CL2018000597A1 - Métodos para tratar enfermedades inflamatorias - Google Patents
Métodos para tratar enfermedades inflamatoriasInfo
- Publication number
- CL2018000597A1 CL2018000597A1 CL2018000597A CL2018000597A CL2018000597A1 CL 2018000597 A1 CL2018000597 A1 CL 2018000597A1 CL 2018000597 A CL2018000597 A CL 2018000597A CL 2018000597 A CL2018000597 A CL 2018000597A CL 2018000597 A1 CL2018000597 A1 CL 2018000597A1
- Authority
- CL
- Chile
- Prior art keywords
- methods
- inflammatory diseases
- treat inflammatory
- diseases
- treat
- Prior art date
Links
- 208000027866 inflammatory disease Diseases 0.000 title abstract 2
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
<p>Esta invención se refiere generalmente a métodos para el tratamiento de enfermedades relacionadas con IL-23, en particular, enfermedades inflamatorias, tales como la enfermedad de Crohn, que utilizan anticuerpos anti-IL-23A.</p>
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562220410P | 2015-09-18 | 2015-09-18 | |
US201562235654P | 2015-10-01 | 2015-10-01 | |
US201662295643P | 2016-02-16 | 2016-02-16 | |
US201662328863P | 2016-04-28 | 2016-04-28 | |
US201662335242P | 2016-05-12 | 2016-05-12 | |
US201662339192P | 2016-05-20 | 2016-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2018000597A1 true CL2018000597A1 (es) | 2018-07-27 |
Family
ID=57003593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2018000597A CL2018000597A1 (es) | 2015-09-18 | 2018-03-07 | Métodos para tratar enfermedades inflamatorias |
Country Status (16)
Country | Link |
---|---|
US (1) | US20170081402A1 (es) |
EP (1) | EP3350221A1 (es) |
JP (6) | JP6668461B2 (es) |
KR (1) | KR20180053395A (es) |
CN (1) | CN108026168A (es) |
AU (2) | AU2016323152A1 (es) |
BR (1) | BR112018003526A2 (es) |
CA (1) | CA2996645A1 (es) |
CL (1) | CL2018000597A1 (es) |
EA (1) | EA201890747A1 (es) |
HK (1) | HK1252037A1 (es) |
IL (2) | IL302197A (es) |
MX (3) | MX2018003174A (es) |
PH (1) | PH12018500578A1 (es) |
TW (2) | TWI733695B (es) |
WO (1) | WO2017048901A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE030916T2 (en) | 2010-11-04 | 2017-06-28 | Boehringer Ingelheim Int | Anti-IL-23 antibodies |
KR102124758B1 (ko) | 2012-05-03 | 2020-06-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 항-il-23p19 항체 |
JP2017524359A (ja) | 2014-07-24 | 2017-08-31 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Il−23a関連疾患の処置に有用なバイオマーカー |
TWI733695B (zh) * | 2015-09-18 | 2021-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 治療發炎性疾病之方法 |
EP3677597A1 (en) * | 2016-10-14 | 2020-07-08 | Boehringer Ingelheim International GmbH | Methods of treating diseases |
MX2020009265A (es) * | 2018-03-05 | 2020-10-01 | Janssen Biotech Inc | Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23. |
TWI850365B (zh) | 2019-04-22 | 2024-08-01 | 美商美國禮來大藥廠 | 治療克隆氏症(crohn's disease)的方法 |
CA3138241A1 (en) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
CN112578123B (zh) * | 2019-09-27 | 2022-10-25 | 成都中医药大学 | 检测粪钙卫蛋白含量的试剂在制备子宫病变筛查试剂盒中的用途 |
WO2022150472A1 (en) | 2021-01-06 | 2022-07-14 | Abbvie Inc. | Methods of treating crohn's disease and ulcerative colitis |
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US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
US4965199A (en) | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
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GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
WO1990003430A1 (en) | 1988-09-23 | 1990-04-05 | Cetus Corporation | Cell culture medium for enhanced cell growth, culture longevity and product expression |
FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
EP0940468A1 (en) | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
RU2139731C1 (ru) | 1992-11-13 | 1999-10-20 | Айдек Фармасьютикалс Корпорейшн (US | Способ лечения, антитела, гибридома |
US6037454A (en) | 1996-11-27 | 2000-03-14 | Genentech, Inc. | Humanized anti-CD11a antibodies |
US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
EP2452694B1 (en) | 2005-06-30 | 2018-11-14 | Janssen Biotech, Inc. | Anti-IL-23 antibodies, compositions, methods and uses |
DK1937721T3 (da) * | 2005-08-25 | 2010-10-18 | Lilly Co Eli | Anti-IL-23 antistoffer |
PT1931710T (pt) | 2005-08-31 | 2017-03-28 | Merck Sharp & Dohme | Anticorpos anti-il-23 manipulados |
JP5193881B2 (ja) | 2005-12-29 | 2013-05-08 | セントカー・インコーポレーテツド | ヒト抗il−23抗体、組成物、方法および用途 |
CN101600456A (zh) * | 2006-12-11 | 2009-12-09 | 惠氏公司 | 治疗il-13相关疾病和监测il-13相关疾病治疗的方法和组合物 |
AR065420A1 (es) | 2007-02-23 | 2009-06-03 | Schering Corp | Anticuerpos anti-il-23 p19 de ingenieria |
US20100111966A1 (en) * | 2007-02-23 | 2010-05-06 | Schering Corporation | Engineered anti-il-23p19 antibodies |
JO3244B1 (ar) * | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
HUE030916T2 (en) * | 2010-11-04 | 2017-06-28 | Boehringer Ingelheim Int | Anti-IL-23 antibodies |
KR102124758B1 (ko) * | 2012-05-03 | 2020-06-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 항-il-23p19 항체 |
CA2906384A1 (en) * | 2013-03-15 | 2014-09-18 | Amgen Inc. | Methods for treating crohn's disease using an anti-il23 antibody |
TWI733695B (zh) | 2015-09-18 | 2021-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 治療發炎性疾病之方法 |
JP7060806B2 (ja) * | 2018-08-22 | 2022-04-27 | 富士通株式会社 | 情報処理装置、データ管理方法およびデータ管理プログラム |
JP2020030579A (ja) * | 2018-08-22 | 2020-02-27 | 信越ポリマー株式会社 | Rfidタグ埋設体およびその製造方法 |
-
2016
- 2016-09-14 TW TW105129972A patent/TWI733695B/zh active
- 2016-09-14 TW TW110123878A patent/TWI811716B/zh active
- 2016-09-15 JP JP2018513853A patent/JP6668461B2/ja active Active
- 2016-09-15 CA CA2996645A patent/CA2996645A1/en active Pending
- 2016-09-15 BR BR112018003526A patent/BR112018003526A2/pt active Search and Examination
- 2016-09-15 US US15/266,170 patent/US20170081402A1/en active Pending
- 2016-09-15 MX MX2018003174A patent/MX2018003174A/es unknown
- 2016-09-15 IL IL302197A patent/IL302197A/en unknown
- 2016-09-15 EP EP16771052.4A patent/EP3350221A1/en active Pending
- 2016-09-15 AU AU2016323152A patent/AU2016323152A1/en not_active Abandoned
- 2016-09-15 CN CN201680054412.0A patent/CN108026168A/zh active Pending
- 2016-09-15 WO PCT/US2016/051844 patent/WO2017048901A1/en active Application Filing
- 2016-09-15 EA EA201890747A patent/EA201890747A1/ru unknown
- 2016-09-15 KR KR1020187010883A patent/KR20180053395A/ko not_active Application Discontinuation
-
2018
- 2018-02-15 IL IL257561A patent/IL257561A/en unknown
- 2018-03-07 CL CL2018000597A patent/CL2018000597A1/es unknown
- 2018-03-14 MX MX2022015250A patent/MX2022015250A/es unknown
- 2018-03-14 MX MX2022015248A patent/MX2022015248A/es unknown
- 2018-03-16 PH PH12018500578A patent/PH12018500578A1/en unknown
- 2018-09-05 HK HK18111369.0A patent/HK1252037A1/zh unknown
-
2020
- 2020-02-26 JP JP2020030579A patent/JP2020100643A/ja active Pending
- 2020-02-26 JP JP2020030580A patent/JP7000476B2/ja active Active
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2021
- 2021-12-23 JP JP2021209087A patent/JP7477492B2/ja active Active
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2022
- 2022-03-23 JP JP2022046728A patent/JP2022088478A/ja active Pending
-
2023
- 2023-06-06 AU AU2023203530A patent/AU2023203530A1/en active Pending
-
2024
- 2024-04-12 JP JP2024064412A patent/JP2024096863A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2020100643A (ja) | 2020-07-02 |
KR20180053395A (ko) | 2018-05-21 |
CN108026168A (zh) | 2018-05-11 |
EP3350221A1 (en) | 2018-07-25 |
AU2016323152A1 (en) | 2018-02-22 |
JP6668461B2 (ja) | 2020-03-18 |
HK1252037A1 (zh) | 2019-05-10 |
IL302197A (en) | 2023-06-01 |
AU2023203530A1 (en) | 2023-07-06 |
TW202138008A (zh) | 2021-10-16 |
US20170081402A1 (en) | 2017-03-23 |
JP2022088478A (ja) | 2022-06-14 |
JP2018527380A (ja) | 2018-09-20 |
JP2024096863A (ja) | 2024-07-17 |
MX2022015248A (es) | 2023-01-11 |
MX2018003174A (es) | 2018-05-17 |
TW201722474A (zh) | 2017-07-01 |
TWI733695B (zh) | 2021-07-21 |
MX2022015250A (es) | 2023-01-11 |
JP7000476B2 (ja) | 2022-02-04 |
CA2996645A1 (en) | 2017-03-23 |
JP2020100644A (ja) | 2020-07-02 |
IL257561A (en) | 2018-04-30 |
PH12018500578A1 (en) | 2018-09-10 |
WO2017048901A1 (en) | 2017-03-23 |
TWI811716B (zh) | 2023-08-11 |
JP2022046624A (ja) | 2022-03-23 |
JP7477492B2 (ja) | 2024-05-01 |
BR112018003526A2 (pt) | 2018-09-25 |
EA201890747A1 (ru) | 2018-10-31 |
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