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CL2012000520A1 - Anticuerpo o fragmento de union a antigeno del mismo capaz de unirse a dll4 humana; conjugado que comprende a dicho anticuerpo; vector aislado y celula huesped; metodo para producir dicho anticuerpo; composicion farmaceutica que lo comprende; y uso medico de dicho anticuerpo. - Google Patents

Anticuerpo o fragmento de union a antigeno del mismo capaz de unirse a dll4 humana; conjugado que comprende a dicho anticuerpo; vector aislado y celula huesped; metodo para producir dicho anticuerpo; composicion farmaceutica que lo comprende; y uso medico de dicho anticuerpo.

Info

Publication number
CL2012000520A1
CL2012000520A1 CL2012000520A CL2012000520A CL2012000520A1 CL 2012000520 A1 CL2012000520 A1 CL 2012000520A1 CL 2012000520 A CL2012000520 A CL 2012000520A CL 2012000520 A CL2012000520 A CL 2012000520A CL 2012000520 A1 CL2012000520 A1 CL 2012000520A1
Authority
CL
Chile
Prior art keywords
antibody
host cell
human dll4
conjugate
antigen
Prior art date
Application number
CL2012000520A
Other languages
English (en)
Inventor
Lorenzo Benatuil
Erwin R Boghaert
Maria Harris
Jonathan A Hickson
Chung-Ming Hsieh
Yuliya Kutskova
Yingchun Li
Zhihong Liu
Susan Morgan-Lappe
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43035018&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2012000520(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of CL2012000520A1 publication Critical patent/CL2012000520A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2857Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, orphan receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
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Abstract

Proteína de unión a DLL4 humana; construcción de anticuerpo que comprende la proteína de unión antes mencionada; anticuerpo conjugado que comprende dicha proteína; ácido nucleico, vector y célula huésped que comprenden anticuerpo; composición para la liberación de una proteína; método para el tratamiento de un mamífero; método para disminuir la actividad del DLL4 humano.
CL2012000520A 2009-08-29 2012-02-28 Anticuerpo o fragmento de union a antigeno del mismo capaz de unirse a dll4 humana; conjugado que comprende a dicho anticuerpo; vector aislado y celula huesped; metodo para producir dicho anticuerpo; composicion farmaceutica que lo comprende; y uso medico de dicho anticuerpo. CL2012000520A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23815209P 2009-08-29 2009-08-29
US26172809P 2009-11-16 2009-11-16

Publications (1)

Publication Number Publication Date
CL2012000520A1 true CL2012000520A1 (es) 2013-07-12

Family

ID=43035018

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012000520A CL2012000520A1 (es) 2009-08-29 2012-02-28 Anticuerpo o fragmento de union a antigeno del mismo capaz de unirse a dll4 humana; conjugado que comprende a dicho anticuerpo; vector aislado y celula huesped; metodo para producir dicho anticuerpo; composicion farmaceutica que lo comprende; y uso medico de dicho anticuerpo.

Country Status (25)

Country Link
US (5) US8623358B2 (es)
EP (2) EP3029070A1 (es)
JP (2) JP5903382B2 (es)
KR (1) KR20120089659A (es)
CN (2) CN102741288B (es)
AR (1) AR077998A1 (es)
AU (2) AU2010286518C1 (es)
BR (1) BR112012004546A8 (es)
CA (2) CA2771575A1 (es)
CL (1) CL2012000520A1 (es)
CO (1) CO6612215A2 (es)
CR (1) CR20120105A (es)
DO (1) DOP2012000052A (es)
HK (1) HK1225743A1 (es)
IL (1) IL218401A (es)
MX (2) MX2012002605A (es)
MY (1) MY159837A (es)
NZ (1) NZ598524A (es)
PE (1) PE20121647A1 (es)
RU (1) RU2570639C2 (es)
SG (1) SG178930A1 (es)
TW (1) TWI465250B (es)
UY (1) UY32869A (es)
WO (1) WO2011025964A2 (es)
ZA (1) ZA201201298B (es)

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