CL2013002908A1 - Uso de compuestos derivados de bencimidazol-4-carboxamida para el tratamiento profilactico de la neuropatia periferica inducida por quimioterapia . - Google Patents
Uso de compuestos derivados de bencimidazol-4-carboxamida para el tratamiento profilactico de la neuropatia periferica inducida por quimioterapia .Info
- Publication number
- CL2013002908A1 CL2013002908A1 CL2013002908A CL2013002908A CL2013002908A1 CL 2013002908 A1 CL2013002908 A1 CL 2013002908A1 CL 2013002908 A CL2013002908 A CL 2013002908A CL 2013002908 A CL2013002908 A CL 2013002908A CL 2013002908 A1 CL2013002908 A1 CL 2013002908A1
- Authority
- CL
- Chile
- Prior art keywords
- benzimidazol
- carboxamide
- chemotherapy
- prophylactic treatment
- peripheral neuropathy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161473970P | 2011-04-11 | 2011-04-11 | |
US201161476616P | 2011-04-18 | 2011-04-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2013002908A1 true CL2013002908A1 (es) | 2013-12-06 |
Family
ID=45976523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2013002908A CL2013002908A1 (es) | 2011-04-11 | 2013-10-10 | Uso de compuestos derivados de bencimidazol-4-carboxamida para el tratamiento profilactico de la neuropatia periferica inducida por quimioterapia . |
Country Status (17)
Country | Link |
---|---|
US (2) | US20120258180A1 (es) |
EP (1) | EP2696870A1 (es) |
JP (1) | JP2014510787A (es) |
CN (1) | CN103687597A (es) |
AR (1) | AR085976A1 (es) |
AU (1) | AU2012243132A1 (es) |
BR (1) | BR112013026327A2 (es) |
CA (1) | CA2832817A1 (es) |
CL (1) | CL2013002908A1 (es) |
DO (1) | DOP2013000236A (es) |
IL (1) | IL228719A0 (es) |
MX (1) | MX2013011932A (es) |
NZ (1) | NZ616227A (es) |
RU (1) | RU2013150102A (es) |
SG (2) | SG2014014294A (es) |
TW (1) | TW201244714A (es) |
WO (1) | WO2012141990A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8828391B2 (en) * | 2011-05-17 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Method for EGFR directed combination treatment of non-small cell lung cancer |
US20160151339A1 (en) * | 2013-03-21 | 2016-06-02 | Hossein A. Ghanbari | Treatment for Chemotherapy-Induced Peripheral Neuropathy |
US20140287021A1 (en) * | 2013-03-21 | 2014-09-25 | Panacea Pharmaceuticals | Treatment of chemotherapy-induced peripheral neuropathy |
LT3325623T (lt) | 2015-07-23 | 2019-10-25 | Inst Curie | Dbait molekulės ir parp inhibitorių derinio panaudojimas vėžiui gydyti |
WO2018162439A1 (en) | 2017-03-08 | 2018-09-13 | Onxeo | New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule |
KR102633957B1 (ko) * | 2017-03-31 | 2024-02-06 | 도레이 카부시키가이샤 | 말초신경장해의 치료제 또는 예방제 |
CA3092779A1 (en) | 2018-03-13 | 2019-09-19 | Onxeo | A dbait molecule against acquired resistance in the treatment of cancer |
JP2022512927A (ja) * | 2018-11-08 | 2022-02-07 | イン8バイオ、インコーポレイテッド | 癌を処置するための組成物および方法 |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
ES2981848T3 (es) * | 2020-09-22 | 2024-10-10 | Anilur Pharma S L | C-ficocianina para usar en el tratamiento y/o la prevención de la neuropatía periférica |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2006206512B2 (en) * | 2005-01-19 | 2012-09-13 | Eisai Inc. | Diazabenzo(de)anthracen-3-one compounds and methods for inhibiting PARP |
TWI375673B (en) | 2005-04-11 | 2012-11-01 | Abbott Lab | 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors |
PT2338487E (pt) | 2006-01-17 | 2013-12-16 | Abbvie Bahamas Ltd | Terapia de combinação com inibidores de parp |
HUE027641T2 (en) | 2006-12-28 | 2016-11-28 | Abbvie Inc | Poly (ADP-ribose) polymerase inhibitors |
CN102083314B (zh) * | 2007-10-03 | 2014-04-30 | 卫材股份有限公司 | Parp抑制剂化合物、组合物以及使用方法 |
CN101821269B (zh) * | 2007-10-12 | 2014-05-28 | 艾伯维巴哈马有限公司 | 2-((r)-2-甲基吡咯烷-2-基)-1h-苯并咪唑-4-甲酰胺晶形2 |
-
2012
- 2012-04-09 TW TW101112503A patent/TW201244714A/zh unknown
- 2012-04-09 SG SG2014014294A patent/SG2014014294A/en unknown
- 2012-04-09 WO PCT/US2012/032724 patent/WO2012141990A1/en active Application Filing
- 2012-04-09 JP JP2014505198A patent/JP2014510787A/ja active Pending
- 2012-04-09 SG SG2013075098A patent/SG194138A1/en unknown
- 2012-04-09 EP EP12715262.7A patent/EP2696870A1/en not_active Withdrawn
- 2012-04-09 CN CN201280028608.4A patent/CN103687597A/zh active Pending
- 2012-04-09 CA CA2832817A patent/CA2832817A1/en not_active Abandoned
- 2012-04-09 AU AU2012243132A patent/AU2012243132A1/en not_active Abandoned
- 2012-04-09 RU RU2013150102/15A patent/RU2013150102A/ru not_active Application Discontinuation
- 2012-04-09 US US13/442,294 patent/US20120258180A1/en not_active Abandoned
- 2012-04-09 NZ NZ616227A patent/NZ616227A/en not_active IP Right Cessation
- 2012-04-09 BR BR112013026327A patent/BR112013026327A2/pt not_active IP Right Cessation
- 2012-04-09 MX MX2013011932A patent/MX2013011932A/es not_active Application Discontinuation
- 2012-04-11 AR ARP120101238A patent/AR085976A1/es unknown
-
2013
- 2013-10-03 IL IL228719A patent/IL228719A0/en unknown
- 2013-10-10 DO DO2013000236A patent/DOP2013000236A/es unknown
- 2013-10-10 CL CL2013002908A patent/CL2013002908A1/es unknown
- 2013-12-05 US US14/098,128 patent/US20140093585A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NZ616227A (en) | 2016-01-29 |
IL228719A0 (en) | 2013-12-31 |
AR085976A1 (es) | 2013-11-06 |
US20120258180A1 (en) | 2012-10-11 |
AU2012243132A1 (en) | 2013-10-24 |
SG2014014294A (en) | 2014-06-27 |
TW201244714A (en) | 2012-11-16 |
SG194138A1 (en) | 2013-11-29 |
BR112013026327A2 (pt) | 2019-09-24 |
WO2012141990A1 (en) | 2012-10-18 |
JP2014510787A (ja) | 2014-05-01 |
MX2013011932A (es) | 2013-11-01 |
RU2013150102A (ru) | 2015-05-20 |
US20140093585A1 (en) | 2014-04-03 |
DOP2013000236A (es) | 2014-01-15 |
EP2696870A1 (en) | 2014-02-19 |
CN103687597A (zh) | 2014-03-26 |
CA2832817A1 (en) | 2012-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LTPA2020510I1 (lt) | Pakeistieji 4-fenil-piridinai, skirti su NK-receptoriumi susijusių ligų gydymui | |
CL2013002908A1 (es) | Uso de compuestos derivados de bencimidazol-4-carboxamida para el tratamiento profilactico de la neuropatia periferica inducida por quimioterapia . | |
BR112014010206A2 (pt) | composto, composição farmacêutica, uso de composto, e, método para a profilaxia ou tratamento de um estado ou condição de doença | |
BR112014010179A8 (pt) | composto, composição farmacêutica, uso de um composto, e, método para a profilaxia ou tratamento de um estado ou condição | |
CL2014002873A1 (es) | Compuestos derivados de pirimidin-amina o triazin-amina, inhibidores de adn-pk; composicion farmaceutica; y su uso para el tratamiento del cancer. | |
CL2015000873A1 (es) | Métodos para el tratamiento del síndrome de alport. | |
BR112014010177A2 (pt) | composto, composição farmacêutica, uso do composto, e, método para a profilaxia ou tratamento de um estado ou uma condição de doença | |
CL2014000543A1 (es) | Compuestos derivados de imidazopiridazinas sustituidas con amino, inhibidores de la quinasa ,mknk2; metodo de preparacion; compuestos intermediarios y su uso; composicion farmaceutica; combinacion farmaceutica; y su uso para el tratamiento del cancer. | |
BR112015011112A2 (pt) | composto oligomérico, oligômero, composição farmacêutica, uso do composto oligomérico, método de síntese de um composto oligomérico e método de tratamento de uma doença. | |
BR112014000033A2 (pt) | compostos para o tratamento de dependência química | |
BR112014026802A2 (pt) | processo para a preparação de um a, \omega-cn diol. | |
CL2013003686A1 (es) | Compuestos derivados de ergolina, antagonista del receptor de 5-ht1d; útiles para el tratamiento de la migraña. | |
BR112013020024A2 (pt) | materiais para dispositivo oftálmico hidrófobo de baixa pegajosidade. | |
ES2603028T8 (es) | Procedimiento para la preparación de (Z)-alfa-fluoro-beta-amino-acrilaldehídos sustituidos | |
BR112013034055A2 (pt) | alcaftadina para uso no tratamento de urticária | |
CL2014001861A1 (es) | Compuestos derivados de bencil sulfonamida, inhibidores de mogat-2; compuesto cristalino; composicion farmaceutica; y su uso en el tratamiento de la hipertrigliceridemia. | |
BR112012016786A2 (pt) | Processos para preparar 7-metil-5-(3-piperazin-1-ilmetil-[1,2,4]oxadiazol-5-il)-2-(4- trifluorometoxibenzil)-2 | |
BR112013025715A2 (pt) | métodos para a deformação mecânica de materiais. | |
IL232194A (en) | An iontophoresis cross-linking preparation for use in keratoconus treatment | |
CL2014001862A1 (es) | Compuestos derivados de morofolinilo sustituido, útiles como inhibidores de mogat-2; composicion farmaceutica que los comprende; uso en el tratamiento de hipertrigliceridemia. | |
CL2013002903A1 (es) | Composicion que comprende azadiractina; metodo para el tratamiento anti-macroincrustacion de al menos un polimeros; y su uso. | |
BR112015005627A2 (pt) | composto, composição farmacêutica, uso de composto, método de tratamento e invenção. | |
IT1405996B1 (it) | Procedimento per la preparazione di 2,5-diaminotoluolo | |
ITMI20120739A1 (it) | Collare di serraggio incernierato. | |
IT1403597B1 (it) | Procedimento per il trattamento di materiali tessili |