, irritability etc., in addition, sialorrhea, stomatitis and gingivitis are also the Early manifestations of chronic mercury poisoning.Muscular tremor is the characteristic symptom of mercurialism, shows as that finger, eyelid and tongue are trickle to tremble the initial stage, when serious, can develop into upper and lower extremities.The other medicines for the treatment of this disease in prior art exist therapeutic effect not obvious, the technological deficiency that side effect is large.

Summary of the invention

The object of the present invention is to provide a kind ofly to there is clearing away heat and cooling blood, the diuresis of detoxifying, cleanse the Chinese medicine preparation of wound surface, the malicious evil effect of clear profit, be used for the treatment of mercury metal poisoning.

Technical scheme of the present invention: the raw material of Chinese medicine preparation of the present invention and each component consumption thereof are groped in a large number to sum up through inventor and drawn, each component amount all has good effect within the scope of this: 50 parts of Rhizoma Smilacis Glabraes, 15 parts of Flos Loniceraes, 12 parts of Semen Plantaginiss, 12 parts of Rhizoma Alismatis, 10 parts of Cortex Dictamnis, 10 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Sophorae Flavescentiss, 12 parts of Cortex Moutans, 10 parts of Radix Morindae Officinaliss, 10 parts of Semen Abutilis, 10 parts, Radix Glycyrrhizae.

For reaching clearing away heat and cooling blood, the diuresis of detoxifying, cleanse wound surface, the malicious evil effect of clear profit, the present invention selects 10 parts of 50 parts of Rhizoma Smilacis Glabraes, 15 parts of Flos Loniceraes, 12 parts of Semen Plantaginiss, 12 parts of Rhizoma Alismatis, 10 parts of Cortex Dictamnis, 10 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Sophorae Flavescentiss, 12 parts of Cortex Moutans, 10 parts of Radix Morindae Officinaliss, 10 parts of Semen Abutilis, Radix Glycyrrhizae to combine, by these drug regimens, make each efficacy of drugs produce synergism, thereby it is poisoning effectively to treat mercury metal.In the raw materials of traditional Chinese medicinal materials of choosing, its effect and pharmacological action respectively:

Rhizoma Smilacis Glabrae: [function] removing toxic substances, dehumidifying, sharp joint.Cure mainly: control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, treats furuncle, carbuncle, scrofula, the limbs contracture due to syphilis and mercurialism, bones and muscles pain.

Flos Lonicerae: [meridian distribution of property and flavor] sweet in the mouth; Cold.Return lung; Stomach warp.[effect] heat-clearing and toxic substances removing.Epidemic febrile disease heating; Toxic-heat and blood stasis; Carbuncle furuncle; Sore throat and multi-infection disease.

Semen Plantaginis: nature and flavor: sweet; Light; Cold nature.Gui Jing: return lung meridian; Liver Channel; Kidney channel; Urinary bladder channel.Function: clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly: main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily.

Rhizoma Alismatis: Chinese crude drug.Theory of Chinese medical science thinks that it is cold in nature, has the effect of promoting diuresis to eliminate damp pathogen.Modern medicine study, Rhizoma Alismatis can reduce serum total cholesterol and triacylglycerol content, slows down atherogenesis; Rhizoma Alismatis and preparation modern times thereof are also used for the treatment of auditory vertigo, dyslipidemia, seminal emission, fatty liver and diabetes etc.But Rhizoma Alismatis has liver toxicity, nephrotoxicity, it is improper to take, and can allow liver, kidney occur swelling and other poisoning symptoms.Rhizoma Alismatis: be longer than promoting diuresis to eliminate damp pathogen, expel the heat-evil, for dysuria, edema distension, the puckery pain of stranguria with turbid discharge, seminal emission, foot knee joint flaccidity is soft; Fry Rhizoma Alismatis, be partial to and spleen eliminating dampness by diuresis, for phlegm retention, dysentery, the vertigo.

Cortex Dictamni: be the root bark of Rutaceae herbaceos perennial shaggy-fruited dittany and Dictamnus angustifolius.Spring, Qiu Erji excavate root, remove silt and rough bark, strip root bark, and section is dry.Life nature and flavor: hardship; Salty; Cold.Gui Jing: spleen channel; Lung meridian; Small intestine meridian; Stomach warp; Urinary bladder channel.Function: heat clearing and damp drying; Dispelling wind for relieving itching; Removing toxic substances.Cure mainly: the rubella due to wind heat noxious dampness; Eczema; Scabies; Jaundice; Damp-heat arthralgia.

Radix Et Rhizoma Rhei: the dry root and rhizome of polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex Balf. or Rheum officinale Rheum officinale Baill..Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria.Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.

Radix Sophorae Flavescentis (formal name used at school: plant Radix Sophorae flavescentis) belonging to for pulse family Radix Sophorae Flavescentis.Another name: matrine, Chinese scholartree, water Chinese scholartree, Tu Chinese scholartree, proud Chinese scholartree, wild Chinese scholartree or white stem.Sophora flavescens ait is the root of the perennial semishrub plant's Radix Sophorae Flavescentis of falling leaves.All producing all over China.Annual spring and autumn is gathered into medicinal.[nature and flavor] bitter in the mouth; Cold in nature.[return through] liver; Kidney; Large intestine; Small intestine meridian; Bladder; Heart channel; Urinary bladder channel.Function cures mainly: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.Radix Sophorae Flavescentis has the effect of anti-inflammation, and Propiobacterium, staphylococcus aureus, escherichia coli are all had to inhibitory action, can diuresis, antiallergic, ease pain, relieving asthma, eliminate the phlegm.

Cortex Moutan: Chinese medicine name.For the dry root bark of ranunculaceae peony.Originate in the ground such as Anhui, Shandong.Excavate root autumn, remove radicula, strip root bark, dry.Raw using or stir-fry use.< < Compendium of Materia Medica > >: " nourishing YIN to lower pathogenic fire is separated speckle poison, throat, diuresis stasis.Descendant specially controls fire mutually with yellow tiller, does not know that the merit of Cortex Moutan more wins also.Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it." modern study, contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action; The methanolic extract of Cortex Moutan has inhibition Platelet; Paeonol has the effects such as the central inhibitory actions such as calmness, cooling, antipyretic, analgesia, spasmolytic and atherosclerosis, diuresis, antiulcer.

Radix Morindae Officinalis: be the dry root of dicotyledon Rubiaceae (Rubiaceae) Radix Morindae Officinalis (Morinda officinalis How.).Cure mainly that impotence and seminal emission, cold womb are infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity be soft.

Semen Abutili has another name called certain herbaceous plants with big flowers, certain herbaceous plants with big flowers colza.Mature seed for Malvaceae annual herb plant Semen Abutili.The sweet cold sliding profit of this product, can relieving stranguria by diuresis, again can stimulating milk secretion, intestine moistening, and difficulty in urination and defecation person is all suitable.The effect with clearing away heat-damp and promoting diuresis, detumescence.Cure mainly urinary obstruction, urinary tract infection, urinary system calculus, lack of lactation after delivery etc.

Radix Glycyrrhizae: be a kind of tonification Chinese herbal medicine.Medicinal part is root and rhizome, and Radix Glycyrrhizae is grown in arid, semiarid sandy soil, desert edge and loess hill area more, is also easy to breeding drawing in the field in yellow irrigated area and flood land, and property is flat, sweet in the mouth.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong, in the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving cough and moistening lung, emergency removing toxic substances, mediation hundred medicines.

Chinese medicine for outer use of the present invention has clearing away heat and cooling blood, the diuresis of detoxifying, cleanse wound surface, the malicious evil effect of clear profit, is used for the treatment of mercury metal poisoning.So far, still do not find report and the application of relevant Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the Chinese medicine preparation that has better curative effect, thereby has completed the present invention.

Specific implementation method

Treatment mercury metal of the present invention is poisoning, and its raw material is: 50 parts of Rhizoma Smilacis Glabraes, 15 parts of Flos Loniceraes, 12 parts of Semen Plantaginiss, 12 parts of Rhizoma Alismatis, 10 parts of Cortex Dictamnis, 10 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Sophorae Flavescentiss, 12 parts of Cortex Moutans, 10 parts of Radix Morindae Officinaliss, 10 parts of Semen Abutilis, 10 parts, Radix Glycyrrhizae.

Its preparation method is following method: take 10 parts of 50 parts of raw material Rhizoma Smilacis Glabraes, 15 parts of Flos Loniceraes, 12 parts of Semen Plantaginiss, 12 parts of Rhizoma Alismatis, 10 parts of Cortex Dictamnis, 10 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Sophorae Flavescentiss, 12 parts of Cortex Moutans, 10 parts of Radix Morindae Officinaliss, 10 parts of Semen Abutilis, Radix Glycyrrhizae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.

Claims (2)

1. treat the poisoning Chinese medicine preparation of mercury metal, it is characterized in that: its raw material is; 50 parts of Rhizoma Smilacis Glabraes, 15 parts of Flos Loniceraes, 12 parts of Semen Plantaginiss, 12 parts of Rhizoma Alismatis, 10 parts of Cortex Dictamnis, 10 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Sophorae Flavescentiss, 12 parts of Cortex Moutans, 10 parts of Radix Morindae Officinaliss, 10 parts of Semen Abutilis, 10 parts, Radix Glycyrrhizae.

2. according to the poisoning Chinese medicine preparation for the treatment of mercury metal claimed in claim 1, it is characterized in that: its preparation method is following method: take 10 parts of 50 parts of raw material Rhizoma Smilacis Glabraes, 15 parts of Flos Loniceraes, 12 parts of Semen Plantaginiss, 12 parts of Rhizoma Alismatis, 10 parts of Cortex Dictamnis, 10 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Sophorae Flavescentiss, 12 parts of Cortex Moutans, 10 parts of Radix Morindae Officinaliss, 10 parts of Semen Abutilis, Radix Glycyrrhizae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.